Delirium Bibliography

The searchable delirium bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons.  The NIDUS team keeps it updated for you on a monthly basis!  Feel free to search by author, title, year, keywords. It is primarily intended for clinicians and researchers interested in exploring these topics.

To retrieve full information, click on the title of the article and scroll down to read the abstract, journal, etc.

Each article is indexed by keywords taken from MEDLINE and other relevant databases.

You may base your search on as many search terms as you like. A search term can be a keyword, an author’s name, all or part of an article’s title, or the year of publication.

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Total Records Found: 4273, showing 100 per page
TitleAuthorsJournalYearKeywords
Spinal block and delirium in oncologic patients after laparoscopic surgery in the Trendelenburg position: A randomized controlled trial Mitsunaga, J. K. Junior Calsavara, V. F. Onari, E. S. Arantes, V. M. Akamine, C. P. Handa, A. M. Quezada, M. M. C. Ito, F. Y. Porto, A. C. S. Giroud Joaquim, E. H. Nakamura, G. PLoS One 2021
Perioperative Vascular Biomarker Profiling in Elective Surgery Patients Developing Postoperative Delirium: A Prospective Cohort Study Menzenbach, J. Frede, S. Petras, J. Guttenthaler, V. Kirfel, A. Neumann, C. Mayr, A. Wittmann, M. Coburn, M. Klaschik, S. Hilbert, T. Biomedicines 2021

Ccl2
Mcp-1
biomarker
cardiac surgery
elective surgery
glycocalyx
postoperative delirium
vascular inflammation

Preliminary Study of Serum Biomarkers Associated With Delirium After Major Cardiac Surgery McKay, T. B. Rhee, J. Colon, K. Adelsberger, K. Turco, I. Mueller, A. Qu, J. Akeju, O. J Cardiothorac Vasc Anesth 2021

Fgf
cardiac surgery
cardiopulmonary bypass
cognition
delirium
fibroblast growth factor
inflammation
metabolism
neurodegeneration

Stratified delirium risk using prescription medication data in a state-wide cohort McCoy, T. H., Jr. Castro, V. M. Hart, K. L. Perlis, R. H. Gen Hosp Psychiatry 2021

Cohort study
Data mining
Delirium
Feature engineering
Pharmacovigilance
Predictive modeling

Nutritional Risk at intensive care unit admission and outcomes in survivors of critical illness Mart, M. F. Girard, T. D. Thompson, J. L. Whitten-Vile, H. Raman, R. Pandharipande, P. P. Heyland, D. K. Ely, E. W. Brummel, N. E. Clin Nutr 2021

Activities of daily living
Cognitive dysfunction
Critical illness
Nutrition assessment
Patient discharge
Quality of life

Risk Factors for Delirium Are Different in the Very Old: A Comparative One-Year Prospective Cohort Study of 5,831 Patients Marquetand, J. Bode, L. Fuchs, S. Hildenbrand, F. Ernst, J. von Kaenel, R. Boettger, S. Front Psychiatry 2021

comparison
delirium
prospective
risk factors
very old

Plasma interleukin-6 is a potential predictive biomarker for postoperative delirium among acute type a aortic dissection patients treated with open surgical repair Lv, X. C. Lin, Y. Wu, Q. S. Wang, L. Hou, Y. T. Dong, Y. Chen, L. W. J Cardiothorac Surg 2021

Adult
Aged
Aneurysm, Dissecting/ surgery
Aortic Aneurysm/ surgery
Area Under Curve
Biomarkers/blood
Delirium/ blood/etiology
Humans
Interleukin-6/ blood
Male
Middle Aged
Postoperative Complications/blood/etiology
ROC Curve
Retrospective Studies
Aortic dissection
Inflammatory cytokines
Interleukin-6
Postoperative delirium

Association of early and later depressive symptoms with functional outcome after ischemic stroke Lopatkiewicz, A. M. Pera, J. Slowik, A. Dziedzic, T. J Neural Transm (Vienna) 2021

Cognitive decline
Delirium
Depression
Outcome
Stroke

Development and validation of a postoperative delirium prediction model for pediatric patients: A prospective, observational, single-center study Lin, N. Liu, K. Feng, J. Chen, R. Ying, Y. Lv, D. Zhou, Y. Xu, H. Medicine (Baltimore) 2021

Adolescent
Anesthesia, General/ adverse effects/methods
Child
Child, Preschool
Developmental Disabilities/ epidemiology
Dexmedetomidine/administration & dosage/ adverse effects
Emergence Delirium/ epidemiology/etiology/prevention & control
Female
Humans
Hypnotics and Sedatives/administration & dosage/ adverse effects
Infant
Infant, Newborn
Logistic Models
Male
Prevalence
Prospective Studies
ROC Curve
Risk Assessment/methods/statistics & numerical data
Risk Factors

Patients' experiences of delirium: A systematic review and meta-summary of qualitative research Kuusisto-Gussmann, E. Höckelmann, C. von der Lühe, V. Schmädig, R. Baltes, M. Stephan, A. J Adv Nurs 2021

delirium
nursing
qualitative research
systematic review

Effects of case-based confusion assessment methods for intensive care unit training on delirium knowledge and delirium assessment accuracy of intensive care units: A quasi-experimental study Kim, Y. N. Kim, D. H. Nurse Educ Today 2021

Critical Illness
Delirium/diagnosis
Hospitals, University
Humans
Intensive Care Units
Republic of Korea
Assessment
Delirium
Education
Intensive care unit
Knowledge
Nursing

Bridging the Gap Between the Intensive Care Unit and the Acute Medical Care Unit Kim, E. Kast, C. Afroz-Hossain, A. Qiu, M. Pappas, K. Sinvani, L. Am J Crit Care 2021
Preoperative MRI brain phenotypes are related to postoperative delirium in older individuals Kant, I. M. J. Slooter, A. J. C. Jaarsma-Coes, M. van Montfort, S. J. T. Witkamp, T. D. Pasma, W. Hendrikse, J. de Bresser, J. Neurobiol Aging 2021

Brain phenotypes
Delirium
Encephalopathy
Mri

Pre-Existing Psychiatric Illness Is Associated With an Increased Risk of Delirium in Patients With Acute Respiratory Distress Syndrome Kalra, S. S. Jaber, J. Alzghoul, B. N. Hyde, R. Parikh, S. Urbine, D. Reddy, R. J Intensive Care Med 2021

Ards
acute respiratory distress syndrome
anxiety
delirium
depression
psychiatric illness

Development and internal validation of a predictive model of cognitive decline 36 months following elective surgery Jones, R. N. Tommet, D. Steingrimsson, J. Racine, A. M. Fong, T. G. Gou, Y. Hshieh, T. T. Metzger, E. D. Schmitt, E. M. Tabloski, P. A. Travison, T. G. Vasunilashorn, S. M. Abdeen, A. Earp, B. Kunze, L. Lange, J. Vlassakov, K. Dickerson, B. C. Marcantonio Alzheimers Dement (Amst) 2021

cognitive decline
delirium
machine learning
model prediction
post‐operative
statistical learning

The performance of the Dutch Safety Management System frailty tool to predict the risk of readmission or mortality in older hospitalised cardiac patients Jepma, P. Verweij, L. Tijssen, A. Heymans, M. W. Flierman, I. Latour, C. H. M. Peters, R. J. G. Scholte Op Reimer, W. J. M. Buurman, B. M. Ter Riet, G. BMC Geriatr 2021

Aged
Aged, 80 and over
Female
Frailty
Geriatric Assessment
Humans
Male
Netherlands/epidemiology
Patient Readmission
Prospective Studies
Risk Assessment
Risk Factors
Safety Management
Cardiovascular diseases
Mortality
Predictive value of tests

Outcomes of transcatheter aortic valve replacement in patients with cognitive dysfunction Jain, V. Kalra, A. Panhwar, M. S. Bansal, A. Nowacki, A. Bhatia, K. Gupta, T. Ineman, N. L. Khan, S. U. Krishnaswamy, A. Reed, G. W. Puri, R. Kapadia, S. R. Svensson, L. G. Kanaa, N. A. Lahorra, J. A. J Am Geriatr Soc 2021

cognitive impairment
dementia
outcomes
transcatheter aortic valve replacement

The Importance of Delirium and Delirium Prevention in Older Adults During Lockdowns Inouye, S. K. JAMA 2021

Aged
COVID-19/ psychology
Delirium/etiology/ prevention & control
Hospitalization
Humans
Infection Control
Inpatients/psychology
Physical Distancing

Association of Pain With Atrial Fibrillation and Delirium After Cardiac Surgery: A DECADE Sub-Study Ince, I. Chiu, A. Sagir, A. Chahar, P. Lin, J. Douglas, A. Adi, A. Fang, J. Mao, G. Turan, A. J Cardiothorac Vasc Anesth 2021

atrial fibrillation
delirium
pain

Higher versus lower mean arterial pressure target management in older patients having non-cardiothoracic surgery: A prospective randomized controlled trial Hu, A. M. Qiu, Y. Zhang, P. Zhao, R. Li, S. T. Zhang, Y. X. Zheng, Z. H. Hu, B. L. Yang, Y. L. Zhang, Z. J. J Clin Anesth 2021

Aged
Anesthesia, General/adverse effects
Arterial Pressure
Delirium/epidemiology/etiology/prevention & control
Female
Humans
Postoperative Complications/epidemiology/etiology/prevention & control
Prospective Studies
Elderly patients
General anaesthesia
Mean arterial pressure
Postoperative delirium

Are Patients Taking Benzodiazepines at Increased Risk for Complications Following Primary Total Knee Arthroplasty? Hernandez, N. M. Cunningham, D. J. Hinton, Z. W. Wu, C. J. Seyler, T. M. J Arthroplasty 2021

Arthroplasty, Replacement, Knee/adverse effects
Benzodiazepines/adverse effects
Humans
Joint Diseases
Odds Ratio
Postoperative Complications/chemically induced/epidemiology
Reoperation
Retrospective Studies
Risk Factors
benzodiazepines
complications
delirium
revision
total knee arthroplasty

Preoperative medication use and development of postoperative delirium and cognitive dysfunction Heinrich, M. Nottbrock, A. Borchers, F. Mörgeli, R. Kruppa, J. Winterer, G. Slooter, A. J. C. Spies, C. Clin Transl Sci 2021
Radiological, Chemical, and Pharmacological Cholinergic System Parameters and Neurocognitive Disorders in Older Presurgical Adults Heinrich, M. Müller, A. Lammers-Lietz, F. Borchers, F. Mörgeli, R. Kruppa, J. Zacharias, N. Winterer, G. Slooter, A. J. C. Spies, C. D. J Gerontol A Biol Sci Med Sci 2021

Anticholinergic medication
Cholinesterase
Cognition
Magnetic resonance imaging

Predictors and Sequelae of Postoperative Delirium in a Geriatric Patient Population With Hip Fracture Haynes, M. S. Alder, K. D. Toombs, C. Amakiri, I. C. Rubin, L. E. Grauer, J. N J Am Acad Orthop Surg Glob Res Rev 2021
Visual Analytics in Delirium Management Hackl, W. O. Netzer, M. Nantschev, R. Schaller, M. Ammenwerth, E. Stud Health Technol Inform 2021

Aged
Cluster Analysis
Data Mining
Delirium
Humans
Delirium management
data visualization
patient safety

Characterizing Sleep Disruption and Delirium in Children After Cardiac Surgery: A Feasibility Study Gregory, J. L. Brown, A. T. Kudchadkar, S. R. Pediatr Crit Care Med 2021
One-Year Medicare Costs Associated With Delirium in Older Patients Undergoing Major Elective Surgery Gou, R. Y. Hshieh, T. T. Marcantonio, E. R. Cooper, Z. Jones, R. N. Travison, T. G. Fong, T. G. Abdeen, A. Lange, J. Earp, B. Schmitt, E. M. Leslie, D. L. Inouye, S. K. JAMA Surg 2021
Implementing Delirium Screening in an Intermediate Care Unit Gaa, C. A. Akintade, B. F. J Dr Nurs Pract 2021

confusion assessment method
delirium
delirium screening
intermediate care unit

Malocclusion of Molar Teeth Is Associated with Activities of Daily Living Loss and Delirium in Elderly Critically Ill Older Patients Fujinami, Y. Hifumi, T. Ono, Y. Saito, M. Okazaki, T. Shinohara, N. Akiyama, K. Kunikata, M. Inoue, S. Kotani, J. Kuroda, Y. J Clin Med 2021

ICU prognosis
frailty
poor oral health

Electroencephalography of mechanically ventilated patients at high risk of delirium Eskioglou, E. Iaquaniello, C. Alvarez, V. Rüegg, S. Schindler, K. Rossetti, A. O. Oddo, M. Acta Neurol Scand 2021

Eeg
critical care
delirium

Risk Factors and Antipsychotic Usage Patterns Associated With Terminal Delirium in a Veteran Long-Term Care Hospice Population Ellsworth, E. M. Bacigalupo, K. J. Palla, K. R. Limaye, S. S. Walkosz, M. J. Szczecinski, S. T. Suda, K. J. Fed Pract 2021
Does cognitive decline/dementia increase Delirium risk after stroke? Ding, G. Hua, S. Chen, J. Yang, S. Xie, R. Psychogeriatrics 2021

Cognitive Dysfunction
Delirium
Dementia
Humans
Odds Ratio
Stroke
cognitive decline
meta-analysis
stroke.

Heterogeneity in design and analysis of ICU delirium randomized trials: a systematic review Colantuoni, E. Koneru, M. Akhlaghi, N. Li, X. Hashem, M. D. Dinglas, V. D. Neufeld, K. J. Harhay, M. O. Needham, D. M. Trials 2021

Adult
Critical Illness
Delirium/diagnosis/prevention & control
Humans
Intensive Care Units
Randomized Controlled Trials as Topic
Critically ill patients
Delirium
Outcome definition
Randomized trials
Statistical methods
Systematic review

The frequency and quality of delirium documentation in discharge summaries Chuen, V. L. Chan, A. C. H. Ma, J. Alibhai, S. M. H. Chau, V. BMC Geriatr 2021

Delirium/diagnosis/epidemiology
Documentation
Hospitalization
Humans
Patient Discharge
Retrospective Studies
Delirium
Discharge summary
Geriatrics
Quality

Using data linkage for national surveillance of clinical quality indicators for dementia care among Australian aged care users Cations, M. Lang, C. Ward, S. A. Caughey, G. E. Crotty, M. Whitehead, C. Ahern, S. Maddison, J. Inacio, M. C. Sci Rep 2021
Geriatric fracture centre vs usual care after proximal femur fracture in older patients: what are the benefits? Results of a large international prospective multicentre study Blauth, M. Joeris, A. Rometsch, E. Espinoza-Rebmann, K. Wattanapanom, P. Jarayabhand, R. Poeze, M. Wong, M. K. Kwek, E. B. K. Hegeman, J. H. Perez-Uribarri, C. Guerado, E. Revak, T. J. Zohner, S. Joseph, D. Gosch, M. BMJ Open 2021

Aged
Aged, 80 and over
Cohort Studies
Femur
Hip Fractures/surgery
Humans
Prospective Studies
Quality of Life
geriatric medicine
health services administration & management
hip
orthopaedic & trauma surgery
trauma management

Effects of dexmedetomidine on neurocognitive disturbance after elective non-cardiac surgery in senile patients: a systematic review and meta-analysis Bi, X. Wei, J. Zhang, X. J Int Med Res 2021

China
Cognitive Dysfunction/drug therapy/prevention & control
Delirium
Dexmedetomidine/therapeutic use
Humans
Hypotension
Postoperative Complications/prevention & control
Anesthesiology
dexmedetomidine
non-cardiac surgery
postoperative cognitive disturbance
postoperative delirium
senile

Non-pharmacological interventions for preventing delirium in hospitalised non-ICU patients (Review) Burton JK, Craig LE, Yong SQ, Siddiqi N, Teale EA, Woodhouse R, Barugh AJ, Shepherd AM, Brunton A, Freeman SC, Sutton AJ, Quinn TJ Cochrane Database of Systematic Reviews 2021
Incidence and risk factors for postoperative delirium after liver transplantation: a systematic review and meta-analysis Zhou, S. Deng, F. Zhang, J. Chen, G. Eur Rev Med Pharmacol Sci 2021
The perioperative application of continuous cerebral autoregulation monitoring for cerebral protection in elderly patients Zhang, Y. Tan, J. Li, P. Zhang, X. Yang, Y. Liu, Y. Fu, Q. Cao, J. Mi, W. Zhang, H. Li, H. Ann Palliat Med 2021

Aged
Arterial Pressure
Cerebrovascular Circulation
Homeostasis
Humans
Male
Middle Aged
Oximetry
Spectroscopy, Near-Infrared
Cerebral autoregulation (CA)
optimal mean arterial pressure (optimal MAP)
regional cerebral oxygen saturation (rScO2)
robotic-assisted laparoscopic radical prostatectomy (RALP)

Prospective Randomized Controlled Pilot Study of High-Intensity Lightbox Phototherapy to Prevent ICU-Acquired Delirium Incidence Zhang, K. S. Pelleg, T. Hussain, S. Kollipara, V. Loschner, A. Foroozesh, M. B. Rubio, E. Biscardi, F. Ie, S. R. Cureus 2021

bright light therapy
circadian rhythm
delirium in icu
icu delirium
prolonged mechanical ventilation
quality improvement and patient safety

Neurocognitive disorders in the elderly: altered functional resting-state hyperconnectivities in postoperative delirium patients Winterer, J. M. Ofosu, K. Borchers, F. Hadzidiakos, D. Lammers-Lietz, F. Spies, C. Winterer, G. Zacharias, N. Transl Psychiatry 2021

Aged
Delirium
Humans
Magnetic Resonance Imaging
Prefrontal Cortex
Prospective Studies
Rest

Relationships between preoperative cortical thickness, postoperative electroencephalogram slowing, and postoperative delirium White, M. F. Tanabe, S. Casey, C. Parker, M. Bo, A. Kunkel, D. Nair, V. Pearce, R. A. Lennertz, R. Prabhakaran, V. Lindroth, H. Sanders, R. D. Br J Anaesth 2021

cortical slowing
cortical thickness
delirium
neurodegeneration
surgery

COVID-19 in adults with dementia: clinical features and risk factors of mortality-a clinical cohort study on 125 patients Vrillon, A. Mhanna, E. Aveneau, C. Lebozec, M. Grosset, L. Nankam, D. Albuquerque, F. Razou Feroldi, R. Maakaroun, B. Pissareva, I. Cherni Gherissi, D. Azuar, J. François, V. Hourrègue, C. Dumurgier, J. Volpe-Gillot, L. Paquet, C. Alzheimers Res Ther 2021

Aged, 80 and over
COVID-19/complications/ mortality
COVID-19 Testing
Comorbidity
Dementia/complications/virology
Female
France/epidemiology
Humans
Male
Prospective Studies
Risk Factors
Covid-19
Dementia
Mortality
Prognostic factors
SARS-CoV-2

Risk Factors for Delirium after Vascular Surgery: A Systematic Review and Meta-Analysis Visser, L. Prent, A. Banning, L. B. D. van Leeuwen, B. L. Zeebregts, C. J. Pol, R. A. Ann Vasc Surg 2021
Etiologies of Delirium in Consecutive COVID-19 Inpatients and the Relationship Between Severity of Delirium and COVID-19 in a Prospective Study With Follow-Up Velásquez-Tirado, J. D. Trzepacz, P. T. Franco, J. G. J Neuropsychiatry Clin Neurosci 2021

Covid-19
Delirium
Psychiatric Status Rating Scales
Severity of Illness Index

Increased Emergency Department Hallway Length of Stay is Associated with Development of Delirium van Loveren, K. Singla, A. Sinvani, L. Calandrella, C. Perera, T. Brave, M. Becker, L. Li, T. West J Emerg Med 2021

Adolescent
Adult
Aged
Case-Control Studies
Causality
Delirium/ epidemiology/physiopathology
Emergency Service, Hospital/ statistics & numerical data
Humans
Length of Stay
Logistic Models
Male
Middle Aged
Pilot Projects
Retrospective Studies
Time-to-Treatment

Delirium in Children Undergoing Hematopoietic Cell Transplantation: A Multi-Institutional Point Prevalence Study Traube, C. Gerber, L. M. Mauer, E. A. Small, K. Broglie, L. Chopra, Y. R. Duncan, C. N. Ebens, C. L. Fitzgerald, J. C. Freedman, J. L. Hudspeth, M. P. Hurley, C. Mahadeo, K. M. McArthur, J. Shapiro, M. C. Sharron, M. P. Wall, D. A. Zinter, M. S. Greenwald Front Oncol 2021

cancer
cornell assessment of pediatric delirium
delirium
hematopoietic cell transplant
incidence
pediatric oncology
risk factors

Agreement Between the Mini-Cog in the Preoperative Clinic and on the Day of Surgery and Association With Postanesthesia Care Unit Delirium: A Cohort Study of Cognitive Screening in Older Adults Tiwary, N. Treggiari, M. M. Yanez, N. D. Kirsch, J. R. Tekkali, P. Taylor, C. C. Schenning, K. J. Anesth Analg 2021

Aged
Aged, 80 and over
Anesthesia Recovery Period
Anesthesia, General/ adverse effects
Cognition
Cognitive Dysfunction/complications/ diagnosis/psychology
Elective Surgical Procedures/ adverse effects
Emergence Delirium/diagnosis/ etiology/psychology
Female
Humans
Male
Mental Status and Dementia Tests
Predictive Value of Tests
Preoperative Care
Reproducibility of Results
Risk Assessment
Risk Factors
Treatment Outcome

A qualitative analysis of clinicians' communication strategies with family members of patients experiencing hospital-acquired delirium Taylor, G. B. Radhakrishnan, N. Fisher, C. L. Price, C. Tighe, P. Le, T. Bylund, C. L. Geriatr Nurs 2021
A scalable approach for developing clinical risk prediction applications in different hospitals Sun, H. Depraetere, K. Meesseman, L. De Roo, J. Vanbiervliet, M. De Baerdemaeker, J. Muys, H. von Dossow, V. Hulde, N. Szymanowsky, R. J Biomed Inform 2021

Acute kidney injury
Clinical decision support
Delirium
Electronic health records (EHR)
Machine learning
Scalability
Sepsis

The Relative Impact of Specific Postoperative Complications on Older Patients Undergoing Hip Fracture Repair Stahl, C. C. Funk, L. M. Schumacher, J. R. Zarzaur, B. L. Scarborough, J. E. Jt Comm J Qual Patient Saf 2021
Brain MRI after critical care admission: A longitudinal imaging study Sprung, J. Warner, D. O. Knopman, D. S. Petersen, R. C. Mielke, M. M. Jack, C. R., Jr. Martin, D. P. Hanson, A. C. Schroeder, D. R. Przybelski, S. A. Schulte, P. J. Laporta, M. L. Weingarten, T. N. Vemuri, P. J Crit Care 2021

AD-signature cortex
Corpus callosum
Cortical thinning
Hippocampus
Intensive care unit
Magnetic resonance imaging
Older adults

Effect of age on dexmedetomidine treatment for ventilated patients with sepsis: a post-hoc analysis of the DESIRE trial Sato, T. Kawazoe, Y. Miyagawa, N. Yokokawa, Y. Kushimoto, S. Miyamoto, K. Ohta, Y. Morimoto, T. Yamamura, H. Acute Med Surg 2021

Delirium
dexmedetomidine
elderly
sedative effect
sepsis

Effects of comprehensive geriatric care models on postoperative outcomes in geriatric surgical patients: a systematic review and meta-analysis Saripella, A. Wasef, S. Nagappa, M. Riazi, S. Englesakis, M. Wong, J. Chung, F. BMC Anesthesiol 2021

Adverse outcomes
Comprehensive geriatric assessment
Comprehensive geriatric care model
Delirium
Elderly
Surgery
Long-Term Care

Influence of Age on Postoperative Neurological Outcomes after Surgery of Acute Type A Aortic Dissection Salem, M. Salib, M. Friedrich, C. Salem, M. Puehler, T. Schoettler, J. Schoeneich, F. Cremer, J. Haneya, A. J Clin Med 2021

acute type A aortic dissection
moderate hypothermic circulatory arrest
neurological complication in elderly after type A aortic dissection

Associations between caregiver-detected delirium and symptoms of depression and anxiety in family caregivers of critically ill patients: a cross-sectional study Rosgen, B. K. Krewulak, K. D. Davidson, J. E. Ely, E. W. Stelfox, H. T. Fiest, K. M. BMC Psychiatry 2021

Adult
Anxiety/diagnosis
Anxiety Disorders
Caregivers
Critical Illness
Cross-Sectional Studies
Delirium/diagnosis
Depression/diagnosis
Humans
Anxiety
Caregiver
Depression
Family
Intensive care

A Core Outcome Set for Research Evaluating Interventions to Prevent and/or Treat Delirium in Critically Ill Adults: An International Consensus Study (Del-COrS) Rose, L. Burry, L. Agar, M. Campbell, N. L. Clarke, M. Lee, J. Marshall, J. C. Devlin, J. W. Blackwood, B. Needham, D. M. Siddiqi, N. Page, V. Crit Care Med 2021
Postoperative delirium is associated with decreased recovery of ambulation one-month after surgery Robinson, T. N. Kovar, A. Carmichael, H. Overbey, D. M. Goode, C. M. Jones, T. S. Am J Surg 2021

Aged
Delirium/ physiopathology
Female
Humans
Male
Middle Aged
Mobility Limitation
Postoperative Complications/ physiopathology
Postoperative Period
Recovery of Function
Accelerometer activity tracker
Ambulation
Older adults
Postoperative delirium

Emergence delirium in children: a Brazilian survey Quintão, V. C. Sales, C. K. O. Herrera, E. M. Ellerkmann, R. K. Rosen, H. D. Carmona, M. J. C. Braz J Anesthesiol 2021

Anesthesia
Child
Emergence delirium
Survey

Perioperative dexmedetomidine administration to prevent delirium in adults after non-cardiac surgery: A systematic review and meta-analysis Qin, C. Jiang, Y. Lin, C. Li, A. Liu, J. J Clin Anesth 2021

Adult
Aged
Bradycardia
Delirium/epidemiology/prevention & control
Dexmedetomidine
Humans
Hypotension
Postoperative Complications/epidemiology/prevention & control
Delirium
Intraoperative
Meta-analysis

Probable Delirium as a Risk Factor for Adverse Surgical Outcomes in Geriatric Patients With Acute Hip Fracture: Preoperative Assessment Using a Short Screening Tool Perkins, J. L. Perera, S. Beach, M. Esper, S. A. Gruen, G. S. Neft, M. AANA J 2021

Adverse outcomes
delirium
hip fracture
preoperative anesthesia

Cognitive Stimulation in an Intensive Care Unit: A Qualitative Evaluation of Barriers to and Facilitators of Implementation Parker, A. M. Aldabain, L. Akhlaghi, N. Glover, M. Yost, S. Velaetis, M. Lavezza, A. Mantheiy, E. Albert, K. Needham, D. M. Crit Care Nurse 2021
Does Delirium Phenomenology in Persons with Advanced Cancer Follow a Specific Pattern? Pallotti, M. C. Lopez-Fidalgo, J. Centeno, C. Celin, D. Biasco, G. Giovannini, M. Maltoni, M. Noguera, A. J Palliat Med 2021

Mdas
cancer
delirium
phenomenology

Dexmedetomidine, Delirium, and Adverse Outcomes: Analysis of the STS Adult Cardiac Surgery Database Pal, N. Abernathy, J. H., 3rd Taylor, M. A. Bollen, B. A. Shah, A. S. Feng, X. Shotwell, M. S. Kertai, M. D. Ann Thorac Surg 2021

cardiac surgery
delirium
dexmedetomidine
mortality
postoperative pain

Factors associated with delirium after cardiac surgery: A prospective cohort study Ordóñez-Velasco, L. M. Hernández-Leiva, E. Ann Card Anaesth 2021

Body mass index
cardiopulmonary bypass
cerebral near infrared spectroscopy
intensive care unit
postoperative delirium

Baseline sleep as a predictor of delirium after surgical aortic valve replacement: A feasibility study Oldham, M. A. Pigeon, W. R. Chapman, B. Yurcheshen, M. Knight, P. A. Lee, H. B. Gen Hosp Psychiatry 2021

Apnea/hypopnea index
Obstructive sleep apnea
Postoperative delirium
Sleep efficiency
Surgical aortic valve replacement

What Does a Diagnosis of Depression Mean for Patients Undergoing Colorectal Surgery? Oduyale, O. K. Eltahir, A. A. Stem, M. Prince, E. Zhang, G. Q. Safar, B. Efron, J. E. Atallah, C. J Surg Res 2021

Colorectal surgery
Depression
Mortality
Postoperative outcomes

A randomized double-blind placebo-controlled trial of intravenous thiamine for prevention of delirium following allogeneic hematopoietic stem cell transplantation Nakamura, Z. M. Deal, A. M. Park, E. M. Quillen, L. J. Chien, S. A. Stanton, K. E. McCabe, S. D. Heiling, H. M. Wood, W. A. Shea, T. C. Rosenstein, D. L. J Psychosom Res 2021

Cognitive impairment
Delirium
Hematopoietic stem cell transplantation
Thiamine
Wernicke’s encephalopathy
Wernicke-Korsakoff syndrome

The 4-DSD: A New Tool to Assess Delirium Superimposed on Moderate to Severe Dementia Morandi, A. Grossi, E. Lucchi, E. Zambon, A. Faraci, B. Severgnini, J. MacLullich, A. Smith, H. Pandharipande, P. Rizzini, A. Galeazzi, M. Massariello, F. Corradi, S. Raccichini, A. Scrimieri, A. Morichi, V. Gentile, S. Lucchini, F. Pecorella, L. Mossello J Am Med Dir Assoc 2021

Delirium
delirium superimposed on dementia
dementia
older

Are dexmedetomidine and olanzapine suitable to control delirium in critically ill elderly patients? A retrospective cohort study Liu, S. Zhao, R. Yang, R. Zhao, H. Ji, C. Duan, M. Liu, J. Biomed Pharmacother 2021

Critical illness
Delirium
Dexmedetomidine
Drug-related side effects and adverse reactions
Intensive care unit
Olanzapine

Association between glucose variability and postoperative delirium in acute aortic dissection patients: an observational study Lin, Y. J. Lin, L. Y. Peng, Y. C. Zhang, H. R. Chen, L. W. Huang, X. Z. Chen, Q. J Cardiothorac Surg 2021

Acute Disease
Adult
Aneurysm, Dissecting/blood/ surgery
Blood Glucose/ analysis
Cardiac Surgical Procedures/adverse effects
Cardiovascular Surgical Procedures/ adverse effects
Delirium/ blood/diagnosis/etiology
Female
Humans
Intensive Care Units
Length of Stay
Male
Middle Aged
Prognosis
Proportional Hazards Models
Prospective Studies
Risk Factors
Survival Analysis
Acute aortic dissection patient
Glucose variability
Postoperative delirium

Frailty is associated with a higher risk of developing delirium and cognitive impairment among patients with diabetic kidney disease: A longitudinal population-based cohort study Lee, S. Y. Wang, J. Chao, C. T. Chien, K. L. Huang, J. W. Diabet Med 2021

chronic kidney disease
cognitive impairment
delirium
diabetes mellitus
diabetic kidney disease
frail phenotype

Multi-Component Care Bundle in Geriatric Fracture Hip for Reducing Post-Operative Delirium Lam, D. M. H. Wang, C. Lee, A. K. H. Chung, Y. F. Lau, T. W. Fang, C. Leung, F. Chan, T. C. W. Geriatr Orthop Surg Rehabil 2021

delirium
fascia iliaca block
geriatric fracture hip
geriatric trauma
multi-component care bundle
postoperative delirium
ultrasound-guided fascia iliaca block

Occurrence of Delirium during ECMO Therapy in a Critical Care Unit in Poland-A Cross-Sectional Pilot Study Krupa, S. Friganovic, A. Mędrzycka-Dąbrowska, W. Int J Environ Res Public Health 2021

Critical Care
Cross-Sectional Studies
Delirium/epidemiology
Extracorporeal Membrane Oxygenation/adverse effects
Humans
Pilot Projects
Poland/epidemiology
delirium
extracorporeal membrane oxygenation

Steroids to reduce the impact on delirium (STRIDE): a double-blind, randomised, placebo-controlled feasibility trial of pre-operative dexamethasone in people with hip fracture Kluger, M. T. Skarin, M. Collier, J. Rice, D. A. McNair, P. J. Seow, M. Y. Connolly, M. J. Anaesthesia 2021

delirium
dexamethasone
hip fracture
prevention

Elevated plasma levels of galectin-3 binding protein are associated with post-stroke delirium - A pilot study Klimiec-Moskal, E. Pasinska, P. Kowalska, K. Klimkowicz-Mrowiec, A. Pera, J. Slowik, A. Dziedzic, T. J Neuroimmunol 2021

Delirium
Gal-3BP
Hmgb1
Inflammation
Ischemic stroke

Postoperative delirium after cardiac surgery of elderly patients as an independent risk factor for prolonged length of stay in intensive care unit and in hospital Kirfel, A. Menzenbach, J. Guttenthaler, V. Feggeler, J. Mayr, A. Coburn, M. Wittmann, M. Aging Clin Exp Res 2021

Cardiac surgery
Diagnosis of delirium
Elderly patients
Length of stay
Postoperative delirium

ED-DEL: Development of a change package and toolkit for delirium in the emergency department Kennedy, M. Webb, M. Gartaganis, S. Hwang, U. Biese, K. Stuck, A. Lesser, A. Hshieh, T. Inouye, S. K. J Am Coll Emerg Physicians Open 2021

aging
delirium
emergency department
geriatrics
organizational innovation
quality assurance
quality improvement

Elevated Monocyte Chemoattractant Protein-1 as the Independent Risk Factor of Delirium after Cardiac Surgery. A Prospective Cohort Study Kaźmierski, J. Miler, P. Pawlak, A. Jerczyńska, H. Woźniak, J. Frankowska, E. Brzezińska, A. Woźniak, K. Krejca, M. Wilczyński, M. J Clin Med 2021

cardiac surgery
coronary artery bypass grafting
delirium
high-sensitivity C-reactive protein
monocyte chemoattractant protein-1

Prevalence of and factors associated with physical restraint use in the intensive care unit: a multicenter prospective observational study in Japan Kawai, Y. Hamamoto, M. Miura, A. Yamaguchi, M. Masuda, Y. Iwata, M. Kanbe, M. Ikematsu, Y. Intern Emerg Med 2021

Associated factors
Intensive care unit (ICU)
Physical restraint
Prevalence

Added value of anxiolytic benzodiazepines in predictive models on severe delirium in patients with acute decompensated heart failure: A retrospective analysis Kawada, K. Fukuda, H. Kubo, T. Ohta, T. Ishida, T. Morisawa, S. Kawazoe, T. Okamoto, M. Fujita, H. Jobu, K. Morita, Y. Ueba, T. Kitaoka, H. Miyamura, M. PLoS One 2021
Sagittal alignment changes and postoperative complications following surgery for adult spinal deformity in patients with Parkinson's disease: a multi-institutional retrospective cohort study Kawabata, A. Yoshii, T. Sakai, K. Hirai, T. Yuasa, M. Inose, H. Matsukura, Y. Morishita, S. Tomori, M. Torigoe, I. Kusano, K. Otani, K. Arai, Y. Shindo, S. Okawa, A. BMC Musculoskelet Disord 2021

Follow-Up Studies
Humans
Parkinson Disease/complications/epidemiology
Postoperative Complications/diagnostic imaging/epidemiology/etiology
Retrospective Studies
Spinal Fusion/adverse effects
Adult spinal deformity
Parkinson’s disease
Postoperative complications
Radiographic parameters
Sagittal alignment
Sagittal vertical axis

Factors associated with post-electroconvulsive therapy delirium: A retrospective chart review study Jo, Y. T. Joo, S. W. Lee, J. Joo, Y. H. Medicine (Baltimore) 2021

Adult
Anesthetics/administration & dosage/ adverse effects
Case-Control Studies
Delirium/ etiology
Electroconvulsive Therapy/ adverse effects/methods
Etomidate/administration & dosage/ adverse effects
Female
Humans
Male
Middle Aged
Retrospective Studies

Association of Delirium during Critical Illness With Mortality: Multicenter Prospective Cohort Study Hughes, C. G. Hayhurst, C. J. Pandharipande, P. P. Shotwell, M. S. Feng, X. Wilson, J. E. Brummel, N. E. Girard, T. D. Jackson, J. C. Ely, E. W. Patel, M. B. Anesth Analg 2021
Validating the Mandarin version of the Memorial delirium assessment scale in general medical hospital patients Hu, C. H. Chiu, Y. C. Liu, S. I. Ko, K. T. Asia Pac Psychiatry 2021

confusion assessment method
delirium
memorial delirium assessment scale
mini-mental state examination
receiver operating characteristic curve

How do delirium motor subtypes differ in phenomenology and contributory aetiology? a cross-sectional, multisite study of liaison psychiatry and palliative care patients Glynn, K. McKenna, F. Lally, K. O'Donnell, M. Grover, S. Chakrabarti, S. Avasthi, A. Mattoo, S. K. Sharma, A. Gosh, A. Shah, R. Hickey, D. Fitzgerald, J. Davis, B. O'Regan, N. Adamis, D. Williams, O. Awan, F. Dunne, C. Cullen, W. McInerney, S. McFarland, BMJ Open 2021

Adult
Cross-Sectional Studies
Delirium/diagnosis/etiology
Humans
India
Ireland/epidemiology
Palliative Care
Psychiatry
Severity of Illness Index
delirium & cognitive disorders
dementia
geriatric medicine

Frailty, post-operative delirium and functional status at discharge in patients with hip fracture Gandossi, C. M. Zambon, A. Oliveri, G. Codognola, M. Szabo, H. Cazzulani, I. Ferrara, M. C. Mottadelli, C. Galeazzi, M. Amoroso, I. Zarcone, C. Principato, G. Corsi, M. Mazzola, P. Zatti, G. Foti, G. Bellelli, G. Int J Geriatr Psychiatry 2021

delirium
elderly
frailty
functional outcome
hip fracture
orthogeriatric

The Safety and Efficacy Evaluation of Dexmedetomidine for Procedural Sedation and Postoperative Behaviors in Pediatric Populations: A Systematic Review and Meta-analysis Gan, L. Zhao, X. Chen, X. Ann Pharmacother 2021

delirium
dexmedetomidine
meta-analysis
postoperative behavior
sedation

Association between frailty and postoperative delirium: a meta-analysis of cohort study Fu, D. Tan, X. Zhang, M. Chen, L. Yang, J. Aging Clin Exp Res 2021

Cohort studies
Frailty
Meta-analysis
Postoperative delirium

Incidence and factors associated with delirium in children in a single pediatric intensive care unit in Brazil Flores, A. E. R. Oura, K. H. U. Rocha, P. K. Belela-Anacleto, A. S. C. Kusahara, D. M. J Pediatr Nurs 2021

Delirium
Pediatric intensive care units
Pediatric nursing
Risk factors

Long-Term Outcomes in Intensive Care Unit Patients with Delirium: A Population-Based Cohort Study Fiest, K. M. Soo, A. Hee Lee, C. Niven, D. J. Ely, E. W. Doig, C. J. Stelfox, H. T. Am J Respir Crit Care Med 2021

critical care
delirium
mortality

Impact of Religiosity on Delirium Severity Among Critically Ill Shi'a Muslims: A Prospective Multi-Center Observational Study Farzanegan, B. Elkhatib, T. H. M. Elgazzar, A. E. Moghaddam, K. G. Torkaman, M. Zarkesh, M. Goharani, R. Bashar, F. R. Hajiesmaeili, M. Shojaei, S. Madani, S. J. Vahedian-Azimi, A. Hatamian, S. Mosavinasab, S. M. M. Khoshfetrat, M. Khatir, A. K. Miller, A J Relig Health 2021

Critical Illness
Delirium
Female
Humans
Iran
Islam
Prospective Studies
Critical care
Intensive care unit
Religion
Religiosity

Depression as a predictor of postoperative delirium after cardiac surgery: a systematic review and meta-analysis Falk, A. Kåhlin, J. Nymark, C. Hultgren, R. Stenman, M. Interact Cardiovasc Thorac Surg 2021

Cardiac surgery
Depression
Meta-analysis
Postoperative delirium

The delirium screening tool 4AT in routine clinical practice: prediction of mortality, sensitivity and specificity Evensen, S. Hylen Ranhoff, A. Lydersen, S. Saltvedt, I. Eur Geriatr Med 2021

4at
Delirium
Delirium screening
Geriatrics

Delirium and Associated Length of Stay and Costs in Critically Ill Patients Dziegielewski, C. Skead, C. Canturk, T. Webber, C. Fernando, S. M. Thompson, L. H. Foster, M. Ristovic, V. Lawlor, P. G. Chaudhuri, D. Dave, C. Herritt, B. Bush, S. H. Kanji, S. Tanuseputro, P. Thavorn, K. Rosenberg, E. Kyeremanteng, K. Crit Care Res Pract 2021
Opioid Use Increases the Risk of Delirium in Critically Ill Adults Independently of Pain Duprey, M. S. Dijkstra-Kersten, S. M. A. Zaal, I. J. Briesacher, B. A. Saczynski, J. S. Griffith, J. L. Devlin, J. W. Slooter, A. J. C. Am J Respir Crit Care Med 2021

delirium
intensive care
medication
opioid
pain

Association Between Incident Delirium Treatment With Haloperidol and Mortality in Critically Ill Adults uprey, M. S. Devlin, J. W. van der Hoeven, J. G. Pickkers, P. Briesacher, B. A. Saczynski, J. S. Griffith, J. L. van den Boogaard, M. Crit Care Med 2021
Descriptive analysis of the unwarranted continuation of antipsychotics for the management of ICU delirium during transitions of care: A multicenter evaluation across New Jersey Dixit, D. Andrews, L. B. Radparvar, S. Adams, C. Kumar, S. T. Cardinale, M. Am J Health Syst Pharm 2021

ICU delirium
antipsychotics
inappropriate prescribing
intensive care unit
medication safety
transitions of care

Cluster nursing can reduce postoperative delirium and improve the negative emotions and quality of life of elderly ICU patients Di, J. Wang, X. Chen, J. Am J Transl Res 2021

Cluster nursing
delirium
elderly
intensive care unit
quality of life


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