What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Extracellular Vesicle MicroRNAs as Predictive Biomarkers in Postoperative Delirium After Spine Surgery: Preliminary Study
- Authors
- Cho, Y. E. Kim, J. Vorn, R. Cho, H. Baek, W. Park, H. Yun, S. Kim, H. S. Cashion, A. K. Gill, J. Koo, B. N. Lee, H.
- Year
- 2024
- Journal
- J Gerontol A Biol Sci Med Sci
- Abstract
Postoperative delirium (POD) can cause poor patient outcomes in older adults who undergo surgery. In this study, we tested plasma extracellular vesicle (EV) miRNAs obtained before the delirium event to find predictive POD biomarkers after spine surgery. We recruited patients who are more than 70 years old and have undergone spine surgery. Finally, POD patients (n = 31) were included, with no-POD patients matched in age, sex, medical history, and type of surgery (n = 31). Peripheral blood was collected from patients in the operating room after the operation was completed. EVs were isolated from plasma, and the 798 miRNA expression level from EVs was measured using a NanoString platform. Sixty-two patients were included in the study; all were Korean, 67.7% were females, and the median age was 75 years. Preoperative medical history was not statistically different between no-POD and POD patients except for hypertension and the American Society of Anesthesiologists physical status. From the miRNA profiling, we identified 142 significantly differentially expressed miRNAs in POD patients compared with no-POD patients, which are associated with psychological/neurological disorders. The top 10 differentially expressed miRNAs including miR-548ar-5p and miR-627-5p were all upregulated in POD patients and the results were validated using qRT-PCR from the independent sets of samples (n = 96). We demonstrated the potential of plasma EV-miRNAs as predictive biomarkers to identify the risk group of POD after spine surgery. It also provides opportunities for future studies investigating the role of EV-miRNAs in delirium pathology.
- PMID
PMID: 38970345
PMCID: PMC11398910
- Keywords
Humans
Female
Male
Aged
*Extracellular Vesicles/metabolism
*MicroRNAs/blood
*Biomarkers/blood
*Delirium/blood/etiology
*Postoperative Complications/blood
Spine/surgery
Aged, 80 and over
Exosome
Genomics
Prediction
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Prophylactic use of ramelteon for delirium in hospitalized patients: A systematic review and meta-analyses | Dang, V. Mansukhani, M. P. Wang, Z. Vesely, E. K. Kolla, B. P. | J Acad Consult Liaison Psychiatry | 2022 |
Delirium |
| Longest and largest cohort study of delirium to date reinforces association while causation remains elusive | Cunningham, E. | J Neurol Neurosurg Psychiatry | 2022 |
Cognition |
| Documentation and Diagnosis of Delirium in Parkinson's Disease | Cullinan, R. J. Richardson, S. J. Yarnall, A. J. Burn, D. J. Allan, L. M. Lawson, R. A. | Acta Psychiatr Scand | 2022 |
Confusion |
| Avoiding pitfalls in the treatment of delirium | Chuang, Y. C. Lin, C. Y. Wang, J. K. | Aust N Z J Psychiatry | 2022 |
*Delirium/drug therapy |
| Less pharmacotherapy is more in delirium | Chou, S. T. Pogach, M. Rock, L. K. | Intensive Care Med | 2022 |
*Antipsychotic Agents/therapeutic use |
| Accuracies of Training Labels and Machine Learning Models: Experiments on Delirium and Simulated Data | Cheng, Y. Shao, Y. Rudolph, J. Weir, C. R. Sahlmann, B. Zeng-Treitler, Q. | Stud Health Technol Inform | 2022 |
*Delirium |
| E4BP4 Coordinates Circadian Control of Cognition in Delirium | Chen, M. Zhang, L. Shao, M. Du, J. Xiao, Y. Zhang, F. Zhang, T. Li, Y. Zhou, Q. Liu, K. Wang, Z. Wu, B. | Adv Sci (Weinh) | 2022 |
E4bp4 |
| Association Between Anesthetics and Postoperative Delirium in Elderly Patients Undergoing Spine Surgery: Propofol Versus Sevoflurane | Chang, J. E. Min, S. W. Kim, H. Won, D. Lee, J. M. Kim, T. K. Kim, C. Hwang, J. Y. | Global Spine J | 2022 |
anesthesia |
| Validation of a delirium predictive model in patients admitted to surgical intensive care units: a multicentre prospective observational cohort study | Chaiwat, O. Chittawatanarat, K. Mueankwan, S. Morakul, S. Dilokpattanamongkol, P. Thanakiattiwibun, C. Siriussawakul, A. | BMJ Open | 2022 |
Adult |
| Lidocaine Infusion for the Management of Postoperative Pain and Delirium (LIMPP): protocol for a randomised control trial | Buren, M. A. Theologis, A. Zuraek, A. Behrends, M. Clark, A. J. Leung, J. M. | BMJ Open | 2022 |
Aged |
| Factors influencing resilience to postoperative delirium in adults undergoing elective orthopaedic surgery | Bowman, E. M. L. Cardwell, C. McAuley, D. F. McGuinness, B. Passmore, A. P. Beverland, D. Zetterberg, H. Schott, J. M. Cunningham, E. L. | Br J Surg | 2022 | |
| Delirium prediction in the ICU: designing a screening tool for preventive interventions | Bhattacharyya, A. Sheikhalishahi, S. Torbic, H. Yeung, W. Wang, T. Birst, J. Duggal, A. Celi, L. A. Osmani, V. | JAMIA Open | 2022 |
artificial intelligence |
| Regional vs General Anesthesia and Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery | Zhu, Z. Cao, P. Lin, L. | Jama | 2022 |
Aged |
| Melatonin intervention to prevent delirium in hospitalized patients: A meta-analysis | You, W. Fan, X. Y. Lei, C. Nie, C. C. Chen, Y. Wang, X. L. | World J Clin Cases | 2022 |
Delirium |
| Preoperative Low Physical Activity is a Predictor of Postoperative Delirium in Patients with Gastrointestinal Cancer: A Retrospective Study | Yanagisawa, T. Tatematsu, N. Horiuchi, M. Migitaka, S. Yasuda, S. Itatsu, K. Kubota, T. Sugiura, H. | Asian Pac J Cancer Prev | 2022 |
Activities of Daily Living |
| What is It Like to be Delirious? | Wijdicks, E. F. M. Rabinstein, A. A. | Neurocrit Care | 2022 |
Definitions |
| Impact of Pain, Agitation, and Delirium Bundle on Delirium and Cognitive Function | Wang, X. P. Lv, D. Chen, Y. F. Chen, N. Li, X. D. Xu, C. F. Li, Y. Tian, L. | J Nurs Res | 2022 | |
| Regional vs General Anesthesia and Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery | Uzoigwe, C. E. Campbell-Jones, F. | Jama | 2022 |
Aged |
| Improving delirium screening in older adults at the Royal United Hospital, Bath | Trew, C. A. Cross, R. Howell, K. Dyer, C. | Br J Hosp Med (Lond) | 2022 |
Aged |
| Assessing prevalence and independent predictors of postoperative delirium in patients with head and neck cancer | Tian, T. Xue, F. S. Shao, L. J. Z. Hu, B. | Br J Oral Maxillofac Surg | 2022 |
*Delirium/epidemiology/etiology |
| Delirium due to hip fracture is associated with activated immune-inflammatory pathways and a reduction in negative immunoregulatory mechanisms | Thisayakorn, P. Thipakorn, Y. Tantavisut, S. Sirivichayakul, S. Maes, M. | BMC Psychiatry | 2022 |
Aged |
| Retrospective evaluation of a delirium order set utilizing nonpharmacologic and pharmacologic interventions for the treatment of delirium in medical intensive care unit patients | Taylor, A. D. Chen, A. Reddy, A. J. Lewandowski, A. Torbic, H. | Am J Health Syst Pharm | 2022 |
Adolescent |
| Prevention of dexmedetomidine on postoperative delirium and early postoperative cognitive dysfunction in elderly patients undergoing hepatic lobectomy | Tang, Y. Wang, Y. Kong, G. Zhao, Y. Wei, L. Liu, J. | Zhong Nan Da Xue Xue Bao Yi Xue Ban | 2022 |
Aged |
| Prevalence, clinical features, and risk factors of delusions in patients with delirium | Tachibana, M. Inada, T. Ichida, M. Ozaki, N. | Int J Geriatr Psychiatry | 2022 | |
| Effect of sedative premedication with oral midazolam on postanesthesia care unit delirium in older adults: a secondary analysis following an uncontrolled before-after design | Stuff, K. Kainz, E. Kahl, U. Pinnschmidt, H. Beck, S. von Breunig, F. Nitzschke, R. Funcke, S. Zöllner, C. Fischer, M. | Perioper Med (Lond) | 2022 |
Anesthesia |
| Associations of Smoking With Delirium and Opioid Use in Older Adults With Traumatic Hip Fracture | Salottolo, K. Meinig, R. Fine, L. Kelly, M. Madayag, R. Ekengren, F. Tanner, A., 2nd Bar-Or, D. | J Am Acad Orthop Surg Glob Res Rev | 2022 |
Aged |
| Impact of delirium on mortality in patients hospitalized for heart failure | Ritchie, C. Walters, R. W. Ramaswamy, S. Alla, V. M. | Int J Psychiatry Med | 2022 |
Aged |
| Risk for post-operative delirium related to comorbidities in older adult cardiac patients: An integrative review | Ramos, M. D. Vergara, F. H. Shackleford, J. Briggs, C. Gomez, C. Mofazali, M. Preston, J. | J Clin Nurs | 2022 |
cardiac surgery |
| Diagnosis and management of delirium in hospital oncology services | Ramírez Zuluaga, L. P. Ruano Restrepo, M. I. Osorio Bermúdez, J. D. Díaz Vallejo, J. A. | J Geriatr Oncol | 2022 |
*Delirium/diagnosis/etiology/therapy |
| Cognitive Predictors of Delirium on Long-Term Follow-Up after TIA and Stroke: Population-Based Cohort Study | Pendlebury, S. T. Thomson, R. J. Welch, S. J. V. Rothwell, P. M. | Cerebrovasc Dis | 2022 |
Aged |
| Plasma neurofilament light chain protein as a predictor of days in delirium and deep sedation, mortality and length of stay in critically ill patients | Page, V. J. Watne, L. O. Heslegrave, A. Clark, A. McAuley, D. F. Sanders, R. D. Zetterberg, H. | EBioMedicine | 2022 |
Biomarker |
| Feasibility of Machine Learning and Logistic Regression Algorithms to Predict Outcome in Orthopaedic Trauma Surgery | Oosterhoff, J. H. F. Gravesteijn, B. Y. Karhade, A. V. Jaarsma, R. L. Kerkhoffs, Gmmj Ring, D. Schwab, J. H. Steyerberg, E. W. Doornberg, J. N. | J Bone Joint Surg Am | 2022 |
Algorithms |
| Delirium detection methodologies: Implications for outcome measurement in clinical trials in postoperative delirium | Oh, E. S. Rosenberg, P. B. Wang, N. Y. Sieber, F. E. Neufeld, K. J. | Int J Geriatr Psychiatry | 2022 |
Aged |
| Nurse staffing levels are not associated with appearance, duration or solution of delirium in stroke patients | Nydahl, P. Meyne, J. Osterbrink, J. Margraf, N. G. | Intensive Crit Care Nurs | 2022 |
*Delirium/complications |
| Regional vs General Anesthesia and Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery | Nobuhara, C. Devinney, M., Jr. Berger, M. | Jama | 2022 |
Aged |
| Linking Perioperative Medications and Delirium | Nathan, N. | Anesth Analg | 2022 |
*Delirium/chemically induced/diagnosis |
| Prolonged and severe post-electroconvulsive therapy delirium with concurrent clozapine therapy | Melnikoff, E. Thomas Johnson, E. Walker, F. Itrat, Q. Jagadheesan, K. | Aust N Z J Psychiatry | 2022 |
*Antipsychotic Agents/adverse effects |
| 'Excited Delirium', acute behavioural disturbance, death and diagnosis | McGuinness, T. Lipsedge, M. | Psychol Med | 2022 |
Acute behavioural disturbance |
| Effects of non-pharmacologic prevention on delirium in critically ill patients: A network meta-analysis | Matsuura, Y. Ohno, Y. Toyoshima, M. Ueno, T. | Nurs Crit Care | 2022 |
acute encephalopathy |
| Melatonin Receptor Agonists for the Prevention of Delirium: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials | Maneeton, B. Kongsaengdao, S. Maneeton, N. Likhitsathian, S. Woottiluk, P. Kawilapat, S. Srisurapanont, M. | Curr Neuropharmacol | 2022 |
Delirium |
| Potential Value of Serum Lipid in the Identication of Postoperative Delirium Undergoing Knee/Hip Arthroplasty: The Perioperative Neurocognitive Disorder and Biomarker Lifestyle Study | Lin, Y. Peng, X. Lin, X. Deng, X. Liu, F. Tao, H. Dong, R. Wang, B. Bi, Y. | Front Psychiatry | 2022 |
cholesterol |
| Habitual tea consumption and postoperative delirium after total hip/knee arthroplasty in elderly patients: The PNDABLE study | Lin, X. Li, X. X. Dong, R. Wang, B. Bi, Y. L. | Brain Behav | 2022 |
cholinergic nerve system |
| Delirium and the risk of developing dementia: a cohort study of 12 949 patients | Leighton, S. P. Herron, J. W. Jackson, E. Sheridan, M. Deligianni, F. Cavanagh, J. | J Neurol Neurosurg Psychiatry | 2022 |
Dementia |
| Delirium risk factors analysis post proximal femur fracture surgery in elderly | Leigheb, M. De Sire, A. Zeppegno, P. Forni, F. Sgreccia, M. Gagliardi, V. P. Pogliacomi, F. Sabbatini, M. | Acta Biomed | 2022 |
Aged |
| A Scoping Review of the Incidence, Predictors, and Outcomes of Delirium Among Critically Ill Stroke Patients | Lawson, T. N. Balas, M. C. McNett, M. | J Neurosci Nurs | 2022 |
Adult |
| Non-Pharmacological Nursing Interventions to Prevent Delirium in ICU Patients-An Umbrella Review with Implications for Evidence-Based Practice | Lange, S. Mędrzycka-Dąbrowska, W. Friganovic, A. Oomen, B. Krupa, S. | J Pers Med | 2022 |
Icu |
| A decision tree prediction model for a short-term outcome of delirium in patients with advanced cancer receiving pharmacological interventions: A secondary analysis of a multicenter and prospective observational study (Phase-R) | Kurisu, K. Inada, S. Maeda, I. Ogawa, A. Iwase, S. Akechi, T. Morita, T. Oyamada, S. Yamaguchi, T. Imai, K. Nakahara, R. Kaneishi, K. Nakajima, N. Sumitani, M. Yoshiuchi, K. | Palliat Support Care | 2022 |
Decision Trees |
| Postoperative delirium is an independent factor influencing the length of stay of elderly patients in the intensive care unit and in hospital | Kirfel, A. Guttenthaler, V. Mayr, A. Coburn, M. Menzenbach, J. Wittmann, M. | J Anesth | 2022 |
Aged |
| Cost-effectiveness of clinical interventions for delirium: A systematic literature review of economic evaluations | Kinchin, I. Edwards, L. Hosie, A. Agar, M. Mitchell, E. Trepel, D. | Acta Psychiatr Scand | 2022 |
cost-effectiveness |
| Effects of non-pharmacological interventions for preventing delirium in general ward inpatients: A systematic review & meta-analysis of randomized controlled trials | Kim, Y. H. Kim, N. Y. Ryu, S. | PLoS One | 2022 |
Adult |
| Analysis of the Incidence and Risk Factors of Postoperative Delirium in Patients With Degenerative Cervical Myelopathy | Kim, N. Kim, T. H. Oh, J. K. Lim, J. Lee, K. U. Kim, S. W. | Neurospine | 2022 |
Cervical myelopathy |
| Intraoperative low tidal volume ventilation and the risk of ICD-10 coded delirium and the use for antipsychotic medications | Karalapillai, D. Weinberg, L. Neto, A. S. Peyton, P. J. Ellard, L. Hu, R. Pearce, B. Tan, C. Story, D. O'Donnell, M. Hamilton, P. Oughton, C. Galtieri, J. Appu, S. Wilson, A. Eastwood, G. Bellomo, R. Jones, D. A. | BMC Anesthesiol | 2022 |
Adult |
| Falling for It: Of Falls, Families, and Delirium | Jiménez, J. V. Hyzy, R. C. | Crit Care Med | 2022 |
*Accidental Falls |
| Safety and Effectiveness of Perospirone in Comparison to Risperidone for Treatment of Delirium in Patients with Advanced Cancer: A Multicenter Prospective Observational Study in Real-World Psycho-Oncology Settings | Inoue, S. Maeda, I. Ogawa, A. Yoshiuchi, K. Terada, S. Yamada, N. | Acta Med Okayama | 2022 |
Aged |
| Higher Grade Glioma Increases the Risk of Postoperative Delirium: Deficient Brain Compensation Might Be a Potential Mechanism of Postoperative Delirium | Huang, H. W. Zhang, X. K. Li, H. Y. Wang, Y. G. Jing, B. Chen, Y. Patel, M. B. Ely, E. W. Liu, Y. O. Zhou, J. X. Lin, S. Zhang, G. B. | Front Aging Neurosci | 2022 |
brain cognitive compensation |
| Fluconazole-induced delirium in an older patient with schizophrenia | Hu, T. M. Wu, C. L. | Psychogeriatrics | 2022 | |
| Knowledge assessment is key to identifying the training needs of delirium care | Ho, M. H. | Intensive Crit Care Nurs | 2022 |
*Delirium/nursing/therapy |
| Anticholinergic Drug Exposure Increases the Risk of Delirium in Older Patients Undergoing Elective Surgery | Herrmann, M. L. Boden, C. Maurer, C. Kentischer, F. Mennig, E. Wagner, S. Conzelmann, L. O. Förstner, B. R. Rapp, M. A. von Arnim, C. A. F. Denkinger, M. Eschweiler, G. W. Thomas, C. | Front Med (Lausanne) | 2022 |
acute encephalopathy |
| A prediction model for delirium after cardiac surgery: Another step towards prevention? | Herman, J. A. Urman, R. D. Urits, I. Kaye, A. D. Viswanath, O. | J Clin Anesth | 2022 |
*Cardiac Surgical Procedures/adverse effects |
| The effect of a dexmedetomidine infusion on delirium in the ICU | Herman, J. A. Urman, R. D. Urits, I. Kaye, A. D. Viswanath, O. | J Clin Anesth | 2022 |
*Delirium/chemically induced/drug therapy |
| Which interventions can reduce post-operative delirium in the elderly? Synthesis of multidisciplinary and pharmacological intervention data | Herman, J. Urman, R. D. Urits, I. Kaye, A. D. Viswanath, O. | J Clin Anesth | 2022 |
Aged |
| What is the impact of perioperative cerebral oxygen desaturation on postoperative delirium in old population: a systemic review and meta-analysis | He, K. Q. Wang, S. Zhang, W. Liu, Q. Chai, X. Q. | Aging Clin Exp Res | 2022 |
Cerebral oxygen saturation |
| Midazolam and delirium: can you have it both ways? | Greengrass, R. A. | Reg Anesth Pain Med | 2022 |
*Delirium/chemically induced/diagnosis |
| Music Interventions and Delirium in Adults: A Systematic Literature Review and Meta-Analysis | Golubovic, J. Neerland, B. E. Aune, D. Baker, F. A. | Brain Sci | 2022 |
acute confusion |
| In older adults having hip fracture surgery, regional vs. general anesthesia did not reduce postoperative delirium | Gill, S. S. | Ann Intern Med | 2022 |
Aged |
| Relationship between preoperative anxiety and onset of delirium after cardiovascular surgery in elderly patients: focus on personality and coping process | Fukunaga, H. Sugawara, H. Koyama, A. Okamoto, K. Fukui, T. Ishikawa, T. Takebayashi, M. Sekiyama, K. Hashimoto, M. | Psychogeriatrics | 2022 |
agreeableness |
| Identifying Delirium in Persons With Moderate or Severe Dementia: Review of Challenges and an Illustrative Approach | Fong, T. G. Hshieh, T. T. Tabloski, P. A. Metzger, E. D. Arias, F. Heintz, H. L. Patrick, R. E. Lapid, M. I. Schmitt, E. M. Harper, D. G. Forester, B. P. Inouye, S. K. | Am J Geriatr Psychiatry | 2022 |
Advanced dementia |
| Depression is associated with delirium after cardiac surgery - A population-based cohort study | Falk, A. Kåhlin, J. Nymark, C. Hultgren, R. Stenman, M. | Interact Cardiovasc Thorac Surg | 2022 |
Cardiac surgery |
| Incidence, characteristics and risk factors of delirium in the intensive care unit: An observational study | Erbay Dalli, Ö Kelebek Girgin, N. Kahveci, F. | J Clin Nurs | 2022 |
critically ill |
| Incidence, characteristics and risk factors of delirium in the intensive care unit: An observational study | Erbay Dalli, Ö Kelebek Girgin, N. Kahveci, F. | J Clin Nurs | 2022 |
critically ill |
| Association Between Perioperative Medication Use and Postoperative Delirium and Cognition in Older Adults Undergoing Elective Noncardiac Surgery | Duprey, M. S. Devlin, J. W. Griffith, J. L. Travison, T. G. Briesacher, B. A. Jones, R. Saczynski, J. S. Schmitt, E. M. Gou, Y. Marcantonio, E. R. Inouye, S. K. | Anesth Analg | 2022 |
Aged |
| Comparison of incidence of emergence delirium in pediatric patients with three different techniques of general anesthesia using sevoflurane and propofol: a randomized controlled trial | Deepak, M. Shilpa, G. Nikhil, K. Ankur, S. Rakesh, K. Swati, C. Akhil, G. Pradeep, B. | Braz J Anesthesiol | 2022 | |
| Delirium and long-term psychopathology following surgery in older adults | de Mul, N. van den Bos, Lmec Kant, I. M. J. van Montfort, S. J. T. Schellekens, W. M. Cremer, O. L. Slooter, A. J. C. | J Psychosom Res | 2022 |
Aged |
| Study protocol to test the efficacy of self-administration of dexmedetomidine sedative therapy on anxiety, delirium, and ventilator days in critically ill mechanically ventilated patients: an open-label randomized clinical trial | Chlan, L. L. Weinert, C. R. Tracy, M. F. Skaar, D. J. Gajic, O. Ask, J. Mandrekar, J. | Trials | 2022 |
Aftercare |
| Corticosteroids in patients undergoing cardiac surgery: A meta-analysis of 12,559 patients | Chen, L. Xiang, F. Hu, Y. | Perfusion | 2022 |
cardiac surgery |
| Postoperative outcomes in older surgical patients with preoperative cognitive impairment: A systematic review and meta-analysis | Chen, L. Au, E. Saripella, A. Kapoor, P. Yan, E. Wong, J. Tang-Wai, D. F. Gold, D. Riazi, S. Suen, C. He, D. Englesakis, M. Nagappa, M. Chung, F. | J Clin Anesth | 2022 |
Cognitive impairment |
| Benzodiazepine-Based Sedation Did Not Add an Independent Risk of Delirium? | Cai, X. Gao, R. Zhang, S. Chen, C. | Crit Care Med | 2022 |
*Benzodiazepines/adverse effects |
| Natural language processing and detecting delirium | Burki, T. | Lancet Respir Med | 2022 | |
| Delirium risk factors in hospitalized patient: a comprehensive evaluation of underlying diseases and medications in different wards of a large Urban Hospital Center in Iran | Arbabi, M. Ziaei, E. Amini, B. Ghadimi, H. Rashidi, F. Shohanizad, N. Moradi, S. Beikmarzehei, A. Hasanzadeh, A. Parsaei, A. | BMC Anesthesiol | 2022 |
*Delirium/epidemiology |
| Depression and anxiety increase the odds of developing delirium in ICU patients; a prospective observational study | Arbabi, M. Dezhdar, Z. Amini, B. Dehnavi, A. Z. Ghasemi, M. | Cogn Neuropsychiatry | 2022 |
Anxiety |
| Andersen-Ranberg, N. Poulsen, L. M. Perner, A. Hästbacka, J. Morgan, M. P. G. Citerio, G. Oxenbøll-Collet, M. Weber, S. O. Andreasen, A. S. Bestle, M. H. Uslu, B. Pedersen, H. B. S. Nielsen, L. G. Damgaard, K. Jensen, T. B. Sommer, T. Dey, N. Mathiesen, | Agents intervening against delirium in the intensive care unit trial-Protocol for a secondary Bayesian analysis | Acta Anaesthesiol Scand | 2022 |
Bayesian statistics |
| Sleep monitoring challenges in patients with neurocognitive disorders: A cross-sectional analysis of missing data from activity trackers | Ahuja, M. Siddhpuria, S. Reppas-Rindlisbacher, C. Wong, E. Gormley, J. Lee, J. Patterson, C. | Health Sci Rep | 2022 |
activity monitor |
| The Dilemma of Treating Delirium: the Conundrum of Drug Management | Agar, M. R. Amgarth-Duff, I. | Curr Treat Options Oncol | 2022 |
Antipsychotics |
| Gabapentinoid Use Is Associated With Reduced Occurrence of Hyperactive Delirium in Older Cancer Patients Undergoing Chemotherapy: A Nationwide Retrospective Cohort Study in Japan | Abe, H. Sumitani, M. Matsui, H. Inoue, R. Konishi, M. Fushimi, K. Uchida, K. Yasunaga, H. | Anesth Analg | 2022 |
Gabapentinoid Use Is Associated With Reduced Occurrence of Hyperactive Delirium in Older Cancer Patients Undergoing Chemotherapy: A Nationwide Retrospective Cohort Study in Japan |
| Incidence, predictors and health outcomes of delirium in very old hospitalized patients: a prospective cohort study | Zhang, M. Zhang, X. Gao, L. Yue, J. Jiang, X. | BMC Geriatr | 2022 |
Aged |
| The effect of delirium information training given to intensive care nurses on patient care: quasi-experimental study | Yıldırım, F. Türkleş, S. Altundal Duru, H. | PeerJ | 2022 |
Checklist |
| Mechanical Bowel Preparation Is a Risk Factor for Postoperative Delirium as It Alters the Gut Microbiota Composition: A Prospective Randomized Single-Center Study | Yang, Z. Tong, C. Qian, X. Wang, H. Wang, Y. | Front Aging Neurosci | 2022 |
gastrectomy |
| The Mini-Cog: A simple screening tool for cognitive impairment useful in predicting the risk of delirium after major urological cancer surgery | Yajima, S. Nakanishi, Y. Matsumoto, S. Ookubo, N. Tanabe, K. Kataoka, M. Masuda, H. | Geriatr Gerontol Int | 2022 |
Activities of Daily Living |
| A Novel Radiomics-Based Machine Learning Framework for Prediction of Acute Kidney Injury-Related Delirium in Patients Who Underwent Cardiovascular Surgery | Xue, X. Chen, W. Chen, X. | Comput Math Methods Med | 2022 |
*Acute Kidney Injury/diagnostic imaging/etiology |
| The Effect of Preoperative Methylprednisolone on Postoperative Delirium in Older Patients Undergoing Gastrointestinal Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial | Xiang, X. B. Chen, H. Wu, Y. L. Wang, K. Yue, X. Cheng, X. Q. | J Gerontol A Biol Sci Med Sci | 2022 |
Aged |
| Head-to-head comparison of 14 prediction models for postoperative delirium in elderly non-ICU patients: an external validation study | Wong, C. K. van Munster, B. C. Hatseras, A. Huis In 't Veld, E. van Leeuwen, B. L. de Rooij, S. E. Pleijhuis, R. G. | BMJ Open | 2022 |
Aged |
| Impact of a dementia-friendly program on detection and management of patients with cognitive impairment and delirium in acute-care hospital units: a controlled clinical trial design | Weldingh, N. M. Mellingsæter, M. R. Hegna, B. W. Benth, J. S. Einvik, G. Juliebø, V. Thommessen, B. Kirkevold, M. | BMC Geriatr | 2022 |
Aged |
| Influence of Patient-Specific Covariates on Test Validity of Two Delirium Screening Instruments in Neurocritical Care Patients (DEMON-ICU) | Weiss, B. Paul, N. Spies, C. D. Ullrich, D. Ansorge, I. Salih, F. Wolf, S. Luetz, A. | Neurocrit Care | 2022 |
Critical Care/methods |
| Development and Validation of a Postoperative Delirium Prediction Model for Elderly Orthopedic Patients in the Intensive Care Unit | Wang, G. Zhang, L. Qi, Y. Chen, G. Zhou, J. Zhu, H. Hao, Y. | J Healthc Eng | 2022 |
Aged |
| Effects of Atorvastatin Therapy on Postoperative Delirium After Malignant Tumor Surgeries in Older Adults | Wan, R. Cai, S. Pan, D. Yang, W. Zhou, R. | Neuropsychiatr Dis Treat | 2022 |
30-day all-cause mortality |
| Psychometric Properties of a Delirium Severity Score for Older Adults and Association With Hospital and Posthospital Outcomes | Vasunilashorn, S. M. Fong, T. G. Helfand, B. K. I. Hshieh, T. T. Marcantonio, E. R. Metzger, E. D. Schmitt, E. M. Tabloski, P. A. Travison, T. G. Gou, Y. Jones, R. N. Inouye, S. K. | JAMA Netw Open | 2022 |
Aged |
| Delirium can be safely managed in the community through implementation of a community toolkit: a proof-of-concept pilot study | Vardy, E. Roberts, S. Pratt, H. | Future Healthc J | 2022 |
assessment |
| Delirium as a Presenting Symptom of COVID-19 | Tyson, B. Shahein, A. Erdodi, L. Tyson, L. Tyson, R. Ghomi, R. Agarwal, P. | Cogn Behav Neurol | 2022 | |
| The effect of baseline cognition and delirium on long-term cognitive impairment and mortality: a prospective population-based study | Tsui, A. Searle, S. D. Bowden, H. Hoffmann, K. Hornby, J. Goslett, A. Weston-Clarke, M. Howes, L. H. Street, R. Perera, R. Taee, K. Kustermann, C. Chitalu, P. Razavi, B. Magni, F. Das, D. Kim, S. Chaturvedi, N. Sampson, E. L. Rockwood, K. Cunningham, C. E | Lancet Healthy Longev | 2022 | |
| Delirium with visual hallucinations induced by low-dose olanzapine | Takeuchi, N. Makino, T. Nishihara, M. | Psychogeriatrics | 2022 |
*Antipsychotic Agents/adverse effects |