Contributed by Zachary Kunicki, PhD, Assistant Professor of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA; Richard Jones, PhD, Professor of Psychiatry and Human Behavior and Neurology, Warren Alpert Medical School of Brown University, Providence, RI, USA; and Sharon Inouye, MD MPH, Milton and Shirley F. Levy Family Chair […]
Category Archives: AD/ADRD
Posts that mention Alzheimer’s Disease or related dementias
Postoperative Delirium and Biomarkers of Alzheimer’s Disease: What We Know and What We Need to Know
Contributed by Dr. Sophia Wang, MD, MS, Assistant Professor of Clinical Psychiatry, Indiana University School of Medicine Postoperative delirium affects 15-50% of older adults undergoing major surgery.1 The literature strongly supports a bidirectional relationship between delirium and dementia.2 While both delirium and dementia affect cognition, they are quite different in their clinical presentations. Delirium is […]
Association between Symptom Domains of Delirium and Outcomes in Hospitalised Adults
Contributed by Zoë Tieges, PhD, Psychology Research Fellow, Geriatric Medicine, Usher Institute, The University of Edinburgh, Edinburgh, UK Research question: do patients with delirium experience poorer outcomes when they have certain symptoms? Delirium is a syndrome with a wide spectrum of clinical presentations. According to DSM-5 (and the recent DSM-5 Text Revision) criteria, the key […]
Frailty, Postoperative Delirium and Cognitive Dysfunction: Where is the Association?
Contributed by Elizabeth Mahanna-Gabrielli, MD Department of Anesthesiology, Miller School of Medicine, University of Miami, Miami, Florida As a neuroanesthesiologist and intensivist, I’ve seen many frail patients come into the operating room and intensive care unit. During the early years of my career, frailty was informally defined as patient who was elderly, weak, and deconditioned; clinicians […]