Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
The effects of early femoral nerve block intervention on preoperative pain management and incidence of postoperative delirium geriatric patients undergoing trochanteric femur fracture surgery: A randomized controlled trial
Authors
Uysal, A. I. Altiparmak, B. Yasar, E. Turan, M. Canbek, U. Yilmaz, N. Gumus Demirbilek, S.
Year
2020
Journal
Ulus Travma Acil Cerrahi Derg
Abstract

BACKGROUND: Hip fracture is a common clinical problem which causes severe pain in geriatric patients. However, severe pain following fracture may bring on mental disorders and delirium. A neuroinflammatory response with IL-6 and IL-8 has been shown to be associated with the pathophysiology of delirium. In this study, our primary hypothesis is that preoperative femoral nerve block (FNB) intervention in geriatric patients will more effectively attenuate pain following trochanteric femur fracture than the preoperative paracetamol application. Our secondary hypothesis is that interleukin levels (IL-6, IL-8) in cerebrospinal fluid (CSF) will be lower in the femoral nerve block group than the paracetamol group. Our tertiary hypothesis is that the incidence of postoperative delirium will be lower in the femoral nerve block group. METHODS: The patients over 65 years of age with ASA status II-IV and admitted to the Emergency Service for femur fracture were included in this study. Recommendations of the ‘delirium prevention table’ were applied to all of the patients at arrival. In the first group, 15 mg/kg paracetamol was administered intravenously every eight hours. In the second group, femoral nerve blockage was performed, and a catheter was placed. Then, 0.5 mL/kg bupivacaine 0.25% was applied every eight hours. In both groups, pain scores four hours after interventions were recorded. All patients were operated within 48 hours under spinal anesthesia. During spinal anesthesia, 2 mL of CSF samples were taken from all patients for analysis of IL-6 and IL-8 cytokines, and pain scores during positioning were recorded. RESULTS: VAS scores four hours after the first preoperative pain treatment and during the positioning for regional anesthesia were significantly lower in the femoral nerve block group. IL-8 levels are significantly lower in the femoral nerve block group but not in IL-6 levels. The incidence of delirium was less in the femoral nerve block group, but the difference was not statistically significant. CONCLUSION: The femoral nerve block was more effective in preoperative pain management of trochanteric femur fracture and preventing pain during regional anesthesia application. The mean IL-8 level was lower in the femoral nerve block group when compared to the paracetamol group. There is no difference in the postoperative delirium incidence between groups.

PMID

31942744

Keywords
Page(s)
109-114
Issue
1

Search:
Total Records Found: 6272, showing 100 per page
TitleAuthorsJournalYearKeywords
Dementia Development during Long-Term Follow-Up after Surgical Aortic Valve Replacement with a Biological Prosthesis in a Geriatric Population Deblier, I. Dossche, K. Vanermen, A. Mistiaen, W. J Cardiovasc Dev Dis 2024

dementia
predictors
surgical aortic valve replacement

A Comparison of Efficacy between Low-dose Dexmedetomidine and Propofol for Prophylaxis of Postoperative Delirium in Elderly Patients Undergoing Hip Fracture Surgery: A Randomized Controlled Trial Ekkapat, G. Kampitak, W. Theerasuwipakorn, N. Kittipongpattana, J. Engsusophon, P. Phannajit, J. Chokengarmwong, N. Indian J Crit Care Med 2024

Dexmedetomidine
Geriatric anesthesia
Hip fracture surgery
Postoperative delirium
Propofol

Development and validation of a new drug-focused predictive risk score for postoperative delirium in orthopaedic and trauma surgery patients Geßele, C. Saller, T. Smolka, V. Dimitriadis, K. Amann, U. Strobach, D. BMC Geriatr 2024

Humans
Female
Male
Aged
Retrospective Studies
*Delirium/diagnosis
*Postoperative Complications/diagnosis/prevention & control/epidemiology
Risk Factors
*Orthopedic Procedures/adverse effects/methods
Risk Assessment/methods
Middle Aged
Wounds and Injuries/surgery
Aged, 80 and over
Medication Reconciliation/methods
Acute Care Surgery
Geriatrics
Medication Safety
Postoperative delirium
Screening tools

Preoperative cognitive performance and its association with postoperative complications in vascular surgery patients: A prospective study Goodijk, D. Banning, L. B. D. Te Velde-Keyzer, C. A. van Munster, B. C. Bakker, S. J. L. van Leeuwen, B. L. Zeebregts, C. J. Pol, R. A. Am J Surg 2024

Cognition
Cognitive impairment
Postoperative complications
Vascular surgical procedure

Prognostic Nutritional Index and the Risk of Postoperative Complications After Spine Surgery: A Meta-Analysis Guo, H. Yang, L. Liu, J. Yu, X. Chen, L. Huang, Y. World Neurosurg 2024

Humans
*Postoperative Complications/epidemiology/etiology
Prognosis
*Nutrition Assessment
Malnutrition
Risk Factors
Spine/surgery
Postoperative complications
Postoperative delirium
Prognostic nutritional index
Spine surgery
Surgical site infection

Risk stratification and predictive modeling of postoperative delirium in chronic subdural hematoma Yang, X. Regmi, M. Wang, Y. Liu, W. Dai, Y. Liu, S. Lin, G. Yang, J. Ye, J. Yang, C. Neurosurg Rev 2024

Humans
Male
Female
Aged
*Hematoma, Subdural, Chronic/complications
*Emergence Delirium/complications
Retrospective Studies
Risk Factors
Risk Assessment
Electrolytes
Chronic subdural hematoma
Postoperative delirium

Association between increased systemic immune-inflammation index and postoperative delirium in older intertrochanteric fracture patients Yan, X. Huang, J. Chen, X. Lin, M. J Orthop Surg Res 2024

Humans
Aged
*Emergence Delirium
Retrospective Studies
*Hip Fractures/surgery
Nomograms
Inflammation
Older intertrochanteric fracture patients
Postoperative delirium
Systemic immune-inflammation index

Intravenous infusion of dexmedetomidine during the surgery to prevent postoperative delirium and postoperative cognitive dysfunction undergoing non-cardiac surgery: a meta-analysis of randomized controlled trials Wang, D. Liu, Z. Zhang, W. Zu, G. Tao, H. Bi, C. Eur J Med Res 2024

Humans
Bradycardia/epidemiology
*Dexmedetomidine/therapeutic use
*Emergence Delirium/epidemiology/prevention & control
*Hypotension/epidemiology
Infusions, Intravenous
*Postoperative Cognitive Complications/prevention & control
Postoperative Complications/prevention & control/epidemiology
Quality of Life
Randomized Controlled Trials as Topic
Dexmedetomidine
Non-cardiac surgery and non-neurosurgery
Postoperative cognitive dysfunction
Postoperative delirium

Triglyceride-glucose index predicts postoperative delirium in elderly patients with type 2 diabetes mellitus: a retrospective cohort study Sun, M. Liu, M. Zhang, F. Sang, L. Song, Y. Li, P. Liu, S. Yang, H. Ma, L. Cao, J. Mi, W. Ma, Y. Lipids Health Dis 2024

Aged
Female
Male
Humans
*Diabetes Mellitus, Type 2/complications
*Emergence Delirium
Retrospective Studies
Glucose
Triglycerides
Biomarkers
Blood Glucose
Risk Factors
Elderly surgical patients
Insulin resistance
Postoperative delirium
Triglyceride glucose index
Type 2 diabetes mellitus

Electroencephalogram Biomarkers from Anesthesia Induction to Identify Vulnerable Patients at Risk for Postoperative Delirium Pollak, M. Leroy, S. Röhr, V. Brown, E. N. Spies, C. Koch, S. Anesthesiology 2024

Humans
Aged
*Emergence Delirium/etiology
*Delirium/diagnosis
Prospective Studies
Electroencephalography
Anesthesia, General/adverse effects
Unconsciousness
Postoperative Complications/diagnosis/epidemiology/etiology

Mesial temporal atrophy in preoperative MRI rather than steep Trendelenburg position is associated with postoperative delirium in patients undergoing a major urologic surgery Park, J. H. Park, I. Yoon, J. Sim, Y. Kim, J. Lee, S. K. Joo, B. Int Urol Nephrol 2024

Male
Humans
Female
*Emergence Delirium/complications
Retrospective Studies
*Delirium/etiology/complications
Head-Down Tilt
Magnetic Resonance Imaging
Atrophy/complications
Postoperative Complications/epidemiology/etiology
Risk Factors
Delirium
Emergence delirium
Urologic surgical procedures

Comparison of Remimazolam and Propofol on Postoperative Delirium in Elderly Patients Undergoing Radical Resection of Colon Cancer: A Single-Center Prospective Randomized Controlled Study Liu, T. Zhao, H. Zhao, X. Qu, M. Med Sci Monit 2024

Humans
Aged
*Propofol
*Emergence Delirium/chemically induced
Prospective Studies
*Delirium/etiology/drug therapy
Vomiting/chemically induced
*Colonic Neoplasms/surgery/drug therapy
*Respiratory Insufficiency
Nausea/chemically induced
Hypoxia/drug therapy
*Benzodiazepines

Dynamic Delirium Prediction in the Intensive Care Unit using Machine Learning on Electronic Health Records Contreras, M. Silva, B. Shickel, B. Bandyopadhyay, S. Guan, Z. Ren, Y. Ozrazgat-Baslanti, T. Khezeli, K. Bihorac, A. Rashidi, P. IEEE EMBS Int Conf Biomed Health Inform 2023

Delirium

ICU

Machine learning system

Delirium Prediction

The Role of Delirium on Short- and Long-Term Postoperative Outcomes Following Major Gastrointestinal Surgery for Cancer Katayama, E. S. Stecko, H. Woldesenbet, S. Khalil, M. Munir, M. M. Endo, Y. Tsilimigras, D. Pawlik, T. M. Ann Surg Oncol 2024

Delirium

Digestive tract surgery

Surgical outcomes

Postoperative delirium

Expenditures

Long-term outcomes after treatment of delirium during critical illness with antipsychotics (MIND-USA): a randomised, placebo-controlled, phase 3 trial Mart, M. F. Boehm, L. M. Kiehl, A. L. Gong, M. N. Malhotra, A. Owens, R. L. Khan, B. A. Pisani, M. A. Schmidt, G. A. Hite, R. D. Exline, M. C. Carson, S. S. Hough, C. L. Rock, P. Douglas, I. S. Feinstein, D. J. Hyzy, R. C. Schweickert, W. D. Bowton, D. L. Lancet Respir Med 2024

Delirium

Critical illness

Antipsychotics

Long-term cognitive impairment

Haloperidol

Ziprasidone

Incidence and assessment of delirium following open cardiac surgery; A systematic review and meta-analysis Petersson, N. B. Hansen, M. H. Hjelmborg, J. V. B. Instenes, I. Christoffersen, A. S. Larsen, K. L. Schmidt, H. Riber, L. P. S. Norekvål, T. M. Borregaard, B. Eur J Cardiovasc Nurs 2024

Open Cardiac Surgery

Delirium

Systematic Review

CAM

CAM-ICU

Delirium assessment tools

Significance Analysis of the Improvement in Postoperative Recovery of Cardiac Surgery Patients Based on the Graded Management Established Using the Delirium Prediction Model Zhang, H. Wang, Q. Feng, P. Altern Ther Health Med 2024

Cardiac Surgery

Delirium Prediction

Delirium

ICU Delirium

Type A aortic coarctation

Postoperative Delirium and the Older Adult: Untangling the Confusion Thedim, M. Vacas, S. J Neurosurg Anesthesiol 2024

aging, anesthesia, delirium, inflammation, sleep

Efficacy and safety of music therapy for the treatment of anxiety and delirium in ICU patients: a meta-analysis and systematic review of randomized controlled trials Xiao, M. Gong, C. Mai, M. Huang, M. Xiong, A. Liu, H. Jiang, R. Minerva Anestesiol 2024

Music therapy; Intensive care units; Anxiety; Delirium; Meta-analysis

Aripiprazole for treating delirium: A systematic review-Is it a valid yet understudied treatment? Maddalena, S. Magistri, C. Mellini, C. Sarli, G. J Psychopharmacol 2024

Haloperidol
antipsychotics
confusional state
extrapyramidal side
geriatric

Delirium screening in the emergency department: evaluation and intervention Meged-Book, T. Frenkel, R. Nikonov, A. Zeldetz, V. Kosto, A. Schwarzfuchs, D. Freud, T. Press, Y. Isr J Health Policy Res 2024

Humans
Aged
*Delirium/diagnosis/epidemiology
Prospective Studies
Israel
Hospitalization
Emergency Service, Hospital
Delirium
Emergency department
Older adults

A Toolkit for Delirium Identification and Promoting Partnerships Between Carers and Nurses: A Pilot Pre-Post Feasibility Study Aggar, C. Craswell, A. Bail, K. Compton, R. M. Hughes, M. Sorwar, G. Baker, J. Greenhill, J. Shinners, L. Nichols, B. Langheim, R. Wallis, A. Bowen, K. Bridgett, H. J Gen Intern Med 2024

caregiving
carers
delirium
family

The role of heart rate variability in predicting delirium: A systematic review and meta-analysis Amit Patel, K. Sethi, A. Al Azazi, E. McClurg, C. Chowdhury, T. J Clin Neurosci 2024

Delirium
Heart rate variability
Intensive care unit
Prediction
Surgery

Efficacy of melatonin in decreasing the incidence of delirium in critically ill adults: a randomized controlled trial Bandyopadhyay, A. Yaddanapudi, L. N. Saini, V. Sahni, N. Grover, S. Puri, S. Ashok, V. Crit Care Sci 2024

Humans
*Melatonin/administration & dosage/therapeutic use
*Delirium/prevention & control/epidemiology/drug therapy
*Critical Illness
Male
Female
Middle Aged
Incidence
*Intensive Care Units
Length of Stay
Aged
Respiration, Artificial/adverse effects
Adult

Assessment and report of individual symptoms in studies of delirium in postoperative populations: a systematic review Bowman, E. M. L. Sweeney, A. M. McAuley, D. F. Cardwell, C. Kane, J. Badawi, N. Jahan, N. Iqbal, H. K. Mitchell, C. Ballantyne, J. A. Cunningham, E. L. Age Ageing 2024

Humans
*Delirium/diagnosis/etiology/prevention & control
Psychomotor Agitation
attention
cognition
delirium
older people
postoperative delirium
symptoms
systematic review

Systemic inflammation and delirium during critical illness Brummel, N. E. Hughes, C. G. McNeil, J. B. Pandharipande, P. P. Thompson, J. L. Orun, O. M. Raman, R. Ware, L. B. Bernard, G. R. Harrison, F. E. Ely, E. W. Girard, T. D. Intensive Care Med 2024

Coma
Critical illness
Delirium
Inflammation

Hospitalized Patients With Delirium and 28-Day Unplanned Hospital Readmissions: A Longitudinal Retrospective Cohort Study Butala, A. Gilbert, J. M. Griffiths, A. A. Lim, W. K. J Am Med Dir Assoc 2024

Delirium
Hospitalization
Nursing homes
Readmission
Unplanned

Validity and reliability of the Turkish version of the Informant Assessment of Geriatric Delirium Scale Celik, B. Bilik, O. Koçbilek, Z. D. Damar, H. T. Öz, D. Denizmen, Z. Ideggyogy Sz 2024

Aged
Humans
Reproducibility of Results
*Geriatric Assessment
Sensitivity and Specificity
ROC Curve
*Delirium/diagnosis/etiology
Surveys and Questionnaires
caregiver
delírium
geriatry
patient

Can admission Braden skin score predict delirium in older adults in the intensive care unit? Results from a multicenter study Cheng, H. Huang, X. Yuan, S. Song, S. Tang, Y. Ling, Y. Tan, S. Wang, Z. Zhou, F. Lyu, J. J Clin Nurs 2024

Humans
*Delirium/diagnosis/epidemiology/nursing
Female
*Intensive Care Units/statistics & numerical data
Aged
Male
Aged, 80 and over
Pressure Ulcer/epidemiology
Cohort Studies
Risk Assessment/methods
Risk Factors
Braden skin score
delirium
electronic medical records
frailty
intensive care unit
older adults

Malnutrition-Related Health Outcomes in Older Adults with Hip Fractures: A Systematic Review and Meta-Analysis Chiavarini, M. Ricciotti, G. M. Genga, A. Faggi, M. I. Rinaldi, A. Toscano, O. D. D'Errico, M. M. Barbadoro, P. Nutrients 2024

Humans
Aged
*Hip Fractures/complications/surgery
*Malnutrition/complications
Nutritional Status
Outcome Assessment, Health Care
*Delirium
elderly
hip fracture
malnutrition
mobility limitation
mortality
older adults

Organizational Context and Facilitation Interactions on Delirium Risk in Long-Term Care: A Cross-Sectional Study Choroschun, K. Estabrooks, C. A. Duan, Y. Chamberlain, S. Shrestha, S. Cummings, G. G. Iaconi, A. Norton, P. G. Song, Y. Hoben, M. J Am Med Dir Assoc 2024

Organizational context
health care research
nurse staffing
quality improvement interventions
quality in long-term care

Delirium and delirium severity screening in the intensive care-correspondence of screenings tools Collet, M. O. Nielsen, A. H. Larsen, L. K. Laerkner, E. Jensen, J. F. Mortensen, C. B. Lehmkuhl, L. Thorn, L. Rossen, B. S. Nielsen, T. A. Laursen, E. Shiv, L. H. Villumsen, M. Rahr, M. N. Svenningsen, H. Aust Crit Care 2024

Adult
Aged
Female
Humans
Male
Critical Care/methods
*Delirium/diagnosis
Hospitalization
Intensive Care Units
Prospective Studies
Critically ill
Delirium
Delirium severity
Intensive care unit
Screening method

A joint frailty model for recurrent and competing terminal events: Application to delirium in the ICU Etzkorn, L. H. Coënt, Q. L. van den Boogaard, M. Rondeau, V. Colantuoni, E. Stat Med 2024

competing events
delirium
frailty
joint models
recurrent events

Nomogram for predicting the risk of postoperative delirium in elderly patients undergoing orthopedic surgery Fan, Y. Yang, T. Liu, Y. Gan, H. Li, X. Luo, Y. Yang, X. Pang, Q. Perioper Med (Lond) 2024

Elderly patients
Orthopedic surgery
Postoperative delirium
Predictive models

The Association of Plasma Leptin, Soluble Leptin Receptor and Total and High-Molecular Weight Adiponectin With the Risk of Perioperative Neurocognitive Disorders Feinkohl, I. Janke, J. Slooter, A. J. C. Winterer, G. Spies, C. Pischon, T. Am J Geriatr Psychiatry 2024

Adiponectin
epidemiology
leptin
postoperative cognitive dysfunction
postoperative delirium

A novel nomogram for the prediction of subsyndromal delirium in patients in intensive care units: A prospective, nested case-controlled study Gao, Y. Gan, X. Int J Nurs Stud 2024

Delirium
Intensive care units
Nomogram
Risk prediction
Subsyndromal delirium

Association Between Preoperative Sleep Disturbance and Postoperative Delirium in Elderly: A Retrospective Cohort Study Guo, H. Li, L. H. Lv, X. H. Su, F. Z. Chen, J. Xiao, F. Shi, M. Xie, Y. B. Nat Sci Sleep 2024

anesthesia
postoperative delirium
postoperative pain
postoperative sleep quality
sleep disturbances

Validation to Spanish of nursing assessment scale for early diagnosis of delirium - Nu-DESC Henao Castaño Á, M. Lozano González, L. M. Gómez Tovar, L. O. Invest Educ Enferm 2023

Adult
Humans
*Delirium/diagnosis
Reproducibility of Results
Nursing Assessment
Intensive Care Units
Early Diagnosis
delirium
psychometrics
validation study

Predictive modeling for postoperative delirium in elderly patients with abdominal malignancies using synthetic minority oversampling technique Hu, W. J. Bai, G. Wang, Y. Hong, D. M. Jiang, J. H. Li, J. X. Hua, Y. Wang, X. Y. Chen, Y. World J Gastrointest Oncol 2024

Abdominal cancer
Elderly patients
Postoperative delirium
Predictive modeling
Surgical outcomes
Synthetic minority oversampling technique

Reliability and Validity of the Spanish Adaptation of the Stanford Proxy Test for Delirium in Two Clinical Spanish-Speaking Communities Infante, S. Behn, A. González, M. Pintor, L. Franco, E. Araya, P. Maldonado, J. R. J Acad Consult Liaison Psychiatry 2024

Humans
Adolescent
Adult
*Delirium/diagnosis/etiology
Reproducibility of Results
Cross-Sectional Studies
Sensitivity and Specificity
Intensive Care Units
Stanford proxy test for delirium
confusion assessment method
delirium
delirium and COVID
factor analysis

Detection of delirium in older patients-A point prevalence study in surgical and non-surgical hospital wards Instenes, I. Eide, L. S. P. Andersen, H. Fålun, N. Pettersen, T. Ranhoff, A. H. Rudolph, J. L. Steihaug, O. M. Wentzel-Larsen, T. Norekvål, T. M. Scand J Caring Sci 2024

4at
acute hospital care
delirium
delirium motor subtype scale
delirium screening
older patients

The impact of delirium on clinical and functional outcomes in hospitalized patients with acute coronary syndrome Ioanna, D. Evangelos, F. John, S. Aikaterini, T. Ioannis, V. Dimitrios, P. Maria, S. Nurs Crit Care 2024

acute coronary syndrome
cardiac intensive care unit
delirium
elderly
mortality

Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): Feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care Jackson, G. P. Jackson, C. E. Boland, J. W. Featherstone, I. Huang, C. Ogden, M. Sartain, K. Siddiqi, N. Twiddy, M. Pearson, M. Johnson, M. J. Palliat Med 2024

Humans
*Hospices
Feasibility Studies
*Delirium
Palliative Care
Hospitalization
Delirium
feasibility
guideline adherence
hospices
implementation

Diffuse optical tomography for mapping cerebral hemodynamics and functional connectivity in delirium Jiang, S. Huang, J. Yang, H. Czuma, R. Farley, L. Cohen-Oram, A. Hartney, K. Chechotka, K. Kozel, F. A. Jiang, H. Alzheimers Dement 2024

acute brain failure
delirium
diffuse optical tomography
encephalopathy
near‐infrared light
optical imaging

Cognitive Training for Reduction of Delirium in Patients Undergoing Cardiac Surgery: A Randomized Clinical Trial Jiang, Y. Xie, Y. Fang, P. Shang, Z. Chen, L. Zhou, J. Yang, C. Zhu, W. Hao, X. Ding, J. Yin, P. Wang, Z. Cao, M. Zhang, Y. Tan, Q. Cheng, D. Kong, S. Lu, X. Liu, X. Sessler, D. I. JAMA Netw Open 2024

Humans
Male
Female
Middle Aged
Aged
*Delirium/prevention & control/epidemiology/etiology
Single-Blind Method
Prospective Studies
*Postoperative Complications/prevention & control/epidemiology
*Coronary Artery Bypass/adverse effects
China/epidemiology
Cognitive Behavioral Therapy/methods
Cognitive Training

Physical activity may a probably protective factor for postoperative delirium: the PNDABLE study Kong, J. Lin, X. Wang, B. Xu, S. Wang, Y. Hua, S. Gong, H. Dong, R. Lin, Y. Li, C. Bi, Y. Front Aging Neurosci 2024

Alzheimer-related biomarkers
cerebrospinal fluid
physical activity
postoperative complications
postoperative delirium

Effects of Exercise Intervention for the Management of Delirium in Hospitalized Older Adults: A Randomized Clinical Trial Lozano-Vicario, L. Zambom-Ferraresi, F. Zambom-Ferraresi, F. L. Sáez de Asteasu M Galbete-Jiménez, A. Muñoz-Vázquez Á, J. Cedeno-Veloz, B. A. De la Casa-Marín, A. Ollo-Martínez, I. Fernández-Irigoyen, J. Santamaría, E. San Miguel Elcano, R. Ortiz J Am Med Dir Assoc 2024

delirium
hospitalization
physical exercise

The association between the fibrinogen-to-albumin ratio and delirium after deep brain stimulation surgery in Parkinson's disease Lu, W. Wang, H. Lin, S. Chang, X. Wang, J. Wu, X. Yu, X. Front Med (Lausanne) 2024

Parkinson’s disease
deep brain stimulation
fibrinogen-to-albumin ratio
general anesthesia
postoperative delirium

The Application Value of Esketamine and Dexmedetomidine in Preventing Postoperative Delirium and Hyperalgesia in Elderly Patients with Thoracic Anesthesia Lu, Y. Yin, G. Jin, C. Gu, K. Bao, D. Xu, W. Yang, Z. Altern Ther Health Med 2024

Humans
*Dexmedetomidine/therapeutic use/administration & dosage
*Ketamine/therapeutic use/administration & dosage
Aged
Female
Male
*Hyperalgesia/prevention & control
Thoracic Surgical Procedures/adverse effects
Postoperative Complications/prevention & control
Aged, 80 and over
Delirium/prevention & control
Hypnotics and Sedatives/administration & dosage/therapeutic use
Middle Aged

A Molecular Framework for Delirium Lyman, K. A. Neurohospitalist 2024

attention
cyclic adenosine monophosphate
delirium
dexmedetomidine
dorsolateral prefrontal cortex
guanfacine
hyperpolarization-activated cyclic nucleotide–gated channels
tetratricopeptide-repeat containing, Rab8b-interacting protein
working memory

Evaluation of Delirium Among Elders in the Emergency Department: A Cross-Sectional Study Marcomini, I. Pisoni, L. Mellino, A. Labaran, R. Milani, L. Dimens Crit Care Nurs 2024

Humans
Aged
*Delirium/diagnosis/epidemiology
Cross-Sectional Studies
Prospective Studies
Hospitalization
Emergency Service, Hospital

A Mediation Analysis Examining High Risk, Anticholinergic Medication Use, Delirium, and Dementia After Major Surgery Mohanty, S. Lindroth, H. Timsina, L. Holler, E. Jenkins, P. Ortiz, D. Hur, J. Gillio, A. Zarzaur, B. Boustani, M. J Surg Res 2024

Anticholinergics
Dementia
Geriatrics
Postoperative delirium
Surgery

Comparing the delirium objective structured clinical examination (OSCE) education package to standard education for post-registration nurses: A randomised controlled trial Montgomery, A. Smerdely, P. Hickman, L. Traynor, V. Nurse Educ Today 2024

Delirium
Education
Knowledge
Nurses
Randomised Controlled Trail

Postoperative cognitive dysfunction: Review of pathophysiology, diagnostics and preventive strategies Nešković, N. Budrovac, D. Kristek, G. Kovačić, B. Škiljić, S. J Perioper Pract 2024

Neuroinflammation
Postoperative cognitive dysfunction
Prevention
Risk factors

Prognostic implications of delirium after Left Ventricular Assist Device (LVAD) implantation: A retrospective study Noufi, P. Anderson, K. M. Crowell, N. White, Y. Molina, E. Rao, S. D. Groninger, H. J Acad Consult Liaison Psychiatry 2024

Delirium
Lvad
morbidity
mortality

Sex Differences in Delirium after Coronary Artery Bypass Graft Surgery and Perioperative Neuropsychiatric Conditions: A Secondary Analysis of a Cohort Study Oldham, M. A. Kukla, B. Walsh, P. Lee, H. B. J Geriatr Psychiatry Neurol 2024

coronary artery bypass graft surgery outcomes
depression
neuropsychiatric conditions
postoperative delirium
sex differences

Incidence of confusional syndrome (delirium) in a Latin American university hospital Oviedo Lugo, G. F. García Martínez, P. A. Duarte Osorio, A. Rincón, C. J. López, A. Chavarría, R. Pineda Betancur, C. García Gil, N. Duarte Ariza, M. N. Patiño Trejos, J. A. Insignares, J. S. Gómez-Restrepo, C. Rev Colomb Psiquiatr (Engl Ed) 2024

Cam
Cam icu
Delirium
Delirium assessment
Delirium subtypes
Geriatric Unit
Incidence

Postoperative cognitive disorders and delirium in gynecologic surgery: Which surgery and anesthetic techniques to use to reduce the risk? Pecorella, G. De Rosa, F. Licchelli, M. Panese, G. Carugno, J. T. Morciano, A. Tinelli, A. Int J Gynaecol Obstet 2024

anesthesia
blood loss
duration of surgery
gynecologic surgery
pneumoperitoneum
postoperative cognitive disorders
postoperative delirium
surgical complications

Serum NFL and tau, but not serum UCHL-1 and GFAP or CSF SNAP-25, NPTX2, or sTREM2, correlate with delirium in a 3-year retrospective analysis Piel, J. H. A. Bargemann, L. Leypoldt, F. Wandinger, K. P. Dargvainiene, J. Front Neurol 2024

Alzheimer’s disease
delirium
glial fibrillary acidic protein
neurofilament light chain
neuronal pentraxin 2
single-molecule array
soluble triggering receptor expressed on myeloid cells 2
tau protein

Age-stratified comorbid and pharmacologic analysis of patients with glioblastoma Rabin, E. E. Huang, J. Kim, M. Mozny, A. Lauing, K. L. Penco-Campillo, M. Zhai, L. Bommi, P. Mi, X. Power, E. A. Prabhu, V. C. Anderson, D. E. Barton, K. P. Walunas, T. L. Schiltz, G. E. Amidei, C. Sanchez-Gomez, P. Thakkar, J. P. Lukas, R. V. Wainwright, Brain Behav Immun Health 2024

Confusion
Delirium
Dementia
Elderly
Glioma

Unraveling the Predictors for Delirium and ICU Stay Duration in Patients with Heart Failure and Reduced Ejection Fraction (HFrEF) Undergoing Coronary Artery Bypass Grafting-A Multicentric Analysis Rustenbach, C. J. Reichert, S. Berger, R. Schano, J. Nemeth, A. Haeberle, H. Charotte, C. Caldonazo, T. Saqer, I. Saha, S. Schnackenburg, P. Djordjevic, I. Krasivskyi, I. Wendt, S. Serna-Higuita, L. M. Doenst, T. Hagl, C. Wahlers, T. Schlensak, C. Sandova Biomedicines 2024

Cabg
HFrEF
ICU stay
Opcab
heart failure
postoperative delirium

Validation of the Delirium Observation Screening Scale in long-term care facilities in Flanders Sabbe, K. van der Mast, R. Dilles, T. Van Rompaey, B. Geriatr Gerontol Int 2024

delirium
long‐term care facilities
nursing homes

Effect of hospital elder life program on the incidence of delirium: A systematic review and meta-analysis of clinical trials Shen, H. Liu, X. Wu, L. Jia, J. Jin, X. Geriatr Nurs 2024

Humans
Aged
*Delirium/epidemiology/prevention & control/drug therapy
Incidence
Length of Stay
Hospitals
Delirium
Hospital elder life program
Meta-analysis

Impact of Delirium Onset and Duration on Mortality in Patients With Cancer Admitted to the ICU Tao, J. Seier, K. P. Chawla, S. Tan, K. S. Wheeler, A. Sanzone, J. Marasigan-Stone, C. B. Simondac, J. S. Pascual, A. V. Kostelecky, N. T. Voigt, L. P. J Intensive Care Med 2024

ICU outcomes
cancer
delirium
hospital mortality

Interventions to prevent and treat delirium: An umbrella review of randomized controlled trials Veronese, N. Solimando, L. Bolzetta, F. Maggi, S. Fiedorowicz, J. G. Gupta, A. Fabiano, N. Wong, S. Boyer, L. Fond, G. Dragioti, E. Dominguez, L. J. Barbagallo, M. Romagnoli, S. Bellelli, G. Solmi, M. Ageing Res Rev 2024

Delirium
Meta-analysis
Prevention
Treatment
Umbrella review

Study on the causal relationship between educational attainment and delirium: A two-sample Mendelian randomization study Wan, X. Yu, H. Yang, M. Hou, W. Xie, J. Xu, K. Ma, Y. Ma, R. Wang, F. Xu, P. Heliyon 2024

Delirium
Educational attainment
Genetic level
Genome-wide association study (GWAS)
Mendelian randomization

Potential value of serum prealbumin and serum albumin in the identification of postoperative delirium in patients undergoing knee/hip replacement: an observational study and internal validation study Wang, B. Xin, Y. Tang, X. Wang, F. Hua, S. Yang, Y. Xu, S. Gong, H. Dong, R. Lin, Y. Li, C. Lin, X. Bi, Y. Front Neurol 2024

biomarkers
neurodegeneration
perioperative neurocognitive disorders
serum albumin
serum prealbumin

Understanding the association between pain and delirium in older hospital inpatients: systematic review and meta-analysis White, N. Bazo-Alvarez, J. C. Koopmans, M. West, E. Sampson, E. L. Age Ageing 2024

Humans
Aged
*Inpatients
Pain/diagnosis/epidemiology
Pain Management
Hospitals
*Delirium/diagnosis/epidemiology
analgesia
delirium
general hospitals
older people
pain
systematic review

Prognostic value of Geriatric-8 for adverse outcomes within 30 days of surgery in older adults with colorectal cancer: A retrospective cohort study Winters, A. M. Bakker, J. Ten Hoor, J. Bilo, H. J. G. Roodbol, P. F. Edens, M. A. Finnema, E. J. Eur J Oncol Nurs 2024

Cognitive decline
Complication
Delirium
Geriatric assessment
Mortality

An online delirium detection tool: Cross-cultural adaptation of a Chinese version of the Family Confusion Assessment Method Xing, H. Zhu, S. Liu, S. Xia, M. Tong, S. Li, L. Li, L. Aust Crit Care 2024

Delirium
Family Confusion Assessment Method (FAM-CAM)
Intensive care unit (ICU)
Nursing

Value of Flemish Version of the Triage Risk Screening Tool in Predicting Unfavorable Outcomes after Elective Cancer Surgery: A Propensity Score-Matched Retrospective Cohort Study Yajima, S. Nakanishi, Y. Ogasawara, R. A. Imasato, N. Hirose, K. Katsumura, S. Kataoka, M. Masuda, H. Biomed Hub 2024

Delirium
Geriatric screening tool
Screening
Urology
fTRST

Impact of intraoperative dexmedetomidine on postoperative delirium and pro-inflammatory cytokine levels in elderly patients undergoing thoracolumbar compression fracture surgery: A prospective, randomized, placebo-controlled clinical trial Ye, C. Shen, J. Zhang, C. Hu, C. Medicine (Baltimore) 2024

Humans
*Dexmedetomidine/therapeutic use/administration & dosage
Female
Male
Double-Blind Method
Aged
*Cytokines/cerebrospinal fluid/metabolism
*Fractures, Compression/surgery
*Thoracic Vertebrae
Prospective Studies
*Postoperative Complications/prevention & control/drug therapy/cerebrospinal
fluid
Lumbar Vertebrae/surgery
Spinal Fractures/surgery
Delirium/prevention & control/cerebrospinal fluid/etiology/drug therapy
Intraoperative Care/methods
Middle Aged

Development and validation of a machine learning model to predict postoperative delirium using a nationwide database: A retrospective, observational study Yoshimura, M. Shiramoto, H. Koga, M. Morimoto, Y. J Clin Anesth 2024

Machine learning model
Postoperative delirium
Predictive model

Tau and delirium superimposed on dementia: A case report Yu, P. C. Kuo, C. M. Chen, I. C. SAGE Open Med Case Rep 2024

Tau
delirium superimposed on dementia
postoperative delirium
subacute delirium

Quetiapine Versus Haloperidol in the Management of Hyperactive Delirium: Randomized Controlled Trial Zakhary, T. Ahmed, I. Luttfi, I. Montasser, M. Neurocrit Care 2024

Antipsychotics
Delirium
Haloperidol
Hyperactive
Quetiapine

Associations between postoperative cognitive dysfunction, serum interleukin-6 and postoperative delirium among patients after coronary artery bypass grafting: A mediation analysis Zhang, S. Tao, X. J. Ding, S. Feng, X. W. Wu, F. Q. Wu, Y. Nurs Crit Care 2024

cardiac surgery
delirium assessment and management
early recognition
survey design

Risk prediction models for postoperative delirium in elderly patients with fragility hip fracture: A systematic review and critical appraisal Zhou, B. Wang, A. Cao, H. Int J Orthop Trauma Nurs 2024

Humans
Aged
*Emergence Delirium
Systematic Reviews as Topic
*Hip Fractures/surgery
Prognosis
Risk Assessment
Elderly
Fragility hip fracture
Postoperative delirium
Prediction models
Systematic review

An exploratory study on the heterogeneity of postoperative delirium: Preoperative cognitive screening does not detect hallucinatory delirium risk Yajima, S. Nakanishi, Y. Ogasawara, R. A. Imasato, N. Hirose, K. Katsumura, S. Kataoka, M. Masuda, H. Eur J Surg Oncol 2024

Humans
Aged
*Emergence Delirium
*Delirium/diagnosis/epidemiology/psychology
Retrospective Studies
Risk Factors
Prospective Studies
Hallucinations/diagnosis
Cognition
Postoperative Complications/prevention & control
Geriatric Assessment
Delirium
Hallucinations
Urology

Validation of a viable delirium detection test performed by nurses and physicians during routine patient care Soboh, R. Gino-Moor, S. Jiris, N. Ginsberg, S. Oliven, R. BMC Geriatr 2024

Humans
Aged
*Delirium/diagnosis/psychology
*Emergence Delirium
Critical Care
Inpatients
*Cognitive Dysfunction
4at
Delirium
Diagnosis
Non-inferiority
Validity

Does Comprehensive Geriatric Assessment Reduce the Incidence of Postoperative Delirium? A Quasi-experimental Study in Older Adults Undergoing Transcatheter Aortic Valve Implantation Schwesinger, A. Tsai, L. T. Lang, W. Mantegazza, N. Bauernschmitt, R. Wilhelm, M. J. Bischoff-Ferrari, H. A. Gagesch, M. Clin Interv Aging 2024

Humans
Female
Aged
Aged, 80 and over
Male
*Emergence Delirium
Geriatric Assessment
Incidence
Retrospective Studies
*Transcatheter Aortic Valve Replacement/adverse effects
Pops
Tavi
aortic stenosis
delirium
frail older adults
perioperative care

Butyrylcholinesterase activity in patients with postoperative delirium after cardiothoracic surgery or percutaneous valve replacement- an observational interdisciplinary cohort study Schlake, K. Teller, J. Hinken, L. Laser, H. Lichtinghagen, R. Schäfer, A. Fegbeutel, C. Weissenborn, K. Jung, C. Worthmann, H. Gabriel, M. M. BMC Neurol 2024

Aged
Humans
Butyrylcholinesterase
Cohort Studies
*Delirium/epidemiology/etiology
*Diabetes Mellitus, Type 2/complications
*Emergence Delirium/complications
Postoperative Complications/epidemiology/etiology
Prospective Studies
Risk Factors
Cardiac surgery
Percutaneous valve replacement
Postoperative delirium

Diagnostic accuracy of the pediatric CAM-ICU, pre-school CAM-ICU, Pediatric Anesthesia Emergence Delirium and Cornell Assessment of Pediatric Delirium for detecting delirium in the pediatric intensive care unit: A systematic review and meta-analysis Rohmah, I. Chen, Y. C. Lin, C. J. Tsao, N. H. Chiu, H. Y. Intensive Crit Care Nurs 2024

Humans
Child, Preschool
Child
*Delirium/epidemiology
*Emergence Delirium/diagnosis/complications
Intensive Care Units
Pediatric Anesthesia
Reproducibility of Results
Intensive Care Units, Pediatric
Critical care
Delirium
Pediatric intensive care delirium screening checklist
Pediatric intensive care unit

Intraoperative Use of Phenylephrine versus Ephedrine and Postoperative Delirium: A Multicenter Retrospective Cohort Study Ma, H. Ahrens, E. Wachtendorf, L. J. Suleiman, A. Shay, D. Munoz-Acuna, R. Tartler, T. M. Teja, B. Wagner, S. Subramaniam, B. Rhee, J. Schaefer, M. S. Anesthesiology 2024

Adult
Humans
Phenylephrine/adverse effects
Ephedrine/adverse effects
Vasoconstrictor Agents/therapeutic use
*Emergence Delirium/complications
Retrospective Studies
*Hypotension/chemically induced/epidemiology

Effect of clock rhythm on emergence agitation and early postoperative delirium in older adults undergoing thoracoscopic lung cancer surgery: protocol for a prospective, observational, cohort study Jiang, L. Wang, J. Chen, W. Wang, Z. Xiong, W. BMC Geriatr 2024

Humans
Aged
*Emergence Delirium/epidemiology
*Melatonin
Prospective Studies
Cohort Studies
*Lung Neoplasms
Postoperative Complications/epidemiology
Observational Studies as Topic
Clock rhythm
Early postoperative delirium
Emergence agitation
Older adults

Scientific rationale for the use of α2A-adrenoceptor agonists in treating neuroinflammatory cognitive disorders Arnsten, A. F. T. Ishizawa, Y. Xie, Z. Mol Psychiatry 2023

Humans
Calcium Signaling
*Cognitive Dysfunction
*Delirium
Guanfacine/pharmacology/therapeutic use
Neuroinflammatory Diseases
Post-Acute COVID-19 Syndrome
Prefrontal Cortex

The role of perioperative sedative anesthetics in preventing postoperative delirium: a systematic review and network-meta analysis including 6679 patients Huang, J. X. Zhang, S. S. Wang, S. X. Xi, D. S. Luo, F. R. Liu, C. J. Li, H. BMC Cardiovasc Disord 2024

PMID: 38448835

PMCID: PMC10916082

Preventive Effects of Melatonin on Delirium in Intensive Care Unit Patients: A Meta-Analysis of Randomized Controlled Trials Zhao, L. Feng, Z. Wang, Q. Jiang, Z. Qiu, X. Altern Ther Health Med 2024

ICU

Delirium

Melatonin

Length of Stay

Meta-Analysis

Mechanical Ventilation

Mitochondrial Dysfunction of Peripheral Platelets as a Predictive Biomarker for Postoperative Delirium in Elderly Patients Yang, Y. Zhang, W. Liu, Y. Liu, X. Xie, J. Xu, R. Huang, Y. Hao, J. Sun, Y. Gu, X. Ma, Z. Ann Neurol 2024

Postoperative Delirium

Bioenergetic Health Index

Surgery

Mitochondria

MMSE

 

Effect of Esketamine on Postoperative Delirium in Patients Undergoing Cardiac Valve Replacement with Cardiopulmonary Bypass: A Randomized Controlled Trial Xiong, X. Shao, Y. Chen, D. Chen, B. Lan, X. Shi, J. Anesth Analg 2024

Postoperative Delirium

Esketamine

Cardiac Valve Replacement

Cardiopulmonary Bypass

CAM

CAM-ICU

MMSE

Prolonged Hourly Neurologic Examinations are Associated with Increased Delirium and No Discernible Benefit in Mild/Moderate Geriatric Traumatic Brain Injury Ruiz, R. A. F. Canas, M. Diaz, L. Aldana, J. A. Afzal, H. Falcon, A. F. Del Toro, D. Day, A. McCarthy, J. Stansfield, K. Bochicchio, G. V. Niziolek, G. Kranker, L. M. Rosengart, M. R. Hoofnagle, M. Leonard, J. J Trauma Acute Care Surg 2024

NeuroChecks

Delirium

TBI

CAM-ICU

Association of Intravenous Neostigmine and Anticholinergics or Sugammadex with Postoperative Delirium: A Retrospective Cohort Study Rössler, J. Abramczyk, E. Paredes, S. Anusic, N. Pu, X. Maheshwari, K. Turan, A. Ruetzler, K. Anesth Analg 2024

bCAM

Postoperative Delirium

Sugammadex

Neostigmine

Anesthesia

Noncardiac Surgery

Metformin Use in Type 2 Diabetics and Delirium After Noncardiac Surgery: A Retrospective Cohort Analysis Paredes, S. Harb, A. Rössler, J. Nikoo, M. Z. Ruetzler, K. Turan, A. Pu, X. Sessler, D. I. Anesth Analg 2024

Type 2 Diabetes

CAM-ICU

bCAM

Postoperative Delirium

Metformin

 

Preoperative Intrathecal Morphine is Associated With Reduced Postoperative Pain, Agitation, and Delirium In Living Donor Kidney Transplantation Recipients Lee, J. E. Lee, K. W. Gil, E. Park, J. B. Kim, B. J. Kim, H. Y. Kim, G. S. Transplant Proc 2024

Kidney Transplant

Postoperative Delirium

Intrathecal Morphine

CAM-ICU

Postoperative Pain

Anesthesia

Neuropsychological follow-up of isoflurane sedated intensive care patients: a substudy of a randomized trial Fuchs, V. F. Simon, H. V. Soldinger, N. Volk, T. Meiser, A. Minerva Anestesiol 2024

Critical care

Isoflurane

Propofol

Delirium

Feasibility and Acceptability of Using Wireless Limited Polysomnography to Capture Sleep Before, During, and After Hospitalization for Patients With Planned Cardiothoracic Surgery Cordoza, M. L. Anderson, B. J. Cevasco, M. Diamond, J. M. Younes, M. Gerardy, B. Iroegbu, C. Riegel, B. J Cardiovasc Nurs 2024

Critical Illness

Intensive Care Unit

Polysomnography

Sleep

Thoracic Surgery

Antipsychotics in the Treatment of Delirium in Critically Ill Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Carayannopoulos, K. L. Alshamsi, F. Chaudhuri, D. Spatafora, L. Piticaru, J. Campbell, K. Alhazzani, W. Lewis, K. Crit Care Med 2024

Antipsychotic medication

Delirium

Systematic review

Critically Ill

Cognitive Impairment

Coma

Burnout and perceived burden levels related to delirium in physicians and nurses Yamagata, H. Takihara, T. Kobayashi, R. Hirose, K. Higuchi, K. Miyahara, M. Komatsu, D. Gen Hosp Psychiatry 2024

Humans
*Burnout, Professional/epidemiology
Burnout, Psychological
*Physicians
*Delirium/epidemiology
Surveys and Questionnaires
*Nurses

Bell's mania as a clinical presentation in a neurosurgical setting from a tertiary care neuropsychiatric hospital in India Mamtani, H. Utagi, S. Chaurasia, K. K. Reddy, P. V. Arasappa, R. Prasad, C. Srinivas, D. Rao, M. B. Thippeswamy, H. Indian J Psychiatry 2024

Craniopharyngioma
delirious mania
delirium
dural arteriovenous fistula
mania

Correlation analysis between plasma biomarkers albumin, fibrinogen, and their ratio with postoperative delirium in patients undergoing non-cardiac surgery: a systematic review and meta-analysis Lu, Z. Wang, B. Liu, M. Yu, D. Li, J. Am J Transl Res 2024

Albumin
albumin-fibrinogen ratio (AFR)
fibrinogen
meta-analysis
plasma biomarkers
postoperative delirium

Risk factors for hypoactive delirium in patients with nontraumatic ARDS: a prospective observational study Lian, F. Li, F. Tang, X. Yuan, Y. Sci Rep 2024

Humans
Interleukin-6
*Respiratory Distress Syndrome/complications/therapy
Intensive Care Units
Risk Factors
Hypokinesia
*Diabetes Mellitus
*Delirium/epidemiology/etiology/diagnosis
Retrospective Studies
Hypoactive delirium
Il-6
Intensive care unit
Nontraumatic ARDS
Risk factor