What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Exercise for acutely hospitalised older medical patients
- Authors
- Hartley, P. Keating, J. L. Jeffs, K. J. Raymond, M. J. Smith, T. O
- Year
- 2022
- Journal
- Cochrane Database Syst Rev
- Abstract
BACKGROUND: Approximately 30% of hospitalised older adults experience hospital-associated functional decline. Exercise interventions that promote in-hospital activity may prevent deconditioning and thereby maintain physical function during hospitalisation. This is an update of a Cochrane Review first published in 2007. OBJECTIVES: To evaluate the benefits and harms of exercise interventions for acutely hospitalised older medical inpatients on functional ability, quality of life (QoL), participant global assessment of success and adverse events compared to usual care or a sham-control intervention. SEARCH METHODS: We used standard, extensive Cochrane search methods. The latest search date was May 2021. SELECTION CRITERIA: We included randomised or quasi-randomised controlled trials evaluating an in-hospital exercise intervention in people aged 65 years or older admitted to hospital with a general medical condition. We excluded people admitted for elective reasons or surgery. DATA COLLECTION AND ANALYSIS: We used standard Cochrane methods. Our major outcomes were 1. independence with activities of daily living; 2. functional mobility; 3. new incidence of delirium during hospitalisation; 4. QoL; 5. number of falls during hospitalisation; 6. medical deterioration during hospitalisation and 7. participant global assessment of success. Our minor outcomes were 8. death during hospitalisation; 9. musculoskeletal injuries during hospitalisation; 10. hospital length of stay; 11. new institutionalisation at hospital discharge; 12. hospital readmission and 13. walking performance. We used GRADE to assess certainty of evidence for each major outcome. We categorised exercise interventions as: rehabilitation-related activities (interventions designed to increase physical activity or functional recovery, but did not follow a specified exercise protocol); structured exercise (interventions that included an exercise intervention protocol but did not include progressive resistance training); and progressive resistance exercise (interventions that included an element of progressive resistance training). MAIN RESULTS: We included 24 studies (nine rehabilitation-related activity interventions, six structured exercise interventions and nine progressive resistance exercise interventions) with 7511 participants. All studies compared exercise interventions to usual care; two studies, in addition to usual care, used sham interventions. Mean ages ranged from 73 to 88 years, and 58% of participants were women. Several studies were at high risk of bias. The most common domain assessed at high risk of bias was measurement of the outcome, and five studies (21%) were at high risk of bias arising from the randomisation process. Exercise may have no clinically important effect on independence in activities of daily living at discharge from hospital compared to controls (16 studies, 5174 participants; low-certainty evidence). Five studies used the Barthel Index (scale: 0 to 100, higher scores representing greater independence). Mean scores at discharge in the control groups ranged from 42 to 96 points, and independence in activities of daily living was 1.8 points better (0.43 worse to 4.12 better) with exercise compared to controls. The minimally clinical important difference (MCID) is estimated to be 11 points. We are uncertain regarding the effect of exercise on functional mobility at discharge from the hospital compared to controls (8 studies, 2369 participants; very low-certainty evidence). Three studies used the Short Physical Performance Battery (SPPB) (scale: 0 to 12, higher scores representing better function) to measure functional mobility. Mean scores at discharge in the control groups ranged from 3.7 to 4.9 points on the SPPB, and the estimated effect of the exercise interventions was 0.78 points better (0.02 worse to 1.57 better). A change of 1 point on the SPPB represents an MCID. We are uncertain regarding the effect of exercise on the incidence of delirium during hospitalisation compared to controls (7 trials, 2088 participants; very low-certainty evidence). The incidence of delirium during hospitalisation was 88/1091 (81 per 1000) in the control group compared with 70/997 (73 per 1000; range 47 to 114) in the exercise group (RR 0.90, 95% CI 0.58 to 1.41). Exercise interventions may result in a small clinically unimportant improvement in QoL at discharge from the hospital compared to controls (4 studies, 875 participants; low-certainty evidence). Mean QoL on the EuroQol 5 Dimensions (EQ-5D) visual analogue scale (VAS) (scale: 0 to 100, higher scores representing better QoL) ranged between 48.9 and 64.7 in the control group at discharge from the hospital, and QoL was 6.04 points better (0.9 better to 11.18 better) with exercise. A change of 10 points on the EQ-5D VAS represents an MCID. No studies measured participant global assessment of success. Exercise interventions did not affect the risk of falls during hospitalisation (moderate-certainty evidence). The incidence of falls was 31/899 (34 per 1000) in the control group compared with 31/888 (34 per 1000; range 20 to 57) in the exercise group (RR 0.99, 95% CI 0.59 to 1.65). We are uncertain regarding the effect of exercise on the incidence of medical deterioration during hospitalisation (very low-certainty evidence). The incidence of medical deterioration in the control group was 101/1417 (71 per 1000) compared with 96/1313 (73 per 1000; range 44 to 120) in the exercise group (RR 1.02, 95% CI 0.62 to 1.68). Subgroup analyses by different intervention categories and by the use of a sham intervention were not meaningfully different from the main analyses. AUTHORS’ CONCLUSIONS: Exercise may make little difference to independence in activities of daily living or QoL, but probably does not result in more falls in older medical inpatients. We are uncertain about the effect of exercise on functional mobility, incidence of delirium and medical deterioration. Certainty of evidence was limited by risk of bias and inconsistency. Future primary research on the effect of exercise on acute hospitalisation could focus on more consistent and uniform reporting of participant’s characteristics including their baseline level of functional ability, as well as exercise dose, intensity and adherence that may provide an insight into the reasons for the observed inconsistencies in findings.
- PMID
- Keywords
Aged
Aged, 80 and over
Female
Humans
Male
Activities of Daily Living
*Delirium/epidemiology
Exercise
*Quality of Life
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Adverse events related to physical restraint use in intensive care units: A review of the literature | Berger, S. Grzonka, P. Amacher, S. A. Hunziker, S. Frei, A. I. Sutter, R. | J Intensive Med | 2024 |
Adverse event |
| Managing Postoperative Delirium in Patients Receiving Head and Neck Surgery: An Educational Overview | Babu, S. Kurian Sajith, B. | Clin J Oncol Nurs | 2024 |
Humans |
| Risk Factors for Postoperative Delirium Severity After Deep Brain Stimulation Surgery in Parkinson's Disease | Astalosch, M. Mousavi, M. Ribeiro, L. M. Schneider, G. H. Stuke, H. Haufe, S. Borchers, F. Spies, C. von Hofen-Hohloch, J. Al-Fatly, B. Ebersbach, G. Franke, C. Kühn, A. A. Kübler-Weller, D. | J Parkinsons Dis | 2024 |
Parkinson’s disease |
| A Dual-Camera Eye-Tracking Platform for Rapid Real-Time Diagnosis of Acute Delirium: A Pilot Study | Al-Hindawi, A. Vizcaychipi, M. Demiris, Y. | IEEE J Transl Eng Health Med | 2024 |
Humans |
| Effectiveness of nurse-led non-pharmacological interventions on outcomes of delirium in adults: A meta-analysis of randomized controlled trials | Wang, J. Lu, Y. Chen, X. Wu, Y. | Worldviews Evid Based Nurs | 2024 |
adult health |
| Association of blood glucose change with postoperative delirium after coronary artery bypass grafting in patients with diabetes mellitus: a study of the MIMIC-IV database | Wang, F. Mei, X. | Front Endocrinol (Lausanne) | 2024 |
Humans |
| The genetic relationship between hypotension and delirium: a Mendelian randomization study | Wang, C. Wu, J. Lin, Y. Liu, Z. Liufu, N. Cao, M. | Front Neurol | 2024 |
Mendelian randomization |
| Comparison of Propofol-Based Total Intravenous Anesthesia versus Volatile Anesthesia with Sevoflurane for Postoperative Delirium in Adult Coronary Artery Bypass Grafting Surgery: A Prospective Randomized Single-Blinded Study | Varsha, A. V. Unnikrishnan, K. P. Saravana Babu, M. S. Raman, S. P. Koshy, T. | J Cardiothorac Vasc Anesth | 2024 |
cardiopulmonary bypass |
| Diagnostics and treatment of impulse control disorders, psychosis and delirium: systemic review-based recommendations - guideline "Parkinson's disease" of the German Society of Neurology | Witt, K. Levin, J. van Eimeren, T. Hasan, A. Ebersbach, G. | J Neurol | 2024 |
Delirium |
| Potential mechanism of Taohong Siwu Decoction in preventing and treating postoperative delirium in intertrochanteric fracture patients based on retrospective analysis and network pharmacology | Ding, Z. Yu, Z. Sun, Z. Liu, X. Chen, R. | J Orthop Surg Res | 2024 |
Humans |
| Electroencephalography-Guided Anesthesia and Delirium in Older Adults After Cardiac Surgery: The ENGAGES-Canada Randomized Clinical Trial | Deschamps, A. Ben Abdallah, A. Jacobsohn, E. Saha, T. Djaiani, G. El-Gabalawy, R. Overbeek, C. Palermo, J. Courbe, A. Cloutier, I. Tanzola, R. Kronzer, A. Fritz, B. A. Schmitt, E. M. Inouye, S. K. Avidan, M. S. | Jama | 2024 |
Postoperative Delirium Anesthesia EEG-guided anesthesia Intraoperative EEG waveform suppression Older Adults |
| Association Between Pupil Light Reflex and Delirium in Adults With Traumatic Brain Injury: Preliminary Findings | Lapierre, A. Proulx, A. Gélinas, C. Dollé, S. Alexander, S. Williamson, D. Bernard, F. Arbour, C. | J Neurosci Nurs | 2024 |
Delirium ICU Delirium Traumatic Brain Injury Pupillary light reflex Postextubation delirium
|
| Prevalence and risk factors of postoperative delirium in tumor patients after free flap reconstruction: A systematic review and meta-analysis of case-control studies | Li, Y. Li, Z. Lv, Q. Gu, Y. Qi, Y. Li, J. Liu, Y. Ma, G. | Surgery | 2024 |
Postoperative Delirium Flap transplantation surgery Risk Factors Proactive prevention measures Systematic Review |
| Risk factors and risk stratification approaches for delirium screening: A Geriatric Emergency Department Guidelines 2.0 systematic review | Seidenfeld, J. Lee, S. Ragsdale, L. Nickel, C. H. Liu, S. W. Kennedy, M. | Acad Emerg Med | 2024 |
Geriatrics Delirium Emergency Department delirium screening Risk factors Delirium risk scores Systematic review |
| Examining the impact of permissibility hypercapnia on postoperative delirium among elderly patients undergoing thoracoscopic-laparoscopic esophagectomy: A single-center investigative study | Song, J. Shao, Y. M. Zhang, G. H. Fan, B. Q. Tao, W. H. Liu, X. F. Huang, X. C. Hu, X. W. | Shock | 2024 |
Postoperative delirium Permissive hypercapnia ventilation thoracic surgery intraoperative respiration |
| Association between modified frailty index and postoperative delirium in patients after cardiac surgery: A cohort study of 2080 older adults | Cheng, H. Ling, Y. Li, Q. Li, X. Tang, Y. Guo, J. Li, J. Wang, Z. Ming, W. K. Lyu, J. | CNS Neurosci Ther | 2024 |
Humans |
| Role of Intraoperative Electroencephalography in Predicting Postoperative Delirium in Patients Undergoing Cardiovascular Surgeries | Al-Qudah, A. M. Sivaguru, S. Anetakis, K. Crammond, D. J. Balzer, J. R. Thirumala, P. D. Subramaniam, K. Sadhasivam, S. Shandal, V. | Clin Neurophysiol | 2024 |
Cardiopulmonary bypass |
| Differences in metalloproteinases and their tissue inhibitors in the cerebrospinal fluid are associated with delirium | Aksnes, M. Schibstad, M. H. Chaudhry, F. A. Neerland, B. E. Caplan, G. Saltvedt, I. Eldholm, R. S. Myrstad, M. Edwin, T. H. Persson, K. Idland, A. V. Pollmann, C. T. Olsen, R. B. Wyller, T. B. Zetterberg, H. Cunningham, E. Watne, L. O. | Commun Med (Lond) | 2024 |
Alzheimer’s disease, Diagnostic markers, Dementia |
| A retrospective cohort study comparing outcomes following hip fractures in Australian indigenous patients with non-Australian indigenous patients | Cheok, T. Bastick, K. George, D. Chan, T. S. Jaitly, A. Jayasekera, N. Bray, L. Poonnoose, P. M. Williams, K. | ANZ J Surg | 2024 |
hip fracture |
| Comparing BIS Monitoring vs. Clinical Assessment for Deep Sedation in the ICU: Effects on Delirium Reduction and Sedative Drug Doses - A randomized trial | Huespe, I. Giunta, D. Acosta, K. Avila, D. Prado, E. Sanghavi, D. Carboni Bisso, I. Giannasi, S. Carini, F. C. | Chest | 2024 |
Bispectral Index,electroencephalogram-based sedation |
| Pharmacologic Management of End-of-Life Delirium: Translating Evidence into Practice | Hui, D. Cheng, S. Y. Paiva, C. E. | Cancers (Basel) | 2024 |
antipsychotic agents |
| Boarding Duration in the Emergency Department and Inpatient Delirium and Severe Agitation | Joseph, J. W. Elhadad, N. Mattison, M. L. P. Nentwich, L. M. Levine, S. A. Marcantonio, E. R. Kennedy, M. | JAMA Netw Open | 2024 |
Humans |
| Boarding Duration in the Emergency Department and Inpatient Delirium and Severe Agitation | Joseph, J. W. Elhadad, N. Mattison, M. L. P. Nentwich, L. M. Levine, S. A. Marcantonio, E. R. Kennedy, M. | JAMA Netw Open | 2024 |
Humans |
| Perioperative Blood Transfusion and Delirium after Total Knee or Hip Arthroplasty: Retrospective Analysis | Kim, S. Oh, T. K. Song, I. A. | J Pers Med | 2024 |
blood trans fusion |
| Randomized feasibility trial for evaluating the impact of primary nursing on delirium duration during intensive care unit stay | Krüger, L. Zittermann, A. Mannebach, T. Wefer, F. Becker, T. Lohmeier, S. Lüttermann, A. von Dossow, V. Rojas, S. V. Gummert, J. Langer, G. | Intensive Crit Care Nurs | 2024 |
Delirium |
| Patient recall of intensive care delirium: A qualitative investigation | la Cour, K. N. Andersen-Ranberg, N. C. Mortensen, C. Poulsen, L. M. Mathiesen, O. Egerod, I. Collet, M. | Acta Anaesthesiol Scand | 2024 |
critical care |
| Sevoflurane multiple Wash In/Wash Out at the end of anesthesia to reduce agitation: A multicenter double-blind randomized controlled trial | Landoni, G. Likhvantsev, V. V. Berikashvili, L. B. Yavorovsky, A. G. Bagdasarov, P. S. Smirnova, A. V. Serkova, T. S. Subbotin, V. V. Kadantseva, K. K. Ovezov, A. M. Yadgarov, M. Y. Yakovlev, A. A. Lamacchia, A. Gallo, L. Gracheva, N. D. Ryzhkov, P. V. Zi | Contemp Clin Trials Commun | 2024 |
Anesthesia |
| Predictive model and discriminant analysis of the development of dementia in patients with delirium in the emergency department | Lupiáñez Seoane, P. Muñoz Negro, J. E. Torres Parejo, U. Gómez Jiménez, F. J. | Semergen | 2024 |
Comorbidity |
| Machine learning for the prediction of delirium in elderly intensive care unit patients | Ma, R. Zhao, J. Wen, Z. Qin, Y. Yu, Z. Yuan, J. Zhang, Y. Wang, A. Li, C. Li, H. Chen, Y. Han, F. Zhao, Y. Sun, S. Ning, X. | Eur Geriatr Med | 2024 |
Delirium |
| A Novel Preoperative Electroencephalogram-Derived Index to Predict Early Postoperative Delirium in Elderly Patients After Hip Fracture Surgeries: Development of a Prediction Model | Nawan, A. Wang, G. Zhao, C. Zhang, W. Jiang, B. Feng, Y. | Geriatr Orthop Surg Rehabil | 2024 |
delirium index |
| Fixed dose ketamine for prehospital management of hyperactive delirium with severe agitation | O'Brien, M. C. Kelleran, K. J. Burnett, S. J. Hausrath, K. A. Kneer, M. S. Nan, N. Ma, C. X. McCartin, R. W. Clemency, B. M. | Am J Emerg Med | 2024 |
Humans |
| Platelet Bioenergetics and Associations With Delirium and Coma in Patients With Sepsis: A Prospective Cohort Study | Onyemekwu, C. A. Prendergast, N. T. Potter, K. M. Toney, N. A. Nouraie, M. S. Shiva, S. Girard, T. D. | CHEST Crit Care | 2024 |
acute brain dysfunction |
| Enhancing European Management of Analgesia, Sedation, and Delirium: A Multinational, Prospective, Interventional Before-After Trial | Paul, N. Grunow, J. J. Rosenthal, M. Spies, C. D. Page, V. J. Hanison, J. Patel, B. Rosenberg, A. von Haken, R. Pietsch, U. Schrag, C. Waydhas, C. Schellongowski, P. Lobmeyr, E. Sander, M. Piper, S. K. Conway, D. Totzeck, A. Weiss, B. | Neurocrit Care | 2024 |
Humans |
| EEG and acute confusional state at the emergency department | Prud'hon, S. Amiel, H. Zanin, A. Revue, E. Kubis, N. Lozeron, P. | Neurophysiol Clin | 2024 |
Humans |
| Preoperative Delirium Risk Screening in Patients Undergoing a Cardiac Surgery: Results from the Prospective Observational FINDERI Study | Sadlonova, M. Hansen, N. Esselmann, H. Celano, C. M. Derad, C. Asendorf, T. Chebbok, M. Heinemann, S. Wiesent, A. Schmitz, J. Bauer, F. E. Ehrentraut, J. Kutschka, I. Wiltfang, J. Baraki, H. von Arnim, C. A. F. | Am J Geriatr Psychiatry | 2024 |
Humans |
| Predicting postoperative delirium after percutaneous transluminal angioplasty and stenting in patients with intracranial atherosclerotic stenosis | Zhu, W. Shen, Y. Zhao, H. Tang, Y. Wang, X. Li, S. | Neurol Res | 2024 |
Postoperative delirium |
| Factors contributing to sepsis-associated encephalopathy: a comprehensive systematic review and meta-analysis | Zhang, Z. Guo, L. Jia, L. Duo, H. Shen, L. Zhao, H. | Front Med (Lausanne) | 2024 |
delirium |
| Impact of delirium intervention on cognitive load among nurses in the intensive care unit: A multi-centre cluster randomized controlled trial | Zhang, S. Ji, M. Cui, W. Wei, J. Ding, S. Wu, Y. | Int J Nurs Pract | 2024 |
Humans |
| Incidence and risk factors of post-operative delirium in glioma patients: A prospective cohort study in general wards | Yuan, C. Cheng, Z. Liu, Y. You, Y. Wang, L. Li, D. Zhong, L. | J Clin Nurs | 2024 |
general ward |
| Effect of Morphine Used to Relieve Dyspnea Due to Heart Failure on Delirium | Yoshikai, S. Ueda, M. Ikeda, K. | J Palliat Med | 2024 |
delirium |
| Association of Delirium with Long-Term Mortality in Critically Ill Patients with COPD Who Survived to Discharge: A Retrospective Cohort Study | Xu, H. B. Xue, F. Ye, Y. Zhang, H. G. | Lung | 2024 |
Copd |
| Effect of obstructive sleep apnea on postoperative delirium: a system review and meta-analysis | Xiao, Y. Li, P. J. Guo, M. Y. Cao, Y. Liang, Z. A. | Sleep Breath | 2024 |
Delirium |
| A qualitative study of geriatric specialist nurses' experiences to navigate delirium in the elderly | Wu, M. Chen, Z. Xu, Y. Zhao, L. Zhao, L. Xia, L. | BMC Nurs | 2024 |
Care |
| The influence of low-dose s-ketamine on postoperative delirium and cognitive function in older adults undergoing thoracic surgery | Wang, Y. Ma, B. Wang, C. Wang, Y. Liu, A. Hang, L. | J Cardiothorac Surg | 2024 |
Humans |
| Neurological diagnostic tests for patients with and without delirium: a prospective observational study | Waefler, N. Abid, I. Montaut, V. Donzé, J. Zender, H. John, G. | Geroscience | 2024 |
CT scan |
| Preoperative cognitive function as a risk factor of postoperative delirium in cancer surgeries: A systematic review and meta-analysis | Varpaei, H. A. Robbins, L. B. Farhadi, K. Bender, C. M. | J Surg Oncol | 2024 |
cancer survivors |
| Role of oral melatonin in prevention of postoperative delirium in patients undergoing elective surgery under general anesthesia: A Randomized controlled trial | Thakur, T. Saini, V. Grover, S. Samra, T. | Indian J Psychiatry | 2024 |
Anxiety |
| Clinical characteristics of delirium in older patients with first-ever acute myocardial infarction who underwent percutaneous coronary intervention : A retrospective study | Tan, J. F. Duan, L. Han, J. C. Cui, J. J. | Herz | 2024 |
Acute myocardial infarction |
| Antibiotics for delirium in older adults with pyuria or bacteriuria: A systematic review | Stall, N. M. Kandel, C. Reppas-Rindlisbacher, C. Quinn, K. L. Wiesenfeld, L. MacFadden, D. R. Johnstone, J. Fralick, M. | J Am Geriatr Soc | 2024 |
antibiotics |
| Establishment and validation of the prediction model for postoperative delirium risk factors in older patients after total knee arthroplasty: A retrospective study | Song, L. X. Qin, Y. Yang, L. Xing, D. B. Li, Y. Lei, F. Q. Wang, L. H. | Medicine (Baltimore) | 2024 |
Humans |
| Predictive value of the Naples prognostic score on postoperative delirium in the elderly with gastrointestinal tumors: a retrospective cohort study | Song, C. Yu, D. Li, Y. Liu, M. Zhang, H. He, J. Li, J. | BMC Geriatr | 2024 |
Humans |
| Effect of prophylactic corticosteroids on postoperative neurocognitive dysfunction in the adult population: An updated systematic review, meta-analysis, and trial sequential analysis of randomised controlled trials | Singh, N. P. Makkar, J. K. Goel, N. Karamchandani, K. Singh, M. Singh, P. M. | Indian J Anaesth | 2024 |
Corticosteroids |
| Usefulness of the 4A's test for detecting delirium in critically ill patients: a multicenter prospective observation study | Sim, J. K. Chung, K. Chung, C. R. Lee, J. Hwang, S. Y. Lee, Y. S. | Intern Emerg Med | 2024 |
Critical illness |
| Incidence of Postoperative Delirium among Elderly Patients after Elective Surgeries under Anesthesia in the Charity Services of the Philippine General Hospital | Hermoso, R. M. L. Cruz, P. L. O. | Acta Med Philipp | 2024 |
elderly |
| Registered nurses' experiences of caring for patients with hypoactive delirium after cardiac surgery - A qualitative study | Hallberg Kristensen, A. Nymark, C. Stenman, M. Falk, A. | Intensive Crit Care Nurs | 2024 |
Cardiac surgical procedures |
| Determinants of delirium in elderly in-patients in a general ward setting in a teaching hospital: A case control study | Geetha, J. Babu, H. George, C. | Ind Psychiatry J | 2024 |
Delirium |
| Incidence and risk factors of delirium following brain tumor resection: A retrospective National Inpatient Sample database study | Fu, W. Li, Y. Liu, R. Li, J. | World Neurosurg | 2024 |
Brain tumor |
| Prolonged hourly neurological examinations are associated with increased delirium and no discernible benefit in mild/moderate geriatric traumatic brain injury | Fonseca, R. A. Canas, M. Diaz, L. Aldana, J. A. Afzal, H. De Filippis, A. Del Toro, D. Day, A. McCarthy, J. Stansfield, K. Bochicchio, G. V. Niziolek, G. Kranker, L. M. Rosengart, M. R. Hoofnagle, M. Leonard, J. | J Trauma Acute Care Surg | 2024 |
Humans |
| Nursing Intervention to Prevent and Manage Delirium in Critically Ill Patients: A Scoping Review | Fernandes, F. Santos, M. Anacleto, A. M. Jerónimo, C. Ferreira, Ó Baixinho, C. L. | Healthcare (Basel) | 2024 |
adult |
| Intraoperative electroencephalogram features related to frailty in older patients: an exploratory prospective observational study | Fang, P. P. Zhang, H. W. Hao, X. X. Shang, Z. X. Li, J. Liu, X. S. | J Clin Monit Comput | 2024 |
Humans |
| Managing Delirium in the Emergency Department: An Updated Narrative Review | Ehrlich, A. Oh, E. S. Ahmed, S. | Curr Geriatr Rep | 2024 |
Confusion |
| A narrative review of the development and performance characteristics of electronic delirium-screening tools | Eeles, E. Tran, D. D. Boyd, J. Tronstad, O. Teodorczuk, A. Flaws, D. Fraser, J. F. Dissanayaka, N. | Aust Crit Care | 2024 |
*Delirium/diagnosis |
| The Role of Neutrophil-to-Lymphocyte Ratio (NLR) in Urosepsis-Associated Delirium | Dragoescu, A. N. Padureanu, V. Stanculescu, A. D. Chiutu, L. Padureanu, R. Andrei, M. Radu, M. A. Mitroi, G. Dragoescu, P. O. | Cureus | 2024 |
diagnostic |
| Does Melatonin Decrease the Use of As-Needed Antipsychotics or Benzodiazepines in Noncritically Ill Hospitalized Patients? A Multicenter Retrospective Cohort Study | Dobry, P. Poparad-Stezar, A. Bacon, O. Boji, S. Giuliano, C. | J Integr Complement Med | 2024 |
Humans |
| Comparison of the frailty index and frailty phenotype and their associations with postoperative delirium incidence and severity | Deiner, S. G. Marcantonio, E. R. Trivedi, S. Inouye, S. K. Travison, T. G. Schmitt, E. M. Hshieh, T. Fong, T. G. Ngo, L. H. Vasunilashorn, S. M. | J Am Geriatr Soc | 2024 |
Humans |
| Frailty index and risk of delirium in hospitalized patients: a two-sample Mendelian randomization study | Chen, Y. Feng, F. Li, Q. Guo, H. Zhang, L. Liu, J. | Front Med (Lausanne) | 2024 |
Mendelian randomization study |
| Enhancing hospice care with psychological support and a nomogram to predict delirium in patients with advanced solid tumors | Chen, J. Huan, J. Chen, C. Xu, W. Jia, A. | Am J Cancer Res | 2024 |
Hospice care |
| The influence of sleep disorders on perioperative neurocognitive disorders among the elderly: A narrative review | Chen, C. Zhai, R. X. Lan, X. Yang, S. F. Tang, S. J. Xiong, X. L. He, Y. X. Lin, J. F. Feng, J. R. Chen, D. X. Shi, J. | Ibrain | 2024 |
insomnia |
| Prevalence of preoperative depression and adverse outcomes in older patients undergoing elective surgery: A systematic review and meta-analysis | Chen, A. An, E. Yan, E. Saripella, A. Khullar, A. Misati, G. Alhamdah, Y. Englesakis, M. Mah, L. Tartaglia, C. Chung, F. | J Clin Anesth | 2024 |
Delirium, older patients |
| Antipsychotic medications and severe sepsis in schizophrenia: A nested case-control study | Chang, C. W. Chen, W. Y. Chen, P. Y. Pan, C. H. Su, S. S. Tsai, S. Y. Chen, C. C. Kuo, C. J. | Aust N Z J Psychiatry | 2024 |
Sepsis |
| Selection of knowledge translation strategies to implement best practices on nonpharmacological prevention of delirium in intensive care unit | Boivin, A. Bérubé, M. | Rech Soins Infirm | 2024 |
Humans |
| Barriers to healthcare professionals recognizing and managing delirium in older adults during a hospital stay: A mixed-methods systematic review | Bianchi, L. A. Harris, R. Fitzpatrick, J. M. | J Adv Nurs | 2024 |
Humans |
| Burden of delirium on mortality and healthcare resource utilization in geriatric patients hospitalized for inflammatory bowel disease | Aldiabat, M. Aleyadeh, W. Rana, T. Ta'ani, O. A. Alahmad, M. Ayoub, M. Jaber, F. Obeidat, A. Numan, L. Manvar, A. Alhuneafat, L. | Proc (Bayl Univ Med Cent) | 2024 |
Geriatrics |
| Prophylactic Minocycline for Delirium in Critically Ill Patients: A Randomized Controlled Trial | Dal-Pizzol, F. Coelho, A. Simon, C. S. Michels, M. Corneo, E. Jeremias, A. Damásio, D. Ritter, C. | Chest | 2024 |
Humans |
| Clinical Significance of the Prognostic Nutritional Index in Predicting Delirium among Critically Ill Patients: A Retrospective Cohort Study | Xu, F. Zhong, X. | Crit Care Res Pract | 2024 |
Delirium Prognostic Nutrition Index ICU Critically ill patients MIMIC IV |
| Impact of Continuous Infusion Ketamine Compared to Continuous Infusion Benzodiazepines on Delirium in the Intensive Care Unit | Vollmer, N. J. Wieruszewski, E. D. Nei, A. M. Mara, K. C. Rabinstein, A. A. Brown, C. S. | J Intensive Care Med | 2024 |
benzodiazepines |
| Preoperative ketamine administration for prevention of postoperative neurocognitive disorders after major orthopedic surgery in elderly patients: A multicenter randomized blinded placebo-controlled trial | Verdonk, F. Lambert, P. Gakuba, C. Nelson, A. C. Lescot, T. Garnier, F. Constantin, J. M. Saurel, D. Lasocki, S. Rineau, E. Diemunsch, P. Dreyfuss, L. Tavernier, B. Bezu, L. Josserand, J. Mebazaa, A. Coroir, M. Nouette-Gaulain, K. Macouillard, G. Glasman, | Anaesth Crit Care Pain Med | 2024 |
Delayed neurocognitive recovery |
| Dexmedetomidine in Palliative Care: A Versatile New Weapon Against Delirium and Pain-Systematic Review | Tavares, T. Almeida, J. Gonçalves, E. Abelha, F. | J Palliat Med | 2024 |
agitation |
| The Effect of Dexmedetomidine as a Local Anesthetic Adjuvant for Iliac Fascia Compartment Block on Postoperative Delirium in Elderly Patients Undergoing Elective Hip Surgery | Liu, X. H. Zhang, Q. F. Zhang, X. Q. Lu, Q. W. Wu, J. H. Gao, X. H. Chen, Z. Y. | Gerontology | 2024 |
Humans |
| Serum NPTX2 as a Potential Predictive Biomarker for Postoperative Delirium in Patients with Acute Type A Aortic Dissection | Liu, W. Wang, Y. Jiang, Y. Lu, S. Zhu, J. Tian, Y. Pan, J. Xu, Z. Wang, D. | Neuropsychiatr Dis Treat | 2024 |
Nptx2 |
| Incidence and risk factors of postoperative delirium following hepatic resection: a retrospective national inpatient sample database study | Liu, R. Liu, N. Suo, S. Yang, Q. Deng, Z. Fu, W. Wang, M. | BMC Surg | 2024 |
Humans |
| Simplified Pain Management Including Fentanyl TTS in PACU Patients With Hip Fracture Surgery to Improve Patients' Well-Being: A Double-Blind Randomized Trial | Labmayr, V. Rief, M. Reinbacher, P. Gebauer, D. Smigaj, J. Sandner-Kiesling, A. Papamargaritis, V. Michaeli, K. Bornemann-Cimenti, H. Schittek, G. A. | J Perianesth Nurs | 2024 |
Humans |
| Preventive Effects of Ramelteon, Suvorexant, and Lemborexant on Delirium in Hospitalized Patients With Physical Disease: A Retrospective Cohort Study | Henmi, R. Nakamura, T. Mashimoto, M. Takase, F. Ozone, M. | J Clin Psychopharmacol | 2024 |
Sleep-inducing drugs Ramelton Suvorexant Lemborexant Delirium Hospitalized patients |
| Delirium detection in the emergency department: A diagnostic accuracy meta-analysis of history, physical examination, laboratory tests, and screening instruments | Carpenter, C. R. Lee, S. Kennedy, M. Arendts, G. Schnitker, L. Eagles, D. Mooijaart, S. Fowler, S. Doering, M. LaMantia, M. A. Han, J. H. Liu, S. W. | Acad Emerg Med | 2024 |
Geriatrics Delirium Screening accuracy Systematic Review Emergency Department |
| Association of preoperative neutrophil-to-lymphocyte ratio with the risk of postoperative delirium in elderly patients undergoing noncardiac surgery: a systematic review and meta-analysis | Zhou, B. Yu, D. D. Xu, X. Wang, J. Li, J. | Psychogeriatrics | 2024 |
neutrophil |
| Peripheral nerve block and cognitive impairment after thoracic surgery: a systematic review and meta-analysis | Zhang, Y. Liu, M. He, J. Zhang, H. Zhang, M. Li, J. | Minerva Anestesiol | 2024 |
Humans |
| Clinical characteristics of older patients with suspected or diagnosed dementia during hospitalization | Yoshino, H. Takechi, H. | Geriatr Gerontol Int | 2024 |
Humans |
| Development of an individualized model for predicting postoperative delirium in elderly patients with hepatocellular carcinoma | Yan, M. Lin, Z. Zheng, H. Lai, J. Liu, Y. Lin, Z. | Sci Rep | 2024 |
Humans |
| The relationship between intraoperative hypothermia and postoperative delirium: The PNDRFAP study | Wang, J. Zhu, L. Li, C. Lin, Y. Wang, B. Lin, X. Bi, Y. | Brain Behav | 2024 |
Humans |
| Interpretable machine learning model for early prediction of delirium in elderly patients following intensive care unit admission: a derivation and validation study | Tang, D. Ma, C. Xu, Y. | Front Med (Lausanne) | 2024 |
Icu |
| Effects of gabapentin on slow-wave sleep period in critically ill adult patients: A randomized controlled trial | Susantitapong, K. Dilokpattanamongkol, P. Sutherasan, Y. Liamsombut, S. Suthisisang, C. | Clin Transl Sci | 2024 |
Humans |
| Association between postoperative hyperactive delirium and major complications in elderly patients undergoing emergency hip fracture surgery: A large-scale cohort study | Sun, M. Chen, W. M. Wu, S. Y. Zhang, J. | Geriatr Gerontol Int | 2024 |
elderly |
| The 4AT scale for rapid detection of delirium in emergency department triage | Soler-Sanchis, A. Martínez-Arnau, F. M. Sánchez-Frutos, J. Pérez-Ros, P. | Front Med (Lausanne) | 2024 |
aged |
| Efficacy and safety of perioperative melatonin for postoperative delirium in patients undergoing surgery: a systematic review and meta-analysis | Shin, H. W. Kwak, J. S. Choi, Y. J. Kim, J. W. You, H. S. Shin, H. J. Jang, Y. K. | J Int Med Res | 2024 |
*Melatonin/therapeutic use/administration & dosage/adverse effects |
| Characterizing medical patients with delirium: A cohort study comparing ICD-10 codes and a validated chart review method | Sheehan, K. A. Shin, S. Hall, E. Mak, D. Y. F. Lapointe-Shaw, L. Tang, T. Marwaha, S. Gandell, D. Rawal, S. Inouye, S. Verma, A. A. Razak, F. | PLoS One | 2024 |
Humans |
| Postoperative Delirium and Dementia in Patients Undergoing Cardiac Surgery: A Review of Randomized Controlled Trials | Shahabi Raberi, V. Solati Kooshk Qazi, M. Zolfi Gol, A. GhorbaniNia, R. Kahourian, O. Faramarz Zadeh, R. | Galen Med J | 2023 |
Cardiac Surgery |
| The association of hemoglobin with postoperative delirium and atrial fibrillation after cardiac surgery: a retrospective sub-study | Sari, S. Brooker, J. Montalvo-Campana, M. Shehata, P. Pu, X. Insler, S. Ruetzler, K. Troianos, C. A. Turan, A. | Braz J Anesthesiol | 2024 |
Humans |
| A novel objective measure for terminal delirium: Activity scores measured by a sheet-type sensor | Otani, H. Yokomichi, N. Imai, K. Toyota, S. Yamauchi, T. Miwa, S. Yuasa, M. Okamoto, S. Kogure, T. Inoue, S. Morita, T. | J Pain Symptom Manage | 2024 |
Agitation |
| A comparison of changes in drug burden index between older inpatients who fell and people who have not fallen: A case-control study | O'Leary, C. E. T. Wilkinson, T. J. Hanger, H. C. | Australas J Ageing | 2024 |
aged |
| Characterizing Ertapenem Neurotoxicity: A Systematic Review and Experience at a Tertiary Medical Center | Mitaka, H. Hasegawa, S. Lan, K. F. Jain, R. Rakita, R. M. Pottinger, P. S. | Open Forum Infect Dis | 2024 |
carbapenems |