New study shows no effect of low-dose intraoperative ketamine on delirium

Use of low-dose intraoperative ketamine does not lower levels of postoperative pain or reduce delirium in older adults undergoing surgery, according to a new study led by Michael Avidan, MBBCh, Professor of Anesthesiology and Surgery at Washington University St. Louis and NIDUS co-investigator. The findings from this multi-site randomized trial were published online on May 30 […]

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Interaction of Delirium and Dementia on Cognitive Decline

The differences between delirium and dementia can be difficult to spot. If an elderly man with Alzheimer’s disease tends to become confused or agitated in the evening (a condition often known as “sundowning”¹) is his behavior dementia- or delirium-related? Moreover, what are the biological bases that differ between delirium and dementia? New research published in […]