Tammy T. Hshieh

Does Alzheimer’s Disease and Related Dementias Modify Delirium Severity and Hospital Outcomes?

Contributed by Tammy T. Hshieh, MD MPH, Associate Physician at Brigham and Women’s Hospital, Harvard Medical School and Research Faculty at the Aging Brain Center, Hebrew Senior Life NIDUS supports junior researchers by seeding pilot grants. I was fortunate to have received such an award in 2017. At the time, I had recently completed a […]

Preventing Delirium During Covid-19 with Evidence-Based Tools

Contributed by Heidi Lindroth, RN, PhD, T32 Postdoctoral Fellow, Indiana University School of Medicine, Division of Pulmonary and Critical Care Medicine. Covid-19 has substantially changed the environment for patient care due to dramatically increasing patient volumes, personal protective equipment (PPE) shortages, stringent isolation and infection control activities, and severe restrictions on visitors and contact between […]

Core Outcome Sets for Trials to Prevent and/or Treat Delirium: The Del-COrS Collaboration

Contributed by Louise Rose, BN, MN, PhD, Professor in Critical Care Nursing, Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, King’s College London, London, UK Delirium is a common, costly and potentially preventable syndrome associated with short- and long-term adverse outcomes for patients, family members, and healthcare organizations. Reassuringly, the numbers of clinical trials […]

Olga Boukrina

Possible role for the CNS arousal network in delirium

Contributed by Olga Boukrina, Ph.D., Kessler Foundation Delirium is a multicomponent syndrome produced by a set of unique vulnerabilities (e.g., infection, advanced age, decreased cognitive functioning) and compounding causes (e.g., circadian dysregulation, oxidative stress, neuronal aging). The contribution of each individual factor and their interactions present a complicated picture, but unifying themes in this line […]