What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Safety and Tolerability of Rapid Administration Undiluted Levetiracetam
- Authors
- Morgan, O. Medenwald, B.
- Year
- 2020
- Journal
- Neurocrit Care
- Abstract
BACKGROUND/OBJECTIVE: Levetiracetam (LEV) is an antiepileptic drug used widely in patients with a favorable safety profile. Studies evaluating the safety and efficacy of intravenous (IV) LEV included volumes of at least 100 mL. Minimally diluted doses administered over 5-6 min were found to be both safe and effective. Given the complexities of admixing, this practice can be impractical and result in delays in antiepileptic therapy. This study aimed to retrospectively review the safety and tolerability of rapid administration of undiluted LEV doses </= 1000 mg. METHODS: This was a retrospective study evaluating adverse drug reactions associated with undiluted LEV from January 1, 2018-June 1, 2018. Patients were included if they received at least one dose of undiluted LEV and were >/= 18 years old. Safety endpoints were reviewed and collected from the time administration until hospital discharge. Endpoints included injection site pain and discomfort, injection site erythema, extravasation, IV line replacement, and any documented adverse effect leading to IV LEV discontinuation. Descriptive statistics were used to analyze the data. RESULTS: A total of 199 patients were included in the study totaling 1626 doses of LEV. Most patients were administered LEV 1000 mg (60.8%), through a peripheral line (64.3%), and were prescribed LEV for seizure prophylaxis (58.3%). Patients received a mean of 8.1 +/- 8 doses for a mean duration of therapy of 5 +/- 4.5 days. About 98.5% of patients did not experience an adverse effect, whereas 1.5% of patients experienced agitation, delirium, confusion, and/or lethargy, which is well known to LEV therapy. CONCLUSIONS: Rapid administration of undiluted LEV doses </= 1000 mg were well tolerated with no concentration-related side effects. Further prospective research is needed to confirm this observation as well as the safety of higher doses.
- PMID
- Keywords
Anticonvulsants
Humans
Intravenous
- Page(s)
- 131-134
- Volume
- 32
- Issue
- 1
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Rest-activity patterns associated with delirium in patients with intracerebral hemorrhage | Reznik, M. E. Mintz, N. Moody, S. Drake, J. Margolis, S. A. Rudolph, J. L. LaBuzetta, J. N. Kamdar, B. B. Jones, R. N. | J Neurol Sci | 2023 |
Humans |
| Development and validation of delirium prediction models for noncardiac surgery patients | Rössler, J. Shah, K. Medellin, S. Turan, A. Ruetzler, K. Singh, M. Sessler, D. I. Maheshwari, K. | J Pain Palliat Care Pharmacother | 2023 |
Anesthesia |
| Effects of Opioids, Steroids, Benzodiazepines, Anticholinergics, and Antihistamines on the Efficacy of Antipsychotics for Treating Delirium in End-of-Life Adult Patients Undergoing Palliative Care | Sato, J. Tanaka, R. | J Pain Palliat Care Pharmacother | 2023 |
Humans |
| Clinical Prediction Models for Hospital-Induced Delirium Using Structured and Unstructured Electronic Health Record Data: Protocol for a Development and Validation Study | Ser, S. E. Shear, K. Snigurska, U. A. Prosperi, M. Wu, Y. Magoc, T. Bjarnadottir, R. I. Lucero, R. J. | JMIR Res Protoc | 2023 |
big data |
| A Prospective Randomized Study of the Herbal Medicine Yokukansan for Preventing Delirium After Gastrointestinal Cancer Surgery | Tanio, A. Yamamoto, M. Uejima, C. Tada, Y. Yamanashi, T. Matsuo, R. Miura, A. Kajitani, N. Nishiguchi, T. Iwata, M. Fujiwara, Y. | Yonago Acta Med | 2023 |
gastrointestinal cancer |
| A protocol of an international validation study to assess the clinical accuracy of the eDIS-ICU delirium screening tool | Tronstad, O. Patterson, S. Sutt, A. L. Pearse, I. Hay, K. Liu, K. Sato, K. Koga, Y. Matsuoka, A. Hongo, T. Rätsep, I. Fraser, J. F. Flaws, D. | Aust Crit Care | 2023 |
Humans |
| Anaesthesia-related cognitive dysfunction following cardiothoracic surgery in late middle-age and younger adults: A scoping review | Varpaei, H. A. Robbins, L. B. Ling, J. Lehto, R. H. Bender, C. M. | Nurs Crit Care | 2023 |
anaesthesia |
| Long-term mortality of critically ill patients with cancer and delirium who survived to discharge: a retrospective cohort study | Vizzacchi, B. A. Pezzini, T. R. de Souza, J. M. Caruso, P. Nassar, A. P., Jr. | Can J Anaesth | 2023 |
Adult |
| The effect of anesthetic depth on postoperative delirium in older adults: a systematic review and meta-analysis | Wang, Y. Zhu, H. Xu, F. Ding, Y. Zhao, S. Chen, X. | BMC Geriatr | 2023 |
Humans |
| Unveiling the nexus of postoperative fever and delirium in cardiac surgery: identifying predictors for enhanced patient care | Wang, Y. P. Shen, B. B. Zhu, C. C. Li, L. Lu, S. Wang, D. J. Jin, H. Liu, Q. Wang, Z. Y. Ge, M. | Front Cardiovasc Med | 2023 |
Cpb |
| Long-term cognitive impairment after probable delirium in long-term care residents: A population-based retrospective cohort study | Webber, C. Milani, C. Pugliese, M. Lawlor, P. G. Bush, S. H. Watt, C. Casey, G. Knoefel, F. Thavorn, K. Momoli, F. Tanuseputro, P. | J Am Geriatr Soc | 2023 |
cognitive decline |
| Delirium Due to Potentially Avoidable Hospitalizations Among Older Adults | Whittington, C. Skains, R. M. Zhang, Y. Osborne, J. D. O'Leary, T. Freeman, H. B. Martin, R. C. Vickers, J. K. Flood, K. L. Markland, A. D. Buford, T. W. Brown, C. J. Kennedy, R. E. | J Gerontol A Biol Sci Med Sci | 2023 |
ambulatory care sensitive conditions |
| Quantitative electroencephalography predicts postoperative delirium in cardiac surgical patients after cardiopulmonary bypass: a prospective observational study | Xue, Y. Liu, W. Su, L. He, H. Chen, H. Long, Y. | Front Med (Lausanne) | 2023 |
cardiopulmonary bypass |
| Natural language processing to assess the epidemiology of delirium-suggestive behavioural disturbances in critically ill patients | Young, M. Holmes, N. Robbins, R. Marhoon, N. Amjad, S. Neto, A. S. Bellomo, R. | Crit Care Resusc | 2021 |
Background: There is no gold standard approach for delirium diagnosis, making the assessment of its epidemiology difficult. Delirium can only be inferred though observation of behavioural disturbance and described with relevant nouns or adjectives. Objective: We aimed to use natural language processing (NLP) and its identification of words descriptive of behavioural disturbance to study the epidemiology of delirium in critically ill patients. Study design: Retrospective study using data collected from the electronic health records of a university-affiliated intensive care unit (ICU) in Melbourne, Australia. Participants: 12 375 patients Intervention: Analysis of electronic progress notes. Identification using NLP of at least one of a list of words describing behavioural disturbance within such notes. Results: We analysed 199 648 progress notes in 12 375 patients. Of these, 5108 patients (41.3%) had NLP-diagnosed behavioural disturbance (NLP-Dx-BD). Compared with those who did not have NLP-Dx-DB, these patients were older, more severely ill, and likely to have medical or unplanned admissions, neurological diagnosis, chronic kidney or liver disease and to receive mechanical ventilation and renal replacement therapy (P < 0.001). The unadjusted hospital mortality for NLP-Dx-BD patients was 14.1% versus 9.6% for patients without NLP-Dx-BD. After adjustment for baseline characteristics and illness severity, NLP-Dx-BD was not associated with increased risk of death (odds ratio [OR], 0.94; 95% CI, 0.80-1.10); a finding robust to multiple sensitivity, subgroups and time of observation subcohort analyses. In mechanically ventilated patients, NLP-Dx-BD was associated with decreased hospital mortality (OR, 0.80; 95% CI, 0.65-0.99) after adjustment for baseline severity of illness and year of admission. Conclusions: NLP enabled rapid assessment of large amounts of data identifying a population of ICU patients with typical high risk characteristics for delirium. Moreover, this technique enabled identification of previously poorly understood associations. Further investigations of this technique appear justified. |
| Association between intraoperative mean arterial pressure variability and postoperative delirium after hip fracture surgery: a retrospective cohort study | Zhang, C. Song, Y. Wu, X. Miao, R. Lou, J. Ma, Y. Li, M. Mi, W. Cao, J. | BMC Geriatr | 2023 |
Aged |
| Impact of Clinical Decision Support System Assisted prevention and management for Delirium on guideline adherence and cognitive load among Intensive Care Unit nurses (CDSSD-ICU): Protocol of a multicentre, cluster randomized trial | Zhang, S. Ding, S. Cui, W. Li, X. Wei, J. Wu, Y. | Int J Nurs Stud | 2023 |
Humans |
| Non-pharmacological interventions to prevent and treat delirium in older people: An overview of systematic reviews | Zhao, Q. Liu, S. Zhao, H. Dong, L. Zhu, X. Liu, J. | Int J Nurs Stud | 2023 |
Humans |
| Online interpretable dynamic prediction models for postoperative delirium after cardiac surgery under cardiopulmonary bypass developed based on machine learning algorithms: A retrospective cohort study | Zhao, X. Li, J. Xie, X. Fang, Z. Feng, Y. Zhong, Y. Chen, C. Huang, K. Ge, C. Shi, H. Si, Y. Zou, J. | J Psychosom Res | 2023 |
Cardiac surgery |
| Dementia and Postoperative Delirium in Surgical Hip Fracture Patients: Unveiling Contrasting Risk Factors and Implications | Zhao, Y. Alderden, J. Missbrenner, N. | J Gerontol Nurs | 2023 |
Humans |
| Diagnostic accuracy of the Family Confusion Assessment Method for delirium detection: A systematic review and meta-analysis | Zhou, C. Wang, H. Wang, L. Zhou, Y. Wu, Q. | J Am Geriatr Soc | 2023 |
Fam-cam |
| The effects of a multidisciplinary pathway for perioperative management of patients with hip fracture | Ackermann, L. L. Schwenk, E. S. Li, C. J. Vaile, J. R. Weitz, H. | Hosp Pract (1995) | 2023 |
Humans, Aged, Analgesics, Opioid/therapeutic use, Prospective Studies |
| Precision-based approaches to delirium in critical illness: A narrative review | Ankravs, M. J. McKenzie, C. A. Kenes, M. T. | Pharmacotherapy | 2023 |
Humans, Delirium/diagnosis/drug therapy/etiology, Intensive Care Units |
| Associations between early in-hospital medications and the development of delirium in patients with stroke | Ryan, S. L. Liu, X. McKenna, V. Ghanta, M. Muniz, C. Renwick, R. Westover, M. B. Kimchi, E. Y. | J Stroke Cerebrovasc Dis | 2023 |
Humans |
| Family-centered delirium prevention and treatment using video calls: the FACE Delirium trial | Trabert, J. Schenk, A. Golbach, R. Püllen, R. Schütze, S. | Eur Geriatr Med | 2023 |
Delirium |
| Early Onset Delirium During Hospitalization Increases In-Hospital and Postdischarge Mortality in COVID-19 Patients: A Multicenter Prospective Study | Trevisan, C. Grande, G. Rebora, P. Zucchelli, A. Valsecchi, M. G. Focà, E. Ecarnot, F. Marengoni, A. Bellelli, G. | J Clin Psychiatry | 2023 |
Humans |
| Accuracy of a clinical decision support system based on the 3-minute diagnostic interview for CAM-defined delirium: A validation study(✰) | Wang, J. Ji, M. Huang, Y. Yang, F. Wu, Y. | Geriatr Nurs | 2023 |
Humans |
| Psychological stress and associated factors in caring for patients with delirium among intensive care unit nurses: A cross-sectional study | Wang, Y. Li, L. Tan, S. Guan, Y. Luo, X. | Aust Crit Care | 2023 |
Humans |
| Inflammatory biomarkers and delirium: a Mendelian randomization study | Yu, M. Li, Y. Li, B. Ge, Q. | Front Aging Neurosci | 2023 |
Il-6
|
| Knowledge, attitude and practice regarding hypoactive delirium among ICU nurses: A nationwide cross-sectional study | Yu, M. Mi, J. Zhang, C. Chen, H. Luo, X. | Nurse Educ Pract | 2023 |
Attitude |
| Potentials of Acetylcholinesterase and Butyrylcholinesterase Alterations in On-Pump Coronary Artery Bypass Surgery in Postoperative Delirium: An Observational Trial | Zajonz, T. S. Kunzemann, C. Schreiner, A. L. Beckert, F. Schneck, E. Boening, A. Markmann, M. Sander, M. Koch, C. | J Clin Med | 2023 |
cardiac surgery |
| Peripheral cholinesterase activity is not correlated with postoperative delirium in urological surgery | Zangl, Q. Sprinz, B. von Dossow, V. | J Perioper Pract | 2023 |
Acetylcholinesterase |
| Biologic correlates associated with poor functional recovery after delirium: A nested prospective cohort study | Dasgupta, M. Brymer, C. | Health Sci Rep | 2023 |
activities of daily living |
| ICU Delirium Is Associated with Cardiovascular Burden and Higher Mortality in Patients with Severe COVID-19 Pneumonia | Gutowski, M. Klimkiewicz, J. Michałowski, A. Ordak, M. Możański, M. Lubas, A. | J Clin Med | 2023 |
Covid-19 |
| Analysis of risk factors for postoperative delirium in middle-aged and elderly fracture patients in the perioperative period | An, Z. Xiao, L. Chen, C. Wu, L. Wei, H. Zhang, X. Dong, L. | Sci Rep | 2023 |
Aged |
| Korkatti-Puoskari, N. Tiihonen, M. Caballero-Mora, M. A. Topinkova, E. Szczerbińska, K. Hartikainen, S. | Therapeutic dilemma's: antipsychotics use for neuropsychiatric symptoms of dementia, delirium and insomnia and risk of falling in older adults, a clinical review | Eur Geriatr Med | 2023 |
Humans |
| The efficacy and safety of haloperidol for the treatment of delirium in critically ill patients: a systematic review and meta-analysis of randomized controlled trials | Huang, J. Zheng, H. Zhu, X. Zhang, K. Ping, X. | Front Med (Lausanne) | 2023 |
Icu |
| A prospective randomized study examining the impact of intravenous versus inhalational anesthesia on postoperative cognitive decline and delirium | Farrer, T. J. Monk, T. G. McDonagh, D. L. Martin, G. Pieper, C. F. Koltai, D. | Appl Neuropsychol Adult | 2023 |
Anesthesia type |
| Factors Associated with Improvement in Activities of Daily Living during Hospitalization: A Retrospective Study of Older Patients with Hip Fractures | Takeda, K. Wada, M. Yorozuya, K. Hara, Y. Watanabe, T. Hanaoka, H. | Ann Geriatr Med Res | 2023 |
Activities of daily living |
| Associations Between Dysphagia and Adverse Health Outcomes in Older Adults with Dementia in Intensive Care Units: A Retrospective Cohort Study | Cheng, H. Deng, X. Li, J. Tang, Y. Yuan, S. Huang, X. Wang, Z. Zhou, F. Lyu, J. | Clin Interv Aging | 2023 |
Humans |
| Microvascular reconstruction for oral cancer in older adult patients: the impact of age on surgical outcomes | Kouketsu, A. Kaneuji, T. Yamaguma, Y. Yamauchi, K. Sugiura, T. Takahashi, T. Ito, H. Yamashita, Y. | Oral Surg Oral Med Oral Pathol Oral Radiol | 2023 |
oral, cancer, surgical, adults, elderly |
| Postoperative delirium is a risk factor of institutionalization after hip fracture: an observational cohort study | Labaste, F. Delort, F. Ferré, F. Bounes, F. Reina, N. Valet, P. Dray, C. Minville, V. | Front Med (Lausanne) | 2023 |
delirium |
| Prognostic significance of delirium in patients with heart failure: a systematic review and meta-analysis | Niu, Z. Zhou, J. Li, Y. | Front Cardiovasc Med | 2023 |
delirium |
| Postoperative delirium in 47 379 individuals undergoing transcatheter aortic valve replacement: a systematic review and meta-analysis | Ochani, S. Adnan, A. Siddiqui, A. Kalwar, A. Kukreja, S. Ahmad, M. Ashraf, M. H. Asghar, M. A. | Ann Med Surg (Lond) | 2023 |
Cam, Tavr, confusion assessment method, delirium, stroke, transcatheter aortic valve replacement |
| ICU Readmission in Injured Older Adults: Modifiable Risk Factors and Implications | Agoubi, L. L. Reimel, B. A. Maine, R. G. O'Connell, K. M. Maier, R. V. McIntyre, L. K. | J Trauma Acute Care Surg | 2023 |
ICU, delirium, older adults, risk factors, readmission |
| Motorist disorientation syndrome; clinical features and vestibular findings | Ainsworth, C. Davies, R. Colvin, I. Murdin, L. | J Vestib Res | 2023 |
Humans |
| External validity of an automated delirium prediction model (DEMO) and comparison to the manual VMS-questions: a retrospective cohort study | Ali, M. I. M. Kalkman, G. A. Wijers, C. H. W. Fleuren, Hwha Kramers, C. de Wit, Hajm | Int J Clin Pharm | 2023 |
Humans |
| Role of Intraoperative Neuromonitoring to Predict Postoperative Delirium in Cardiovascular Surgery | Al-Qudah, A. M. Ta'ani, O. A. Thirumala, P. D. Sultan, I. Visweswaran, S. Nadkarni, N. Kiselevskaya, V. Crammond, D. J. Balzer, J. Anetakis, K. M. Shandal, V. Subramanium, K. Subramanium, B. Sadhasivam, S. | J Cardiothorac Vasc Anesth | 2023 |
Eeg, Ionm, Ssep, cardiac, delirium, postoperative |
| Comparison of the hemodynamic effects of opioid-based versus lidocaine-based induction of anesthesia with propofol in older adults: a randomized controlled trial | Amin, S. M. Hasanin, A. ElSayed, O. S. Mostafa, M. Khaled, D. Arafa, A. S. Hassan, A. | Anaesth Crit Care Pain Med | 2023 |
Humans |
| Effect of pharmacist-led intervention protocol on preventing postoperative delirium after elective cardiovascular surgery | Asai, Y. Yanagawa, T. Takahashi, M. | PLoS One | 2023 |
Adult, Humans, *Emergence Delirium, Pharmacists, Retrospective Studies, Benzodiazepines/adverse effects |
| Taming Postoperative Delirium with Dexmedetomidine: A Review of the Therapeutic Agent's Neuroprotective Effects following Surgery | Bargnes, V., 3rd Oliver, B. Wang, E. Greenspan, S. Jin, Z. Yeung, I. Bergese, S. | Pharmaceuticals (Basel) | 2023 |
dexmedetomidine |
| Level of implementation of pain management and early mobilization strategies to prevent delirium in geriatric trauma patients: A mixed-methods study | Beaudoin, M. Belzile, E. L. Gélinas, C. Trépanier, D. Émond, M. Gagnon, M. A. Bérubé, M. | Int J Orthop Trauma Nurs | 2023 |
Delirium, Early mobilization, Geriatric trauma, Mixed-methods, Pain management, Practice guidelines |
| Dose-dependent QTc interval prolongation under haloperidol and pipamperone in the management of delirium in a naturalistic setting | Bohny, P. Boettger, S. Jenewein, J. | Front Psychiatry | 2023 |
QTc interval, delirium, haloperidol, pipamperone, torsades de pointes |
| Prevalence and risk factors of subsyndromal delirium among postoperative patients: A systematic review and meta-analysis | Chen, S. Tang, L. Chen, J. Cai, L. Liu, C. Song, J. Chen, Y. Liu, Y. Zheng, S. | J Adv Nurs | 2023 |
Subsyndromal delirium, meta-analysis, nurse, nursing, postoperative care, prevalence, risk factors, surgery |
| Incidence change of postoperative delirium after implementation of processed electroencephalography monitoring during surgery: a retrospective evaluation study | Chen, Y. C. Hung, I. Y. Hung, K. C. Chang, Y. J. Chu, C. C. Chen, J. Y. Ho, C. H. Yu, C. H. | BMC Anesthesiol | 2023 |
Humans |
| Incidence and risk factors for postoperative delirium after head and neck cancer surgery: an updated meta-analysis | Dong, B. Yu, D. Jiang, L. Liu, M. Li, J. | BMC Neurol | 2023 |
Humans |
| Five-year stroke prognosis. Influence of post-stroke delirium and post-stroke dementia on mortality and disability (Research Study - Part of the PROPOLIS Study) | Droś, J. Segiet, N. Początek, G. Klimkowicz-Mrowiec, A. | Neurol Sci | 2023 |
Cognition disorders, Delirium, Dementia, Mortality, Stroke |
| Comparison of continuous sedatives in the burn ICU on delirium and coma | Falksen, J. Young, S. R. Lee, J. A. | J Burn Care Res | 2023 |
burn, coma, delirium, sedation |
| Associations between depression symptom burden and delirium risk: a prospective cohort study | Gaba, A. Li, P. Xi, Z. Gao, C. Ruixue, C. Hu, K. Gao, L. | medRxiv | 2023 |
Altered mental status |
| Delirium and Previous Psychiatric History Independently Predict Poststroke Posttraumatic Stress Disorder | Griffin, T. T. Bhave, V. McNulty, J. Christophe, B. R. Garton, A. L. A. Sander Connolly, E., Jr. | Neurologist | 2023 |
Humans, Female, *Stress Disorders, Post Traumatic/epidemiology/etiology/diagnosis, *Stroke/complications/epidemiology, *Delirium/diagnosis/epidemiology/etiology |
| Incidence of Postoperative Delirium in Cancer Patients After Head and Neck Surgery: A Proportional Meta-analysis | Ho, M. H. Li, P. W. C. Lin, Y. K. Lee, J. J. Lin, C. C. | Otolaryngol Head Neck Surg | 2023 |
cancer, delirium, head and neck cancer, incidence, postoperative, proportional Meta-analysis |
| Triglyceride-glucose index as a valuable predictor for aged 65-years and above in critical delirium patients: evidence from a multi-center study | Huang, X. Cheng, H. Yuan, S. Ling, Y. Tan, S. Tang, Y. Niu, C. Lyu, J. | BMC Geriatr | 2023 |
Humans |
| Reliability and Validity of the Spanish Adaptation of the Stanford Proxy Test for Delirium in 2 Clinical Spanish-Speaking Communities | Infante, S. Behn, A. González, M. Pintor, L. Franco, E. Araya, P. Maldonado, J. R. | J Acad Consult Liaison Psychiatry | 2023 |
Stanford proxy test for delirium, confusion assessment method, delirium, delirium and COVID, factor analysis |
| Association between preoperative neutrophil-lymphocyte ratio, uric acid, and postoperative delirium in elderly patients undergoing degenerative spine surgery | Kato, K. Kinoshita, H. Kumagai, G. Takekawa, D. Nitobe, Y. Asari, T. Wada, K. Kushikata, T. Ishibashi, Y. Hirota, K. | J Anesth | 2023 |
Neuroprotection, Neutrophil–lymphocyte ratio, Postoperative delirium, Spine surgery, Uric acid |
| Preoperative assessment of postoperative delirium: a cross-sectional study of patients and anesthesiologists in Canada | Khaled, M. Youssef, N. Choi, S. Uppal, V. Chui, J. Marcucci, M. Madden, K. Shanthanna, H. | Can J Anaesth | 2023 |
Humans |
| Resting-state prefrontal EEG biomarker in correlation with postoperative delirium in elderly patients | Kim, J. Park, S. Kim, K. N. Ha, Y. Shin, S. J. Cha, W. Lee, K. Y. Choi, J. Koo, B. N. | Front Aging Neurosci | 2023 |
elderly, electroencephalography, median dominant frequency, postoperative complications, postoperative delirium |
| Risk of delirium with antiepileptic drug use: a study based on the Japanese Adverse Drug Event Report database | Kubo, T. Sogawa, R. Tsuruhashi, S. Murakawa-Hirachi, T. Matsuoka, A. Mizoguchi, Y. Monji, A. Shimanoe, C. | Int J Clin Pharm | 2023 |
Humans |
| Optimizing delirium care in the era of Age-Friendly Health System | Kwak, M. J. Inouye, S. K. Fick, D. M. Bonner, A. Fulmer, T. Carter, E. Tabbush, V. Maya, K. Reed, N. Waszynski, C. Oh, E. S. | J Am Geriatr Soc | 2023 |
Age-Friendly Health System, Hospital Elder Life Program, delirium |
| Risk factors for hyperactive delirium after laparoscopic radical gastrectomy under general anesthesia in patients with gastric cancer | Liu, J. Zhong, Q. Tan, H. Zhuo, M. Zhong, M. Cai, T. | Am J Transl Res | 2023 |
Laparoscopic radical gastrectomy, general anesthesia, hyperactive delirium, risk factors |
| Risk factors associated with postoperative delirium in elderly patients undergoing hip surgery | Liu, X. H. Zhang, Q. F. Liu, Y. Lu, Q. W. Wu, J. H. Gao, X. H. Chen, Z. Y. | Front Psychiatry | 2023 |
Pacu |
| The influence of delirium on mortality and length of ICU stay and analysis of risk factors for delirium after liver transplantation | Ma, Y. Li, C. Peng, W. Wan, Q. | ATS Sch | 2023 |
ICU stay |
| Hyperactive delirium during emergency department stay: analysis of risk factors and association with short-term outcomes | Miró, Ò Osorio, G. Alquézar-Arbé, A. Aguiló, S. Fernández, C. Burillo, G. Jacob, J. Llorens, P. Llauger, L. Peláez González, Á Figuera Castro, E. R. Juarez González, R. Blanco Hoffman, M. J. Fernandez Salgado, F. Pablos Pizarro, T. Berenguer Dí | Intern Emerg Med | 2023 |
Benzodiazepines, Delirium, Emergency department, Mortality, Neuroleptics, Outcome |
| Delirium and neuropsychological recovery among emergency general surgery survivors (DANE): study protocol for a randomized controlled trial and collaborative care intervention | Mohanty, S. Holler, E. Ortiz, D. Meagher, A. Perkins, A. Bylund, P. Khan, B. Unverzagt, F. Xu, H. Ingraham, A. Boustani, M. Zarzaur, B. | Trials | 2023 |
Humans |
| A randomized, clinical trial investigating the use of a digital intervention to reduce delirium-associated agitation | Nicholas, M. Wittmann, J. Norena, M. Ornowska, M. Reynolds, S. | NPJ Digit Med | 2023 |
delirium, agitation, digital, RASS |
| Cognitive Deficits in Executive and Language Functions Predict Postoperative Delirium | Olotu, C. Lebherz, L. Ascone, L. Scherwath, A. Kühn, S. Härter, M. Kiefmann, R. | J Cardiothorac Vasc Anesth | 2023 |
Humans |
| Development of post-anesthesia care unit delirium is associated with differences in aperiodic and periodic alpha parameters of the EEG during emergence from general anesthesia - results from a prospective observational cohort study | Ostertag, J. Engelhard, A. Nuttall, R. Aydin, D. Schneider, G. García, P. S. Hinzmann, D. Sleigh, J. W. Kratzer, S. Kreuzer, M. | Anesthesiology | 2023 |
PACU, delirium, EEG, hypnosis, alpha |
| Subsyndromal Delirium in Critically Ill Patients-Cognitive and Functional Long-Term Outcomes | Paulino, M. C. Conceição, C. Silvestre, J. Lopes, M. I. Gonçalves, H. Dias, C. C. Serafim, R. Salluh, J. I. F. Póvoa, P. | J Clin Med | 2023 |
Icu, cognitive dysfunction delirium, long-term outcome, subsyndromal delirium |
| Prevalence of delirium in gastroenterology/hepatology units: A cross-sectional study | Pazouki, R. Hasselblatt, P. Kugler, C. | Z Gastroenterol | 2023 |
Humans |
| Grip Strength is a Predictor for Subsyndromal Delirium Among Older Adults Following Joint Replacement | Qian, J. Shen, X. Gao, X. Sun, Q. | Clin Interv Aging | 2023 |
Aged |
| Prevalence and Risk Factors of Delirium in Patients Admitted to Intensive Care Units: A Multicentric Cross-Sectional Study | Sadaf, F. Saqib, M. Iftikhar, M. Ahmad, A. | Cureus | 2023 |
critical illness, delirium, intensive care units, pakistan, prevalence |
| Perioperative Factors Associated With Postoperative Delirium in Patients Undergoing Noncardiac Surgery: An Individual Patient Data Meta-Analysis | Sadeghirad, B. Dodsworth, B. T. Schmutz Gelsomino, N. Goettel, N. Spence, J. Buchan, T. A. Crandon, H. N. Baneshi, M. R. Pol, R. A. Brattinga, B. Park, U. J. Terashima, M. Banning, L. B. D. Van Leeuwen, B. L. Neerland, B. E. Chuan, A. Martinez, F. T. Van | JAMA Netw Open | 2023 |
Adult |
| Thirty-day mortality among patients with acute delirium in the emergency department | Sanguanwit, P. Ninlamal, S. Prachanukool, T. | Heliyon | 2023 |
30-Day mortality, Delirium, Emergency department, Older-patients |
| Role of hypoxia-inducible factor in postoperative delirium of aged patients: A review | Shen, H. Yang, J. Chen, X. Gao, Y. He, B. | Medicine (Baltimore) | 2023 |
Infant, Newborn, Humans, Aged, *Emergence Delirium, Transcription Factors/metabolism, Hypoxia, Ischemia, *Anesthetics, Hypoxia-Inducible Factor 1, alpha Subunit |
| The efficacy of earplugs and eye masks for delirium severity and sleep quality in patients undergoing coronary artery bypass grafting in cardiac intensive care units: A single-blind, randomised controlled trial | Shorofi, S. A. Dadashian, P. Arbon, P. Moosazadeh, M. | Aust Crit Care | 2023 |
Coronary artery bypass grafting, Delirium, Earplugs, Eye masks, ICU psychosis, Sleep quality |
| Efficacy of haloperidol to decrease the burden of delirium in adult critically ill patients: the EuRIDICE randomized clinical trial | Smit, L. Slooter, A. J. C. Devlin, J. W. Trogrlic, Z. Hunfeld, N. G. M. Osse, R. J. Ponssen, H. H. Brouwers, Ajbw Schoonderbeek, J. F. Simons, K. S. van den Boogaard, M. Lens, J. A. Boer, D. P. Gommers, Dampj Rietdijk, W. J. R. van der Jagt, M. | Crit Care | 2023 |
Adult |
| Efficacy of haloperidol to decrease the burden of delirium in adult critically ill patients: the EuRIDICE randomized clinical trial | Smit, L. Slooter, A. J. C. Devlin, J. W. Trogrlic, Z. Hunfeld, N. G. M. Osse, R. J. Ponssen, H. H. Brouwers, Ajbw Schoonderbeek, J. F. Simons, K. S. van den Boogaard, M. Lens, J. A. Boer, D. P. Gommers, Dampj Rietdijk, W. J. R. van der Jagt, M. | Crit Care | 2023 |
Adult |
| Effectiveness of a Multi-component Delirium Prevention Program Implemented on General Medicine Hospital Units: an Interrupted Time Series Analysis | Versloot, J. Minotti, S. C. Amer, S. Ali, A. Ma, J. Peters, M. L. Saab, H. Tang, T. Kerr, J. Reid, R. | J Gen Intern Med | 2023 |
Adult, Humans, Aged, Aged, 80 and over, Interrupted Time Series Analysis, Retrospective Studies, *Delirium/diagnosis/epidemiology/prevention & control, Hospitals, Community, Ontario, Hospital Units, delirium prevention, delirium program, inpatients, internal medicine |
| Delirium During Critical Illness and Subsequent Change of Treatment in Patients With Cancer: A Mediation Analysis | Vizzacchi, B. A. Dettino, A. L. A. Besen, Bamp Caruso, P. Nassar, A. P., Jr. | Crit Care Med | 2023 |
IUC, delirium, cohort, cancer, CAM |
| Efficacy and moderators of prevention and treatment of delirium with melatonin receptor agonists: A systematic review and meta-analysis of randomized controlled trials | Wada, M. Yasuda, H. Nakajima, S. Etani, T. Miura, A. Asada, S. Yoshida, K. Noda, Y. Takeuchi, H. | Gen Hosp Psychiatry | 2023 |
Delirium |
| Intraoperative body temperature and emergence delirium in elderly patients after non-cardiac surgery: A secondary analysis of a prospective observational study | Wang, G. He, S. Yu, M. Zhang, Y. Mu, D. Wang, D. | Chin Med J (Engl) | 2023 |
Humans |
| Relationship between preoperative neutrophil-to-lymphocyte ratio and postoperative delirium: The PNDABLE and the PNDRFAP cohort studies | Wu, X. Chi, F. Wang, B. Liu, S. Wang, F. Wang, J. Tang, X. Bi, Y. Lin, X. Li, J. | Brain Behav | 2023 |
Alzheimer-related biomarkers |
| Risk Factors for Delirium Superimposed on Dementia in Elderly Patients in Comprehensive Ward | Xiao, Q. Zhang, S. Li, C. Zhu, Y. | Am J Alzheimers Dis Other Demen | 2023 |
Humans |
| Effect of postoperative delirium after cardiovascular surgery on 5-year mortality | Yokoyama, C. Yoshitnai, K. Ogata, S. Fukushima, S. Matsuda, H. | JA Clin Rep | 2023 |
5-year mortality, Cardiopulmonary bypass, Cardiovascular surgery, Postoperative delirium |
| Association Between the Use of Midazolam During Cardiac Anesthesia and the Incidence of Postoperative Delirium: A Retrospective Cohort Study Using a Nationwide Database | Yoshimura, M. Hidaka, Y. Morimoto, Y. | J Cardiothorac Vasc Anesth | 2023 |
Humans, *Emergence Delirium/epidemiology, Midazolam/adverse effects, Retrospective Studies, Incidence, Postoperative Nausea and, Vomiting/chemically induced/epidemiology, *Anesthesia, Cardiac Procedures, Postoperative, Complications/chemically induced/epidemiology, Diagnosis Procedure, Combination data, cardiac surgery, midazolam, postoperative delirium, stabilized inverse probability of treatment |
| Associations of Delirium to Posthospital Outcomes After Acute Stroke: A Scoping Review | Young, B. C. Rhoten, B. A. | J Neurosci Nurs | 2023 |
Adult, Humans, Adolescent, *Dexmedetomidine/therapeutic use, Palliative Care, *Pain, Intractable/drug therapy/chemically induced, Hypnotics and, Sedatives/therapeutic use, Retrospective Studies, *Delirium/drug therapy, Intensive Care Units |
| Dexmedetomidine use for patients in palliative care with intractable pain and delirium: A retrospective study | Yu, S. Y. Schellenberg, J. Alleyne, A. | PLoS One | 2023 |
Adult, Humans, Adolescent, *Dexmedetomidine/therapeutic use, Palliative Care, *Pain, Intractable/drug therapy/chemically induced, Hypnotics and, Sedatives/therapeutic use, Retrospective Studies, *Delirium/drug therapy, Intensive Care Units |
| Validity and predictability of the confusion assessment method for the intensive care unit for delirium among critically ill patients in the intensive care unit: A systematic review and meta-analysis | Zhang, Y. Diao, D. Zhang, H. Gao, Y. | Nurs Crit Care | 2023 |
Cam-icu, critical, delirium, intensive care unit |
| Impact of nursing interventions on discharge disposition in patients with postoperative delirium | Zhao, Y. Quon, A. Luke, K. Tivis, L. J. | Nursing | 2023 |
Humans, Aged, Patient Discharge, Retrospective Studies, *Emergence Delirium, *Hypoalbuminemia, Hospitalization |
| Causal relationships between delirium and Alzheimer's disease: a bidirectional two-sample Mendelian randomization study | Zheng, J. Du, X. Yang, L. Fu, H. | Eur J Med Res | 2023 |
Humans, *Alzheimer Disease/genetics, Genome-Wide Association Study, Mendelian Randomization Analysis, Risk Factors, Nonoxynol, Alzheimer’s disease, Causal relationships, Delirium, European, Mendelian randomization |
| Circadian rhythm disturbance and delirium in ICU patients: a prospective cohort study | Li, J. Cai, S. Liu, X. Mei, J. Pan, W. Zhong, M. Zhang, Y. | Medicine (Baltimore) | 2023 |
United States, Humans, *Hydrocortisone, *Melatonin, Prospective Studies, Circadian Rhythm, Intensive Care Units, Cortisol, Delirium, Melatonin |
| Amantadine-associated delirium in patients with maintenance dialysis: Insomnia-associated recovery and uneven seasonal distribution | Li, J. Si, B. Chao, J. He, J. | Medicine (Baltimore) | 2023 |
Humans, Renal Dialysis, Retrospective Studies, Seasons, *Sleep Initiation and Maintenance Disorders/drug therapy, Amantadine/adverse effects, *Delirium/chemically induced/epidemiology |