What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Preventing Postoperative Delirium After Major Noncardiac Thoracic Surgery-A Randomized Clinical Trial.
- Authors
- Khan, B. A. Perkins, A. J. Campbell, N. L. Gao, S. Khan, S. H. Wang, S. Fuchita, M. Weber, D. J. Zarzaur, B. L. Boustani, M. A. Kesler, K.
- Year
- 2018
- Journal
- J Am Geriatr Soc
- Abstract
OBJECTIVES: To assess the efficacy of haloperidol in reducing postoperative delirium in individuals undergoing thoracic surgery. DESIGN: Randomized double-blind placebo-controlled trial. SETTING: Surgical intensive care unit (ICU) of tertiary care center. PARTICIPANTS: Individuals undergoing thoracic surgery (N=135). INTERVENTION: Low-dose intravenous haloperidol (0.5 mg three times daily for a total of 11 doses) administered postoperatively. MEASUREMENTS: The primary outcome was delirium incidence during hospitalization. Secondary outcomes were time to delirium, delirium duration, delirium severity, and ICU and hospital length of stay. Delirium was assessed using the Confusion Assessment Method for the ICU and delirium severity using the Delirium Rating Scale-Revised. RESULTS: Sixty-eight participants were randomized to receive haloperidol and 67 placebo. No significant differences were observed between those receiving haloperidol and those receiving placebo in incident delirium (n=15 (22.1%) vs n=19 (28.4%); p = .43), time to delirium (p = .43), delirium duration (median 1 day, interquartile range (IQR) 1-2 days vs median 1 day, IQR 1-2 days; p = .71), delirium severity, ICU length of stay (median 2.2 days, IQR 1-3.3 days vs median 2.3 days, IQR 1-4 days; p = .29), or hospital length of stay (median 10 days, IQR 8-11.5 days vs median 10 days, IQR 8-12 days; p = .41). In the esophagectomy subgroup (n = 84), the haloperidol group was less likely to experience incident delirium (n=10 (23.8%) vs n=17 (40.5%); p = .16). There were no differences in time to delirium (p = .14), delirium duration (median 1 day, IQR 1-2 days vs median 1 day, IQR 1-2 days; p = .71), delirium severity, or hospital length of stay (median 11 days, IQR 10-12 days vs median days 11, IQR 10-15 days; p = .26). ICU length of stay was significantly shorter in the haloperidol group (median 2.8 days, IQR 1.1-3.8 days vs median 3.1 days, IQR 2.1-5.1 days; p = .03). Safety events were comparable between the groups. CONCLUSION: Low-dose postoperative haloperidol did not reduce delirium in individuals undergoing thoracic surgery but may be efficacious in those undergoing esophagectomy. J Am Geriatr Soc 66:2289-2297, 2018.
- PMID
- Keywords
Icu
cognition
delirium
esophagectomy
haloperidol
- Page(s)
- 2289-97
- Volume
- 66
- Issue
- 12
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Instruments to measure postintensive care syndrome: a scoping review protocol | Chu, Y. Timmins, F. Thompson, D. Eustace-Cook, J. | BMJ Open | 2022 |
Adult |
| Leucine-rich glioma-inactivated 1 antibody encephalitis as a rare cause of delirium | Ching, E. Murdoch, H. Mohammed, H. | Geriatr Gerontol Int | 2022 | |
| A novel semiautomatic Chinese keywords instrument screening delirium based on electronic medical records | Chen, L. Li, N. Zheng, Y. Gao, L. Ge, N. Xie, D. Yue, J. | BMC Geriatr | 2022 |
Aged |
| Effect of Preoperative Oral Saline Administration on Postoperative Delirium in Older Persons: A Randomized Controlled Trial | Chen, J. Xie, S. Chen, Y. Qiu, T. Lin, J. | Clin Interv Aging | 2022 |
Humans |
| Frailty and delirium in hospitalized older adults: A systematic review with meta-analysis | Cechinel, C. Lenardt, M. H. Rodrigues, J. A. M. Binotto, M. A. Aristides, M. M. Kraus, R. | Rev Lat Am Enfermagem | 2022 |
Humans |
| QEEG abnormalities in cognitively unimpaired patients with delirium | Carrarini, C. Calisi, D. De Rosa, M. A. Di Iorio, A. D'Ardes, D. Pellegrino, R. Gazzina, S. Pilotto, A. Arighi, A. Carandini, T. Cagnin, A. Mozzetta, S. Gallucci, M. Bonifati, D. M. Costa, C. D'Antonio, F. Bruno, G. Cipollone, F. Babiloni, C. Padovani, A. | J Neurol Neurosurg Psychiatry | 2022 |
Cognition |
| Prediction models for postoperative delirium after cardiac surgery: Systematic review and critical appraisal | Cai, S. Li, J. Gao, J. Pan, W. Zhang, Y. | Int J Nurs Stud | 2022 |
Cardiac surgery |
| Implementing a Delirium Risk Stratification Tool and Rounds to Identify and Prevent Delirium in Hospitalized Older Adults | Byrnes, T. Woodward, J. | J Nurs Care Qual | 2022 | |
| The Assessment of Immediate Postoperative Delirium in Neurologically Intact Adult Patients Admitted to the Post-anesthesia Care Unit: A Cross-Sectional Study | Burad, J. Date, R. Al Ismaili, M. Sharma, P. Kuriakose, N. Kodange, S. Birur, S. K. Al Yaqoubi, K. Al Mawali, A. Padmalayan, A. El Mady, H. Elawdy, M. Jaju, S. Al Abady, A. | Cureus | 2022 |
anesthesia recovery period |
| Deconstructing delirium in the post anaesthesia care unit | Banerji, A. Sleigh, J. W. Voss, L. J. Garcia, P. S. Gaskell, A. L. | Front Aging Neurosci | 2022 |
3d-cam |
| Association between remimazolam and postoperative delirium in older adults undergoing elective cardiovascular surgery: a prospective cohort study | Aoki, Y. Kurita, T. Nakajima, M. Imai, R. Suzuki, Y. Makino, H. Kinoshita, H. Doi, M. Nakajima, Y. | J Anesth | 2022 |
Cardiovascular surgical procedures |
| Haloperidol for the Treatment of Delirium in ICU Patients | Andersen-Ranberg, N. C. Poulsen, L. M. Perner, A. Wetterslev, J. Estrup, S. Hästbacka, J. Morgan, M. Citerio, G. Caballero, J. Lange, T. Kjær, M. N. Ebdrup, B. H. Engstrøm, J. Olsen, M. H. Oxenbøll Collet, M. Mortensen, C. B. Weber, S. O. Andreasen, A | N Engl J Med | 2022 | |
| Needs assessment survey of healthcare providers' perceptions and practices regarding delirium prevention at a university medical center | Alghamdi, B. Koroukian, S. M. Kresevic, D. Drummond, C. K. | Front Aging | 2022 |
assessment |
| Incidence, Associated Factors, and Outcome of Delirium among Patients Admitted to ICUs in Oman | Al-Hoodar, R. K. Lazarus, E. R. Al Omari, O. Al Zaabi, O. | Crit Care Res Pract | 2022 | |
| Dose-dependent relationship between intra-procedural hypoxaemia or hypocapnia and postoperative delirium in older patients | Ahrens, E. Tartler, T. M. Suleiman, A. Wachtendorf, L. J. Ma, H. Chen, G. Kendale, S. M. Kienbaum, P. Subramaniam, B. Wagner, S. Schaefer, M. S. | Br J Anaesth | 2022 |
haemodynamics |
| The Preventive Effect of Dexmedetomidine Against Delirium in Patients with Aortic Dissection: A Retrospective Cohort Study | Zhang, S. Yin, Q. Wang, Y. Yu, K. Shen, P. | Heart Surg Forum | 2022 |
*Aneurysm, Dissecting/complications/surgery |
| Prediction model for delirium in patients with cardiovascular surgery: development and validation | Xu, Y. Meng, Y. Qian, X. Wu, H. Liu, Y. Ji, P. Chen, H. | J Cardiothorac Surg | 2022 |
Calibration |
| Knowledge, attitudes and practices of ICU nurses regarding subsyndromal delirium among 20 hospitals in China: a descriptive cross-sectional survey | Xing, H. Zhu, S. Liu, S. Xia, M. Jing, M. Dong, G. Ni, W. Li, L. | BMJ Open | 2022 |
Attitude of Health Personnel |
| The prevention of delirium in elderly surgical patients with obstructive sleep apnea (PODESA): a randomized controlled trial | Wong, J. Doherty, H. R. Singh, M. Choi, S. Siddiqui, N. Lam, D. Liyanage, N. Tomlinson, G. Chung, F. | BMC Anesthesiol | 2022 |
Acetaminophen |
| Feasibility and potential of a bedside mini-EEG for diagnosing delirium superimposed on dementia | Wijnen, V. J. M. Oudewortel, L. van Luijtelaar, G. Witlox, J. Slooter, A. J. C. van Gool, W. A. | Clin Neurophysiol | 2022 |
Benzodiazepines |
| Recipe for primary prevention of delirium in hospitalized older patients | Vreeswijk, R. Maier, A. B. Kalisvaart, K. J. | Aging Clin Exp Res | 2022 |
Delirium |
| Demographic and clinical characteristics of patients with delirium: analysis of a nationwide Japanese medical database | Ueda, N. Igarashi, M. Okuyama, K. Sano, H. Takahashi, K. P. Qureshi Z Tokita, S. Ogawa, A. Okumura, Y. Okuda, S. | BMJ Open | 2022 |
Aged |
| Pharmacologic Management of Delirium in the Intensive Care Unit | Tiberio, P. J. Prendergast, N. T. Girard, T. D. | Clin Chest Med | 2022 |
*Delirium/drug therapy/etiology |
| Prevalence of Emergence Delirium and Associated Factors among Older Patients Who Underwent Elective Surgery: A Multicenter Observational Study | Tesfaye Mekonin, G. Kelbesa Olika, M. Birhanu Wedajo, M. Tolasa Badada, A. Dukessa Dubiwak, A. Tageza Ilala, T. Gebre, M. N. | Anesthesiol Res Pract | 2022 | |
| Impact of combined epidural anaesthesia/analgesia on postoperative cognitive impairment in patients receiving general anaesthesia: a meta-analysis of randomised controlled studies | Teng, I. C. Sun, C. K. Ho, C. N. Wang, L. K. Lin, Y. T. Chang, Y. J. Chen, J. Y. Chu, C. C. Hsing, C. H. Hung, K. C. | Anaesth Crit Care Pain Med | 2022 |
Adult |
| Computerized tool and interdisciplinary care for older patients with delirium in the emergency department: a novel model in Taiwan | Tan, T. H. Yang, T. Y. Chen, Y. M. Chung, S. Y. Liu, H. H. Yang, P. C. Kao, P. H. Peng, A. C. Shu, Y. M. Chu, Y. S. Tsai, K. T. Hsu, C. C. Ho, C. H. Lin, H. J. Huang, C. C. | Aging Clin Exp Res | 2022 |
Computerized |
| Use of Valproic Acid for the Management of Delirium and Agitation in the Intensive Care Unit | Swayngim, R. Preslaski, C. Dawson, J. | J Pharm Pract | 2022 |
agitation |
| Risk Factors for Acute Postoperative Delirium in Cardiac Surgery Patients >65 Years Old | Spiropoulou, E. Samanidis, G. Kanakis, M. Nenekidis, I. | J Pers Med | 2022 |
acute delirium |
| Systemic immune-inflammation index predicts postoperative delirium in elderly patients after surgery: a retrospective cohort study | Song, Y. Luo, Y. Zhang, F. Ma, Y. Lou, J. Li, H. Liu, Y. Mi, W. Cao, J. | BMC Geriatr | 2022 |
Aged |
| The influence of orthopedic surgery on the incidence of post-operative delirium in geriatric patients: results of a prospective observational study | Sircar, K. Yagdiran, A. Bredow, J. Annecke, T. Eysel, P. Scheyerer, M. J. | J Clin Orthop Trauma | 2022 |
Arthroplasty |
| Paternal Occupation and Delirium Risk in Older Adults: A Potential Marker of Early-Life Exposures | Shiff, H. M. Arias, F. Dufour, A. B. Carr, D. Chen, F. Gou, Y. Jones, R. Schmitt, E. Travison, T. G. Kunicki, Z. J. Okereke, O. I. Inouye, S. K. | Innov Aging | 2022 |
Cognitive reserve |
| Flurbiprofen used in one-lung ventilation improves intraoperative regional cerebral oxygen saturation and reduces the incidence of postoperative delirium | Shen, L. Chen, J. Q. Yang, X. L. Hu, J. C. Gao, W. Chai, X. Q. Wang, D. | Front Psychiatry | 2022 |
flurbiprofen |
| Derivation and validation of a prediction score for postoperative delirium in geriatric patients undergoing hip fracture surgery or hip arthroplasty | Shen, J. An, Y. Jiang, B. Zhang, P. | Front Surg | 2022 |
arthroplasty |
| Cognitive decline and dementia: does delirium matter? | Selbæk, G. Neerland, B. E. | Lancet Healthy Longev | 2022 |
*Cognitive Dysfunction |
| Understanding why delirium is often missed in older emergency department patients: a qualitative descriptive study | Schonnop, R. Dainty, K. N. McLeod, S. L. Melady, D. Lee, J. S. | Cjem | 2022 |
Acute care |
| Association between post-operative delirium and use of volatile anesthetics in the elderly: A real-world big data approach | Saller, T. Hubig, L. Seibold, H. Schroeder, Z. Wang, B. Groene, P. Perneczky, R. von Dossow, V. Hinske, L. C. | J Clin Anesth | 2022 |
Aged [D000368] |
| Risk Factors for Postoperative Delirium Identified | Rosenberg, K. | Am J Nurs | 2022 |
*Delirium/etiology |
| Delirium-associated medication in people at risk. A systematic update review, meta-analyses and GRADE-profiles | Reisinger, M. Reininghaus, E. Z. De Biasi, J. Fellendorf, F. T. Schoberer, D. | Acta Psychiatr Scand | 2022 |
Statements |
| The Predictive Role of Inflammatory Biochemical Markers in Post-Operative Delirium After Vascular Surgery Procedures | Pasqui, E. de Donato, G. Brancaccio, B. Casilli, G. Ferrante, G. Cappelli, A. Palasciano, G. | Vasc Health Risk Manag | 2022 |
Aged |
| Potential Usefulness of Blood Urea Nitrogen to Creatinine Ratio in the Prediction and Early Detection of Delirium Motor Subtype in the Intensive Care Unit | Park, W. R. Kim, H. R. Park, J. Y. Kim, H. E. Cho, J. Oh, J. | J Clin Med | 2022 |
biomarker |
| Perioperative Gabapentin Use and In-Hospital Adverse Clinical Events Among Older Adults After Major Surgery | Park, C. M. Inouye, S. K. Marcantonio, E. R. Metzger, E. Bateman, B. T. Lie, J. J. Lee, S. B. Levin, R. Kim, D. H. | JAMA Intern Med | 2022 | |
| Follow the Money: The Widening Coding Disparity Between Acute Encephalopathy and Delirium | Oldham, M. A. | J Acad Consult Liaison Psychiatry | 2022 |
*Brain Diseases |
| Use of Automated Infrared Pupillometry to Predict Delirium in the Intensive Care Unit: A Prospective Observational Study | Okamoto, S. Ishizawa, M. Inoue, S. Sakuramoto, H. | SAGE Open Nurs | 2022 |
automated infrared pupillometry |
| The Role of High Sensitivity C-reactive Protein to Predict Delirium Persistence in Elderly Patients with Pneumonia: A Prospective Cohort Study | Mulyana, R. Syafrita, Y. Ali, H. Murni, A. W. | Acta Med Indones | 2022 |
Aged |
| Peripheral interleukin-6-associated microglial QUIN elevation in basolateral amygdala contributed to cognitive dysfunction in a mouse model of postoperative delirium | Mu, J. L. Liu, X. D. Dong, Y. H. Fang, Y. Y. Qiu, S. D. Zhang, F. Liu, K. X. | Front Med (Lausanne) | 2022 |
Bla |
| The effect of taurine supplementation on delirium post liver transplantation: A randomized controlled trial | Mottaghi, S. Nikoupour, H. Firoozifar, M. Jalali, S. S. Jamshidzadeh, A. Vazin, A. Shafiekhani, M. | Clin Nutr | 2022 |
Delirium |
| The association of depression and postoperative delirium: we may need more information | Mestres, C. A. Quintana, E. | Interact Cardiovasc Thorac Surg | 2022 |
*Cardiac Surgical Procedures |
| Is mood associated with perception of recovery? Preoperative depression versus postoperative delirium after cardiac surgery | Mennander, A. A. | Interact Cardiovasc Thorac Surg | 2022 |
*Cardiac Surgical Procedures/adverse effects |
| An Automated Algorithm for Determining Sleep Using Single-Channel Electroencephalography to Detect Delirium: A Prospective Observational Study in Intensive Care Units | Matsui, K. Sato, N. Idei, M. Arakida, M. Seino, Y. Ishikawa, J. Y. Nakagawa, M. Akaho, R. Nishimura, K. Nomura, T. | Healthcare (Basel) | 2022 |
critically ill patients |
| Drug Choice for Hyperactive Delirium in Terminally-Ill Cancer Patients: A Nationwide Survey | Matsuda, Y. Morita, T. Oya, K. Tagami, K. Naito, A. S. Kashiwagi, H. Otani, H. | J Pain Symptom Manage | 2022 |
*Delirium/drug therapy |
| Dexmedetomidine potential in attenuating postoperative delirium in elderly patients after total hip joint replacement | Lv, Y. Gu, L. | Rev Assoc Med Bras (1992) | 2022 | |
| Challenges in detecting and managing mild cognitive impairment in primary care: a focus group study in Shanghai, China | Lu, Y. Liu, C. Wells, Y. Yu, D. | BMJ Open | 2022 |
Caregivers/psychology |
| The Age-adjusted Charlson Comorbidity Index predicts post-operative delirium in the elderly following thoracic and abdominal surgery: A prospective observational cohort study | Liu, J. Li, J. He, J. Zhang, H. Liu, M. Rong, J. | Front Aging Neurosci | 2022 |
Age-adjusted Charlson Comorbidity Index |
| Early alteration of peripheral blood lymphocyte subsets as a risk factor for delirium in critically ill patients after cardiac surgery: A prospective observational study | Li, X. Cheng, W. Zhang, J. Li, D. Wang, F. Cui, N. | Front Aging Neurosci | 2022 |
CD4+ T cells |
| Association of electroencephalogram epileptiform discharges during cardiac surgery with postoperative delirium: An observational study | Li, N. Liu, X. Gao, Y. Yin, L. Zhao, W. Ma, R. Ni, X. | Front Surg | 2022 |
cardiac surgery |
| Patients' and Relatives' Experiences of Delirium in the Intensive Care Unit-A Qualitative Study | Lange, S. Mędrzycka-Dąbrowska, W. Friganović, A. Religa, D. Krupa, S. | Int J Environ Res Public Health | 2022 |
Aged |
| Survey on Current Practice of Canadian Physicians Regarding the Investigation in Older Patients with Delirium | Laguë, A. Boucher, V. Joo, P. Yadav, K. Morasse, C. Émond, M. | Can Geriatr J | 2022 |
delirium |
| Clinical phenotypes of delirium in patients admitted to the cardiac intensive care unit | Ko, R. E. Kim, S. Lee, J. Park, S. Bae, D. Choi, K. H. Park, T. K. Chung, C. R. Yang, J. H. | PLoS One | 2022 |
*Delirium/epidemiology/etiology |
| Delirium, dementia, and depression (3D) assessment of older patients in the emergency department: 5-year survival analysis | Kılıçaslan, İ Thet, M. S. Karahacıoğlu, B. Sevim, M. Ülger, Z. Aslaner, M. A. Kılıçaslan, B. | Turk J Med Sci | 2022 |
Aged |
| Charles Bonnet Syndrome With Superimposed Delirium | Karson, C. Kang, C. Albrecht, B. Levin, G. | Cureus | 2022 |
antipsychotic |
| Prevalence and Long-Term Prognosis of Post-Intensive Care Syndrome after Sepsis: A Single-Center Prospective Observational Study | Inoue, S. Nakanishi, N. Sugiyama, J. Moriyama, N. Miyazaki, Y. Sugimoto, T. Fujinami, Y. Ono, Y. Kotani, J. | J Clin Med | 2022 |
Barthel Index |
| Mental health-related quality of life is related to delirium in intensive care patients | Hofhuis, J. G. M. Schermer, T. Spronk, P. E. | Intensive Care Med | 2022 |
Critical Care |
| Noise pareidolia test for predicting delirium in hospitalized older patients with cognitive decline | Hashimoto, Y. Kano, O. Ebihara, S. | Geriatr Gerontol Int | 2022 |
cognitive decline |
| Postoperative Delirium Severity and Recovery Correlate With Electroencephalogram Spectral Features | Guay, C. S. Kafashan, M. Huels, E. R. Jiang, Y. Beyoglu, B. Spencer, J. W. Geczi, K. Apakama, G. Ju, Y. S. Wildes, T. S. Avidan, M. S. Palanca, B. J. A. | Anesth Analg | 2022 | |
| Prevention and treatment of delirium in intensive care: Hermeneutics of experiences of the nursing team | Gómez Tovar, L. O. Henao-Castaño Á, M. Troche-Gutiérrez, I. Y. | Enferm Intensiva (Engl Ed) | 2022 |
*Critical Care |
| How do predisposing factors differ between delirium motor subtypes? A systematic review and meta-analysis | Ghezzi, E. S. Greaves, D. Boord, M. S. Davis, D. Knayfati, S. Astley, J. M. Sharman, R. L. S. Goodwin, S. I. Keage, H. A. D. | Age Ageing | 2022 |
Aged |
| Applying the geriatric 5Ms in critical care: the ICU-5Ms | Geen, O. Perrella, A. Rochwerg, B. Wang, X. M. | Can J Anaesth | 2022 |
Aged |
| Delirium in Persons With Dementia: Integrating the 4Ms of Age-Friendly Care as a Set Into the Care of Older People | Fick, D. M. Shrestha, P. | J Gerontol Nurs | 2022 |
Aged |
| The effect of melatonin on prevention of postoperative delirium after lower limb fracture surgery in elderly patients: a randomized double blind clinical trial | Fazel, M. R. Mofidian, S. Mahdian, M. Akbari, H. Razavizadeh, M. R. | Int J Burns Trauma | 2022 |
Melatonin |
| Risk factors for delirium after surgery for craniocerebral injury in the neurosurgical intensive care unit | Chen, R. Y. Zhong, C. H. Chen, W. Lin, M. Feng, C. F. Chen, C. N | World J Clin Cases | 2022 |
Brain injury |
| Risk factors and a nomogram model for postoperative delirium in elderly gastric cancer patients after laparoscopic gastrectomy | Chen, J. Ji, X. Xing, H. | World J Surg Oncol | 2022 |
Aged |
| Self-efficacy of caring for patients in the intensive care unit with delirium: Development and validation of a scale for intensive care unit nurses | Chang, Y. L. Hsieh, M. J. Chang, Y. C. Yeh, S. L. Chen, S. W. Tsai, Y. F. | Aust Crit Care | 2022 |
Delirium |
| A nurse-led intervention to reduce the incidence and duration of delirium among adults admitted to intensive care: A stepped-wedge cluster randomised trial | Brennan, K. Sanchez, D. Hedges, S. Lynch, J. Hou, Y. C. Al Sayfe, M. Shunker, S. A. Bogdanoski, T. Hunt, L. Alexandrou, E. He, S. Mai, H. Rolls, K. Frost, S. A. | Aust Crit Care | 2022 |
Delirium prevention |
| Association of cholinesterase activities and POD in older adult abdominal surgical patients | Bosancic, Z. Spies, C. D. Müller, A. Winterer, G. Piper, S. K. Heinrich, M | BMC Anesthesiol | 2022 |
Aged |
| Management of delirium in older adults: challenges and opportunities | Bingham, K. S. Flint, A. J. | 2022 |
Aged |
|
| Emergence delirium after intracranial neurosurgery- a prospective cohort study | Bharadwaj, S. Konar, S. Akash, V. S. Gopalakrishna, K. N. Chakrabarti, D. Kamath, S. | J Clin Neurosci | 2022 |
Adolescent |
| A novel approach for the detection of cognitive impairment and delirium risk in older patients undergoing spine surgery | Barreto Chang, O. L. Whitlock, E. L. Arias, A. D. Tsoy, E. Allen, I. E. Hellman, J. Bickler, P. E. Miller, B. Possin, K. L. | J Am Geriatr Soc | 2022 |
anesthesia and surgery |
| Temporal Variability in Inflammatory Gene Methylation and Delirium in Critically Ill Patients | Alexander, S. A. Conley, Y. P. Girard, T. D. McVerry, B. J. Ren, D. | Am J Crit Care | 2022 |
Adolescent |
| Machine Learning-Based Prediction Models for Delirium: A Systematic Review and Meta-Analysis | Xie, Q. Wang, X. Pei, J. Wu, Y. Guo, Q. Su, Y. Yan, H. Nan, R. Chen, H. Dou, X. | J Am Med Dir Assoc | 2022 |
Machine learning algorithm |
| Baseline Anxiety and Depression and Risk for ICU Delirium: A Prospective Cohort Study | Wu, T. T. Kooken, R. Zegers, M. Ko, S. Bienvenu, O. J. Devlin, J. W. van den Boogaard, M. | Crit Care Explor | 2022 |
anxiety |
| Preoperative Cognitive Impairment and Postoperative Delirium in Elderly Surgical Patients - a Retrospective Large Cohort Study | Weiss, Y. Zac, L. Refaeli, E. Ben-Yishai, S. Zegerman, A. Cohen, B. Matot, I. | Ann Surg | 2022 | |
| Goal-directed therapy based on rScO(2) monitoring in elderly patients with one-lung ventilation: a randomized trial on perioperative inflammation and postoperative delirium | Wang, J. Y. Li, M. Wang, P. Fang, P. | Trials | 2022 |
Aged |
| Impact of propofol versus sevoflurane on the incidence of postoperative delirium in elderly patients after spine surgery: study protocol of a randomized controlled trial | Wang, J. H. Lv, M. Zhang, H. X. Gao, Y. Chen, T. T. Wan, T. T. Wang, Y. L. | Trials | 2022 |
Aged |
| Impact of propofol versus sevoflurane on the incidence of postoperative delirium in elderly patients after spine surgery: study protocol of a randomized controlled trial | Wang, J. H. Lv, M. Zhang, H. X. Gao, Y. Chen, T. T. Wan, T. T. Wang, Y. L. | Trials | 2022 |
Aged |
| Potential Value of Serum Uric Acid in the Identification of Postoperative Delirium in Geriatric Patients Undergoing Knee Replacement | Wang, F. Tang, X. Wang, J. Liu, S. Wu, X. Dong, R. Lin, X. Wang, B. Bi, Y. | Front Aging Neurosci | 2022 |
Alzheimer-related biomarkers |
| Patient Outcomes After Delirium Screening and Incident Alzheimer's Disease or Related Dementias in Skilled Nursing Facilities | Vo, Q. T. Koethe, B. Holmes, S. Simoni-Wastila, L. Briesacher, B. A. | J Gen Intern Med | 2022 |
Alzheimer’s disease |
| Delirium in head trauma: looking for a culprit | Villani, E. R. Franza, L. Cianci, R. | Rev Recent Clin Trials | 2022 |
Delirium |
| Timing, Threshold, and Duration of Intraoperative Hypotension in Cardiac Surgery: Their Associations With Postoperative Delirium | Ushio, M. Egi, M. Fujimoto, D. Obata, N. Mizobuchi, S. | J Cardiothorac Vasc Anesth | 2022 |
Cardiac valvular surgery |
| Detecting delirium in nursing home residents using the Informant Assessment of Geriatric Delirium (I-AGeD): a validation pilot study | Urfer Dettwiler, P. Zúñiga, F. Bachnick, S. Gehri, B. de Jonghe, J. F. M. Hasemann, W. | Eur Geriatr Med | 2022 |
Aged |
| Association of preoperative frailty and postoperative delirium in older cancer patients undergoing elective abdominal surgery: a prospective observational study in Taiwan | Tsai, C. Y. Liu, K. H. Lai, C. C. Hsu, J. T. Hsueh, S. W. Hung, C. Y. Yeh, K. Y. Hung, Y. S. Lin, Y. C. Chou, W. C. | Biomed J | 2022 |
cancer |
| Delirium and Cortical Complexity: Divergent Changes in Alpha and Theta Bands | Tanabe, S. Parker, M. Lennertz, R. Pearce, R. A. Banks, M. I. Sanders, R. D. | J Gerontol A Biol Sci Med Sci | 2022 | |
| Escaping delirium: Designing an escape room active learning experience for geriatric resource nurses | Stoller, A. Iannuzzo, S. Davis, K. | Geriatr Nurs | 2022 |
Creative problem solving |
| Perivascular spaces visible on magnetic resonance imaging predict subsequent delirium in older patients | Song, Q. Zhao, Y. Lin, T. Yue, J. | Front Aging Neurosci | 2022 |
cerebral small vessel disease |
| Postoperative delirium does not affect cardiopulmonary exercise testing in aged patients undergoing cardiac valve surgery | Shimomoto, Y. Mukaiyama, K. Hori, T. Inaki, Y. Masai, T. Hayashi, Y. | JA Clin Rep | 2022 |
Cardiac rehabilitation |
| Silent cerebral ischemia detected by magnetic resonance imaging can predict postoperative delirium after total arch replacement for aneurysm | Shibagaki, K. Shirasaka, T. Sawada, J. Saijo, Y. Kunioka, S. Kikuchi, Y. Kamiya, H. | JTCVS Open | 2022 |
AAA, aortic arch aneurysm |
| Impact of delirium on the outcome of stroke: a prospective, observational, cohort study | Rollo, E. Brunetti, V. Scala, I. Callea, A. Marotta, J. Vollono, C. Frisullo, G. Broccolini, A. Calabresi, P. Della Marca, G. | J Neurol | 2022 |
Delirium |
| Association between non-English language and use of physical and chemical restraints among medical inpatients with delirium | Reppas-Rindlisbacher, C. Shin, S. Purohit, U. Verma, A. Razak, F. Rochon, P. Sheehan, K. Rawal, S. | J Am Geriatr Soc | 2022 | |
| Sedation, analgesia, and delirium management in Portugal: a survey and point prevalence study | Paulino, M. C. Pereira, I. J. Costa, V. Neves, A. Santos, A. Teixeira, C. M. Coimbra, I. Fernandes, P. Bernardo, R. Póvoa, P. Granja, C. | Rev Bras Ter Intensiva | 2022 |
*Analgesia |
| Acute kidney injury-associated delirium: a review of clinical and pathophysiological mechanisms | Pang, H. Kumar, S. Ely, E. W. Gezalian, M. M. Lahiri, S. | Crit Care | 2022 |
*Acute Kidney Injury |
| Delirium Development After Lung Transplantation: An Intraoperative Assessment | Ozay, H. Y. Bindal, M. Turkkan, S. Beyoglu, M. A. Yekeler, E. Turan, S. | Transplant Proc | 2022 |