What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Platelet Bioenergetics and Associations With Delirium and Coma in Patients With Sepsis: A Prospective Cohort Study
- Authors
- Onyemekwu, C. A. Prendergast, N. T. Potter, K. M. Toney, N. A. Nouraie, M. S. Shiva, S. Girard, T. D.
- Year
- 2024
- Journal
- CHEST Crit Care
- Abstract
BACKGROUND: Acute brain dysfunction during sepsis, which manifests as delirium or coma, is common and is associated with multiple adverse outcomes, including longer periods of mechanical ventilation, prolonged hospital stays, and increased mortality. Delirium and coma during sepsis may be manifestations of alteration in systemic metabolism. Because access to brain mitochondria is a limiting factor, measurement of peripheral platelet bioenergetics offers a potential opportunity to understand metabolic changes associated with acute brain dysfunction during sepsis. RESEARCH QUESTION: Are altered platelet mitochondrial bioenergetics associated with acute brain dysfunction during sepsis? STUDY DESIGN AND METHODS: We assessed participants with critical illness in the ICU for the presence of delirium or coma via validated assessment measures. Blood samples were collected and processed to isolate and measure platelet mitochondrial oxygen consumption. We used Seahorse extracellular flux to measure directly baseline, proton leak, maximal oxygen consumption rate, and extracellular acidification rate. We calculated adenosine triphosphate-linked, spare respiratory capacity, and nonmitochondrial oxygen consumption rate from the measured values. RESULTS: Maximum oxygen consumption was highest in patients with coma, as was spare respiratory capacity and extracellular acidification rate in unadjusted analysis. After adjusting for age, sedation, modified Sequential Organ Failure Assessment score without the neurologic component, and preexisting cognitive function, increased spare respiratory capacity remained associated with coma. Delirium was not associated with any platelet mitochondrial bioenergetics. INTERPRETATION: In this single-center exploratory prospective cohort study, we found that increased platelet mitochondrial spare respiratory capacity was associated with coma in patients with sepsis. Future studies powered to determine any relationship between delirium and mitochondrial respiration bioenergetics are needed.
- PMID
PMID: 38938510
PMCID: PMC11210717
NIHMSID: NIHMS2002604
- Keywords
acute brain dysfunction
bioenergetics
coma
delirium
platelet mitochondria
sepsis
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Risk factors of delirium after Sun's procedure for acute type A aortic dissection and its influence on patients' prognosis | Zhu, Q. Y. Xue, J. R. Bai, T. Qiao, H. Y. Yang, B. Zhang, K. F. Li, S. M. Zhang, W. Zhang, Z. Chang, C. M. Liu, Y. M. | Zhonghua Yi Xue Za Zhi | 2025 |
Humans Male Female Risk Factors Middle Aged *Aortic Dissection/surgery Prognosis *Delirium/etiology Retrospective Studies *Postoperative Complications *Aortic Aneurysm/surgery Logistic Models Aged |
| The Impact of a Pharmacist-Driven Multicomponent Sleep-Promoting Protocol on Delirium in Critically Ill Patients | Zelenkov, D. Hollins, R. Mahoney, E. J. Faugno, A. J. Poyant, J. | J Pharm Pract | 2024 |
Humans *Delirium/epidemiology/prevention & control/diagnosis *Pharmacists *Critical Illness/therapy/epidemiology Female Male Middle Aged Intensive Care Units Prospective Studies Aged Respiration, Artificial/methods/adverse effects Length of Stay *Sleep/drug effects/physiology Clinical Protocols Professional Role *Sleep Deprivation *Sleep Aids, Pharmaceutical/administration & dosage/therapeutic use delirium intensive care pharmacist sleep protocol sleep quality |
| Frailty and the Risk of Delirium: A Mendelian Randomization Study | Yu, M. Li, B. | Crit Care Nurs Q | 2025 |
Humans *Delirium/genetics/epidemiology Mendelian Randomization Analysis *Frailty/genetics/complications Aged Genome-Wide Association Study Risk Factors Male Female Intensive Care Units Mendelian randomization delirium frailty genetic variant |
| A nomogram for predicting delirium in the ICU among older patients with chronic obstructive pulmonary disease | Yu, C. Li, T. Xu, M. Xu, H. Lei, X. Xu, Z. Hu, J. Zheng, X. Chen, C. Zhao, H. | BMC Geriatr | 2025 |
Humans *Nomograms Aged Male Female *Delirium/diagnosis/epidemiology/etiology/psychology *Pulmonary Disease, Chronic Obstructive/psychology/diagnosis/therapy/epidemiology/complications *Intensive Care Units/trends Aged, 80 and over Predictive Value of Tests Risk Factors Chronic obstructive pulmonary disease ICU delirium Intensive care unit MIMIC-IV database Nomogram |
| Delirium in Critically Ill Geriatric Surgical Patients: A Systematic Review of Screening, Risk Factors, Diagnosis, and Management | Yates, Z. Lee, P. Espat, N. N. Zagales, R. Hernandez, N. Amin, Q. Ford, A. Tweedie, C. Elkbuli, A. | J Trauma Nurs | 2025 |
Critically ill geriatric surgical patients Delirium Diagnostic tools Early screening tools Management Prevention strategies Risk factors |
| Predictive ability of Mini-Cog for postoperative delirium: A systematic review and meta-analysis | Yajima, S. Hirose, K. Masuda, H. | Geriatr Gerontol Int | 2025 |
cognitive function delirium mini‐cog postoperative delirium screening |
| Effect of transcranial direct current stimulation on postoperative delirium in elderly patients undergoing hip fracture surgery: study protocol for a randomized controlled trial | Xue, L. C. Ji, H. J. Fan, S. S. Niu, Q. Zhang, J. Y. Fang, A. L. Wang, P. Z. Tian, S. Y. Zheng, H. | Front Med (Lausanne) | 2025 |
clinical protocols hip fracture post-operative delirium quality of recovery transcranial direct current stimulation |
| Comprehensive Machine Learning-Based Prediction Model for Delirium Risk in Older Patients with Dementia: Risk Factors Identification | Xiao, Q. Zhou, S. Tang, B. Zhu, Y. | Clin Interv Aging | 2025 |
Humans *Delirium/diagnosis/etiology/epidemiology Aged *Machine Learning Male Female *Dementia/complications/epidemiology Risk Factors Aged, 80 and over Prospective Studies Risk Assessment/methods Hospitalization Algorithms ROC Curve delirium dementia machine learning older prediction |
| Transcutaneous auricular vagus nerve stimulation prevents postoperative delirium in elderly patients (VNSTAR): protocol for a multicentre, randomised controlled trial | Wu, Y. Hou, X. Wang, T. Wang, X. Zhang, K. Liang, F. Jian, M. Wang, B. Liu, H. Wang, A. Han, R. | BMJ Open | 2025 |
Humans Aged Double-Blind Method *Vagus Nerve Stimulation/methods Multicenter Studies as Topic Randomized Controlled Trials as Topic *Postoperative Complications/prevention & control *Transcutaneous Electric Nerve Stimulation/methods *Delirium/prevention & control China Male Female Anaesthetics Cognition Delirium |
| Risk Prediction Models of Subsyndromal Delirium in Critically Ill Patients: A Systematic Review and Meta-Analysis | Wu, F. Wang, T. Xing, Y. Cai, W. Zhang, R. | Nurs Crit Care | 2025 |
Humans *Delirium/diagnosis/epidemiology *Critical Illness Risk Assessment/methods Intensive Care Units Apache Risk Factors intensive care unit meta‐analysis risk prediction model subsyndromal delirium systematic review |
| A retrospective study on the relationship between delirium and long-term cognitive function in elderly women following cervical cancer surgery | Wang, Y. Yin, Y. Wei, Z. Zhou, N. Yao, X. | Medicine (Baltimore) | 2025 |
Humans Female Retrospective Studies Aged *Delirium/epidemiology/etiology *Uterine Cervical Neoplasms/surgery/psychology Risk Factors *Postoperative Complications/epidemiology/etiology/psychology Middle Aged *Cognitive Dysfunction/etiology/epidemiology Cognition Aged, 80 and over Mental Status and Dementia Tests Mmse cervical cancer surgery elderly women long-term cognitive function postoperative delirium psychiatric history |
| Association of remimazolam with delirium and cognitive function in elderly patients undergoing general anesthesia or procedural sedation: a meta-analysis of randomized controlled trials | Wang, Y. Gou, Z. H. Wang, G. M. Ye, L. H. Chen, L. Wang, Q. | Front Med (Lausanne) | 2025 |
cognitive function delirium elderly postoperative remimazolam |
| Glucose-to-Albumin Ratio as a New Predictive Indicator for Postoperative Delirium in Geriatric Hip Fracture Patients | Wang, W. Yao, W. Tang, W. Li, Y. Liu, Y. Lv, Q. Ding, W. | J Arthroplasty | 2025 |
Humans *Hip Fractures/surgery/blood Female Male Aged Aged, 80 and over *Delirium/blood/etiology/diagnosis Biomarkers/blood *Blood Glucose/analysis *Postoperative Complications/blood/etiology/diagnosis Predictive Value of Tests *Serum Albumin/analysis Retrospective Studies Propensity Score *Arthroplasty, Replacement, Hip/adverse effects ROC Curve Gar glucose-to-albumin ratio hip fracture postoperative delirium predictive indicator |
| Association of cardiometabolic multimorbidity with postoperative delirium and three-year mortality in patients undergoing knee/hip arthroplasty: a prospective cohort study | Wang, K. Zhang, A. Kong, W. Wang, Y. Liang, Y. Lin, Y. Li, C. Wang, J. Gong, H. Bi, Y. Wang, B. Lin, X. | Int J Surg | 2025 |
anesthesiology cardiometabolic multimorbidity cerebrospinal fluid cohort study delirium neuropsychological tests postoperative delirium |
| Geriatric Nutritional Risk Index as a Predictor of Delirium and Pressure Injuries in Critically Ill Older Patients With Ischaemic Stroke: An Observational Cohort Study | Wang, D. Liu, A. Liang, X. Fan, H. Han, B. He, L. Hong, Y. Li, Q. | Nurs Crit Care | 2025 |
Humans Female *Delirium/epidemiology/etiology Male Aged *Pressure Ulcer/epidemiology/etiology Critical Illness *Geriatric Assessment/methods Cohort Studies *Malnutrition/complications *Ischemic Stroke/complications Risk Factors *Nutrition Assessment Risk Assessment Aged, 80 and over Prevalence Intensive Care Units delirium geriatric nutritional risk index ischaemic stroke malnutrition older adults pressure injury |
| Geriatric syndromes associated with long-term mortality in adults aged 90 years and older | Veizi, B. G. Y. Naharcı, M. I. | Geriatr Nurs | 2025 |
Dementia Geriatric syndrome Malnutrition Mortality Nonagenarians |
| 10 key issues for prevention, monitoring and non-pharmacological treatment of delirium in critically ill patients | Vallés-Fructuoso, O. Rodríguez-Mondéjar, J. J. Alonso-Crespo, D. Robleda-Font, G. López-López, C. Gil-Castillejos, D. Acevedo-Nuevo, M. | Enferm Intensiva (Engl Ed) | 2025 |
Delirium, Intensive care units, Non-pharmacological interventions, Registered nurse |
| Brain Pro-TCT: a prospective, quasi-experimental study on early delirium detection with Delirium Observation Screening Scale vs. single-channel EEG after cardiac surgery in patients aged over 70 years | Ten Broeke, M. Henckens, W. P. R. Weierink, A. Speekenbrink, R. G. H. van der Palen, J. Halfwerk, F. R. | Eur J Cardiovasc Nurs | 2025 |
Humans Prospective Studies Male Female Aged *Electroencephalography/methods *Delirium/diagnosis/etiology *Cardiac Surgical Procedures/adverse effects *Postoperative Complications/diagnosis Early Diagnosis Aged, 80 and over Length of Stay/statistics & numerical data Mass Screening/methods Delirium Delta rhythm Elderly Electroencephalography Thoracic surgery |
| Systematic Mendelian randomization of the human plasma proteome to identify therapeutic targets linking aging and frailty to perioperative delirium | Tang, J. Qian, Z. Zhu, Z. Qin, H. Cai, G. Wang, Y. Wei, Z. Rao, X. Yang, L. Zou, X. Ren, Y. | J Affect Disord | 2025 |
Aging Delirium Mendelian randomization Proteome |
| Directed acyclic graphs to minimise bias and optimise causal inference in SNAP-3: an observational cohort study of frailty, multimorbidity, and delirium in older surgical patients | Swarbrick, C. J. Blake, H. A. Martin, P. Partridge, J. S. L. Moppett, I. K. | Br J Anaesth | 2025 |
directed acyclic graphs epidemiology frailty syndrome geriatric medicine multimorbidity perioperative care surgery |
| Long-term delirium and survival outcomes in patients treated with GLP-1 receptor agonists versus metformin in type 2 diabetes: A population-based cohort study | Sun, M. Wang, X. Lu, Z. Yang, Y. Lv, S. Miao, M. Chen, W. M. Wu, S. Y. Zhang, J. | Diabetes Obes Metab | 2025 |
GLP‐1 receptor agonists delirium metformin mortality type 2 diabetes mellitus |
| Metformin vs. second-line therapy for delirium prevention in type 2 diabetes: A multinational study | Sun, M. Wang, X. Lu, Z. Yang, Y. Lv, S. Miao, M. Chen, W. M. Wu, S. Y. Zhang, J. | Diabetes Res Clin Pract | 2025 |
Delirium Dementia Dipeptidyl peptidase-4 inhibitors Epidemiology Metformin Neurocognitive decline Type 2 diabetes |
| SGLT2i Versus Metformin for Delirium Prevention in Type 2 Diabetes: A Real-World, Head- to-Head Comparative Study | Sun, M. Wang, X. Lu, Z. Yang, Y. Lv, S. Miao, M. Chen, W. M. Wu, S. Y. Zhang, J. | Diabetes Care | 2025 |
SGLT2is, delirium, type 2 diabetes, metformin, cognitive outcomes |
| Analyzing Key Predictors of Postoperative Delirium Following Coronary Artery Bypass Grafting and Aortic Valve Replacement: A Machine Learning Perspective | Stošić, M. Perić, V. Milić, D. Lazarević, M. Živadinović, J. Stojiljković, V. Kamenov, A. Nikolić, A. Golubović, M. | Medicina (Kaunas) | 2025 |
Humans Male *Machine Learning Female Aged *Coronary Artery Bypass/adverse effects/methods Middle Aged *Delirium/etiology/diagnosis *Postoperative Complications/etiology Risk Factors *Heart Valve Prosthesis Implantation/adverse effects Logistic Models Aortic Valve/surgery Respiration, Artificial/adverse effects ROC Curve aortic valve replacement coronary artery bypass machine learning postoperative delirium predictive modeling |
| Long-term and preoperative benzodiazepine use in older adults and risk for postoperative delirium: An additional analysis of the multicentre Biomarker Development for Postoperative Cognitive Impairment in the Elderly Study | Starks, S. C. E. Pohrt, A. Halzl-Yürek, F. Heinrich, M. Müller, A. Spies, C. D. Winterer, G. Zacharias, N. | Eur J Anaesthesiol | 2025 |
Postoperative delirium, benzodiazepines, surgery, biomarkers |
| Effect of Cerebrolysin on Cognitive Function and Delirium in Coronary Artery Bypass Graft Patients | Stadnik, A. Jezierska, M. Płotek, W. Siwicka, D. Mlak, R. Dąbrowski, W. | Med Sci Monit | 2025 |
Humans *Coronary Artery Bypass/adverse effects/methods Male Female *Cognition/drug effects *Delirium/drug therapy/etiology *Amino Acids/pharmacology/therapeutic use Middle Aged Aged Postoperative Complications |
| Incidence and delirium risk factors in burn patients: A prospective cohort study | Silva, M. P. Vala, J. Sousa, J. Teixeira, J. F. Henriques, H. R. | Burns | 2025 |
Burns Comorbidity Delirium Incidence Risk factors |
| Delirium risk associated with esketamine, sevoflurane, propofol, and dexmedetomidine: A real-world study based on the FDA adverse event reporting system | Shuai, Y. Liu, Y. Yang, X. Wan, Q. Zhao, J. Wang, X. | Eur J Pharmacol | 2025 |
Delirium Dexmedetomidine Esketamine Faers Propofol Real-world Sedative drugs Sevoflurane |
| Knowledge, Attitude, and Practice Levels of Nurses in Primary Hospitals Regarding Elderly Subsyndromal Delirium: Assessment and Development of a Network-Based Tiered Training Program | Shu, X. Wang, F. He, J. Huang, F. | Br J Hosp Med (Lond) | 2025 |
Humans *Delirium/nursing/diagnosis Female Male Surveys and Questionnaires *Health Knowledge, Attitudes, Practice *Nursing Staff, Hospital/education/psychology Aged Adult China Delphi Technique Middle Aged *Clinical Competence Pilot Projects Reproducibility of Results Attitude of Health Personnel attitude elderly knowledge network-based nurses practice primary hospital subsyndromal delirium training |
| Identifying the Influence of Lung-Related Injuries and Other Factors on Delirium in Traumatic Brain Injury Patients: A National Analysis | Shin, J. Nahmias, J. Chen, P. Chen, J. Lekawa, M. Nguyen, L. Grigorian, A. | J Head Trauma Rehabil | 2025 |
delirium lung injury traumatic brain injury traumatic lung injury |
| Incidence and Risk Factors of Postoperative Delirium in Elderly Patients Following Hip Fracture Surgery: A Nationwide Retrospective Cohort Study in Taiwan | Shih, C. A. Yang, D. C. Wang, W. M. Wu, Y. L. Yang, Y. C. Ku, H. C. | Int J Geriatr Psychiatry | 2025 |
Humans Taiwan/epidemiology *Hip Fractures/surgery Female Male Retrospective Studies Risk Factors Aged Incidence Aged, 80 and over *Delirium/epidemiology/etiology *Postoperative Complications/epidemiology Proportional Hazards Models Sex Factors cohort study delirium elderly hip fracture surgery |
| The Impact of Anesthetic Management Under Bispectral Index Monitoring on the Early Recovery Quality of Elderly Patients Undergoing Laparoscopic Surgery: A Blinded Randomized Controlled Trial | Shi, M. Long, Y. Zhou, Z. Huang, L. Wu, D. Zhang, X. | Clin Interv Aging | 2025 |
Aged Aged, 80 and over Female Humans Male Middle Aged *Anesthesia Recovery Period *Anesthesia, General/methods Anesthetics, Intravenous/administration & dosage *Consciousness Monitors Emergence Delirium/epidemiology *Laparoscopy/methods Length of Stay Propofol/administration & dosage Bis bispectral index cognitive function elderly patients quality of postoperative recovery sleep quality |
| Dexmedetomidine increases the risk of delirium in critically ill patients: A propensity score analysis | Shi, H. J. Li, H. W. Lu, Y. F. Zhang, X. Y. Hu, A. M. Huo, J. | Medicine (Baltimore) | 2025 |
Humans *Dexmedetomidine/adverse effects/administration & dosage *Delirium/chemically induced/epidemiology Propensity Score Male Female *Critical Illness *Hypnotics and Sedatives/adverse effects/administration & dosage Middle Aged Aged Intensive Care Units/statistics & numerical data Length of Stay/statistics & numerical data Risk Factors Retrospective Studies critically ill patients delirium dexmedetomidine propensity score analysis |
| Incidence of postoperative delirium among patients who underwent head & neck surgery | Senirli, R. T. Gediz, D. Yüksel, Y. Yildiz, M. Ensari, N. Yilmaz, N. D. S. GüR, ÖE | Oral Maxillofac Surg | 2025 |
Humans Male Female Incidence *Delirium/epidemiology/etiology Prospective Studies Middle Aged Risk Factors Aged *Postoperative Complications/epidemiology Adult *Head and Neck Neoplasms/surgery Aged, 80 and over Mental Status and Dementia Tests Operative Time Cognitive impairment Delirium Minimental test Surgery duration |
| Determining the ground truth for the prediction of delirium in adult patients in acute care: a scoping review | Schöler, L. M. Graf, L. Airola, A. Ritzi, A. Simon, M. Peltonen, L. M. | JAMIA Open | 2025 |
delirium electronic health records ground truth machine learning prediction models |
| Early identification and delirium recognition in acute care: A quality improvement initiative | Sanga, S. K. Ansryan, L. Z. | Geriatr Nurs | 2025 |
Confusion assessment method (CAM) Delirium Early identification Geriatric clinical nurse specialist (GCNS) Geriatric nurse champions (GNCS) quality improvement (QI) |
| Impact of Living Arrangements on Delirium in Older ED Patients | Russo, A. Salini, S. Carbone, L. Piccioni, A. Fontanella, F. P. Ambrosio, F. Massaro, C. Della Polla, D. De Matteis, G. Franceschi, F. Landi, F. Covino, M. | J Clin Med | 2025 |
comprehensive geriatric assessment delirium emergency department frailty living arrangement |
| Associations of Intraoperative Hypotension, and Perioperative Blood Pressure with Delirium after Noncardiac Surgery: A Retrospective Cohort Analysis | Rössler, J. Kopac, O. Marquez Roa, L. Bajracharya, G. R. Wang, L. Ruetzler, K. Turan, A. | Anesthesiology | 2025 |
Delirium, postoperative delirium, non-cardiac surgery, hypotension, blood pressure, mean arterial pressure |
| The 3-Minute Diagnostic Confusion Assessment Method severity score correlates with the Delirium Rating Scale-Revised-98 and with biomarkers of delirium | Rivera, C. Kunkel, D. Her, M. Qureshi, S. Pearce, R. A. Sanders, R. D. Lennertz, R. | BJA Open | 2025 |
3d-cam Cam Drs biomarker delirium postoperative severity surgery |
| Bedside-teaching on dementia and delirium: Development, implementation, and evaluation in an acute care hospital | Radler, A. Ewers, A. | Pflege | 2025 |
Humans *Delirium/nursing Curriculum *Dementia/nursing *Inservice Training Pilot Projects Clinical Competence Aged Male Female Switzerland Delir Dementia Demenz Evaluationsforschung Schulung delirium evaluation study teaching |
| A Comparison of Monotherapy and Combination Therapy With Antipsychotic Medications for Intensive Care Unit Delirium: A Retrospective Cohort Study | Nguyen, A. Chang, J. Allison-Aipa, T. Albini, P. | Ann Pharmacother | 2025 |
Cam-icu antipsychotic agents critical care delirium intensive care unit |
| Improving Recovery and Outcomes Every Day After the ICU (IMPROVE): A Randomized Controlled Trial | Khan, S. H. Perkins, A. J. Unverzagt, F. W. Wang, S. Moser, L. R. Moiz, S. Jawaid, S. Corlett, D. Clark, D. O. Boustani, M. A. Gao, S. Khan, B. A. | Crit Care Med | 2025 |
cognitive training critical care delirium physical exercise post-intensive care syndrome |
| Nursing Support for Nonpharmacological Interventions to Prevent Delirium in Patients with Cancer: A Scoping Review | Kanno, Y. Nakano, K. Kajiwara, K. Kobayashi, M. Morikawa, M. Matsuda, Y. Shimizu, Y. Niino, M. Suzuki, M. Shimazu, T. Kako, J. | J Palliat Med | 2025 |
cancer delirium prevention nonpharmacological intervention nursing support scoping review |
| Delirium: long-term sequelae and aftercare with special consideration to posttraumatic stress disorder | Med Klin Intensivmed Notfmed | Med Klin Intensivmed Notfmed | 2025 |
Humans *Stress Disorders, Post-Traumatic/psychology/diagnosis/therapy/mortality *Delirium/diagnosis/therapy/psychology/mortality/epidemiology *Aftercare Risk Factors Intensive Care Units Critical Care/psychology Cross-Sectional Studies Critical Illness Critically ill patients ICU delirium Post-intensive care syndrome Posttraumatic stress disorder Prevention and management |
| Neurological Orientation and Verbal Assessment of Delirium-Hospital Clinical Decision Support Tool | Hendrie, K. Rangan, P. Agarwal, S. K. Pagali, S. Khan, B. Kidwai, S. Agarwal, N. | J Med Syst | 2025 |
Adult Aged Aged, 80 and over Female Humans Male Middle Aged *Decision Support Systems, Clinical *Delirium/diagnosis *Electronic Health Records Hospitalization *Nursing Assessment/methods Retrospective Studies Sensitivity and Specificity Cross-Sectional Studies Clinical decision support Delirium Hospital tool |
| Cost-effectiveness of adopting a postoperative delirium risk prediction tool with nonpharmacological delirium prevention interventions for surgical patients | Graves, N. Böttger, S. Zozmann, M. Franziska, M. Stocker, R. | Age Ageing | 2025 |
Humans Cost-Benefit Analysis Aged *Delirium/prevention & control/economics/etiology/diagnosis Quality-Adjusted Life Years Risk Assessment Male Decision Trees Female Risk Factors Middle Aged Switzerland *Decision Support Techniques Models, Economic Aged, 80 and over Predictive Value of Tests *Postoperative Complications/prevention & control/economics Prospective Studies *Surgical Procedures, Operative/adverse effects/economics Hospital Costs adoption cost-effective costs older people risks screening |
| Delirium Identification from Nursing Reports Using Large Language Models | Graf, L. Ritzi, A. Schoeler, L. M. | Stud Health Technol Inform | 2025 |
*Delirium/diagnosis/nursing/classification *Natural Language Processing Humans *Nursing Records/classification *Nursing Diagnosis/methods *Electronic Health Records Germany *Data Mining/methods Reproducibility of Results *Diagnosis, Computer-Assisted/methods Sensitivity and Specificity Large Language Models Delirium Electronic Health Records |
| Integrated transcriptomic and immune profiling reveals crucial molecular pathways and hub genes associated with postoperative delirium in elderly patients | Gou, Z. H. Su, N. Li, X. C. Ren, D. P. Ren, S. S. Wang, L. Wang, Y. | Front Med (Lausanne) | 2025 |
Ppi Wgcna cell death elderly immune microenvironment postoperative delirium |
| Participatory Design of an AI-Based CDSS for Delirium Prevention | Gleim, P. Ritzi, A. Mählmann, S. Heizmann, C. Ziegler, S. Kellmeyer, P. | Stud Health Technol Inform | 2025 |
*Delirium/prevention & control/diagnosis *Artificial Intelligence Humans *Decision Support Systems, Clinical/organization & administration Ai Cdss delirium healthcare professionals nursing participation |
| The Effect of Intraoperative Dexmedetomidine on Postoperative Delirium Sedation Agitation Score in cardiac surgery | Ghanbarpour, M. H. Dabbagh, A. Jahangirifard, A. Shafigh, N. Fani, M. Fani, K. | Anesth Pain Med | 2025 |
Cardiac Surgery Dexmedetomidine Postoperative Delirium |
| Associations of Intensive Care Unit Acquired Weakness and Postoperative Delirium in Surgical Intensive Care Unit: A Prospective Observation Study | Qiu, J. Meng, Y. Yang, Z. Ren, R. Chen, J. Huang, H. Feng, T. Ge, X. | Nurs Crit Care | 2025 |
Humans Male Prospective Studies Female Aged *Intensive Care Units/statistics & numerical data China/epidemiology *Delirium/epidemiology/etiology *Postoperative Complications/epidemiology Middle Aged *Muscle Weakness/etiology/epidemiology Risk Factors ICU acquired weakness Sicu hypoactive POD postoperative delirium |
| Mortality Risk Following Delirium in Older Inpatients: A Systematic Review and Meta-Analysis | Pérez-Ros, P. Plaza-Ortega, N. Martínez-Arnau, F. M. | Worldviews Evid Based Nurs | 2025 |
Humans *Delirium/mortality/complications Aged Aged, 80 and over Length of Stay/statistics & numerical data *Inpatients/statistics & numerical data/psychology Incidence Risk Factors *Mortality/trends delirium hospital length of stay mortality older people risk |
| Dual Orexin Receptor Antagonists for Delirium: A Scoping Review and Feasibility Trial of Daridorexant | Oldham, M. A. Lander, H. L. Choi, J. J. Gloff, M. S. Knight, P. A. Nadler, J. W. | J Acad Consult Liaison Psychiatry | 2025 |
daridorexant delirium dual orexin receptor antagonists heart surgery sleep-wake disturbance |
| The Impact of Delirium on Hospitalized Patients With COPD Exacerbation: Insights From the National In-Patient Sample | Ogbughalu, P. Odeyemi, Y. El Labban, M. | Respir Care | 2025 |
Copd delirium exacerbation in-patient mortality |
| Associations between Aβ40, Aβ42, and tau and postoperative delirium in older adults undergoing cardiac surgery | McKay, T. B. Smith, M. Mueller, A. Li, H. Patel, P. H. Freedman, I. G. Qu, J. Z. Akeju, O. | J Neurol | 2025 |
Humans *Amyloid beta-Peptides/blood Aged Male Female *Delirium/blood/etiology *Peptide Fragments/blood *Cardiac Surgical Procedures/adverse effects *tau Proteins/blood *Postoperative Complications/blood Middle Aged Aged, 80 and over Biomarkers/blood Alzheimer’s disease and related dementias Amyloid plaques Amyloid precursor protein Blood-based biomarkers Cognitive dysfunction Neurodegeneration |
| Impact of general anesthesia and spinal anesthesia on postal delirium and risk factors in elderly patients undergoing hip fracture surgery | Ma, L. Hao, J. Wang, S. Yang, K. Liang, W. Gu, F. | Am J Transl Res | 2025 |
Hip fracture postoperative delirium risk factor analysis spinal anesthesia |
| Delirium following emergency surgery in patients with gastrointestinal obstruction or perforation: A retrospective cohort study for 5 years | Lyu, W. Wang, Z. Yang, C. Wang, X. Feng, H. Jiao, Y. Liao, H. Wang, H. | J Gastrointest Surg | 2025 |
Acute abdomen Delirium Risk factors |
| The intersection of delirium and long-term cognition in older adults: the critical role of delirium prevention | Lu, Z. Wang, X. Wang, J. Zhao, L. Wu, Y. Sun, M. Zhang, J. | J Neurol | 2025 |
Humans *Delirium/prevention & control/complications/epidemiology Aged *Dementia/prevention & control *Cognitive Dysfunction/prevention & control Alzheimer’s disease Biomarker Delirium Dementia Prevention |
| Development and validation of a postoperative delirium risk prediction model for non-cardiac surgery in elderly patients | Lin, X. Tian, N. Wang, Y. Hua, S. Kong, J. Xu, S. Lin, Y. Li, C. Wang, B. Bi, Y. | Front Psychiatry | 2025 |
delirium elderly non-cardiac surgery prediction model risk factors |
| Association between combinations of preoperative comorbidities and postoperative delirium in older patients: a matched cohort study | Li, A. Song, Y. Shi, W. Mi, W. Lou, J. Liu, J. | BMC Anesthesiol | 2025 |
Humans Female Male Aged Retrospective Studies Comorbidity *Postoperative Complications/epidemiology Risk Factors Cohort Studies Aged, 80 and over *Delirium/epidemiology Propensity Score Hypertension/epidemiology Older patients Postoperative delirium Preoperative comorbidities Propensity-score matching |
| Multiprofessional perspectives on intersectoral collaboration for the prevention of postoperative delirium in older patients-A qualitative study | Krutter, S. Muzzana, C. Flamm, M. Iglseder, B. Piccoliori, G. Ruffini, I. Kutschar, P. Ausserhofer, D. | Z Gerontol Geriatr | 2025 |
Interprofessional collaboration Outpatient and inpatient settings Postoperative delirium Prevention Qualitative methods |
| The role of diabetes mellitus on delirium onset: a systematic review and meta-analysis | Komici, K. Fantini, C. Santulli, G. Bencivenga, L. Femminella, G. D. Guerra, G. Mone, P. Rengo, G. | Cardiovasc Diabetol | 2025 |
Humans *Delirium/epidemiology/diagnosis/prevention & control/psychology Incidence Risk Factors *Hypoglycemic Agents/therapeutic use/adverse effects/administration & dosage Risk Assessment *Diabetes Mellitus/epidemiology/drug therapy/diagnosis/psychology Female Male Aged Middle Aged Insulin/administration & dosage Metformin/therapeutic use/administration & dosage Treatment Outcome Delirium Diabetes mellitus Elderly Insulin Metformin |
| Outcomes associated with older patients who present or develop delirium in the emergency department: protocol for a systematic review and meta-analysis | King, S. Uleberg, O. Pedersen, S. A. Bjørnsen, L. P. | BMJ Open | 2025 |
Humans *Delirium Systematic Reviews as Topic *Emergency Service, Hospital Meta-Analysis as Topic Aged Research Design Length of Stay Quality of Life Patient Readmission/statistics & numerical data Patient Discharge Adverse events Delirium Emergency Departments Systematic Review |
| Whole-blood transcriptomic analysis reveals preoperative complement inhibitor deficiencies linked to postoperative delirium | Kelly Graves, O. Kang, J. Li, H. Erdin, S. Smith, M. Mueller, A. Simon, C. Wiredu, K. Bhave, V. De Esch, C. Lemanski, J. Talkowski, M. E. Rhee, J. Qu, J. McKay, T. B. Akeju, O. | Mol Psychiatry | 2025 |
postoperative delirium, perioperative care, ICU delirium, C4BPA, CD55 |
| A Randomized Clinical Trial of Dexmedetomidine on Delirium, Cognitive Dysfunction, and Sleep After Non-Ambulatory Orthopedic Surgery With Regional Anesthesia | Karageorgos, V. Darivianaki, P. Spartinou, A. Christofaki, M. Chatzimichali, A. Nyktari, V. Simos, P. Papaioannou, A. | Anesth Analg | 2025 |
postoperative delirium, emergence delirium, postoperative cognitive dysfunction, sleep disturbance, surgery |
| Development and internal verification of nomogram for forecasting delirium in the elderly admitted to intensive care units: an analysis of MIMIC-IV database | Jiang, L. Yu, D. Yang, G. Wu, X. Zhang, D. | Front Neurol | 2025 |
delirium elderly intensive care unit nomogram prediction model |
| A correlational study of plasma galectin-3 as a potential predictive marker of postoperative delirium in patients with acute aortic dissection | Jiang, F. Cai, M. Peng, Y. Li, S. Wang, Z. Pan, Q. Wang, C. Chen, L. Lin, Y. | Sci Rep | 2025 |
Humans Male Female Middle Aged Biomarkers/blood *Aortic Dissection/surgery/blood/complications *Delirium/blood/etiology/diagnosis Prospective Studies *Galectin 3/blood Aged *Postoperative Complications/blood/etiology/diagnosis Risk Factors ROC Curve Blood Proteins Galectins Aortic dissection Galectin-3 Postoperative delirium |
| Causal relationship between distinct sleep characteristics and delirium: A multivariable Mendelian randomization study | Jiang, C. Wang, Y. Tian, C. Lin, Z. Mu, Y. | Medicine (Baltimore) | 2025 |
Humans *Delirium/etiology/genetics/epidemiology Mendelian Randomization Analysis *Sleep/physiology Risk Factors *Sleep Wake Disorders/complications/genetics Male Female Circadian Rhythm/physiology Mendelian randomization delirium genome-wide association study sleep |
| Effects of Anxiety Focused Nursing Interventions on Anxiety, Cognitive Function and Delirium in Neurocritical Patients: A Non-Randomized Controlled Design | Jang, S. Y. Lee, M. K. | Nurs Crit Care | 2025 |
Humans *Delirium/nursing/prevention & control/epidemiology Male Female *Anxiety/nursing Republic of Korea Middle Aged Intensive Care Units Aged *Critical Care Nursing/methods *Cognition Incidence Adult anxiety cognitive function incidence of delirium neurocritical care nursing intervention programme patients in intensive care unit |
| Better Assessment of Illness Study (BASIL) II for Delirium Severity: Study Design, Variables, and Methods | Hshieh, T. T. Chapin, B. A. Mak, W. Xu, G. Schmitt, E. M. Marcantonio, E. R. Shanes, H. Heine, C. Helfand, J. Price, C. Boockvar, K. S. Metzger, E. D. Fong, T. G. Jones, R. N. Inouye, S. K. | J Geriatr Psychiatry Neurol | 2025 |
Alzheimer’s dementia and related disorders delirium delirium severity dementia validation |
| Impact of perioperative dexmedetomidine on postoperative delirium in adult undergoing cardiac surgery: A comprehensive bibliometrix and meta-analysis | Fu, Q. Sandeep, B. Li, H. Wang, B. S. Huang, X. | Asian J Psychiatr | 2025 |
Humans *Dexmedetomidine/pharmacology/administration & dosage *Cardiac Surgical Procedures/adverse effects *Hypnotics and Sedatives/pharmacology/administration & dosage *Postoperative Complications/prevention & control *Delirium/prevention & control *Emergence Delirium/prevention & control *Perioperative Care Randomized Controlled Trials as Topic Bibliometrix Cardiac surgery Dexmedetomidine Meta-analysis Postoperative delirium |
| Machine Learning Multimodal Model for Delirium Risk Stratification | Friedman, J. I. Parchure, P. Cheng, F. Y. Fu, W. Cheertirala, S. Timsina, P. Raut, G. Reina, K. Joseph-Jimerson, J. Mazumdar, M. Freeman, R. Reich, D. L. Kia, A. | JAMA Netw Open | 2025 |
Humans *Delirium/diagnosis *Machine Learning Female Male Risk Assessment/methods Aged Retrospective Studies Middle Aged Aged, 80 and over Electronic Health Records Quality Improvement |
| Neurofilament-Light Chain and Glial Fibrillary Acidic Protein as Blood-Based Delirium Risk Markers: A Multicohort Study | Ferrara, M. C. Lozano-Vicario, L. Arosio, B. D'Orlando, C. Luca, L. Ornago, A. M. Pinardi, E. Mazzola, P. Okoye, C. Gamberale, R. Remelli, F. Castellazzi, M. Zatti, G. Foti, G. Muñoz-Vázquez Á, J. Martínez-Velilla, N. Volpato, S. Bellelli, G. | Aging Dis | 2025 |
Postoperative delirium, blood-based markers, delirium detection, NfL, GFAP |
| Delirium in the cardiac intensive care unit: Determinants and prognosis | Fayssoil, A. Chen, M. Hauguel-Moreau, M. Guillaume, J. Jacota, M. Dubourg, O. Cudennec, T. Mansencal, N. | Arch Cardiovasc Dis | 2025 |
Cardiac intensive care unit Delirium Heart Prognosis |
| Implementing Standardised Delirium Screening Using the Four A's Test (4AT) in the Emergency Department: A Quality Improvement Project | Durant, D. C. Karia, P. | Cureus | 2025 |
4at acute delirium adult emergency department delirium screening locum quality improvement projects rotational training standardisation |
| Early-Career Registered Nurses' Experiences of Implementing Non-Pharmacological Interventions for Delirium Management: A Qualitative Descriptive Study | Duan, S. Casey, P. Street, M. Manias, E. Tomlinson, E. J. | Int J Nurs Pract | 2025 |
Humans *Delirium/nursing/therapy Qualitative Research Female Male Australia Focus Groups Adult *Nursing Staff, Hospital/psychology Middle Aged delirium evidence based non–pharmacological intervention nurse |
| Clinical guidelines and strategic plan for the prevention, diagnosis and treatment of delirium: The zero delirium project | de la Varga-Martínez, O. Badenes, R. Gordaliza, C. de Miguel Manso, S. Landázuri Castillo, G. E. Armenteros Aragon, C. Fernández Castro, M. Martin Santos, A. B. Lopez Herrero, R. Navarro Pérez, R. Abad Gurumeta, A. Varela Duran, M. Heredia Rodriguez, | Rev Esp Anestesiol Reanim (Engl Ed) | 2025 |
Diagnosis Postoperative delirium Prevention Treatment |
| A Prospective Nested Case-Control Study of Risk Factors for Postoperative Delirium in Elderly Patients with Colorectal Cancer | Cui, X. Cao, N. Tian, S. Liu, Y. Xiang, J. | Clin Interv Aging | 2025 |
Humans Male Female *Colorectal Neoplasms/surgery Aged Risk Factors Case-Control Studies Prospective Studies *Delirium/epidemiology/etiology *Postoperative Complications/epidemiology/etiology Middle Aged Sleep Quality Propensity Score Aged, 80 and over Logistic Models China/epidemiology colorectal cancer elderly pain level postoperative delirium prospective nested case-control study |
| Hemodynamic control during cardiopulmonary bypass and the incidence of postoperative delirium- a post hoc analysis | Claesson-Lingehall, H. Olofsson, B. Gustafson, Y. Wahba, A. Appelblad, M. Svenmarker, S. | BMC Anesthesiol | 2025 |
Humans Female Male Aged *Hemodynamics/physiology *Cardiopulmonary Bypass/adverse effects/methods Incidence *Postoperative Complications/epidemiology *Delirium/epidemiology/etiology Cardiac Surgical Procedures/methods Aged, 80 and over Cardiac surgery Cardiopulmonary bypass Delirium Neurological complication Postoperative cognitive complications Postoperative delirium |
| Perioperative risk factors for postoperative delirium after hemiarthroplasty in geriatric hip fractures: A prospective observational study | Çelen, Z. E. Özkurt, B. Kurt, M. Utkan, A. | Medicine (Baltimore) | 2025 |
Humans Male Female *Hip Fractures/surgery Aged Prospective Studies *Hemiarthroplasty/adverse effects Risk Factors *Delirium/etiology/epidemiology Aged, 80 and over *Postoperative Complications/epidemiology/etiology Length of Stay/statistics & numerical data ROC Curve Blood Glucose/analysis albumin delirium glucose hip hemiarthroplasty risk factor |
| Low-Dose Melatonin for Prevention of Delirium in Critically Ill Patients: A Multicenter, Randomized, Placebo-Controlled Feasibility Trial | Burry, L. D. Williamson, D. R. Detsky, M. E. Bernard, F. Foster, J. Mehta, S. Pinto, R. Scales, D. C. Rose, L. | Chest | 2025 |
Humans *Melatonin/administration & dosage/pharmacokinetics *Delirium/prevention & control *Critical Illness/therapy Male Female Feasibility Studies Middle Aged Aged Intensive Care Units Dose-Response Relationship, Drug delirium feasibility intensive care melatonin prevention randomized controlled trial |
| Nurses' usage of validated tools to assess for delirium in general acute care settings: A scoping review protocol | Boyd, A. Kirwan, M. Bannon, L. | HRB Open Res | 2025 |
Delirium General acute care settings Missed care Nursing Scoping review Validated assessment tools |
| Predicting delirium in acute ischemic stroke: the PREDELIS score | Berger, N. Kramer, D. Schrempf, M. Hofer, E. Pichler, A. Fandler-Höfler, S. Haidegger, M. Hatab, I. Heine, M. Jagiello, J. Koller, H. Lilek, S. Veeranki, S. Enzinger, C. Gattringer, T. Kneihsl, M. | J Neurol | 2025 |
Humans Male Aged Female *Delirium/diagnosis/etiology/epidemiology Retrospective Studies *Ischemic Stroke/complications/diagnosis/epidemiology Aged, 80 and over Middle Aged Risk Assessment Risk Factors Severity of Illness Index Acute ischemic stroke Delirium Prediction score Prevention |
| Delirium screening and alerting systems for older hospital inpatients | Benn, L. Shah, N. McKinney, A. Min, L. Aleem, I. Luzum, M. Vlisides, P. E. | BMC Health Serv Res | 2025 |
Humans *Delirium/diagnosis Aged Female Male *Mass Screening/methods Aged, 80 and over *Inpatients Electronic Health Records Hospitals, University *Geriatric Assessment/methods Decision support (clinical) Delirium Evaluation methodology Implementation science Quality improvement |
| Contemporary Prevention and Management of Postoperative Delirium in Cardiac Surgery Patients | Ali Hassan, S. M. Patel, S. K. Badross, M. S. Dhingra, N. K. Verma, R. Verma, M. Seguchi, R. Yanagawa, B. Spence, J. David Mazer, C. Alli, A. Verma, S. Arora, R. C. | Semin Thorac Cardiovasc Surg | 2025 |
Cardiac surgery Perioperative care Postoperative delirium |
| Delirium in psychiatric consultation services | Ahlers, E. | Nervenarzt | 2025 |
Cognitive disorders Delirium management Dementia Nonpharmacological techniques Psychiatric consultation and liaison service |
| Brain Health Screening in Older Surgical Patients: A Multicenter, Retrospective, Observational Analysis and Survey | Abess, A. T. Shah, N. J. Whitlock, E. L. Schroeck, H. Ron, D. Rozek, S. B. Martinez-Camblor, P. Donovan, A. L. Schenning, K. J. Deiner, S. G. | Anesth Analg | 2025 |
Cognitive impairment, screening, geriatrics screening, surgery |
| Serotonin syndrome as a cause of delirium | Adi Pranoto, E. Wong, A. B. O. | BMJ Support Palliat Care | 2025 |
Clinical decisions Delirium Drug administration Palliative Care |
| Circadian rhythm in end-of-life delirium: a secondary analysis of two randomized controlled trials | Admane, S. Pasyar, S. Bassett, R., Jr. Bruera, E. Hui, D. | J Pain Symptom Manage | 2025 |
Circadian rhythm Delirium End-of-life care Palliative Care Sundowning |
| Post-Intensive Care Syndrome and Caregiver Burden: A Post Hoc Analysis of a Randomized Clinical Trial | Ahn, S. LaNoue, M. Su, H. Moale, A. C. Scheunemann, L. P. Kiehl, A. L. Douglas, I. S. Exline, M. C. Gong, M. N. Khan, B. A. Owens, R. L. Pisani, M. A. Rock, P. Jackson, J. C. Ely, E. W. Girard, T. D. Boehm, L. M. | JAMA Netw Open | 2025 |
Humans Male Female Middle Aged *Caregivers/psychology *Critical Illness/psychology Aged Intensive Care Units *Delirium/drug therapy/psychology *Caregiver Burden/psychology/epidemiology Stress Disorders, Post-Traumatic/psychology Adult *Critical Care/psychology Haloperidol/therapeutic use |
| Association Between Neuromuscular Blockade and Its Reversal With Postoperative Delirium in Older Patients: A Hospital Registry Study | Ahrens, E. Wachtendorf, L. J. Shay, D. Tenge, T. Paschold, B. S. Rudolph, M. I. Redaelli, S. Kaiser, L. Suleiman, A. Ma, H. Fassbender, P. J. Schaefer, M. S. | Anesth Analg | 2025 |
neuromuscular blocking agents, delirium, surgery, reversal agents, CAM |
| Association Between the Highest Lactate Level on the First Postoperative Day and Postoperative Delirium in Cardiac Surgery Patients | An, R. Wu, X. Bie, D. Ding, J. Li, Y. Jia, Y. Yuan, S. Yan, F. | CNS Neurosci Ther | 2025 |
Humans Male Female *Cardiac Surgical Procedures/adverse effects/trends Aged *Lactic Acid/blood Middle Aged *Postoperative Complications/blood/epidemiology *Delirium/blood/epidemiology/etiology Incidence Retrospective Studies Postoperative Period cardiac surgery postoperative delirium risk factor the highest lactate level |
| Prediction of postoperative delirium by blood metabolome analysis | Arai, N. Sugiura, Y. Nakajima, S. Wada, M. Moriyama, S. Mimura, Y. Niinomi, K. Takayama, K. Maeda, R. Kitada, S. Fagarasan, S. Tajima, M. Boku, S. Takebayashi, M. Kato, J. Kitago, M. Kitagawa, Y. Takahashi, T. Shimizu, H. Uchida, H. Suematsu, M. Mimura, M | J Psychiatr Res | 2025 |
Humans Male Female Tryptophan/blood/metabolism Aged Middle Aged *Metabolome/physiology Metabolomics *Postoperative Complications/blood/diagnosis *Delirium/blood/diagnosis/etiology Dipeptides/blood Biomarkers/blood Delirium Kynurenine Tryptophan γ-glutamyl dipeptide |
| Incidence and factors associated with delirium in an Emergency Department | Ayón-Aguilar, J. Serrano-Vértiz, L. Quiroz-Lara, F. V. Torres-Macotela, M. | Rev Med Inst Mex Seguro Soc | 2025 |
Humans Female Male *Delirium/epidemiology/etiology/diagnosis Prospective Studies *Emergency Service, Hospital/statistics & numerical data Incidence Aged, 80 and over Aged Mexico/epidemiology Risk Factors Delirium Elderly Emergency Department |
| Circulating tsRNAs serve as potential biomarkers for predicting postoperative delirium in elderly patients receiving lower extremity orthopedic surgery | Cao, A. Zhao, R. Chen, C. Wu, C. Zhang, Y. Huang, C. Zhu, B. | Front Psychiatry | 2025 |
RT-qPCR elderly patients postoperative delirium (POD) propensity score matching (PSM) tsRNA |
| Acute Pain Management for the Older Adult | Casey, M. F. Niznik, J. | Emerg Med Clin North Am | 2025 |
Humans *Acute Pain/drug therapy/diagnosis *Pain Management/methods Aged *Analgesics/therapeutic use Emergency Service, Hospital Pain Measurement Acute pain Analgesics Emergency medicine Pain Pain assessment |
| Small vessel disease contributions to acute delirium: a pilot feasibility MRI study | Clancy, U. Cheng, Y. Jardine, C. Doubal, F. MacLullich, A. M. J. Wardlaw, J. M. | Age Ageing | 2025 |
Humans *Delirium/diagnostic imaging/epidemiology/etiology/psychology Female Feasibility Studies Male Pilot Projects Aged, 80 and over Aged Case-Control Studies *Magnetic Resonance Imaging *Cerebral Small Vessel Diseases/diagnostic imaging/complications/epidemiology Predictive Value of Tests Risk Factors Diffusion Magnetic Resonance Imaging Acute Disease cerebral small vessel diseases cerebrovascular disorders cognitive dysfunction delirium magnetic resonance imaging older people |
| Music therapy in addition to music listening for the prevention of delirium in mechanically ventilated patients | Crew, J. Abdelmonem, A. Wang, X. Harmon, C., Jr. Modrykamien, A. | Proc (Bayl Univ Med Cent) | 2025 |
Delirium length of stay mechanical ventilation music therapy sedation |
| Effect of parecoxib on postoperative delirium in patients with hyperlipidemia: a randomized, double-blind, single-center, superiority trial | Daojun, Z. Yuling, T. Yingzhe, X. Kowark, A. Coburn, M. Yue, Z. Qixin, Z. Daiying, Z. Tao, P. Xiaoxia, D. | Int J Surg | 2025 |
Humans Double-Blind Method Male Female Middle Aged *Hyperlipidemias/complications *Cyclooxygenase 2 Inhibitors/therapeutic use/administration & dosage *Isoxazoles/therapeutic use Aged *Emergence Delirium/prevention & control/epidemiology/etiology *Postoperative Complications/prevention & control/epidemiology Incidence Adult China/epidemiology *Delirium/prevention & control hyperlipidaemia inflammation parecoxib post operative delirium |
| Validation of Cerebral State Monitor Frequency Power Ratios for Detection of Delirium | DeBurlo, R. Robles, A. Salazar, S. Yang, J. MacDonald, S. Luo, A. Myers, O. Wylie, W. Quinn, D. K. | J Acad Consult Liaison Psychiatry | 2025 |
3d-cam Delirium Eeg biomarkers cerebral state monitor encephalopathy |