Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Preoperative Plasma Tau-PT217 and Tau-PT181 Are Associated With Postoperative Delirium
Authors
Liang, F. Baldyga, K. Quan, Q. Khatri, A. Choi, S. Wiener-Kronish, J. Akeju, O. Westover, B. M. Cody, K. Shen, Y. Marcantonio, E. R. Xie, Z.
Year
2022
Journal
Ann Surg
Abstract

OBJECTIVE: This study aims to identify blood biomarkers of postoperative delirium. BACKGROUND: Phosphorylated tau at threonine 217 (Tau-PT217) and 181 (Tau-PT181) are new Alzheimer disease biomarkers. Postoperative delirium is associated with Alzheimer disease. We assessed associations between Tau-PT217 or Tau-PT181 and postoperative delirium. METHODS: Of 491 patients (65 years old or older) who had a knee replacement, hip replacement, or laminectomy, 139 participants were eligible and included in the analysis. Presence and severity of postoperative delirium were assessed in the patients. Preoperative plasma concentrations of Tau-PT217 and Tau-PT181 were determined by a newly established Nanoneedle technology. RESULTS: Of 139 participants (73±6 years old, 55% female), 18 (13%) developed postoperative delirium. Participants who developed postoperative delirium had higher preoperative plasma concentrations of Tau-PT217 and Tau-PT181 than participants who did not. Preoperative plasma concentrations of Tau-PT217 or Tau-PT181 were independently associated with postoperative delirium after adjusting for age, education, and preoperative Mini-Mental State score [odds ratio (OR) per unit change in the biomarker: 2.05, 95% confidence interval (CI):1.61-2.62, P<0.001 for Tau-PT217; and OR: 4.12; 95% CI: 2.55–6.67, P<0.001 for Tau-PT181]. The areas under the receiver operating curve for predicting delirium were 0.969 (Tau-PT217) and 0.885 (Tau-PT181). The preoperative plasma concentrations of Tau-PT217 or Tau-PT181 were also associated with delirium severity [beta coefficient (β) per unit change in the biomarker: 0.14; 95% CI: 0.09-0.19, P<0.001 for Tau-PT217; and β: 0.41; 95% CI: 0.12-0.70, P=0.006 for Tau-PT181). CONCLUSIONS: Preoperative plasma concentrations of Tau-PT217 and Tau-PT181 were associated with postoperative delirium, with Tau-PT217 being a stronger indicator of postoperative delirium than Tau-PT181.

PMID

35794069

Keywords
Page(s)
Issue

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Total Records Found: 6289, showing 100 per page
TitleAuthorsJournalYearKeywords
Adverse events related to physical restraint use in intensive care units: A review of the literature Berger, S. Grzonka, P. Amacher, S. A. Hunziker, S. Frei, A. I. Sutter, R. J Intensive Med 2024

Adverse event
Complication
Delirium
Intensive care unit
Physical restraint

Managing Postoperative Delirium in Patients Receiving Head and Neck Surgery: An Educational Overview Babu, S. Kurian Sajith, B. Clin J Oncol Nurs 2024

Humans
*Delirium/prevention & control/etiology
*Head and Neck Neoplasms/surgery
*Postoperative Complications/therapy/prevention & control
Aged
Male
Female
Risk Factors
Middle Aged
Aged, 80 and over
Adult
United States
delirium
otorhinolaryngologic
patient education
surgical procedures

Risk Factors for Postoperative Delirium Severity After Deep Brain Stimulation Surgery in Parkinson's Disease Astalosch, M. Mousavi, M. Ribeiro, L. M. Schneider, G. H. Stuke, H. Haufe, S. Borchers, F. Spies, C. von Hofen-Hohloch, J. Al-Fatly, B. Ebersbach, G. Franke, C. Kühn, A. A. Kübler-Weller, D. J Parkinsons Dis 2024

Parkinson’s disease
cognition
deep brain stimulation
outcome
personalized therapy
postoperative delirium
risk prediction

A Dual-Camera Eye-Tracking Platform for Rapid Real-Time Diagnosis of Acute Delirium: A Pilot Study Al-Hindawi, A. Vizcaychipi, M. Demiris, Y. IEEE J Transl Eng Health Med 2024

Humans
*Delirium/diagnosis
Pilot Projects
Male
Female
Aged
*Eye-Tracking Technology
Prospective Studies
Middle Aged
Intensive Care Units
Aged, 80 and over
Delirium
eye-tracking
intensive care medicine

Effectiveness of nurse-led non-pharmacological interventions on outcomes of delirium in adults: A meta-analysis of randomized controlled trials Wang, J. Lu, Y. Chen, X. Wu, Y. Worldviews Evid Based Nurs 2024

adult health
delirium
meta‐analysis
nursing practice
patient outcomes

Association of blood glucose change with postoperative delirium after coronary artery bypass grafting in patients with diabetes mellitus: a study of the MIMIC-IV database Wang, F. Mei, X. Front Endocrinol (Lausanne) 2024

Humans
Male
*Coronary Artery Bypass/adverse effects
Female
*Blood Glucose/analysis
Retrospective Studies
Aged
Middle Aged
*Postoperative Complications/blood/etiology/epidemiology
*Delirium/etiology/blood/epidemiology
*Diabetes Mellitus/blood
Databases, Factual
Risk Factors
Cabg
Dm
LGMM model
Pod
blood glucose

The genetic relationship between hypotension and delirium: a Mendelian randomization study Wang, C. Wu, J. Lin, Y. Liu, Z. Liufu, N. Cao, M. Front Neurol 2024

Mendelian randomization
causal association
delirium
genetic
hypotension

Comparison of Propofol-Based Total Intravenous Anesthesia versus Volatile Anesthesia with Sevoflurane for Postoperative Delirium in Adult Coronary Artery Bypass Grafting Surgery: A Prospective Randomized Single-Blinded Study Varsha, A. V. Unnikrishnan, K. P. Saravana Babu, M. S. Raman, S. P. Koshy, T. J Cardiothorac Vasc Anesth 2024

cardiopulmonary bypass
delirium
postoperative cognitive dysfunction
propofol
sevoflurane
total intravenous anesthesia

Diagnostics and treatment of impulse control disorders, psychosis and delirium: systemic review-based recommendations - guideline "Parkinson's disease" of the German Society of Neurology Witt, K. Levin, J. van Eimeren, T. Hasan, A. Ebersbach, G. J Neurol 2024

Delirium
Guideline
Impulse control disorder
Parkinson’s disease
Psychosis

Potential mechanism of Taohong Siwu Decoction in preventing and treating postoperative delirium in intertrochanteric fracture patients based on retrospective analysis and network pharmacology Ding, Z. Yu, Z. Sun, Z. Liu, X. Chen, R. J Orthop Surg Res 2024

Humans
*Drugs, Chinese Herbal/therapeutic use/pharmacology
Retrospective Studies
*Hip Fractures/surgery
Male
Female
Aged
*Postoperative Complications/prevention & control
*Network Pharmacology
*Delirium/prevention & control/etiology
Aged, 80 and over
*Molecular Docking Simulation
Inflammation
Intertrochanteric fractures
Postoperative delirium
Taohong Siwu Decoction

Electroencephalography-Guided Anesthesia and Delirium in Older Adults After Cardiac Surgery: The ENGAGES-Canada Randomized Clinical Trial Deschamps, A. Ben Abdallah, A. Jacobsohn, E. Saha, T. Djaiani, G. El-Gabalawy, R. Overbeek, C. Palermo, J. Courbe, A. Cloutier, I. Tanzola, R. Kronzer, A. Fritz, B. A. Schmitt, E. M. Inouye, S. K. Avidan, M. S. Jama 2024

Postoperative Delirium

Anesthesia

EEG-guided anesthesia

Intraoperative EEG waveform suppression

Older Adults

Association Between Pupil Light Reflex and Delirium in Adults With Traumatic Brain Injury: Preliminary Findings Lapierre, A. Proulx, A. Gélinas, C. Dollé, S. Alexander, S. Williamson, D. Bernard, F. Arbour, C. J Neurosci Nurs 2024

Delirium

ICU Delirium

Traumatic Brain Injury

Pupillary light reflex

Postextubation delirium

 

Prevalence and risk factors of postoperative delirium in tumor patients after free flap reconstruction: A systematic review and meta-analysis of case-control studies Li, Y. Li, Z. Lv, Q. Gu, Y. Qi, Y. Li, J. Liu, Y. Ma, G. Surgery 2024

Postoperative Delirium

Flap transplantation surgery

Risk Factors

Proactive prevention measures

Systematic Review

Risk factors and risk stratification approaches for delirium screening: A Geriatric Emergency Department Guidelines 2.0 systematic review Seidenfeld, J. Lee, S. Ragsdale, L. Nickel, C. H. Liu, S. W. Kennedy, M. Acad Emerg Med 2024

Geriatrics

Delirium

Emergency Department delirium screening

Risk factors

Delirium risk scores

Systematic review

Examining the impact of permissibility hypercapnia on postoperative delirium among elderly patients undergoing thoracoscopic-laparoscopic esophagectomy: A single-center investigative study Song, J. Shao, Y. M. Zhang, G. H. Fan, B. Q. Tao, W. H. Liu, X. F. Huang, X. C. Hu, X. W. Shock 2024

Postoperative delirium

Permissive hypercapnia

ventilation

thoracic surgery

intraoperative respiration

Association between modified frailty index and postoperative delirium in patients after cardiac surgery: A cohort study of 2080 older adults Cheng, H. Ling, Y. Li, Q. Li, X. Tang, Y. Guo, J. Li, J. Wang, Z. Ming, W. K. Lyu, J. CNS Neurosci Ther 2024

Humans
Female
Male
Aged
*Cardiac Surgical Procedures/adverse effects
*Delirium/epidemiology/etiology/diagnosis
*Frailty/diagnosis/epidemiology
Aged, 80 and over
*Postoperative Complications/epidemiology/etiology/diagnosis
Retrospective Studies
Cohort Studies
Risk Factors
cardiac surgery
frailty
modified frailty index
older adults
postoperative delirium
pressure injury

Role of Intraoperative Electroencephalography in Predicting Postoperative Delirium in Patients Undergoing Cardiovascular Surgeries Al-Qudah, A. M. Sivaguru, S. Anetakis, K. Crammond, D. J. Balzer, J. R. Thirumala, P. D. Subramaniam, K. Sadhasivam, S. Shandal, V. Clin Neurophysiol 2024

Cardiopulmonary bypass
Cerebral microembolization
Cerebrovascular reserve
Intraoperative Neurophysiological Monitoring
Postoperative delirium

Differences in metalloproteinases and their tissue inhibitors in the cerebrospinal fluid are associated with delirium Aksnes, M. Schibstad, M. H. Chaudhry, F. A. Neerland, B. E. Caplan, G. Saltvedt, I. Eldholm, R. S. Myrstad, M. Edwin, T. H. Persson, K. Idland, A. V. Pollmann, C. T. Olsen, R. B. Wyller, T. B. Zetterberg, H. Cunningham, E. Watne, L. O. Commun Med (Lond) 2024

Alzheimer’s disease, Diagnostic markers, Dementia

A retrospective cohort study comparing outcomes following hip fractures in Australian indigenous patients with non-Australian indigenous patients Cheok, T. Bastick, K. George, D. Chan, T. S. Jaitly, A. Jayasekera, N. Bray, L. Poonnoose, P. M. Williams, K. ANZ J Surg 2024

hip fracture
indigenous health
mortality
orthopaedic surgery

Comparing BIS Monitoring vs. Clinical Assessment for Deep Sedation in the ICU: Effects on Delirium Reduction and Sedative Drug Doses - A randomized trial Huespe, I. Giunta, D. Acosta, K. Avila, D. Prado, E. Sanghavi, D. Carboni Bisso, I. Giannasi, S. Carini, F. C. Chest 2024

Bispectral Index,electroencephalogram-based sedation
Critically ill patients
deep sedation
delirium

Pharmacologic Management of End-of-Life Delirium: Translating Evidence into Practice Hui, D. Cheng, S. Y. Paiva, C. E. Cancers (Basel) 2024

antipsychotic agents
benzodiazepines
death
delirium
drug therapy
neoplasms
palliative care
randomized controlled trial
terminally ill

Boarding Duration in the Emergency Department and Inpatient Delirium and Severe Agitation Joseph, J. W. Elhadad, N. Mattison, M. L. P. Nentwich, L. M. Levine, S. A. Marcantonio, E. R. Kennedy, M. JAMA Netw Open 2024

Humans
*Delirium
*Emergency Service, Hospital/statistics & numerical data
Male
Female
Aged
*Psychomotor Agitation
Middle Aged
Inpatients/statistics & numerical data
Length of Stay/statistics & numerical data
Aged, 80 and over
Hospitalization/statistics & numerical data
Time Factors

Boarding Duration in the Emergency Department and Inpatient Delirium and Severe Agitation Joseph, J. W. Elhadad, N. Mattison, M. L. P. Nentwich, L. M. Levine, S. A. Marcantonio, E. R. Kennedy, M. JAMA Netw Open 2024

Humans
*Delirium
*Emergency Service, Hospital/statistics & numerical data
Male
Female
Aged
*Psychomotor Agitation
Middle Aged
Inpatients/statistics & numerical data
Length of Stay/statistics & numerical data
Aged, 80 and over
Hospitalization/statistics & numerical data
Time Factors

Perioperative Blood Transfusion and Delirium after Total Knee or Hip Arthroplasty: Retrospective Analysis Kim, S. Oh, T. K. Song, I. A. J Pers Med 2024

blood trans fusion
postoperative delirium
total hip arthroplasty
total knee arthroplasty

Randomized feasibility trial for evaluating the impact of primary nursing on delirium duration during intensive care unit stay Krüger, L. Zittermann, A. Mannebach, T. Wefer, F. Becker, T. Lohmeier, S. Lüttermann, A. von Dossow, V. Rojas, S. V. Gummert, J. Langer, G. Intensive Crit Care Nurs 2024

Delirium
Intensive care units
Nursing
Primary nursing
Randomized controlled trial

Patient recall of intensive care delirium: A qualitative investigation la Cour, K. N. Andersen-Ranberg, N. C. Mortensen, C. Poulsen, L. M. Mathiesen, O. Egerod, I. Collet, M. Acta Anaesthesiol Scand 2024

critical care
delirium
experienced delirium
intensive care unit
qualitative research

Sevoflurane multiple Wash In/Wash Out at the end of anesthesia to reduce agitation: A multicenter double-blind randomized controlled trial Landoni, G. Likhvantsev, V. V. Berikashvili, L. B. Yavorovsky, A. G. Bagdasarov, P. S. Smirnova, A. V. Serkova, T. S. Subbotin, V. V. Kadantseva, K. K. Ovezov, A. M. Yadgarov, M. Y. Yakovlev, A. A. Lamacchia, A. Gallo, L. Gracheva, N. D. Ryzhkov, P. V. Zi Contemp Clin Trials Commun 2024

Anesthesia
Non-cardiac surgery
Postoperative agitation
Randomized controlled trial
Wash in/wash out procedure

Predictive model and discriminant analysis of the development of dementia in patients with delirium in the emergency department Lupiáñez Seoane, P. Muñoz Negro, J. E. Torres Parejo, U. Gómez Jiménez, F. J. Semergen 2024

Comorbidity
Delirium
Dementia
Elderly
Emergency

Machine learning for the prediction of delirium in elderly intensive care unit patients Ma, R. Zhao, J. Wen, Z. Qin, Y. Yu, Z. Yuan, J. Zhang, Y. Wang, A. Li, C. Li, H. Chen, Y. Han, F. Zhao, Y. Sun, S. Ning, X. Eur Geriatr Med 2024

Delirium
Elderly
Intensive care unit
Machine learning
Prediction model

A Novel Preoperative Electroencephalogram-Derived Index to Predict Early Postoperative Delirium in Elderly Patients After Hip Fracture Surgeries: Development of a Prediction Model Nawan, A. Wang, G. Zhao, C. Zhang, W. Jiang, B. Feng, Y. Geriatr Orthop Surg Rehabil 2024

delirium index
elderly
electroencephalography
hip fracture
postoperative delirium
prediction model

Fixed dose ketamine for prehospital management of hyperactive delirium with severe agitation O'Brien, M. C. Kelleran, K. J. Burnett, S. J. Hausrath, K. A. Kneer, M. S. Nan, N. Ma, C. X. McCartin, R. W. Clemency, B. M. Am J Emerg Med 2024

Humans
*Ketamine/administration & dosage/therapeutic use
*Delirium/drug therapy
*Emergency Medical Services/methods
Male
Female
Middle Aged
*Psychomotor Agitation/drug therapy
Aged
Adult
Retrospective Studies
Aged, 80 and over
Anesthetics, Dissociative/administration & dosage/therapeutic use
Body Weight
Hyperactive delirium
Ketamine
Prehospital care
Sedation
Weight-based dose

Platelet Bioenergetics and Associations With Delirium and Coma in Patients With Sepsis: A Prospective Cohort Study Onyemekwu, C. A. Prendergast, N. T. Potter, K. M. Toney, N. A. Nouraie, M. S. Shiva, S. Girard, T. D. CHEST Crit Care 2024

acute brain dysfunction
bioenergetics
coma
delirium
platelet mitochondria
sepsis

Enhancing European Management of Analgesia, Sedation, and Delirium: A Multinational, Prospective, Interventional Before-After Trial Paul, N. Grunow, J. J. Rosenthal, M. Spies, C. D. Page, V. J. Hanison, J. Patel, B. Rosenberg, A. von Haken, R. Pietsch, U. Schrag, C. Waydhas, C. Schellongowski, P. Lobmeyr, E. Sander, M. Piper, S. K. Conway, D. Totzeck, A. Weiss, B. Neurocrit Care 2024

Humans
*Delirium/therapy
Male
Female
Middle Aged
Aged
Prospective Studies
Pain Management/methods
Europe
Psychomotor Agitation/therapy
Germany
Austria
Adult
Analgesia/methods
Critical Care/standards
Switzerland
Intensive Care Units
United Kingdom
Pain Measurement
Conscious Sedation
Critical care
Delirium
Delivery of health care
Intensive care units

EEG and acute confusional state at the emergency department Prud'hon, S. Amiel, H. Zanin, A. Revue, E. Kubis, N. Lozeron, P. Neurophysiol Clin 2024

Humans
*Electroencephalography/methods
Male
Female
Aged
*Confusion/diagnosis/physiopathology
*Emergency Service, Hospital
Middle Aged
Aged, 80 and over
Adult
Seizures/diagnosis/physiopathology
Status Epilepticus/diagnosis/physiopathology
Acute Disease
Encephalopathy
Epilepsy
Non-convulsive status epilepticus
Seizure
Triphasic waves

Preoperative Delirium Risk Screening in Patients Undergoing a Cardiac Surgery: Results from the Prospective Observational FINDERI Study Sadlonova, M. Hansen, N. Esselmann, H. Celano, C. M. Derad, C. Asendorf, T. Chebbok, M. Heinemann, S. Wiesent, A. Schmitz, J. Bauer, F. E. Ehrentraut, J. Kutschka, I. Wiltfang, J. Baraki, H. von Arnim, C. A. F. Am J Geriatr Psychiatry 2024

Humans
Female
Male
Aged
*Cardiac Surgical Procedures/adverse effects
*Delirium/diagnosis/epidemiology
Prospective Studies
Middle Aged
*Postoperative Complications/diagnosis/epidemiology
Risk Assessment/methods
Geriatric Assessment/methods
Risk Factors
Machine Learning
Surveys and Questionnaires
Postoperative delirium
cardiac surgery
cognition
delirium risk assessment
frailty

Predicting postoperative delirium after percutaneous transluminal angioplasty and stenting in patients with intracranial atherosclerotic stenosis Zhu, W. Shen, Y. Zhao, H. Tang, Y. Wang, X. Li, S. Neurol Res 2024

Postoperative delirium
independent risk factor
intracranial atherosclerotic stenosis
nomogram
percutaneous transluminal angioplasty and stenting

Factors contributing to sepsis-associated encephalopathy: a comprehensive systematic review and meta-analysis Zhang, Z. Guo, L. Jia, L. Duo, H. Shen, L. Zhao, H. Front Med (Lausanne) 2024

delirium
encephalopathy
meta-analysis
risk factors
sepsis

Impact of delirium intervention on cognitive load among nurses in the intensive care unit: A multi-centre cluster randomized controlled trial Zhang, S. Ji, M. Cui, W. Wei, J. Ding, S. Wu, Y. Int J Nurs Pract 2024

Humans
*Delirium/nursing
*Intensive Care Units
Female
Male
Adult
*Nursing Staff, Hospital/psychology
Middle Aged
Cognition
cognitive load
delirium
intensive care unit
intervention
nurses

Incidence and risk factors of post-operative delirium in glioma patients: A prospective cohort study in general wards Yuan, C. Cheng, Z. Liu, Y. You, Y. Wang, L. Li, D. Zhong, L. J Clin Nurs 2024

general ward
glioma
neurosurgery, risk factors
perioperative care
postoperative delirium
preoperative anxiety and depression

Effect of Morphine Used to Relieve Dyspnea Due to Heart Failure on Delirium Yoshikai, S. Ueda, M. Ikeda, K. J Palliat Med 2024

delirium
dyspnea
heart failure
morphine
palliative care

Association of Delirium with Long-Term Mortality in Critically Ill Patients with COPD Who Survived to Discharge: A Retrospective Cohort Study Xu, H. B. Xue, F. Ye, Y. Zhang, H. G. Lung 2024

Copd
Delirium
Mortality
Survival

Effect of obstructive sleep apnea on postoperative delirium: a system review and meta-analysis Xiao, Y. Li, P. J. Guo, M. Y. Cao, Y. Liang, Z. A. Sleep Breath 2024

Delirium
Meta-analysis
Obstructive sleep apnea
Positive airway pressure

A qualitative study of geriatric specialist nurses' experiences to navigate delirium in the elderly Wu, M. Chen, Z. Xu, Y. Zhao, L. Zhao, L. Xia, L. BMC Nurs 2024

Care
Delirium
Elderly
Nurse
Nursing
Qualitative

The influence of low-dose s-ketamine on postoperative delirium and cognitive function in older adults undergoing thoracic surgery Wang, Y. Ma, B. Wang, C. Wang, Y. Liu, A. Hang, L. J Cardiothorac Surg 2024

Humans
*Ketamine/administration & dosage/therapeutic use
Aged
Female
Male
Retrospective Studies
*Thoracic Surgical Procedures/adverse effects
*Postoperative Complications/prevention & control
*Delirium/prevention & control
Cognition/drug effects
Cognitive Dysfunction/prevention & control
Aged, 80 and over
Cognitive dysfunction
Neuroprotection
Older patients
Postoperative delirium
S-ketamine
Safety Profile
Thoracic surgery

Neurological diagnostic tests for patients with and without delirium: a prospective observational study Waefler, N. Abid, I. Montaut, V. Donzé, J. Zender, H. John, G. Geroscience 2024

CT scan
Delirium
Electroencephalography
Lumbar puncture
Mri

Preoperative cognitive function as a risk factor of postoperative delirium in cancer surgeries: A systematic review and meta-analysis Varpaei, H. A. Robbins, L. B. Farhadi, K. Bender, C. M. J Surg Oncol 2024

cancer survivors
cognition
cognitive reserve
neurocognitive disorders
postoperative complications
postoperative delirium

Role of oral melatonin in prevention of postoperative delirium in patients undergoing elective surgery under general anesthesia: A Randomized controlled trial Thakur, T. Saini, V. Grover, S. Samra, T. Indian J Psychiatry 2024

Anxiety
cognitive dysfunction
delirium
melatonin
surgery

Clinical characteristics of delirium in older patients with first-ever acute myocardial infarction who underwent percutaneous coronary intervention : A retrospective study Tan, J. F. Duan, L. Han, J. C. Cui, J. J. Herz 2024

Acute myocardial infarction
Cam-icu
Delirium
First-Ever

Antibiotics for delirium in older adults with pyuria or bacteriuria: A systematic review Stall, N. M. Kandel, C. Reppas-Rindlisbacher, C. Quinn, K. L. Wiesenfeld, L. MacFadden, D. R. Johnstone, J. Fralick, M. J Am Geriatr Soc 2024

antibiotics
bacteriuria
delirium
pyuria
urinary tract infection

Establishment and validation of the prediction model for postoperative delirium risk factors in older patients after total knee arthroplasty: A retrospective study Song, L. X. Qin, Y. Yang, L. Xing, D. B. Li, Y. Lei, F. Q. Wang, L. H. Medicine (Baltimore) 2024

Humans
*Arthroplasty, Replacement, Knee/adverse effects
Male
Female
Aged
Retrospective Studies
Risk Factors
Risk Assessment/methods
*Postoperative Complications/epidemiology/etiology
*Delirium/epidemiology/etiology/diagnosis
ROC Curve
Middle Aged
Nomograms
Age Factors
Aged, 80 and over
Logistic Models

Predictive value of the Naples prognostic score on postoperative delirium in the elderly with gastrointestinal tumors: a retrospective cohort study Song, C. Yu, D. Li, Y. Liu, M. Zhang, H. He, J. Li, J. BMC Geriatr 2024

Humans
Male
Female
Aged
*Gastrointestinal Neoplasms/surgery/complications
Retrospective Studies
Prognosis
*Postoperative Complications/diagnosis/epidemiology/etiology
Delirium/diagnosis/etiology/epidemiology
Predictive Value of Tests
Risk Factors
Middle Aged
ROC Curve
Elderly patients
Gastrointestinal tumors
Naples prognostic score
Postoperative delirium
Predictive markers

Effect of prophylactic corticosteroids on postoperative neurocognitive dysfunction in the adult population: An updated systematic review, meta-analysis, and trial sequential analysis of randomised controlled trials Singh, N. P. Makkar, J. K. Goel, N. Karamchandani, K. Singh, M. Singh, P. M. Indian J Anaesth 2024

Corticosteroids
delayed neurocognitive recovery
delirium
dexamethasone
meta-analysis
post-operative neurocognitive dysfunction
postoperative cognitive dysfunction
systematic review
trial sequential analysis

Usefulness of the 4A's test for detecting delirium in critically ill patients: a multicenter prospective observation study Sim, J. K. Chung, K. Chung, C. R. Lee, J. Hwang, S. Y. Lee, Y. S. Intern Emerg Med 2024

Critical illness
Dsm-5
Delirium
Diagnosis
Intensive Care Units

Incidence of Postoperative Delirium among Elderly Patients after Elective Surgeries under Anesthesia in the Charity Services of the Philippine General Hospital Hermoso, R. M. L. Cruz, P. L. O. Acta Med Philipp 2024

elderly
incidence
postoperative delirium

Registered nurses' experiences of caring for patients with hypoactive delirium after cardiac surgery - A qualitative study Hallberg Kristensen, A. Nymark, C. Stenman, M. Falk, A. Intensive Crit Care Nurs 2024

Cardiac surgical procedures
Focus groups
Hypoactive delirium
Nurses
Patient care

Determinants of delirium in elderly in-patients in a general ward setting in a teaching hospital: A case control study Geetha, J. Babu, H. George, C. Ind Psychiatry J 2024

Delirium
determinants
elderly
general wards
inpatients

Incidence and risk factors of delirium following brain tumor resection: A retrospective National Inpatient Sample database study Fu, W. Li, Y. Liu, R. Li, J. World Neurosurg 2024

Brain tumor
Delirium
National Inpatient Sample
Resection
Risk factors

Prolonged hourly neurological examinations are associated with increased delirium and no discernible benefit in mild/moderate geriatric traumatic brain injury Fonseca, R. A. Canas, M. Diaz, L. Aldana, J. A. Afzal, H. De Filippis, A. Del Toro, D. Day, A. McCarthy, J. Stansfield, K. Bochicchio, G. V. Niziolek, G. Kranker, L. M. Rosengart, M. R. Hoofnagle, M. Leonard, J. J Trauma Acute Care Surg 2024

Humans
*Delirium/diagnosis/etiology/epidemiology
Male
*Brain Injuries, Traumatic/complications/diagnosis
Female
Retrospective Studies
Aged
*Neurologic Examination/methods
*Glasgow Coma Scale
*Intensive Care Units/statistics & numerical data
Time Factors
Aged, 80 and over
Middle Aged
Risk Factors

Nursing Intervention to Prevent and Manage Delirium in Critically Ill Patients: A Scoping Review Fernandes, F. Santos, M. Anacleto, A. M. Jerónimo, C. Ferreira, Ó Baixinho, C. L. Healthcare (Basel) 2024

adult
critical care
critically ill
delirium
intensive care unit
nursing care

Intraoperative electroencephalogram features related to frailty in older patients: an exploratory prospective observational study Fang, P. P. Zhang, H. W. Hao, X. X. Shang, Z. X. Li, J. Liu, X. S. J Clin Monit Comput 2024

Humans
Male
Prospective Studies
Aged
*Electroencephalography/methods
*Frailty/diagnosis
*Frail Elderly
Female
*Anesthesia, General
Aged, 80 and over
Risk Factors
Postoperative Complications
Monitoring, Intraoperative/methods
Propofol/administration & dosage
Brain/physiopathology
Delirium/diagnosis
Intraoperative Neurophysiological Monitoring/methods
Electroencephalogram
Frailty
Postoperative delirium
Propofol

Managing Delirium in the Emergency Department: An Updated Narrative Review Ehrlich, A. Oh, E. S. Ahmed, S. Curr Geriatr Rep 2024

Confusion
Delirium
Emergency Room
Management

A narrative review of the development and performance characteristics of electronic delirium-screening tools Eeles, E. Tran, D. D. Boyd, J. Tronstad, O. Teodorczuk, A. Flaws, D. Fraser, J. F. Dissanayaka, N. Aust Crit Care 2024

*Delirium/diagnosis
Humans
*Mass Screening/methods
*Psychometrics
Computers
Delirium
Diagnosis
Handheld
Mobile applications
Smartphone

The Role of Neutrophil-to-Lymphocyte Ratio (NLR) in Urosepsis-Associated Delirium Dragoescu, A. N. Padureanu, V. Stanculescu, A. D. Chiutu, L. Padureanu, R. Andrei, M. Radu, M. A. Mitroi, G. Dragoescu, P. O. Cureus 2024

diagnostic
intensive care unit
management
neutrophil-to-lymphocyte ratio (nlr)
prevention
sepsis
septic shock [ss]
urosepsis-associated delirium

Does Melatonin Decrease the Use of As-Needed Antipsychotics or Benzodiazepines in Noncritically Ill Hospitalized Patients? A Multicenter Retrospective Cohort Study Dobry, P. Poparad-Stezar, A. Bacon, O. Boji, S. Giuliano, C. J Integr Complement Med 2024

Humans
*Melatonin/administration & dosage/therapeutic use
Retrospective Studies
Male
Female
*Antipsychotic Agents/administration & dosage/therapeutic use
Middle Aged
Aged
*Benzodiazepines/administration & dosage/therapeutic use
*Delirium/drug therapy/epidemiology/prevention & control
Zolpidem/therapeutic use/administration & dosage
Adult
Hospitalization/statistics & numerical data
Hypnotics and Sedatives/administration & dosage/therapeutic use
Aged, 80 and over
antipsychotics
benzodiazepines
delirium
melatonin
zolpidem

Comparison of the frailty index and frailty phenotype and their associations with postoperative delirium incidence and severity Deiner, S. G. Marcantonio, E. R. Trivedi, S. Inouye, S. K. Travison, T. G. Schmitt, E. M. Hshieh, T. Fong, T. G. Ngo, L. H. Vasunilashorn, S. M. J Am Geriatr Soc 2024

Humans
Female
Male
Aged
Incidence
*Delirium/epidemiology/diagnosis
Prospective Studies
*Postoperative Complications/epidemiology
*Phenotype
*Frailty/epidemiology/diagnosis
Aged, 80 and over
Frail Elderly/statistics & numerical data
Severity of Illness Index
Geriatric Assessment/methods
Elective Surgical Procedures/adverse effects
Risk Factors
delirium
frailty index
frailty phenotype
surgery

Frailty index and risk of delirium in hospitalized patients: a two-sample Mendelian randomization study Chen, Y. Feng, F. Li, Q. Guo, H. Zhang, L. Liu, J. Front Med (Lausanne) 2024

Mendelian randomization study
delirium
frailty index
intensive care
nursing care

Enhancing hospice care with psychological support and a nomogram to predict delirium in patients with advanced solid tumors Chen, J. Huan, J. Chen, C. Xu, W. Jia, A. Am J Cancer Res 2024

Hospice care
advanced cancer
delirium
dysphoria
psychological interventions

The influence of sleep disorders on perioperative neurocognitive disorders among the elderly: A narrative review Chen, C. Zhai, R. X. Lan, X. Yang, S. F. Tang, S. J. Xiong, X. L. He, Y. X. Lin, J. F. Feng, J. R. Chen, D. X. Shi, J. Ibrain 2024

insomnia
perioperative neurocognitive disorders
postoperative cognitive dysfunction
postoperative delirium
sleep disorders

Prevalence of preoperative depression and adverse outcomes in older patients undergoing elective surgery: A systematic review and meta-analysis Chen, A. An, E. Yan, E. Saripella, A. Khullar, A. Misati, G. Alhamdah, Y. Englesakis, M. Mah, L. Tartaglia, C. Chung, F. J Clin Anesth 2024

Delirium, older patients
Depression
Preoperative assessment
Surgery
Systematic review and meta-analysis

Antipsychotic medications and severe sepsis in schizophrenia: A nested case-control study Chang, C. W. Chen, W. Y. Chen, P. Y. Pan, C. H. Su, S. S. Tsai, S. Y. Chen, C. C. Kuo, C. J. Aust N Z J Psychiatry 2024

Sepsis
antipsychotics
nested case–control study
nonpsychiatric medications
physical illnesses
risk factors
schizophrenia

Selection of knowledge translation strategies to implement best practices on nonpharmacological prevention of delirium in intensive care unit Boivin, A. Bérubé, M. Rech Soins Infirm 2024

Humans
*Delirium/prevention & control/nursing
*Critical Care/methods/standards
Translational Research, Biomedical/standards/methods
Intensive Care Units/standards
Practice Guidelines as Topic/standards
delirium
intensive care unit
prevention
best practice analysis
organizational innovation

Barriers to healthcare professionals recognizing and managing delirium in older adults during a hospital stay: A mixed-methods systematic review Bianchi, L. A. Harris, R. Fitzpatrick, J. M. J Adv Nurs 2024

Humans
*Delirium/diagnosis
Aged
Health Personnel/psychology
Aged, 80 and over
Hospitalization
Female
Male
delirium
health professionals
hospital
management
nurses
older people
recognition
screening
systematic review

Burden of delirium on mortality and healthcare resource utilization in geriatric patients hospitalized for inflammatory bowel disease Aldiabat, M. Aleyadeh, W. Rana, T. Ta'ani, O. A. Alahmad, M. Ayoub, M. Jaber, F. Obeidat, A. Numan, L. Manvar, A. Alhuneafat, L. Proc (Bayl Univ Med Cent) 2024

Geriatrics
inflammatory bowel disease
outcomes research

Prophylactic Minocycline for Delirium in Critically Ill Patients: A Randomized Controlled Trial Dal-Pizzol, F. Coelho, A. Simon, C. S. Michels, M. Corneo, E. Jeremias, A. Damásio, D. Ritter, C. Chest 2024

Humans
*Delirium/prevention & control
*Minocycline/therapeutic use/administration & dosage
Male
Female
*Critical Illness
Middle Aged
Aged
Double-Blind Method
Intensive Care Units
Hospital Mortality
Incidence
Neuroprotective Agents/therapeutic use/administration & dosage
Anti-Bacterial Agents/therapeutic use
Biomarkers/blood
Length of Stay/statistics & numerical data
brain dysfunction
delirium
inflammation
microglia
minocycline

Clinical Significance of the Prognostic Nutritional Index in Predicting Delirium among Critically Ill Patients: A Retrospective Cohort Study Xu, F. Zhong, X. Crit Care Res Pract 2024

Delirium

Prognostic Nutrition Index

ICU

Critically ill patients

MIMIC IV

Impact of Continuous Infusion Ketamine Compared to Continuous Infusion Benzodiazepines on Delirium in the Intensive Care Unit Vollmer, N. J. Wieruszewski, E. D. Nei, A. M. Mara, K. C. Rabinstein, A. A. Brown, C. S. J Intensive Care Med 2024

benzodiazepines
delirium
ketamine
pharmacology
sedation

Preoperative ketamine administration for prevention of postoperative neurocognitive disorders after major orthopedic surgery in elderly patients: A multicenter randomized blinded placebo-controlled trial Verdonk, F. Lambert, P. Gakuba, C. Nelson, A. C. Lescot, T. Garnier, F. Constantin, J. M. Saurel, D. Lasocki, S. Rineau, E. Diemunsch, P. Dreyfuss, L. Tavernier, B. Bezu, L. Josserand, J. Mebazaa, A. Coroir, M. Nouette-Gaulain, K. Macouillard, G. Glasman, Anaesth Crit Care Pain Med 2024

Delayed neurocognitive recovery
Frailty
Ketamine
Orthopaedic Surgery
Postoperative neurocognitive disorder

Dexmedetomidine in Palliative Care: A Versatile New Weapon Against Delirium and Pain-Systematic Review Tavares, T. Almeida, J. Gonçalves, E. Abelha, F. J Palliat Med 2024

agitation
alpha-adrenergic
confusion
delirium
dexmedetomidine
pain
palliative medicine
sedation
terminal care

The Effect of Dexmedetomidine as a Local Anesthetic Adjuvant for Iliac Fascia Compartment Block on Postoperative Delirium in Elderly Patients Undergoing Elective Hip Surgery Liu, X. H. Zhang, Q. F. Zhang, X. Q. Lu, Q. W. Wu, J. H. Gao, X. H. Chen, Z. Y. Gerontology 2024

Humans
*Dexmedetomidine/administration & dosage
Male
Aged
Female
*Anesthetics, Local/administration & dosage
*Nerve Block/methods
*Ropivacaine/administration & dosage
*Elective Surgical Procedures/adverse effects/methods
Fascia
Aged, 80 and over
Emergence Delirium/prevention & control/epidemiology
Postoperative Complications/prevention & control/epidemiology
Hip/surgery
Arthroplasty, Replacement, Hip/adverse effects/methods
Analgesia
Dexmedetomidine
Fascia iliaca compartment block
Hip surgery
Postoperative delirium

Serum NPTX2 as a Potential Predictive Biomarker for Postoperative Delirium in Patients with Acute Type A Aortic Dissection Liu, W. Wang, Y. Jiang, Y. Lu, S. Zhu, J. Tian, Y. Pan, J. Xu, Z. Wang, D. Neuropsychiatr Dis Treat 2024

Nptx2
acute type a aortic dissection
biomarker
postoperative delirium

Incidence and risk factors of postoperative delirium following hepatic resection: a retrospective national inpatient sample database study Liu, R. Liu, N. Suo, S. Yang, Q. Deng, Z. Fu, W. Wang, M. BMC Surg 2024

Humans
Male
Female
Middle Aged
Risk Factors
*Hepatectomy/adverse effects
Aged
Retrospective Studies
*Postoperative Complications/epidemiology/etiology
Incidence
*Delirium/epidemiology/etiology
*Databases, Factual
United States/epidemiology
Adult
Comorbidities
Complications
Hepatic resection
Postoperative delirium

Simplified Pain Management Including Fentanyl TTS in PACU Patients With Hip Fracture Surgery to Improve Patients' Well-Being: A Double-Blind Randomized Trial Labmayr, V. Rief, M. Reinbacher, P. Gebauer, D. Smigaj, J. Sandner-Kiesling, A. Papamargaritis, V. Michaeli, K. Bornemann-Cimenti, H. Schittek, G. A. J Perianesth Nurs 2024

Humans
Double-Blind Method
*Hip Fractures/surgery/complications
*Fentanyl/administration & dosage
Male
Female
Aged
*Pain Management/methods/statistics & numerical data/standards
*Pain, Postoperative/drug therapy
*Analgesics, Opioid/administration & dosage
Aged, 80 and over
Middle Aged
Acetaminophen/administration & dosage/therapeutic use
Postanesthesia Nursing/methods/standards
Pirinitramide/administration & dosage
Recovery Room/statistics & numerical data
Pacu
analgesia
delirium
hip fracture
pain
well-being

Preventive Effects of Ramelteon, Suvorexant, and Lemborexant on Delirium in Hospitalized Patients With Physical Disease: A Retrospective Cohort Study Henmi, R. Nakamura, T. Mashimoto, M. Takase, F. Ozone, M. J Clin Psychopharmacol 2024

Sleep-inducing drugs

Ramelton

Suvorexant

Lemborexant

Delirium

Hospitalized patients

Delirium detection in the emergency department: A diagnostic accuracy meta-analysis of history, physical examination, laboratory tests, and screening instruments Carpenter, C. R. Lee, S. Kennedy, M. Arendts, G. Schnitker, L. Eagles, D. Mooijaart, S. Fowler, S. Doering, M. LaMantia, M. A. Han, J. H. Liu, S. W. Acad Emerg Med 2024

Geriatrics

Delirium

Screening accuracy

Systematic Review

Emergency Department

Association of preoperative neutrophil-to-lymphocyte ratio with the risk of postoperative delirium in elderly patients undergoing noncardiac surgery: a systematic review and meta-analysis Zhou, B. Yu, D. D. Xu, X. Wang, J. Li, J. Psychogeriatrics 2024

neutrophil
neutrophil‐to‐lymphocyte ratio
postoperative delirium

Peripheral nerve block and cognitive impairment after thoracic surgery: a systematic review and meta-analysis Zhang, Y. Liu, M. He, J. Zhang, H. Zhang, M. Li, J. Minerva Anestesiol 2024

Humans
*Nerve Block
*Thoracic Surgical Procedures/adverse effects
*Postoperative Complications/epidemiology/etiology/prevention & control
Cognitive Dysfunction/etiology
Postoperative Cognitive Complications/etiology/epidemiology/prevention & control

Clinical characteristics of older patients with suspected or diagnosed dementia during hospitalization Yoshino, H. Takechi, H. Geriatr Gerontol Int 2024

Humans
Female
Male
*Dementia/diagnosis/epidemiology
*Hospitalization
Aged
Aged, 80 and over
Japan/epidemiology
Risk Factors
Delirium/diagnosis/epidemiology
Body Mass Index
Geriatric Assessment/methods
Comorbidity
dementia
hospitalized patient
older

Development of an individualized model for predicting postoperative delirium in elderly patients with hepatocellular carcinoma Yan, M. Lin, Z. Zheng, H. Lai, J. Liu, Y. Lin, Z. Sci Rep 2024

Humans
*Carcinoma, Hepatocellular/surgery
*Liver Neoplasms/surgery
Aged
Female
Male
*Postoperative Complications/etiology
*Nomograms
*Delirium/etiology/diagnosis
Risk Factors
*ROC Curve
Aged, 80 and over
Retrospective Studies
Hepatectomy/adverse effects

The relationship between intraoperative hypothermia and postoperative delirium: The PNDRFAP study Wang, J. Zhu, L. Li, C. Lin, Y. Wang, B. Lin, X. Bi, Y. Brain Behav 2024

Humans
Male
Female
Middle Aged
Aged
*Hypothermia/epidemiology
*Postoperative Complications/epidemiology/etiology
*Delirium/etiology/epidemiology
*Intraoperative Complications/epidemiology/etiology
Anesthesia, General/adverse effects
Risk Factors
Digestive System Surgical Procedures/adverse effects
Incidence
Adult
cognitive function
intraoperative hypothermia
mediation analysis
postoperative delirium
risk factor

Interpretable machine learning model for early prediction of delirium in elderly patients following intensive care unit admission: a derivation and validation study Tang, D. Ma, C. Xu, Y. Front Med (Lausanne) 2024

Icu
delirium
elderly
explainable machine learning
prediction model

Effects of gabapentin on slow-wave sleep period in critically ill adult patients: A randomized controlled trial Susantitapong, K. Dilokpattanamongkol, P. Sutherasan, Y. Liamsombut, S. Suthisisang, C. Clin Transl Sci 2024

Humans
*Gabapentin/therapeutic use/administration & dosage
*Critical Illness
Male
Female
Middle Aged
Aged
Prospective Studies
*Sleep, Slow-Wave/drug effects
Adult
Intensive Care Units
Insulin-Like Growth Factor I/metabolism/analysis
Sleep Deprivation/drug therapy/physiopathology
Treatment Outcome

Association between postoperative hyperactive delirium and major complications in elderly patients undergoing emergency hip fracture surgery: A large-scale cohort study Sun, M. Chen, W. M. Wu, S. Y. Zhang, J. Geriatr Gerontol Int 2024

elderly
hip fracture
postoperative hyperactive delirium
postoperative major complications
propensity score matching

The 4AT scale for rapid detection of delirium in emergency department triage Soler-Sanchis, A. Martínez-Arnau, F. M. Sánchez-Frutos, J. Pérez-Ros, P. Front Med (Lausanne) 2024

aged
data accuracy
delirium
emergency service hospital
triage

Efficacy and safety of perioperative melatonin for postoperative delirium in patients undergoing surgery: a systematic review and meta-analysis Shin, H. W. Kwak, J. S. Choi, Y. J. Kim, J. W. You, H. S. Shin, H. J. Jang, Y. K. J Int Med Res 2024

*Melatonin/therapeutic use/administration & dosage/adverse effects
Humans
*Postoperative Complications/prevention & control/drug therapy
*Delirium/prevention & control/drug therapy
Perioperative Care/methods
Indenes/therapeutic use/adverse effects/administration & dosage
Randomized Controlled Trials as Topic
Length of Stay
Treatment Outcome
Hospital Mortality
Delirium
melatonin
meta-analysis
perioperative treatment
postoperative
ramelteon
surgery

Characterizing medical patients with delirium: A cohort study comparing ICD-10 codes and a validated chart review method Sheehan, K. A. Shin, S. Hall, E. Mak, D. Y. F. Lapointe-Shaw, L. Tang, T. Marwaha, S. Gandell, D. Rawal, S. Inouye, S. Verma, A. A. Razak, F. PLoS One 2024

Humans
*Delirium/diagnosis/epidemiology
Male
Female
*International Classification of Diseases
Aged
Retrospective Studies
Middle Aged
Aged, 80 and over
Ontario/epidemiology
Hospitalization
Cohort Studies

Postoperative Delirium and Dementia in Patients Undergoing Cardiac Surgery: A Review of Randomized Controlled Trials Shahabi Raberi, V. Solati Kooshk Qazi, M. Zolfi Gol, A. GhorbaniNia, R. Kahourian, O. Faramarz Zadeh, R. Galen Med J 2023

Cardiac Surgery
Dementia
Postoperative Complications

The association of hemoglobin with postoperative delirium and atrial fibrillation after cardiac surgery: a retrospective sub-study Sari, S. Brooker, J. Montalvo-Campana, M. Shehata, P. Pu, X. Insler, S. Ruetzler, K. Troianos, C. A. Turan, A. Braz J Anesthesiol 2024

Humans
*Atrial Fibrillation
Aged
*Cardiac Surgical Procedures
Female
Middle Aged
Male
*Hemoglobins/analysis/metabolism
*Delirium/etiology/epidemiology
*Postoperative Complications/epidemiology/etiology
*Anemia
Retrospective Studies
Aged, 80 and over
Adult
Adolescent
Young Adult
Anemia
Atrial fibrillation
Cardiac surgery
Delirium
General anesthesia

A novel objective measure for terminal delirium: Activity scores measured by a sheet-type sensor Otani, H. Yokomichi, N. Imai, K. Toyota, S. Yamauchi, T. Miwa, S. Yuasa, M. Okamoto, S. Kogure, T. Inoue, S. Morita, T. J Pain Symptom Manage 2024

Agitation
Delirium
Nemuri SCAN
Palliative Care
Richmond Agitation-Sedation Scale (RASS)
Terminal illness

A comparison of changes in drug burden index between older inpatients who fell and people who have not fallen: A case-control study O'Leary, C. E. T. Wilkinson, T. J. Hanger, H. C. Australas J Ageing 2024

aged
anticholinergics
sedatives

Characterizing Ertapenem Neurotoxicity: A Systematic Review and Experience at a Tertiary Medical Center Mitaka, H. Hasegawa, S. Lan, K. F. Jain, R. Rakita, R. M. Pottinger, P. S. Open Forum Infect Dis 2024

carbapenems
ertapenem
neurotoxicity
systematic review
β-lactams