What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Non-pharmacological interventions for preventing delirium in hospitalised non-ICU patients (Review)
- Authors
- Burton JK, Craig LE, Yong SQ, Siddiqi N, Teale EA, Woodhouse R, Barugh AJ, Shepherd AM, Brunton A, Freeman SC, Sutton AJ, Quinn TJ
- Year
- 2021
- Journal
- Cochrane Database of Systematic Reviews
- Abstract
Background: Delirium is an acute neuropsychological disorder that is common in hospitalised patients. It can be distressing to patients and carers and it is associated with serious adverse outcomes. Treatment options for established delirium are limited and so prevention of delirium is desirable. Non-pharmacological interventions are thought to be important in delirium prevention. OBJECTIVES: To assess the effectiveness of non-pharmacological interventions designed to prevent delirium in hospitalised patients outside intensive care units (ICU).
Search methods: We searched ALOIS, the specialised register of the Cochrane Dementia and Cognitive Improvement Group, with additional searches conducted in MEDLINE, Embase, PsycINFO, CINAHL, LILACS, Web of Science Core Collection, ClinicalTrials.gov and the World Health Organization Portal/ICTRP to 16 September 2020. There were no language or date restrictions applied to the electronic searches, and no methodological filters were used to restrict the search.
Selection criteria: We included randomised controlled trials (RCTs) of single and multicomponent non-pharmacological interventions for preventing delirium in hospitalised adults cared for outside intensive care or high dependency settings. We only included non-pharmacological interventions which were designed and implemented to prevent delirium. DATA COLLECTION AND ANALYSIS: Two review authors independently examined titles and abstracts identified by the search for eligibility and extracted data from full-text articles. Any disagreements on eligibility and inclusion were resolved by consensus. We used standard Cochrane methodological procedures. The primary outcomes were: incidence of delirium; inpatient and later mortality; and new diagnosis of dementia. We included secondary and adverse outcomes as pre-specified in the review protocol. We used risk ratios (RRs) as measures of treatment effect for dichotomous outcomes and between-group mean differences for continuous outcomes. The certainty of the evidence was assessed using GRADE. A complementary exploratory analysis was undertaker using a Bayesian component network meta-analysis fixed-effect model to evaluate the comparative effectiveness of the individual components of multicomponent interventions and describe which components were most strongly associated with reducing the incidence of delirium.
Main results: We included 22 RCTs that recruited a total of 5718 adult participants. Fourteen trials compared a multicomponent delirium prevention intervention with usual care. Two trials compared liberal and restrictive blood transfusion thresholds. The remaining six trials each investigated a different non-pharmacological intervention. Incidence of delirium was reported in all studies. Using the Cochrane risk of bias tool, we identified risks of bias in all included trials. All were at high risk of performance bias as participants and personnel were not blinded to the interventions. Nine trials were at high risk of detection bias due to lack of blinding of outcome assessors and three more were at unclear risk in this domain. Pooled data showed that multi-component non-pharmacological interventions probably reduce the incidence of delirium compared to usual care (10.5% incidence in the intervention group, compared to 18.4% in the control group, risk ratio (RR) 0.57, 95% confidence interval (CI) 0.46 to 0.71, I2 = 39%; 14 studies; 3693 participants; moderate-certainty evidence, downgraded due to risk of bias). There may be little or no effect of multicomponent interventions on inpatient mortality compared to usual care (5.2% in the intervention group, compared to 4.5% in the control group, RR 1.17, 95% CI 0.79 to 1.74, I2 = 15%; 10 studies; 2640 participants; low-certainty evidence downgraded due to inconsistency and imprecision). No studies of multicomponent interventions reported data on new diagnoses of dementia. Multicomponent interventions may result in a small reduction of around a day in the duration of a delirium episode (mean difference (MD) -0.93, 95% CI -2.01 to 0.14 days, I2 = 65%; 351 participants; low-certainty evidence downgraded due to risk of bias and imprecision). The evidence is very uncertain about the effect of multicomponent interventions on delirium severity (standardised mean difference (SMD) -0.49, 95% CI -1.13 to 0.14, I2=64%; 147 participants; very low-certainty evidence downgraded due to risk of bias and serious imprecision). Multicomponent interventions may result in a reduction in hospital length of stay compared to usual care (MD -1.30 days, 95% CI -2.56 to -0.04 days, I2=91%; 3351 participants; low-certainty evidence downgraded due to risk of bias and inconsistency), but little to no difference in new care home admission at the time of hospital discharge (RR 0.77, 95% CI 0.55 to 1.07; 536 participants; low-certainty evidence downgraded due to risk of bias and imprecision). Reporting of other adverse outcomes was limited. Our exploratory component network meta-analysis found that re-orientation (including use of familiar objects), cognitive stimulation and sleep hygiene were associated with reduced risk of incident delirium. Attention to nutrition and hydration, oxygenation, medication review, assessment of mood and bowel and bladder care were probably associated with a reduction in incident delirium but estimates included the possibility of no benefit or harm. Reducing sensory deprivation, identification of infection, mobilisation and pain control all had summary estimates that suggested potential increases in delirium incidence, but the uncertainty in the estimates was substantial. Evidence from two trials suggests that use of a liberal transfusion threshold over a restrictive transfusion threshold probably results in little to no difference in incident delirium (RR 0.92, 95% CI 0.62 to 1.36; I2 = 9%; 294 participants; moderate-certainty evidence downgraded due to risk of bias). Six other interventions were examined, but evidence for each was limited to single studies and we identified no evidence of delirium prevention. AUTHORS’ CONCLUSIONS: There is moderate-certainty evidence regarding the benefit of multicomponent non-pharmacological interventions for the prevention of delirium in hospitalised adults, estimated to reduce incidence by 43% compared to usual care. We found no evidence of an effect on mortality. There is emerging evidence that these interventions may reduce hospital length of stay, with a trend towards reduced delirium duration, although the effect on delirium severity remains uncertain. Further research should focus on implementation and detailed analysis of the components of the interventions to support more effective, tailored practice recommendations.
- PMID
- Keywords
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Priority areas for outcomes improvement among older adults undergoing inpatient general surgery inclusive of geriatric-pertinent complications | Kazaure, H. S. Johnson, K. S. Rosenthal, R. Lagoo-Deenadayalan, S. | World J Surg | 2024 |
Humans |
| Short-Term Outcome of Patients in Delirium at Medical Intensive Care Unit | Khatri, R. Dhungana, S. Ojha, S. P. Khatri, S. Khadka, S. K, C. P. | J Nepal Health Res Counc | 2024 |
Humans |
| Erythropoietin for the prevention of postoperative neurocognitive disorder in older adult patients undergoing total joint arthroplasty: a randomized controlled study | Kim, E. J. Park, K. K. Choi, S. Y. Ju, H. M. Kim, T. L. Kim, J. Kim, S. Y. Koo, B. N. | BMC Anesthesiol | 2024 |
Humans |
| Multilevel factors influencing falls of older patients in hospital: The risk of hospital-induced delirium and the impact of nurse staffing | Kim, J. Lee, E. Lee, S. | Geriatr Nurs | 2024 |
Delirium |
| Preoperative cognitive training for the prevention of postoperative delirium and cognitive dysfunction: a systematic review and meta-analysis | Lau, K. T. Chiu, L. C. S. Fong, J. S. Y. Chan, A. K. M. Ho, K. M. Lee, A. | Perioper Med (Lond) | 2024 |
Cognitive dysfunction |
| Reinforcement learning model for optimizing dexmedetomidine dosing to prevent delirium in critically ill patients | Lee, H. Y. Chung, S. Hyeon, D. Yang, H. L. Lee, H. C. Ryu, H. G. Lee, H. | NPJ Digit Med | 2024 |
Delirium ICU Dexmedetomidine Artificial Intelligence model for Delirium prevention |
| World delirium awareness and quality survey in 2023-a worldwide point prevalence study | Lindroth, H. Liu, K. Szalacha, L. Ashkenazy, S. Bellelli, G. van den Boogaard, M. Caplan, G. Chung, C. R. Elhadi, M. Gurjar, M. Heras-La-Calle, G. Hoffman, M. Jeitziner, M. M. Krewulak, K. Mailhot, T. Morandi, A. Nawa, R. K. Oh, E. S. Collet, M. O. Paulin | Age Ageing | 2024 |
Humans |
| Effects of melatonin on the prevention of delirium in hospitalized older patients: systematic review and meta-analysis | Liu, L. Ma, X. Song, Z. Li, J. Zhao, Y. Meng, C. Wang, S. Miao, G. Liu, P. | BMC Pharmacol Toxicol | 2024 |
*Melatonin/therapeutic use |
| Pharmacologic prophylaxis of postoperative delirium in elderly patients: A network meta-analysis of randomized controlled trials | Liu, T. H. Lin, Y. T. Wu, J. Y. Huang, P. Y. Tsai, W. W. Lai, C. C. Kao, P. H. Su, K. P. | J Psychiatr Res | 2024 |
Delirium |
| Hospitalization and Hospitalized Delirium Are Associated With Decreased Access to Kidney Transplantation and Increased Risk of Waitlist Mortality | Long, J. J. Hong, J. Liu, Y. Nalatwad, A. Li, Y. Ghildayal, N. Johnston, E. A. Schwartzberg, J. Ali, N. Oermann, E. Mankowski, M. Gelb, B. E. Chanan, E. L. Chodosh, J. L. Mathur, A. Segev, D. L. McAdams-DeMarco, M. A. | Clin Transplant | 2024 |
Humans |
| The impact of patient- and family-centered care interventions on intensive care unit outcomes: a meta-analysis of randomized controlled trials | Lv, Y. Li, P. Li, R. Zhang, T. Cai, K. | Braz J Anesthesiol | 2024 |
Critical care |
| Effect of intraoperative dexmedetomidine on heart-type fatty acid binding protein, CK-MB, and cardiac troponin I levels, and postoperative delirium in patients with heart valve replacement | Ma, Z. Liu, Y. Zhang, C. Li, D. Huo, J. Cao, F. | Am J Transl Res | 2024 |
Dexmedetomidine |
| Experience of carers for older people with delirium: a qualitative study | Mahmoud, A. Raghuraman, S. Richards, E. Morgan-Trimmer, S. Goodwin, V. A. Anderson, R. Allan, L. | Aging Ment Health | 2024 |
Delirium |
| Effects of E-Learning Materials on Caregivers' Knowledge about the 3Ds of Geriatric Psychiatry | Mamayson, R. F. Cawalo, W. P. Morales, E. J. P. Morla, R. X. D. Nebrida, K. L. M. Orca, Z. M. P. Pacolor, L. S. R. Paran, D. P. Ramos, A. Y. P. Razon, E. N. S. Sales, Mmac Soriano, Sjmg Tagorda, Akdi Tingson, R. D. B. | Acta Med Philipp | 2024 |
3Ds |
| Knowledge of Delirium Among ICU Nursing Staff: A Cross-sectional Study | Mathew, C. Ashok, A. V. Punnoose, V. P. | Indian J Psychol Med | 2024 |
Delirium |
| Implementation of Evidence-Based International Recommendations Reduces Postoperative Delirium Rate in Patients Undergoing Cardiac Surgery or Interventions: A System-Based Quality Improvement Study | Milz, S. Holaubek, C. Siebel, J. Hulde, N. Wefer, F. Fruend, A. Tigges-Limmer, K. Gummert, J. von Dossow, V. | Rev Cardiovasc Med | 2024 |
cardiac surgery |
| Inflammatory Indices and Their Associations with Postoperative Delirium | Mintz, G. E. Marcantonio, E. R. Walston, J. D. Dillon, S. T. Jung, Y. Trivedi, S. Gu, X. Fong, T. G. Cavallari, M. Touroutoglou, A. Dickerson, B. C. Jones, R. N. Shafi, M. M. Pascual-Leone, A. Travison, T. G. Inouye, S. K. Libermann, T. A. Ngo, L. H. Vasu | J Gerontol A Biol Sci Med Sci | 2024 |
Cam |
| Efficacy of a melatonin receptor agonist and orexin receptor antagonists in preventing delirium symptoms in the olderly patients with stroke: a retrospective study | Miyoshi, Y. Shigetsura, Y. Hira, D. Maki, T. Kawashima, H. Sugita, N. Sugawara, N. Kitada, N. Hirai, M. Kawata, M. Endo, H. Kojima, Y. Ikuta, K. Katsube, Y. Imayoshi, N. Nakagawa, S. Tsuda, M. Terada, T. | J Pharm Health Care Sci | 2024 |
Delirium |
| A Cross-Sectional Survey on Nurses' Utilization of Risk Assessment and Screening for Postoperative Delirium in Older Patients Following Hip Fracture Surgery in Tertiary Hospitals in Jiangsu Province, China | Yang, J. Liu, M. Yang, L. Fang, S. Wang, G. Gu, Z. | Risk Manag Healthc Policy | 2024 |
delirium |
| Reliability and Validity of Hindi Version of the Confusion Assessment Method for Intensive Care Unit (CAM-ICU) for Diagnosis of Delirium: A Cohort Study | Salhotra, R. Bose, A. Srivastava, S. Mohta, M. Pandarinathan, K. Rautela, R. S. | Indian J Crit Care Med | 2024 |
Critical care |
| Classics in Chemical Neuroscience: Deliriant Antihistaminic Drugs | Nerush, M. O. Shevyrin, V. A. Golushko, N. I. Moskalenko, A. M. Rosemberg, D. B. De Abreu, M. S. Yang, L. E. Galstyan, D. S. Lim, L. W. Demin, K. A. Kalueff, A. V. | ACS Chem Neurosci | 2024 |
Animal models |
| Role of Intraoperative Neurophysiological Monitoring in Predicting Postoperative Delirium in Patients Undergoing Carotid Endarterectomy Surgeries | Al-Qudah, A. M. Sivaguru, S. Anetakis, K. Crammond, D. Balzer, J. Subramaniam, K. Sadhasivam, S. Shandal, V. Thirumala, P. | Eur Neurol | 2024 |
Electroencephalography (EEG) Somatosensory Evoked Potentials (SSEP) Intraoperative neurophysiological monitoring (IONM) Postoperative Delirium Carotid Endarterectomy (CEA) surgery |
| Delirium and frailty in older adults: Clinical overlap and biological underpinnings | Bellelli, G. Triolo, F. Ferrara, M. C. Deiner, S. G. Morandi, A. Cesari, M. Davis, D. Marengoni, A. Inzitari, M. Watne, L. O. Rockwood, K. Vetrano, D. L. | J Intern Med | 2024 |
Humans |
| Adherence to optimal delirium management practices in intensive care units in Brazil: a nationwide survey | Bispo, M. M. Souza, Rcds | JBI Evid Implement | 2024 |
Delirium ICU Delirium prevention Delirium treatment Best practices Adherence |
| Patient- and family-centered care in adult ICU (FAM-ICU): A protocol for a feasibility study | Bohart, S. Waldau, T. Andreasen, A. S. Møller, A. M. Thomsen, T. | Acta Anaesthesiol Scand | 2024 |
family |
| Mortality-related factors in older adults with delirium: A prospective observational study | Boran, Y. Altuncı, Y. A. Yalçınlı, S. | Geriatr Nurs | 2024 |
Delirium |
| A Prospective Observational Cohort Study of Language Preference and Preoperative Cognitive Screening in Older Adults: Do Language Disparities Exist in Cognitive Screening and Does the Association Between Test Results and Postoperative Delirium Differ Base | Canales, C. Ramirez, C. M. Yang, S. C. Feinberg, S. A. Grogan, T. R. Whittington, R. A. Sarkisian, C. Cannesson, M. | Anesth Analg | 2024 |
Humans |
| Machine Learning for Prediction of Postoperative Delirium in Adult Patients: A Systematic Review and Meta-analysis | Chen, H. Yu, D. Zhang, J. Li, J. | Clin Ther | 2024 |
Artificial intelligence |
| A Novel Nomogram Developed Based on Preoperative Immune Inflammation-Related Indicators for the Prediction of Postoperative Delirium Risk in Elderly Hip Fracture Cases: A Single-Center Retrospective Cohort Study | Chen, X. Fan, Y. Tu, H. Chen, J. | J Inflamm Res | 2024 |
elderly |
| Serum Albumin Level at Intensive Care Unit Admission and Delirium Duration and Severity in Critically Ill Adults | Chi, R. Perkins, A. J. Khalifeh, Y. Savsani, P. Jawaid, S. Moiz, S. Wang, S. Khan, S. H. Gao, S. Khan, B. A. | Am J Crit Care | 2024 |
Humans |
| Association between exposure to proton pump inhibitors and delirium: a descriptive and disproportionality analysis of VigiBase | Decros, A. Minoc, E. M. Lelong-Boulouard, V. Chrétien, B. Meurant, A. Alexandre, J. Dolladille, C. Villain, C. | BMJ Open | 2024 |
Humans |
| Nutrition care for older adults with delirium: A scoping review | Deeth, S. Stevens, S. Bell, J. Mudge, A. | J Clin Nurs | 2024 |
Humans |
| Benefits of an automated postoperative delirium risk prediction tool combined with non-pharmacological delirium prevention on delirium incidence and length of stay: a before-after analysis based on a quality improvement project | Dodsworth, B. T. Reeve, K. A. Zozman, M. Meier, P. Buddeberg, F. Möller, M. Wildhaber, S. P. Kedda, M. A. Böttger, S. Stocker, R. Gelsomino, N. S. | Age Ageing | 2024 |
Humans |
| Mechanisms underlying delirium in patients with critical illness | Fan, Y. Y. Luo, R. Y. Wang, M. T. Yuan, C. Y. Sun, Y. Y. Jing, J. Y. | Front Aging Neurosci | 2024 |
cognition impairment |
| Early processed electroencephalography for the monitoring of deeply sedated mechanically ventilated critically ill patients | Favre, E. Bernini, A. Miroz, J. P. Abed-Maillard, S. Ramelet, A. S. Oddo, M. | Nurs Crit Care | 2024 |
Humans |
| Post-operative delirium in different age groups and subtypes: a systematic review of case reports | Guo, J. Guo, X. Liu, W. Zhou, A. Han, J. Yi, R. Dong, L. Zhou, Y. | Front Neurol | 2024 |
acute confusion |
| Delirium diagnostic tools in the postoperative setting: A scoping review protocol | Hansen, C. L. Thomsen, T. Tøgern, A. Møller, A. M. Vester-Andersen, M. Overgaard, S. Foss, N. B. Hägi-Pedersen, D. | Acta Anaesthesiol Scand | 2024 |
Humans |
| Assessment of ICU nurses' competency towards delirium among critically ill patients | Hebeshy, M. I. Gaballah, S. H. Ibrahim, N. M. | BMC Nurs | 2024 |
Attitudes |
| Role of glia in delirium: proposed mechanisms and translational implications | Heffernan Á, B. Steinruecke, M. Dempsey, G. Chandran, S. Selvaraj, B. T. Jiwaji, Z. Stavrou, M. | Mol Psychiatry | 2024 |
Delirium Morbidity and mortality Pathophysiology Glial cells Astrocytes Blood brain barrier |
| Using Machine Learning and Electronic Health Records to Identify Neuropsychiatric Risk Scores for Delirium in ICU and General Hospital Settings | Heikal, M. Saad, H. Ghanime, P. M. Bou Dargham, T. Bizri, M. Kobeissy, F. El Hajj, W. Talih, F. | Neuropsychiatr Dis Treat | 2024 |
Delirium |
| A Study of Knowledge and Recognition on Postoperative Delirium Among Postanesthesia Care Unit (PACU) Nurses | Hsu, Y. C. Wang, S. Y. Su, S. F. Lin, L. W. | J Perianesth Nurs | 2024 |
anesthesia |
| Comparing Bispectral Index Monitoring vs Clinical Assessment for Deep Sedation in the ICU: Effects on Delirium Reduction and Sedative Drug Doses-A Randomized Trial | Huespe, I. Giunta, D. Acosta, K. Avila, D. Prado, E. Sanghavi, D. Bisso, I. C. Giannasi, S. Carini, F. C. | Chest | 2024 |
Humans |
| Assessing the Risk of Postoperative Delirium Through Comprehensive Geriatric Assessment and Eastern Cooperative Oncology Group Performance Status of Elderly Patients With Gastric Cancer | Itami, T. Yamamoto, K. Kurokawa, Y. Saito, T. Takahashi, T. Momose, K. Yamashita, K. Tanaka, K. Makino, T. Yasunobe, Y. Akasaka, H. Fujimoto, T. Yamamoto, K. Nakajima, K. Eguchi, H. Doki, Y. | Ann Surg Oncol | 2024 |
Comprehensive geriatric assessment |
| Efficacy and safety of aripiprazole in the treatment of delirium | Jarosz, M. Badura Brzoza, K. A. | Psychiatr Pol | 2024 |
Humans |
| The hot spots and global trends of prevention and treatment in postoperative delirium (POD) from 2004 to 2023: A bibliometric analysis | Jiang, C. Tian, Z. Jiang, M. Xu, C. Mao, M. Feng, S. Yuan, H. | Surg Open Sci | 2024 |
Bibliometric analysis |
| Impact of the Charlson Comorbidity Index on Delirium Outcomes | Kalyan, P. Parulekar, M. | Cureus | 2024 |
charlson comorbidity index |
| Postoperative pain and neurocognitive outcomes after noncardiac surgery: a systematic review and dose-response meta-analysis | Khaled, M. Sabac, D. Fuda, M. Koubaesh, C. Gallab, J. Qu, M. Lo Bianco, G. Shanthanna, H. Paul, J. Thabane, L. Marcucci, M. | Br J Anaesth | 2024 |
delirium |
| Pharmacological Management of Sleep-Wake Disturbances in Delirium | Levinsohn, E. A. Radhakrishnan, V. Euting, H. Kaplan, G. B. | J Clin Pharmacol | 2024 |
Dora |
| The effect of intraoperative midazolam on postoperative delirium in older surgical patients: a prospective, multicentre cohort study | Li, H. Liu, C. Yang, Y. Wu, Q. P. Xu, J. M. Wang, D. F. Sun, J. J. Mao, M. M. Lou, J. S. Liu, Y. H. Cao, J. B. Duan, C. Y. Mi, W. D. | Anesthesiology | 2024 |
Midazolam Benzodiazepine Postoperative Delirium Non-cardiac surgery 3D-CAM |
| Family involvement in preventing delirium in critically ill patients: A systematic review and meta-analysis | Li, J. Fan, Y. Luo, R. Wang, Y. Yin, N. Qi, W. Huang, T. Zhang, J. Jing, J. | Int J Nurs Stud | 2024 |
Critical illness |
| Assessing the Risk of Delirium and Death in Sepsis Using the Braden Score: A Retrospective Study | Li, X. Tang, Y. Bai, Z. Liang, X. Huang, X. Chen, J. Cheng, H. Lyu, J. Wang, Y. | J Clin Nurs | 2024 |
Braden score |
| Nutritional Status and Inflammation as Mediators of Physical Performance and Delirium in Elderly Community-Acquired Pneumonia Patients: A Retrospective Cohort Study | Liao, J. Shen, X. Du, Z. Wang, X. Miao, L. | Clin Interv Aging | 2024 |
Humans |
| Predicting delirium in older adults with community-acquired pneumonia: A retrospective analysis of stress hyperglycemia ratio and its interactions with nutrition and inflammation | Liao, J. Xie, C. Shen, X. Miao, L. | Arch Gerontol Geriatr | 2024 |
Community-acquired pneumonia |
| A Comprehensive Intervention Program for Postoperative Delirium Prevention in Elderly Patients Undergoing Cardiac Surgery | Lin, H. Dong, D. Zheng, K. Xu, Q. | J Perianesth Nurs | 2024 |
evidence-based medicine |
| Delirium in the United States: Results From the 2023 Cross-Sectional World Delirium Awareness Day Prevalence Study | Lindroth, H. Byrnes, T. Fuchita, M. Hetland, B. Liu, K. Maya, K. McAndrew, N. S. Mulkey, M. A. Nydahl, P. Palakshappa, J. von Haken, R. Psoter, K. J. Oh, E. S. | J Acad Consult Liaison Psychiatry | 2024 |
Humans |
| Projection of visual material on postoperative delirium in patients undergoing cardiac surgery: A double blind randomized clinical trial | Méndez-Martínez, C. Casado-Verdejo, I. Fernández-Fernández, J. A. Sánchez-Valdeón, L. Bello-Corral, L. Méndez-Martínez, S. Sandoval-Diez, A. Gómez-Salgado, J. García-Suárez, M. Fernández-García, D. | Medicine (Baltimore) | 2024 |
Humans |
| Prehabilitation for delirium prevention in elderly patients with chronic limb threatening ischemia | Meulenbroek, A. L. Lanssens, G. Fourneau, I. Buimer, M. G. de Groot, H. G. W. Veen, E. J. Ho, G. H. van Gorkom, R. Toonders, F. Steyerberg, E. W. Faes, M. C. van der Laan, L. van Alphen, R. Jiran, T. van Overveld, K. Pijl, M. Verbogt, N. | J Vasc Surg | 2024 |
Chronic Limb Threatening Ischemia |
| Nutritional status and triglyceride-glucose index influence delirium in elderly heart failure patients | Miao, L. Shen, X. Du, Z. Liao, J. | Sci Rep | 2024 |
Humans |
| The association of pre-operative biomarkers of endothelial dysfunction with the risk of post-operative neurocognitive disorders: results from the BioCog study | Moazzen, S. Janke, J. Slooter, A. J. C. Winterer, G. Spies, C. Pischon, T. Feinkohl, I. | BMC Anesthesiol | 2024 |
Humans |
| Clinician and Visitor Activity Patterns in an Intensive Care Unit Room: A Study to Examine How Ambient Monitoring Can Inform the Measurement of Delirium Severity and Escalation of Care | Nalaie, K. Herasevich, V. Heier, L. M. Pickering, B. W. Diedrich, D. Lindroth, H. | J Imaging | 2024 |
computer vision |
| Incidence of delirium in ophthalmology | Ngo, Q. Böhringer, D. Agostini, H. Lapp, T. Reinhard, T. | Ophthalmologie | 2024 |
Humans |
| Self-efficacy of ICU nurses in delirium care: an analysis of the current status and influencing factors | Nie, J. Li, W. J. Jiang, Z. Y. | BMC Nurs | 2024 |
Delirium |
| Association between intraoperative electroencephalogram burst suppression and postoperative delirium: A systematic review and meta-analysis | Park, S. K. Han, D. W. Chang, C. H. Jung, H. Kang, H. Song, Y. | Anesthesiology | 2024 |
Electroencephalogram burst suppression Postoperative delirium Anesthesia Intraoperative bust suppression |
| Association of preoperative to postoperative change in cerebrospinal fluid fibrinogen with postoperative delirium | Payne, T. Taylor, J. Kunkel, D. Konieczka, K. Ingram, F. Blennow, K. Zetterberg, H. Pearce, R. A. Meyer-Franke, A. Terrando, N. Akassoglou, K. Sanders, R. D. Lennertz, R. C. | BJA Open | 2024 |
anaesthesia |
| Risk factors for postoperative delirium in adult patients undergoing cardiopulmonary bypass in cardiac surgery | Pei, W. Tan, H. Dai, T. Liu, J. Tang, Y. Liu, J. | Am J Transl Res | 2024 |
Cardiopulmonary bypass in cardiac surgery |
| Impact of Dexmedetomidine on Hemodynamics, Plasma Catecholamine Levels, and Delirium Incidence Among Intubated Patients in the ICU--A Randomized Controlled Trial | Qiao, L. Wang, Z. Shen, J. Xing, X. Yuan, H. | Ther Clin Risk Manag | 2024 |
delirium |
| Postoperative Delirium and Neurocognitive Disorders: Updates for Providers Caring for Cancer Patients | Ron, D. Deiner, S. | Curr Oncol Rep | 2024 |
Humans |
| Core outcome set for studies evaluating interventions to prevent or treat delirium in long-term care older residents: international key stakeholder informed consensus study | Russell, G. Rana, N. Reilly, S. T. Shehadeh, A. Page, V. Siddiqi, N. Rose, L. | Age Ageing | 2024 |
Humans |
| Nonpharmacological Prevention and Management of Delirium: Past, Present, and Future | Ryan, S. L. | Semin Neurol | 2024 |
delirium EHR artificial intelligence risk factors |
| Cerebrovascular pulsatility indicates preoperative subcortical cognitive impairment and an increased risk for postoperative delirium in elderly patients undergoing elective spine surgery | Saar, A. Müller, J. Veser, Y. Behr, F. Rathmann, E. Schroeder, H. W. S. Flöel, A. Müller, J. U. von Sarnowski, B. Fleischmann, R. | Front Med (Lausanne) | 2024 |
carotid ultrasound |
| Delirium and Weakness Acquired in the Intensive Care Unit: Individual and Combined Effects on 90-Day Mortality in Survivors of Critical Illness | Siao, S. F. Zheng, Y. Y. Wei, Y. C. Boehm, L. M. Chen, C. C. | J Clin Nurs | 2024 |
delirium |
| The Pathophysiology and Biomarkers of Delirium | Smith, C. J. Hodge, D. Harrison, F. E. Williams Roberson, S. | Semin Neurol | 2024 |
delirium biomarkers neuroimaging electroencephalography therapeutic targets |
| ACR Appropriateness Criteria® Altered Mental Status, Coma, Delirium, and Psychosis: 2024 Update | Soares, B. P. Shih, R. Y. Utukuri, P. S. Adamson, M. Austin, M. J. Brown, R. K. J. Burns, J. Cacic, K. Chu, S. Crone, C. Ivanidze, J. Jackson, C. D. Kalnins, A. Potter, C. A. Rosen, S. Soderlund, K. A. Thaker, A. A. Wang, L. L. Policeni, B. | J Am Coll Radiol | 2024 |
Humans |
| Refining Research Diagnostic Criteria for Catatonia Among Delirium, Medical, Affective, and Psychosis Patient Groups | Trzepacz, P. T. Franco, J. G. Chakrabarti, S. Ghosh, A. Sahoo, S. Chakravarty, R. Grover, S. | J Neuropsychiatry Clin Neurosci | 2024 |
Affective Disorder |
| Improving the Recognition and Assessment of ICU Delirium | Tuomisto, A. Kennedy, P. | J Contin Educ Nurs | 2024 |
*Delirium/diagnosis/prevention & control |
| The Relationship between Delirium and Dementia | Umoh, M. E. Fitzgerald, D. Vasunilashorn, S. M. Oh, E. S. Fong, T. G. | Semin Neurol | 2024 |
delirium dementia risk factor |
| Detecting and managing cognitive impairment in cardiac patients: insights from qualitative interviews with nurses | Zhao, E. Bloomfield, J. Lowres, N. Gallagher, R. | Contemp Nurse | 2024 |
barriers |
| The Management and Prevention of Delirium in Elderly Patients Hospitalised in Intensive Care Units: A Systematic Review | Zaher-Sánchez, S. Satústegui-Dordá, P. J. Ramón-Arbués, E. Santos-Sánchez, J. A. Aguilón-Leiva, J. J. Pérez-Calahorra, S. Juárez-Vela, R. Sufrate-Sorzano, T. Angulo-Nalda, B. Garrote-Cámara, M. E. Santolalla-Arnedo, I. Echániz-Serrano, E. | Nurs Rep | 2024 |
Icu |
| Pharmacological Prevention of Postoperative Delirium in Adults: A Review of Recent Literature | White, N. C. Cowart, C. R. Cios, T. J. | Curr Neurol Neurosci Rep | 2024 |
Anesthesia |
| DELirium treatment with Transcranial Electrical Stimulation (DELTES): study protocol for a multicentre, randomised, double-blind, sham-controlled trial | van der, A. J. Lodema, Y. Ottens, T. H. Schutter, Djlg Emmelot-Vonk, M. H. de Haan, W. van Dellen, E. Tendolkar, I. Slooter, A. J. C. | BMJ Open | 2024 |
Humans |
| Delirium risk and mortality in people with pre-existing severe mental illness: a retrospective cohort study using linked datasets in England | Bauernfreund, Y. Launders, N. Favarato, G. Hayes, J. F. Osborn, D. Sampson, E. L. | Psychol Med | 2024 |
Schizophrenia |
| Factors Affecting Delirium Care Core Competency Among Nurses: A Descriptive Correlational Study | Bae, K. S. Roh, Y. S. | Nurs Health Sci | 2024 |
Humans |
| Understanding Barriers to Early Rehabilitation Following the Surgery for Fragility Hip Fractures: A Single-Centre Audit | Al-Dahan, T. Murhekar, S. Abed, M. Shinde, K. | Cureus | 2024 |
delerium |
| The Association of Selective Serotonin Reuptake Inhibitors with Delirium in Post-Operative Adults: A Secondary Analysis of a Post-Operative Dataset with Daily Severity of Illness Adjustment | Austin, C. A. Bazemore, I. Yi, J. Glier, S. Carson, S. S. | Delirium Commun | 2024 |
Delirium |
| Evaluation of the effects of a team-based systematic prevention and management program for postoperative orthopedic older patients: A retrospective cohort study | Yamaguchi, F. Inomata, C. Yoshinaga, N. Sawada, H. Shimamoto, K. Haruta-Tsukamoto, A. | PCN Rep | 2024 |
delirium |
| Incidence of Delirium in ICU Patients With and Without COVID-19 in a Costa Rican Hospital | Zavaleta-Monestel, E. Martínez-Vargas, E. Chaverri-Fernández, J. Díaz-Madriz, J. P. Fallas-Mora, A. Alvarado-Ajun, P. Rojas-Chinchilla, C. García-Montero, J. | Cureus | 2024 |
covid-19 |
| The associations of post-stroke delirium with outcomes: a systematic review and meta-analysis | Zhang, G. B. Lv, J. M. Yu, W. J. Li, H. Y. Wu, L. Zhang, S. L. Shi, G. Z. Huang, H. W. | BMC Med | 2024 |
Humans |
| Preoperative frailty tendency predicts delirium occurrence in older people undergoing spinal surgery | Zhang, Y. Zhang, X. Qi, P. Lu, J. Yang, M. | BMC Geriatr | 2024 |
Humans |
| Systemic immune inflammatory index (SII) and systemic inflammatory response index (SIRI) as predictors of postoperative delirium in patients undergoing off-pump coronary artery bypass grafting (OPCABG) with cerebral infarction | Zhao, B. S. Zhai, W. Q. Ren, M. Zhang, Z. Han, J. G. | BMC Surg | 2024 |
Humans |
| How to predict postoperative delirium in geriatric patients with hip fracture as soon as possible? A retrospective study | Zhao, S. Sun, T. Zhang, J. Wang, Y. Guo, Y. Wang, X. | BMC Surg | 2024 |
Humans |
| Clinical investigation into risk factors for delirium post-cardiac surgery and its implications for nursing intervention guided by behavior change theory | Zhao, Y. Guo, S. Wang, Z. Dong, Y. Wei, W. Su, Z. | J Cardiothorac Surg | 2024 |
Humans |
| Incidence and risk factors of postoperative delirium in lumbar spinal fusion patients: A National Database analysis | Zheng, Y. Wang, J. Liu, Z. Wang, J. Yang, Q. Ren, H. Feng, L. | World Neurosurg | 2024 |
Lumbar fusion |
| Translation, cultural debugging, and validation of the Chinese version of the Sour Seven Questionnaire: a cross-sectional study | Zhu, S. Liu, S. Li, L. Xing, H. Xia, M. Dong, G. | Front Med (Lausanne) | 2024 |
Chinese version |
| Psychiatric Etiologies and Approaches in Altered Mental Status Presentations: Insights from Consultation Liaison Psychiatry | Hamm, B. Rosenthal, L. J. | Semin Neurol | 2024 |
Altered mental status Psychiatry Delirium
|
| Bispectral Index Monitoring Effect on Delirium Occurrence and Nursing Quality Improvement in Post-anesthesia Care Unit Patients Recovering From General Anesthesia: A Randomized Controlled Trial | Huang, Y. Huang, L. Xu, J. Bao, Y. Qu, Y. Huang, Y. | Cureus | 2024 |
bispectral index |
| Impact of Frailty and Delirium Among Older Adults Admitted With Acute Decompensated Heart Failure | Irizarry-Caro, J. A. Kumar, M. Wang, Q. Rohant, N. Goyal, P. Damluji, A. A. Kirkpatrick, J. N. Kwak, M. J. | JACC Adv | 2024 |
acute decompensated heart failure |
| Improving hospice delirium guideline adoption through an understanding of barriers and facilitators: A mixed-methods study | Jackson, C. Malia, C. Zacharias, H. Dyson, J. Johnson, M. J. | PLoS One | 2024 |
Humans |
| Machine learning-based delirium prediction in surgical in-patients: a prospective validation study | Jauk, S. Kramer, D. Sumerauer, S. Veeranki, S. P. K. Schrempf, M. Puchwein, P. | JAMIA Open | 2024 |
clinical decision support
delirium
electronic health records
prediction algorithms
random forest
|
| Risk factors for postoperative delirium in patients with cardiac surgery | Kim, M. S. Kim, S. H. | Sci Prog | 2024 |
Humans |
| Delirium in the ICU: how much do we know? A narrative review | Liu, S. B. Wu, H. Y. Duan, M. L. Yang, R. L. Ji, C. H. Liu, J. J. Zhao, H. | Ann Med | 2024 |
*Delirium/diagnostic imaging/pathology/therapy |