Delirium Research Hub

The NIDUS Delirium Research Hub now has two databases of completed or ongoing studies that include delirium as an outcome or predictor. Our original Delirium Research Hub centers on human and population-based studies, and includes over 700 studies. In addition, our new Animal Models Hub contains basic research relevant to delirium, with over 100 studies.

The Hub includes study meta-data (like a “table of contents”) such as study design, sample characteristics, collected biospecimens, neuroimaging tests, neuropsychological testing and pharmacologic intervention. Specifically, the Hub allows researchers to search for studies on delirium. It also facilitates collaboration, secondary data analyses, and pilot studies to enable advances in the field of delirium research. What's more, each study entry includes contact information for the relevant study staff. Consequently, this allows researchers to develop connections and seek out existing data, resources, or information to complement their own research.

Access to the Research Hub is available to all delirium researchers through free registration as a NIDUS member on this site. We invite you to submit your own delirium studies via the Hub Study Submission Portal for inclusion in the Hub as well. Please see instructions below on how to enter a study.  If you have any questions, please contact us at nidus@hsl.harvard.edu.

Learn how to use the Delirium Research Hub and how to enter your study from Dr. Ed Marcantonio:

 

 

Human Delirium Research Hub

Search the Human Delirium Hub

Animal Delirium Research Hub

Search the Animal Delirium Hub

Have feedback about the Delirium Research Hub? We would love to hear from you.

Search for studies in the Research Hub

To help connect researchers with potential collaborators and study data, we developed the Delirium Research Hub Resource Finder. This web-based application allows users to search, view and export information about studies entered into the Hub.

You can search for specific information in the Hub using the Resource Finder. Or use the sort and filter options to find studies relevant to your work. You can also download PDF summaries of specific studies, or export excel files for multiple studies.

Please note, in order to access the Hub, you will need to create or log in to your free deliriumnetwork.org account.

Delirium Research Hub Study Submission Portal: Enter your study to the Hub

If you have a completed or ongoing study involving delirium as a predictor or outcome that you would like to submit to the NIDUS Delirium Research Hub, please review the information below to learn how to submit your study.  

To submit your study, you must complete the study entry form. It solicits basic information about the study to be included in the database. Completion of the form takes less than 20 minutes.

Inclusion criteria for the Human Subjects Hub

  1. Human studies including genetic, biomarker and neuroimaging studies
  2. Delirium as either the primary or secondary outcome, or predictor
  3. Minimum sample size=20
  4. Any study within a larger study that uses a distinctly different sample, adds new types of measures (e.g. imaging, biomarkers), or has a different Principal Investigator should be entered separately. Sub-studies using the same sample and measures as the parent study and with the same PI should not be re-entered.

Inclusion criteria for the Animal Models Hub

  1. Animal models studies directly relevant to delirium pathophysiology
  2. Model system should be well characterized (type of animal, age, sex, etc.)
  3. Method for inducing stress or delirium should be well characterized
  4. Outcome measures such as behavioral studies, blood and tissue biomarkers, imaging, and/or neurophysiological studies

For questions, contact the NIDUS Research Resource Core at nidus@hsl.harvard.edu.

To complete an entry in our database, you need the following information

  • A deliriumnetwork.org account; register an account for free on this page or log in using a Google account
  • Primary contact person for study AND Study PI contact information (email address and phone number)
  • Basic information about your study including, but not limited to:
    • study design
    • sample size
    • citations for journal articles which describe your study methods
    • an abstract describing study methods and results (could be abstract from primary study paper, poster, etc.).
    • specific information about your study population (size, age, inclusion/exclusion criteria)
    • specific information about your study methods (interventions used, if applicable, types of delirium measures used, types of samples or neuroimaging collected)
    • general information about current study status and availability of data for sharing and collaboration
  • Please note: information submitted to the Hub, including contact information, will be publicly accessible via the resource browser
Have you used the Delirium Research Hub?

Now that there are hundreds of delirium studies listed, we'd like to hear your story. Please email us your story about how the Hub has been useful to you. Check back because you and your research might be featured on the NIDUS website!