Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Delirium in the ICU: how much do we know? A narrative review
Authors
Liu, S. B. Wu, H. Y. Duan, M. L. Yang, R. L. Ji, C. H. Liu, J. J. Zhao, H.
Year
2024
Journal
Ann Med
Abstract

Delirium in critical ill patients is a complex and common neurological syndrome in the intensive care unit (ICU) that is caused by a range of structural or functional abnormalities. ICU Delirium is associated with reduced compliance, prolonged hospital stays, greater use or delayed withdrawal of sedatives, higher rates and durations of mechanical ventilation, and higher rates of mortality. The aetiology and pathogenesis of ICU delirium are unclear, and the lack of better prediction, prevention, and treatment measures leads to a non-standardized control of delirium. By searching the relevant literature, we aim in this narrative review to describe progress in the pathogenesis, predictive biomarkers, diagnosis, and treatment of ICU delirium.

PMID

PMID: 39308447

PMCID: PMC11421129

Keywords

*Delirium/diagnostic imaging/pathology/therapy
*Intensive Care Units/statistics & numerical data
Nervous System Diseases/diagnostic imaging
Biomarkers
Metabolic Diseases/diagnosis
Humans
Delirium
diagnosis
intensive care unit
treatment

Page(s)
Issue

Search:
Total Records Found: 6272, showing 100 per page
TitleAuthorsJournalYearKeywords
Emergence delirium after intracranial neurosurgery- a prospective cohort study Bharadwaj, S. Konar, S. Akash, V. S. Gopalakrishna, K. N. Chakrabarti, D. Kamath, S. J Clin Neurosci 2022

Adolescent
Adult
Anesthesia Recovery Period
*Anesthetics, Inhalation
*Emergence Delirium/epidemiology/etiology
Humans
*Neurosurgery
Prospective Studies
Risk Factors
Emergence delirium
Hyperactive delirium
Hypoactive delirium
Incidence
Neurosurgery
Risk factors

A novel approach for the detection of cognitive impairment and delirium risk in older patients undergoing spine surgery Barreto Chang, O. L. Whitlock, E. L. Arias, A. D. Tsoy, E. Allen, I. E. Hellman, J. Bickler, P. E. Miller, B. Possin, K. L. J Am Geriatr Soc 2022

anesthesia and surgery
cognitive assessment
postoperative delirium
postoperative outcomes

Temporal Variability in Inflammatory Gene Methylation and Delirium in Critically Ill Patients Alexander, S. A. Conley, Y. P. Girard, T. D. McVerry, B. J. Ren, D. Am J Crit Care 2022

Adolescent
*Brain Injuries
Critical Illness
*Delirium/genetics
Female
Humans
Intensive Care Units
Male
Methylation
Respiration, Artificial

Machine Learning-Based Prediction Models for Delirium: A Systematic Review and Meta-Analysis Xie, Q. Wang, X. Pei, J. Wu, Y. Guo, Q. Su, Y. Yan, H. Nan, R. Chen, H. Dou, X. J Am Med Dir Assoc 2022

Machine learning algorithm
delirium
meta-analysis
predictive model
systematic review

Baseline Anxiety and Depression and Risk for ICU Delirium: A Prospective Cohort Study Wu, T. T. Kooken, R. Zegers, M. Ko, S. Bienvenu, O. J. Devlin, J. W. van den Boogaard, M. Crit Care Explor 2022

anxiety
delirium
depression
intensive care
mental disorders
interest.

Preoperative Cognitive Impairment and Postoperative Delirium in Elderly Surgical Patients - a Retrospective Large Cohort Study Weiss, Y. Zac, L. Refaeli, E. Ben-Yishai, S. Zegerman, A. Cohen, B. Matot, I. Ann Surg 2022
Goal-directed therapy based on rScO(2) monitoring in elderly patients with one-lung ventilation: a randomized trial on perioperative inflammation and postoperative delirium Wang, J. Y. Li, M. Wang, P. Fang, P. Trials 2022

Aged
*Delirium/diagnosis/etiology/prevention & control
Goals
Humans
Inflammation/diagnosis/etiology/prevention & control
Lactates
*One-Lung Ventilation/adverse effects
Oxygen
Pain, Postoperative
S100 Calcium Binding Protein beta Subunit
Agitation during awakening
Awakening time
Goal-directed therapy
Inflammatory factors
Lactate
Postoperative delirium
Randomized controlled trial
Regional saturation of cerebral oxygenation

Impact of propofol versus sevoflurane on the incidence of postoperative delirium in elderly patients after spine surgery: study protocol of a randomized controlled trial Wang, J. H. Lv, M. Zhang, H. X. Gao, Y. Chen, T. T. Wan, T. T. Wang, Y. L. Trials 2022

Aged
*Anesthetics, Inhalation/adverse effects
*Delirium/diagnosis/epidemiology/etiology
Humans
Incidence
*Propofol/adverse effects
Randomized Controlled Trials as Topic
Sevoflurane/adverse effects
Delirium
Propofol
Randomized controlled trial
Sevoflurane
Spine surgery

Impact of propofol versus sevoflurane on the incidence of postoperative delirium in elderly patients after spine surgery: study protocol of a randomized controlled trial Wang, J. H. Lv, M. Zhang, H. X. Gao, Y. Chen, T. T. Wan, T. T. Wang, Y. L. Trials 2022

Aged
*Anesthetics, Inhalation/adverse effects
*Delirium/diagnosis/epidemiology/etiology
Humans
Incidence
*Propofol/adverse effects
Randomized Controlled Trials as Topic
Sevoflurane/adverse effects
Delirium
Propofol
Randomized controlled trial
Sevoflurane
Spine surgery

Potential Value of Serum Uric Acid in the Identification of Postoperative Delirium in Geriatric Patients Undergoing Knee Replacement Wang, F. Tang, X. Wang, J. Liu, S. Wu, X. Dong, R. Lin, X. Wang, B. Bi, Y. Front Aging Neurosci 2022

Alzheimer-related biomarkers
postoperative delirium
prediction
risk factor
serum uric acid

Patient Outcomes After Delirium Screening and Incident Alzheimer's Disease or Related Dementias in Skilled Nursing Facilities Vo, Q. T. Koethe, B. Holmes, S. Simoni-Wastila, L. Briesacher, B. A. J Gen Intern Med 2022

Alzheimer’s disease
Medicare
delirium
dementia
skilled nursing

Delirium in head trauma: looking for a culprit Villani, E. R. Franza, L. Cianci, R. Rev Recent Clin Trials 2022

Delirium
Falls
Geriatrics
Head trauma
Inflammation
Trauma

Timing, Threshold, and Duration of Intraoperative Hypotension in Cardiac Surgery: Their Associations With Postoperative Delirium Ushio, M. Egi, M. Fujimoto, D. Obata, N. Mizobuchi, S. J Cardiothorac Vasc Anesth 2022

Cardiac valvular surgery
Intraoperative hypotension
Post cardiopulmonary bypass
Postoperative delirium
Threshold of mean arterial pressure

Detecting delirium in nursing home residents using the Informant Assessment of Geriatric Delirium (I-AGeD): a validation pilot study Urfer Dettwiler, P. Zúñiga, F. Bachnick, S. Gehri, B. de Jonghe, J. F. M. Hasemann, W. Eur Geriatr Med 2022

Aged
Cross-Sectional Studies
*Delirium/diagnosis/epidemiology
*Geriatric Assessment/methods
Humans
Nursing Homes
Pilot Projects
Prospective Studies
Delirium
Delirium assessment
Validation study

Association of preoperative frailty and postoperative delirium in older cancer patients undergoing elective abdominal surgery: a prospective observational study in Taiwan Tsai, C. Y. Liu, K. H. Lai, C. C. Hsu, J. T. Hsueh, S. W. Hung, C. Y. Yeh, K. Y. Hung, Y. S. Lin, Y. C. Chou, W. C. Biomed J 2022

cancer
delirium frailty.
surgery

Delirium and Cortical Complexity: Divergent Changes in Alpha and Theta Bands Tanabe, S. Parker, M. Lennertz, R. Pearce, R. A. Banks, M. I. Sanders, R. D. J Gerontol A Biol Sci Med Sci 2022
Escaping delirium: Designing an escape room active learning experience for geriatric resource nurses Stoller, A. Iannuzzo, S. Davis, K. Geriatr Nurs 2022

Creative problem solving
Critical thinking
Delirium
Escape rooms
Nursing workforce development

Perivascular spaces visible on magnetic resonance imaging predict subsequent delirium in older patients Song, Q. Zhao, Y. Lin, T. Yue, J. Front Aging Neurosci 2022

cerebral small vessel disease
delirium
magnetic resonance imaging
older people
perivascular spaces

Postoperative delirium does not affect cardiopulmonary exercise testing in aged patients undergoing cardiac valve surgery Shimomoto, Y. Mukaiyama, K. Hori, T. Inaki, Y. Masai, T. Hayashi, Y. JA Clin Rep 2022

Cardiac rehabilitation
Cardiopulmonary exercise testing
Heart surgery
Postoperative delirium

Silent cerebral ischemia detected by magnetic resonance imaging can predict postoperative delirium after total arch replacement for aneurysm Shibagaki, K. Shirasaka, T. Sawada, J. Saijo, Y. Kunioka, S. Kikuchi, Y. Kamiya, H. JTCVS Open 2022

AAA, aortic arch aneurysm
AR, arch replacement
CI, confidence interval
DSWMH, deep subcortical white matter hyperintensities
ICDSC, Intensive Care Delirium Screening Checklist
ICU, intensive care unit
MRI, magnetic resonance imaging
NCS, Neelon and Champagne confusion scale
NPD, nonpostoperative delirium
OR, odds ratio
PD, postoperative delirium
PVH, periventricular hyperintensity
SCP, selective cerebral perfusion
TAR, total arch replacement
TEVAR, thoracic endovascular aortic repair
WMH, white matter hyperintensity
magnetic resonance imaging
postoperative delirium
total arch replacement
white matter intensity

Impact of delirium on the outcome of stroke: a prospective, observational, cohort study Rollo, E. Brunetti, V. Scala, I. Callea, A. Marotta, J. Vollono, C. Frisullo, G. Broccolini, A. Calabresi, P. Della Marca, G. J Neurol 2022

Delirium
Disability
Mortality
Outcome
Prognosis
Stroke

Association between non-English language and use of physical and chemical restraints among medical inpatients with delirium Reppas-Rindlisbacher, C. Shin, S. Purohit, U. Verma, A. Razak, F. Rochon, P. Sheehan, K. Rawal, S. J Am Geriatr Soc 2022
Sedation, analgesia, and delirium management in Portugal: a survey and point prevalence study Paulino, M. C. Pereira, I. J. Costa, V. Neves, A. Santos, A. Teixeira, C. M. Coimbra, I. Fernandes, P. Bernardo, R. Póvoa, P. Granja, C. Rev Bras Ter Intensiva 2022

*Analgesia
Analgesics, Opioid
Cross-Sectional Studies
*Delirium/epidemiology
Humans
Hypnotics and Sedatives/therapeutic use
Intensive Care Units
Pain/drug therapy/epidemiology
Portugal/epidemiology
Prevalence

Acute kidney injury-associated delirium: a review of clinical and pathophysiological mechanisms Pang, H. Kumar, S. Ely, E. W. Gezalian, M. M. Lahiri, S. Crit Care 2022

*Acute Kidney Injury
Critical Illness
*Delirium
Humans
Risk Factors
*Water-Electrolyte Imbalance

Delirium Development After Lung Transplantation: An Intraoperative Assessment Ozay, H. Y. Bindal, M. Turkkan, S. Beyoglu, M. A. Yekeler, E. Turan, S. Transplant Proc 2022
Delirium severity does not differ between medical and surgical intensive care units after adjusting for medication use Ortiz, D. Lindroth, H. L. Braly, T. Perkins, A. J. Mohanty, S. Meagher, A. D. Khan, S. H. Boustani, M. A. Khan, B. A. Sci Rep 2022

Activities of Daily Living
Adolescent
Adult
Analgesics, Opioid/therapeutic use
Benzodiazepines/therapeutic use
Consciousness Disorders/complications
Critical Care
*Delirium/drug therapy/etiology
Female
Humans
Intensive Care Units
Male
Middle Aged

Risk factors for postoperative delirium on oxygen delivery-guided perfusion Mukaida, H. Matsushita, S. Minami, Y. Sato, G. Usuba, M. Kondo, R. Asai, T. Amano, A. J Cardiothorac Surg 2022

Cardiopulmonary Bypass/adverse effects/methods
*Delirium/etiology/prevention & control
Humans
Oxygen
Perfusion/adverse effects
*Postoperative Complications/etiology/prevention & control
Retrospective Studies
Risk Factors
Cardiopulmonary bypass
Goal directed perfusion
Hemodilution
Optimal perfusion
Oxygen delivery

Identifying Medicare Beneficiaries With Delirium Moura, Lmvr Zafar, S. Benson, N. M. Festa, N. Price, M. Donahue, M. A. Normand, S. L. Newhouse, J. P. Blacker, D. Hsu, J. Med Care 2022
The development of a web-based app employing machine learning for delirium prevention in long-term care facilities in South Korea Moon, K. J. Son, C. S. Lee, J. H. Park, M. BMC Med Inform Decis Mak 2022

*Delirium/diagnosis/prevention & control
Humans
Internet
Long-Term Care
Machine Learning
*Mobile Applications
Republic of Korea
Clinical decision support system
Delirium
Long-term care facility
Mobile apps
Rule-based prediction

Impact of Family Presence on Delirium in Critically Ill Patients: A Retrospective Cohort Study Mohsen, S. Moss, S. J. Lucini, F. Krewulak, K. D. Stelfox, H. T. Niven, D. J. Sauro, K. M. Fiest, K. M. Crit Care Med 2022
Serum levels of apolipoprotein A-I and E are associated with postoperative delirium: A post hoc analysis Mietani, K. Hasegawa-Moriyama, M. Inoue, R. Ogata, T. Shimojo, N. Kurano, M. Yatomi, Y. Uchida, K. Sumitani, M. Medicine (Baltimore) 2022

Aged
*Apolipoprotein A-I
Biomarkers
*Delirium/diagnosis/etiology/psychology
Humans
Postoperative Complications/diagnosis
Prospective Studies
Risk Factors

Staff training and the use of rapid, accurate and user-friendly tools for delirium screening could improve the diagnosis of delirium in the elderly referred to the emergency department Mazzola, P. Spedale, V. Evid Based Nurs 2022

evidence-based nursing
mental health
nursing
nursing research

Current practice of pharmacological treatment for hyperactive delirium in terminally ill cancer patients: results of a nationwide survey of Japanese palliative care physicians and liaison psychiatrists Matsuda, Y. Morita, T. Oya, K. Tagami, K. Naito, A. S. Kashiwagi, H. Otani, H. Jpn J Clin Oncol 2022

*Antipsychotic Agents/therapeutic use
Benzodiazepines/therapeutic use
*Delirium/drug therapy
Haloperidol/therapeutic use
Humans
Japan
*Neoplasms/complications/drug therapy
Palliative Care
*Physicians
*Psychiatry
Surveys and Questionnaires
Terminally Ill
antipsychotic
cancer
hyperactive delirium
pharmacological treatment
terminal delirium

Higher serum PGE2 is a predicative biomarker for postoperative delirium following elective orthopedic surgery in elderly patients Mao, M. Wang, L. Y. Zhu, L. Y. Wang, F. Ding, Y. Tong, J. H. Sun, J. Sun, Q. Ji, M. H. BMC Geriatr 2022

Aged
Biomarkers
*Delirium/diagnosis/epidemiology/etiology
Dinoprostone
Humans
*Orthopedic Procedures/adverse effects
Postoperative Complications/diagnosis/epidemiology/etiology
Prospective Studies
Risk Factors
Biomarker
Orthopedic surgery
Pge2
Postoperative delirium

Effect of acute pain on the association between preoperative cognitive impairment and postoperative delirium: a secondary analysis of three trials Ma, J. H. Liu, Y. F. Hong, H. Li, C. J. Cui, F. Mu, D. L. Wang, D. X. Br J Anaesth 2022

cognitive dysfunction
delirium
mediation analysis
postoperative complications
postoperative pain

A systematic review of modified electroconvulsive therapy (ECT) to treat delirium Lupke, K. Warren, N. Teodorczuk, A. Steele, S. Kolur, U. Wand, A. Robinson, G. Parker, S. Acta Psychiatr Scand 2022

acute confusion
delirium
electroconvulsive therapy
treatment

Incidence and interaction factors of delirium as an independent risk of mortality in elderly patients in the intensive units: a retrospective analysis from MIMIC-IV database Liu, H. Zhao, Q. Liu, X. Hu, X. Wang, L. Zhou, F. Aging Clin Exp Res 2022

Delirium
Elderly patients
Hemoglobin
Mortality
Sofa

The effect of neostigmine on postoperative delirium after colon carcinoma surgery: a randomized, double-blind, controlled trial Liu, F. Lin, X. Lin, Y. Deng, X. Guo, Y. Wang, B. Dong, R. Bi, Y. BMC Anesthesiol 2022

Adult
Aged
Aged, 80 and over
*Carcinoma
Colon
*Delirium/epidemiology/etiology/prevention & control
Double-Blind Method
Humans
Middle Aged
Neostigmine/therapeutic use
Postoperative Complications/epidemiology/prevention & control
Retrospective Studies
Colon carcinoma surgery
Neostigmine
Postoperative delirium
Postoperative pulmonary complications
Tof

Outcomes of postoperative delirium in patients undergoing cardiac surgery: A systematic review and meta-analysis Lin, L. Zhang, X. Xu, S. Peng, Y. Li, S. Huang, X. Chen, L. Lin, Y. Front Cardiovasc Med 2022

cardiac surgery
meta-analysis
mortality
outcome
postoperative delirium
systematic review

Non-pharmacological delirium prevention practices among critical care nurses: a qualitative study Liang, S. Chau, J. P. C. Lo, S. H. S. Zhao, J. Liu, W. BMC Nurs 2022

Delirium
Intensive care units
Non-pharmacological delirium prevention practice
Registered nurses

Effect of regional anesthesia on the postoperative delirium: A systematic review and meta-analysis of randomized controlled trials Li, T. Dong, T. Cui, Y. Meng, X. Dai, Z. Front Surg 2022

delirium
general anesthesia
meta—analysis
pain
regional anesthesia

Assessing Delirium at Hospital Discharge Lepkowsky, C. M. Janklow, H. M. Am J Geriatr Psychiatry 2022

Delirium
assessment
hospital discharge
older adults

The Effects of Pain, Agitation, Delirium, Immobility, and Sleep Disruption Education on Novice Nurses in Adult Intensive Care Units Lee, S. Y. Liu, C. Y. Wu, T. Y. Healthcare (Basel) 2022

Padis
adult intensive care unit
clinical ladder
education intervention
novice nurse

Treatment of Positive Urine Cultures at End-of-Life and the Effect on Terminal Delirium Management Latuga, N. M. Grant, P. C. Levy, K. Luczkiewicz, D. L. Am J Hosp Palliat Care 2022

Anti-Bacterial Agents/therapeutic use
Death
*Delirium/drug therapy
Humans
Palliative Care
Retrospective Studies
*Urinary Tract Infections/drug therapy
antibiotics
antimicrobial
delirium
end-of-life
hospice
infection
palliative
terminal

Risk factors and effect of postoperative delirium on adverse surgical outcomes in older adults after elective abdominal cancer surgery in Taiwan Lai, C. C. Liu, K. H. Tsai, C. Y. Hsu, J. T. Hsueh, S. W. Hung, C. Y. Chou, W. C. Asian J Surg 2022

Cancer surgery
Delirium
Elderly
Oncogeriatric patient
Taiwan

A Quality Improvement Study on Delirium Awareness Day: In Pursuit of Missed Delirium Diagnoses Koca, M. Öztürk, Y. Boğa, İ Bürkük, S. Eşme, M. Akyürek, Y. Şimşek, S. Aydın, D. D. Çiçek, F. Karabulut, E. Halil, M. Cankurtaran, M. Tanrıöver, M. D. Doğu, B. B. J Gerontol Nurs 2022

Aged
*Delirium/diagnosis/epidemiology
Humans
Mass Screening
Prospective Studies
Quality Improvement

Serum C-reactive protein adds predictive information for post-stroke delirium: The PROPOLIS study Klimiec-Moskal, E. Slowik, A. Dziedzic, T. Acta Psychiatr Scand 2022

Crp
delirium
prediction
stroke

External validation and comparison of two delirium prediction models in patients admitted to the cardiac intensive care unit Kim, S. E. Ko, R. E. Na, S. J. Chung, C. R. Choi, K. H. Kim, D. Park, T. K. Lee, J. M. Song, Y. B. Choi, J. O. Hahn, J. Y. Choi, S. H. Gwon, H. C. Yang, J. H. Front Cardiovasc Med 2022

Early PREdiction of DELIRium
PREdiction of DELIRium
cardiac intensive care unit
delirium prediction
prediction model

Delirium and Cortical Complexity Kim, H. Lee, U. C. Vlisides, P. E. Delirium and Cortical Complexity 2022
Can Variables From the Electronic Health Record Identify Delirium at Bedside? Khan, A. Heslin, K. Simpson, M. Malone, M. L. J Patient Cent Res Rev 2022

delirium
diagnosis
disease prediction model
electronic health record
ethnoracial

Thoracic Paravertebral Block Ameliorates Postoperative Delirium in Geriatric Patients Heng, L. Wang, M. Wang, M. Li, L. Zhu, S. Thorac Cardiovasc Surg 2022

Aged
*Delirium/diagnosis/etiology/prevention & control
Humans
Nausea
Pain, Postoperative/diagnosis/etiology/prevention & control
*Propofol/adverse effects
*Pulmonary Atelectasis
Remifentanil
Treatment Outcome
Vomiting

Relationship of sleep disturbance and postoperative delirium: a systematic review and meta-analysis He, E. Dong, Y. Jia, H. Yu, L. Gland Surg 2022

Postoperative delirium (PD)
meta-analysis
sleep disturbance
systematic review

Acceptability of transdermal antipsychotic patches by patients who refuse oral medication and their effectiveness in preventing recurrence of delirium: a retrospective observational study Hatta, K. Usui, C. Nakamura, H. Int Clin Psychopharmacol 2022
Perioperative Hemodynamic Optimization in Patients at Risk for Delirium - A Randomized-Controlled Trial Fuest, K. E. Servatius, A. Ulm, B. Schaller, S. J. Jungwirth, B. Blobner, M. Schmid, S. Front Med (Lausanne) 2022

frailty
goal-directed hemodynamic monitoring
goal-directed therapy
outcome
post-operative delirium

Proposing a Scientific and Technological Approach to the Summaries of Clinical Issues of Inpatient Elderly with Delirium: A Viewpoint Frisardi, V. Nicolini, M. Cautero, N. Ghirardelli, R. Davolio, F. Haouili, M. Barani, M. Healthcare (Basel) 2022

delirium
disease management
healthcare
patient care management
technology
telemedicine

Incidence of Drug-Induced Delirium During Treatment With Antidepressants or Antipsychotics: A Drug Surveillance Report of German-Speaking Countries Between 1993 and 2016 Friedrich, M. E. Grohmann, R. Rabl, U. Winkler, D. Konstantinidis, A. Engel, R. Seifert, J. Toto, S. Stübner, S. Frey, R. Kasper, S. Int J Neuropsychopharmacol 2022

Adverse Drug Reaction Reporting Systems
Amitriptyline
Antidepressive Agents/adverse effects
*Antipsychotic Agents/adverse effects
*Clozapine
*Delirium/chemically induced/drug therapy/epidemiology
Humans
Incidence
Muscarinic Antagonists
*Psychoses, Substance-Induced
Adverse drug reactions
antidepressants
antipsychotics
delirium
drug surveillance

The inter-relationship between delirium and dementia: the importance of delirium prevention Fong, T. G. Inouye, S. K. Nat Rev Neurol 2022
Five-Year Outcomes After Implementing a Pain, Agitation, and Delirium Protocol in a Mixed Intensive Care Unit Fish, J. T. Baxa, J. T. Draheim, R. R. Willenborg, M. J. Mills, J. C. Sticht, L. A. Hankwitz, J. L. Wells, J. A. Jung, H. S. J Intensive Care Med 2022

Adult
Analgesics/therapeutic use
*Delirium/drug therapy
Humans
Hypnotics and Sedatives/therapeutic use
Intensive Care Units
Length of Stay
Pain/drug therapy
Respiration, Artificial
Retrospective Studies
analgesics
cost analysis
costs
critical care
hypnotics and sedatives
protocol

Improving Delirium Assessments in Vanderbilt Pediatric and Pediatric Cardiovascular Intensive Care Units Eken, H. N. Betters, K. A. Fuchs, D. C. Smith, H. A. B. Williams, S. R. Pediatr Qual Saf 2022
Outcomes in Post-operative Delirium Following Bowel Resection: A Single Center Retrospective Review Desrochers, R. M. Lynch, L. J. Gates, J. D. Ricaurte, D. Wade, J. T. Dicks, R. S. Keating, J. J. J Surg Res 2022

Bowel
Delirium
Elective
Emergency
Mortality
Resection

Efficacy and Safety of Remimazolam Besylate versus Dexmedetomidine for Sedation in Non-Intubated Older Patients with Agitated Delirium After Orthopedic Surgery: A Randomized Controlled Trial Deng, Y. Qin, Z. Wu, Q. Liu, L. Yang, X. Ju, X. Zhang, Y. Liu, L. Drug Des Devel Ther 2022

Benzodiazepines
*Delirium/drug therapy
*Dexmedetomidine/adverse effects
Humans
Hypnotics and Sedatives/adverse effects
*Orthopedic Procedures
agitation
delirium
dexmedetomidine
older adult
orthopedics
remimazolam besylate

Delirium, changes in cognitive function, and risk of diagnosed dementia after kidney transplantation Chu, N. M. Bae, S. Chen, X. Ruck, J. Gross, A. L. Albert, M. Neufeld, K. J. Segev, D. L. McAdams-DeMarco, M. A. Am J Transplant 2022

clinical research/practice
cognitive function
delirium
epidemiology
health services and outcomes research
kidney disease
kidney transplant
kidney transplantation/nephrology
mental health
neurology

Bispectral Index (BIS) Monitoring and Postoperative Delirium in Elderly Patients Undergoing Surgery: A Systematic Review and Meta-Analysis With Trial Sequential Analysis Chew, W. Z. Teoh, W. Y. Sivanesan, N. Loh, P. S. Shariffuddin,, II Ti, L. K. Ng, K. T. J Cardiothorac Vasc Anesth 2022

Bis
elderly
meta-analysis
postoperative cognitive dysfunction
postoperative delirium
systematic review

Delirium prevalence in geriatric emergency department patients: A systematic review and meta-analysis Chen, F. Liu, L. Wang, Y. Liu, Y. Fan, L. Chi, J. Am J Emerg Med 2022

Aged
*Delirium/diagnosis/epidemiology
Emergency Service, Hospital
Humans
Mass Screening
Prevalence
Delirium
Meta-analysis
Older adults

Improving quantification of anticholinergic burden using the Anticholinergic Effect on Cognition Scale - a healthcare improvement study in a geriatric ward setting Balasundaram, B. Ang, W. S. T. Stewart, R. Bishara, D. Ooi, C. H. Li, F. Akram, F. Eu Kwek, A. B. Australas Psychiatry 2022

Aged
*Cholinergic Antagonists/adverse effects
Cognition
*Cognition Disorders
Delivery of Health Care
Hospitals
Humans
anticholinergic burden scales
anticholinergic drugs
anticholinergic effect on cognition scale
delirium
dementia

The Association of Selective Serotonin Reuptake Inhibitors With Delirium in Critically Ill Adults: A Secondary Analysis of the Bringing to Light the Risk Factors and Incidence of Neuropsychologic Dysfunction in ICU Survivors ICU Study Austin, C. A. Yi, J. Lin, F. C. Pandharipande, P. Ely, E. W. Busby-Whitehead, J. Carson, S. S. Crit Care Explor 2022

delirium
intensive care unit outcomes
neurophysiology
neurotransmitters
selective serotonin reuptake inhibitors
interest.

Parental Education and Delirium Risk after Surgery in Older Adults Arias, F. Chen, F. Shiff, H. Marcantonio, E. R. Jones, R. N. Schmitt, E. M. Metzger, E. Fong, T. G. Travison, T. G. Inouye, S. K. Clin Gerontol 2022

Childhood socioeconomic status
delirium
social determinants of health

Informing the standardising of care for prolonged stay patients in the ICU: A scoping review of quality improvement tools Allum, L. Apps, C. Pattison, N. Connolly, B. Rose, L. Intensive Crit Care Nurs 2022

Bundle
Care standardisation
Checklist
Critical care
Persistent or chronic critical illness
Quality improvement

Monitoring of nighttime EEG slow-wave activity during dexmedetomidine infusion in patients with hyperactive ICU delirium: An observational pilot study Ala-Kokko, T. Erikson, K. Koskenkari, J. Laurila, J. Kortelainen, J. Acta Anaesthesiol Scand 2022

C-trend
Rcsq
sleep

Development of a Delirium Risk Predication Model among ICU Patients in Oman Al-Hoodar, R. K. Lazarus, E. R. Alomari, O. Alzaabi, O. Anesthesiol Res Pract 2022
Comparison Between Deltascan Single Channel Electroencephalography (EEG), Confusion Assessment Method-Intensive Care Unit (CAM-ICU) Score and Clinical Assessment in Diagnosing Delirium in Intubated Patients in the Intensive Care Unit Aben, J. Pouwels, S. Oldenbeuving, A. Cureus 2022

cam-icu
complications
delirium
electroencephalography
intensive care
monitoring

A Cross-Sectional Survey on the Clinical Management of Emergence Delirium in Adults: Knowledge, Attitudes, and Practice in Mainland China Yuan, Y. Lei, B. Li, Z. Wang, X. Zhao, H. Gao, M. Xue, Y. Zhang, W. Xiao, R. Meng, X. Zheng, H. Zhang, J. Wang, G. Guo, X. Brain Sci 2022

Pacu
anesthesia nurse
emergence delirium

Development and Validation of a Nomogram for Predicting Postoperative Delirium in Patients With Elderly Hip Fracture Based on Data Collected on Admission Yang, Y. Wang, T. Guo, H. Sun, Y. Cao, J. Xu, P. Cai, Y. Front Aging Neurosci 2022

albumin
chronic obstructive pulmonary disease
dementia
elderly hip fracture
nomogram
postoperative delirium
prediction model

Preoperative Inflammatory Markers and the Risk of Postoperative Delirium in Patients Undergoing Lumbar Spinal Fusion Surgery Yang, J. S. Lee, J. J. Kwon, Y. S. Kim, J. H. Sohn, J. H. J Clin Med 2022

CRP-to-albumin ratio
monocyte-to-lymphocyte ratio
neutrophil-to-lymphocyte ratio
postoperative delirium
spine surgery

An association between cancer type and delirium incidence in Japanese elderly patients: A retrospective longitudinal study Yamato, K. Ikeda, A. Endo, M. Filomeno, R. Kiyohara, K. Inada, K. Nishimura, K. Tanigawa, T. Cancer Med 2022

cancer
delirium
longitudinal study

Increased Direct Current-Electroencephalography Shifts During Induction of Anesthesia in Elderly Patients Developing Postoperative Delirium Windmann, V. Dreier, J. P. Major, S. Spies, C. Lachmann, G. Koch, S. Front Aging Neurosci 2022

*dc-eeg
*anesthesia induction
*blood–brain barrier
*direct current EEG
*electroencephalography
*hyperventilation
*postoperative delirium (POD)

Risk factors of delirium after gastrointestinal surgery: A meta-analysis Wang, X. Yu, D. Du, Y. Geng, J. J Clin Nurs 2022

delirium
gastrointestinal
risk factor

Physician Experience Design (PXD): More Usable Machine Learning Prediction for Clinical Decision Making Wang, L. Chignell, M. Zhang, Y. Pinto, A. Razak, F. Sheehan, K. Verma, A. AMIA Annu Symp Proc 2022

Artificial Intelligence
Clinical Decision-Making
Decision Making
*Delirium
Humans
Machine Learning
*Physicians/psychology

The Relationship Between Cardiovascular Disease Risk Score and Postoperative Delirium: The PNDABLE Study Wang, J. Wang, L. Tang, X. Wang, F. Liu, S. Wu, X. Dong, R. Lin, X. Wang, B. Bi, Y. Front Aging Neurosci 2022

biomarkers
cerebrospinal fluid
mediation analysis
postoperative delirium
vascular risk score
commercial or financial relationships that could be construed as a potential
conflict of interest.

Preoperative intervention to prevent delirium in patients with hip fracture - a systematic review Virsøe-Frandsen, C. D. Skjold, C. Wildgaard, K. Møller, A. M. Dan Med J 2022

Aged
*Delirium/etiology/prevention & control
Geriatric Assessment
*Hip Fractures/surgery
Humans
Odds Ratio
Preoperative Care

Coexisting delirium and excited catatonia Vellanki, K. D. Carroll, B. T. Ann Clin Psychiatry 2022

*Antipsychotic Agents/therapeutic use
*Catatonia
*Delirium/drug therapy
Humans

Confusion regarding the use of Natural Language Processing in ICU delirium assessment van Diem-Zaal, I. J. van den Boogaard, M. Kotfis, K. Ely, E. W. Intensive Care Med 2022

*Delirium/diagnosis
Humans
Intensive Care Units
*Natural Language Processing
Reproducibility of Results

Postoperative delirium and changes in the blood-brain barrier, neuroinflammation, and cerebrospinal fluid lactate: a prospective cohort study Taylor, J. Parker, M. Casey, C. P. Tanabe, S. Kunkel, D. Rivera, C. Zetterberg, H. Blennow, K. Pearce, R. A. Lennertz, R. C. Sanders, R. D. Br J Anaesth 2022

Biomarkers
*Blood-Brain Barrier
*Delirium/diagnosis
Humans
Interleukin-6
Lactic Acid
Neuroinflammatory Diseases
Prospective Studies
S100 Calcium Binding Protein beta Subunit/cerebrospinal fluid
*delirium
*dementia
*inflammation
*neuronal injury
*older adults
*surgery

Prospective clinical intervention study of aripiprazole and risperidone in the management of postoperative delirium in elderly patients after cardiovascular surgery Sugawara, H. Koyama, A. Maruyama, T. Koda, Y. Fukunaga, H. Ishikawa, T. Takebayashi, M. Okamoto, K. Fukui, T. Hashimoto, M. Psychiatry Clin Neurosci 2022
A simple risk score list can be used to predict the occurrence of delirium in patients admitted to inpatient hospice care: A medical record study Stoevelaar, R. Juffermans, C. C. M. Roorda, I. M. M. de Nijs, E. J. M. Hoornweg, J. Cannegieter, S. C. van der Linden, Y. M. Eur J Cancer Care (Engl) 2022

delirium
end-of-life care
hospice and palliative care nursing
hospice care
retrospective studies
terminal care

Chemokines in ICU Delirium: An Exploratory Study Smith, R. J. Rabinstein, A. A. Cartin-Ceba, R. Singh, V. P. Lachner, C. Khatua, B. Trivedi, S. Gajic, O. Crit Care Explor 2022

chemokine
cytokine
delirium
inflammation
intensive care unit
interest.

Cytokine profiles in intensive care unit delirium Smith, R. J. Lachner, C. Singh, V. P. Trivedi, S. Khatua, B. Cartin-Ceba, R. Acute Crit Care 2022

cytokine
delirium
encephalopathy
intensive care unit
neuroinflammation

Edmonton frailty scale score predicts postoperative delirium: a retrospective cohort analysis Sieber, F. Gearhart, S. Bettick, D. Wang, N. Y BMC Geriatr 2022

Cohort Studies
*Delirium/diagnosis/epidemiology/etiology
*Frailty/complications/diagnosis
Humans
Postoperative Complications/diagnosis/epidemiology/etiology
Prospective Studies
Retrospective Studies
Risk Factors
*Complications
*Delirium
*Elective surgical procedures
*Frailty
*Postoperative

Observation of Anesthetic Effect of Dexmedetomidine Combined With Intraspinal Anesthesia in Hip Arthroplasty and its Effect on Postoperative Delirium and Stress Response Shen, Y. Wang, C. Zhong, X. Wu, Y. He, X. Front Surg 2022

anesthetic effects
delirium
dexmedetomidine
hip replacement
immunologic function
intraspinal anesthesia
stress response
commercial or financial relationships that could be construed as a potential
conflict of interest.

Postoperative Application of Dexmedetomidine is the Optimal Strategy to Reduce the Incidence of Postoperative Delirium After Cardiac Surgery: A Network Meta-Analysis of Randomized Controlled Trials Shang, L. Hou, M. Guo, F. Ann Pharmacother 2022

cardiac surgery
cognitive dysfunction
dexmedetomidine
network meta-analysis
postoperative delirium

Decreasing delirium through music listening (DDM) in critically ill, mechanically ventilated older adults in the intensive care unit: a two-arm, parallel-group, randomized clinical trial Seyffert, S. Moiz, S. Coghlan, M. Balozian, P. Nasser, J. Rached, E. A. Jamil, Y. Naqvi, K. Rawlings, L. Perkins, A. J. Gao, S. Hunter, J. D., 3rd Khan, S. Heiderscheit, A. Chlan, L. L. Khan, B. Trials 2022

Aged
Critical Illness/psychology
*Delirium/diagnosis/prevention & control
Humans
Intensive Care Units
*Music
Pain
Respiration, Artificial/adverse effects
Acute respiratory failure
Anxiety
Cognition
Delirium
Intensive care unit
Mechanical ventilation
Music
Post-intensive care syndrome

Prevention of delirium with agitation by yokukansan in older adults after cancer surgery Sadahiro, R. Wada, S. Matsuoka, Y. J. Uchitomi, Y. Yamaguchi, T. Sato, T. Esaki, M. Yoshimoto, S. Daiko, H. Kanemitsu, Y. Kawai, A. Kato, T. Fujimoto, H. Uezono, Y. Shimizu, K. Matsuoka, H. Jpn J Clin Oncol 2022

clinical trial
gerontology
psycho-oncology
surgical oncology

Midazolam impacts acetyl-And butyrylcholinesterase genes: An epigenetic explanation for postoperative delirium? Rump, K. Holtkamp, C. Bergmann, L. Nowak, H. Unterberg, M. Orlowski, J. Thon, P. Bazzi, Z. Bazzi, M. Adamzik, M. Koos, B. Rahmel, T. PLoS One 2022

Acetylcholinesterase/metabolism
Butyrylcholinesterase
Cholinesterase Inhibitors/pharmacology
*Delirium/etiology
Epigenesis, Genetic
Histone Demethylases/metabolism
Histones/metabolism
Humans
Leukocytes, Mononuclear/metabolism
Lysine/metabolism
Midazolam/pharmacology
*Neuroblastoma/genetics

Ren, X. Zhang, S. Yang, Y. Song, A. Liang, F. Zhang, Y. Dong, Y. Wu, X. Xie, Z. Ketamine Induces Delirium-Like Behavior and Interferes With Endosomal Tau Trafficking Anesth Analg 2022
The crucial factors influencing the development and outcomes of postoperative delirium in proximal femur fractures Rajeev, A. Railton, C. Devalia, K. Aging Med (Milton) 2022

delirium
development
outcomes
postoperative
proximal femur fractures

Neuromonitoring depth of anesthesia and its association with postoperative delirium Pérez-Otal, B. Aragón-Benedí, C. Pascual-Bellosta, A. Ortega-Lucea, S. Martínez-Ubieto, J. Ramírez-Rodríguez, J. M. Sci Rep 2022

Anesthesia, General/adverse effects
*Anesthesiology
*Anesthetics
*Delirium/etiology/prevention & control
Humans
Postoperative Complications/epidemiology/etiology/prevention & control

Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): protocol for a co-design and feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care Pearson, M. Jackson, G. Jackson, C. Boland, J. Featherstone, I. Huang, C. Ogden, M. Sartain, K. Siddiqi, N. Twiddy, M. Johnson, M. BMJ Open 2022

*Delirium/diagnosis/prevention & control
Delivery of Health Care
Feasibility Studies
*Hospices
Humans
Wales
*delirium & cognitive disorders
*palliative care
*protocols & guidelines

An Interdisciplinary Reappraisal of Delirium and Proposed Subtypes Oldham, M. A. Slooter, A. J. C. Ely, E. W. Crone, C. Maldonado, J. R. Rosenthal, L. J. J Acad Consult Liaison Psychiatry 2022

acute encephalopathy
altered mental status
delirium disorder
neuropsychiatric symptoms
pathophysiology
subtypes

Postoperative Delirium in Patients with Oral Cancer: Is Intraoperative Fluid Administration a Neglected Risk Factor? Obermeier, K. T. Kraus, M. Smolka, W. Henkel, J. Saller, T. Otto, S. Liokatis, P. Cancers (Basel) 2022

fluid balance
fluid management
head and neck surgery
oral cancer
postoperative delirium

Risk of delirium associated with antimuscarinics in older adults: A case-time-control study Nishtala, P. S. Chyou, T. Y. Pharmacoepidemiol Drug Saf 2022

Aged
Aged, 80 and over
Cholinergic Antagonists
*Delirium/chemically induced/drug therapy/epidemiology
Humans
Muscarinic Antagonists/adverse effects
Solifenacin Succinate/adverse effects
*Urinary Bladder, Overactive/chemically induced
*adverse effects
*antimuscarinics
*delirium
*elderly
*pharmacoepidemiology