Delirium Bibliography

The searchable delirium bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons.  The NIDUS team keeps it updated for you on a monthly basis!  Feel free to search by author, title, year, keywords. It is primarily intended for clinicians and researchers interested in exploring these topics.

To retrieve full information, click on the title of the article and scroll down to read the abstract, journal, etc.

Each article is indexed by keywords taken from MEDLINE and other relevant databases.

You may base your search on as many search terms as you like. A search term can be a keyword, an author’s name, all or part of an article’s title, or the year of publication.

Search:
Total Records Found: 3342, showing 100 per page
TitleAuthorsJournalYearKeywords
Rapid in-person cognitive screening in the preoperative setting: Test considerations and recommendations from the Society for Perioperative Assessment and Quality Improvement (SPAQI) Arias, F. Wiggins, M. Urman, R. D. Armstrong, R. Pfeifer, K. Bader, A. M. Libon, D. J. Chopra, A. Price, C. C. Journal of Clinical Anesthesia 2020

anesthesiology
attention
clock drawing test
cognition
cognitive defect
dementia
geriatrics
human
language
memory
methodology
Mini Mental State Examination
neuropsychology
peer review
perioperative monitoring
primary medical care
priority journal
psychometry
review
sensitivity and specificity
telephone interview
total quality management
workflow

Updated nomenclature of delirium and acute encephalopathy: statement of ten Societies Slooter, A. J. C. Otte, W. M. Devlin, J. W. Arora, R. C. Bleck, T. P. Claassen, J. Duprey, M. S. Ely, E. W. Kaplan, P. W. Latronico, N. Morandi, A. Neufeld, K. J. Sharshar, T. MacLullich, A. M. J. Stevens, R. D. Intensive Care Medicine 2020

acute brain disease
article
delirium
human
nomenclature
organization

Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients Olsen, H. T. Nedergaard, H. K. Strøm, T. Oxlund, J. Wian, K. A. Ytrebø, L. M. Kroken, B. A. Chew, M. Korkmaz, S. Lauridsen, J. T. Toft, P. The New England journal of medicine 2020

NCT01967680
acute kidney failure
adult
agitation
APACHE
article
artificial ventilation
coma
controlled study
critically ill patient
delirium
female
human
intensive care unit
major clinical study
male
medical research
mortality
multicenter study
outcome assessment
randomization
randomized controlled trial
sedation
thromboembolism
ventilated patient

Ketamine Safety and Use in the Emergency Department for Pain and Agitation/Delirium: A Health System Experience Mo, H. Campbell, M. J. Fertel, B. S. Lam, S. W. Wells, E. J. Casserly, E. Meldon, S. W. The western journal of emergency medicine 2020

adult
adverse drug reaction
agitation
analgesia
article
clinical evaluation
comorbidity
delirium
dissociation
drug safety
drug therapy
emergency ward
endotracheal intubation
female
human
incidence
major clinical study
male
medical record review
nasal cannula
non rebreathing valve
patient information
pharmacokinetics
retrospective study
sedation
side effect
ketamine

Impact of skeletal muscle mass on postoperative delirium in patients undergoing free flap repair after oral cancer resection Makiguchi, T. Yamaguchi, T. Nakamura, H. Ogawa, M. Harimoto, N. Shirabe, K. Yokoo, S. Journal of plastic surgery and hand surgery 2020

adult
article
cancer patient
cancer surgery
controlled study
diet therapy
exercise
female
free tissue graft
human
insomnia
major clinical study
male
mouth cancer
muscle mass
positron emission tomography-computed tomography
postoperative delirium
preoperative evaluation
prevention
risk assessment
risk factor
sarcopenia
skeletal muscle
surgery
third lumbar vertebra
albumin
endogenous compound

Identifying delirium in Parkinson disease: A pilot study Lawson, R. A. Richardson, S. J. Yarnall, A. J. Burn, D. J. Allan, L. M. International Journal of Geriatric Psychiatry 2020

aged
article
clinical article
consensus
controlled study
delirium
DSM-5
female
frailty
hospital patient
hospitalization
human
incidence
male
Parkinson disease
pilot study
prevalence
vignette

Presurgical cognitive impairment is associated with postoperative delirium and postoperative cognitive dysfunction Knaak, C. Brockhaus, W. R. Spies, C. Borchers, F. Piper, S. K. Radtke, F. M. Lachmann, G. Minerva anestesiologica 2020

aged
anesthesia
article
controlled study
Diagnostic and Statistical Manual of Mental Disorders
female
follow up
human
major clinical study
male
postoperative cognitive dysfunction
postoperative delirium
randomization
randomized controlled trial

The effects of elective aortic repair, colorectal cancer surgery and subsequent postoperative delirium on long-term quality of life, cognitive functioning and depressive symptoms in older patients Janssen, T. L. de Vries, J. Lodder, P. Faes, M. C. Ho, G. H. Gobardhan, P. D. van der Laan, L. Aging & mental health 2020

abdominal aortic aneurysm
abdominal surgery
adult
aortic reconstruction
article
cancer patient
cancer surgery
cognition
cohort analysis
colorectal cancer
controlled study
depression
elective surgery
female
human
major clinical study
male
Mini Mental State Examination
outcome assessment
postoperative delirium
postoperative period
prospective study
psychological well-being
quality of life
questionnaire
risk factor
surgery
surgical patient
World Health Organization

American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Postoperative Delirium Prevention Hughes, C. G. Boncyk, C. S. Culley, D. J. Fleisher, L. A. Leung, J. M. McDonagh, D. L. Gan, T. J. McEvoy, M. D. Miller, T. E. Anesthesia and analgesia 2020

adult
adverse outcome
article
cognitive defect
complication
Delphi study
high risk population
hospital readmission
human
institutionalization
length of stay
major surgery
outcome assessment
physician
postoperative delirium
prevention
skill

Healthcare professionals' reports of cancer pain cues among older people with delirium: a qualitative-quantitative content analysis Graham, C. A. Chaves, G. Harrison, R. Gauthier, L. R. Nissim, R. Zimmermann, C. Chan, V. Rodin, G. Stevens, B. Gagliese, L. Journal of pain and symptom management 2020

adult
article
bivariate analysis
cancer pain
content analysis
controlled study
data analysis software
delirium
demography
doctor nurse relation
female
genetic transcription
human
informed consent
interview
major clinical study
male
pain assessment
quantitative analysis
self report

Preoperative Cognitive Abnormality, Intraoperative Electroencephalogram Suppression, and Postoperative Delirium: A Mediation Analysis Fritz, B. A. King, C. R. Ben Abdallah, A. Lin, N. Mickle, A. M. Budelier, T. P. Oberhaus, J. Park, D. Maybrier, H. R. Wildes, T. S. Avidan, M. S. Apakama, G. Aranake-Chrisinger, A. Bolzenius, J. Burton, J. Cui, V. Emmert, D. A. Goswami, S. Graetz, T. J. G Anesthesiology 2020

adult
aging
article
complication
convalescence
effect size
electroencephalogram
electroencephalography
female
general anesthesia
human
incidence
interview
major clinical study
male
medical record review
mentally disabled person
postoperative delirium
preoperative evaluation
randomization
randomized controlled trial
secondary analysis
surgery
university hospital

Delirium screening and mortality in patients with dementia admitted to acute hospitals Codling, D. Hood, C. Bassett, P. Smithard, D. Crawford, M. J. Aging & mental health 2020

aged
article
cognitive defect
controlled study
England
female
human
major clinical study
male
mortality
multicenter study
secondary analysis
very elderly
Wales

Do Neuroleptics Still Have a Role in Patients With Delirium? Nikooie, R. Oh, E. S. Zhang, A. Robinson, K. A. Needham, D. M. Annals of internal medicine 2020

adult
article
delirium
human
neuroleptic agent

Randomized clinical trial of intraoperative dexmedetomidine to prevent delirium in the elderly undergoing major non-cardiac surgery Li, C. J. Wang, B. J. Mu, D. L. Hu, J. Guo, C. Li, X. Y. Ma, D. Wang, D. X. British Journal of Surgery 2020

ChiCTRIPR15007654
injection device
Slgo
cisatracurium
dexamethasone
dexmedetomidine
flurbiprofen axetil
methylprednisolone
midazolam
morphine
parecoxib
propofol
sufentanil
adult
aged
all cause mortality
article
Barthel index
bradycardia
Child Pugh score
confusion assessment method
controlled study
delirium
double blind procedure
drug infusion
drug safety
extubation
female
follow up
human
hypertension
hypotension
incidence
loading drug dose
major clinical study
male
mental disease assessment
middle aged
Mini Mental State Examination
nausea and vomiting
numeric rating scale
observational study
perioperative period
priority journal
randomized controlled trial
risk factor

Risk factors for adverse drug reactions in older inpatients of geriatric wards at admission: Multicenter study Kojima, T. Matsui, T. Suzuki, Y. Takeya, Y. Tomita, N. Kozaki, K. Kuzuya, M. Rakugi, H. Arai, H. Akishita, M. Geriatrics and Gerontology International 2020

albumin
creatinine
adverse drug reaction
aged
albumin blood level
article
bleeding
cohort analysis
creatinine blood level
dehydration
delirium
disease association
dizziness
edema
electrolyte disturbance
endocrine disease
female
functional status
gastrointestinal disease
geriatric assessment
geriatric hospital
heart arrhythmia
heart failure
hematologic disease
hospital admission
human
hyperglycemia
hypoglycemia
Japan
kidney failure
length of stay
liver disease
major clinical study
male
medical record
multicenter study
neurologic disease
observational study
priority journal
rash
respiratory failure
retrospective study
risk assessment
risk factor
sedation
symptom
very elderly

Real-world effectiveness of ramelteon and suvorexant for delirium prevention in 948 patients with delirium risk factors Hatta, K. Kishi, Y. Wada, K. Takeuchi, T. Hashimoto, N. Suda, K. Taira, T. Tsuchida, K. Ohmori, T. Akizuki, N. Nishio, Y. Nakanishi, Y. Usui, C. Kurata, A. Horikawa, N. Eguchi, H. Ito, S. Muto, H. Nakamura, H. Uchimura, N. Journal of Clinical Psychiatry 2020

corticosteroid derivative
opiate derivative
ramelteon
suvorexant
acute disease
aged
article
clinical outcome
clinical practice
consultation
delirium
drug effect
drug efficacy
DSM-5
elective surgery
female
hospitalization
human
incidence
insomnia
major clinical study
male
mental health service
multicenter study
observational study
outcome assessment
patient decision making
physiatrist
prescription
priority journal
prospective study
risk assessment
risk factor
somnolence

Independent Association Between Type of Intraoperative Blood Transfusion and Postoperative Delirium After Complex Spinal Fusion for Adult Deformity Correction Elsamadicy, A. A. Adil, S. M. Charalambous, L. Drysdale, N. Koo, A. B. Lee, M. Kundishora, A. J. Camara-Quintana, J. Kolb, L. Laurans, M. Abbed, K. Karikari, I. O. Spine 2020

adult
age
article
bleeding
blood transfusion
cohort analysis
comorbidity
complication
controlled study
female
health care cost
hospitalization
human
incidence
major clinical study
male
medical record
outcome assessment
patient care
postoperative delirium
retrospective study
spine fusion
spine malformation
surgery

Practices related to assessment of sedation, analgesia and delirium among critical care pediatricians in Brazil Colleti Junior, J. Araujo, O. R. Andrade, A. B. Carvalho, W. B. Einstein (Sao Paulo, Brazil) 2020

analgesia
article
Brazil
child
delirium
demography
e-mail
human
patient comfort
pediatric intensive care unit
pediatrician
questionnaire
Ramsay Sedation Scale
sedation

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Chen, N. Zhou, M. Dong, X. Qu, J. Gong, F. Han, Y. Qiu, Y. Wang, J. Liu, Y. Wei, Y. Xia, J. Yu, T. Zhang, X. Zhang, L. The Lancet 2020

adult
age
article
China
chronic disease
clinical feature
confusion
Coronavirus disease 2019
Coronavirus infection
coughing
descriptive research
disease exacerbation
dyspnea
epidemiological data
exposure
female
fever
follow up
headache
human
major clinical study
male
marketing
medical history
multiple organ failure
myalgia
nausea and vomiting
pneumothorax
priority journal
real time polymerase chain reaction
respiratory distress
retrospective study
sea food
sore throat
thorax pain
virus detection
virus pneumonia

Association between postoperative delirium and mortality in elderly patients undergoing hip fractures surgery: a meta-analysis Bai, J. Liang, Y. Zhang, P. Liang, X. He, J. Wang, J. Wang, Y. Osteoporosis International 2020

article
disease association
DSM-III
DSM-IV
follow up
hip fracture
hip surgery
hospital mortality
human
incidence
perioperative period
postoperative delirium
postoperative period
prevalence
priority journal
scoring system
surgical mortality
surgical risk
systematic review

Impact of frailty on short-term outcomes in patients undergoing transsphenoidal pituitary surgery Asemota, A. O. Gallia, G. L. Journal of Neurosurgery 2020

acute heart infarction
acute kidney failure
adult
aged
article
Black person
brain hematoma
brain hemorrhage
brain infarction
cerebrospinal fluid rhinorrhea
Charlson Comorbidity Index
cohort analysis
comorbidity
consciousness disorder
deep vein thrombosis
delirium
diabetes insipidus
diplopia
epistaxis
female
frailty
Hispanic
human
hypernatremia
hyperosmolality
hypertension
hyponatremia
hypoosmolality
hypophysis tumor
iatrogenic disease
inappropriate vasopressin secretion
length of stay
lowest income group
lung embolism
lung insufficiency
major clinical study
male
medicaid
medicare
meningitis
mental health
middle aged
mortality rate
ophthalmoplegia
postoperative nausea and vomiting
priority journal
reoperation
strabismus
transsphenoidal hypophysectomy
treatment outcome
visual field defect

Randomised controlled trial to investigate the relationship between mild hypercapnia and cerebral oxygen saturation in patients undergoing major surgery Wong, C. Churilov, L. Cowie, D. Tan, C. O. Hu, R. Tremewen, D. Pearce, B. Pillai, P. Karalapillai, D. Bellomo, R. Weinberg, L. BMJ Open 2020

delirium
hypercapnia
oximetry
respiration, artificial
spectroscopy, near infrared

Establishment and validation of a delirium prediction model for neurosurgery patients in intensive care Wang, J. Ji, Y. Wang, N. Chen, W. Bao, Y. Qin, Q. Ma, C. Xiao, Q. Li, S. Int J Nurs Pract 2020

delirium
neurosurgery
nursing
prediction model
risk factors

Early mobilisation after transfemoral transcatheter aortic valve implantation: results of the MobiTAVI trial Vendrik, J. Vlastra, W. van Mourik, M. S. Delewi, R. Beijk, M. A. Lemkes, J. Wykrzykowska, J. J. de Winter, R. J. Henriques, J. S. Piek, J. J. Vis, M. M. Koch, K. T. Baan, J., Jr. Neth Heart J 2020

Ambulation
Early mobilisation
Percutaneous valve
Safety protocol
Transfemoral transcatheter aortic valve implantation
Vascular complications

Influence of sedation on delirium recognition in critically ill patients: A multinational cohort study van den Boogaard, M. Wassenaar, A. van Haren, F. M. P. Slooter, A. J. C. Jorens, P. G. van der Jagt, M. Simons, K. S. Egerod, I. Burry, L. D. Beishuizen, A. Pickkers, P. Devlin, J. W. Aust Crit Care 2020

Assessment
Cam-icu
Delirium
Icdsc
Intensive care
Sedation
NCT02518646
adult
article
checklist
clinical evaluation
cohort analysis
controlled study
critically ill patient
female
human
intensive care psychosis
intensive care unit
major clinical study
male
multicenter study
nurse
prospective study
Richmond Agitation Sedation Scale
secondary analysis

Intraoperative reduction of vasopressors using processed electroencephalographic monitoring in patients undergoing elective cardiac surgery: a randomized clinical trial Sponholz, C. Schuwirth, C. Koenig, L. Hoyer, H. Coldewey, S. M. Schelenz, C. Doenst, T. Kortgen, A. Bauer, M. J Clin Monit Comput 2020

Adverse events
Cardiac anesthesia
Catecholamines
Neuromonitoring

Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery Smith, T. O. Gilbert, A. W. Sreekanta, A. Sahota, O. Griffin, X. L. Cross, J. L. Fox, C. Lamb, S. E. Cochrane Database Syst Rev 2020
Prospective Evaluation of Delirium in Geriatric Patients Undergoing Emergency General Surgery Saljuqi, A. T. Hanna, K. Asmar, S. Tang, A. Zeeshan, M. Gries, L. Ditillo, M. Kulvatunyou, N. Castanon, L. Joseph, B. J Am Coll Surg 2020
Predisposing and Precipitating Factors Associated With Postoperative Delirium in Patients Undergoing Cardiac Surgery at a Veterans Affairs Medical Center: A Pilot Retrospective Analysis Russell, M. D. Pinkerton, C. Sherman, K. A. Ebert, T. J. Pagel, P. S. J Cardiothorac Vasc Anesth 2020

Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition
cardiac surgery complications
cardiopulmonary bypass
delirium
geriatrics

Dopaminergic Hyperactivity in Neurological Patients with Delirium Ramirez-Bermudez, J. Perez-Neri, I. Montes, S. Nente, F. Ramirez-Abascal, M. Carrillo-Mezo, R. Perez-Esparza, R. Soto-Hernandez, J. L. Espinola-Nadurille, M. Bayliss, L. De Jesus Flores Rivera, J. Rios, C. Arch Med Res 2020

Autoimmune limbic encephalitis
Confusional state
Delirium
Dopamine
Homovanillic acid
Neuropsychiatry

Effects of intravenous and mask induction on post-operative emergence delirium in pediatric patients undergoing tonsillectomy with or without adenoidectomy Peker, K. Polat, R. Ir J Med Sci 2020

Intravenous induction
Mask induction
Pediatric emergence delirium
adenoidectomy
anesthesia induction
article
cannula
child
controlled study
emergence agitation
female
human
incidence
leg
major clinical study
male
operating room
pediatric anesthesia
pediatric patient
postoperative pain
preschool child
prospective study
randomized controlled trial
recovery room
remission
single blind procedure
surgery
tonsillectomy
university hospital
vascular access
nitrous oxide
oxygen
sevoflurane

Safety and Tolerability of Rapid Administration Undiluted Levetiracetam Morgan, O. Medenwald, B. Neurocrit Care 2020

Anticonvulsants
Humans
Intravenous

New use of psychotropic medication after hospitalization among people with dementia Mollers, T. Perna, L. Stocker, H. Ihle, P. Schubert, I. Schottker, B. Frolich, L. Brenner, H. Int J Geriatr Psychiatry 2020

claims data
dementia
hospitalization
psychotropic medication

A logistic regression analysis comparing minimalistic approach and intubation anaesthesia in patients undergoing transfemoral transcatheter aortic valve replacement Maier, A. Hammerich, B. Humburger, F. Brieschal, T. Heidt, T. Bothe, W. Schrofel, H. Kaier, K. Zehender, M. Reinohl, J. Bode, C. von Zur Muhlen, C. Stachon, P. PLoS One 2020
Anticipating Postoperative Delirium During Burst Suppression Using Electroencephalography Ma, O. Crepeau, A. Z. Dutta, A. Bliss, D. IEEE Trans Biomed Eng 2020

adult
article
brain injury
clinical article
complication
cooling
electroencephalography
female
heart arrest
heart surgery
human
hypothermia
incidence
male
postoperative delirium
prognosis
reperfusion
surgery
surgical technique
warming

Can haloperidol prophylaxis reduce the incidence of delirium in critically ill patients in intensive care units? A systematic review and meta-analysis Lin, P. Zhang, J. Shi, F. Liang, Z. A. Heart Lung 2020

Delirium
Haloperidol
Intensive care
Meta-analysis
Randomized clinical trial

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit Li, Y. Ma, J. Jin, Y. Li, N. Zheng, R. Mu, W. Wang, J. Si, J. H. Chen, J. Shang, H. C. Cochrane Database Syst Rev 2020
Delirium prevalence and prevention in patients with acute brain injury: A prospective before-and-after intervention study Larsen, L. K. Moller, K. Petersen, M. Egerod, I. Intensive Crit Care Nurs 2020

Brain injuries
Critical care
Critical care nursing
Delirium
Intensive care units
Neuroscience nursing
Prevention

Postoperative anaemia might be a risk factor for postoperative delirium and prolonged hospital stay: A secondary analysis of a prospective cohort study Kunz, J. V. Spies, C. D. Bichmann, A. Sieg, M. Mueller, A. PLoS One 2020
Development of a Simple and Practical Delirium Screening Tool for Use in Surgical Wards Kubota, K. Suzuki, A. Ohde, S. Yamada, U. Fujitani, I. Koitabashi, A. J Nurs Res 2020

adult
area under the curve
article
bootstrapping
controlled study
delirium
diagnostic accuracy
diagnostic test accuracy study
disorientation
female
hallucination
hospital patient
human
major clinical study
male
medical record
nurse
receiver operating characteristic
restlessness
retrospective study
sensitivity and specificity
somnolence
surgical ward

Psychometric evaluation of the family caregiver ICU delirium knowledge questionnaire Krewulak, K. D. Bull, M. J. Ely, E. W. Stelfox, H. T. Fiest, K. M. BMC Health Serv Res 2020

Critical care
Delirium prevention and management
Family caregivers
Intensive care unit
adult
article
caregiver
content validity
controlled study
critically ill patient
Cronbach alpha coefficient
cross-sectional study
delirium
face validity
female
human
intensive care unit
internal consistency
major clinical study
male
multidisciplinary team
nurse
path analysis
questionnaire
risk factor

The Impact of Acute Kidney Injury in the Perioperative Period on the Incidence of Postoperative Delirium in Patients Undergoing Coronary Artery Bypass Grafting-Observational Cohort Study Kotfis, K. Slozowska, J. Listewnik, M. Szylinska, A. Rotter, I. Int J Environ Res Public Health 2020

Aki
Cabg
Gfr
Kdigo
Pod
acute kidney injury
creatinine
delirium
glomerular filtration rate

Delirium point prevalence studies in inpatient settings: A systematic review and meta-analysis Koirala, B. Hansen, B. R. Hosie, A. Budhathoki, C. Seal, S. Beaman, A. Davidson, P. M. J Clin Nurs 2020

delirium
inpatient
meta-analysis
point prevalence
systematic review
adult
benchmarking
dementia
female
high risk patient
hospital patient
human
male
patient care
prevalence
quality improvement study
review
risk assessment
sample siz

Validity and Reliability of the Memorial Delirium Assessment Scale-Thai Version (MDAS-T) for Assessment of Delirium in Palliative Care Patients Klankluang, W. Pukrittayakamee, P. Atsariyasing, W. Siriussawakul, A. Chanthong, P. Tongsai, S. Tayjasanant, S. Oncologist 2020

Delirium
Mdas
Palliative care
Screening
Sensitivity and specificity
Validity and reliability
adult
article
construct validity
content validity
controlled study
correlation coefficient
Cronbach alpha coefficient
distress syndrome
DSM-5
exploratory factor analysis
female
gold standard
human
intensive care unit
internal consistency
interrater reliability
major clinical study
male
palliative therapy
principal component analysis
receiver operating characteristic
sensitivity and specificity

The Impact of an Attending Intensivist on the Clinical Outcomes of Patients Admitted to the Cardiac Surgical Intensive Care Unit after Coronary Artery Bypass Grafting Kim, D. J. Sohn, B. Kim, H. Chang, H. W. Lee, J. H. Kim, J. S. Lim, C. Park, K. H. Korean J Thorac Cardiovasc Surg 2020

Coronary artery bypass grafting
Critical care
Intensive care unit staffing
Intensivist
Postoperative complications

Working Collaboratively: Outcomes of Geriatrician Input in Older Patients Undergoing Emergency Laparotomy in a District General Hospital Khan, K. A. Subramanian, T. Richters, M. Mubarik, A. Saad Abdalla Al-Zawi, A. Thorn, C. C. Chalstrey, S. Gunasekera, S. Cureus 2020

ageing & frailty
cepod
cognitive impairment
elderly patients
emergency laparotomy
geriatric surgical liaison
length of stay
perioperative care

Postoperative delirium: the findings from a multidisciplinary survey Jin, Z. Rahman, A. Pattnaik, S. Smith, M. Psychogeriatrics 2020

education
hypoactive delirium
management
postoperative delirium
screening
acute psychosis
adult
article
complication
diagnostic error
education
human
mortality risk
multidisciplinary team
postoperative delirium
prognosis
surgery

Postoperative delirium after reconstructive surgery for oral tumor: a retrospective clinical study Ishibashi-Kanno, N. Takaoka, S. Nagai, H. Okubo-Sato, M. Fukuzawa, S. Uchida, F. Yamagata, K. Yanagawa, T. Bukawa, H. Int J Oral Maxillofac Surg 2020

Delirium
Oral tumor
Postoperative delirium
Reconstructive surgery

Joining Forces against Delirium - From Organ-System Care to Whole-Human Care Inouye, S. K. N Engl J Med 2020

Aged
Clinical Protocols
Coronary Artery Bypass/adverse effects
Delirium/diagnosis/etiology/ prevention & control
Diagnostic Errors
Humans
Iatrogenic Disease/ prevention & control
Male
Cinical practice
Evidence based practice
Frailty
Geriatric care
Health care cost
Health care delivery
Health care policy
Health care system
Health program
Hospital mortality
Human
Medicare
Priority journal
Reimbursement
Review
Vulnerable population

Incidence of and risk factors for postoperative delirium in older adult patients undergoing noncardiac surgery: a prospective study Iamaroon, A. Wongviriyawong, T. Sura-Arunsumrit, P. Wiwatnodom, N. Rewuri, N. Chaiwat, O. BMC Geriatr 2020

Collaborative approach
Incidence
Noncardiac surgery
Older adult patients
Postoperative delirium
Risk factors
aged
anesthesiologist
article
Barthel index
cognitive defect
complication
controlled study
DSM-5
female
geriatrician
hematocrit
high risk population
hospitalization
human
incidence
major clinical study
male
multidisciplinary team
perioperative period
peroperative complication
postoperative delirium
preoperative evaluation
prospective study
questionnaire
risk factor
surgery
univariate analysis
benzodiazepine
opiate

Delirium misdiagnosis risk in psychiatry: a machine learning-logistic regression predictive algorithm Hercus, C. Hudaib, A. R. BMC Health Serv Res 2020

Delirium
Input variables
Machine learning-logistic classifier
Misdiagnosis

Patterns of Potentially Inappropriate Bladder Antimuscarinic Use in People with Dementia: A Retrospective Cohort Study Green, A. R. Segal, J. Boyd, C. M. Huang, J. Roth, D. L. Drugs Real World Outcomes 2020
Incidence, determinants and consequences of delirium in older patients after transcatheter aortic valve implantation Goudzwaard, J. A. de Ronde-Tillmans, Mjag de Jager, T. A. J. Lenzen, M. J. Nuis, R. J. van Mieghem, N. M. Daemen, J. de Jaegere, P. P. T. Mattace-Raso, F. U. S. Age Ageing 2020

aortic stenosis
mortality
post-operative delirium
transcatheter aortic valve implantation

Neuromonitoring of delirium with quantitative pupillometry in sedated mechanically ventilated critically ill patients Favre, E. Bernini, A. Morelli, P. Pasquier, J. Miroz, J. P. Abed-Maillard, S. Ben-Hamouda, N. Oddo, M. Crit Care 2020

Cholinergic
Delirium
Mechanical ventilation
Pupillary reactivity
Pupillometry

Cognitive Outcomes of Long-term Benzodiazepine and Related Drug (BDZR) Use in People Living With Mild to Moderate Alzheimer's Disease: Results From NILVAD Dyer, A. H. Murphy, C. Lawlor, B. Kennelly, S. P. J Am Med Dir Assoc 2020

Dementia
Benzodiazepines
Benzodiazepines and related drugs
Cognition

'Nonagenarians' with a hip fracture: is a different orthogeriatric treatment strategy necessary? de Groot, R. Nijmeijer, W. S. Folbert, E. C. Vollenbroek-Hutten, M. M. R. Hegeman, J. H. Arch Osteoporos 2020

Frail elderly
Hip fracture
Nonagenarians
Orthogeriatric
Surgery

Comparison of single minimum dose administration of dexmedetomidine and midazolam for prevention of emergence delirium in children: a randomized controlled trial Cho, E. A. Cha, Y. B. Shim, J. G. Ahn, J. H. Lee, S. H. Ryu, K. H. J Anesth 2020

Dexmedetomidine
Emergence agitation
Emergence delirium
Midazolam
Pediatric anesthesia

Innovative care models across settings: Providing nursing care to older adults Cacchione, P. Z. Geriatr Nurs 2020

Evercare/Optum
Interact
Niche
Pace
Transitional Care Model

Is the bispectral index monitoring protective against postoperative cognitive decline? A systematic review with meta-analysis Bocskai, T. Kovacs, M. Szakacs, Z. Gede, N. Hegyi, P. Varga, G. Pap, I. Toth, I. Revesz, P. Szanyi, I. Nemeth, A. Gerlinger, I. Karadi, K. Lujber, L. PLoS One 2020

Anesthesia
Metaanalysis
Anesthesiology monitoring
Surgical and invasive medical procedures
Elderly
General anesthesia
Randomized controlled trials
Cognitive impairment

Postanesthesia care unit delirium following robot-assisted vs open retropubic radical prostatectomy: A prospective observational study Beck, S. Hoop, D. Ragab, H. Rademacher, C. Messner-Schmitt, A. von Breunig, F. Haese, A. Graefen, M. Zollner, C. Fischer, M. Int J Med Robot 2020

Trendelenburg position
anesthesia
postoperative delirium
postoperative neurocognitive disorders
radical prostatectomy

The impact of Hospital Elder Life Program interventions, on 30-day readmission Rates of older hospitalized patients Zachary, W. Kirupananthan, A. Cotter, S. Barbara, G. H. Cooke, R. C., 3rd Sipho, M. Arch Gerontol Geriatr 2020

Cost savings
Delirium
Elderly
Geriatric
Older
Readmission

Prevalence and risk factors for postoperative delirium in patients with colorectal carcinoma: a systematic review and meta-analysis Yang, Z. Wang, X. F. Yang, L. F. Fang, C. Gu, X. K. Guo, H. W. Int J Colorectal Dis 2020

Coloretal cancer
Delirium
Meta-analysis
Prevalence
Risk factor

Incidence, risk factors, and outcomes for sepsis-associated delirium in patients with mechanical ventilation: A sub-analysis of a multicenter randomized controlled trial Yamamoto, T. Mizobata, Y. Kawazoe, Y. Miyamoto, K. Ohta, Y. Morimoto, T. Yamamura, H. Journal of Critical Care 2020

fentanyl
midazolam
adult
aged
article
artificial ventilation
clinical outcome
comparative study
controlled study
disease association
emergency surgery
extubation
female
hospitalization
human
incidence
independent variable
intensive care unit
intubation
length of stay
major clinical study
male
mortality
multicenter study
predictor variable
randomized controlled trial
retrospective study
risk factor
self concept
sepsis associated encephalopathy

Effects of different BP management strategies on postoperative delirium in elderly patients undergoing hip replacement: A single center randomized controlled trial Xu, X. Hu, X. Wu, Y. Li, Y. Zhang, Y. Zhang, M. Yang, Q. J Clin Anesth 2020

Blood pressure
Hip replacement
Postoperative delirium
Regional cerebral oxygen saturation
were involved in supporting this manuscript.

Preoperative prognostic nutritional index predicts postoperative delirium in elderly patients after hip fracture surgery Xing, H. Xiang, D. Li, Y. Ji, X. Xie, G. Psychogeriatrics 2020

elderly
hip fracture
postoperative delirium
prognostic nutritional index

The effects of early femoral nerve block intervention on preoperative pain management and incidence of postoperative delirium geriatric patients undergoing trochanteric femur fracture surgery: A randomized controlled trial Uysal, A. I. Altiparmak, B. Yasar, E. Turan, M. Canbek, U. Yilmaz, N. Gumus Demirbilek, S. Ulus Travma Acil Cerrahi Derg 2020
A smartphone-based test for the assessment of attention deficits in delirium: A case-control diagnostic test accuracy study in older hospitalised patients Tieges, Z. Stott, D. J. Shaw, R. Tang, E. Rutter, L. M. Nouzova, E. Duncan, N. Clarke, C. Weir, C. J. Assi, V. Ensor, H. Barnett, J. H. Evans, J. Green, S. Hendry, K. Thomson, M. McKeever, J. Middleton, D. G. Parks, S. Walsh, T. Weir, A. J. Wilson, E. Qua PLoS One 2020
A 'real-world' analysis of risk factors for post liver transplant delirium and the effect on length of stay Tavabie, O. D. Colwill, M. Adamson, R. McPhail, M. J. W. Bernal, W. Jassem, W. Prachialias, A. Heneghan, M. Aluvihare, V. R. Agarwal, K. Eur J Gastroenterol Hepatol 2020
Intraoperative hypotension and delirium in patients with hip fracture Tantardini, V. Roca, F. Bahri, O. Compere, V. Dujardin, F. Chassagne, P. Geriatr Psychol Neuropsychiatr Vieil 2020

anaesthesia
delirium
hip fracture
low blood pressure

Evaluation of emergence agitation after general anaesthesia in rhinoplasty patients: Inhalation anaesthesia versus total intravenous anaesthesia Talih, G. Yüksek, A. Şahin, E. American Journal of Otolaryngology - Head and Neck Medicine and Surgery 2020

adult
anesthesia induction
article
bleeding
controlled study
emergence agitation
female
gas flow
human
image quality
incidence
intravenous anesthesia
Likert scale
low flow anesthesia
lung alveolus
major clinical study
male
nausea and vomiting
nose reconstruction
prospective study
randomized controlled trial
Richmond Agitation Sedation Scale
satisfaction
surgeon
propofol
sevoflurane

Implementation of a multiprofessional, multicomponent delirium management guideline in two intensive care units, and its effect on patient outcomes and nurse workload: a pre-post design retrospective cohort study Schubert, M. Bettex, D. Steiger, P. Schurch, R. Haller, A. Bogdanovic, J. Garcia Nunez, D. Schwarz, U. Siegemund, M. Swiss Med Wkly 2020
Cerebrospinal Fluid Levels of Interleukin-8 in Delirium, Dementia, and Cognitively Healthy Patients Sajjad, M. U. Blennow, K. Knapskog, A. B. Idland, A. V. Chaudhry, F. A. Wyller, T. B. Zetterberg, H. Watne, L. O. J Alzheimers Dis 2020

Alzheimer’s disease
cytokines
delirium
depression

Prehospital Anticholinergic Burden Is Associated With Delirium but Not With Mortality in a Population of Acutely Ill Medical Patients Rigor, J. Rueff Rato, I. Ferreira, P. M. Pereira, R. Ribeiro, C. Teixeira, D. Mesquita Oliveira, P. Silva, A. M. Pereira, S. Costa, I. Ferreira, P. Sequeira, M. Monteiro-Soares, M. Martins-Mendes, D. J Am Med Dir Assoc 2020

Anticholinergic
delirium
geriatrics
mortality

Impact of Vitamin C and Thiamine Administration on Delirium-Free Days in Patients with Septic Shock Park, J. E. Shin, T. G. Jo, I. J. Jeon, K. Suh, G. Y. Park, M. Won, H. Chung, C. R. Hwang, S. Y. J Clin Med 2020

delirium
sepsis
septic shock
thiamine
vitamin C

Evaluation of an updated sedation protocol to reduce benzodiazepines in a pediatric intensive care unit Michel, J. Hofbeck, M. Peper, A. K. Kumpf, M. Neunhoeffer, F. Curr Med Res Opin 2020

Cardiac surgery
analgesia
congenital heart disease
nurse-driven protocol
pediatric delirium
withdrawal

A qualitative exploration of the views of patients and their relatives regarding interventions to minimize the distress related to postoperative delirium Meilak, C. Biswell, E. Willis, R. Partridge, J. Dhesi, J. Int J Geriatr Psychiatry 2020

aged
article
clinical article
communication skill
family stress
female
human
information seeking
male
patient counseling
patient education
postoperative delirium
qualitative research
relative
semi structured interview
staff training
thematic analysis
very elderly

Incidence and risk factors of postoperative delirium in elderly patients undergoing urological surgery: A multi-institutional prospective study Matsuki, M. Tanaka, T. Takahashi, A. Inoue, R. Hotta, H. Itoh, N. Taguchi, K. Kato, R. Kobayashi, K. Masumori, N. Int J Urol 2020

elderly patients
multicenter prospective cohort study
postoperative delirium
risk factors
urological surgery

Still Predicting Delirium After All These Years Marcantonio, ER Anesth Analg 2020
Ketamine sedation in mechanically ventilated patients: A systematic review and meta-analysis Manasco, A. T. Stephens, R. J. Yaeger, L. H. Roberts, B. W. Fuller, B. M. Journal of Critical Care 2020

fentanyl
hypertensive factor
ketamine
midazolam
propofol
agitation
article
artificial ventilation
delirium
drug infusion
human
hypertension
length of stay
meta analysis
mortality
randomized controlled trial (topic)
risk benefit analysis
side effect
systematic review
tachycardia

A Study of the Psychometric Properties of the “Stanford Proxy Test for Delirium” (S-PTD): A New Screening Tool for the Detection of Delirium Maldonado, J. R. Sher, Y. I. Benitez-Lopez, M. A. Savant, V. Garcia, R. Ament, A. De Guzman, E. Psychosomatics 2020

adult
article
controlled study
delirium
demography
diagnosis
diagnostic test accuracy study
early diagnosis
female
hospitalization
human
major clinical study
male
middle aged
nurse
psychiatrist
sensitivity and specificity

Risk factors for postoperative delirium after colorectal surgery: a systematic review and meta-analysis Lee, S. H. Lim, S. W. Int J Colorectal Dis 2020

Colorectal surgery
Postoperative delirium
Risk factor

Results from a double blinded, randomized, placebo-controlled, feasibility trial of melatonin for the treatment of delirium in older medical inpatients Lange, P. W. Clayton-Chubb, D. I. Watson, R. Maier, A. B. Intern Med J 2020

Delirium
Melatonin
Neurocognitive Disorders
Post-Operative Cognitive Decline
Sepsis-Associated Encephalopathy
Sleep
Treatment

Risk factors and outcomes among delirium subtypes in adult ICUs: A systematic review Krewulak, K. D. Stelfox, H. T. Ely, E. W. Fiest, K. M. J Crit Care 2020

Critical care
Delirium
Risk factors
Subtype
Systematic review
any conflicts of interest relevant to this manuscript.

Survey of analgesia and sedation in pediatric intensive care units in Japan Koizumi, T. Kurosawa, H. Pediatr Int 2020

analgesia
delirium
pediatric intensive care units
sedation
withdrawal syndrome

Association of neuronal repair biomarkers with delirium among survivors of critical illness Hayhurst, C. J. Patel, M. B. McNeil, J. B. Girard, T. D. Brummel, N. E. Thompson, J. L. Chandrasekhar, R. Ware, L. B. Pandharipande, P. P. Ely, E. W. Hughes, C. G. Journal of Critical Care 2020

NCT00392795
brain derived neurotrophic factor
interleukin 6
ubiquitin carboxyl terminal esterase L1
ubiquitin thiolesterase
unclassified drug
adult
aged
APACHE
article
Charlson Comorbidity Index
clinical trial
cohort analysis
controlled study
critically ill patient
delirium
disease duration
female
hospital admission
human
intensive care unit
major clinical study
male
observational study
pathophysiology
population research
prevalence
prospective study
protein blood level
respiratory failure
shock
survivor

Dexmedetomidine's Relationship to Delirium in Patients Undergoing Cardiac Surgery: A Systematic Review Halpin, E. Inch, H. O'Neill, M. Crit Care Nurs Q 2020
Management of delirium at an academic medical center: Plans for antipsychotic prescribing upon discharge Halavonich, L. Robert, S. McGraw, D. Weeda, E. Mullinax, K. Bass, B. Ment Health Clin 2020

antipsychotic
delirium
discharge
disclose.

Association Between Level of Arousal and 30-Day Survival in Acutely Ill Older Adults Garcez, F. B. Jacob-Filho, W. Avelino-Silva, T. J. J Am Med Dir Assoc 2020

Delirium
arousal
dementia
hospitalization
mortality

Drug therapy for delirium in terminally ill adults Finucane, A. M. Jones, L. Leurent, B. Sampson, E. L. Stone, P. Tookman, A. Candy, B. Cochrane Database Syst Rev 2020
Delirium in patients with hip fracture is associated with increased heart rate variability Ernst, G. Watne, L. O. Rostrup, M. Neerland, B. E. Aging Clin Exp Res 2020

Autonomic nervous system
Delirium
Heart rate variability
Hip fracture

Risk factors for delirium after esophagectomy Dezube, A. R. Bravo-Iniguez, C. E. Yelamanchili, N. De Leon, L. E. Tarascio, J. Jaklitsch, M. T. Wee, J. O. J Surg Oncol 2020

delirium
esophageal cancer
esophagectomy
perioperative factors
surgical outcomes
surgical technique

Delirium in a Tertiary PICU: Risk Factors and Outcomes Dervan, L. A. Di Gennaro, J. L. Farris, R. W. D. Watson, R. S. Pediatr Crit Care Med 2020
Validity and Reliability of the Brazilian Portuguese Version of the Pediatric Confusion Assessment Method for the ICU de Castro, R. E. V. Prata-Barbosa, A. de Magalhaes-Barbosa, M. C. Cunha, Ajlad Cheniaux, E. Smith, H. A. B. Pediatr Crit Care Med 2020
Outcomes for patients with delirium receiving hospital-in-the-home treatment: An Australian perspective Chia, J. Eeles, E. M. Tattam, K. Yerkovich, S. Australas J Ageing 2020

delirium
frail elderly
home care services
hospital-based

A software to prevent delirium in hospitalised older adults: development and feasibility assessment Alvarez, E. A. Garrido, M. Ponce, D. P. Pizarro, G. Cordova, A. A. Vera, F. Ruiz, R. Fernandez, R. Velasquez, J. D. Tobar, E. Salech, F. Age Ageing 2020

delirium
gerontechnology
non-pharmacological interventions
prevention
software

Cholinesterase alterations in delirium after cardiosurgery: a German monocentric prospective study Adam, E. H. Haas, V. Lindau, S. Zacharowski, K. Scheller, B. BMJ Open 2020

acetylcholinesterase
butyrylcholinesterase
cardiac surgery
cholinesterase
postoperative delirium

Cornell Assessment of Pediatric Delirium: a valid, rapid, observational tool for screening delirium in the PICU* Traube, C. Silver, G. Kearney, J. Patel, A. Atkinson, T. M. Yoon, M. J. Halpert, S. Augenstein, J. Sickles, L. E. Li, C. Greenwald, B. Crit Care Med 2014

Adolescent
Age Distribution
Child
Child, Preschool
Cohort Studies
Critical Care/methods
Delirium/*diagnosis/epidemiology
Diagnostic and Statistical Manual of Mental Disorders
Feasibility Studies
Female
Humans
Infant
Infant, Newborn
*Intensive Care Units, Pediatric
Male
Mass Screening/*methods
Prevalence
Psychometrics
Reproducibility of Results
Sensitivity and Specificity
Severity of Illness Index
Sex Distribution
Young Adult

The Preschool Confusion Assessment Method for the ICU: Valid and Reliable Delirium Monitoring for Critically Ill Infants and Children Smith, H. A. Gangopadhyay, M. Goben, C. M. Jacobowski, N. L. Chestnut, M. H. Savage, S. Rutherford, M. T. Denton, D. Thompson, J. L. Chandrasekhar, R. Acton, M. Newman, J. Noori, H. P. Terrell, M. K. Williams, S. R. Griffith, K. Cooper, T. J. Ely, E. W. F Crit Care Med 2016

Child, Preschool
Confusion/*diagnosis
*Critical Illness
Delirium/*diagnosis
Female
Humans
Infant
*Intensive Care Units, Pediatric
Male
*Neuropsychological Tests
Observer Variation
Prospective Studies
Reproducibility of Results
Respiration, Artificial
Sensitivity and Specificity
Severity of Illness Index

Diagnosing delirium in critically ill children: Validity and reliability of the Pediatric Confusion Assessment Method for the Intensive Care Unit Smith, H. A. Boyd, J. Fuchs, D. C. Melvin, K. Berry, P. Shintani, A. Eden, S. K. Terrell, M. K. Boswell, T. Wolfram, K. Sopfe, J. Barr, F. E. Pandharipande, P. P. Ely, E. W. Crit Care Med 2011

Child
Child, Preschool
Cohort Studies
Confusion/diagnosis
Critical Care/methods
*Critical Illness
Delirium/*diagnosis
Female
Humans
*Intensive Care Units, Pediatric
Male
Neuropsychiatry/standards
Observer Variation
Practice Guidelines as Topic
Prospective Studies
Psychometrics
Reference Standards
Reproducibility of Results
Risk Assessment
Sensitivity and Specificity
Severity of Illness Index

Development and psychometric evaluation of the pediatric anesthesia emergence delirium scale Sikich, N. Lerman, J. Anesthesiology 2004

*Anesthesia Recovery Period
Child
Confidence Intervals
Delirium/*diagnosis/*psychology
Humans
Postoperative Complications/*diagnosis/*psychology
Psychometrics


Reference Information

Title
Apolipoprotein E genotype and the association between C-reactive protein and postoperative delirium: Importance of gene-protein interactions
Authors
Vasunilashorn, S. M. Ngo, L. H. Inouye, S. K. Fong, T. G. Jones, R. N. Dillon, S. T. Libermann, T. A. O'Connor, M. Arnold, S. E. Xie, Z. Marcantonio, E. R.
Year
2019
Journal
Alzheimers Dement
Abstract

INTRODUCTION: Apolipoprotein E (APOE) status may modify the risk of postoperative delirium conferred by inflammation. METHODS: We tested whether APOE modifies the established association between C-reactive protein (CRP) and delirium incidence, severity, and duration in 553 noncardiac surgical patients aged 70 and older. High postoperative plasma CRP (>/=234.12 mg/L) was defined by the highest sample-based quartile. Delirium was determined using the Confusion Assessment Method and chart review, and severity was determined by the Confusion Assessment Method–Severity score. RESULTS: APOE epsilon4 carrier prevalence was 19%, and postoperative delirium occurred in 24%. The relationship between CRP and delirium incidence, severity, and duration differed by epsilon4 status. Among epsilon4 carriers, there was a strong relationship between high CRP (vs. low CRP) and delirium incidence (relative risk [95% confidence interval], 3.0 [1.4-6.7]); however, no significant association was observed among non-epsilon4 carriers (relative risk [95% CI], 1.2 [0.8-1.7]). DISCUSSION: Our findings raise the possibility that APOE epsilon4 carrier status may modify the relationship between postoperative day 2 CRP levels and postoperative delirium.

PMID

31761478

Keywords

Apolipoprotein E
C-reactive protein
Delirium
Gene-protein interaction
Inflammation

Page(s)
Issue