News and Announcements

This page includes all NIDUS announcements, updates and news. We will also feature a new article from the Hospital Elder Life Program Delirium Bibliography each month on this page.

NIDUS Clinical Trials Webinar with Dr. Wes Ely and Dr. Pratik Pandharipande on December 12 at 12pm EST! Link to webinar and more info here. The webinar is free with NO pre-registration required!

New Randomized Clinical Trial Demonstrates Effectiveness of Adapted Hospital Elder Life Program

A new randomized controlled trial in JAMA Internal Medicine has demonstrated the effectiveness of the Hospital Elder Life Program (HELP), this time in an adapted, tailored format. The HELP Program reduces delirium and functional decline in hospitalized older adults through daily interventions, many of which are performed by volunteers.

This study enrolled 281 surgical patients at a hospital in China and compared a group receiving a tailored version of the HELP program (t-HELP) to a group receiving usual care with no HELP program. T-HELP included non-pharmacological interventions completed by family members (instead of volunteers) trained by nursing staff. Results demonstrated the effectiveness of this t-HELP format, as occurrence of delirium was only 2.6% in the t-HELP group while 19.4% in the usual care group. And even further, patients who received t-HELP program had greater recovery (both cognitive and functional) one month after surgery compared to the usual care group.

This is a very important study, as in China, family members are frequently involved in care of older persons but hospitals often do not utilize volunteers. This study demonstrates that HELP can be adapted to fit a variety of institutional formats. Read more about the study here: https://scienmag.com/family-members-can-assist-in-preventing-post-operative-delirium-by-as-much-as-16-8/ 

NIDUS is offering four 1-year pilot awards $50k each for new research projects related to delirium! See more info here!

Dr. Inouye's interview, "Delirium, Dementia, and the Brain", is featured in The Harvard Mahoney Neuroscience Institute Letter!

2019 NIDUS Pilot Grant Overview Webinar

Link to recording of webinar here.

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Delirium Research Hub Investigator Spotlight: Olga Boukrina

Every other month, the Delirium Research Hub selects an investigator and research study included in the Delirium Research Hub to feature as a Spotlight Investigator. This month, we are featuring Dr. Olga Boukrina, PhD, for her study “Neglect and Delirium,” which investigates a potential neural mechanism underlying the link between delirium and spatial neglect in […]

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Delirium Research Hub Investigator Spotlight: Chris Hughes

Every other month, the Delirium Research Hub selects an investigator and research study included in the Delirium Research Hub to feature as a Spotlight Investigator. This month, we are featuring Dr. Chris Hughes, MD, for his study “Role of Endothelial and Brain Injury in Acute and Long-term Brain Dysfunction,” which observed that higher levels of […]

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Delirium Research Hub Investigator Spotlight: Tanya Mailhot

Each month, the Delirium Research Hub selects an investigator and research study included in the Delirium Research Hub to feature as a Spotlight Investigator. This month, we are featuring Dr. Tanya Mailhot, PhD, RN for her study, “Evaluation of a Nurse Mentoring Intervention with Family Caregivers in the Management of Delirium (MENTOR_D)” which piloted a […]

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Systematic Review of Delirium Severity Measurement

Contributed by Heidi Lindroth PhD, RN, Postdoctoral Fellow at Indiana University School of Nursing and Indiana University School of Medicine, Center for Aging Research Upwards of 4 million hospitalized adults experience delirium, a form of acute brain failure each year.1-3 The measurement of delirium severity, defined as the intensity of a delirious episode, is growing […]

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Delirium Research Profile: Charles Adrian Austin, MD, MSCR

Interview by Claire Horne, Communications Specialist, UNC Center for Aging and Health. Adrian Austin is a pulmonary critical care physician, geriatrician, and delirium researcher at University of North Carolina-Chapel Hill. He leads the UNC-CH working group of investigators (“I-DUNC”) for better delirium assessment and education. Adrian currently has two delirium-related pilot studies underway at UNC: […]