What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Sex-Specific Validity of the PRE-DELIRIC Model and the E-PRE-DELIRIC Model for Predicting Delirium in Patients After Cardiac Surgery
- Authors
- Cho Msn, E. J. Kim, M. S. Park Msn, J.
- Year
- 2024
- Journal
- J Cardiovasc Nurs
- Abstract
BACKGROUND: Several risk prediction models are used in intensive care units (ICUs) to detect delirium risk. OBJECTIVE: The aim of this study was to compare the sex-specific validity of the Prediction of Delirium in ICU patients (PRE-DELIRIC) and Early Prediction of Delirium in ICU patients (E-PRE-DELIRIC) models for predicting delirium in ICU patients after cardiac surgery. METHODS: Retrospective data from electronic medical records of ICU patients who underwent cardiac surgery between January 2019 and December 2022 were examined. Both models were evaluated using sensitivity, specificity, and positive and negative predictive values based on the highest Youden index for female and male patients. Receiver operating characteristic curve analysis was performed. RESULTS: Delirium incidence was 30.7% and 27.5% in female and male patients, respectively. In the PRE-DELIRIC model, the highest Youden index scores for female and male patients were 67.00 and 57.54, respectively, with sensitivities and specificities of 61% and 88%, and 72% and 79%, respectively. In the E-PRE-DELIRIC model, the highest scores for female and male patients were 14.25 and 14.05, with sensitivities and specificities of 78% and 50%, and 70% and 53%, respectively. The area under the curve of the PRE-DELIRIC model for female and male patients was 0.77 and 0.78, respectively, and that of the E-PRE-DELIRIC model was 0.67 and 0.63, respectively. CONCLUSIONS: The PRE-DELIRIC model showed higher specificity and was more reliable for male patients, whereas the E-PRE-DELIRIC model demonstrated better sensitivity for female patients due to its inclusion of more female-sensitive factors. A combined approach is recommended for improved reliability and validity in delirium risk assessment in clinical settings.
- PMID
PMID: 39688834
- Keywords
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Factors Influencing Nurses' Knowledge About Delirium in Acute Care Settings in Hail Region, Saudi Arabia: A Cross-Sectional Study | Almoliky, M. A. Alkubati, S. A. Alsaqri, S. H. Saleh, K. A. Sultan, M. A. Al-Ahdal, S. A. Balawi, A. M. Moatakef, H. I. | Risk Manag Healthc Policy | 2024 |
Saudi Arabia, delirium, intensive care unit, knowledge |
| Association of remimazolam with delirium and cognitive function: A systematic review and meta-analysis of randomised controlled trials | Arias, J. A. Wegner, G. R. M. Wegner, B. F. M. Silva, L. S. Bezerra, F. J. L. Filardi, R. G. M. | Eur J Anaesthesiol | 2024 | |
| The Association Between Delirium Upon Admission to a Rehabilitation Hospital and Motor Rehabilitation Outcomes Among Hip Fracture Surgery Patients: A Historical Cohort Study | Balzer, A. Novak, A. M. Marom, P. Schwartz, O. Brik, M. Slutzki, K. Heruti, R. J. Dankner, R. | J Clin Med | 2024 |
delirium, geriatrics, hip fracture, older adults, rehabilitation |
| Disorientation as a delirium feature in non-intubated patients: development and evaluation of diagnostic accuracy of the 'Confusion Assessment Method for Intermediate Care Unit' (CAM-IMC) - a prospective cohort study | Beyer, L. P. Gathen, L. V. Z. Rayah, B. E. Dewald, O. Zieschang, T. Diers, A. Ely, E. W. Guenther, U. | BMC Anesthesiol | 2024 |
Humans Prospective Studies Male Female Aged *Confusion/diagnosis Middle Aged Cohort Studies *Delirium/diagnosis Postoperative Complications/diagnosis Sensitivity and Specificity Cardiac Surgical Procedures Intensive Care Units Reproducibility of Results Cam-icu Cam-imc Delirium Disorientation Non-intubated Pod |
| Increased cell-free DNA in CSF and serum of hip fracture patients with delirium | Bratseth, V. Watne, L. O. Neerland, B. E. Halaas, N. B. Pollmann, C. T. Karabeg, A. Odegaard, O. T. Sydnes, K. Zetterberg, H. Seljeflot, I. Helseth, R. | Brain Commun | 2025 |
cell-free DNA, delirium, neurofilament light chain, neuroinflammation, neutrophil extracellular traps |
| Haloperidol dopamine receptor occupancy and antagonism correspond to delirium agitation scores and EPS risk: A PBPK-PD modeling analysis | Burkat, P. M. | J Psychopharmacol | 2025 |
Antagonism, Rass, delirium, haloperidol, occupancy |
| Identifying Symptoms of Delirium from Clinical Narratives Using Natural Language Processing | Chen, A. Paredes, D. Yu, Z. Lou, X. Brunson, R. Thomas, J. N. Martinez, K. A. Lucero, R. J. Magoc, T. Solberg, L. M. Snigurska, U. A. Ser, S. E. Prosperi, M. Bian, J. Bjarnadottir, R. I. Wu, Y. | Proc (IEEE Int Conf Healthc Inform) | 2024 |
clinical natural language processing, deep learning, delirium, medication information extraction, named entity recognition |
| Association between the geriatric nutritional risk index and postoperative delirium in gastric surgery patients: an analysis of the MIMIC-IV database | Chen, Y. Chen, H. Zhuang, Y. Wang, Y. Dai, Z. | BMC Anesthesiol | 2024 |
Humans Female Male Aged *Postoperative Complications/epidemiology *Databases, Factual Middle Aged *Nutritional Status Malnutrition/epidemiology Delirium/epidemiology/etiology Geriatric Assessment/methods Risk Factors Nutrition Assessment Incidence Stomach/surgery Aged, 80 and over Gnri Gastric surgery MIMIC-IV database Nutritional status Postoperative delirium |
| Sex-Specific Validity of the PRE-DELIRIC Model and the E-PRE-DELIRIC Model for Predicting Delirium in Patients After Cardiac Surgery | Cho Msn, E. J. Kim, M. S. Park Msn, J. | J Cardiovasc Nurs | 2024 | |
| Covert perioperative strokes in older patients having non-cardiac surgery (PRECISION): a prospective cohort analysis | Cui, Q. Zhao, W. Chen, H. Ren, Y. Yin, X. Zheng, M. Li, M. Wang, J. Wang, J. Zeng, M. Li, S. Zhang, K. Wu, X. Zhou, L. Jiao, Y. Sessler, D. I. Mi, W. Peng, Y. | Anesthesiology | 2024 | |
| Intraoperative Electroencephalogram Frontal Low Alpha Power for Predicting Postoperative Delirium in Elderly Patients after Orthopedic Surgery: A Prospective Cohort Study | Dai, Y. Shen, C. Shi, K. Liu, Q. Qiu, X. Sun, J. | Ann Ital Chir | 2024 |
Humans Prospective Studies Aged *Electroencephalography Male Female *Delirium/etiology/diagnosis/epidemiology *Postoperative Complications/epidemiology *Orthopedic Procedures/adverse effects Incidence Cohort Studies Middle Aged Predictive Value of Tests Aged, 80 and over Alpha Rhythm |
| Microglial activation and neuroinflammation in acute and chronic cognitive deficits in sepsis | Denver, P. Cunningham, C. | Neuropharmacology | 2024 |
Cognitive Cytokines Delirium Encephalopathy Il-1 Microglia Sepsis Systemic inflammation Tnf |
| The Role of Sleep Apnea in Postoperative Neurocognitive Disorders Among Older Noncardiac Surgery Patients: A Prospective Cohort Study | Devinney, M. J. Spector, A. R. Wright, M. C. Thomas, J. Avasarala, P. Moretti, E. Dominguez, J. E. Smith, P. J. Whitson, H. E. Veasey, S. C. Mathew, J. P. Berger, M. | Anesth Analg | 2025 |
Humans Female Male Prospective Studies Aged Middle Aged *Sleep Apnea, Obstructive/diagnosis/epidemiology/complications/surgery Risk Factors Postoperative Complications/etiology/diagnosis/epidemiology Severity of Illness Index Aged, 80 and over Postoperative Cognitive Complications/diagnosis/epidemiology/etiology Cognition Cohort Studies Neurocognitive Disorders/etiology/diagnosis/epidemiology Surgical Procedures, Operative/adverse effects Sleep Apnea Syndromes/diagnosis/complications/epidemiology Time Factors Incidence |
| Assessment of cognitive function after surgery for colorectal cancer-a scoping review | Ehrencrona, C. Levenskog, R. Angenete, E. | BMJ Open | 2024 |
Humans *Colorectal Neoplasms/surgery Cognition Cognitive Dysfunction/etiology Postoperative Cognitive Complications/etiology/epidemiology Postoperative Complications/epidemiology/psychology/etiology Risk Factors Patient Reported Outcome Measures Colorectal surgery Delirium & cognitive disorders Systematic Review |
| The association between delirium and falls in older adults in the community: a systematic review and meta-analysis | Eost-Telling, C. McNally, L. Yang, Y. Shi, C. Norman, G. Ahmed, S. Poku, B. Money, A. Hawley-Hague, H. Todd, C. J. Shenkin, S. D. Vardy, Erlc | Age Ageing | 2024 |
Humans *Accidental Falls/statistics & numerical data *Delirium/epidemiology/diagnosis Aged *Independent Living Risk Factors Risk Assessment Aged, 80 and over Female Male Middle Aged community delirium falls older adults older people systematic review |
| Evaluation of Delirium Risk Factors in Intensive Care Patients | Erel, S. Macit Aydın, E. Nazlıel, B. Karabıyık, L. | Turk J Anaesthesiol Reanim | 2024 |
Cognition disorders, critical care, delirium, incidence, risk |
| Anticholinergic Exposure, Drug Dose and Postoperative Delirium: Comparison of Dose-Related and Non-Dose-Related Anticholinergic Burden Scores in a Retrospective Cohort Study of Older Orthopaedic and Trauma Surgery Patients | Geßele, C. Rémi, C. Smolka, V. Dimitriadis, K. Amann, U. Saller, T. Strobach, D. | Drugs Aging | 2024 |
Humans Retrospective Studies Aged Male Female *Delirium *Cholinergic Antagonists/adverse effects/administration & dosage *Postoperative Complications *Dose-Response Relationship, Drug Aged, 80 and over Orthopedic Procedures/adverse effects Risk Factors Cohort Studies Wounds and Injuries/surgery Acute Care Surgery |
| Evaluating the impact of Benson's relaxation technique on anxiety and delirium among coronary artery bypass graft surgery patients | Golchoubi, A. Miri, K. Vagheei, S. Hajiabadi, F. Kahrom, M. Behnam Vashani, H. R. | J Cardiothorac Surg | 2024 |
Humans *Coronary Artery Bypass/psychology/adverse effects Male Female *Relaxation Therapy/methods Middle Aged *Anxiety/etiology/prevention & control *Delirium/prevention & control/etiology Aged Postoperative Complications/psychology/prevention & control Anxiety Benson’s relaxation Coronary artery bypass graft surgery Delirium |
| A Nurse-Initiated Protocol for Interprofessional Management of Changed Behaviours in Hospital Patients With Dementia and/or Delirium: A Modified e-Delphi Study | Graham, F. A. Ossenberg, C. Henderson, A. | J Adv Nurs | 2025 | |
| Incidence and Associated Factors of Postoperative Delirium in Adults Undergoing Cardiac Surgery With Cardiopulmonary Bypass: A Prospective Cohort Study | Guo, Y. Li, C. Mu, Y. Wu, T. Lin, X. | J Clin Nurs | 2024 |
associated factors, cardiac surgery, cardiopulmonary bypass, incidence, postoperative delirium |
| Quantitative electroencephalography predicts postoperative delirium in adult cardiac surgical patients from a prospective observational study | Guo, Z. Wan, W. Liu, W. Liu, L. Yang, Y. Yang, C. Cui, X. | Sci Rep | 2024 |
Humans *Electroencephalography/methods Male Female Prospective Studies *Delirium/diagnosis/etiology Aged Middle Aged *Cardiac Surgical Procedures/adverse effects *Postoperative Complications/diagnosis/etiology ROC Curve Prognosis Cardiac surgery Dfa Delirium Mse Peak or valley value qEEG |
| Complementary effects of postoperative delirium and frailty on 30-day outcomes in spine surgery | Gupta, N. K. Prvulovic, S. T. Zoghi, S. Chmait, H. R. Covell, M. M. Sabet, C. J. DeGenova, D. T. Moisi, M. D. Schmidt, M. H. Bowers, C. A. | Spine J | 2024 |
Frailty, Postoperative delirium, Risk Analysis Index, Spine |
| Causal relationship between mitochondrial function and delirium: a bidirectional two-sample Mendelian randomisation analysis | Han, Y. Y. Tian, Y. Song, L. F. Zhou, Q. Rong, Y. H. Qin, Z. S. | Psychogeriatrics | 2025 |
Humans *Mendelian Randomization Analysis *Delirium/genetics *Mitochondria/genetics/metabolism Risk Factors Alcohol Withdrawal Delirium/genetics Mendelian randomisation association causally delirium mitochondria mitochondrial function |
| Delirium Motor Subtypes and Severity of Physical Symptoms in Patients with Advanced Cancer in Inpatient Hospice/Palliative Care Units: A Multicenter Prospective Cohort Study | Hasegawa, T. Mori, M. Yamaguchi, T. Imai, K. Matsuda, Y. Maeda, I. Hatano, Y. Yokomichi, N. Hamano, J. Morita, T. | J Palliat Med | 2024 |
delirium, dyspnea, neoplasm, pain, palliative care |
| Associations between oral frailty, oral microbiota composition, and postoperative delirium in older adult patients | Hu, X. Y. Duan, H. W. Wang, L. Y. Liu, Q. F. Yao, H. Ma, D. Q. Wang, D. X. Yang, J. J. Ji, M. H. | J Am Geriatr Soc | 2024 |
frailty, oral healthy, oral microbiota, postoperative delirium |
| Risk of drug-induced delirium in older patients- a pharmacovigilance study of FDA adverse event reporting system database | Jia, B. Zhou, S. Li, J. Wan, L. Zhou, Y. Cui, Y. | Expert Opin Drug Saf | 2025 |
Humans *Adverse Drug Reaction Reporting Systems/statistics & numerical data *Delirium/chemically induced/epidemiology *Pharmacovigilance Aged *United States Food and Drug Administration United States *Drug-Related Side Effects and Adverse Reactions/epidemiology *Databases, Factual Risk Factors Aged, 80 and over Male Female Age Factors Prevalence ADEs Fares Older patients drug-induced delirium pharmacovigilance |
| Nursing Practices for Preventing Delirium in Patients with Cancer with Prognoses of Months and Weeks: A Multi-Site Cross-Sectional Study in Japan | Kanno, Y. Nakano, K. Kajiwara, K. Kobayashi, M. Morikawa, M. Matsuda, Y. Kako, J. | Am J Hosp Palliat Care | 2025 |
cancer, cross-sectional studies, delirium, non-pharmacological therapy, nursing practice, palliative care |
| Association of post-stroke delirium with short-term trajectories of cognition | Klimiec-Moskal, E. Pera, J. Slowik, A. Dziedzic, T. | J Psychosom Res | 2024 |
Cognition, Delirium, Stroke |
| Postoperative delirium following total joint arthroplasty: epidemiology, risk factors, and associated complications | Knebel, A. Singh, M. Rasquinha, R. Daher, M. Nassar, J. E. Hanna, J. Cohen, E. M. Diebo, B. G. Daniels, A. H. | Hip Int | 2024 |
Complications, epidemiology, postoperative delirium, risk factors, total hip arthroplasty, total knee arthroplasty |
| The possible interaction between tryptophan and its metabolites with delirium in older patients with critical illnesses | Kollu, K. Kurku, H. Unlu, A. Ecer, B. Guney, I. Kizilarslanoglu, M. C. | Eur Geriatr Med | 2024 |
Humans Female Male *Tryptophan/metabolism *Delirium/metabolism Aged Prospective Studies Aged, 80 and over *Kynurenine/analogs & derivatives/metabolism Middle Aged *Critical Illness *Kynurenic Acid/metabolism Intensive Care Units Quinolinic Acid/metabolism 3-Hydroxyanthranilic Acid/metabolism Delirium Intensive care unit Kynurenine pathway Older patient Tryptophan |
| Association Between Verbal Communication With Families and Delirium in Mechanically Ventilated Patients: A Retrospective Study | Kudou, K. Okura, K. Satoh, K. | Cureus | 2024 |
communication critical care critical care nursing delirium family intensive care unit intermittent positive-pressure ventilation |
| The autonomous nervous system and the cholinergic anti-inflammatory reflex in postoperative neurocognitive disorders | Lammers-Lietz, F. Spies, C. Maggioni, M. A. | Curr Opin Anaesthesiol | 2025 |
Humans *Vagus Nerve/physiopathology *Autonomic Nervous System/physiopathology/immunology/drug effects Heart Rate/drug effects Postoperative Complications/prevention & control/etiology/immunology/diagnosis Postoperative Cognitive Complications/prevention & control/etiology/diagnosis/immunology Animals Reflex/drug effects Delirium/prevention & control/etiology/diagnosis/immunology Neurocognitive Disorders/etiology/prevention & control/diagnosis/immunology |
| Cerebral oximetry index indicates delirium or stroke after carotid endarterectomy: An observational study | Li, M. Ma, T. Yin, X. Zhang, X. Long, T. Zeng, M. Wang, J. Cui, Q. Li, S. Sessler, D. I. Wang, R. Peng, Y. | J Clin Anesth | 2024 |
Anesthesia, Carotid endarterectomy, Cerebral autoregulation, Cerebral oximetry index, Delirium, Stroke |
| Effects of glucocorticoids on postoperative delirium in patients undergoing elective non-cardiac surgery:A systematic review and meta-analysis | Li, Z. Lu, J. Wang, D. Han, L. | Heliyon | 2024 |
Delirium, Glucocorticoids, Meta-analysis, Non-cardiac surgery, Postoperative |
| Application of laboratory frailty index in predicting delirium in elderly patients with community-acquired pneumonia | Liao, J. Shen, X. Du, Z. Miao, L. | Front Aging | 2024 |
community-acquired pneumonia, delirium, elderly, frailty, malnutrition |
| Esketamine and neurocognitive disorders in adult surgical patients: a meta-analysis | Lin, X. Liu, X. Huang, H. Xu, X. Zhang, T. Gao, J. | BMC Anesthesiol | 2024 |
Humans *Ketamine/administration & dosage *Anesthesia, General/methods *Randomized Controlled Trials as Topic Adult Postoperative Cognitive Complications/prevention & control Postoperative Complications/prevention & control Neurocognitive Disorders/prevention & control Postoperative Nausea and Vomiting/prevention & control/epidemiology Esketamine Meta-analysis Perioperative neurocognitive disorders Postoperative delirium |
| Assessment of sleep quality using cardiopulmonary coupling and its predictive value for delirium in ICU patients | Liu, C. Ji, X. Lu, J. Zhong, L. Hu, J. Wang, Y. Zhou, Q. Xie, B. | Sleep Med | 2024 |
Cardiopulmonary coupling (CPC), Delirium, Intensive care unit (ICU), Sleep |
| Causal Associations Between Sleep Traits and Delirium: A Bidirectional Two-Sample Mendelian Randomization Study | Liu, H. Zhang, Z. He, Y. Ding, L. Wu, T. Wang, Y. Ma, W. | Nat Sci Sleep | 2024 |
Mendelian randomization analysis, delirium, genome-wide association studies, sleep traits |
| Advancements in the Management of Fragility Fractures in Orthopaedic Patients | Locke, S. Doonan, J. Jones, B. | Cureus | 2024 |
clinical frailty scale fragility fractures frailty locking plate fixation minimally invasive plate osteosynthesis (mipo) osteoporosis pelvic fractures peripheral nerve block regional anaesthesia vertebral fracture |
| Effect of Low-Dose Esketamine on Postoperative Delirium in Elderly Patients Undergoing Total Hip or Knee Arthroplasty: A Randomized Controlled Trial | Ma, C. B. Zhang, C. Y. Gou, C. L. Liang, Z. H. Zhang, J. X. Xing, F. Yuan, J. J. Wei, X. Zhang, Y. B. Wang, Z. Y. | Drug Des Devel Ther | 2024 |
Humans *Ketamine/administration & dosage Aged *Arthroplasty, Replacement, Knee/adverse effects Male *Arthroplasty, Replacement, Hip/adverse effects Female *Delirium/prevention & control Double-Blind Method Postoperative Complications/prevention & control Dose-Response Relationship, Drug Aged, 80 and over arthroplasty delirium esketamine |
| Intraoperative Dexmedetomidine Infusion Improved Postoperative Sleep Quality and Melatonin Secretion in Patients Undergoing Elective Thoracoscopic Lung Surgery: A Prospective, Randomized Study | Mei, B. Yang, X. Yang, Y. Y. Weng, J. T. Cao, S. D. Yang, R. Xu, G. | Nat Sci Sleep | 2024 |
dexmedetomidine, melatonin, postoperative sleep quality |
| Characteristics of patients who die in an acute palliative care unit | Mercadante, S. Cascio, A. L. Casuccio, A. | Support Care Cancer | 2024 |
Humans *Palliative Care/methods Male Female *Neoplasms/complications/therapy/mortality Aged Middle Aged Prospective Studies Risk Factors Aged, 80 and over Cachexia/etiology/therapy Adult Multivariate Analysis Acute palliative care unit Advanced cancer Mortality Palliative care |
| A Secondary Analysis of the Prevalence and Clinical Profile of Psychiatric Referrals of Delirium in a Tertiary Care Hospital in Central India | Mishra, S. Mudgal, V. Mathur, R. Niranjan, V. Pal, V. | Cureus | 2024 |
central India, delirium, India, outcome, prevalence, tertiary care hospital, variables |
| 'The upside-down' healthcare professional students' experiences of delirium: an all-Ireland focus group study | Mitchell, G. Graham, M. Murphy, J. Barry, H. E. Coffey, A. Boland, P. Anderson, T. Tuohy, D. Birch, M. Tierney, A. Stark, P. McCurtin, A. McMahon, J. Creighton, L. Henderson, E. Craig, S. McConnell, H. Guttridge, H. Cook, L. Cunningham, E. Curran, G. M. B | BMC Med Educ | 2024 |
Humans *Delirium/therapy *Focus Groups Ireland *Qualitative Research Male Female Attitude of Health Personnel Students, Health Occupations/psychology Interprofessional Relations Adult Patient Care Team Students, Medical/psychology Allied health student Delirium Education Healthcare Interprofessional education Medical student Nursing student Pharmacy student |
| Relevance of Preoperative Cognitive Impairment for Predicting Postoperative Delirium in Surgical Medicine: A Prospective Cohort Study | Moellmann, H. L. Alhammadi, E. Olbrich, P. Frohnhofen, H. | Geriatrics (Basel) | 2024 |
cognitive impairment, geriatric assessment, postoperative delirium, surgery |
| Accumulating the key proteomic signatures associated with delirium: Evidence from systematic review | Mosharaf, M. P. Alam, K. Gow, J. Mahumud, R. A. | PLoS One | 2024 |
Humans, *Delirium/diagnosis/metabolism, *Proteomics/methods, *Biomarkers/metabolism |
| Predicting mortality of elderly patients undergoing open heart surgery with delirium using sequential organ failure assessment (SOFA), multi-organ dysfunction (MODS), and logistic organ dysfunction system (LODS) scores | Mousabeygi, E. Rahmati, M. Salari, N. Jalali, R. | Geriatr Nurs | 2024 |
Humans Aged Male Female *Delirium/mortality Prospective Studies *Multiple Organ Failure/mortality *Cardiac Surgical Procedures/mortality *Organ Dysfunction Scores Aged, 80 and over Predictive Value of Tests Sensitivity and Specificity Delirium Lods Mods Open heart surgery Organ dysfunction scores Sofa |
| The Prediction of Postoperative Delirium Using the Preoperative Assessments of Frailty and Cognitive Impairment in Aged Patients | Ni, P. Liu, Z. Yang, J. Xie, Y. Wang, S. | Clin Interv Aging | 2024 |
Humans Male Female Aged *Delirium/epidemiology/diagnosis *Cognitive Dysfunction/epidemiology *Postoperative Complications/epidemiology *Frailty/diagnosis Middle Aged Length of Stay Geriatric Assessment/methods Aged, 80 and over Risk Factors Intensive Care Units ROC Curve Risk Assessment Incidence Frail Elderly cognitive impairment frailty postoperative complication postoperative delirium surgery |
| Prognostic Implications of Delirium After Left Ventricular Assist Device Implantation: A Retrospective Study | Noufi, P. Anderson, K. M. Crowell, N. White, Y. Molina, E. Rao, S. D. Groninger, H. | J Acad Consult Liaison Psychiatry | 2024 |
Humans *Heart-Assist Devices/adverse effects *Delirium/epidemiology Female Male Retrospective Studies Middle Aged Prognosis *Hospital Mortality Aged *Length of Stay Adult Patient Readmission/statistics & numerical data Heart Failure Postoperative Complications/epidemiology Lvad delirium morbidity mortality |
| Valproic Acid for Hyperactive Delirium and Agitation in Critically Ill Patients | Nuti, O. Merchan, C. Ahuja, T. Arnouk, S. Papadopoulos, J. Katz, A. | J Intensive Care Med | 2024 |
agitation, delirium, sedatives, valproic acid |
| Effect of remimazolam on postoperative delirium and cognitive function in adults undergoing general anesthesia or procedural sedation: a meta-analysis of randomized controlled trials | Park, J. I. Na, H. S. Kim, J. N. Ryu, J. H. Jang, H. Shin, H. J. | Korean J Anesthesiol | 2025 |
Cognitive function, Delirium, Hypotension, Postoperative nausea and vomiting, Propofol, Remimazolam |
| Incidence and assessment of delirium following open cardiac surgery: a systematic review and meta-analysis | Petersson, N. B. Hansen, M. H. Hjelmborg, J. V. B. Instenes, I. Christoffersen, A. S. Larsen, K. L. Schmidt, H. Riber, L. P. S. Norekvål, T. M. Borregaard, B. | Eur J Cardiovasc Nurs | 2024 |
Humans *Delirium/epidemiology/etiology/diagnosis *Cardiac Surgical Procedures/adverse effects Incidence *Postoperative Complications/epidemiology/diagnosis Cardiac surgery Delirium Validated assessment tools |
| Severity of Symptoms as an Independent Predictor of Poor Outcomes in Patients with Advanced Cancer Presenting to the Emergency Department: Secondary Analysis of a Prospective Randomized Study | Qdaisat, A. Stroh, E. Reyes-Gibby, C. Wattana, M. K. Viets-Upchurch, J. Li, Z. Page, V. D. Fatima, H. Chaftari, P. Elsayem, A. | Cancers (Basel) | 2024 |
Mdasi advanced cancer delirium emergency department palliative care symptom |
| Efficacy of Cerebral Oxygen Saturation Monitoring for Perioperative Neurocognitive Disorder in Adult Non-cardiac Surgical Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials | Qiu, L. Ma, Y. Ge, L. Zhou, H. Jia, W. | World Neurosurg | 2024 |
Near-infrared spectroscopy Perioperative neurocognitive disorders Postoperative cognitive decline Postoperative cognitive dysfunction Postoperative delirium Regional cerebral oxygen saturation |
| Validating the Fluctuating Mental Status Evaluation in Neurocritically Ill Patients With Acute Stroke | Reznik, M. E. Margolis, S. A. Andrews, N. Basso, C. Mintz, N. Varga, S. Snitz, B. E. Girard, T. D. Shutter, L. A. Ely, E. W. Jones, R. N. | Crit Care Med | 2024 |
Humans Male Female Middle Aged *Delirium/diagnosis Prospective Studies Aged *Stroke/complications/diagnosis *Critical Illness Aged, 80 and over Reproducibility of Results Intensive Care Units Sensitivity and Specificity Mental Status and Dementia Tests/standards |
| Navigating the Surgical Pathway for Frail, Older Adults Undergoing Colorectal Surgery | Roo, A. C. Ivatury, S. J. | Clin Colon Rectal Surg | 2025 |
frailty, older adults, prehabilitation, shared decision-making, surgery |
| Sex specific differences in short-term mortality after ICU-delirium | Schreiber, N. Eichlseder, M. Orlob, S. Klivinyi, C. Zoidl, P. Pichler, A. Eichinger, M. Fandler-Höfler, S. Scholz, L. Baumgartner, J. Schörghuber, M. Eller, P. | Crit Care | 2024 |
Humans Male Female *Delirium/mortality Retrospective Studies *Intensive Care Units/organization & administration/statistics & numerical data Middle Aged Aged *Propensity Score Sex Factors Cohort Studies Proportional Hazards Models Critical Illness/mortality Hospital Mortality Adult Risk Factors ICU-delirium Mortality Personalized ICU-care Sex differences |
| Alpha2 Agonist Use in Critically Ill Adults: A Focus on Sedation and Withdrawal Prevention | Schuler, A. Yoon, C. H. Caffarini, E. Heine, A. Meester, A. Murray, D. Harding, A. | J Pharm Pract | 2025 |
Humans *Critical Illness *Adrenergic alpha-2 Receptor Agonists/administration & dosage/therapeutic use *Hypnotics and Sedatives/administration & dosage/pharmacokinetics *Dexmedetomidine/administration & dosage/therapeutic use *Substance Withdrawal Syndrome/drug therapy/prevention & control Clonidine/administration & dosage/therapeutic use Adult Delirium/prevention & control/drug therapy Guanfacine/administration & dosage/therapeutic use clonidine dexmedetomidine guanfacine sedation withdrawal |
| Psychological interventions for patients with delirium in intensive care: A scoping review protocol | Shaikh, M. Wade, D. M. King, L. Mackay, L. Symes, I. Syeda, A. Greenburgh, A. | PLoS One | 2024 |
Humans *Critical Care/methods/psychology Critical Illness/psychology *Delirium/therapy/psychology *Intensive Care Units Review Literature as Topic |
| Daily automated prediction of delirium risk in hospitalized patients: Model development and validation | Shaw, K. M. Shao, Y. P. Ghanta, M. Junior, V. M. Kimchi, E. Y. Houle, T. T. Akeju, O. Westover, M. B. | JMIR Med Inform | 2024 |
Humans *Glycocalyx/metabolism/drug effects Male *Cardiopulmonary Bypass/adverse effects Female Prospective Studies Middle Aged *Ringer’s Lactate/administration & dosage/pharmacology Aged Sodium Bicarbonate/administration & dosage/pharmacology Ringer’s Solution/administration & dosage/pharmacology Cardiac Surgical Procedures/adverse effects Cohort Studies cardiopulmonary bypass endothelial glycocalyx postoperative recovery sodium bicarbonate Ringer’s solution |
| Intraoperative Use of Sodium Bicarbonate Ringer's Solution Instead of Sodium Lactate Ringer's Solution to Reduce Endothelial Glycocalyx Degradation and Improve Postoperative Recovery During Cardiopulmonary Bypass Cardiac Surgery: A Single-Center Prospecti | Shi, Y. Shi, Y. Tao, Y. Xu, B. Wang, X. Xie, Y. Zhang, M. | Drug Des Devel Ther | 2024 |
Humans *Glycocalyx/metabolism/drug effects Male *Cardiopulmonary Bypass/adverse effects Female Prospective Studies Middle Aged *Ringer’s Lactate/administration & dosage/pharmacology Aged Sodium Bicarbonate/administration & dosage/pharmacology Ringer’s Solution/administration & dosage/pharmacology Cardiac Surgical Procedures/adverse effects Cohort Studies cardiopulmonary bypass endothelial glycocalyx postoperative recovery sodium bicarbonate Ringer’s solution |
| The effect of toluene sulfonic acid remimazolam on postoperative delirium in elderly patients undergoing painless bronchoscopy | Shi, Y. Zhang, L. Diao, Y. Zhao, M. | Sci Rep | 2024 |
Humans Aged Male Female *Bronchoscopy/methods/adverse effects *Benzodiazepines/adverse effects/therapeutic use *Postoperative Complications *Delirium/diagnosis Hypnotics and Sedatives/adverse effects Aged, 80 and over Propofol/adverse effects/administration & dosage/therapeutic use Elderly patients Painless bronchoscopy Remimazolam |
| Covert Critical Illness Encephalopathy: Impairments That Escape Detection by Guideline Recommended, Protocolized Assessments | Shirodkar, R. Bourgeois, I. J. Kim, M. Kimchi, E. Y. Liotta, E. M. Maas, M. B. | Crit Care Med | 2024 | |
| Delirium due to any cause is associated with higher resource utilization in patients undergoing liver transplantation: analysis of the National Inpatient Sample | Singh, C. Billing, H. S. Bhupal, S. S. Kohli, I. Sohal, A. Roytman, M. | Eur J Gastroenterol Hepatol | 2025 |
Humans *Liver Transplantation *Delirium/epidemiology/etiology Male Female Middle Aged *Hospital Mortality United States/epidemiology *End Stage Liver Disease/surgery/complications Aged Length of Stay Databases, Factual Prevalence Adult Health Resources/statistics & numerical data Postoperative Complications/epidemiology/etiology Risk Factors Retrospective Studies |
| Intraoperative high and low blood pressures are not associated with delirium after cardiac surgery: A retrospective cohort study | Singh, M. Spence, J. Shah, K. Duncan, A. E. Kimmaliardjuk, D. Sessler, D. I. Alfirevic, A. | J Clin Anesth | 2025 |
Blood Pressure *Hypotension/epidemiology/etiology Intraoperative Period *Emergence Delirium/epidemiology Humans Male Female Middle Aged Aged Retrospective Studies *Cardiopulmonary Bypass/adverse effects Risk Anesthesia Cardiac surgery Intraoperative hypertension Intraoperative hypotension Postoperative delirium Time weighted average mean arterial pressure |
| The effectiveness of postoperative delirium prevention, diagnosis, and intervention protocol in patients monitored in the intensive care unit after cardiac surgery: a quasi-experimental study | Söylemez, G. K. Bulut, H. | BMC Nurs | 2024 |
Cardiac surgery, Care protocol, Delirium management, Nursing |
| Neuropsychiatric complications in chronic kidney disease: Role of gender, clinical, and sociodemographic factors | Tesia, S. S. Nongpiur, A. Barman, B. Lyngdoh, M. Prithviraj, M. Roy, D. Das, J. | J Family Med Prim Care | 2024 |
Anxiety, chronic kidney disease, cognitive impairment, depression, gender |
| Delirium following total hip or knee arthroplasty: A retrospective, single-center study | Tomite, T. Saito, H. Kijima, H. Hatakeyama, Y. Tazawa, H. Wachi, T. Miyakoshi, N. | J Orthop Sci | 2024 |
Arthroplasty, Delirium, Pain control |
| Ambient pollution at hip fracture units and impact on mortality and post-operative delirium: A hormetic effect? | Uzoigwe, C. E. Bin Qadir, R. M. A. Daoub, A. | PLoS One | 2024 |
Humans *Hip Fractures/mortality/surgery *Particulate Matter/analysis/adverse effects *Delirium/etiology/mortality Aged *Air Pollution/adverse effects/analysis Female Nitrogen Dioxide/analysis/adverse effects Male Postoperative Complications/mortality/etiology/epidemiology Aged, 80 and over United Kingdom/epidemiology Air Pollutants/adverse effects/analysis Environmental Exposure/adverse effects |
| Delirium-like symptomatology in community-dwelling older adults with dementia | Vickers, J. K. Wang, D. Yefimova, M. Armah, H. Flood, K. Pickering, C. E. Z. | Psychogeriatrics | 2025 |
Humans, *Delirium/epidemiology/diagnosis, Female, Male, *Dementia/epidemiology/diagnosis, Aged, *Caregivers/psychology, *Independent Living, Aged, 80 and over, Prevalence, Longitudinal Studies, community‐dwelling, delirium, dementia, family caregiver |
| Feasibility of Alerting Systems and Family Care Partner Support for Postoperative Delirium Prevention | Vlisides, P. E. Runstadler, N. Martinez, S. Ragheb, J. W. Mentz, G. Leis, A. Schoettinger, A. Hickey, K. McKinney, A. Brooks, J. Zierau, M. Norcott, A. Mody, L. Inouye, S. K. Avidan, M. S. Min, L. | J Neurosurg Anesthesiol | 2024 | |
| Different doses of dexmedetomidine combined with propofol for older adults undergoing cardiac surgery: the impact on postoperative delirium | Wang, H. Han, H. Leng, Y. Yao, J. | J Int Med Res | 2024 |
Humans *Dexmedetomidine/administration & dosage/therapeutic use/adverse effects *Propofol/administration & dosage/adverse effects Aged Female Male *Cardiac Surgical Procedures/adverse effects Retrospective Studies Delirium/etiology Postoperative Complications/prevention & control Heart Rate/drug effects Hypnotics and Sedatives/administration & dosage/adverse effects Aged, 80 and over Incidence Dose-Response Relationship, Drug Hemodynamics/drug effects Middle Aged Cardiac surgery dexmedetomidine hemodynamics older adult postoperative delirium propofol |
| Comparative effectiveness of delirium recognition with and without a clinical decision assessment system on outcomes of hospitalized older adults: Cluster randomized controlled trial | Wang, J. Wu, Y. Huang, Y. Yang, F. | Int J Nurs Stud | 2024 |
Clinical decision support system, Clinical outcome, Delirium, Older adult |
| Risk factors of delirium after cardiac surgery: a systematic review and meta-analysis | Wang, Y. Wang, B. | J Cardiothorac Surg | 2024 |
Humans, Risk Factors, *Cardiac Surgical Procedures/adverse effects, *Delirium/etiology/epidemiology, *Postoperative, Complications/epidemiology, Cardiac surgery, Delirium, Meta-analysis |
| The role of psychotropics on the associations between extreme temperature and heat-related outcomes among people with mental health conditions: population-based study | Wong, A. Y. S. Iwagami, M. Taniguchi, Y. Kawamura, C. Suzuki, A. Douglas, I. J. Bhaskaran, K. Sugiyama, T. Kuroda, N. Nitsch, D. Tamiya, N. | Psychol Med | 2024 |
antidepressants, antipsychotics, delirium, heat-related illness, heatwave, myocardial, infarction |
| Longitudinal Trends in the Incidence of Hyperactive Delirium and Its Causes of Change After Surgery for Degenerative Lumbar Disease: A Population-Based Study of 7250 Surgical Patients Over 11 Years | Xie, B. L. Nie, L. Z. Zhong, B. Xiong, J. Nie, M. Ai, Q. X. Yang, D. | Orthop Surg | 2024 |
lumbar degenerative disease, postoperative analgesia, postoperative delirium, risk factors, trend of incidence rate |
| High level of systemic immune inflammation index elevates delirium risk among patients in intensive care unit | Xu, F. Zhang, S. Zhang, Y. | Sci Rep | 2024 |
Humans, *Delirium/epidemiology, Male, Female, *Intensive Care Units, Middle Aged, Aged, *Inflammation, Risk Factors, ROC Curve, Propensity Score, Delirium Intensive care unit, Medical information mart for intensive care-IV, Systemic immune-inflammation index |
| Optimization of the cardiac delirium index by including age, decrease in butyrylcholinesterase actitivity, preoperative HbA1c, and postoperative hemoglobin levels: results of a secondary analysis of a prospective observational study | Zajonz, T. S. Edinger, F. Markmann, M. Gräb, K. Sander, M. Kunzemann, C. Koch, C. Schneck, E. | Front Cardiovasc Med | 2024 |
biomarker, cardiac artery bypass graft surgery, cardiac surgery, cholinergic system, postoperative delirium |
| Overtime work of anesthesiologists is associated with increased delirium in older patients admitted to intensive care unit after noncardiac surgery: a secondary analysis | Zhao, Y. Chen, N. P. Su, X. Ma, J. H. Wang, D. X. | BMC Anesthesiol | 2024 |
Humans, Female, Male, Aged, *Intensive Care Units, *Anesthesiologists, *Postoperative Complications/epidemiology, *Delirium/epidemiology/etiology, Workload, Aged, 80 and over, Aging, Anesthesiologists, Delirium, Intensive Care Units, Operative, Postoperative Period, Surgical Procedures |
| Efficacy of repetitive transcranial magnetic stimulation in preventing postoperative delirium in elderly patients undergoing major abdominal surgery: A randomized controlled trial | Zhou, C. Gao, Y. N. Qiao, Q. Yang, Z. Zhou, W. W. Ding, J. J. Xu, X. G. Qin, Y. B. Zhong, C. C. | Brain Stimul | 2024 |
Bdnf, NfL, Postoperative delirium, rTMS |
| Effects of head direction during prone position on postoperative delirium in elderly patients undergoing thoracolumbar spine surgery: a study protocol for a randomised controlled trial | Zhu, J. Chen, Y. Chen, Y. Ma, H. Liu, F. Chen, Q. Wang, F. Chen, X. Xue, Z. Ni, K. Li, F. Qian, B. | BMJ Open | 2024 |
Humans, Prone Position, Aged Single-Blind Method, *Patient Positioning/methods, *Delirium/etiology/prevention & control, *Thoracic Vertebrae/surgery, Postoperative Complications, Randomized Controlled Trials as Topic, Lumbar Vertebrae/surgery, Male, Female, Head/surgery, Clinical Trial, Delirium & cognitive disorders, Posture, Thoracic surgery |
| Novel applications of sleep pharmacology as delirium therapeutics | Oldham, M. A. Spira, A. P. Yurcheshen, M. Pigeon, W. R. Palanca, B. J. A. Lee, H. B. | Sleep Med Rev | 2024 |
Circadian medicine |
| Risk factors for delirium occurring after deep brain stimulation surgery in patients with Parkinson's disease | Ozluk, E. Ozturk, G. | Acta Neurochir (Wien) | 2024 |
Humans |
| Intraoperative Burst Suppression by Analysis of Raw Electroencephalogram Postoperative Delirium in Older Adults Undergoing Spine Surgery: A Retrospective Cohort Study | Pawar, N. Zhou, S. Duarte, K. Wise, A. García, P. S. Kreuzer, M. Barreto Chang, O. L. | J Neurosurg Anesthesiol | 2024 |
Postoperative delirium Older adults Age EEG Anesthesia Perioperative Anesthesia Neurocognitive Disorder Assessment – Geriatric (PANDA-G) |
| Correlation Between Reduced Daily Living Competence and the Risk of Postoperative Delirium in Orthopedics and Trauma Surgery | Rahm, L. K. Moellmann, H. L. Stenmanns, C. Schiffner, E. Windolf, J. Frohnhofen, H. Latz, D. | J Clin Med | 2024 |
activities of daily living (ADL) |
| Neuroimaging Markers of Brain Reserve and Associations with Delirium in Patients with Intracerebral Hemorrhage | Rex, N. B. Chuck, C. C. Dandapani, H. G. Zhou, H. Y. Yi, T. Y. Collins, S. A. Bai, H. X. Eloyan, A. Jones, R. N. Boxerman, J. L. Girard, T. D. Boukrina, O. Reznik, M. E. | Neurocrit Care | 2024 |
Delirium |
| Altered Mental Status in Cancer | Rhee, J. Y. Nakhate, V. Soares, C. Tentor, Z. Dietrich, J. | Semin Neurol | 2024 |
Humans |
| Distinct brain and neurocognitive transformations after bariatric surgery: a pilot study | Roy, B. Thedim, M. Liew, C. Kumar, R. Vacas, S. | Front Neurosci | 2024 |
bariatric surgery |
| ICU Delirium | Sakusic, A. Rabinstein, A. A. | Neurol Clin | 2024 |
Humans |
| Pain-Induced Delirium in Patient with Dementia: A Case Report and Narrative Review | Santoso, Jdca Yulianti, E. | J Pain Palliat Care Pharmacother | 2024 |
acute confusional state |
| Update on Perioperative Delirium | Schenning, K. J. Mahanna-Gabrielli, E. Deiner, S. G. | Clin Geriatr Med | 2024 |
Humans |
| Perioperative blood pressure variability as a risk factor for postoperative delirium in the patients receiving cardiac surgery | Shen, X. Tao, H. Chen, W. Sun, J. Jin, R. Zhang, W. Hong, L. Zhang, C. | BMC Anesthesiol | 2024 |
Humans |
| Relationship between intracranial pressure and neurocognitive function among older adults after radical resection of rectal cancer | Song, B. Li, L. P. Wang, X. L. Guo, Y. Li, J. | World J Gastrointest Surg | 2024 |
Cognitive function |
| Delirium after cardiac arrest: incidence, risk factors, and association with neurologic outcome-insights from the Freiburg Delirium Registry | Staudacher, D. L. Heine, L. Maier, A. Kaier, K. Heidenreich, A. Rilinger, J. Rottmann, F. A. Biever, P. M. Supady, A. Wengenmayer, T. Westermann, D. Jäckel, M. | Clin Res Cardiol | 2024 |
Cardiac arrest |
| Postoperative delirium in patients undergoing TAVI versus SAVR - A systematic review and meta-analysis | Stavridis, D. Runkel, A. Starvridou, A. Fischer, J. Fazzini, L. Kirov, H. Wacker, M. Wippermann, J. Doenst, T. Caldonazo, T. | Int J Cardiol Heart Vasc | 2024 |
Meta-analysis |
| National outcomes for dementia patients undergoing cardiac surgery in a pre-structural era | Tang, A. Eitan, T. Dewan, K. C. Zhou, G. Rosinski, B. F. Koroukian, S. M. Svensson, L. G. Gillinov, A. M. Soltesz, E. G. | J Cardiothorac Surg | 2024 |
Humans |
| Cerebral Overperfusion Despite Reduced Cortical Metabolism Is Associated with Postoperative Delirium in Cardiac Surgery Patients: A Prospective Observational Study | Thudium, M. Braun, L. Stroemer, A. Mayr, A. Menzenbach, J. Saller, T. Soehle, M. Kornilov, E. Hilbert, T. | J Clin Med | 2024 |
bispectral index |
| Clear Minds: Unravelling Delirium in Older Adults | Tumbali, Y. Inventor, B. R. Paun, O. | J Psychosoc Nurs Ment Health Serv | 2024 |
Humans |
| Preoperative Neurofilament Light Associated With Postoperative Delirium in Hip Fracture Repair Patients Without Dementia | Umoh, M. E. Yan, H. Leoutsakos, J. M. Lewis, A. Marcantonio, E. R. Lyketsos, C. G. Inouye, S. K. Moghekar, A. Neufeld, K. J. Rosenberg, P. B. Sieber, F. Oh, E. S. | J Acad Consult Liaison Psychiatry | 2024 |
biomarker |
| Study on the predictive model of delirium risk after surgery for elderly hip fractures based on meta-analysis | Wan, W. Li, L. Zou, Z. Chen, W. | Eur Geriatr Med | 2024 |
Elderly hip fracture |