Contributed by Tammy T. Hshieh, MD MPH, Associate Physician at Brigham and Women’s Hospital, Harvard Medical School and Research Faculty at the Aging Brain Center, Hebrew Senior Life NIDUS supports junior researchers by seeding pilot grants. I was fortunate to have received such an award in 2017. At the time, I had recently completed a […]
Contributed by Heidi Lindroth, RN, PhD, T32 Postdoctoral Fellow, Indiana University School of Medicine, Division of Pulmonary and Critical Care Medicine. Covid-19 has substantially changed the environment for patient care due to dramatically increasing patient volumes, personal protective equipment (PPE) shortages, stringent isolation and infection control activities, and severe restrictions on visitors and contact between […]
Contributed by Louise Rose, BN, MN, PhD, Professor in Critical Care Nursing, Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, King’s College London, London, UK Delirium is a common, costly and potentially preventable syndrome associated with short- and long-term adverse outcomes for patients, family members, and healthcare organizations. Reassuringly, the numbers of clinical trials […]
Contributed by Olga Boukrina, Ph.D., Kessler Foundation Delirium is a multicomponent syndrome produced by a set of unique vulnerabilities (e.g., infection, advanced age, decreased cognitive functioning) and compounding causes (e.g., circadian dysregulation, oxidative stress, neuronal aging). The contribution of each individual factor and their interactions present a complicated picture, but unifying themes in this line […]
Every other month, the Delirium Research Hub selects an investigator and research study included in the Delirium Research Hub to feature as a Spotlight Investigator. This month, we are featuring Dr. Olga Boukrina, PhD, for her study “Neglect and Delirium,” which investigates a potential neural mechanism underlying the link between delirium and spatial neglect in […]
Contributed by Heidi Lindroth PhD, RN, Postdoctoral Fellow at Indiana University School of Nursing and Indiana University School of Medicine, Center for Aging Research Upwards of 4 million hospitalized adults experience delirium, a form of acute brain failure each year.1-3 The measurement of delirium severity, defined as the intensity of a delirious episode, is growing […]
Contributed by Heidi Lindroth, BSN, RN, PhD Candidate, School of Nursing, Program Assistant, School of Medicine and Public Health, Department of Anesthesiology at The University of Wisconsin-Madison The American Delirium Society (ADS) annual conference was held in June 2018 to share the latest advancements in delirium science. A wide variety of topics from delirium training […]
Contributed by Olga Boukrina, PhD, Research Scientist, Stroke Rehabilitation Research at The Kessler Foundation Magnetic Resonance Imaging (MRI) offers an objective and quantitative measurement of brain health. The progress in MR imaging has made it possible to not only accurately measure brain volume, but also to assess the integrity of white matter connections in the […]
Contributed by Madeline D’Aquila, BS, Clinical Research Associate II & Annie Racine, PhD, MPA, both of the Institute for Aging Research, Harvard Medical School, Boston, MA. Although successful programs¹ to prevent delirium have been developed and implemented, advances in new prevention or treatment approaches have been stymied by a poor understanding of delirium pathophysiology. Neuroimaging […]
Contributed by Namrata Patil, MD MPH of Brigham & Women’s Hospital and Faculty at Harvard Medical School, Boston. “Doctor, is he still like that? If he is still the same I am not coming in….,” her voice cracks as she breaks into sobs on the other side of the phone. My patient’s wife does […]