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Delirium, Dementia, and Adverse Outcomes

Contributed by Thiago J. Avelino-Silva, MD, PhD*; Flávia B. Garcez, MD, PhD* *Faculty of Medicine, University of São Paulo, São Paulo, Brazil Delirium results from an intricate combination of dozens of possible predisposing and precipitating factors1. Older age, functional dependence, and preexisting cognitive impairment are key determinants for its occurrence, but the latter is a […]

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Delirium Research Hub Investigator Spotlight: Miles Berger

Every other month, the Delirium Research Hub selects an investigator and research study included in the Delirium Research Hub to feature as a Spotlight Investigator. This month, we are featuring Dr. Miles Berger, MD, PhD for his study “Markers of Alzheimer’s Disease and Cognitive Outcomes after Perioperative Care (MADCO-PC).” This study investigates whether changes in […]

Tammy T. Hshieh

Does Alzheimer’s Disease and Related Dementias Modify Delirium Severity and Hospital Outcomes?

Contributed by Tammy T. Hshieh, MD MPH, Associate Physician at Brigham and Women’s Hospital, Harvard Medical School and Research Faculty at the Aging Brain Center, Hebrew Senior Life NIDUS supports junior researchers by seeding pilot grants. I was fortunate to have received such an award in 2017. At the time, I had recently completed a […]

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Interaction of Delirium and Dementia on Cognitive Decline

The differences between delirium and dementia can be difficult to spot. If an elderly man with Alzheimer’s disease tends to become confused or agitated in the evening (a condition often known as “sundowning”) is his behavior dementia- or delirium-related? Moreover, what are the biological bases that differ between delirium and dementia? New research published in […]