Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Risk factors for postoperative delirium in frail elderly patients undergoing on-pump cardiac surgery and development of a prediction model-a prospective observational study
Authors
Ding, Y. Gao, J. Ge, Y. Huang, T. Zhang, Y.
Year
2024
Journal
Front Cardiovasc Med
Abstract

BACKGROUND: To identify the risk factors for postoperative delirium (POD) after cardiac surgery in frail elderly patients and develop a receiver operating characteristic (ROC) prediction model to confirm the effectiveness. METHODS: This was a prospective observational study, patients were assessed preoperatively according to the frailty index (FI) scale. Cerebral (SctO(2)) was assessed at different time points using near-infrared spectroscopy (NIRS). On the basis of the occurrence of POD within 7 days after surgery, patients were divided into POD and non-POD groups. Risk factors were analyzed using logistic regression analysis, while their predictive values were evaluated using the receiver operating characteristic curve analysis. RESULTS: POD was significantly associated with frailty, lower preoperative MMSE scores, hyperlipidemia, diabetes, cerebrovascular disease, lower hemoglobin level, lower albumin level, longer operation time, longer CPB time, lower SctO(2) at T5, and lower SctO(2baseline) (P < 0.05). SrtO(2) and SmtO(2) did not differ significantly between groups. FI, preoperative MMSE score, and operation time as independent risk factors (P < 0.05). Significant predictive value was demonstrated in all 3 variables (P < 0.001; respectively). Among them, high sensitivity and specificity were observed with the FI (cut-off value 0.27, sensitivity 75%, specificity 73.5%) and operation time (cut-off value 237.5, sensitivity 62.5%, specificity 78.6%). CONCLUSIONS: The FI, preoperative MMSE score, and operation time were independent risk factors for POD in elderly patients after cardiac surgery, with high predictive value observed with the FI and operation time. Cerebral oxygen saturation was associated with POD but was not an independent risk factor. CLINICAL TRIAL REGISTRATION: Chinese Clinical Trail Registry, No: chictr2200056038.

PMID

PMID: 39171326

PMCID: PMC11335481

Keywords

cardiac surgery
cardiopulmonary bypass
frailty
near-infrared spectroscopy
postoperative delirium
tissue oxygen saturation

Page(s)
Issue

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Total Records Found: 6347, showing 100 per page
TitleAuthorsJournalYearKeywords
Association between smoking and postoperative delirium in surgical patients with pulmonary hypertension: a secondary analysis of a cohort study Zhou, S. Shi, S. Xie, C. Chen, G. BMC Psychiatry 2022

Cohort Studies
*Delirium/epidemiology
Humans
*Hypertension, Pulmonary/complications
Postoperative Complications/epidemiology/etiology
Prospective Studies
Smoking/adverse effects
*Postoperative delirium
*Pulmonary hypertension
*Smoking

Comorbidity patterns in institutionalized older adults affected by dementia Zazzara, M. B. Vetrano, D. L. Carfì, A. Liperoti, R. Damiano, C. Onder, G. Alzheimers Dement (Amst) 2022

care pathways
dementia comorbidities
nursing homes
older adults
personalized medicine

The Impact of Perioperative and Predisposing Risk Factors on the Development of Postoperative Delirium and a Possible Gender Difference Wittmann, M. Kirfel, A. Jossen, D. Mayr, A. Menzenbach, J. Geriatrics (Basel) 2022

gender difference
older adults
postoperative delirium
risk factors

Four-in-One: A Comprehensive Checklist for the Assessment of Pain, Undersedation, Iatrogenic Withdrawal and Delirium in the PICU: A Delphi Study van Dijk, M. Ista, E. Front Pediatr 2022

Iws
delirium
distress
pain assessment
pediatric intensive care unit
undersedation
commercial or financial relationships that could be construed as a potential
conflict of interest.

Analgesia, Sedation, Paralytics, Delirium, and Iatrogenic Withdrawal Valentine, K. Kummick, J. Pediatr Clin North Am 2022

*Analgesia
Child
Conscious Sedation
Critical Care
Critical Illness/therapy
*Delirium/chemically induced/drug therapy
Humans
Hypnotics and Sedatives/adverse effects
Iatrogenic Disease
Pain/drug therapy
Pain Management
*Critical care pediatrics
*Delirium
*Paralytics
*Sedation
*Withdrawal

Antipsychotic prescribing in people admitted to hospital with dementia or delirium Tumusiime, W. A. Hardman, C. J. Breen, J. L. Australas J Ageing 2022

*Antipsychotic Agents/therapeutic use
*Delirium/diagnosis/drug therapy
*Dementia/diagnosis/drug therapy
Hospitalization
Hospitals
Humans
Retrospective Studies
antipsychotic
delirium
dementia
hospital
psychotropic

Breaking barriers in postoperative delirium Terrando, N. Akassoglou, K. Br J Anaesth 2022

biomarker
blood–brain barrier
cerebrospinal fluid
delirium
fibrinogen
neuroinflammation

The Relationship Between Suboptimal Social Networks and Postoperative Delirium: The PNDABLE Study Tang, X. Yv, H. Wang, F. Wang, J. Liu, S. Wu, X. Dong, R. Lin, X. Wang, B. Bi, Y. Front Aging Neurosci 2022

cerebrospinal fluid
lifestyle
mediating effect
postoperative delirium
social networks
commercial or financial relationships that could be construed as a potential
conflict of interest.

Delirium incidence and risk factors in patients undergoing non-invasive ventilation for acute respiratory failure: a multicenter observational trial Tabbì, L. Tonelli, R. Comellini, V. Dongilli, R. Sorgentone, S. Spacone, A. Paonessa, M. C. Sacchi, M. Falsini, L. Boni, E. Ribuffo, V. Bruzzi, G. Castaniere, I. Fantini, R. Marchioni, A. Pisani, L. Nava, S. Clini, E. Minerva Anestesiol 2022
The association between Monocyte-to-Lymphocyte ratio and postoperative delirium in ICU patients in cardiac surgery Su, X. Wang, J. Lu, X. J Clin Lab Anal 2022

inflammatory markers
medical information Mart for intensive care-III
monocyte-to-lymphocyte ratio
postoperative delirium

Development of a non-pharmacologic delirium management bundle in paediatric intensive care units Stenkjaer, R. L. Herling, S. F. Egerod, I. Weis, J. van Dijk, M. Kudchadkar, S. R. Ramelet, A. S. Ista, E. Nurs Crit Care 2022

delirium
delphi study
management
non-pharmacological
paediatric intensive care unit

Delirium in hospitalised adults with acute burns - A systematic review Stanley, G. H. M. Barber, A. R. J. O'Brien, A. M. Hamill, C. Boardman, G. Frear, C. C. Edgar, D. W. Seymour, H. Wood, F. M. Burns 2022

Burns
Delirium
Intensive care
Meta-analysis
Systematic review

Delirium associated with buprenorphine use in cardiac surgery: A retrospective cohort study Selvaraj, T. Thangavel, P. Siddhaarth, K. Indian J Anaesth 2022

Aged
buprenorphine
coronary artery bypass off-pump
delirium
postoperative pain

Influence of perioperative dexmedetomidine on the incidence of postoperative delirium in adult patients undergoing cardiac surgery Patel, M. Onwochei, D. N. Desai, N. Br J Anaesth 2022

Adult
Bradycardia/epidemiology
*Cardiac Surgical Procedures/adverse effects
*Delirium/epidemiology/prevention & control
*Dexmedetomidine/therapeutic use
Humans
Incidence
Postoperative Complications/epidemiology/prevention & control
*cardiac surgery
*confusion assessment method
*delirium
*dexmedetomidine
*systematic review

Association Between Implementation of a Geriatric Trauma Clinical Pathway and Changes in Rates of Delirium in Older Adults With Traumatic Injury Park, C. Bharija, A. Mesias, M. Mitchell, A. Krishna, P. Storr-Street, N. Brown, A. Martin, M. Lu, A. C. Staudenmayer, K. L. JAMA Surg 2022
Intraoperative hyperoxygenation may negatively affect postoperative cognitive functions in coronary artery bypass graft operations: A randomized controlled study Onur, T. Karaca, Ü Ata, F. Sayan, H. E. Onur, A. Yilmaz, C. Balkaya, A. N. Eriş, C. J Card Surg 2022

cardiopulmonary bypass
cognitive function
hyperoxia
near-infrared
postoperative complications
spectroscopy

Investigation of Risk Factors for Postoperative Delirium after Transcatheter Aortic Valve Implantation: A Retrospective Study Ogata, Y. Kobayashi, N. Yamauchi, M. J Clin Med 2022

aortic stenosis
postoperative delirium
transcatheter aortic valve implantation

Mobilization in the evening to prevent delirium: A pilot randomized trial Nydahl, P. McWilliams, D. Weiler, N. Borzikowsky, C. Howroyd, F. Brobeil, A. Lindner, M. von Haken, R. Nurs Crit Care 2022

Critical Care
*Delirium/prevention & control
Humans
*Intensive Care Units
Pilot Projects
Respiration, Artificial/adverse effects
delirium
early mobilization
intensive care unit
prevention
rehabilitation

Delirium on stroke units: a prospective, multicentric quality-improvement project Nydahl, P. Baumgarte, F. Berg, D. Bergjan, M. Borzikowsky, C. Franke, C. Green, D. Hannig, A. Hansen, H. C. Hauss, A. Hansen, U. Istel, R. Krämer, N. Krause, K. Lohrmann, R. Mohammadzadeh-Vazifeh, M. Osterbrink, J. Palm, F. Petersen, T. Schöller, B. Sto J Neurol 2022

*Delirium/diagnosis/epidemiology/etiology
Humans
Incidence
Postoperative Complications/epidemiology
Prospective Studies
Quality Improvement
Registries
Risk Factors
*Stroke/complications/therapy
Delirium
Encephalopathy
Quality-improvement
Stroke

The relationship of acute delirium with cognitive and psychiatric symptoms after stroke: a longitudinal study Nerdal, V. Gjestad, E. Saltvedt, I. Munthe-Kaas, R. Ihle-Hansen, H. Ryum, T. Lydersen, S. Grambaite, R. BMC Neurol 2022

Aged
Cognition
*Cognitive Dysfunction/etiology
*Delirium/diagnosis/epidemiology/etiology
Female
Humans
Longitudinal Studies
Male
Neuropsychological Tests
Prospective Studies
*Stroke/diagnosis
Anxiety
Cerebrovascular event
Cognitive dysfunction
Confusion
Depression
Mental status and dementia tests
is associate editor in BMC Neurology. None of the other authors have any
conflicts of interests to declare.

Alpha-2-adrenergic receptor agonists for the prevention of delirium and cognitive decline after open heart surgery (ALPHA2PREVENT): protocol for a multicentre randomised controlled trial Neerland, B. E. Busund, R. Haaverstad, R. Helbostad, J. L. Landsverk, S. A. Martinaityte, I. Norum, H. M. Ræder, J. Selbaek, G. Simpson, M. R. Skaar, E. Skjærvold, N. K. Skovlund, E. Slooter, A. J. Svendsen Ø, S. Tønnessen, T. Wahba, A. Zetterberg, H. BMJ Open 2022

Adrenergic alpha-2 Receptor Agonists/therapeutic use
Aged
*Cardiac Surgical Procedures/adverse effects
Clonidine/therapeutic use
*Cognitive Dysfunction/etiology
*Delirium/diagnosis/etiology/prevention & control
*Dexmedetomidine/therapeutic use
Double-Blind Method
*Frailty/complications
Humans
Multicenter Studies as Topic
Randomized Controlled Trials as Topic
adult anaesthesia
cardiac surgery
delirium & cognitive disorders
geriatric medicine

Does modulation of glymphatic system reduce delirium via waste clearance? Naaz, S. Asghar, A. J Anaesthesiol Clin Pharmacol 2022
Delirium in elderly postoperative patients: A prospective cohort study Muzzana, C. Mantovan, F. Huber, M. K. Trevisani, K. Niederbacher, S. Kugler, A. Ausserhofer, D. Nurs Open 2022

delirium
general surgery
nursing assessment
outcome assessment health care
postoperative complications
postoperative delirium

Antimicrobial neurotoxicity: an under-recognised cause of delirium Moynan, D. Maqbool, E. de Barra, E. Acute Med 2022

Aged
Anti-Bacterial Agents/adverse effects
*Brain Diseases/chemically induced/diagnosis/drug therapy
*Delirium/chemically induced/diagnosis
Humans
Male
*Myoclonus/chemically induced/drug therapy

CORR Insights®: Does the SORG Orthopaedic Research Group Hip Fracture Delirium Algorithm Perform Well on an Independent Intercontinental Cohort of Patients With Hip Fractures Who Are 60 Years or Older? Michelson, J. D. Clin Orthop Relat Res 2022
Drug Choice for Hyperactive Delirium in Terminally-Ill Cancer Patients: A Nationwide Survey Matsuda, Y. Morita, T. Oya, K. Tagami, K. Naito, A. S. Kashiwagi, H. Otani, H. J Pain Symptom Manage 2022

cancer
hyperactive delirium
pharmacological treatment
terminal delirium

Implementing delirium screening in the emergency department: a quality improvement project Martin, L. Lyons, M. Patton, A. O. Driscoll M McLoughlin, K. Hannon, E. Deasy, C. BMJ Open Qual 2022

Aged
*Delirium/diagnosis/prevention & control
Emergency Service, Hospital
Humans
Mass Screening
*Quality Improvement
Total Quality Management
Emergency department
Healthcare quality improvement
Quality improvement

Evaluation of the association of anticholinergic burden and delirium in older hospitalised patients - A cohort study comparing 19 anticholinergic burden scales Lisibach, A. Gallucci, G. Benelli, V. Kälin, R. Schulthess, S. Beeler, P. E. Csajka, C. Lutters, M. Br J Clin Pharmacol 2022

Doss
anticholinergic burden
delirium during hospitalisation
older patients

Demand Ischemia as a Predictor of Mortality in Older Patients With Delirium Kumar, M. Patil, S. Godoy, L. D. C. Kuo, C. L. Swede, H. Kuchel, G. A. Chen, K. Front Cardiovasc Med 2022

clinical outcomes
coronary artery disease
delirium
demand ischemia
mortality
commercial or financial relationships that could be construed as a potential
conflict of interest.

Structured Delirium Management in the Hospital Krämer, J. Nolte, K. Zupanc, L. Schnitker, S. Roos, A. Göpel, C. Cid, J. S. Eichler, K. Hooven, T. V. D. Hempel, G. Pavenstädt, H. J. Klaas, C. Gosheger, G. Raschke, M. J. Wiendl, H. Duning, T. Dtsch Arztebl Int 2022

Activities of Daily Living
Aged
*Delirium/diagnosis/prevention & control
Hospitalization
Hospitals
Humans
Length of Stay

A machine learning approach to identifying delirium from electronic health records Kim, J. H. Hua, M. Whittington, R. A. Lee, J. Liu, C. Ta, C. N. Marcantonio, E. R. Goldberg, T. E. Weng, C. JAMIA Open 2022

Confusion Assessment Method for the Intensive Care Unit (CAM-ICU)
delirium
electronic health records
logistic regression
machine learning model

Effects of nonpharmacological interventions on sleep improvement and delirium prevention in critically ill patients: A systematic review and meta-analysis Kang, J. Cho, Y. S. Lee, M. Yun, S. Jeong, Y. J. Won, Y. H. Hong, J. Kim, S. Aust Crit Care 2022

Critical care
Critical care nursing
Delirium
Intensive care units
Meta-analysis
Sleep
Systematic review

A machine-learning model to predict postoperative delirium following knee arthroplasty using electronic health records Jung, J. W. Hwang, S. Ko, S. Jo, C. Park, H. Y. Han, H. S. Lee, M. C. Park, J. E. Ro, D. H. BMC Psychiatry 2022

*Arthroplasty, Replacement, Knee/adverse effects
*Delirium/diagnosis/epidemiology/etiology
Electronic Health Records
Humans
Machine Learning
Retrospective Studies
Risk Assessment
Delirium
Neurologic disorder
Prediction
Preoperative model
Total knee arthroplasty

Tranexamic Acid and the Risk of Delirium after Off-Pump Surgery Hulde, N. Zittermann, A. Deutsch, M. A. Gummert, J. F. von Dossow, V. Koster, A. Thorac Cardiovasc Surg 2022
Early Serum Metabolism Profile of Post-operative Delirium in Elderly Patients Following Cardiac Surgery With Cardiopulmonary Bypass Huang, H. Han, J. Li, Y. Yang, Y. Shen, J. Fu, Q. Chen, Y. Front Aging Neurosci 2022

cardiopulmonary bypass
lipid
metabolomics
perioperative neurocognitive disorder
phosphatidylinositol
post-operative delirium
commercial or financial relationships that could be construed as a potential
conflict of interest.

Delirium Item Bank: Utilization to Evaluate and Create Delirium Instruments Helfand, B. K. I. Tommet, D. Detroyer, E. Milisen, K. Adamis, D. Metzger, E. D. Marcantonio, E. R. Boudreaux, E. D. Inouye, S. K. Jones, R. N. Dement Geriatr Cogn Disord 2022

Aged
*Delirium/diagnosis/etiology
Diagnostic and Statistical Manual of Mental Disorders
Humans
Psychometrics
Reproducibility of Results
Sensitivity and Specificity
*Delirium
*Item bank
*Item response theory
*Measurement
*Psychometrics

Low Dose Antipsychotics for the Treatment of Delirium in Hospitalized Elderly Patients and Their Effects on QTc Interval Heidari, S. Kargar, M. J Pharm Pract 2022

adverse drug events
antipsychotic agents
cardiac arrhythmia
delirium
geriatric psychiatry

Melatonin and Its Analogs for Prevention of Post-cardiac Surgery Delirium: A Systematic Review and Meta-Analysis Han, Y. Tian, Y. Wu, J. Zhu, X. Wang, W. Zeng, Z. Qin, Z. Front Cardiovasc Med 2022

cardiac
melatonin
meta-analysis
postoperative delirium
ramelteon
systematic review
commercial or financial relationships that could be construed as a potential
conflict of interest.

The Role of Acetylcholinesterase Inhibitors in the Treatment of Prolonged Postelectroconvulsive Therapy Delirium Gutowski, B. Bomasang-Layno, E. Case Rep Psychiatry 2022
Risk factors for delirium in elderly patients after lumbar spinal fusion Gold, C. Ray, E. Christianson, D. Park, B. Kournoutas, I. A. Kahn, T. A. Perez, E. A. Berger, J. I. Sander, K. Igram, C. A. Pugely, A. Olinger, C. R. Carnahan, R. Chen, P. F. Mueller, R. Hitchon, P. Howard, M. A. Banks, M. Sanders, R. D. Woodroffe, R. W. Clin Neurol Neurosurg 2022

Geriatric spine surgery
Pain
Postoperative cognitive dysfunction
Postoperative delirium
Spinal fusion

Instruments to Identify Delirium in Patients Recovering From Anesthesia: A Scoping Review Gnatta, J. R. Cavassana, T. M. Nascimento, A. S. D. Poveda, V. B. J Perianesth Nurs 2022

delirium
postanesthesia nursing
postoperative cognitive complications
recovery room

Identifying Patients With Delirium Based on Unstructured Clinical Notes: Observational Study Ge, W. Alabsi, H. Jain, A. Ye, E. Sun, H. Fernandes, M. Magdamo, C. Tesh, R. A. Collens, S. I. Newhouse, A. Mvr Moura, L. Zafar, S. Hsu, J. Akeju, O. Robbins, G. K. Mukerji, S. S. Das, S. Westover, M. B. JMIR Form Res 2022

clinical notes
delirium
electronic health records
machine learning
natural language processing

Predictors of post-stroke delirium incidence and duration: results of a prospective observational study using high frequency delirium screening Fleischmann, R. Andrasch, T. Warwas, S. Kunz, R. Gross, S. Witt, C. Ruhnau, J. Vogelgesang, A. Ulm, L. Mengel, A. von Sarnowski, B. Int J Stroke 2022

Acute stroke therapy
Risk factors
cognitive impairment
ischemic stroke
pain
post-stroke delirium
post-stroke infection

Italian Version of the Cornell Assessment of Pediatric Delirium: Evaluation of the Scale Reliability and Ability to Detect Delirium Compared to Pediatric Intensive Care Unit Physicians Clinical Evaluation Fazio, P. C. Daverio, M. Masola, M. D'Angelo, I. Frison, S. Zaggia, C. Simeone, S. Pucciarelli, G. Gregori, D. Comoretto, R. Amigoni, A. Front Pediatr 2022

Capd
Cornell Assessment of Pediatric Delirium
Picu
pediatric delirium
pediatric intensive care unit
commercial or financial relationships that could be construed as a potential
conflict of interest.

Regional anesthesia techniques and postoperative delirium: systematic review and meta-analysis Fanelli, A. Balzani, E. Memtsoudis, S. Abdallah, F. W. Mariano, E. R. Minerva Anestesiol 2023

Aged
*Anesthesia, Conduction/methods
Anesthesia, Local
*Delirium/epidemiology/etiology/prevention & control
*Hip Fractures/surgery
Humans

Delirium with delayed diagnosis of hereditary coproporphyria Eroglu, S. Birsenogul, I. Clin Case Rep 2022

atrial fibrillation
delirium
porphyria

The Preventive Effect of Transcutaneous Electrical Acupoint Stimulation on Postoperative Delirium in Elderly Patients with Time Factors: A Randomized Trial Ding, L. Ning, J. Guo, Y. Wang, Q. Kou, S. Ke, H. Zhou, R. Yu, B. J Integr Complement Med 2022

inflammation response
neuron-specific enolation
postoperative delirium
transcutaneous electrical acupoint stimulation
tumor necrosis factor-α

Prophylactic use of ramelteon for delirium in hospitalized patients: A systematic review and meta-analyses Dang, V. Mansukhani, M. P. Wang, Z. Vesely, E. K. Kolla, B. P. J Acad Consult Liaison Psychiatry 2022

Delirium
prevention
ramelteon

Longest and largest cohort study of delirium to date reinforces association while causation remains elusive Cunningham, E. J Neurol Neurosurg Psychiatry 2022

Cognition
Dementia

Documentation and Diagnosis of Delirium in Parkinson's Disease Cullinan, R. J. Richardson, S. J. Yarnall, A. J. Burn, D. J. Allan, L. M. Lawson, R. A. Acta Psychiatr Scand 2022

Confusion
Delirium
Diagnosis
Parkinson Disease

Avoiding pitfalls in the treatment of delirium Chuang, Y. C. Lin, C. Y. Wang, J. K. Aust N Z J Psychiatry 2022

*Delirium/drug therapy
Humans

Less pharmacotherapy is more in delirium Chou, S. T. Pogach, M. Rock, L. K. Intensive Care Med 2022

*Antipsychotic Agents/therapeutic use
*Delirium/drug therapy
Humans

Accuracies of Training Labels and Machine Learning Models: Experiments on Delirium and Simulated Data Cheng, Y. Shao, Y. Rudolph, J. Weir, C. R. Sahlmann, B. Zeng-Treitler, Q. Stud Health Technol Inform 2022

*Delirium
Humans
*Machine Learning
Support Vector Machine
delirium
weak supervised learning

E4BP4 Coordinates Circadian Control of Cognition in Delirium Chen, M. Zhang, L. Shao, M. Du, J. Xiao, Y. Zhang, F. Zhang, T. Li, Y. Zhou, Q. Liu, K. Wang, Z. Wu, B. Adv Sci (Weinh) 2022

E4bp4
Erk1/2
circadian rhythm
delirium
microglia

Association Between Anesthetics and Postoperative Delirium in Elderly Patients Undergoing Spine Surgery: Propofol Versus Sevoflurane Chang, J. E. Min, S. W. Kim, H. Won, D. Lee, J. M. Kim, T. K. Kim, C. Hwang, J. Y. Global Spine J 2022

anesthesia
delirium
elderly
propofol
sevoflurane

Validation of a delirium predictive model in patients admitted to surgical intensive care units: a multicentre prospective observational cohort study Chaiwat, O. Chittawatanarat, K. Mueankwan, S. Morakul, S. Dilokpattanamongkol, P. Thanakiattiwibun, C. Siriussawakul, A. BMJ Open 2022

Adult
Aged
Aged, 80 and over
Critical Care
Critical Illness
*Delirium/diagnosis/epidemiology/etiology
Humans
*Intensive Care Units
Middle Aged
Prospective Studies
adult intensive & critical care
delirium & cognitive disorders
intensive & critical care

Lidocaine Infusion for the Management of Postoperative Pain and Delirium (LIMPP): protocol for a randomised control trial Buren, M. A. Theologis, A. Zuraek, A. Behrends, M. Clark, A. J. Leung, J. M. BMJ Open 2022

Aged
Analgesics, Opioid/adverse effects
*Delirium/drug therapy/etiology/prevention & control
Double-Blind Method
Humans
*Lidocaine/therapeutic use
Pain, Postoperative/complications/drug therapy/prevention & control
Randomized Controlled Trials as Topic
Anaesthesia in orthopaedics
Geriatric medicine
Neurosurgery
Pain management
Spine

Factors influencing resilience to postoperative delirium in adults undergoing elective orthopaedic surgery Bowman, E. M. L. Cardwell, C. McAuley, D. F. McGuinness, B. Passmore, A. P. Beverland, D. Zetterberg, H. Schott, J. M. Cunningham, E. L. Br J Surg 2022
Delirium prediction in the ICU: designing a screening tool for preventive interventions Bhattacharyya, A. Sheikhalishahi, S. Torbic, H. Yeung, W. Wang, T. Birst, J. Duggal, A. Celi, L. A. Osmani, V. JAMIA Open 2022

artificial intelligence
clinical decision support
delirium
machine learning
nursing assessment
predictive modeling

Regional vs General Anesthesia and Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery Zhu, Z. Cao, P. Lin, L. Jama 2022

Aged
*Anesthesia, Conduction/adverse effects
*Anesthesia, General/adverse effects
*Delirium/epidemiology/etiology
*Hip Fractures/epidemiology/surgery
Humans
Incidence
Postoperative Complications/epidemiology/etiology

Melatonin intervention to prevent delirium in hospitalized patients: A meta-analysis You, W. Fan, X. Y. Lei, C. Nie, C. C. Chen, Y. Wang, X. L. World J Clin Cases 2022

Delirium
Melatonin
Meta-analysis
Prevention
Randomized controlled trial

Preoperative Low Physical Activity is a Predictor of Postoperative Delirium in Patients with Gastrointestinal Cancer: A Retrospective Study Yanagisawa, T. Tatematsu, N. Horiuchi, M. Migitaka, S. Yasuda, S. Itatsu, K. Kubota, T. Sugiura, H. Asian Pac J Cancer Prev 2022

Activities of Daily Living
*Delirium/diagnosis/etiology
Exercise
*Gastrointestinal Neoplasms/complications/surgery
Humans
Retrospective Studies
Gastrointestinal cancer
physical activity
postoperative delirium

What is It Like to be Delirious? Wijdicks, E. F. M. Rabinstein, A. A. Neurocrit Care 2022

Definitions
Delirium
Encephalopathy
Hallucinations
Pathophysiology

Impact of Pain, Agitation, and Delirium Bundle on Delirium and Cognitive Function Wang, X. P. Lv, D. Chen, Y. F. Chen, N. Li, X. D. Xu, C. F. Li, Y. Tian, L. J Nurs Res 2022
Regional vs General Anesthesia and Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery Uzoigwe, C. E. Campbell-Jones, F. Jama 2022

Aged
*Anesthesia, Conduction/adverse effects
*Anesthesia, General/adverse effects
*Delirium/epidemiology/etiology
*Hip Fractures/epidemiology/surgery
Humans
Incidence
Postoperative Complications/epidemiology/etiology

Improving delirium screening in older adults at the Royal United Hospital, Bath Trew, C. A. Cross, R. Howell, K. Dyer, C. Br J Hosp Med (Lond) 2022

Aged
*Delirium/diagnosis/prevention & control
Hospitalization
Hospitals, University
Humans
Inpatients
Mass Screening
Audit
Delirium
Quality improvement
Screening

Assessing prevalence and independent predictors of postoperative delirium in patients with head and neck cancer Tian, T. Xue, F. S. Shao, L. J. Z. Hu, B. Br J Oral Maxillofac Surg 2022

*Delirium/epidemiology/etiology
*Head and Neck Neoplasms/surgery
Humans
Postoperative Complications/epidemiology
Prevalence
Risk Factors
Head and neck cancer
Postoperative care
Postoperative delirium
Prediction
Risk factors

Delirium due to hip fracture is associated with activated immune-inflammatory pathways and a reduction in negative immunoregulatory mechanisms Thisayakorn, P. Thipakorn, Y. Tantavisut, S. Sirivichayakul, S. Maes, M. BMC Psychiatry 2022

Aged
Biomarkers
Cytokines
*Delirium/complications
*Hip Fractures/complications/surgery
Humans
Tumor Necrosis Factor-alpha
Delirium
Hip fracture
Inflammation
Neurocognition
Neuroimmune

Retrospective evaluation of a delirium order set utilizing nonpharmacologic and pharmacologic interventions for the treatment of delirium in medical intensive care unit patients Taylor, A. D. Chen, A. Reddy, A. J. Lewandowski, A. Torbic, H. Am J Health Syst Pharm 2022

Adolescent
Adult
*Antipsychotic Agents/therapeutic use
*Delirium/diagnosis/drug therapy
Humans
Intensive Care Units
Patient Discharge
Retrospective Studies
*antipsychotic
*central nervous system
*clinical pathway
*critical care
*delirium
*drug utilization

Prevention of dexmedetomidine on postoperative delirium and early postoperative cognitive dysfunction in elderly patients undergoing hepatic lobectomy Tang, Y. Wang, Y. Kong, G. Zhao, Y. Wei, L. Liu, J. Zhong Nan Da Xue Xue Bao Yi Xue Ban 2022

Aged
Aged, 80 and over
Bradycardia
*Cognitive Dysfunction/etiology/prevention & control
*Delirium/drug therapy/epidemiology/prevention & control
*Dexmedetomidine/therapeutic use
Humans
*Hypotension/complications/drug therapy
Interleukin-10
Middle Aged
*Postoperative Cognitive Complications/prevention & control
Postoperative Complications/epidemiology
Prospective Studies
Tumor Necrosis Factor-alpha
dexmedetomidine
elderly patients
hepatic lobectomy
postoperative cognitive dysfunction
postoperative delirium

Prevalence, clinical features, and risk factors of delusions in patients with delirium Tachibana, M. Inada, T. Ichida, M. Ozaki, N. Int J Geriatr Psychiatry 2022
Effect of sedative premedication with oral midazolam on postanesthesia care unit delirium in older adults: a secondary analysis following an uncontrolled before-after design Stuff, K. Kainz, E. Kahl, U. Pinnschmidt, H. Beck, S. von Breunig, F. Nitzschke, R. Funcke, S. Zöllner, C. Fischer, M. Perioper Med (Lond) 2022

Anesthesia
Benzodiazepines
Delirium
Perioperative care
Premedication

Associations of Smoking With Delirium and Opioid Use in Older Adults With Traumatic Hip Fracture Salottolo, K. Meinig, R. Fine, L. Kelly, M. Madayag, R. Ekengren, F. Tanner, A., 2nd Bar-Or, D. J Am Acad Orthop Surg Glob Res Rev 2022

Aged
Analgesics, Opioid/therapeutic use
*Delirium/epidemiology/etiology/prevention & control
*Hip Fractures/epidemiology/etiology/surgery
Humans
*Opioid-Related Disorders/complications/drug therapy
Pain, Postoperative/drug therapy
Prospective Studies
Smoking/adverse effects/epidemiology

Impact of delirium on mortality in patients hospitalized for heart failure Ritchie, C. Walters, R. W. Ramaswamy, S. Alla, V. M. Int J Psychiatry Med 2022

Aged
*Delirium/diagnosis
*Heart Failure/diagnosis/epidemiology
Hospital Mortality
Hospitalization
Humans
Length of Stay
Retrospective Studies
United States/epidemiology
delirium
heart failure
national inpatient sample

Risk for post-operative delirium related to comorbidities in older adult cardiac patients: An integrative review Ramos, M. D. Vergara, F. H. Shackleford, J. Briggs, C. Gomez, C. Mofazali, M. Preston, J. J Clin Nurs 2022

cardiac surgery
comorbidities
older adults
post-operative delirium

Diagnosis and management of delirium in hospital oncology services Ramírez Zuluaga, L. P. Ruano Restrepo, M. I. Osorio Bermúdez, J. D. Díaz Vallejo, J. A. J Geriatr Oncol 2022

*Delirium/diagnosis/etiology/therapy
Humans
*Neoplasms/complications/therapy
Oncology Service, Hospital
Prognosis
*Cancer
*Delirium
*Hospital oncology services

Cognitive Predictors of Delirium on Long-Term Follow-Up after TIA and Stroke: Population-Based Cohort Study Pendlebury, S. T. Thomson, R. J. Welch, S. J. V. Rothwell, P. M. Cerebrovasc Dis 2022

Aged
Cognition
*Cognitive Dysfunction/diagnosis/epidemiology/etiology
Cohort Studies
*Delirium/diagnosis/epidemiology/etiology
Follow-Up Studies
Humans
*Ischemic Attack, Transient/complications/diagnosis/psychology
Neuropsychological Tests
*Stroke/complications/diagnosis
Cognitive impairment
Delirium
Long-term follow-up
TIA and stroke

Plasma neurofilament light chain protein as a predictor of days in delirium and deep sedation, mortality and length of stay in critically ill patients Page, V. J. Watne, L. O. Heslegrave, A. Clark, A. McAuley, D. F. Sanders, R. D. Zetterberg, H. EBioMedicine 2022

Biomarker
Critical care
Delirium
Intensive care
Neurofilament light protein

Feasibility of Machine Learning and Logistic Regression Algorithms to Predict Outcome in Orthopaedic Trauma Surgery Oosterhoff, J. H. F. Gravesteijn, B. Y. Karhade, A. V. Jaarsma, R. L. Kerkhoffs, Gmmj Ring, D. Schwab, J. H. Steyerberg, E. W. Doornberg, J. N. J Bone Joint Surg Am 2022

Algorithms
*Ankle Fractures/surgery
Feasibility Studies
Humans
Logistic Models
Machine Learning
*Orthopedics
Retrospective Studies
*Scaphoid Bone
*Tibial Fractures/surgery

Delirium detection methodologies: Implications for outcome measurement in clinical trials in postoperative delirium Oh, E. S. Rosenberg, P. B. Wang, N. Y. Sieber, F. E. Neufeld, K. J. Int J Geriatr Psychiatry 2022

Aged
*Delirium/epidemiology
Diagnostic and Statistical Manual of Mental Disorders
*Hip Fractures/complications/surgery
Humans
Incidence
Postoperative Complications/diagnosis
*clinical trials
*confusion assessment method (CAM)
*consenus panel diagnosis
*delirium
*hip fracture

Nurse staffing levels are not associated with appearance, duration or solution of delirium in stroke patients Nydahl, P. Meyne, J. Osterbrink, J. Margraf, N. G. Intensive Crit Care Nurs 2022

*Delirium/complications
Humans
*Nurses
*Nursing Staff, Hospital
Personnel Staffing and Scheduling
*Stroke/complications
Workforce
*Delirium
*Encephalopathy
*Personnel Staffing and Scheduling

Regional vs General Anesthesia and Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery Nobuhara, C. Devinney, M., Jr. Berger, M. Jama 2022

Aged
*Anesthesia, Conduction/adverse effects
*Anesthesia, General/adverse effects
*Delirium/epidemiology/etiology
*Hip Fractures/epidemiology/surgery
Humans
Incidence
Postoperative Complications/epidemiology/etiology

Linking Perioperative Medications and Delirium Nathan, N. Anesth Analg 2022

*Delirium/chemically induced/diagnosis
Humans
Perioperative Care
Postoperative Complications
Risk Factors

Prolonged and severe post-electroconvulsive therapy delirium with concurrent clozapine therapy Melnikoff, E. Thomas Johnson, E. Walker, F. Itrat, Q. Jagadheesan, K. Aust N Z J Psychiatry 2022

*Antipsychotic Agents/adverse effects
*Clozapine/adverse effects
Combined Modality Therapy
*Delirium/therapy
*Electroconvulsive Therapy
Humans

'Excited Delirium', acute behavioural disturbance, death and diagnosis McGuinness, T. Lipsedge, M. Psychol Med 2022

Acute behavioural disturbance
coroners
emergency psychiatry
excited delirium
restraints

Effects of non-pharmacologic prevention on delirium in critically ill patients: A network meta-analysis Matsuura, Y. Ohno, Y. Toyoshima, M. Ueno, T. Nurs Crit Care 2022

acute encephalopathy
delirium
intensive care unit
network meta-analysis
systematic review

Melatonin Receptor Agonists for the Prevention of Delirium: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials Maneeton, B. Kongsaengdao, S. Maneeton, N. Likhitsathian, S. Woottiluk, P. Kawilapat, S. Srisurapanont, M. Curr Neuropharmacol 2022

Delirium
Incidence
Melatonin
Melatonin Receptor Agonist
Prevention
Ramelteon

Potential Value of Serum Lipid in the Identication of Postoperative Delirium Undergoing Knee/Hip Arthroplasty: The Perioperative Neurocognitive Disorder and Biomarker Lifestyle Study Lin, Y. Peng, X. Lin, X. Deng, X. Liu, F. Tao, H. Dong, R. Wang, B. Bi, Y. Front Psychiatry 2022

cholesterol
delirium
high-density lipoprotein (HDL)
low-density lipoprotein (LDL)
mediation effect
triglycerides (TG)
commercial or financial relationships that could be construed as a potential
conflict of interest.

Habitual tea consumption and postoperative delirium after total hip/knee arthroplasty in elderly patients: The PNDABLE study Lin, X. Li, X. X. Dong, R. Wang, B. Bi, Y. L. Brain Behav 2022

cholinergic nerve system
elderly
hip/knee arthroplasty
postoperative delirium
tea

Delirium and the risk of developing dementia: a cohort study of 12 949 patients Leighton, S. P. Herron, J. W. Jackson, E. Sheridan, M. Deligianni, F. Cavanagh, J. J Neurol Neurosurg Psychiatry 2022

Dementia
Medicine
Memory
Neuropsychiatry
PSYCHOGERIATRICS

Delirium risk factors analysis post proximal femur fracture surgery in elderly Leigheb, M. De Sire, A. Zeppegno, P. Forni, F. Sgreccia, M. Gagliardi, V. P. Pogliacomi, F. Sabbatini, M. Acta Biomed 2022

Aged
*Delirium/complications/etiology
*Femoral Fractures/epidemiology/surgery
Femur
*Hip Fractures/complications/surgery
Humans
Postoperative Complications/epidemiology/etiology
Risk Factors

A Scoping Review of the Incidence, Predictors, and Outcomes of Delirium Among Critically Ill Stroke Patients Lawson, T. N. Balas, M. C. McNett, M. J Neurosci Nurs 2022

Adult
Critical Illness/psychology
*Delirium/epidemiology/etiology
Humans
Incidence
Intensive Care Units
*Ischemic Stroke
Quality of Life
*Subarachnoid Hemorrhage/complications

Non-Pharmacological Nursing Interventions to Prevent Delirium in ICU Patients-An Umbrella Review with Implications for Evidence-Based Practice Lange, S. Mędrzycka-Dąbrowska, W. Friganovic, A. Oomen, B. Krupa, S. J Pers Med 2022

Icu
delirium
non-pharmacological interventions
systematic review

A decision tree prediction model for a short-term outcome of delirium in patients with advanced cancer receiving pharmacological interventions: A secondary analysis of a multicenter and prospective observational study (Phase-R) Kurisu, K. Inada, S. Maeda, I. Ogawa, A. Iwase, S. Akechi, T. Morita, T. Oyamada, S. Yamaguchi, T. Imai, K. Nakahara, R. Kaneishi, K. Nakajima, N. Sumitani, M. Yoshiuchi, K. Palliat Support Care 2022

Decision Trees
*Delirium/complications/etiology
Humans
*Neoplasms/complications/drug therapy
Palliative Care
Prospective Studies
*Cancer
*Delirium
*Machine learning
*Palliative care
*Psycho-oncology

Postoperative delirium is an independent factor influencing the length of stay of elderly patients in the intensive care unit and in hospital Kirfel, A. Guttenthaler, V. Mayr, A. Coburn, M. Menzenbach, J. Wittmann, M. J Anesth 2022

Aged
Aged, 80 and over
*Delirium/diagnosis/epidemiology/etiology
Hospitals, University
Humans
Intensive Care Units
Length of Stay
*Postoperative Complications/epidemiology/therapy
Risk Factors
Elderly patients
Postoperative delirium

Cost-effectiveness of clinical interventions for delirium: A systematic literature review of economic evaluations Kinchin, I. Edwards, L. Hosie, A. Agar, M. Mitchell, E. Trepel, D. Acta Psychiatr Scand 2022

cost-effectiveness
delirium
economic evaluation
intervention
quality of evidence
review

Effects of non-pharmacological interventions for preventing delirium in general ward inpatients: A systematic review & meta-analysis of randomized controlled trials Kim, Y. H. Kim, N. Y. Ryu, S. PLoS One 2022

Adult
*Delirium/epidemiology/prevention & control
Hospitalization
Humans
*Inpatients
Patients’ Rooms
Randomized Controlled Trials as Topic

Analysis of the Incidence and Risk Factors of Postoperative Delirium in Patients With Degenerative Cervical Myelopathy Kim, N. Kim, T. H. Oh, J. K. Lim, J. Lee, K. U. Kim, S. W. Neurospine 2022

Cervical myelopathy
Delirium
Laminoplasty
Postoperative care

Intraoperative low tidal volume ventilation and the risk of ICD-10 coded delirium and the use for antipsychotic medications Karalapillai, D. Weinberg, L. Neto, A. S. Peyton, P. J. Ellard, L. Hu, R. Pearce, B. Tan, C. Story, D. O'Donnell, M. Hamilton, P. Oughton, C. Galtieri, J. Appu, S. Wilson, A. Eastwood, G. Bellomo, R. Jones, D. A. BMC Anesthesiol 2022

Adult
Aged
*Antipsychotic Agents/adverse effects
*Delirium/chemically induced/epidemiology
Female
Humans
International Classification of Diseases
Male
Middle Aged
Positive-Pressure Respiration/adverse effects
Postoperative Complications/epidemiology/etiology
Respiration, Artificial
Tidal Volume
Delirium
Postoperative
Surgery
Tidal volume

Falling for It: Of Falls, Families, and Delirium Jiménez, J. V. Hyzy, R. C. Crit Care Med 2022

*Accidental Falls
*Delirium/epidemiology/etiology
Fear
Humans