What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Integrated Multi-Omics Analysis of Cerebrospinal Fluid in Postoperative Delirium
- Authors
- Tripp, B. A. Dillon, S. T. Yuan, M. Asara, J. M. Vasunilashorn, S. M. Fong, T. G. Inouye, S. K. Ngo, L. H. Marcantonio, E. R. Xie, Z. Libermann, T. A. Otu, H. H.
- Year
- 2024
- Journal
- Biomolecules
- Abstract
Preoperative risk biomarkers for delirium may aid in identifying high-risk patients and developing intervention therapies, which would minimize the health and economic burden of postoperative delirium. Previous studies have typically used single omics approaches to identify such biomarkers. Preoperative cerebrospinal fluid (CSF) from the Healthier Postoperative Recovery study of adults ≥ 63 years old undergoing elective major orthopedic surgery was used in a matched pair delirium case-no delirium control design. We performed metabolomics and lipidomics, which were combined with our previously reported proteomics results on the same samples. Differential expression, clustering, classification, and systems biology analyses were applied to individual and combined omics datasets. Probabilistic graph models were used to identify an integrated multi-omics interaction network, which included clusters of heterogeneous omics interactions among lipids, metabolites, and proteins. The combined multi-omics signature of 25 molecules attained an AUC of 0.96 [95% CI: 0.85-1.00], showing improvement over individual omics-based classification. We conclude that multi-omics integration of preoperative CSF identifies potential risk markers for delirium and generates new insights into the complex pathways associated with delirium. With future validation, this hypotheses-generating study may serve to build robust biomarkers for delirium and improve our understanding of its pathophysiology.
- PMID
PMID: 39199312
PMCID: PMC11352186
- Keywords
Humans
*Delirium/cerebrospinal fluid/metabolism
Aged
Female
Male
*Biomarkers/cerebrospinal fluid
*Metabolomics/methods
*Postoperative Complications/cerebrospinal fluid
Middle Aged
Proteomics/methods
Lipidomics
Aged, 80 and over
Case-Control Studies
Multiomics
delirium
metabolomics
multi-omics
proteomics
risk factors
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| The use of peripheral nerve block decrease incidence of postoperative cognitive dysfunction following orthopedic surgery: A systematic review and meta-analysis | Deng, L. Jiao, B. Cai, J. Xu, X. Chen, M. Yan, C. Zhu, T. Liu, J. Ma, D. Chen, C. | BMC Anesthesiol | 2024 |
Humans |
| Optimizing anesthesia management based on early identification of electroencephalogram burst suppression risk in non-cardiac surgery patients: a visualized dynamic nomogram | Chen, J. Li, W. Chen, Q. Zhou, Z. Chen, C. Hu, Y. Si, Y. Zou, J. | Ann Med | 2024 |
Humans |
| Routine cognitive screening for older people undergoing major elective surgery: Benefits, risks and costs | Chan, L. K. Chuan, A. Berney, C. R. Chan, D. K. | Anaesth Intensive Care | 2024 |
Humans |
| Prevalence and risk factors of subsyndromal delirium in ICU: A systematic review and meta-analysis | Ma, X. Cheng, H. Zhao, Y. Zhu, Y. | Intensive Crit Care Nurs | 2024 |
Intensive care unit |
| Predisposing and precipitating factors for the development of postoperative delirium in critically ill patients in a university intensive care unit | Marques, D. M. Alves, Ddsb Vernaglia, T. V. C. | Rev Lat Am Enfermagem | 2024 |
Humans |
| Diagnostic test accuracy of screening tools for the detection of neurocognitive disorders in older adults post-trauma: A protocol for a systematic review | Merriman, N. A. Walsh, M. E. O'Regan, N. Carrigan, M. Hickey, P. Brent, L. Blake, C. | HRB Open Res | 2024 |
cognition |
| How much risk does delirium represent for the development of dementia?: Retrospective cohort study from over 260,000 patients record in a solitary institution | Minami, H. Toyoda, K. Hata, T. Nishihara, M. Neo, M. Nishida, K. Kanazawa, T. | Front Psychiatry | 2024 |
cognitive decline |
| Effectiveness of the ABCDEF Bundle to Manage and Prevent Delirium: Pre- and Postintervention Quasi-Experimental Study | Nagy Nagm Eldean, T. Hassan Bakri, M. Anwar Abdel Aziz, M. Shalaby Khalaf, G. | Crit Care Nurs Q | 2024 |
Humans |
| C reactive protein albumin ratio as a new predictor of postoperative delirium after cholecystectomy for acute cholecystitis | Nakatake, R. Funatsuki, T. Koshikawa, Y. Okuyama, T. Ishizaki, M. Takekita, Y. Kato, M. Kitade, H. | Sci Rep | 2024 |
Humans |
| The impact of preoperative psychiatric intervention for postoperative delirium after major oral and maxillofacial surgery with free flap reconstruction | Nitta, Y. Sanuki, T. Sugino, S. Sugimoto, M. Kido, K. | J Stomatol Oral Maxillofac Surg | 2024 |
Free flap reconstruction |
| Impact of beta-blocker usage on delirium in patients with sepsis in ICU: a cross-sectional study | Ouyang, H. Wang, X. Deng, D. Wang, Q. Yu, Y. | Front Med (Lausanne) | 2024 |
ICU stay |
| Utilization of NIRS Monitor to Compare the Regional Cerebral Oxygen Saturation Between Dexmedetomidine and Propofol Sedation in Mechanically Ventilated Critically ill Patients with Sepsis- A Prospective Randomized Control Trial | Patidar, A. K. Khanna, P. Kashyap, L. Ray, B. R. Maitra, S. | J Intensive Care Med | 2024 |
delirium |
| Postoperative Delirium and Neurocognitive Disorders: A Comprehensive Review of Pathophysiology, Risk Factors, and Management Strategies | Paunikar, S. Chakole, V. | Cureus | 2024 |
cognitive impairment |
| Preoperative serum ferritin as a biomarker for predicting delirium among elderly patients receiving non-cardiac surgery: a retrospective cohort study | Ruan, X. Li, Y. Yuan, M. Li, H. Lou, J. Liu, Y. Cao, J. Ma, Y. Mi, W. Zhang, X. | Transl Psychiatry | 2024 |
Humans |
| Circadian disturbances, anxiety and motor disturbances differentiate delirium superimposed on dementia from dementia-only | Schnorr, T. Fleiner, T. Trumpf, R. Prüter-Schwarte, C. Fanselow, J. Zijlstra, W. Haussermann, P. | Front Psychiatry | 2024 |
acute hospital |
| Real-World Adherence to a Delirium Screening Test Administered by Nurses and Medical Staff during Routine Patient Care | Soboh, R. Rotfeld, M. Gino-Moor, S. Jiries, N. Ginsberg, S. Oliven, R. | Brain Sci | 2024 |
Radar |
| Dexmedetomidine for Postoperative Delirium Prevention in the Older Adult: An Integrative Review | Strada, A. L. Tevay, A. Scoggins, M. Gonzalez, K. | Aana j | 2024 |
Humans |
| Improving delirium assessments in acute senior health: A quality improvement project for care of the older person | Taylor, C. Peakman, G. Mackinnon, L. Mohamadzade, N. Han, W. Mackie, L. Gandhi, J. Mitchell, O. Bateman-Champain, C. Hetherington, J. Belarbi, F. Alg, G. | BMC Geriatr | 2024 |
Alzheimer’s disease |
| Postoperative delirium among elderly elective orthopedic patients in Addis Ababa Ethiopia: a multicentere longitudinal study | Tekletsadik, Y. A. Workineh, S. A. Gesso, A. S. Hirbo, H. S. | BMC Anesthesiol | 2024 |
Humans |
| Effect of optimizing cerebral oxygen saturation on postoperative delirium in older patients undergoing one-lung ventilation for thoracoscopic surgery | Teng, P. Liu, H. Xu, D. Feng, X. Liu, M. Wang, Q. | J Int Med Res | 2024 |
Humans |
| Persistent delirium is associated with cerebrospinal fluid markers of neuronal injury | Tsui, A. Johnstone, B. Heslegrave, A. Zetterberg, H. Watne, L. O. Neerland, B. E. Krogseth, M. Cunningham, C. MacLullich, A. Muniz Terrera, G. Davis, D. Caplan, G. | Brain Commun | 2024 |
CSF biomarkers |
| A Retrospective Study Establishing a Nomogram Predictive Model for Postoperative High-Activity Delirium After Non-Cardiac Surgery | Tu, Y. Du, W. Pan, Y. Zhang, X. Mo, Y. Sun, C. Wang, J. | Neuropsychiatr Dis Treat | 2024 |
Pacu |
| Safe Landing: Feasibility and Safety of Operating Room Extubation in Minimally Invasive Cardiac Valve Surgery | Wang, C. C. DeBose-Scarlett, A. Irlmeier, R. Ye, F. Siegrist, K. Shah, A. S. Kingeter, M. | J Cardiothorac Vasc Anesth | 2024 |
intubation duration |
| Intraoperative hypotension and postoperative delirium in elderly male patients undergoing laryngectomy: a single-center retrospective cohort study | Wang, Y. Chen, K. Ye, M. Shen, X. | Braz J Anesthesiol | 2024 |
Hypotension |
| Perioperative Risk Factors for Postoperative Delirium in Non-Dementia Older Patients after Non-Cardiac Surgery and Anesthesia: A Prospective Study | Wattanaboot, N. Kuawatcharawong, W. Permsakmesub, P. | Ann Geriatr Med Res | 2024 |
Postoperative delirium |
| Association of preoperative frailty with risk of postoperative delirium in older patients undergoing craniotomy: a prospective cohort study | Wei, L. Liu, M. Zhang, S. Chen, Y. Wu, M. Chen, X. Liu, J. He, Y. Yang, X. Xian, J. | BMC Surg | 2024 |
Humans |
| Geriatric nutritional risk index predicts postoperative delirium in elderly: A meta-analysis | Xie, S. Wu, Q. | Saudi Med J | 2024 |
Humans |
| Intensive care unit interventions to promote sleep and circadian biology in reducing incident delirium: a scoping review | Wilcox, M. E. Burry, L. Englesakis, M. Coman, B. Daou, M. van Haren, F. M. Ely, E. W. Bosma, K. J. Knauert, M. P. | Thorax | 2024 |
Humans |
| Theory-based and evidence-based nursing interventions for the prevention of ICU-acquired weakness in the intensive care unit: A systematic review | Xu, Q. Tan, J. Wang, Y. Tang, M. | PLoS One | 2024 |
Humans |
| Transradial versus transfemoral access for middle meningeal artery embolization: Choice of the access route considering delirium in the elderly | Yamamoto, M. Fujiwara, G. Takezawa, H. Uzura, Y. Yokoya, S. Oka, H. | Surg Neurol Int | 2024 |
Chronic subdural hematoma |
| The effect of perioperative dexmedetomidine on postoperative delirium in adult patients undergoing cardiac surgery with cardiopulmonary bypass: a systematic review and meta-analysis of randomized controlled trials | Zhuang, X. Fu, L. Luo, L. Dong, Z. Jiang, Y. Zhao, J. Yang, X. Hei, F. | BMC Anesthesiol | 2024 |
Adult |
| Incidence and associated factors of delirium after primary total joint arthroplasty in elderly patients: A systematic review and meta-analysis | Zhang, Y. Yu, Y. Han, Z. Diao, L. Zhao, R. Liu, J. Luo, Y. Wu, H. Yang, Y. | Medicine (Baltimore) | 2024 |
Aged |
| The effect of two different modes of anaesthesia maintenance on postoperative delirium in elderly patient with low preoperative mini-cog score | Duran, H. T. Kızılkaya, M. Aydinli, A. Osmantevfik, S. Taştan, S. Kılınç, OÖ Pirhan, Y. | BMC Anesthesiol | 2024 |
Aged |
| Extracellular Vesicle MicroRNAs as Predictive Biomarkers in Postoperative Delirium After Spine Surgery: Preliminary Study | Cho, Y. E. Kim, J. Vorn, R. Cho, H. Baek, W. Park, H. Yun, S. Kim, H. S. Cashion, A. K. Gill, J. Koo, B. N. Lee, H. | J Gerontol A Biol Sci Med Sci | 2024 |
Humans |
| Exploring the role of calf circumference as a predisposing factor for intra-hospital delirium: investigating potential gender differences: revealing potential gender variances | Ceolin, C. Papa, M. V. Simonato, C. Cazzavillan, S. Vergadoro, M. Trapella, G. S. Sermasi, R. De Rui, M. Noale, M. Zanforlini, B. M. Curreri, C. Bertocco, A. Devita, M. Sergi, G. Coin, A. | BMC Geriatr | 2024 |
Humans |
| Neurophysiological patterns reflecting vulnerability to delirium subtypes: a resting-state EEG and event-related potential study | Boord, M. S. Feuerriegel, D. Coussens, S. W. Davis, D. H. J. Psaltis, P. J. Garrido, M. I. Bourke, A. Keage, H. A. D. | Brain Commun | 2024 |
Eeg |
| Delirium in Lower Limb Trauma: The Incidence and Risk Factors in a Prospective Observational Study | Balachandran, A. Nagar, M. Behera, P. Kashyap, P. | Indian J Orthop | 2024 |
adults |
| Diurnal variation of postoperative delirium in elderly patients undergoing esketamine anesthesia for elective noncardiac surgery: a randomized clinical trial | Zhang, Y. Chen, R. Tang, S. Sun, T. Yu, Y. Shi, R. Wang, K. Zeng, Z. Liu, X. Meng, Q. Xia, Z. | Int J Surg | 2024 |
Humans |
| Recent developments in delirium after oral and maxillofacial free-flap reconstruction | Zhang, R. Zhang, W. Ren, Y. Yu, J. Li, L. Zhang, Y. | J Stomatol Oral Maxillofac Surg | 2024 |
Oral and maxillofacial free-flap reconstruction |
| A longitudinal multimodal MRI study of the visual network in postoperative delirium | Zhang, G. Qi, B. Li, H. Zhang, X. Chen, J. Li, H. Jing, B. Huang, H. | Brain Imaging Behav | 2024 |
Frontal glioma |
| Association between Intraoperative Hypotension and Postoperative Delirium: A Retrospective Cohort Analysis | Zarour, S. Weiss, Y. Abu-Ghanim, M. Iacubovici, L. Shaylor, R. Rosenberg, O. Matot, I. Cohen, B. | Anesthesiology | 2024 |
Humans |
| Incidence and relative risk of delirium after major surgery for patients with pre-operative depression: a systematic review and meta-analysis | Diep, C. Patel, K. Petricca, J. Daza, J. F. Lee, S. Xue, Y. Kremic, L. Xiao, M. Z. X. Pivetta, B. Vigod, S. N. Wijeysundera, D. N. Ladha, K. S. | Anaesthesia | 2024 |
delirium |
| Pharmacologic Treatment Strategies for Delirium in Hospitalized Adults: Past, Present, and Future | Devlin, J. W. | Semin Neurol | 2024 |
Delirium Cognitive decline Non-pharmacological interventions Risk factors ICU Delirium |
| Reperfusion therapy and risk of post-stroke delirium | Czyzycki, M. Pera, J. Dziedzic, T. | Neurol Res | 2024 |
Delirium |
| Implementation of delirium screening in the emergency department: A qualitative study with early adopters | Chary, A. N. Bhananker, A. R. Brickhouse, E. Torres, B. Santangelo, I. Godwin, K. M. Naik, A. D. Carpenter, C. R. Liu, S. W. Kennedy, M. | J Am Geriatr Soc | 2024 |
delirium |
| Practical prognostic tools to predict the risk of postoperative delirium in older patients undergoing cardiac surgery: visual and dynamic nomograms | Bah, C. S. Mbambara, B. Xie, X. Li, J. Iddi, A. K. Chen, C. Jiang, H. Feng, Y. Zhong, Y. Zhang, X. Xia, H. Yan, L. Si, Y. Zhang, J. Zou, J. | J Clin Monit Comput | 2024 |
Cardiac surgery |
| Validation of the delirium diagnostic tool-provisional (DDT-Pro) in geriatric medical inpatients with diagnostic permutations of the 3Ds with and without delirium | Botero Urrea, M. González, M. C. Villa García, M. M. Alviz Núñez, M. Velásquez-Tirado, J. D. Ocampo, M. V. Trzepacz, P. T. Franco, J. G. | J Psychosom Res | 2024 |
Humans Female |
| Delirium Mediated the Association Between a History of Falls and Short-Term Mortality Risk in Critically Ill Ischemic Stroke Patients | Cheng, H. Xu, X. Tang, Y. Yang, X. Ling, Y. Tan, S. Wang, Z. Ming, W. K. Lyu, J. | Clin Nurs Res | 2024 |
Icu |
| Risk factors for postoperative delirium in frail elderly patients undergoing on-pump cardiac surgery and development of a prediction model-a prospective observational study | Ding, Y. Gao, J. Ge, Y. Huang, T. Zhang, Y. | Front Cardiovasc Med | 2024 |
cardiac surgery |
| Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial | Fathy, W. Hussein, M. Elanwar, R. Elmoutaz, H. Abdelsadek, D. A. Kassim, D. Y. | BMC Anesthesiol | 2024 |
Humans |
| Predicting postoperative delirium assessed by the Nursing Screening Delirium Scale in the recovery room for non-cardiac surgeries without craniotomy: A retrospective study using a machine learning approach | Giesa, N. Haufe, S. Menk, M. Weiß, B. Spies, C. D. Piper, S. K. Balzer, F. Boie, S. D. | PLOS Digit Health | 2024 |
Postoperative Delirium Risk factors Non-linear machine learning Fluctuation Recovery Nurse Screening Delirium Scale |
| A Comparative Analysis of the Effects of Haloperidol and Dexmedetomidine on QTc Interval Prolongation during Delirium Treatment in Intensive Care Units | Haspolat, A. Polat, F. Köprülü, AŞ | J Crit Care Med (Targu Mures) | 2024 |
QTc interval |
| Effect of mannitol on postoperative delirium in patients undergoing coronary artery bypass graft: a randomised controlled trial | Hemmati Maslakpak, M. Negargar, S. Farbod, A. Khalili, A. Bilehjani, E. Alinejad, V. Faravan, A. | Open Heart | 2024 |
Humans |
| Assessing Delirium Severity in Dementia: Item Development and Psychometric Validation for a Delirium Severity Instrument | Hshieh, T. Schulman-Green, D. Fong, T. G. Metzger, E. Arias, F. Helfand, B. Marcantonio, E. Schmitt, E. Tabloski, P. Jones, R. N. Inouye, S. K. | J Gerontol Nurs | 2024 |
Humans |
| The development of a family-led novel intervention for delirium prevention and management in the adult intensive care unit: A co-design qualitative study | Johnson, G. U. Towell-Barnard, A. McLean, C. Ewens, B. | Aust Crit Care | 2024 |
Co-design |
| Disparities in Delirium across the Continuum of Care and Associations with Social Determinants of Health | Khanna, A. Govil, M. Ayele, N. Saadi, A. | Semin Neurol | 2024 |
Delirium identification Delirium treatment Disparities Social-ecological model Social determinants of health |
| The effect of non-steroidal anti-inflammatory drugs on postoperative delirium: a meta-analysis | Kim, S. Y. Na, H. S. Ryu, J. H. Shin, H. J. | Korean J Anesthesiol | 2024 |
Cognitive dysfunction |
| Management of delirium in acute stroke patients: a position paper by the Austrian Stroke Society on prevention, diagnosis, and treatment | Kneihsl, M. Berger, N. Sumerauer, S. Asenbaum-Nan, S. Höger, F. S. Gattringer, T. Enzinger, C. Aigner, M. Ferrari, J. Lang, W. | Ther Adv Neurol Disord | 2024 |
acute stroke |
| Assessment of cognition: dementia and delirium : In consideration of the AWMF guidelines 038-013 and 084-002LG | Krupp, S. Iglseder, B. | Z Gerontol Geriatr | 2024 |
Cognitive impairments |
| Retrospective comparison of the effects of remimazolam and dexmedetomidine on postoperative delirium in elderly patients undergoing orthopedic surgery of the lower extremities under spinal anesthesia | Lee, S. Oh, C. Jung, J. Hong, B. Jo, Y. Lee, S. Lim, C. Baek, S. Shin, M. Seo, H. Chung, W. | J Anesth | 2024 |
Benzodiazepines |
| Cluster nursing care based on 10S continuous quality improvement reduces incidence of postoperative delirium in BPH patients | Li, R. X. Liu, J. Jin, P. Ye, X. Q. Xu, S. | Zhonghua Nan Ke Xue | 2024 |
Humans |
| Elderly patients with dysphagia in the intensive care unit: Association between malnutrition and delirium | Liang, X. Li, X. Cheng, H. Wei, F. Li, T. Li, Y. Huang, Y. Lyu, J. Wang, Y. | Nurs Crit Care | 2024 |
critical care nursing |
| Global Research Trends in Postoperative Delirium and Its Risk Factors: A Bibliometric and Visual Analysis | Liu, X. Huangfu, Z. Zhang, X. Ma, T. | J Perianesth Nurs | 2024 |
bibliometrics |
| Intensive care nurses' perceptions and awareness of delirium and delirium prevention guidelines | Meghani, S. Timmins, F. | Nurs Crit Care | 2024 |
Humans |
| Characteristics associated with effectiveness in postoperative delirium research: a systematic review of randomised controlled trials with meta-regression and meta-analysis | Meng, L. Zhao, X. Sun, Y. Cheng, S. Bao, L. Fang, K. Yu, Q. Zheng, Y. Wang, J. Luo, M. Gunderman, D. Vuckovic, N. Sidhu, A. S. Li, J. Li, G. Wolfe, J. W. Liu, Z. Adams, D. C. | Br J Anaesth | 2024 |
Humans |
| Electroencephalography as a tool for assessing delirium in hospitalized patients: A single-center tertiary hospital experience | Mohamad Faizal, N. S. Tan, J. K. Tan, M. M. Khoo, C. S. Sahibulddin, S. Z. Zolkafli, N. Hod, R. Tan, H. J. | J Cent Nerv Syst Dis | 2024 |
Delirium |
| Common molecular and pathophysiological underpinnings of delirium and Alzheimer's disease: molecular signatures and therapeutic indications | Mosharaf, M. P. Alam, K. Gow, J. Mahumud, R. A. Mollah, M. N. H. | BMC Geriatr | 2024 |
Humans |
| Evaluation of postoperative delirium in geriatric patients given acetaminophen with and without melatonin: A retrospective cohort study | Muehrcke, M. N. Blackwelder, R. S. Weeda, E. R. Furlough, L. A. Shelton, J. E. Brace, S. M. Bragg, S. W. | Int J Psychiatry Med | 2024 |
comorbidity |
| Effect of intranasal insulin on perioperative cognitive function in older adults: a randomized, placebo-controlled, double-blind clinical trial | Sun, M. Ruan, X. Zhou, Z. Huo, Y. Liu, M. Liu, S. Cao, J. Liu, Y. H. Zhang, X. Ma, Y. L. Mi, W. | Age Ageing | 2024 |
Humans |
| Predictive model of risk factors for 28-day mortality in patients with sepsis or sepsis-associated delirium based on the MIMIC-IV database | Zhang, L. Li, X. Huang, J. Yang, Y. Peng, H. Yang, L. Yu, X. | Sci Rep | 2024 |
Humans |
| Exploring Causal Links Between Gut Microbiota and Geriatric Syndromes: A Two-Sample Mendelian Randomization Analysis | Yao, Q. Chen, L. Cai, Y. Li, C. Wen, S. Yang, C. Zhang, Q. Zeng, Y. Zheng, S. Zou, J. Huang, G. Zeng, Q. | Int J Med Sci | 2024 |
Humans |
| Intranasal administration of insulin on the incidence of postoperative delirium in middle-aged patients undergoing elective on-pump cardiac surgery (INIPOD-MOPS): a prospective double-blinded randomized control study protocol | Yang, M. Yang, G. Lu, T. Cao, L. Xiao, C. Liang, Y. Ding, J. Jiang, X. Wang, W. Chen, F. Du, Z. Li, H. | Trials | 2024 |
Humans |
| Integrated Multi-Omics Analysis of Cerebrospinal Fluid in Postoperative Delirium | Tripp, B. A. Dillon, S. T. Yuan, M. Asara, J. M. Vasunilashorn, S. M. Fong, T. G. Inouye, S. K. Ngo, L. H. Marcantonio, E. R. Xie, Z. Libermann, T. A. Otu, H. H. | Biomolecules | 2024 |
Humans |
| Sex-stratified analyses of comorbidities associated with an inpatient delirium diagnosis using real world data | Sirota, M. Kodama, L. Woldemariam, S. Tang, A. Li, Y. Kornak, J. Allen, I. E. Raphael, E. Oskotsky, T. | Res Sq | 2024 |
Delirium Older Adults Comorbidities Mental Health Inpatient delirium |
| Reasons influencing the nurses' prioritization process while preventing and managing delirium: findings from a qualitative study | Sist, L. Ugenti, N. V. Chiappinotto, S. Messina, R. Rucci, P. Palese, A. | Aging Clin Exp Res | 2024 |
Humans |
| Clinical and Cognitive Characteristics Associated with the Onset of Delirium in Postoperative Cardiovascular Surgery Patients Admitted to the ICU | Sano, K. Watanabe, A. Kawaguchi, T. Sakamoto, Y. Fukuda, M. | Prog Rehabil Med | 2024 |
Icu |
| Incidence and related risk factors for postoperative delirium following revision total knee arthroplasty: a retrospective nationwide inpatient sample database study | Peng, Z. Wu, J. Wang, Z. Xie, H. Wang, J. Zhang, P. Yang, Q. Luo, Y. | BMC Musculoskelet Disord | 2024 |
Humans |
| Value of the Safety Management System (VMS) frailty instrument as a frailty screener in care for older hospital patients: a systematic review | Oud, F. M. M. Meulman, M. D. Merten, H. Wagner, C. van Munster, B. C. | Eur Geriatr Med | 2024 |
Humans |
| Prediction of Post-Operative Delirium in Older Adults from Preoperative Cognition and Alpha Power from Resting-State EEG | Ning, M. Rodionov, A. Ross, J. M. Ozdemir, R. A. Burch, M. Lian, S. J. Alsop, D. Cavallari, M. Dickerson, B. C. Fong, T. G. Jones, R. N. Libermann, T. A. Marcantonio, E. R. Santarnecchi, E. Schmitt, E. M. Touroutoglou, A. Travison, T. G. Acker, L. Reese, | medRxiv | 2024 |
Postoperative Delirium MoCA Preoperative cognitive function EEG |
| Gabapentinoids-Related Delirium Adverse Events: A Real-World Study from 2004 to 2022 Based on FAERS | Nie, Z. Liang, C. Li, Z. Han, X. Zhang, R. | J Pain Res | 2024 |
Faers |
| TEGEST as promising tool for assessing the risk of perioperative neurocognitive disorders | Nekvindová, K. Ivanová, K. Juríčková, L. Gabrhelík, T. | BMC Geriatr | 2024 |
Humans |
| Incidence and Risk Factors of Developing Post-operative Delirium Among Elderly Patients in a Tertiary Care Hospital: A Retrospective Chart Review | Almashari, Y. Alshaya, R. A. Alenazi, R. R. Alanazi, A. M. Alhanan, R. Al-Shammari, F. A. Muawad, R. | Cureus | 2024 |
anesthesia |
| Predictive factors for the duration of subsyndromal delirium in the intensive care unit | Song, C. Wang, S. Liu, J. Xu, W. Yang, Y. Li, X. | J Clin Nurs | 2024 |
Humans |
| Cognitive and functional change in skilled nursing facilities: Differences by delirium and Alzheimer's disease and related dementias | Saczynski, J. S. Koethe, B. Fick, D. M. Vo, Q. T. Devlin, J. W. Marcantonio, E. R. Briesacher, B. A. | J Am Geriatr Soc | 2024 |
Alzheimer’s disease and related dementias |
| Effects of a Standardized Patient-Based Delirium Care Education Program | Roh, Y. S. Jung, M. J. Issenberg, S. B. | Res Theory Nurs Pract | 2024 |
Humans |
| Hemoglobin level, degree of mobilization, and pneumonia are associated with the development of postoperative delirium in cemented hemiarthroplasty after femoral neck fracture | Riemenschneider, J. Dobrawa, P. Sturm, R. Meier, S. L. Verboket, R. Marzi, I. Störmann, P. | Eur J Trauma Emerg Surg | 2024 |
Complications |
| Assessing Delirium in Patients With Neurological Diseases | Nisgaard, M. G. Boesen, S. V. Jensen, J. | J Neurosci Nurs | 2024 |
Delirium Intensive Care Delirium Screening Checklist Confusion Assessment Method Screening tools Hospital complications
|
| The Approach to Altered Mental Status in the Intensive Care Unit | Albin, C. S. W. Cunha, C. B. Glaser, T. P. Schachter, M. Snow, J. W. Oto, B. | The Approach to Altered Mental Status in the Intensive Care Unit | 2024 |
Altered mental status Intensive care unit Bedside assessment Delirium Review |
| Impact of inhaled sedation on delirium incidence and neurological outcome after cardiac arrest - A propensity-matched control study (Isocare) | Teiten, C. Bailly, P. Tonnelier, J. M. Bodenes, L. de Longeaux, K. L'Her, E. | Resuscitation | 2024 |
Cardiac arrest |
| Delirium care burden of intensive care nurses caring for patients undergoing open-heart surgery: A mixed-method research | Ulus, M. Durmaz Edeer, A. | Nurs Crit Care | 2024 |
caregiver burden |
| Delirium prevalence in emergency department patients: A systematic review and meta-analysis | Wang, Y. Dai, M. Chen, X. Zhang, J. | Nurs Crit Care | 2024 |
acute confusional state |
| Postoperative delirium increases follow-up mortality following hip arthroplasty in older patients with femoral neck fracture | Wu, P. Yang, Y. Yuan, A. Wang, Y. Zhang, Y. | Australas J Ageing | 2024 |
delirium |
| Analysis of risk factors for postoperative delirium in elderly patients undergoing spinal surgery | Zhang, W. P. Chang, W. X. Liu, W. Y. Li, Z. J. Mao, J. W. | Zhongguo Gu Shang | 2024 |
Humans |
| Effect of occupational therapy on the occurrence of delirium in critically ill patients: a systematic review and meta-analysis | Zhao, J. Fan, K. Zheng, S. Xie, G. Niu, X. Pang, J. Zhang, H. Wu, X. Qu, J. | Front Neurol | 2024 |
critically ill patients |
| Serum HMGB1 as a predictor for postoperative delirium in elderly patients undergoing total hip arthroplasty surgery | Zou, Y. Wu, Y. Wei, A. Nie, H. Hui, S. Liu, C. Deng, T. | Adv Clin Exp Med | 2024 |
Hmgb1 |
| The impact of adhering to a quality indicator for sedation, analgesia, and delirium management on costs, revenues, and clinical outcomes in intensive care in Germany: A retrospective observational study | Zuber, A. Rubarth, K. Förster, F. Balzer, F. Spies, C. Fürstenau, D. Kumpf, O. | PLoS One | 2024 |
Humans |
| The association between intraoperative hypotension and postoperative delirium- a retrospective cohort analysis | Zarour, S. Weiss, Y. Abu-Ganim, M. Iacubovici, L. Shaylor, R. Rosenberg, O. Matot, I. Cohen, B. | Anesthesiology | 2024 |
Hypotension Postoperative delirium Elective surgery Elderly Intraoperative Hypotension 4A’s |
| Intensive Care Unit Sleep Promotion Bundle: Impact on Sleep Quality, Delirium, and Other Patient Outcomes | Gorecki, N. M. Prasun, M. A. | Crit Care Nurse | 2024 |
Humans |
| A prospective multi-center study quantifying visual inattention in delirium using generative models of the visual processing stream | Al-Hindawi, A. Vizcaychipi, M. Demiris, Y. | Sci Rep | 2024 |
Humans |
| Correlation of preoperative inflammatory factors and emotional disorders with postoperative delirium in patients with craniocerebral trauma | Cao, P. Jia, Z. Y. Zheng, T. Mei, T. | World J Psychiatry | 2024 |
Inflammatory factors |