Delirium Bibliography

The searchable delirium bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons.  The NIDUS team keeps it updated for you on a monthly basis!  Feel free to search by author, title, year, keywords. It is primarily intended for clinicians and researchers interested in exploring these topics.

To retrieve full information, click on the title of the article and scroll down to read the abstract, journal, etc.

Each article is indexed by keywords taken from MEDLINE and other relevant databases.

You may base your search on as many search terms as you like. A search term can be a keyword, an author’s name, all or part of an article’s title, or the year of publication.

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Total Records Found: 4595, showing 100 per page
TitleAuthorsJournalYearKeywords
Inclusion of interleukin-6 improved performance of postoperative delirium prediction for patients undergoing coronary artery bypass graft (POD-CABG): A derivation and validation study Zhang, S. Ji, M. H. Ding, S. Wu, Y. Feng, X. W. Tao, X. J. Liu, W. W. Ma, R. Y. Wu, F. Q. Chen, Y. L. J Cardiol 2021

Coronary artery bypass graft surgery
Interleukin-6
Postoperative delirium
Prediction rule
interest

DNA methylation in the TNF-alpha gene decreases along with aging among delirium inpatients Yamanashi, T. Saito, T. Yu, T. Alario, A. Comp, K. Crutchley, K. J. Sullivan, E. J. Anderson, Z. M. Marra, P. S. Chang, G. Wahba, N. E. Jellison, S. S. Meyer, A. A. Mathur, S. Pandharipande, P. Yoshino, A. Kaneko, K. Lee, S. Toda, H. Iwata, M. Shinozaki, Neurobiol Aging 2021

Aged
Aging/*genetics
Cohort Studies
CpG Islands/genetics
DNA Methylation/*genetics
Delirium/etiology/*genetics
Female
Genome-Wide Association Study/methods
High-Throughput Nucleotide Sequencing
Humans
Inflammation
*Inpatients
Male
Tumor Necrosis Factor-alpha/*genetics
*Aging
*DNA methylation
*Delirium
*EPIC array
*Pyrosequencing
*TNF-alpha

DNA methylation in the inflammatory genes after neurosurgery and diagnostic ability of post-operative delirium Yamanashi, T. Nagao, T. Wahba, N. E. Marra, P. S. Crutchley, K. J. Meyer, A. A. Andreasen, A. J. Hellman, M. M. Jellison, S. S. Hughes, C. G. Pandharipande, P. P. Howard Iii, M. A. Kawasaki, H. Iwata, M. Hefti, M. M. Shinozaki, G. Transl Psychiatry 2021
Intraoperative hypotension and delirium among older adults undergoing transcatheter aortic valve replacement Wesselink, E. M. Abawi, M. Kooistra, N. H. M. Kappen, T. H. Agostoni, P. Emmelot-Vonk, M. Pasma, W. van Klei, W. A. van Jaarsveld, R. C. van Dongen, C. S. Doevendans, Pafm Slooter, A. J. C. Stella, P. R. J Am Geriatr Soc 2021

Aged, 80 and over
Anesthesia, General/*adverse effects
Delirium/*epidemiology
Female
Humans
Hypotension/*etiology
Intraoperative Complications/*chemically induced
Male
Netherlands
Postoperative Complications/*chemically induced
Retrospective Studies
Risk Factors
Transcatheter Aortic Valve Replacement/*adverse effects
Treatment Outcome
*tavr
*delirium
*intraoperative hypotension
*transcatheter aortic valve replacement

Patterns of Delirium in a Pediatric Intensive Care Unit and Associations With Noise Pollution Weatherhead, J. R. Niedner, M. Dahmer, M. K. Malas, N. Owens, T. Kawai, Y. J Intensive Care Med 2021

delirium
noise pollution
patient safety
pediatric intensive care unit
quality improvement
sleep

Gender Differences and Postoperative Delirium in Adult Patients Undergoing Cardiac Valve Surgery Wang, H. Guo, X. Zhu, X. Li, Y. Jia, Y. Zhang, Z. Yuan, S. Yan, F. Front Cardiovasc Med 2021

adult
cardiac surgery
gender
postoperative delirium
risk factor

Comparison of restrictive fluid therapy with goal-directed fluid therapy for postoperative delirium in patients undergoing spine surgery: a randomized controlled trial Wang, D. D. Li, Y. Hu, X. W. Zhang, M. C. Xu, X. M. Tang, J. Perioper Med (Lond) 2021

Goal-directed fluid therapy
Postoperative delirium
Restrictive fluid therapy
Spinal surgery
manuscript.

Effect of dexmedetomidine on postoperative delirium in patients undergoing brain tumour resections: study protocol of a randomised controlled trial Wang, D. Li, R. Li, S. Wang, J. Zeng, M. Dong, J. Liu, X. Lin, N. Peng, Y. BMJ Open 2021

*Brain Neoplasms
Craniotomy/adverse effects
*Delirium/epidemiology/etiology/prevention & control
*Dexmedetomidine/therapeutic use
Double-Blind Method
Humans
Prospective Studies
Randomized Controlled Trials as Topic
*delirium & cognitive disorders
*head & neck tumours
*neurosurgery

Association of preoperative frailty with postoperative delirium after elective brain tumor resection: Retrospective analysis of a prospective cohort Wang, C. M. Ma, Y. L. Yang, X. Y. Ji, R. Q. Gu, W. J. Zhou, J. X. Surgery 2021

Adult
Aged
Brain Neoplasms/complications/economics/*surgery
Craniotomy/*adverse effects
Elective Surgical Procedures/*adverse effects
Emergence Delirium/diagnosis/*epidemiology/etiology
Female
Frailty/diagnosis/*epidemiology
Geriatric Assessment/statistics & numerical data
Health Care Costs/statistics & numerical data
Humans
Length of Stay/economics/statistics & numerical data
Male
Middle Aged
Prospective Studies
Retrospective Studies
Risk Assessment
Risk Factors

Delirium and other neuropsychiatric manifestations of COVID-19 infection in people with preexisting psychiatric disorders: a systematic review van Reekum, E. A. Rosic, T. Sergeant, A. Sanger, N. Rodrigues, M. Rebinsky, R. Panesar, B. Deck, E. Kim, N. Woo, J. D'Elia, A. Hillmer, A. Dufort, A. Sanger, S. Thabane, L. Mbuagbaw, L. Samaan, Z. J Med Case Rep 2021

Bias
*covid-19
*Delirium/epidemiology
Humans
Pandemics
SARS-CoV-2
Covid-19
Case reports
Delirium
Internal medicine
Mental disorders
Pandemic
Psychiatric disorder
Systematic review

Suvorexant with or without ramelteon to prevent delirium: a systematic review and meta-analysis Tian, Y. Qin, Z. Han, Y. Psychogeriatrics 2021

delirium
ramelteon
suvorexant
systematic review and meta-analysis

Nurses' Experience of Caring for Patients with Delirium: Systematic Review and Qualitative Evidence Synthesis Thomas, N. Coleman, M. Terry, D. Nurs Rep 2021

anxiety
assessment
delirium
education
nurse
patient
peers
stress
support

Understanding the decision-making of critical care nurses when restraining a patient with psychomotor agitation secondary to hyperactive delirium: A 'Think Aloud' study Teece, A. Baker, J. Smith, H J Clin Nurs 2022

Critical Care
*Delirium
Humans
*Nursing Staff, Hospital
Psychomotor Agitation
Restraint, Physical

Reduced Electroencephalogram Complexity in Postoperative Delirium Tanabe, S. Parker, M. Lennertz, R. Pearce, R. A. Banks, M. I. Sanders, R. D. J Gerontol A Biol Sci Med Sci 2021

*Age-related pathology
*Inflammation
*Neurodegeneration

Using Telehealth to Improve the Accuracy of Delirium Screening by Bedside Critical Care Nurses Sinvani, L. Hertz, C. Chandra, S. Ilyas, A. Ardito, S. Hajizadeh, N. Am J Crit Care 2022
Melatonin for prevention of postoperative delirium after lower limb fracture surgery in elderly patients (DELIRLESS): study protocol for a multicentre randomised controlled trial Sigaut, S. Couffignal, C. Esposito-Farèse, M. Degos, V. Molliex, S. Boddaert, J. Raynaud-Simon, A. Durand-Zaleski, I. Marcault, E. Jacota, M. Dahmani, S. Paugam-Burtz, C. Weiss, E. BMJ Open 2021

anaesthesia in orthopaedics
delirium & cognitive disorders
geriatric medicine
hip

Management of delirium in a medical and surgical intensive care unit Shivji, S. Stabler, S. N. Boyce, K. Haljan, G. J. McGloin, R. J Clin Pharm Ther 2021

Aged
Antipsychotic Agents/adverse effects/*therapeutic use
Comorbidity
Delirium/*drug therapy/*epidemiology/therapy
Female
Humans
Intensive Care Units/*organization & administration
Male
Middle Aged
Recurrence
*Respiration, Artificial
Retrospective Studies
Tertiary Care Centers
Time Factors
critical care
delirium
dexmedetomidine
haloperidol
mechanical ventilation
quetiapine

5-HT(3) receptor antagonists decrease the prevalence of postoperative delirium in older patients undergoing orthopedic lower limb surgery Shin, H. J. Yoon, J. Na, H. S. Perioper Med (Lond) 2021

5-HT3 receptor antagonist
Older patient
Postoperative delirium

Neutrophil-Lymphocyte Ratio as a Potential Biomarker for Delirium in the Intensive Care Unit Seo, C. L. Park, J. Y. Park, J. Kim, H. E. Cho, J. Seok, J. H. Kim, J. J. Shin, C. S. Oh, J. Front Psychiatry 2021

C-reactive protein
delirium
inflammatory markers
intensive care unit
neutrophil-lymphocyte ratio

Diagnosis and management of delirium in hospital oncology service Ramírez Zuluaga, L. P. Ruano Restrepo, M. I. Osorio Bermúdez, J. D. Díaz Vallejo, J. A. J Geriatr Oncol 2021

Cancer
Delirium
Hospital oncology services

Preschool Confusion Assessment Method for the Intensive Care Unit-Spanish (psCAM-ICU-S): Cross-Cultural Adaptation and Validation in Colombia Pinzón-Casas, E. Soto-Trujillo, M. Camargo-Agón, L. Henao-Castaño, Á Gualdrón, N. Bonilla-González, C. Front Pediatr 2021

delirium
intensive care units
pediatric
preschool
psychiatry
validation study

Baseline Vulnerabilities May Play a Larger Role than Depth of Anesthesia or Sedation in Postoperative Delirium Pandharipande, P. P. Whitlock, E. L. Hughes, C. G. Anesthesiology 2021

*Anesthesia
*Delirium
Humans

Prediction of Postoperative Delirium in Geriatric Hip Fracture Patients: A Clinical Prediction Model Using Machine Learning Algorithms Oosterhoff, J. H. F. Karhade, A. V. Oberai, T. Franco-Garcia, E. Doornberg, J. N. Schwab, J. H. Geriatr Orthop Surg Rehabil 2021

clinical prediction model
delirium
geriatric trauma
hip fracture
machine learning
personalized medicine

REcognizing DElirium in geriatric Emergency Medicine: The REDEEM risk stratification score Oliveira, J. E. Silva L. Stanich, J. A. Jeffery, M. M. Mullan, A. F. Bower, S. M. Campbell, R. L. Rabinstein, A. A. Pignolo, R. J. Bellolio, F. Acad Emerg Med 2021
Evaluation of the 3-Minute Diagnostic Confusion Assessment Method for Identification of Postoperative Delirium in Older Patients Oberhaus, J. Wang, W. Mickle, A. M. Becker, J. Tedeschi, C. Maybrier, H. R. Upadhyayula, R. T. Muench, M. R. Lin, N. Schmitt, E. M. Inouye, S. K. Avidan, M. S. JAMA Netw Open 2021
Is delirium associated with negative outcomes in older patients with hip fracture: analysis of the 4904 patients 2017-2018 from the Australian and New Zealand hip fracture registry Oberai, T. Woodman, R. Laver, K. Crotty, M. Kerkhoffs, G. Jaarsma, R ANZ J Surg 2021

delirium
hip fracture
outcomes

Postoperative delirium in older patients with cancer: the role of psychological distress and social support O'Hanlon, S. Baxter, M. Hosie, A. Curr Opin Support Palliat Care 2021
Postoperative delirium and neurocognitive disorders Migirov, A. Chahar, P. Maheshwari, K. Curr Opin Crit Care 2021

Aging
*Delirium/diagnosis/etiology/therapy
Humans
Neurocognitive Disorders
*Postoperative Complications/etiology
Postoperative Period

Development of a delirium predictive model for adult trauma patients in an emergency and critical care center: a retrospective study Matsuoka, A. Miike, T. Miyazaki, M. Goto, T. Sasaki, A. Yamazaki, H. Komaki, M. Higuchi, M. Mori, K. Shinada, K. Nakayama, K. Sakurai, R. Asahi, M. Futami, A. Yoshitake, K. Narumi, S. Koba, M. Koami, H. Kawaguchi, A. Murakawa, T. H. Monji, A. Sakamoto, Y. Trauma Surg Acute Care Open 2021

adult
frailty
multiple trauma

Early-onset delirium after spontaneous intracerebral hemorrhage Marrama, F. Kyheng, M. Pasi, M. Pierre Rutgers, M. Moulin, S. Diomedi, M. Leys, D. Cordonnier, C. Hénon, H. Casolla, B. Int J Stroke 2021

Intracerebral hemorrhage
delirium
dementia
long-term outcomes
mortality

An Emergency Department Delirium Screening and Management Initiative: The Development and Refinement of the SCREENED-ED Intervention Mailhot, T. Saczynski, J. S. Malyuta, Y. Inouye, S. K. Darling, C. J Gerontol Nurs 2021

*Delirium/diagnosis/therapy
Delivery of Health Care
*Emergency Medical Services
Emergency Service, Hospital
Humans
Mass Screening

Impact of a multifaceted and multidisciplinary intervention on pain, agitation and delirium management in an intensive care unit: an experience of a Canadian community hospital in conducting a quality improvement project Ma, Z. Camargo Penuela, M. Law, M. Joshi, D. Chung, H. O. Lam, J. N. H. Tsang, J. L. BMJ Open Qual 2021

Canada
*Delirium/diagnosis/prevention & control
Hospitals, Community
Humans
Intensive Care Units
Pain
*Quality Improvement
Translational Science, Biomedical
*clinical practice guidelines
*critical care
*healthcare quality improvement
*implementation science

Prevalence, classification, risk factors and outcome impact of delirium in patients with COVID-19: a meta-analysis protocol for systematic review Lou, B. Guo, J. Liu, Y. Xiong, C. Shi, J. Zhou, C. BMJ Open 2021

*COVID-19/complications
*Delirium/complications/epidemiology
Humans
Meta-Analysis as Topic
Prevalence
Risk Factors
SARS-CoV-2
Systematic Reviews as Topic
*covid-19
*adult intensive & critical care
*delirium & cognitive disorders

Effect of Regional vs General Anesthesia on Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery: The RAGA Randomized Trial Li, T. Li, J. Yuan, L. Wu, J. Jiang, C. Daniels, J. Mehta, R. L. Wang, M. Yeung, J. Jackson, T. Melody, T. Jin, S. Yao, Y. Wu, J. Chen, J. Smith, F. G. Lian, Q. Jama 2021
Opioid and benzodiazepine use in the emergency department and the recognition of delirium within the first 24 hours of hospitalization Lee, S. Okoro, U. E. Swanson, M. B. Mohr, N. Faine, B. Carnahan, R. J Psychosom Res 2021

Delirium
Emergency department
High-risk medications
Prediction

Awareness and Perspectives among Asian Anesthesiologists on Postoperative Delirium: A Multinational Survey Lee, H. Kim, J. Lee, K. Y. Gan, T. J. Lekprasert, V. Laosuwan, P. Chew, S. T. H. Seet, E. Lim, V. Ti, L. K. J Clin Med 2021

NIR spectroscopy
anesthesiology
consciousness monitors
perioperative care
postoperative cognitive complications
postoperative complications

Utilization of Kotter's Stages and Statistical Process Control to Implement and Sustain Delirium Screening in PICU Kupferschmid, M. Tripathi, S. Pediatr Qual Saf 2021
Impact of postoperative delirium on days alive and at home after surgery: a prospective cohort study Kunkel, D. Parker, M. Casey, C. Krause, B. Pearce, R. A. Lennertz, R. Sanders, R. D. Br J Anaesth 2021

Cohort Studies
Delirium/*mortality
Humans
Length of Stay/*statistics & numerical data
Patient Acuity
Postoperative Complications/*mortality
Prospective Studies
*days alive and at home
*delirium
*mortality
*postoperative
*surgery

Delirium in a Tertiary Pediatric Cardiac Intensive Care Unit: Risk Factors and Outcomes Koth, A. M. Chan, T. Tjoeng, Y. L. Watson, R. S. Dervan, L. A. J Intensive Care Med 2021

analgesics
benzodiazepines
child
critical care
critical illness
dexmedetomidine
hypnotics and sedatives
length of stay
opioids
retrospective studies

Postoperative delirium screening tools for post-anaesthetic adult patients in non-intensive care units: A systematic review and meta-analysis Kim, S. Choi, E. Jung, Y. Jang, I. J Clin Nurs 2021

adult nursing
emergence delirium
nursing assessment
postoperative care
systematic review and meta-analyses

Factors Related to Delirium of Intensive Care Unit Patients in Korea: A Systematic Review Kim, N. Y. Ryu, S. A. Kim, Y. H. Iran J Public Health 2021

Delirium
Intensive care units
Systematic review

Risk factors for postoperative delirium in patients with colorectal cancer Kim, H. Park, H. Kim, E. K. J Clin Nurs 2022

*Colorectal Neoplasms/complications/surgery
Cross-Sectional Studies
*Delirium/epidemiology/etiology
Humans
Postoperative Complications/epidemiology
Risk Factors
colorectal cancer
delirium

Influences of remote ischemic preconditioning on postoperative delirium and cognitive dysfunction in adults after cardiac surgery: a meta-analysis of randomized controlled trials Jing, Y. Gao, B. Li, X. Perioper Med (Lond) 2021

Cardiac surgery
Meta-analysis
Postoperative cognitive dysfunction
Postoperative delirium
Remote ischemic preconditioning

Delirium Reduction by Analgesia Management in Hip Fracture surgery (DRAM-HF): Exploration of perceived facilitators and barriers Hunter, C. L. Ni Chroinin, D. McEvoy, L. Chuan, A. Australas J Ageing 2021

*Analgesia
*Delirium/diagnosis/drug therapy/prevention & control
*Hip Fractures/diagnosis/surgery
Humans
Pharmacists
Prospective Studies
delirium
hip fractures
perioperative care

Management of Delirium in the Intensive Care Unit Huang, D. D. Fischer, P. E. Surg Clin North Am 2022

Age Factors
Antipsychotic Agents/therapeutic use
Behavior Therapy/methods
Combined Modality Therapy
Critical Care/*methods
Delirium/diagnosis/etiology/*therapy
Humans
Intensive Care Units
Risk Factors
Antipsychotics
Delirium
Elderly
Intensive care unit
Prevention

Postoperative delirium and quality of life after transcatheter and surgical aortic valve replacement: A prospective observational study Hoogma, D. F. Venmans, E. Al Tmimi, L. Tournoy, J. Verbrugghe, P. Jacobs, S. Fieuws, S. Milisen, K. Adriaenssens, T. Dubois, C. Rex, S. J Thorac Cardiovasc Surg 2021

Savr
Tavi
aortic valve
cardiac surgery
delirium
frailty
postoperative outcome
quality of life

Construction and Application of a Model for Predicting the Risk of Delirium in Postoperative Patients With Type a Aortic Dissection He, J. Ling, Q. Chen, Y. Front Surg 2021

factor
nursing
postoperative delirium
predictive model
type A aortic dissection

The Locus Coeruleus Noradrenaline System in Delirium Hansen, N. Rediske, A. I. Front Aging Neurosci 2021

attention
cognition
delirium
locus coeruleus
noradrenaline

Single bolus dexmedetomidine versus propofol for treatment of pediatric emergence delirium following general anesthesia Han, X. Sun, X. Liu, X. Wang, Q Paediatr Anaesth 2021

dexmedetomidine
pediatric emergence delirium
propofol

Prospective Analysis Between Neutrophil-to-Lymphocyte Ratio on Admission and Development of Delirium Among Older Hospitalized Patients With COVID-19 Fernández-Jiménez, E. Muñoz-Sanjose, A. Mediavilla, R. Martínez-Alés, G. Louzao,, II Andreo, J. Cebolla, S. Bravo-Ortiz, M. F. Bayón, C. Front Aging Neurosci 2021

Covid-19
delirium
hospitalization
neutrophil-to-lymphocyte ratio (NLR)
older adults

Relationship Between Cerebral Hemodynamics, Tissue Oxygen Saturation, and Delirium in Patients With Septic Shock: A Pilot Observational Cohort Study Feng, Q. Ai, M. Huang, L. Peng, Q. Ai, Y. Zhang, L. Front Med (Lausanne) 2021

cerebral oxygen saturation
delirium
sepsis
sepsis-associated delirium
septic shock
tissue oxygen saturation
transcranial Doppler ultrasound

Risk factors for delirium in adult patients receiving specialist palliative care: A systematic review and meta-analysis Featherstone, I. Sheldon, T. Johnson, M. Woodhouse, R. Boland, J. W. Hosie, A. Lawlor, P. Russell, G. Bush, S. Siddiqi, N. Palliat Med 2021

Risk factors
delirium
meta-analysis
palliative care
systematic review

Feasibility trial of weighted blankets as an intervention for emergence delirium in postoperative pediatric patients Eull, D. Zachrison, B. Nickel, A. J Pediatr Nurs 2021

Emergence delirium
Feasibility
Post-anesthesia care unit (PACU)
Watcha scale
Weighted blanket

The LiberAction Project: Implementation of a Pediatric Liberation Bundle to Screen Delirium, Reduce Benzodiazepine Sedation, and Provide Early Mobilization in a Human Resource-Limited Pediatric Intensive Care Unit Di Nardo, M. Boldrini, F. Broccati, F. Cancani, F. Satta, T. Stoppa, F. Genuini, L. Zampini, G. Perdichizzi, S. Bottari, G. Fischer, M. Gawronski, O. Bonetti, A. Piermarini, I. Recchiuti, V. Leone, P. Rossi, A. Tabarini, P. Biasucci, D. Villani, A. Raponi Front Pediatr 2021

benzodiazepine (BDZ)
bundle
delirium
early mobilization
pediatric intensive care
sedation

Outcomes of a Delirium Prevention Program in Older Persons After Elective Surgery: A Stepped-Wedge Cluster Randomized Clinical Trial Deeken, F. Sánchez, A. Rapp, M. A. Denkinger, M. Brefka, S. Spank, J. Bruns, C. von Arnim, C. A. F. Küster, O. C. Conzelmann, L. O. Metz, B. R. Maurer, C. Skrobik, Y. Forkavets, O. Eschweiler, G. W. Thomas, C. JAMA Surg 2021
Advanced Age Is Associated With Catatonia in Critical Illness: Results From the Delirium and Catatonia Prospective Cohort Investigation Connell, J. Kim, A. Brummel, N. E. Patel, M. B. Vandekar, S. N. Pandharipande, P. Dittus, R. S. Heckers, S. Ely, E. W. Wilson, J. E. Front Psychiatry 2021

age
catatonia
coma
critical illness
delirium
or financial relationships that could be construed as a potential conflict of
interest.

Identifying frequent drug combinations associated with delirium in older adults: Application of association rules method to a case-time-control design Chyou, T. Y. Nishtala, P. S. Pharmacoepidemiol Drug Saf 2021

Aged
Aged, 80 and over
*Delirium/chemically induced/diagnosis/epidemiology
Drug Combinations
Humans
New Zealand
*association rules
*case-time-control design
*delirium
*older people
*pharmacoepidemiology
*pharmacovigilance

Risk Factors and a Nomogram Model Establishment for Postoperative Delirium in Elderly Patients Undergoing Arthroplasty Surgery: A Single-Center Retrospective Study Chen, D. Li, Y. Li, Q. Gao, W. Li, J. Wang, S. Cao, J. Biomed Res Int 2021
Detecting Incident Delirium within Routinely Collected Inpatient Rehabilitation Data: Validation of a Chart-Based Method Ceppi, M. G. Rauch, M. S. Sándor, P. S. Gantenbein, A. R. Krishnakumar, S. Albert, M. Meier, C. R. Neurol Int 2021

delirium
neurocognitive disorders
patient-generated health data
rehabilitation
validation study

Spinal Anesthesia with Targeted Sedation based on Bispectral Index Values Compared with General Anesthesia with Masked Bispectral Index Values to Reduce Delirium: The SHARP Randomized Controlled Trial Brown, C. H. Edwards, C. Lin, C. Jones, E. L. Yanek, L. R. Esmaili, M. Gorashi, Y. Skelton, R. Kaganov, D. Curto, R. Lessing, N. L. Cha, S. Colantuoni, E. Neufeld, K. Sieber, F. Dean, C. L. Hogue, C. W. Anesthesiology 2021

Aged
Anesthesia, General/adverse effects/*methods
Anesthesia, Spinal/adverse effects/*methods
Electroencephalography/*methods
Emergence Delirium/*diagnosis/*physiopathology/prevention & control
Female
Humans
Male
Single-Blind Method

Delirium in Cardiac and Cardiovascular Surgical Intensive Care Units Breit, H. Bleck, T. P. Koffman, L. Semin Neurol 2021

Critical Care
*Delirium/diagnosis/etiology/therapy
Humans
Intensive Care Units

Are treatment effects consistent with hypothesized mechanisms of action proposed for postoperative delirium interventions? Reanalysis of systematic reviews Boxell, E. G. Malik, Y. Wong, J. Lee, M. H. Berntsson, H. M. Lee, M. J. Bourne, R. S. McCullagh, I. J. Hind, D. Wilson, M. J. J Comp Eff Res 2021

*Delirium/prevention & control
Humans
*Postoperative Complications
Systematic Reviews as Topic
*aging health
*meta-analysis
*methodology
*surgery

DelIrium VULnerability in GEriatrics (DIVULGE) study: a protocol for a prospective observational study of electroencephalogram associations with incident postoperative delirium Boord, M. S. Davis, D. H. J. Psaltis, P. J. Coussens, S. W. Feuerriegel, D. Garrido, M. I. Bourke, A. Keage, H. A. D BMJ Neurol Open 2021

Eeg
cognitive electrophysiology
event-related potentials
geriatrics
neurophysiology

Patient Factors That Influence Reliable Delirium Assessments in a Medical Intensive Care Unit During the Routine Clinical Practice Back, J. S. Jin, T. Jin, H. Lee, S. M. Clin Nurs Res 2021

Cam-icu
delirium
electronic health records
intensive care units
validation study

Monitoring Delirium in the Intensive Care Unit Practices, perceptions and attitudes of critical care nurses and physicians. A French National Survey Alaterre, C. Fazilleau, C. Constantin, J. M. James, A. Intensive Crit Care Nurs 2021

Critical Care
Critical care nurse
Delirium
Delirium monitoring
Intensive Care Unit
Medical Staff
Practices

Predictors of postoperative delirium in elderly patients following total hip and knee arthroplasty: a systematic review and meta-analysis Zhou, Q. Zhou, X. Zhang, Y. Hou, M. Tian, X. Yang, H. He, F. Chen, X. Liu, T. BMC Musculoskelet Disord 2021

Aged
*Arthroplasty, Replacement, Hip/adverse effects
*Arthroplasty, Replacement, Knee/adverse effects
*Delirium/diagnosis/epidemiology/etiology
Humans
Odds Ratio
Postoperative Complications/diagnosis/epidemiology/etiology
Risk Factors
Postoperative delirium
Predictors
Total hip arthroplasty
Total joint arthroplasty
Total knee arthroplasty

Incidence, characteristics, and outcomes of delirium in patients with noninvasive ventilation: a prospective observational study Zhang, R. Bai, L. Han, X. Huang, S. Zhou, L. Duan, J. BMC Pulm Med 2021

Aged
Aged, 80 and over
Critical Illness
Delirium/*epidemiology
Female
*Hospital Mortality
Hospitals, Teaching
Humans
Incidence
*Intensive Care Units
Logistic Models
Male
Middle Aged
Multivariate Analysis
Noninvasive Ventilation/*adverse effects
Prospective Studies
Risk Factors
Treatment Failure
Delirium
Noninvasive ventilation
Risk factor

A systematic review and meta-analysis of the correlation between operation time and postoperative delirium in total hip arthroplasty Zhang, G. Wang, Z. Wang, D. Jia, Q. Zeng, Y. Ann Palliat Med 2021

*Arthroplasty, Replacement, Hip/adverse effects
Case-Control Studies
*Delirium/etiology
Humans
Postoperative Complications/etiology
Retrospective Studies
*Total hip arthroplasty (THA)
*delirium
*meta-analysis
*operation time

The PREvention Program for Alzheimer's RElated Delirium (PREPARED) cluster randomized trial: a study protocol Wilchesky, M. Ballard, S. A. Voyer, P. McCusker, J. Lungu, O. Champoux, N. Vu, T. T. M. Cole, M. G. Monette, J. Ciampi, A. Belzile, E. Carmichael, P. H. McConnell, T. BMC Geriatr 2021

Aged
*Alzheimer Disease
*Delirium/diagnosis/epidemiology/prevention & control
Frail Elderly
Homes for the Aged
Humans
Randomized Controlled Trials as Topic
Retrospective Studies
*Delirium
*Delirium superimposed on dementia
*Long-term care
*Modifiable risk factors
*Multicomponent intervention
*Nursing

Anaesthetic depth and delirium: a challenging balancing act Whitlock, E. L. Gross, E. R. King, C. R. Avidan, M. S. Br J Anaesth 2021

Anesthesia, General
*Anesthesiology
*Anesthetics/adverse effects
*Delirium/epidemiology
Humans
*anaesthetic sensitivity
*bispectral index
*delirium
*depth of anaesthesia
*precision medicine

Identification of risk factors for postoperative delirium in elderly patients with hip fractures by a risk stratification index model: A retrospective study Wang, Y. Zhao, L. Zhang, C. An, Q. Guo, Q. Geng, J. Guo, Z. Guan, Z. Brain Behav 2021

health services for the elderly
hip fractures
postoperative cognitive complications
risk assessment
risk factors

Association between perioperative hypotension and postoperative delirium and atrial fibrillation after cardiac surgery: A post-hoc analysis of the DECADE trial Wang, J. Mao, G. Malackany, N. Marciniak, D. Donaldson, C. Wakefield, B. Hassan, M. Ruetzler, K. Sessler, D. I. Turan, A. J Clin Anesth 2021

Anesthesia
Atrial fibrillation
Delirium
Hypotension

The effect of the anticholinergic burden on duration and severity of delirium in older hip-surgery patients with and without haloperidol prophylaxis: A post hoc analysis Tillemans, M. P. H. Butterhoff-Terlingen, M. H. Stuffken, R. Vreeswijk, R. Egberts, T. C. G. Kalisvaart, K. J. Brain Behav 2021

anticholinergic burden
delirium
haloperidol
prophylaxis

Refractory hyperactive delirium in the dying: pharmacological management Tham, K. Shiu, A. William, L. Walpole, G. Rashed, S. BMJ Support Palliat Care 2021

delirium
pharmacology
symptoms and symptom management
terminal care

Time to Post-Anesthesia Neurological Evaluation and Hemodynamic Stability in Carotid Endarterectomy Comparing Three General Anesthetic Techniques Targeted to a Preset Bispectral Index Value: A Pilot Study Temmermand, R. Mitrev, L. van Helmond, N. Roberts, D. Lombardi, J. Vuckovic, D. Aana j 2021

Anesthesia, General
*Anesthetics, General/pharmacology
Anesthetics, Intravenous
*Endarterectomy, Carotid
Hemodynamics/drug effects
Humans
Pilot Projects
Piperidines/pharmacology
*Propofol
Prospective Studies
Carotid endarterectomy
general anesthesia
intraoperative stroke
postoperative cognitive dysfunction
postoperative delirium

Delirium During Acute Events in Nursing Home Patients Skretteberg, W. H. Holmefoss, I. Krogseth, M. J Am Med Dir Assoc 2021

Delirium
acute disease
benzodiazepines
nursing home

The impact of emergence delirium on hospital length of stay for children who underwent tonsillectomy/adenotonsillectomy: an observational retrospective study Simonini, A. Vittori, A. Cascella, M. Calevo, M. G. Marinangeli, F. Braz J Anesthesiol 2021

Anesthesia
Children
Dexmedetomidine
Emergence delirium
Length of stay
Pain

Effects of Melatonin on Postoperative Delirium After PCI in Elderly Patients: A Randomized, Single-Center, Double-Blind, Placebo-Controlled Trial Shi, Y. Heart Surg Forum 2021

Effects of Melatonin

Postoperative Delirium

PCI

Elderly Patients

Randomized

Single-Center

Double-Blind

Placebo-Controlled Trial

A Quality Improvement Initiative to Reduce Postoperative Delirium among Cardiac Surgery Patients Sanjanwala, R. M. Hiebert, B. Kent, D. Warren, S. Grocott, H. Arora, R. C. Geriatrics (Basel) 2021

cardiac surgery
care strategies
postoperative care
postoperative delirium
quality improvement

The prevalence of delirium in belgian nursing homes: a cross-sectional evaluation Sabbe, K. van der Mast, R. Dilles, T. Van Rompaey, B. BMC Geriatr 2021

Aged
Aged, 80 and over
Belgium/epidemiology
Cross-Sectional Studies
*Delirium/diagnosis/epidemiology
Female
Humans
Nursing Homes
Prevalence
*Delirium
*delirium point-prevalence
*delirium screening
*long-term care
*nursing homes
*precipitating delirium factors

Family intervention for delirium for patients in the intensive care unit: A systematic meta-analysis Qin, M. Gao, Y. Guo, S. Lu, X. Zhu, H. Li, Y. J Clin Neurosci 2021

Delirium
Family engagement
Family intervention
ICU

Orthogeriatric co-management reduces incidence of delirium in hip fracture patients Pollmann, C. T. Mellingsæter, M. R. Neerland, B. E. Straume-Næsheim, T. Årøen, A. Watne, L. O. Osteoporos Int 2021

*Delirium/epidemiology/etiology/prevention & control
*Hip Fractures/epidemiology
Humans
Incidence
Logistic Models
Prospective Studies
Delirium
Hip fracture
Orthogeriatric co-management
Subsyndromal delirium

Accuracy of delirium assessments in critically ill children: A prospective, observational study during routine care Paterson, R. S. Kenardy, J. A. Dow, B. L. De Young, A. C. Pearson, K. Aitken, L. M. Long, D. A. Aust Crit Care 2021

Australia
Child
Child, Preschool
*Critical Illness
*Delirium/diagnosis
Humans
Intensive Care Units
Intensive Care Units, Pediatric
Prospective Studies
*Delirium
*Intensive care units
*Paediatric
*Psychometrics
*Screening
interest to disclose.

Comparative effectiveness of pharmacological interventions to prevent postoperative delirium: a network meta-analysis Park, S. K. Lim, T. Cho, H. Yoon, H. K. Lee, H. J. Lee, J. H. Yoo, S. Kim, J. T. Kim, W. H. Sci Rep 2021

Adult
Antipsychotic Agents/administration & dosage
*Bayes Theorem
Delirium/etiology/*prevention & control
Haloperidol/administration & dosage
Humans
Network Meta-Analysis
Pharmaceutical Preparations/*administration & dosage/classification
Postoperative Complications/etiology/*prevention & control
Randomized Controlled Trials as Topic
Treatment Outcome

Dexmedetomidine, Delirium, and Adverse Outcomes: Analysis of the Society of Thoracic Surgeons Adult Cardiac Surgery Database Pal, N. Abernathy, J. H., 3rd Taylor, M. A. Bollen, B. A. Shah, A. S. Feng, X. Shotwell, M. S. Kertai, M. D. Ann Thorac Surg 2021

Analgesics, Non-Narcotic/adverse effects
Cardiac Surgical Procedures/*adverse effects
Delirium/*epidemiology/etiology
Dexmedetomidine/*adverse effects
Humans
Incidence
Pain, Postoperative/prevention & control
Postoperative Complications/*epidemiology/etiology
*Propensity Score
Retrospective Studies
Societies, Medical/*statistics & numerical data
Thoracic Surgery/*statistics & numerical data
United States/epidemiology

ICU delirium burden predicts functional neurologic outcomes Paixao, L. Sun, H. Hogan, J. Hartnack, K. Westmeijer, M. Neelagiri, A. Zhou, D. W. McClain, L. M. Kimchi, E. Y. Purdon, P. L. Akeju, O. Westover, M. B. PLoS One 2021

ICU delirium

functional neurologic

outcomes

Delirium occurrence and association with outcomes in hospitalized COVID-19 patients Pagali, S. Fu, S. Lindroth, H. Sohn, S. Burton, M. C. Lapid, M. Int Psychogeriatr 2021

Adolescent
Adult
Aged
Aged, 80 and over
COVID-19/complications/*mortality
Child
Child, Preschool
Delirium/complications/*epidemiology
Hospitalization/*statistics & numerical data
Humans
Infant
Infant, Newborn
Intensive Care Units
Length of Stay
Male
Middle Aged
Minnesota/epidemiology
Retrospective Studies
SARS-CoV-2
Young Adult
*COVID-19 severity
*delirium
*hospitalized COVID-19
*outcomes

Risk Factors for Delirium in Older Adults in the Emergency Department: A Systematic Review and Meta-Analysis Oliveira, J. E. Silva L. Berning, M. J. Stanich, J. A. Gerberi, D. J. Murad, M. H. Han, J. H. Bellolio, F. Ann Emerg Med 2021

Aged
Aged, 80 and over
Delirium/*prevention & control
*Emergency Service, Hospital
Geriatric Assessment/*methods
Humans
Risk Assessment
Risk Factors

Factors associated with delirium among survivors of acute respiratory distress syndrome: a nationwide cohort study Oh, T. K. Park, H. Y. Song, I. A. BMC Pulm Med 2021

Critical Care
Delirium
Mortality
Respiratory distress syndrome

Rapid Handheld Continuous Electroencephalogram (EEG) Has the Potential to Detect Delirium in Older Adults Mulkey, M. A. Gantt, L. T. Hardin, S. R. Munro, C. L. Everhart, D. E. Kim, S. Schoeman, A. M. Roberson, D. W. McAuliffe, M. Olson, D. M. Dimens Crit Care Nurs 2021

Aged
Critical Illness
*Delirium/diagnosis
Electroencephalography
Humans
Pilot Projects
Prospective Studies

Delirium and Clusters of Older Patients Affected by Multimorbidity in Acute Hospitals Monacelli, F. Signori, A. Marengoni, A. Di Santo, S. Rossi, E. Valsecchi, M. G. Morandi, A. Bellelli, G. J Am Med Dir Assoc 2021

Delirium
multimorbidity

Major Surgery and Long Term Cognitive Outcomes: The Effect of Postoperative Delirium on Dementia in the Year Following Discharge Mohanty, S. Gillio, A. Lindroth, H. Ortiz, D. Holler, E. Azar, J. Boustani, M. Zarzaur, B. J Surg Res 2021

Dementia
Geriatrics
Postoperative delirium
Surgery

Elevated neuron-specific enolase level is associated with postoperative delirium and detection of phosphorylated neurofilament heavy subunit: A prospective observational study Mietani, K. Hasegawa-Moriyama, M. Inoue, R. Ogata, T. Shimojo, N. Kurano, M. Sumitani, M. Uchida, K. PLoS One 2021

Elevated neuron-specific enolase level

postoperative delirium

phosphorylated neurofilament heavy subunit

prospective observational study

Variations in analgesic, sedation, and delirium management between trauma and non-trauma critically ill children Mehl, S. C. Cunningham, M. E. Chance, M. D. Zhu, H. Fallon, S. C. Naik-Mathuria, B. Ettinger, N. A. Vogel, A. M. Pediatr Surg Int 2021

Analgesia
Children
Critically ill
Delirium
Sedation
Trauma

Simulation Training Exercise to Improve Outcomes of Emergence Delirium in Patients With Posttraumatic Stress Disorder Lovestrand, D. Beaumont, C. D. Calder, M. S. Schmidt, M. Calaro, R. Aana j 2021

Anesthesia
*Emergence Delirium
Humans
Military Personnel
*Simulation Training
*Stress Disorders, Post-Traumatic
Emergence delirium
perianesthesia
perioperative education
posttraumatic stress disorder
simulation

Effects of Glucocorticoids on Postoperative Delirium in Adult Patients Undergoing Cardiac Surgery: A Systematic Review and Meta-analysis Liu, W. Wang, Y. Wang, J. Shi, J. Pan, J. Wang, D. Clin Ther 2021

Glucocorticoids

Postoperative Delirium

Adult

Cardiac Surgery

A Systematic Review

Meta-analysis

The Association Between Preoperative Frailty and Postoperative Delirium: A Systematic Review and Meta-analysis Liu, C. Y. Gong, N. Liu, W. J Perianesth Nurs 2021

delirium
frailty
meta-analysis
perioperative period

A complex intervention to promote prevention of delirium in older adults by targeting caregiver's participation during and after hospital discharge - study protocol of the TRAnsport and DElirium in older people (TRADE) project Leinert, C. Brefka, S. Braisch, U. Denninger, N. Mueller, M. Benzinger, P. Bauer, J. Bahrmann, A. Frey, N. Katus, H. A. Geisler, T. Eschweiler, G. Klaus, J. Seufferlein, T. Schuetze, K. Gebhard, F. Dreyhaupt, J. Muche, R. Pahmeier, K. Biermann-Stallwitz, BMC Geriatr 2021

Aged
Caregivers
*Delirium/diagnosis/epidemiology/prevention & control
Hospitals
Humans
Multicenter Studies as Topic
*Patient Discharge
Pilot Projects
Prospective Studies
Systematic Reviews as Topic
*Caregiver
*Complex intervention
*Delirium
*Dementia
*Discharge
*Family
*Geriatrics
*Older adults
*Transfer
*Transport

Evaluation of Bedside Tests of Attention and Arousal Assessing Delirium in Parkinson's Disease, Dementia, and Older Adults Lawson, R. A. Richardson, S. J. Kershaw, D. Davis, D. Stephan, B. C. M. Robinson, L. Brayne, C. Barnes, L. Burn, D. J. Yarnall, A. J. Taylor, J. P. Parker, S. Allan, L. M. J Parkinsons Dis 2021

Delirium
Parkinson disease
arousal
attention
dementia
diganosis

Dexmedetomidine and paralytic exposure after damage control laparotomy: risk factors for delirium? Results from the EAST SLEEP-TIME multicenter trial Krause, C. Kwon, E. Luo-Owen, X. McArthur, K. Cochran-Yu, M. Swentek, L. Burruss, S. Turay, D. Grigorian, A. Nahmias, J. Butt, A. Gutierrez, A. LaRiccia, A. Kincaid, M. Fiorentino, M. N. Glass, N. Toscano, S. Ley, E. Lombardo, S. R. Guillamondegui, O. D. Eur J Trauma Emerg Surg 2021

Damage control laparotomy
Delirium
Non-trauma
Sedation
Trauma


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