What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Comprehensive signal detection of delirium-associated medication using the Food and Drug Administration Adverse Event Reporting System
- Authors
- Hatano, M. Sogawa, R. Shin, K. Esumi, S. Ishikawa, A. Mizumura, R. Araki, H. Yamada, S.
- Year
- 2024
- Journal
- Gen Hosp Psychiatry
- Abstract
OBJECTIVE: Several medications are associated with delirium; however, studies with adequate statistical power are limited, and it is difficult to determine the effects of the various concomitant medications used in clinical practice. Therefore, in this study, we aimed to comprehensively evaluate the safety signals of delirium-associated drugs using a spontaneous adverse event reporting system. METHOD: The JAPIC AERS (Food and Drug Administration Adverse Event Reporting System pre-processed by the Japan Pharmaceutical Information Center) was used for the analysis in this pharmacovigilance study. The reporting odds ratio (ROR) for delirium was adjusted for using multivariate logistic regression analysis with sex, age, indication, and melatonin receptor agonist use, and 22 drug categories were targeted as covariates. RESULTS: After excluding patients with missing information, 7,527,568 patients were included in the study. Delirium signals were detected even after adjusting for covariates in 17 drug categories, including benzodiazepines (adjusted ROR, 1.76; 95% confidence interval [CI], 1.64-1.89), opioids (adjusted ROR, 4.42; 95% CI, 4.21-4.64), and tricyclic antidepressants (adjusted ROR, 2.44; 95% CI, 2.20-2.71). CONCLUSIONS: These findings suggest that many drug classes, such as benzodiazepines, are independent risk factors for delirium and strengthen the evidence of an association between delirium and medications.
- PMID
PMID: 38941744
- Keywords
Humans
*Delirium/chemically induced/epidemiology
*Adverse Drug Reaction Reporting Systems/statistics & numerical data
Male
Female
United States
Aged
Middle Aged
*Pharmacovigilance
Adult
*United States Food and Drug Administration
Japan/epidemiology
Aged, 80 and over
Benzodiazepines/adverse effects
Analgesics, Opioid/adverse effects
Adverse drug reaction reporting systems
Benzodiazepines
Cholinergic antagonists
Delirium
Signal detection
Spontaneous reporting databases
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Efficacy of haloperidol to decrease the burden of delirium in adult critically ill patients: the EuRIDICE randomized clinical trial | Smit, L. Slooter, A. J. C. Devlin, J. W. Trogrlic, Z. Hunfeld, N. G. M. Osse, R. J. Ponssen, H. H. Brouwers, Ajbw Schoonderbeek, J. F. Simons, K. S. van den Boogaard, M. Lens, J. A. Boer, D. P. Gommers, Dampj Rietdijk, W. J. R. van der Jagt, M. | Crit Care | 2023 |
Adult |
| Efficacy of haloperidol to decrease the burden of delirium in adult critically ill patients: the EuRIDICE randomized clinical trial | Smit, L. Slooter, A. J. C. Devlin, J. W. Trogrlic, Z. Hunfeld, N. G. M. Osse, R. J. Ponssen, H. H. Brouwers, Ajbw Schoonderbeek, J. F. Simons, K. S. van den Boogaard, M. Lens, J. A. Boer, D. P. Gommers, Dampj Rietdijk, W. J. R. van der Jagt, M. | Crit Care | 2023 |
Adult |
| Effectiveness of a Multi-component Delirium Prevention Program Implemented on General Medicine Hospital Units: an Interrupted Time Series Analysis | Versloot, J. Minotti, S. C. Amer, S. Ali, A. Ma, J. Peters, M. L. Saab, H. Tang, T. Kerr, J. Reid, R. | J Gen Intern Med | 2023 |
Adult, Humans, Aged, Aged, 80 and over, Interrupted Time Series Analysis, Retrospective Studies, *Delirium/diagnosis/epidemiology/prevention & control, Hospitals, Community, Ontario, Hospital Units, delirium prevention, delirium program, inpatients, internal medicine |
| Delirium During Critical Illness and Subsequent Change of Treatment in Patients With Cancer: A Mediation Analysis | Vizzacchi, B. A. Dettino, A. L. A. Besen, Bamp Caruso, P. Nassar, A. P., Jr. | Crit Care Med | 2023 |
IUC, delirium, cohort, cancer, CAM |
| Efficacy and moderators of prevention and treatment of delirium with melatonin receptor agonists: A systematic review and meta-analysis of randomized controlled trials | Wada, M. Yasuda, H. Nakajima, S. Etani, T. Miura, A. Asada, S. Yoshida, K. Noda, Y. Takeuchi, H. | Gen Hosp Psychiatry | 2023 |
Delirium |
| Intraoperative body temperature and emergence delirium in elderly patients after non-cardiac surgery: A secondary analysis of a prospective observational study | Wang, G. He, S. Yu, M. Zhang, Y. Mu, D. Wang, D. | Chin Med J (Engl) | 2023 |
Humans |
| Relationship between preoperative neutrophil-to-lymphocyte ratio and postoperative delirium: The PNDABLE and the PNDRFAP cohort studies | Wu, X. Chi, F. Wang, B. Liu, S. Wang, F. Wang, J. Tang, X. Bi, Y. Lin, X. Li, J. | Brain Behav | 2023 |
Alzheimer-related biomarkers |
| Risk Factors for Delirium Superimposed on Dementia in Elderly Patients in Comprehensive Ward | Xiao, Q. Zhang, S. Li, C. Zhu, Y. | Am J Alzheimers Dis Other Demen | 2023 |
Humans |
| Effect of postoperative delirium after cardiovascular surgery on 5-year mortality | Yokoyama, C. Yoshitnai, K. Ogata, S. Fukushima, S. Matsuda, H. | JA Clin Rep | 2023 |
5-year mortality, Cardiopulmonary bypass, Cardiovascular surgery, Postoperative delirium |
| Association Between the Use of Midazolam During Cardiac Anesthesia and the Incidence of Postoperative Delirium: A Retrospective Cohort Study Using a Nationwide Database | Yoshimura, M. Hidaka, Y. Morimoto, Y. | J Cardiothorac Vasc Anesth | 2023 |
Humans, *Emergence Delirium/epidemiology, Midazolam/adverse effects, Retrospective Studies, Incidence, Postoperative Nausea and, Vomiting/chemically induced/epidemiology, *Anesthesia, Cardiac Procedures, Postoperative, Complications/chemically induced/epidemiology, Diagnosis Procedure, Combination data, cardiac surgery, midazolam, postoperative delirium, stabilized inverse probability of treatment |
| Associations of Delirium to Posthospital Outcomes After Acute Stroke: A Scoping Review | Young, B. C. Rhoten, B. A. | J Neurosci Nurs | 2023 |
Adult, Humans, Adolescent, *Dexmedetomidine/therapeutic use, Palliative Care, *Pain, Intractable/drug therapy/chemically induced, Hypnotics and, Sedatives/therapeutic use, Retrospective Studies, *Delirium/drug therapy, Intensive Care Units |
| Dexmedetomidine use for patients in palliative care with intractable pain and delirium: A retrospective study | Yu, S. Y. Schellenberg, J. Alleyne, A. | PLoS One | 2023 |
Adult, Humans, Adolescent, *Dexmedetomidine/therapeutic use, Palliative Care, *Pain, Intractable/drug therapy/chemically induced, Hypnotics and, Sedatives/therapeutic use, Retrospective Studies, *Delirium/drug therapy, Intensive Care Units |
| Validity and predictability of the confusion assessment method for the intensive care unit for delirium among critically ill patients in the intensive care unit: A systematic review and meta-analysis | Zhang, Y. Diao, D. Zhang, H. Gao, Y. | Nurs Crit Care | 2023 |
Cam-icu, critical, delirium, intensive care unit |
| Impact of nursing interventions on discharge disposition in patients with postoperative delirium | Zhao, Y. Quon, A. Luke, K. Tivis, L. J. | Nursing | 2023 |
Humans, Aged, Patient Discharge, Retrospective Studies, *Emergence Delirium, *Hypoalbuminemia, Hospitalization |
| Causal relationships between delirium and Alzheimer's disease: a bidirectional two-sample Mendelian randomization study | Zheng, J. Du, X. Yang, L. Fu, H. | Eur J Med Res | 2023 |
Humans, *Alzheimer Disease/genetics, Genome-Wide Association Study, Mendelian Randomization Analysis, Risk Factors, Nonoxynol, Alzheimer’s disease, Causal relationships, Delirium, European, Mendelian randomization |
| Circadian rhythm disturbance and delirium in ICU patients: a prospective cohort study | Li, J. Cai, S. Liu, X. Mei, J. Pan, W. Zhong, M. Zhang, Y. | Medicine (Baltimore) | 2023 |
United States, Humans, *Hydrocortisone, *Melatonin, Prospective Studies, Circadian Rhythm, Intensive Care Units, Cortisol, Delirium, Melatonin |
| Amantadine-associated delirium in patients with maintenance dialysis: Insomnia-associated recovery and uneven seasonal distribution | Li, J. Si, B. Chao, J. He, J. | Medicine (Baltimore) | 2023 |
Humans, Renal Dialysis, Retrospective Studies, Seasons, *Sleep Initiation and Maintenance Disorders/drug therapy, Amantadine/adverse effects, *Delirium/chemically induced/epidemiology |
| Effects of Different Injection Rates of Propofol on Postoperative Cognition in Elderly Patients Undergoing Laparoscopic Inguinal Hernia Repair | Li, T. Han, W. Yang, X. Wang, Y. Peng, L. He, L. Hu, L. Liu, J. Xia, M. Wang, S. | Drug Des Devel Ther | 2023 |
Humans, Aged, *Propofol/adverse effects, Anesthetics, Intravenous/adverse effects, *Hernia, Inguinal/surgery/chemically induced, Postoperative, Complications/epidemiology, Cognition, *Delirium, *Laparoscopy, bispectral index, burst suppression, elderly, injection rate, postoperative cognitive decline, propofol |
| The Effect of Music as a Non-Pharmacological Intervention on the Physiological, Psychological, and Social Response of Patients in an Intensive Care Unit | Lorek, M. Bąk, D. Kwiecień-Jaguś, K. Mędrzycka-Dąbrowska, W. | Healthcare (Basel) | 2023 |
classical music, delirium, intensive care unit, music perception, music therapy, nursing, pain, therapeutic music listening |
| Feasibility of a Modified Otago Exercise Program for Older Adults With Cognitive Vulnerability | Mangione, K. K. Darreff, H. Welsh, M. Ni, W. Wolff, E. Booth, J. T. Glenney, S. S. Fortinsky, R. H. | J Appl Gerontol | 2023 |
Humans, Aged, Exercise Therapy, Feasibility Studies, Postural Balance, *Dementia/therapy, Cognition, *Delirium, Otago exercise program, dementia, depression, exercise, feasibility, older adult |
| Accuracy of Delirium Screening Tools in Older People with Cancer-A Systematic Review | Martínez-Arnau, F. M. Puchades-García, A. Pérez-Ros, P. | Cancers (Basel) | 2023 |
accuracy, aged, assessment, cancer, delirium, incidence, prevalence, psychometric properties |
| Evaluation of the delirium preventive effect of dual orexin receptor antagonist (DORA) in critically ill adult patients requiring ventilation with tracheal intubation at an advanced emergency center: A single-center, retrospective, observational study | Matsuoka, A. Sogawa, R. Murakawa-Hirachi, T. Mizoguchi, Y. Monji, A. Shimanoe, C. Shinada, K. Koami, H. Sakamoto, Y. | J Alzheimers Dis | 2023 |
Humans, Adult, Adolescent, *Orexin Receptor Antagonists/adverse effects, Retrospective Studies, Critical Illness/therapy, *Delirium/prevention & control/epidemiology, Intubation, Intratracheal, Delirium, Intensive care unit, Lemborexant, Sleep disorder, Suvorexant |
| Individualized Summary Assessment of Detailed Neuropsychological Testing for the Etiological Diagnosis of Newly Detected Cognitive Impairment in Hospitalized Geriatric Patients | Mäurer, A. Himmel, G. Lange, C. Mathies, F. Apostolova, I. Peters, O. Buchert, R. | J Alzheimers Dis | 2023 |
Alzheimer’s disease, delirium, dementia, etiological diagnosis, hospitalized, geriatric patients, neuropsychological testing |
| A systematic review of studies reporting on neuropsychological and functional domains used for assessment of recovery from delirium in acute hospital patients | McCartney, H. Noble, E. MacLullich, A. M. J. Davis, D. H. J. Evans, J. Shenkin, S. D. Muniz-Terrera, G. Sandeman, D. Tieges, Z. | Int J Geriatr Psychiatry | 2023 |
Humans, *Activities of Daily Living, *Delirium/diagnosis/drug therapy |
| Implementing a ward-based programme to improve care for older inpatients: process evaluation of the cluster randomised CHERISH trial | Mudge, A. M. McRae, P. Young, A. Blackberry, I. Lee-Steere, K. Barrimore, S. Quirke, T. Harvey, G. | BMC Health Serv Res | 2023 |
Aged, Humans, *Delirium/prevention & control, Hospitals, *Inpatients, Nutritional Status, Prospective Studies, Age-friendly hospitals, Delirium, Evaluation, Facilitation, Implementation |
| Effect of laparoscopic liver resection on postoperative delirium in elderly patients with hepatocellular carcinoma | Nomi, T. Kaibori, M. Hirokawa, F. Ueno, M. Hokuto, D. Noda, T. Nakai, T. Ikoma, H. Iida, H. Kubo, S. | J Hepatobiliary Pancreat Sci | 2023 |
elderly patients, hepatocellular carcinoma, laparoscopic liver resection, postoperative delirium |
| Development of a scale measuring the difficulties faced by nurses who care for patients with delirium in intensive care units | Owaki, N. Tanaka, M. Kawakami, A. | Aust Crit Care | 2023 |
Humans, Reproducibility of Results, Pilot Projects, Intensive Care Units, Surveys and Questionnaires, *Delirium, *Nurses, Psychometrics/methods, Delirium, Exploratory factor analysis, Nurse, Psychological distress, Scale development |
| Preliminary evaluation of a smartphone application (DelApp) for identification of delirium in sub-Saharan Africa | Paddick, S. M. Gamassa, E. Mwaluwinga, N. Lewis, G. Duinmaijer, A. Urasa, S. Tucker, L. Mukaetova-Ladinska, E. B. Cosker, G. Dekker, M. Kisoli, A. Cletus, J. Lissu, C. Dotchin, C. Gray, W. K. Walker, R. | Acta Neuropsychiatr | 2023 |
Africa, cognitive assessment, delirium, screening |
| Postoperative delirium after cholecystectomy in older patients: A retrospective study | Park, Y. M. Seo, H. I. Noh, B. G. Kim, S. Hong, S. B. Lee, N. K. Kim, D. U. Han, S. Y. | Ann Hepatobiliary Pancreat Surg | 2023 |
Body mass index, Cholecystectomy, Delirium, Nutrition, Older patients |
| Exploring the Documentation of Delirium in Patients After Cardiac Surgery: A Retrospective Patient Record Study | Poikajärvi, S. Peltonen, L. M. Siirala, E. Heimonen, J. Moen, H. Salanterä, S. Junttila, K. | Comput Inform Nurs | 2023 |
delirium, cardiac, surgery, EHR, documentation |
| The Efficacy of Low-Dose Risperidone Treatment for Post-Surgical Delirium in Elderly Orthopedic Patients | Raphael, L. Edna, E. Irina, K. Oded, H. | Medicina (Kaunas) | 2023 |
Female, Humans, Aged, Aged, 80 and over, Male, Risperidone/adverse effects, Prospective Studies, *Delirium/drug therapy/etiology/diagnosis, *Orthopedics, Postoperative Complications/drug therapy, delirium, elderly, post-surgical, protocol, risperidone |
| Serum Biomarkers of a Pro-Neuroinflammatory State May Define the Pre-Operative Risk for Postoperative Delirium in Spine Surgery | Ruhnau, J. Müller, J. Nowak, S. Strack, S. Sperlich, D. Pohl, A. Dilz, J. Saar, A. Veser, Y. Behr, F. Rehberg, S. Usichenko, T. Hahnenkamp, K. Ehler, J. Flöel, A. Schroeder, H. W. S. Müller, J. U. Fleischmann, R. Vogelgesang, A. | Int J Mol Sci | 2023 |
Humans, Aged, *Emergence Delirium, Interleukin-6/metabolism, *Delirium/diagnosis/etiology, Gasdermins, Postoperative, Complications/etiology, Prospective Studies, Biomarkers/metabolism, Gasdermin D, biomarker, postoperative cognitive dysfunction, postoperative delirium, sTREM2, spine surgery |
| Effects of an interactive handgrip game on surgical patients requiring intensive care: An assessor-blinded randomized controlled trial | Han, P. H. Shih, C. Y. Wang, A. Y. Chen, Y. C. Yang, C. C. Fan, Y. C. Hsiang, H. F. Chiu, H. Y. | Intensive Crit Care Nurs | 2023 |
Critically ill patients, Handgrip strength, Interactive handgrip game, Psychological distress |
| A critical appraisal and recommendation synthesis of delirium clinical practice guidelines relevant to the care of older adults in the emergency department: An umbrella review | Filiatreault, S. Grimshaw, J. M. Kreindler, S. A. Chochinov, A. Linton, J. Chatterjee, R. Azeez, R. Doupe, M. B. | J Eval Clin Pract | 2023 |
Agree, aged, delirium, emergency services (hospital), practice guideline, systematic review |
| Implementation of a novel nursing assessment tool in geriatric trauma patients with proximal femur fractures | Berk, T. Thalmann, M. Jensen, K. O. Schwarzenberg, P. Jukema, G. N. Pape, H. C. Halvachizadeh, S. | PLoS One | 2023 |
Humans, Aged, Retrospective Studies, *Proximal Femoral Fractures, *Delirium/etiology/complications, Risk Factors, Nutritional Status, Geriatric Assessment |
| Enhanced recovery after surgery in patients with normal pressure hydrocephalus undergoing ventriculoperitoneal shunting procedures | Ali, A. Gupta, B. Johansen, P. Santiago, R. B. Dabecco, R. Mandel, M. Adada, B. Botero, J. Roy, M. Borghei-Razavi, H. | Clin Neurol Neurosurg | 2023 |
Humans, Ventriculoperitoneal Shunt/adverse effects, *Hydrocephalus, Normal Pressure/surgery/complications, *Enhanced Recovery After Surgery, Postoperative Complications/etiology, *Delirium/complications/surgery, Length of Stay, Retrospective Studies, Delirium, Eras, Neurosurgery, Normal pressure hydrocephalus, Ventriculoperitoneal shunting |
| The use of patient sitters at a Swiss hospital: A retrospective observational study | Kramer, I. Schubert, M. | PLoS One | 2023 |
Aged, Humans, Confusion, *Ethnicity, Hospitals, *Inpatients, Retrospective Studies, Switzerland, Aged, 80 and over |
| The role of inflammatory parameters in the prediction of postoperative delirium in patients undergoing coronary artery bypass grafting | Şaşkin, H. Özcan, K. S. Yildirim, S. | Cardiovasc J Afr | 2023 |
Humans, *Emergence Delirium/etiology, Retrospective Studies, Postoperative Complications/diagnosis/etiology, Coronary Artery Bypass/adverse effects, Risk Factors, coronary artery bypass grafting surgery, delirium, inflammation |
| Opioids increase the risk of delirium in critically ill patients: A propensity score analysis | Shi, H. J. Zhang, X. P. Hai, C. Shi, W. Wang, P. Hu, A. M. | Int J Clin Pharmacol Ther | 2023 |
Humans, *Analgesics, Opioid/adverse effects, Intensive Care Units, Critical, Illness/therapy, Propensity Score, Risk Factors, *Delirium/chemically induced/diagnosis/epidemiology |
| Characteristics of delirium and its association with sedation and in-hospital mortality in patients with COVID-19 on veno-venous extracorporeal membrane oxygenation | Sun, P. Y. Fanning, J. Peeler, A. Shou, B. Lindsley, J. Caturegli, G. Whitman, G. Cha, S. Kim, B. S. Cho, S. M. | Front Med (Lausanne) | 2023 |
analgesia, deep sedation, delirium, extracorporeal membrane oxygenation, hospital mortality |
| Delirium as a Risk Factor for Mortality in Critically Ill Patients With Cancer | Tao, J. Seier, K. Marasigan-Stone, C. B. Simondac, J. S. Pascual, A. V. Kostelecky, N. T. SantaTeresa, E. Nwogugu, S. O. Yang, J. J. Schmeltz, J. Tan, K. S. Chawla, S. Voigt, L. P. | JCO Oncol Pract | 2023 |
Humans, Female, Middle Aged, Aged, Male, *Delirium/diagnosis/prevention & control, Critical Illness, Risk Factors, Intensive Care Units, *Neoplasms |
| Effectiveness of sleep interventions to reduce delirium in critically ill patients: A systematic review and meta-analysis | Teng, J. Qin, H. Guo, W. Liu, J. Sun, J. Zhang, Z. | J Crit Care | 2023 |
Critical illness, Delirium, ICUs, Meta-analysis, Sleep |
| Chlorpromazine's Potential Role in Palliating Distressing Symptoms Associated With Hyperactive Delirium in Patients at End of Life | Tiefenthaler, C. M. Hirst, J. M. Edmonds, K. P. Atayee, R. S. | J Palliat Med | 2023 |
Humans, Chlorpromazine/therapeutic use, Psychomotor Agitation/drug therapy/complications/prevention & control, *Delirium/drug therapy, *Neoplasms/complications, Death, Palliative Care, chlorpromazine |
| Delirium and IL-6 added to clinical scores improves their performance: a prospective analysis of CALL, PREDI-CO, MRS score applied to a population of patients admitted to internal medicine ward | Vannucchi, V. Pelagatti, L. Barone, F. Bertini, L. Celli, T. Boccia, N. Veneziani, F. Cimolato, B. Landini, G. | Intern Emerg Med | 2023 |
Call, Covid-19, Delirium,il-6, Mrs, Outcome, Predi-co, Score |
| Electroencephalographic Biomarkers, Cerebral Oximetry, and Postoperative Cognitive Function in Adult Non-Cardiac Surgical Patients: a Prospective Cohort Study | Vlisides, P. E. Li, D. Maywood, M. Zierau, M. Lapointe, A. P. Brooks, J. McKinney, A. M. Leis, A. M. Mentz, G. Mashour, G. A. | Anesthesiology | 2023 |
Adult, Humans, Retrospective Studies, Prospective Studies, *Delirium/diagnosis/epidemiology/etiology, Critical Illness, Intensive Care Units, Critically ill, Delirium, Intensive care unit, Machine learning, Prediction |
| Early prediction of delirium upon intensive care unit admission: Model development, validation, and deployment | Wang, M. L. Kuo, Y. T. Kuo, L. C. Liang, H. P. Cheng, Y. W. Yeh, Y. C. Tsai, M. T. Chan, W. S. Chiu, C. T. Chao, A. Chou, N. K. Yeh, Y. C. Ku, S. C. | J Clin Anesth | 2023 |
Adult, Humans, Retrospective Studies, Prospective Studies, *Delirium/diagnosis/epidemiology/etiology, Critical Illness, Intensive Care Units, Critically ill, Delirium, Intensive care unit, Machine learning, Prediction |
| Perioperative cerebral perfusion in aortic arch surgery: a potential link with neurological outcome | Weijs, R. W. J. Tromp, S. C. Heijmen, R. H. Seeber, A. A. van Belle-van Haaren, Njcw Claassen, Jahr Thijssen, D. H. J. | Eur J Cardiothorac Surg | 2023 |
Humans, Aorta, Thoracic/diagnostic imaging/surgery, *Brain Ischemia/etiology/prevention & control, Retrospective Studies, *Stroke/etiology/prevention & control, Perfusion, *Ischemic Stroke, Cerebrovascular Circulation/physiology, *Delirium, Treatment Outcome, Postoperative Complications/prevention & control, *Aortic Aneurysm, Thoracic/surgery, Antegrade selective cerebral perfusion, Aortic surgery, Cerebral circulation, Perioperative management, Postoperative complication, Thoracic aorta |
| Preoperative Cognitive Impairment and Postoperative Delirium in Elderly Surgical Patients: A Retrospective Large Cohort Study (The CIPOD Study) | Weiss, Y. Zac, L. Refaeli, E. Ben-Yishai, S. Zegerman, A. Cohen, B. Matot, I. | Ann Surg | 2023 |
Humans, Aged, *Emergence Delirium/complications, *Delirium/diagnosis/epidemiology/etiology, Retrospective Studies, Cohort Studies, Prospective Studies, *Cognitive Dysfunction/diagnosis/epidemiology, Postoperative Complications/etiology, Risk Factors |
| Contribution of Different Brain Disorders and Multimorbidity to Delirium Superimposed Dementia (DSD) | Wetterling, T. Junghanns, K. | Geriatrics (Basel) | 2023 |
brain infarction, deliriumm dementia, multimorbidity, white matter hyperintensities |
| Prevalence and Risk Factors for Intensive Care Unit Delirium After Traumatic Brain Injury: A Retrospective Cohort Study | Wilson, L. D. Maiga, A. W. Lombardo, S. Nordness, M. F. Haddad, D. N. Rakhit, S. Smith, L. F. Rivera, E. L. Cook, M. R. Thompson, J. L. Raman, R. Patel, M. B. | Neurocrit Care | 2023 |
Adult, Humans, Retrospective Studies, Prevalence, *Brain Injuries,, Traumatic/complications/epidemiology, Risk Factors, Intensive Care Units, *Subarachnoid Hemorrhage/complications, *Delirium/epidemiology/etiology, Glasgow Coma Scale,Critical illness, Delirium, Mental status, Predictors, Traumatic brain injury |
| Moderate-to-high risk of obstructive sleep apnea with excessive daytime sleepiness is associated with postoperative neurocognitive disorders: a prospective one-year follow-up cohort study | Wu, W. Pu, L. Hu, X. Chen, Q. Wang, G. Wang, Y. | Front Neurosci | 2023 |
excessive daytime sleepiness, obstructive sleep apnea, older adults, perioperative neurocognitive disorders, surgery |
| Effect of Dexmedetomidine on Posttraumatic Stress Disorder in Patients Undergoing Emergency Trauma Surgery: A Randomized Clinical Trial | Yu, Y. Li, Y. Han, D. Gong, C. Wang, L. Li, B. Yao, R. Zhu, Y. | JAMA Netw Open | 2023 |
Male, Humans, Adult, *Dexmedetomidine/therapeutic use/adverse effects, *Stress Disorders, Post-Traumatic/epidemiology/prevention & control, Saline Solution, *Emergence Delirium/chemically induced, Administration, Intravenous |
| Regional versus general anesthesia in older patients for hip fracture surgery: a systematic review and meta-analysis of randomized controlled trials | Zhou, S. L. Zhang, S. Y. Si, H. B. Shen, B. | J Orthop Surg Res | 2023 |
Humans, Aged, Randomized Controlled Trials as Topic, *Hip Fractures/surgery, Anesthesia, General/adverse effects, *Plastic Surgery Procedures, *Delirium, Anesthesia, General, Hip fracture, Meta-analysis, Regional |
| Delirium in Medically Hospitalized Patients: Prevalence, Recognition and Risk Factors: A Prospective Cohort Study | Al Farsi, R. S. Al Alawi, A. M. Al Huraizi, A. R. Al-Saadi, T. Al-Hamadani, N. Al Zeedy, K. Al-Maqbali, J. S. | J Clin Med | 2023 |
delirium, elderly, incidence, prevalence, risk factors |
| Delirium detection using wearable sensors and machine learning in patients with intracerebral hemorrhage | Ahmed, A. Garcia-Agundez, A. Petrovic, I. Radaei, F. Fife, J. Zhou, J. Karas, H. Moody, S. Drake, J. Jones, R. N. Eickhoff, C. Reznik, M. E. | Front Neurol | 2023 |
actigraphy, delirium, intracerebral hemorrhage, machine learning, neurocritical care, stroke, wearable electronic devices |
| Associations of postoperative delirium with activities of daily living in older people after major surgery: A prospective cohort study | Aldwikat, R. K. Manias, E. Holmes, A. C. Tomlinson, E. Nicholson, P. | J Clin Nurs | 2023 |
activities of daily living, cognition, older surgical patients, post-anaesthetic care unit, postoperative delirium |
| Association Between Risk of Stroke and Delirium After Cardiac Surgery and a New Electroencephalogram Index of Interhemispheric Similarity | Baron Shahaf, D. Hight, D. Kaiser, H. Shahaf, G. | J Cardiothorac Vasc Anesth | 2023 |
Eeg, Lir, delirium, stroke |
| Melatonin and Ramelteon for the treatment of delirium: A systematic review and meta-analysis | Beaucage-Charron, J. Rinfret, J. Coveney, R. Williamson, D. | J Psychosom Res | 2023 |
Humans, Aged, *Melatonin/therapeutic use, *Delirium/drug therapy, *Indenes/therapeutic use, *Antipsychotic Agents/therapeutic use, Delirium, Melatonergic agonist, Melatonin, Ramelteon, Treatment |
| A Core Outcome Set for Interventions to Prevent and/or Treat Delirium in Palliative Care | Bryans, A. Siddiqi, N. Burry, L. Clarke, M. Koffman, J. Agar, M. R. Rose, L. | J Pain Symptom Manage | 2023 |
Delirium, clinical trials, core outcome set, palliative care |
| Delirium in the Era of COVID-19 | Byrnes, T. Pate, K. Cochran, A. R. Belin, L. | J Nurs Care Qual | 2023 |
delirium, covid-19, older adults, |
| Leveraging the Electronic Health Record to Implement Emergency Department Delirium Screening | Chary, A. N. Brickhouse, E. Torres, B. Santangelo, I. Carpenter, C. R. Liu, S. W. Godwin, K. M. Naik, A. D. Singh, H. Kennedy, M. | Appl Clin Inform | 2023 |
Humans, Aged, *Electronic Health Records, Emergency Service, Hospital, Attitude of Health Personnel, *Delirium/diagnosis |
| Cigarette smoking is linked to an increased risk of delirium following arthroplasty in patients suffering from osteoarthritic pain | Chen, J. R. Chen, J. Q. Hu, J. C. Huang, R. S. Shen, L. Gu, H. Chai, X. Q. Wang, D. | CNS Neurosci Ther | 2023 |
osteoarthritis, postoperative delirium, smoking, total knee arthroplasty |
| Neurological Examination Frequency and Time-to-Delirium After Traumatic Brain Injury | Chotai, S. Chen, J. W. Turer, R. Smith, C. Kelly, P. D. Bhamidipati, A. Davis, P. McCarthy, J. T. Bendfeldt, G. A. Peyton, M. B. Dennis, B. M. Terry, D. P. Guillamondegui, O. Yengo-Kahn, A. M. | Neurosurgery | Neurological Examination Frequency and Time-to-Delirium After Traumatic Brain Injury |
neurological, traumatic brain injury, delirium, time-to-delirium, ICU, CAM-ICU |
| Effect of inhaled anaesthetics on cognitive and psychiatric outcomes in critically ill adults: a systematic review and meta-analysis | Cuninghame, S. Jerath, A. Gorsky, K. Sivajohan, A. Francoeur, C. Withington, D. Burry, L. Cuthbertson, B. H. Orser, B. A. Martin, C. Owen, A. M. Slessarev, M. | Br J Anaesth | 2023 |
cognition, critical care medicine, delirium, post-ICU syndrome, psychiatric, sedation |
| The Delirium Interview as a new reference standard in studies on delirium assessment tools | Ditzel, F. L. Slooter, A. J. C. van den Boogaard, M. Boonstra, M. van Nesselrooij, T. A. Kromkamp, M. Pop-Purceleanu, M. Rood, P. J. T. Osse, R. J. Chan, C. K. MacLullich, A. M. J. Tieges, Z. Neufeld, K. J. Hut, S. C. A. | J Am Geriatr Soc | 2023 |
Humans, Male, Aged, Aged, 80 and over, Female, Prospective Studies, *Intensive Care Units, *Delirium/diagnosis, Critical Care, Reference Standards, cognitive assessment, delirium, neuropsychological tests, reference standard |
| Development and validation of an international preoperative risk assessment model for postoperative delirium | Dodsworth, B. T. Reeve, K. Falco, L. Hueting, T. Sadeghirad, B. Mbuagbaw, L. Goettel, N. Schmutz Gelsomino, N. | Age Ageing | 2023 |
Humans, Aged, *Emergence Delirium/complications, *Delirium/diagnosis/etiology/prevention & control, Risk Factors, Postoperative Complications/diagnosis/etiology/prevention & control, Risk Assessment, C-Reactive Protein, algorithm, clinical practice, older people, postoperative delirium, risk prediction |
| Emergency Department Length of Stay Is Associated with Delirium in Older Adults | Elder, N. M. Mumma, B. E. Maeda, M. Y. Tancredi, D. J. Tyler, K. R. | West J Emerg Med | 2023 |
Humans, Female, Aged, Male, Length of Stay, Retrospective Studies, *Delirium/epidemiology, Prospective Studies, Risk Factors, Emergency Service, Hospital, *Dementia |
| 'It's tough. It is hard': A qualitative interview study of staff and volunteers caring for hospice in-patients with delirium | Featherstone, I. Siddiqi, N. Jones, L. Coppo, E. Sheldon, T. Hosie, A. Wolkowski, A. Bush, S. H. Taylor, J. Teodorczuk, A. Johnson, M. J. | Palliat Med | 2023 |
Humans, *Hospices, Palliative Care/psychology, *Hospice Care, Qualitative Research, Volunteers, *Delirium/therapy, Delirium, hospices, palliative care, psychological distress, qualitative research |
| Metabolic syndrome and the risk of postoperative delirium and postoperative cognitive dysfunction: a multi-centre cohort study | Feinkohl, I. Janke, J. Slooter, A. J. C. Winterer, G. Spies, C. Pischon, T. | Br J Anaesth | 2023 |
cholesterol, epidemiology, metabolic syndrome, obesity, postoperative cognitive dysfunction, postoperative delirium |
| Delirium After Traumatic Brain Injury: Prediction by Location and Size of Brain Lesion | Han, S. J. Suh, J. H. Lee, J. Y. Kim, S. J. | Ann Rehabil Med | 2023 |
Delirium, Intracranial hemorrhages, Traumatic brain injury |
| Meta-analysis of the effect of entropy-assisted general anesthesia on the quality of postoperative recovery | He, B. Zhang, N. Peng, M. | Medicine (Baltimore) | 2023 |
Humans, Postoperative Nausea and Vomiting/epidemiology/prevention & control, *Emergence Delirium, Entropy, *Intraoperative Awareness, Anesthesia, General/adverse effects, Randomized Controlled Trials as Topic |
| Sex-specific clinical characteristics and treatment responses in delirium management: findings from a prospective cohort study in elderly patients | Hildenbrand, F. F. Boettger, S. Spiller, T. Schubert, M. Ernst, J. von Känel, R. Zipser, C. M. | Int Clin Psychopharmacol | 2023 |
delirium, incidence, sex differences, observational, elderly |
| A predictive scoring system for postoperative delirium in the elderly patients with intertrochanteric fracture | Hu, Y. Yang, M. | BMC Surg | 2023 |
Humans, Aged, Infant, Retrospective Studies, *Emergence Delirium/etiology, *Fracture Fixation, Intramedullary/adverse effects, Treatment Outcome, *Hip, Fractures/complications/surgery, *Stroke/etiology, Elderly, Intertrochanteric fracture, Postoperative delirium, Prediction, Reduction and internal fixation, Scoring system |
| A single preoperative low-dose dexamethasone may reduce the incidence and severity of postoperative delirium in the geriatric intertrochanteric fracture patients with internal fixation surgery: an exploratory analysis of a randomized, placebo-controlled t | Huang, J. W. Yang, Y. F. Gao, X. S. Xu, Z. H. | J Orthop Surg Res | 2023 |
Humans, Aged, *Emergence Delirium/drug therapy, Postoperative, Complications/epidemiology/etiology/prevention & control, Prospective Studies |
| Incidence of postoperative delirium in older adults undergoing surgical procedures: A systematic literature review and meta-analysis | Igwe, E. O. Nealon, J. O'Shaughnessy, P. Bowden, A. Chang, H. R. Ho, M. H. Montayre, J. Montgomery, A. Rolls, K. Chou, K. R. Chen, K. H. Traynor, V. Smerdely, P. | Worldviews Evid Based Nurs | 2023 |
Humans, Aged, *Emergence Delirium/complications, *Delirium/epidemiology/etiology/diagnosis, Postoperative, Complications/epidemiology/etiology, Incidence, Risk Factors, meta-analysis |
| Music to prevent deliriUm during neuroSurgerY (MUSYC): a single-centre, prospective randomised controlled trial | Kappen, P. R. Mos, M. I. Jeekel, J. Dirven, C. M. F. Kushner, S. A. Osse, R. J. Coesmans, M. Poley, M. J. van Schie, M. S. van der Holt, B. Klimek, M. Vincent, Ajpe | BMJ Open | 2023 |
Adult, Humans, *Music, *Neurosurgery, Prospective Studies, *Delirium/etiology/prevention & control/diagnosis, Neurosurgical, Procedures/adverse effects, clinical trials, complementary medicine, delirium & cognitive disorders, neurosurgery, preventive medicine |
| Intraoperative suggestions to prevent postoperative delirium in patients undergoing transaortic valvular replacement: a randomized placebo-controlled trial | Kaufmann, C. Zech, N. Brandt, F. Hilker, M. Debl, K. Creutzenberg, M. Zeman, F. Graf, B. M. Sinner, B. | Aging Clin Exp Res | 2023 |
Intraoperative suggestions, Postoperative delirium, Transcatheter aortic valve replacement |
| Association of cervical atherosclerosis on Doppler ultrasonography and postoperative delirium in patients undergoing spinal surgery: a single-center, retrospective, observational study | Kumagai, G. Wada, K. Asari, T. Nitobe, Y. Kinoshita, H. Kushikata, T. Hirota, K. Ishibashi, Y. | Eur Spine J | 2023 |
Cervical atherosclerosis, Older age, Postoperative delirium, Spinal surgery, Ultrasonography |
| Educational intervention for family caregivers of older adults with delirium: An integrative review | Lee, J. Yeom, I. Yoo, S. Hong, S. | J Clin Nurs | 2023 |
education, family, older patients, review |
| The presence of preoperative neurodegeneration biofluid markers in patients with postoperative delirium | Leung, J. M. Rojas, J. C. Tang, C. Chan, B. Lario-Lago, A. Boxer, A. L. Do, Q. Kramer, J. H. Du, Z. Du, P. Sands, L. P. | Anesthesiology | 2023 |
postoperative delirium, surgical, neurodegeneration, confusion assessment method, biomarkers |
| Visual Dysfunction is a Risk Factor of Post-operation Delirium in Parkinson's Disease | Li, C. Lian, C. Wu, Q. Q. Hou, Y. Zhao, W. B. Wang, X. Zhang, C. | World Neurosurg | 2023 |
Dbs, Pod, Parkinson ’s disease, Visual impairment |
| Relationship between in-hospital angiotensin converting enzyme inhibitors and Angiotensin receptor blockers administration and delirium in the cardiac ICU | Mulkey, M. A. Hauser, P. H. P. Aucoin, J. | Hosp Pract (1995) | 2023 |
ACE inhibitor, Angiotensin receptor blocker, Antihypertensives, cardiac intensive care unit, delirium |
| Predictors of cognitive impairment in patients undergoing ileostomy for colorectal cancer: a retrospective analysis | Xu, J. Yang, Y. Hu, D. | PeerJ | 2023 |
Humans, Retrospective Studies, Ileostomy, Quality of Life, *Cognitive, Dysfunction/diagnosis, *Postoperative Cognitive Complications, *Delirium |
| The effect of music therapy on delirium in patients receiving mechanical ventilatory support in the Intensive Care Unit: A protocol for systematic review and meta-analysis | Zhou, C. Ma, H. Qi, X. Xu, C. Liang, Z. | Medicine (Baltimore) | 2023 |
Humans, *Delirium/drug therapy, Intensive Care Units, *Meta-Analysis as Topic, *Music Therapy, *Systematic Reviews as Topic/methods |
| Incidence of and risk factors for post-intensive care syndrome among Chinese respiratory intensive care unit patients: A cross-sectional, prospective study | Zhou, M. Zhang, J. Xu, Z. Gu, H. Chen, Z. Ding, Y. | Aust Crit Care | 2023 |
Humans, Prospective Studies, Incidence, *Quality of Life, Cross-Sectional Studies, *Activities of Daily Living, East Asian People, Intensive Care Units, Risk Factors, Effect factors, Patients, Post–intensive care syndrome, Respiratory intensive care unit |
| The Impact of an Educational Programme on Jordanian Intensive Care Nurses' Knowledge, Attitudes, and Practice Regarding Delirium and their Levels of Self-Efficacy: A Quasi-Experimental Design | Alhalaiqa, F. Masa'Deh, R. Al Omari, O. Shawashreh, A. Khalifeh, A. H. Gray, R. | Iran J Nurs Midwifery Res | 2023 |
Attitude, delirium, education, intensive care units, knowledge, self efficacy |
| Nonpharmacological interventions for agitation in the adult intensive care unit: A systematic review | Adams, A. M. N. Chamberlain, D. Grønkjær, M. Brun Thorup, C. Conroy, T. | Aust Crit Care | 2023 |
Adult, Humans, Intensive Care Units, Psychomotor Agitation/therapy, Critical care, Delirium, Intensive care unit, Nonpharmacological interventions, Nursing, Psychomotor agitation, Systematic review |
| Postoperative Outcomes in Elderly Patients Undergoing Cardiac Surgery With Preoperative Cognitive Impairment: A Systematic Review and Meta-Analysis | Au, E. Thangathurai, G. Saripella, A. Yan, E. Englesakis, M. Nagappa, M. Chung, F. | Anesth Analg | 2023 |
Human, Aged, Delirium/etiology/complications, Cognitive, Dysfunction/complications, Postoperative Complications/diagnosis/etiology, Cardiac Surgical Procedures/adverse effect, Intensive Care Units |
| The prediction of postoperative delirium with the preoperative bispectral index in older aged patients: a cohort study | Bao, L. Liu, T. Zhang, Z. Pan, Q. Wang, L. Fan, G. Li, Z. Yin, Y. | Aging Clin Exp Res | 2023 |
Bis, Elderly patients, Monitoring, Postoperative delirium, Prediction, Preoperative predictive score |
| Insulin resistance, age and depression's impact on cognition in middle-aged adults from the PREVENT cohort | Bauermeister, S. D. Ben Yehuda, M. Reid, G. Howgego, G. Ritchie, K. Watermeyer, T. Gregory, S. Terrera, G. M. Koychev, I. | BMJ Ment Health | 2023 |
Middle Aged, Humans, Adult, Aged, Diabetes Mellitus, Type 2/epidemiology, Insulin Resistance, Depression/epidemiology, Cohort Studies, Cross-Sectional Studies, Cognition, Alzheimer Disease/psychology, delirium & cognitive disorders, depression & mood disorders, psychiatry |
| Key elements of an evidence-based clinical psychology service within adult critical care | Beadman, M. Carraretto, M. | J Intensive Care Soc | 2023 |
Psychology, critical care, delirium, follow-up clinics, post-intensive care syndrome |
| Neurofilament light chains to assess sepsis-associated encephalopathy: Are we on the track toward clinical implementation? | Bircak-Kuchtova, B. Chung, H. Y. Wickel, J. Ehler, J. Geis, C. | Crit Care | 2023 |
Humans, Sepsis-Associated Encephalopathy/complications/diagnosis, Intermediate Filaments, Sepsis/complications/diagnosis, Biomarkers, Brain Diseases, Biomarker, Brain dysfunction, Delirium, Encephalopathy, Neurofilament light chain, Sae, Sepsis |
| Veterans' experiences of moral injury, treatment and recommendations for future support | Bonson, A. Murphy, D. Aldridge, V. Greenberg, N. Williamson, V. | BMJ Mil Health | 2023 |
anxiety disorders, delirium & cognitive disorders, depression & mood disorders, public health |
| General Anesthesia Versus Regional Anesthesia in the Elderly Patients Undergoing Hip Fracture Surgeries: A Systematic Review and Meta-Analysis of Randomized Clinical Trials | Cao, M. M. Zhang, Y. W. Sheng, R. W. Gao, W. Kang, Q. R. Gao, Y. C. Qiu, X. D. Rui, Y. F. | World J Surg | 2023 |
Humans, Aged, Emergence Delirium, Blood Loss, Surgical/prevention & control, Postoperative Complications/epidemiology/etiology, Randomized Controlled Trials as Topic, Anesthesia, General, Anesthesia, Conduction, Hip Fractures/surgery |
| Delirium in ventilated patients receiving fentanyl and morphine for Analgosedation: Findings from the ANALGESIC trial | Casamento, A. Neto, A. S. Lawrence, M. Chudleigh, L. Browne, E. Taplin, C. Eastwood, G. M. Bellomo, R. | J Crit Care | 2023 |
Analgosedation, Delirium, Mechanical ventilation, Opioids |
| Postoperative delirium after intracranial neurosurgery: A prospective cohort study from a developing nation | Chakrabarti, D. Bharadwaj, S. Akash, V. S. Wadhwa, A. Konar, S. Kamath, S. Gopalakrishna, K. N. | Acta Neurochir (Wien) | 2023 |
Humans, Emergence Delirium/complications, Delirium/epidemiology/etiology |
| Incidence of preoperative instrumental activities of daily living (IADL) dependence and adverse outcomes in older surgical patients: A systematic review and meta-analysis | Chen, A. An, E. Yan, E. He, D. Saripella, A. Butris, N. Tsang, J. Englesakis, M. Wong, J. Alibhai, S. Chung, F. | J Clin Anesth | 2023 |
Delirium, systematic review and meta-analysis, Functional dependence,, Instrumental activities of daily living (IADL), Older patients, Preoperative assessment |
| Heterogeneity in the definition of delirium in ICUs and association with the intervention effect in randomized controlled trials: a meta-epidemiological study | Collet, L. Lanore, A. Alaterre, C. Constantin, J. M. Martin, G. L. Caille, A. James, A. Dechartres, A. | Crit Care | 2023 |
Humans, Delirium/diagnosis/epidemiology/therapy, Epidemiologic Studies, Intensive Care Units, Randomized Controlled Trials as Topic, Meta-Analysis as Topic, Definition, Delirium, Heterogeneity, Intensive care, Meta-analysis, Meta-epidemiology |
| A prospective multicentre observational study to quantify nocturnal light exposure in intensive care | Craig, T. Mathieu, S. Morden, C. Patel, M. Matthews, L. | J Intensive Care Soc | 2023 |
Light, circadian rhythm, delirium, environment, light pollution |
| Recognizing and Reducing Delirium in the Intensive Care Unit | Dechant, T. Smith, L. Chavez, J. | Crit Care Nurs Q | 2023 |
Humans, Disease Progression, Intensive Care Units |