Delirium Bibliography

The searchable delirium bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons.  The NIDUS team keeps it updated for you on a monthly basis!  Feel free to search by author, title, year, keywords. It is primarily intended for clinicians and researchers interested in exploring these topics.

To retrieve full information, click on the title of the article and scroll down to read the abstract, journal, etc.

Each article is indexed by keywords taken from MEDLINE and other relevant databases.

You may base your search on as many search terms as you like. A search term can be a keyword, an author’s name, all or part of an article’s title, or the year of publication.

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Total Records Found: 4240, showing 100 per page
TitleAuthorsJournalYearKeywords
The frequency and quality of delirium documentation in discharge summaries Chuen, V. L. Chan, A. C. H. Ma, J. Alibhai, S. M. H. Chau, V. BMC Geriatr 2021

Delirium/diagnosis/epidemiology
Documentation
Hospitalization
Humans
Patient Discharge
Retrospective Studies
Delirium
Discharge summary
Geriatrics
Quality

Using data linkage for national surveillance of clinical quality indicators for dementia care among Australian aged care users Cations, M. Lang, C. Ward, S. A. Caughey, G. E. Crotty, M. Whitehead, C. Ahern, S. Maddison, J. Inacio, M. C. Sci Rep 2021
Geriatric fracture centre vs usual care after proximal femur fracture in older patients: what are the benefits? Results of a large international prospective multicentre study Blauth, M. Joeris, A. Rometsch, E. Espinoza-Rebmann, K. Wattanapanom, P. Jarayabhand, R. Poeze, M. Wong, M. K. Kwek, E. B. K. Hegeman, J. H. Perez-Uribarri, C. Guerado, E. Revak, T. J. Zohner, S. Joseph, D. Gosch, M. BMJ Open 2021

Aged
Aged, 80 and over
Cohort Studies
Femur
Hip Fractures/surgery
Humans
Prospective Studies
Quality of Life
geriatric medicine
health services administration & management
hip
orthopaedic & trauma surgery
trauma management

Effects of dexmedetomidine on neurocognitive disturbance after elective non-cardiac surgery in senile patients: a systematic review and meta-analysis Bi, X. Wei, J. Zhang, X. J Int Med Res 2021

China
Cognitive Dysfunction/drug therapy/prevention & control
Delirium
Dexmedetomidine/therapeutic use
Humans
Hypotension
Postoperative Complications/prevention & control
Anesthesiology
dexmedetomidine
non-cardiac surgery
postoperative cognitive disturbance
postoperative delirium
senile

Non-pharmacological interventions for preventing delirium in hospitalised non-ICU patients (Review) Burton JK, Craig LE, Yong SQ, Siddiqi N, Teale EA, Woodhouse R, Barugh AJ, Shepherd AM, Brunton A, Freeman SC, Sutton AJ, Quinn TJ Cochrane Database of Systematic Reviews 2021
Incidence and risk factors for postoperative delirium after liver transplantation: a systematic review and meta-analysis Zhou, S. Deng, F. Zhang, J. Chen, G. Eur Rev Med Pharmacol Sci 2021
The perioperative application of continuous cerebral autoregulation monitoring for cerebral protection in elderly patients Zhang, Y. Tan, J. Li, P. Zhang, X. Yang, Y. Liu, Y. Fu, Q. Cao, J. Mi, W. Zhang, H. Li, H. Ann Palliat Med 2021

Aged
Arterial Pressure
Cerebrovascular Circulation
Homeostasis
Humans
Male
Middle Aged
Oximetry
Spectroscopy, Near-Infrared
Cerebral autoregulation (CA)
optimal mean arterial pressure (optimal MAP)
regional cerebral oxygen saturation (rScO2)
robotic-assisted laparoscopic radical prostatectomy (RALP)

Prospective Randomized Controlled Pilot Study of High-Intensity Lightbox Phototherapy to Prevent ICU-Acquired Delirium Incidence Zhang, K. S. Pelleg, T. Hussain, S. Kollipara, V. Loschner, A. Foroozesh, M. B. Rubio, E. Biscardi, F. Ie, S. R. Cureus 2021

bright light therapy
circadian rhythm
delirium in icu
icu delirium
prolonged mechanical ventilation
quality improvement and patient safety

Neurocognitive disorders in the elderly: altered functional resting-state hyperconnectivities in postoperative delirium patients Winterer, J. M. Ofosu, K. Borchers, F. Hadzidiakos, D. Lammers-Lietz, F. Spies, C. Winterer, G. Zacharias, N. Transl Psychiatry 2021

Aged
Delirium
Humans
Magnetic Resonance Imaging
Prefrontal Cortex
Prospective Studies
Rest

Relationships between preoperative cortical thickness, postoperative electroencephalogram slowing, and postoperative delirium White, M. F. Tanabe, S. Casey, C. Parker, M. Bo, A. Kunkel, D. Nair, V. Pearce, R. A. Lennertz, R. Prabhakaran, V. Lindroth, H. Sanders, R. D. Br J Anaesth 2021

cortical slowing
cortical thickness
delirium
neurodegeneration
surgery

COVID-19 in adults with dementia: clinical features and risk factors of mortality-a clinical cohort study on 125 patients Vrillon, A. Mhanna, E. Aveneau, C. Lebozec, M. Grosset, L. Nankam, D. Albuquerque, F. Razou Feroldi, R. Maakaroun, B. Pissareva, I. Cherni Gherissi, D. Azuar, J. François, V. Hourrègue, C. Dumurgier, J. Volpe-Gillot, L. Paquet, C. Alzheimers Res Ther 2021

Aged, 80 and over
COVID-19/complications/ mortality
COVID-19 Testing
Comorbidity
Dementia/complications/virology
Female
France/epidemiology
Humans
Male
Prospective Studies
Risk Factors
Covid-19
Dementia
Mortality
Prognostic factors
SARS-CoV-2

Risk Factors for Delirium after Vascular Surgery: A Systematic Review and Meta-Analysis Visser, L. Prent, A. Banning, L. B. D. van Leeuwen, B. L. Zeebregts, C. J. Pol, R. A. Ann Vasc Surg 2021
Etiologies of Delirium in Consecutive COVID-19 Inpatients and the Relationship Between Severity of Delirium and COVID-19 in a Prospective Study With Follow-Up Velásquez-Tirado, J. D. Trzepacz, P. T. Franco, J. G. J Neuropsychiatry Clin Neurosci 2021

Covid-19
Delirium
Psychiatric Status Rating Scales
Severity of Illness Index

Increased Emergency Department Hallway Length of Stay is Associated with Development of Delirium van Loveren, K. Singla, A. Sinvani, L. Calandrella, C. Perera, T. Brave, M. Becker, L. Li, T. West J Emerg Med 2021

Adolescent
Adult
Aged
Case-Control Studies
Causality
Delirium/ epidemiology/physiopathology
Emergency Service, Hospital/ statistics & numerical data
Humans
Length of Stay
Logistic Models
Male
Middle Aged
Pilot Projects
Retrospective Studies
Time-to-Treatment

Delirium in Children Undergoing Hematopoietic Cell Transplantation: A Multi-Institutional Point Prevalence Study Traube, C. Gerber, L. M. Mauer, E. A. Small, K. Broglie, L. Chopra, Y. R. Duncan, C. N. Ebens, C. L. Fitzgerald, J. C. Freedman, J. L. Hudspeth, M. P. Hurley, C. Mahadeo, K. M. McArthur, J. Shapiro, M. C. Sharron, M. P. Wall, D. A. Zinter, M. S. Greenwald Front Oncol 2021

cancer
cornell assessment of pediatric delirium
delirium
hematopoietic cell transplant
incidence
pediatric oncology
risk factors

Agreement Between the Mini-Cog in the Preoperative Clinic and on the Day of Surgery and Association With Postanesthesia Care Unit Delirium: A Cohort Study of Cognitive Screening in Older Adults Tiwary, N. Treggiari, M. M. Yanez, N. D. Kirsch, J. R. Tekkali, P. Taylor, C. C. Schenning, K. J. Anesth Analg 2021

Aged
Aged, 80 and over
Anesthesia Recovery Period
Anesthesia, General/ adverse effects
Cognition
Cognitive Dysfunction/complications/ diagnosis/psychology
Elective Surgical Procedures/ adverse effects
Emergence Delirium/diagnosis/ etiology/psychology
Female
Humans
Male
Mental Status and Dementia Tests
Predictive Value of Tests
Preoperative Care
Reproducibility of Results
Risk Assessment
Risk Factors
Treatment Outcome

A qualitative analysis of clinicians' communication strategies with family members of patients experiencing hospital-acquired delirium Taylor, G. B. Radhakrishnan, N. Fisher, C. L. Price, C. Tighe, P. Le, T. Bylund, C. L. Geriatr Nurs 2021
A scalable approach for developing clinical risk prediction applications in different hospitals Sun, H. Depraetere, K. Meesseman, L. De Roo, J. Vanbiervliet, M. De Baerdemaeker, J. Muys, H. von Dossow, V. Hulde, N. Szymanowsky, R. J Biomed Inform 2021

Acute kidney injury
Clinical decision support
Delirium
Electronic health records (EHR)
Machine learning
Scalability
Sepsis

The Relative Impact of Specific Postoperative Complications on Older Patients Undergoing Hip Fracture Repair Stahl, C. C. Funk, L. M. Schumacher, J. R. Zarzaur, B. L. Scarborough, J. E. Jt Comm J Qual Patient Saf 2021
Brain MRI after critical care admission: A longitudinal imaging study Sprung, J. Warner, D. O. Knopman, D. S. Petersen, R. C. Mielke, M. M. Jack, C. R., Jr. Martin, D. P. Hanson, A. C. Schroeder, D. R. Przybelski, S. A. Schulte, P. J. Laporta, M. L. Weingarten, T. N. Vemuri, P. J Crit Care 2021

AD-signature cortex
Corpus callosum
Cortical thinning
Hippocampus
Intensive care unit
Magnetic resonance imaging
Older adults

Effect of age on dexmedetomidine treatment for ventilated patients with sepsis: a post-hoc analysis of the DESIRE trial Sato, T. Kawazoe, Y. Miyagawa, N. Yokokawa, Y. Kushimoto, S. Miyamoto, K. Ohta, Y. Morimoto, T. Yamamura, H. Acute Med Surg 2021

Delirium
dexmedetomidine
elderly
sedative effect
sepsis

Effects of comprehensive geriatric care models on postoperative outcomes in geriatric surgical patients: a systematic review and meta-analysis Saripella, A. Wasef, S. Nagappa, M. Riazi, S. Englesakis, M. Wong, J. Chung, F. BMC Anesthesiol 2021

Adverse outcomes
Comprehensive geriatric assessment
Comprehensive geriatric care model
Delirium
Elderly
Surgery
Long-Term Care

Influence of Age on Postoperative Neurological Outcomes after Surgery of Acute Type A Aortic Dissection Salem, M. Salib, M. Friedrich, C. Salem, M. Puehler, T. Schoettler, J. Schoeneich, F. Cremer, J. Haneya, A. J Clin Med 2021

acute type A aortic dissection
moderate hypothermic circulatory arrest
neurological complication in elderly after type A aortic dissection

Associations between caregiver-detected delirium and symptoms of depression and anxiety in family caregivers of critically ill patients: a cross-sectional study Rosgen, B. K. Krewulak, K. D. Davidson, J. E. Ely, E. W. Stelfox, H. T. Fiest, K. M. BMC Psychiatry 2021

Adult
Anxiety/diagnosis
Anxiety Disorders
Caregivers
Critical Illness
Cross-Sectional Studies
Delirium/diagnosis
Depression/diagnosis
Humans
Anxiety
Caregiver
Depression
Family
Intensive care

A Core Outcome Set for Research Evaluating Interventions to Prevent and/or Treat Delirium in Critically Ill Adults: An International Consensus Study (Del-COrS) Rose, L. Burry, L. Agar, M. Campbell, N. L. Clarke, M. Lee, J. Marshall, J. C. Devlin, J. W. Blackwood, B. Needham, D. M. Siddiqi, N. Page, V. Crit Care Med 2021
Postoperative delirium is associated with decreased recovery of ambulation one-month after surgery Robinson, T. N. Kovar, A. Carmichael, H. Overbey, D. M. Goode, C. M. Jones, T. S. Am J Surg 2021

Aged
Delirium/ physiopathology
Female
Humans
Male
Middle Aged
Mobility Limitation
Postoperative Complications/ physiopathology
Postoperative Period
Recovery of Function
Accelerometer activity tracker
Ambulation
Older adults
Postoperative delirium

Emergence delirium in children: a Brazilian survey Quintão, V. C. Sales, C. K. O. Herrera, E. M. Ellerkmann, R. K. Rosen, H. D. Carmona, M. J. C. Braz J Anesthesiol 2021

Anesthesia
Child
Emergence delirium
Survey

Perioperative dexmedetomidine administration to prevent delirium in adults after non-cardiac surgery: A systematic review and meta-analysis Qin, C. Jiang, Y. Lin, C. Li, A. Liu, J. J Clin Anesth 2021

Adult
Aged
Bradycardia
Delirium/epidemiology/prevention & control
Dexmedetomidine
Humans
Hypotension
Postoperative Complications/epidemiology/prevention & control
Delirium
Intraoperative
Meta-analysis

Probable Delirium as a Risk Factor for Adverse Surgical Outcomes in Geriatric Patients With Acute Hip Fracture: Preoperative Assessment Using a Short Screening Tool Perkins, J. L. Perera, S. Beach, M. Esper, S. A. Gruen, G. S. Neft, M. AANA J 2021

Adverse outcomes
delirium
hip fracture
preoperative anesthesia

Cognitive Stimulation in an Intensive Care Unit: A Qualitative Evaluation of Barriers to and Facilitators of Implementation Parker, A. M. Aldabain, L. Akhlaghi, N. Glover, M. Yost, S. Velaetis, M. Lavezza, A. Mantheiy, E. Albert, K. Needham, D. M. Crit Care Nurse 2021
Does Delirium Phenomenology in Persons with Advanced Cancer Follow a Specific Pattern? Pallotti, M. C. Lopez-Fidalgo, J. Centeno, C. Celin, D. Biasco, G. Giovannini, M. Maltoni, M. Noguera, A. J Palliat Med 2021

Mdas
cancer
delirium
phenomenology

Dexmedetomidine, Delirium, and Adverse Outcomes: Analysis of the STS Adult Cardiac Surgery Database Pal, N. Abernathy, J. H., 3rd Taylor, M. A. Bollen, B. A. Shah, A. S. Feng, X. Shotwell, M. S. Kertai, M. D. Ann Thorac Surg 2021

cardiac surgery
delirium
dexmedetomidine
mortality
postoperative pain

Factors associated with delirium after cardiac surgery: A prospective cohort study Ordóñez-Velasco, L. M. Hernández-Leiva, E. Ann Card Anaesth 2021

Body mass index
cardiopulmonary bypass
cerebral near infrared spectroscopy
intensive care unit
postoperative delirium

Baseline sleep as a predictor of delirium after surgical aortic valve replacement: A feasibility study Oldham, M. A. Pigeon, W. R. Chapman, B. Yurcheshen, M. Knight, P. A. Lee, H. B. Gen Hosp Psychiatry 2021

Apnea/hypopnea index
Obstructive sleep apnea
Postoperative delirium
Sleep efficiency
Surgical aortic valve replacement

What Does a Diagnosis of Depression Mean for Patients Undergoing Colorectal Surgery? Oduyale, O. K. Eltahir, A. A. Stem, M. Prince, E. Zhang, G. Q. Safar, B. Efron, J. E. Atallah, C. J Surg Res 2021

Colorectal surgery
Depression
Mortality
Postoperative outcomes

A randomized double-blind placebo-controlled trial of intravenous thiamine for prevention of delirium following allogeneic hematopoietic stem cell transplantation Nakamura, Z. M. Deal, A. M. Park, E. M. Quillen, L. J. Chien, S. A. Stanton, K. E. McCabe, S. D. Heiling, H. M. Wood, W. A. Shea, T. C. Rosenstein, D. L. J Psychosom Res 2021

Cognitive impairment
Delirium
Hematopoietic stem cell transplantation
Thiamine
Wernicke’s encephalopathy
Wernicke-Korsakoff syndrome

The 4-DSD: A New Tool to Assess Delirium Superimposed on Moderate to Severe Dementia Morandi, A. Grossi, E. Lucchi, E. Zambon, A. Faraci, B. Severgnini, J. MacLullich, A. Smith, H. Pandharipande, P. Rizzini, A. Galeazzi, M. Massariello, F. Corradi, S. Raccichini, A. Scrimieri, A. Morichi, V. Gentile, S. Lucchini, F. Pecorella, L. Mossello J Am Med Dir Assoc 2021

Delirium
delirium superimposed on dementia
dementia
older

Are dexmedetomidine and olanzapine suitable to control delirium in critically ill elderly patients? A retrospective cohort study Liu, S. Zhao, R. Yang, R. Zhao, H. Ji, C. Duan, M. Liu, J. Biomed Pharmacother 2021

Critical illness
Delirium
Dexmedetomidine
Drug-related side effects and adverse reactions
Intensive care unit
Olanzapine

Association between glucose variability and postoperative delirium in acute aortic dissection patients: an observational study Lin, Y. J. Lin, L. Y. Peng, Y. C. Zhang, H. R. Chen, L. W. Huang, X. Z. Chen, Q. J Cardiothorac Surg 2021

Acute Disease
Adult
Aneurysm, Dissecting/blood/ surgery
Blood Glucose/ analysis
Cardiac Surgical Procedures/adverse effects
Cardiovascular Surgical Procedures/ adverse effects
Delirium/ blood/diagnosis/etiology
Female
Humans
Intensive Care Units
Length of Stay
Male
Middle Aged
Prognosis
Proportional Hazards Models
Prospective Studies
Risk Factors
Survival Analysis
Acute aortic dissection patient
Glucose variability
Postoperative delirium

Frailty is associated with a higher risk of developing delirium and cognitive impairment among patients with diabetic kidney disease: A longitudinal population-based cohort study Lee, S. Y. Wang, J. Chao, C. T. Chien, K. L. Huang, J. W. Diabet Med 2021

chronic kidney disease
cognitive impairment
delirium
diabetes mellitus
diabetic kidney disease
frail phenotype

Multi-Component Care Bundle in Geriatric Fracture Hip for Reducing Post-Operative Delirium Lam, D. M. H. Wang, C. Lee, A. K. H. Chung, Y. F. Lau, T. W. Fang, C. Leung, F. Chan, T. C. W. Geriatr Orthop Surg Rehabil 2021

delirium
fascia iliaca block
geriatric fracture hip
geriatric trauma
multi-component care bundle
postoperative delirium
ultrasound-guided fascia iliaca block

Occurrence of Delirium during ECMO Therapy in a Critical Care Unit in Poland-A Cross-Sectional Pilot Study Krupa, S. Friganovic, A. Mędrzycka-Dąbrowska, W. Int J Environ Res Public Health 2021

Critical Care
Cross-Sectional Studies
Delirium/epidemiology
Extracorporeal Membrane Oxygenation/adverse effects
Humans
Pilot Projects
Poland/epidemiology
delirium
extracorporeal membrane oxygenation

Steroids to reduce the impact on delirium (STRIDE): a double-blind, randomised, placebo-controlled feasibility trial of pre-operative dexamethasone in people with hip fracture Kluger, M. T. Skarin, M. Collier, J. Rice, D. A. McNair, P. J. Seow, M. Y. Connolly, M. J. Anaesthesia 2021

delirium
dexamethasone
hip fracture
prevention

Elevated plasma levels of galectin-3 binding protein are associated with post-stroke delirium - A pilot study Klimiec-Moskal, E. Pasinska, P. Kowalska, K. Klimkowicz-Mrowiec, A. Pera, J. Slowik, A. Dziedzic, T. J Neuroimmunol 2021

Delirium
Gal-3BP
Hmgb1
Inflammation
Ischemic stroke

Postoperative delirium after cardiac surgery of elderly patients as an independent risk factor for prolonged length of stay in intensive care unit and in hospital Kirfel, A. Menzenbach, J. Guttenthaler, V. Feggeler, J. Mayr, A. Coburn, M. Wittmann, M. Aging Clin Exp Res 2021

Cardiac surgery
Diagnosis of delirium
Elderly patients
Length of stay
Postoperative delirium

ED-DEL: Development of a change package and toolkit for delirium in the emergency department Kennedy, M. Webb, M. Gartaganis, S. Hwang, U. Biese, K. Stuck, A. Lesser, A. Hshieh, T. Inouye, S. K. J Am Coll Emerg Physicians Open 2021

aging
delirium
emergency department
geriatrics
organizational innovation
quality assurance
quality improvement

Elevated Monocyte Chemoattractant Protein-1 as the Independent Risk Factor of Delirium after Cardiac Surgery. A Prospective Cohort Study Kaźmierski, J. Miler, P. Pawlak, A. Jerczyńska, H. Woźniak, J. Frankowska, E. Brzezińska, A. Woźniak, K. Krejca, M. Wilczyński, M. J Clin Med 2021

cardiac surgery
coronary artery bypass grafting
delirium
high-sensitivity C-reactive protein
monocyte chemoattractant protein-1

Prevalence of and factors associated with physical restraint use in the intensive care unit: a multicenter prospective observational study in Japan Kawai, Y. Hamamoto, M. Miura, A. Yamaguchi, M. Masuda, Y. Iwata, M. Kanbe, M. Ikematsu, Y. Intern Emerg Med 2021

Associated factors
Intensive care unit (ICU)
Physical restraint
Prevalence

Added value of anxiolytic benzodiazepines in predictive models on severe delirium in patients with acute decompensated heart failure: A retrospective analysis Kawada, K. Fukuda, H. Kubo, T. Ohta, T. Ishida, T. Morisawa, S. Kawazoe, T. Okamoto, M. Fujita, H. Jobu, K. Morita, Y. Ueba, T. Kitaoka, H. Miyamura, M. PLoS One 2021
Sagittal alignment changes and postoperative complications following surgery for adult spinal deformity in patients with Parkinson's disease: a multi-institutional retrospective cohort study Kawabata, A. Yoshii, T. Sakai, K. Hirai, T. Yuasa, M. Inose, H. Matsukura, Y. Morishita, S. Tomori, M. Torigoe, I. Kusano, K. Otani, K. Arai, Y. Shindo, S. Okawa, A. BMC Musculoskelet Disord 2021

Follow-Up Studies
Humans
Parkinson Disease/complications/epidemiology
Postoperative Complications/diagnostic imaging/epidemiology/etiology
Retrospective Studies
Spinal Fusion/adverse effects
Adult spinal deformity
Parkinson’s disease
Postoperative complications
Radiographic parameters
Sagittal alignment
Sagittal vertical axis

Factors associated with post-electroconvulsive therapy delirium: A retrospective chart review study Jo, Y. T. Joo, S. W. Lee, J. Joo, Y. H. Medicine (Baltimore) 2021

Adult
Anesthetics/administration & dosage/ adverse effects
Case-Control Studies
Delirium/ etiology
Electroconvulsive Therapy/ adverse effects/methods
Etomidate/administration & dosage/ adverse effects
Female
Humans
Male
Middle Aged
Retrospective Studies

Association of Delirium during Critical Illness With Mortality: Multicenter Prospective Cohort Study Hughes, C. G. Hayhurst, C. J. Pandharipande, P. P. Shotwell, M. S. Feng, X. Wilson, J. E. Brummel, N. E. Girard, T. D. Jackson, J. C. Ely, E. W. Patel, M. B. Anesth Analg 2021
Validating the Mandarin version of the Memorial delirium assessment scale in general medical hospital patients Hu, C. H. Chiu, Y. C. Liu, S. I. Ko, K. T. Asia Pac Psychiatry 2021

confusion assessment method
delirium
memorial delirium assessment scale
mini-mental state examination
receiver operating characteristic curve

How do delirium motor subtypes differ in phenomenology and contributory aetiology? a cross-sectional, multisite study of liaison psychiatry and palliative care patients Glynn, K. McKenna, F. Lally, K. O'Donnell, M. Grover, S. Chakrabarti, S. Avasthi, A. Mattoo, S. K. Sharma, A. Gosh, A. Shah, R. Hickey, D. Fitzgerald, J. Davis, B. O'Regan, N. Adamis, D. Williams, O. Awan, F. Dunne, C. Cullen, W. McInerney, S. McFarland, BMJ Open 2021

Adult
Cross-Sectional Studies
Delirium/diagnosis/etiology
Humans
India
Ireland/epidemiology
Palliative Care
Psychiatry
Severity of Illness Index
delirium & cognitive disorders
dementia
geriatric medicine

Frailty, post-operative delirium and functional status at discharge in patients with hip fracture Gandossi, C. M. Zambon, A. Oliveri, G. Codognola, M. Szabo, H. Cazzulani, I. Ferrara, M. C. Mottadelli, C. Galeazzi, M. Amoroso, I. Zarcone, C. Principato, G. Corsi, M. Mazzola, P. Zatti, G. Foti, G. Bellelli, G. Int J Geriatr Psychiatry 2021

delirium
elderly
frailty
functional outcome
hip fracture
orthogeriatric

The Safety and Efficacy Evaluation of Dexmedetomidine for Procedural Sedation and Postoperative Behaviors in Pediatric Populations: A Systematic Review and Meta-analysis Gan, L. Zhao, X. Chen, X. Ann Pharmacother 2021

delirium
dexmedetomidine
meta-analysis
postoperative behavior
sedation

Association between frailty and postoperative delirium: a meta-analysis of cohort study Fu, D. Tan, X. Zhang, M. Chen, L. Yang, J. Aging Clin Exp Res 2021

Cohort studies
Frailty
Meta-analysis
Postoperative delirium

Incidence and factors associated with delirium in children in a single pediatric intensive care unit in Brazil Flores, A. E. R. Oura, K. H. U. Rocha, P. K. Belela-Anacleto, A. S. C. Kusahara, D. M. J Pediatr Nurs 2021

Delirium
Pediatric intensive care units
Pediatric nursing
Risk factors

Long-Term Outcomes in Intensive Care Unit Patients with Delirium: A Population-Based Cohort Study Fiest, K. M. Soo, A. Hee Lee, C. Niven, D. J. Ely, E. W. Doig, C. J. Stelfox, H. T. Am J Respir Crit Care Med 2021

critical care
delirium
mortality

Impact of Religiosity on Delirium Severity Among Critically Ill Shi'a Muslims: A Prospective Multi-Center Observational Study Farzanegan, B. Elkhatib, T. H. M. Elgazzar, A. E. Moghaddam, K. G. Torkaman, M. Zarkesh, M. Goharani, R. Bashar, F. R. Hajiesmaeili, M. Shojaei, S. Madani, S. J. Vahedian-Azimi, A. Hatamian, S. Mosavinasab, S. M. M. Khoshfetrat, M. Khatir, A. K. Miller, A J Relig Health 2021

Critical Illness
Delirium
Female
Humans
Iran
Islam
Prospective Studies
Critical care
Intensive care unit
Religion
Religiosity

Depression as a predictor of postoperative delirium after cardiac surgery: a systematic review and meta-analysis Falk, A. Kåhlin, J. Nymark, C. Hultgren, R. Stenman, M. Interact Cardiovasc Thorac Surg 2021

Cardiac surgery
Depression
Meta-analysis
Postoperative delirium

The delirium screening tool 4AT in routine clinical practice: prediction of mortality, sensitivity and specificity Evensen, S. Hylen Ranhoff, A. Lydersen, S. Saltvedt, I. Eur Geriatr Med 2021

4at
Delirium
Delirium screening
Geriatrics

Delirium and Associated Length of Stay and Costs in Critically Ill Patients Dziegielewski, C. Skead, C. Canturk, T. Webber, C. Fernando, S. M. Thompson, L. H. Foster, M. Ristovic, V. Lawlor, P. G. Chaudhuri, D. Dave, C. Herritt, B. Bush, S. H. Kanji, S. Tanuseputro, P. Thavorn, K. Rosenberg, E. Kyeremanteng, K. Crit Care Res Pract 2021
Opioid Use Increases the Risk of Delirium in Critically Ill Adults Independently of Pain Duprey, M. S. Dijkstra-Kersten, S. M. A. Zaal, I. J. Briesacher, B. A. Saczynski, J. S. Griffith, J. L. Devlin, J. W. Slooter, A. J. C. Am J Respir Crit Care Med 2021

delirium
intensive care
medication
opioid
pain

Association Between Incident Delirium Treatment With Haloperidol and Mortality in Critically Ill Adults uprey, M. S. Devlin, J. W. van der Hoeven, J. G. Pickkers, P. Briesacher, B. A. Saczynski, J. S. Griffith, J. L. van den Boogaard, M. Crit Care Med 2021
Descriptive analysis of the unwarranted continuation of antipsychotics for the management of ICU delirium during transitions of care: A multicenter evaluation across New Jersey Dixit, D. Andrews, L. B. Radparvar, S. Adams, C. Kumar, S. T. Cardinale, M. Am J Health Syst Pharm 2021

ICU delirium
antipsychotics
inappropriate prescribing
intensive care unit
medication safety
transitions of care

Cluster nursing can reduce postoperative delirium and improve the negative emotions and quality of life of elderly ICU patients Di, J. Wang, X. Chen, J. Am J Transl Res 2021

Cluster nursing
delirium
elderly
intensive care unit
quality of life

Cluster nursing can reduce postoperative delirium and improve the negative emotions and quality of life of elderly ICU patients Di, J. Wang, X. Chen, J. Am J Transl Res 2021

Cluster nursing
delirium
elderly
intensive care unit
quality of life

Influence of intraoperative and postoperative factors on the predictive capacity of the delirium risk model for cardiac surgery patients (DELIPRECAS): An observational multicentre study de la Varga-Martínez, O. Gómez-Pesquera, E. Muñoz-Moreno, M. F. Marcos-Vidal, J. M. López-Gómez, A. Rodenas-Gómez, F. Ramasco, F. Álvarez-Refojo, F. Barón, M. S. Tamayo, E. Heredia-Rodríguez, M. Gómez-Sánchez, E. J Clin Anesth 2021

Cardiac Surgical Procedures/adverse effects
Delirium/diagnosis/epidemiology/etiology
Humans
Postoperative Complications/diagnosis/epidemiology/etiology
Risk Factors
Cardiac surgery
Delirium
Prevention

Older trauma patients are at high risk of delirium, especially those with underlying dementia or baseline frailty Ní Chróinín D Francis, N. Wong, P. Kim, Y. D. Nham, S. D'Amours, S. Trauma Surg Acute Care Open 2021

cognition
frailty
geriatrics
patient outcome assessment

The Impact of Monitoring Depth of Anesthesia and Nociception on Postoperative Cognitive Function in Adult Multiple Trauma Patients Cotae, A. M. Ţigliş, M. Cobilinschi, C. Băetu, A. E. Iacob, D. M. Grinţescu, I. M. Medicina (Kaunas) 2021

Adult
Cognition
Delirium
Humans
Middle Aged
Multiple Trauma
Neuropsychological Tests
Nociception
Postoperative Complications
Prospective Studies
Pocd
anesthesia depth
entropy
general emergency surgery

Outcomes of trimodality CROSS regimen in older adults with locally advanced esophageal cancer Cooper, L. Dezube, A. R. De León, L. E. Kucukak, S. Mazzola, E. Dumontier, C. Mamon, H. Enzinger, P. Jaklitsch, M. T. Frain, L. N. Wee, J. O. Eur J Surg Oncol 2021

Cross
Esophageal cancer
Esophagectomy
Neoadjuvant toxicity
Older adults

Nursing intervention to prevent delirium in critically ill adults Contreras, C. C. T. Páez-Esteban, A. N. Rincon-Romero, M. K. Carvajal, R. R. Herrera, M. M. Castillo, Ahdd Rev Esc Enferm USP 2021
Changes in Sedation Practices in Association with Delirium Screening in Infants After Cardiopulmonary Bypass Chomat, M. R. Said, A. S. Mann, J. L. Wallendorf, M. Bickhaus, A. Figueroa, M. Pediatr Cardiol 2021

Cornell Assessment of Pediatric Delirium
Dexmedetomidine
Pediatric cardiac surgery
Pediatric delirium
Sedation
Sedation wean

Risk factors of postoperative delirium after cardiac surgery: a meta-analysis Chen, H. Mo, L. Hu, H. Ou, Y. Luo, J. J Cardiothorac Surg 2021

Age Factors
Cardiac Surgical Procedures/ adverse effects
Carotid Stenosis/epidemiology
Cognitive Dysfunction/epidemiology
Delirium/ etiology
Depression/epidemiology
Diabetes Mellitus/epidemiology
Humans
Intensive Care Units
Length of Stay
Postoperative Complications/etiology
Respiration, Artificial
Risk Factors
Cardiac surgery
Meta-analysis
Postoperative delirium

Diagnosis of overweight or obese malnutrition spells DOOM for hip fracture patients: A prospective audit Bell, J. J. Pulle, R. C. Lee, H. B. Ferrier, R. Crouch, A. Whitehouse, S. L. Clin Nutr 2021

Body mass index
Hip fracture
Malnutrition
Obesity
Overweight

Risk factors for delirium among hospitalized patients in Zambia Mateyo, K. Yan, Y. Liu, D. Zuo, Y. Di Gravio, C. Thome, J. C. Riviello, E. D. Saylor, D. Ely, E. W. Heimburger, D. C. PLoS One 2021
Risk factors associated with treatment of hyperactive postoperative delirium in elderly patients following hip fracture surgery under regional anesthesia: a nationwide population-based study Ahn, E. J. Bang, S. R. Braz J Anesthesiol 2021

Anesthesia
Delirium
Hip fracture

Incidence of delirium in the critical care unit and risk factors in the Central Region, Saudi Arabia Abazid, R. M. Al-Harbi, S. A. Allihimy, A. S. Aldrewesh, D. A. Alkuraydis, S. A. Alhammad, I. M. Elbashir, A. Y. Widyan, A. M. Abohamr, S. I. Saudi Med J 2021

Saudi
critical care
delirium

The risk factors of postoperative delirium in patients with hip fracture: implication for clinical management Xu, W. Ma, H. Li, W. Zhang, C. BMC Musculoskelet Disord 2021

Delirium/diagnosis/epidemiology/etiology
Hip Fractures/epidemiology/surgery
Humans
Incidence
Postoperative Complications/diagnosis/epidemiology/etiology
Risk Factors
Delirium
Hip fracture
Nursing care
Risk
Surgery

Nationwide mortality trends of delirium in Australia and the United States from 2006 to 2016 Wu, H. Mach, J. Le Couteur, D. G. Hilmer, S. N. Australas J Ageing 2021

delirium
geriatrics
mortality
sex differences
trends

The Use of Near-Infrared Spectroscopy and/or Transcranial Doppler as Non-Invasive Markers of Cerebral Perfusion in Adult Sepsis Patients With Delirium: A Systematic Review Wood, M. D. Boyd, J. G. Wood, N. Frank, J. Girard, T. D. Ross-White, A. Chopra, A. Foster, D. Griesdale, D. E. G. J Intensive Care Med 2021

cerebral autoregulation
delirium
near-infrared spectroscopy
pulsatility index
sepsis
transcranial Doppler

Midazolam Premedication Immediately Before Surgery Is Not Associated With Early Postoperative Delirium Wang, M. L. Min, J. Sands, L. P. Leung, J. M. Anesth Analg 2021
The Effect of a Quality Improvement Intervention on Sleep and Delirium in Critically Ill Patients in a Surgical ICU Tonna, J. E. Dalton, A. Presson, A. P. Zhang, C. Colantuoni, E. Lander, K. Howard, S. Beynon, J. Kamdar, B. B. Chest 2021

critical care
delirium
sleep
sleep hygiene
wakefulness

Association between components of the delirium syndrome and outcomes in hospitalised adults: a systematic review and meta-analysis Tieges, Z. Quinn, T. MacKenzie, L. Davis, D. Muniz-Terrera, G. MacLullich, A. M. J. Shenkin, S. D. BMC Geriatr 2021

Cognition
Cognitive Dysfunction
Delirium/diagnosis
Humans
Altered mental status
Arousal
Attention
Delirium
Mortality
Systematic review

The Prognostic Performance of Frailty for Delirium and Functional Decline in Vascular Surgery Patients Thillainadesan, J. Mudge, A. M. Aitken, S. J. Hilmer, S. N. Cullen, J. S. Yumol, M. F. Close, J. C. T. Norris, C. M. Kerdic, R. Naganathan, V. J Am Geriatr Soc 2021

delirium
frailty
function
geriatric surgery

Efficacy of quetiapine for delirium prevention in hospitalized older medical patients: a randomized double-blind controlled trial Thanapluetiwong, S. Ruangritchankul, S. Sriwannopas, O. Chansirikarnjana, S. Ittasakul, P. Ngamkala, T. Sukumalin, L. Charernwat, P. Saranburut, K. Assavapokee, T. BMC Geriatr 2021

Aged
Antipsychotic Agents/adverse effects
Delirium/diagnosis/drug therapy/prevention & control
Double-Blind Method
Haloperidol/therapeutic use
Humans
Quetiapine Fumarate/adverse effects
Thailand
Delirium
Hospitalized
Older
Prevention
Quetiapine

Effects of Slowness, Frailty, Insufficient Intake, and Delirium in Patients Following Cardiac Surgery: A Cohort Study Teng, C. H. Hsu, R. B. Chi, N. H. Wang, S. S. Chen, Y. S. Chen, S. Y. Chen, C. C. J Cardiovasc Nurs 2021
Factors associated with the severity of delirium Tachibana, M. Inada, T. Ichida, M. Kojima, S. Shioya, M. Wakayama, K. Ozaki, N. Hum Psychopharmacol 2021

Drs-r98
benzodiazepine
delirium
severity
β-blocker

Screening for delirium in the intensive care unit using eDIS-ICU - A purpose-designed app: A pilot study Sutt, A. L. Flaws, D. Gunn, H. Eeles, E. Lye, I. Irvine, L. Patterson, S. Bagshaw, T. O'Luanaigh, C. Tronstad, O. Fraser, J. Aust Crit Care 2021

Delirium
Icu
Screening tools
Technology

Association Among Preoperative Cognitive Performance, Regional Cerebral Oxygen Saturation, and Postoperative Delirium in Older Portuguese Patients Susano, M. J. Dias, M. Seixas, F. S. Vide, S. Grasfield, R. Abelha, F. J. Crosby, G. Culley, D. J. Amorim, P. Anesth Analg 2021

Age Factors
Aged
Aged, 80 and over
Blood Gas Monitoring, Transcutaneous
Cerebrovascular Circulation
Cognition
Cognitive Dysfunction/ complications/diagnosis/psychology
Delirium/diagnosis/ etiology/psychology
Elective Surgical Procedures/ adverse effects
Female
Humans
Male
Neuropsychological Tests
Oxygen/ blood
Portugal
Postoperative Complications/diagnosis/ etiology/psychology
Prospective Studies
Risk Assessment
Risk Factors
Spectroscopy, Near-Infrared
Treatment Outcome

Sleep and circadian rhythm disturbances in intensive care unit (ICU)-acquired delirium: a case-control study Sun, T. Sun, Y. Huang, X. Liu, J. Yang, J. Zhang, K. Kong, G. Han, F. Hao, D. Wang, X. J Int Med Res 2021

Adolescent
Adult
Aged
Case-Control Studies
Circadian Rhythm
Delirium/diagnosis
Humans
Intensive Care Units
Middle Aged
Sleep
Young Adult
Delirium
cortisol
critical care
melatonin
polysomnography
sleep

Terminal Delirium in Hospice: The Experiences and Perspectives of Caregivers Providing Care to Terminally Ill Patients in Home Settings Soroka, J. T. Fling, K. J. Heibel, J. M. Kutcher, G. R. Ward, S. J. Am J Hosp Palliat Care 2021

caregivers
delirium experiences
end-of-life care
hospice home care
interventions
terminal delirium

Estimates of Geriatric Delirium Frequency in Noncardiac Surgeries and Its Evaluation Across the Years: A Systematic Review and Meta-analysis Silva, A. R. Regueira, P. Albuquerque, E. Baldeiras, I. Cardoso, A. L. Santana, I. Cerejeira, J. J Am Med Dir Assoc 2021

Delirium
anesthesia
frequency
incidence
noncardiac surgery
old age

The Effects of Bispectral Index-Guided Anesthesia on Postoperative Delirium in Elderly Patients: A Systematic Review and Meta-Analysis Shan, W. Chen, B. Huang, L. Zhou, Y. World Neurosurg 2021

Bispectral index
Elderly patients
Major surgery
Postoperative delirium

Validation of the Delirium Diagnostic Tool-Provisional (DDT-Pro) in a skilled nursing facility and comparison to the 4 'A's test (4AT) Sepúlveda, E. Bermúdez, E. González, D. Cotino, P. Viñuelas, E. Palma, J. Ciutat, M. Grau, I. Vilella, E. Trzepacz, P. T. Franco, J. G. Gen Hosp Psychiatry 2021

Delirium diagnosis
Diagnostic tests comparison.
Geriatric assessment.
Psychiatric status rating scales.
Skilled nursing.

Evaluation of Delirium in Critically Ill Patients Prescribed Melatonin or Ramelteon Romero, N. Dube, K. M. Lupi, K. E. DeGrado, J. R. Ann Pharmacother 2021

agitation
delirium
intensive care unit
melatonin
ramelteon
sedation

Delirium and delirium severity predict the trajectory of the Hierarchical Assessment of Balance and Mobility (HABAM) in hospitalised older people: findings from the DECIDE Study Richardson, S. Murray, J. Davis, D. Stephan, B. C. M. Robinson, L. Brayne, C. Barnes, L. Parker, S. Sayer, A. Dodds, R. Allan, L. J Gerontol A Biol Sci Med Sci 2021

Epidemiology
Hospital related
Physical function

Common biomarkers of physiologic stress and associations with delirium in patients with intracerebral hemorrhage Reznik, M. E. Kalagara, R. Moody, S. Drake, J. Margolis, S. A. Cizginer, S. Mahta, A. Rao, S. S. Stretz, C. Wendell, L. C. Thompson, B. B. Asaad, W. F. Furie, K. L. Jones, R. N. Daiello, L. A. J Crit Care 2021

Biomarkers
Delirium
Intracerebral hemorrhage

Effects of Preoperative Anxiety on Postoperative Delirium in Elderly Patients Undergoing Elective Orthopedic Surgery: A Prospective Observational Cohort Study Ren, A. Zhang, N. Zhu, H. Zhou, K. Cao, Y. Liu, J. Clin Interv Aging 2021

Aged
Aged, 80 and over
Anxiety/ epidemiology
Cohort Studies
Delirium/ epidemiology
Elective Surgical Procedures/ adverse effects
Female
Humans
Logistic Models
Male
Mental Status and Dementia Tests
Odds Ratio
Orthopedic Procedures/ adverse effects
Postoperative Complications/ epidemiology
Prospective Studies
Risk Factors
anxiety
delirium
orthopedic


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