What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Association of peripheral B cells and delirium: combined single-cell sequencing and Mendelian randomization analysis
- Authors
- Tan, S. Pan, S. Wei, L. Chen, W. Pan, B. Kong, G. Chen, J. Xie, Y.
- Year
- 2024
- Journal
- Front Neurol
- Abstract
BACKGROUND: Delirium seriously affects the prognosis of patients and greatly reduces the ability to work and live. Peripheral inflammatory events may contribute to the development of delirium, the mechanism of which is still unclear. There is a lack of effective diagnostic and treatments for delirium in clinical practice. The study aims to investigate alterations in peripheral immune cell subsets under inflammatory stress and to explore causal associations with delirium. METHODS: Single-cell transcriptional sequencing data of human peripheral blood mononuclear cells (PBMC) before and after lipopolysaccharide (LPS) intervention were processed by the Seurat package in R software. PBMC subsets and cellular markers were defined after downscaling and clustering by the Harmony algorithm to identify characteristic subsets in the context of inflammatory stress. Subsequently, a two-sample Mendelian randomization (MR) study was used to explore the causal associations of these inflammation-related PBMC subsets and their molecular phenotypes with delirium. Based on publicly available genetic data, the study incorporated 70 PBMC-associated immune traits, including 8 types of circulating immune cells, 33 B cell subsets and molecular phenotypes, 13 T cell subsets, and 16 B cell-associated cytokines. The results were also validated for robustness, heterogeneity, and horizontal pleiotropy. RESULTS: Under LPS-induced inflammatory stress, B cells, T cells, monocytes, and dendritic cells in human PBMC showed significant activation and quantitative changes. Of these, only lymphocyte and B cell counts were causally associated with delirium risk. This risk link is also seen in the TNF pathway. Further studies of B cells and their subsets revealed that this association may be related to unswitched memory B cells and CD27 expressed on memory B cells. Annotation of the screened SNPs revealed significant polymorphisms in CD27 and CD40 annotated by rs25680 and rs9883798, respectively. The functions of the key annotated genes may be related to the regulation of immune responses, cell differentiation, proliferation, and intercellular interactions. CONCLUSION: The present study revealed the potential possibility that B cell, memory B cell subset, and TNF-related molecules may be involved in the development of delirium due to peripheral inflammation, which can provide clues for further investigation of delirium prevention and treatment strategies.
- PMID
PMID:38379709
PMCID: PMC10876872
- Keywords
B cell
Mendelian randomization
Pbmc
delirium
inflammation
commercial or financial relationships that could be construed as a potential
conflict of interest.
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Psychiatric Etiologies and Approaches in Altered Mental Status Presentations: Insights from Consultation Liaison Psychiatry | Hamm, B. Rosenthal, L. J. | Semin Neurol | 2024 |
Altered mental status Psychiatry Delirium
|
| Bispectral Index Monitoring Effect on Delirium Occurrence and Nursing Quality Improvement in Post-anesthesia Care Unit Patients Recovering From General Anesthesia: A Randomized Controlled Trial | Huang, Y. Huang, L. Xu, J. Bao, Y. Qu, Y. Huang, Y. | Cureus | 2024 |
bispectral index |
| Impact of Frailty and Delirium Among Older Adults Admitted With Acute Decompensated Heart Failure | Irizarry-Caro, J. A. Kumar, M. Wang, Q. Rohant, N. Goyal, P. Damluji, A. A. Kirkpatrick, J. N. Kwak, M. J. | JACC Adv | 2024 |
acute decompensated heart failure |
| Improving hospice delirium guideline adoption through an understanding of barriers and facilitators: A mixed-methods study | Jackson, C. Malia, C. Zacharias, H. Dyson, J. Johnson, M. J. | PLoS One | 2024 |
Humans |
| Machine learning-based delirium prediction in surgical in-patients: a prospective validation study | Jauk, S. Kramer, D. Sumerauer, S. Veeranki, S. P. K. Schrempf, M. Puchwein, P. | JAMIA Open | 2024 |
clinical decision support
delirium
electronic health records
prediction algorithms
random forest
|
| Risk factors for postoperative delirium in patients with cardiac surgery | Kim, M. S. Kim, S. H. | Sci Prog | 2024 |
Humans |
| Delirium in the ICU: how much do we know? A narrative review | Liu, S. B. Wu, H. Y. Duan, M. L. Yang, R. L. Ji, C. H. Liu, J. J. Zhao, H. | Ann Med | 2024 |
*Delirium/diagnostic imaging/pathology/therapy |
| The role of C-reactive protein as a risk marker of postoperative delirium in older hip fracture patients: a prospective cohort study | Lozano-Vicario, L. Muñoz-Vázquez Á, J. Cedeno-Veloz, B. A. Romero-Ortuno, R. Galbete, A. Fernández-Irigoyen, J. Santamaría, E. Zambom-Ferraresi, F. Ortiz-Gómez, J. R. Hidalgo-Ovejero Á, M. Martínez-Velilla, N. | Eur Geriatr Med | 2024 |
C-reactive protein |
| Low-dose clonidine infusion to improve sleep in postoperative patients in the high-dependency unit. A randomised placebo-controlled single-centre trial | Liu, D. Hallt, E. Platz, A. Humblet, A. Lassig-Smith, M. Stuart, J. Fourie, C. Livermore, A. McConnochie, B. Y. Starr, T. Herbst, K. Woods, C. A. Pincus, J. M. Reade, M. C. | Intensive Care Med | 2024 |
Clonidine |
| A nomogram for predicting the risk of postoperative delirium in individuals undergoing cardiovascular surgery | Liu, C. Zhang, L. Tang, W. Zhao, S. Li, M. Li, J. Shao, Y. | Eur J Neurol | 2024 |
cardiovascular surgery |
| Comparative Diagnostic Accuracy of Nursing Delirium Screening Scale Versus Confusion Assessment Method for Postoperative Delirium: A Systematic Review and Meta-Analysis | Lin, C. J. Fick, D. M. Traynor, V. Chen, Y. C. Hsiang, H. F. Chiu, H. Y. | J Clin Nurs | 2024 |
Confusion Assessment Method |
| The clinical value of nonpharmacological interventions for preventing postoperative delirium: a narrative review | Li, T. Feng, Z. Hou, Y. Li, P. | Minerva Anestesiol | 2024 |
Humans |
| N-methyl-d-aspartate (NMDA) receptor antagonists for treatment of catatonia in adults: Narrative review | Lee, J. H. Suzuki, J. | Gen Hosp Psychiatry | 2024 |
Amantadine |
| Postoperative Delirium Following Posterior Lumbar Spinal Fusion: Epidemiology, Risk Factors, and Associated Complications | Knebel, A. Singh, M. Rasquinha, R. Daher, M. Nassar, J. E. Hanna, J. Diebo, B. G. Daniels, A. H. | World Neurosurg | 2024 |
Complications |
| Co-designing a digital family-led intervention for delirium prevention and management in adult critically ill patients: An application of the double diamond design process | Johnson, G. U. Towell-Barnard, A. McLean, C. Robert, G. Ewens, B. | Int J Nurs Stud | 2024 |
Co-design |
| Reduction of Rehospitalization With Addition of Geriatrics/Transitions of Care Consult Service | Jackson, A. E. Brubaker, A. N. Coffey, C. R. Kalender-Rich, J. L. | J Am Med Dir Assoc | 2024 |
Long-term care |
| Postoperative neurocognitive disorders in ambulatory surgery: a narrative review | In, J. Chen, B. Bae, H. Kinjo, S. | Korean J Anesthesiol | 2024 |
Humans |
| Preoperative assessment of hyperactive delirium risk after head and neck surgery with free tissue transfer reconstruction | Imai, T. Takasago, T. Nakanome, A. Morita, S. Miyakura, Y. Sasaki, K. Ito, K. Goto, T. Asada, Y. | Auris Nasus Larynx | 2024 |
Head and neck neoplasms |
| Long-Term Impact of Delirium on the Risk of Dementia in Hospitalized Older Patients: A Real-World Multicenter Study | Hwang, G. Park, C. Son, S. J. Roh, H. W. Hwang, J. Y. Jang, J. W. Jo, Y. T. Byeon, G. Youn, H. Park, R. W. | Am J Geriatr Psychiatry | 2024 |
Alzheimer’s disease |
| Comprehensive signal detection of delirium-associated medication using the Food and Drug Administration Adverse Event Reporting System | Hatano, M. Sogawa, R. Shin, K. Esumi, S. Ishikawa, A. Mizumura, R. Araki, H. Yamada, S. | Gen Hosp Psychiatry | 2024 |
Humans |
| Inhibited hypoxia-inducible factor by intraoperative hyperglycemia increased postoperative delirium of aged patients: A review | Han, Y. Ji, B. Leng, Y. Xie, C. | Medicine (Baltimore) | 2024 |
Humans |
| Development and Validation of Machine Learning Models to Predict Postoperative Delirium Using Clinical Features and Polysomnography Variables | Ha, W. S. Choi, B. K. Yeom, J. Song, S. Cho, S. Chu, M. K. Kim, W. J. Heo, K. Kim, K. M. | J Clin Med | 2024 |
machine learning |
| Association between baseline serum bicarbonate and the risk of postoperative delirium in patients undergoing cardiac surgery in the ICU: a retrospective study from the MIMIC-IV database | Guo, P. Ma, Y. Su, W. Xie, D. Li, X. Wang, K. Wang, P. | BMC Anesthesiol | 2024 |
Humans |
| Non-pharmacological delirium detection and management interventions for informal caregivers of older people at home: A scoping review protocol | Fox, M. T. Maimets, I. K. Butler, J. I. Sidani, S. Godfrey, C. | PLoS One | 2024 |
Humans |
| Delirium in nursing home residents: is there a role of antidepressants? A cross sectional study | Fedecostante, M. Balietti, P. Di Santo, S. G. Zambon, A. Marengoni, A. Morandi, A. Beccacece, A. Bellelli, G. Cherubini, A. | BMC Geriatr | 2024 |
Humans |
| The use of peripheral nerve block decrease incidence of postoperative cognitive dysfunction following orthopedic surgery: A systematic review and meta-analysis | Deng, L. Jiao, B. Cai, J. Xu, X. Chen, M. Yan, C. Zhu, T. Liu, J. Ma, D. Chen, C. | BMC Anesthesiol | 2024 |
Humans |
| Optimizing anesthesia management based on early identification of electroencephalogram burst suppression risk in non-cardiac surgery patients: a visualized dynamic nomogram | Chen, J. Li, W. Chen, Q. Zhou, Z. Chen, C. Hu, Y. Si, Y. Zou, J. | Ann Med | 2024 |
Humans |
| Routine cognitive screening for older people undergoing major elective surgery: Benefits, risks and costs | Chan, L. K. Chuan, A. Berney, C. R. Chan, D. K. | Anaesth Intensive Care | 2024 |
Humans |
| Prevalence and risk factors of subsyndromal delirium in ICU: A systematic review and meta-analysis | Ma, X. Cheng, H. Zhao, Y. Zhu, Y. | Intensive Crit Care Nurs | 2024 |
Intensive care unit |
| Predisposing and precipitating factors for the development of postoperative delirium in critically ill patients in a university intensive care unit | Marques, D. M. Alves, Ddsb Vernaglia, T. V. C. | Rev Lat Am Enfermagem | 2024 |
Humans |
| Diagnostic test accuracy of screening tools for the detection of neurocognitive disorders in older adults post-trauma: A protocol for a systematic review | Merriman, N. A. Walsh, M. E. O'Regan, N. Carrigan, M. Hickey, P. Brent, L. Blake, C. | HRB Open Res | 2024 |
cognition |
| How much risk does delirium represent for the development of dementia?: Retrospective cohort study from over 260,000 patients record in a solitary institution | Minami, H. Toyoda, K. Hata, T. Nishihara, M. Neo, M. Nishida, K. Kanazawa, T. | Front Psychiatry | 2024 |
cognitive decline |
| Effectiveness of the ABCDEF Bundle to Manage and Prevent Delirium: Pre- and Postintervention Quasi-Experimental Study | Nagy Nagm Eldean, T. Hassan Bakri, M. Anwar Abdel Aziz, M. Shalaby Khalaf, G. | Crit Care Nurs Q | 2024 |
Humans |
| C reactive protein albumin ratio as a new predictor of postoperative delirium after cholecystectomy for acute cholecystitis | Nakatake, R. Funatsuki, T. Koshikawa, Y. Okuyama, T. Ishizaki, M. Takekita, Y. Kato, M. Kitade, H. | Sci Rep | 2024 |
Humans |
| The impact of preoperative psychiatric intervention for postoperative delirium after major oral and maxillofacial surgery with free flap reconstruction | Nitta, Y. Sanuki, T. Sugino, S. Sugimoto, M. Kido, K. | J Stomatol Oral Maxillofac Surg | 2024 |
Free flap reconstruction |
| Impact of beta-blocker usage on delirium in patients with sepsis in ICU: a cross-sectional study | Ouyang, H. Wang, X. Deng, D. Wang, Q. Yu, Y. | Front Med (Lausanne) | 2024 |
ICU stay |
| Utilization of NIRS Monitor to Compare the Regional Cerebral Oxygen Saturation Between Dexmedetomidine and Propofol Sedation in Mechanically Ventilated Critically ill Patients with Sepsis- A Prospective Randomized Control Trial | Patidar, A. K. Khanna, P. Kashyap, L. Ray, B. R. Maitra, S. | J Intensive Care Med | 2024 |
delirium |
| Postoperative Delirium and Neurocognitive Disorders: A Comprehensive Review of Pathophysiology, Risk Factors, and Management Strategies | Paunikar, S. Chakole, V. | Cureus | 2024 |
cognitive impairment |
| Preoperative serum ferritin as a biomarker for predicting delirium among elderly patients receiving non-cardiac surgery: a retrospective cohort study | Ruan, X. Li, Y. Yuan, M. Li, H. Lou, J. Liu, Y. Cao, J. Ma, Y. Mi, W. Zhang, X. | Transl Psychiatry | 2024 |
Humans |
| Circadian disturbances, anxiety and motor disturbances differentiate delirium superimposed on dementia from dementia-only | Schnorr, T. Fleiner, T. Trumpf, R. Prüter-Schwarte, C. Fanselow, J. Zijlstra, W. Haussermann, P. | Front Psychiatry | 2024 |
acute hospital |
| Real-World Adherence to a Delirium Screening Test Administered by Nurses and Medical Staff during Routine Patient Care | Soboh, R. Rotfeld, M. Gino-Moor, S. Jiries, N. Ginsberg, S. Oliven, R. | Brain Sci | 2024 |
Radar |
| Dexmedetomidine for Postoperative Delirium Prevention in the Older Adult: An Integrative Review | Strada, A. L. Tevay, A. Scoggins, M. Gonzalez, K. | Aana j | 2024 |
Humans |
| Improving delirium assessments in acute senior health: A quality improvement project for care of the older person | Taylor, C. Peakman, G. Mackinnon, L. Mohamadzade, N. Han, W. Mackie, L. Gandhi, J. Mitchell, O. Bateman-Champain, C. Hetherington, J. Belarbi, F. Alg, G. | BMC Geriatr | 2024 |
Alzheimer’s disease |
| Postoperative delirium among elderly elective orthopedic patients in Addis Ababa Ethiopia: a multicentere longitudinal study | Tekletsadik, Y. A. Workineh, S. A. Gesso, A. S. Hirbo, H. S. | BMC Anesthesiol | 2024 |
Humans |
| Effect of optimizing cerebral oxygen saturation on postoperative delirium in older patients undergoing one-lung ventilation for thoracoscopic surgery | Teng, P. Liu, H. Xu, D. Feng, X. Liu, M. Wang, Q. | J Int Med Res | 2024 |
Humans |
| Persistent delirium is associated with cerebrospinal fluid markers of neuronal injury | Tsui, A. Johnstone, B. Heslegrave, A. Zetterberg, H. Watne, L. O. Neerland, B. E. Krogseth, M. Cunningham, C. MacLullich, A. Muniz Terrera, G. Davis, D. Caplan, G. | Brain Commun | 2024 |
CSF biomarkers |
| A Retrospective Study Establishing a Nomogram Predictive Model for Postoperative High-Activity Delirium After Non-Cardiac Surgery | Tu, Y. Du, W. Pan, Y. Zhang, X. Mo, Y. Sun, C. Wang, J. | Neuropsychiatr Dis Treat | 2024 |
Pacu |
| Safe Landing: Feasibility and Safety of Operating Room Extubation in Minimally Invasive Cardiac Valve Surgery | Wang, C. C. DeBose-Scarlett, A. Irlmeier, R. Ye, F. Siegrist, K. Shah, A. S. Kingeter, M. | J Cardiothorac Vasc Anesth | 2024 |
intubation duration |
| Intraoperative hypotension and postoperative delirium in elderly male patients undergoing laryngectomy: a single-center retrospective cohort study | Wang, Y. Chen, K. Ye, M. Shen, X. | Braz J Anesthesiol | 2024 |
Hypotension |
| Perioperative Risk Factors for Postoperative Delirium in Non-Dementia Older Patients after Non-Cardiac Surgery and Anesthesia: A Prospective Study | Wattanaboot, N. Kuawatcharawong, W. Permsakmesub, P. | Ann Geriatr Med Res | 2024 |
Postoperative delirium |
| Association of preoperative frailty with risk of postoperative delirium in older patients undergoing craniotomy: a prospective cohort study | Wei, L. Liu, M. Zhang, S. Chen, Y. Wu, M. Chen, X. Liu, J. He, Y. Yang, X. Xian, J. | BMC Surg | 2024 |
Humans |
| Geriatric nutritional risk index predicts postoperative delirium in elderly: A meta-analysis | Xie, S. Wu, Q. | Saudi Med J | 2024 |
Humans |
| Intensive care unit interventions to promote sleep and circadian biology in reducing incident delirium: a scoping review | Wilcox, M. E. Burry, L. Englesakis, M. Coman, B. Daou, M. van Haren, F. M. Ely, E. W. Bosma, K. J. Knauert, M. P. | Thorax | 2024 |
Humans |
| Theory-based and evidence-based nursing interventions for the prevention of ICU-acquired weakness in the intensive care unit: A systematic review | Xu, Q. Tan, J. Wang, Y. Tang, M. | PLoS One | 2024 |
Humans |
| Transradial versus transfemoral access for middle meningeal artery embolization: Choice of the access route considering delirium in the elderly | Yamamoto, M. Fujiwara, G. Takezawa, H. Uzura, Y. Yokoya, S. Oka, H. | Surg Neurol Int | 2024 |
Chronic subdural hematoma |
| The effect of perioperative dexmedetomidine on postoperative delirium in adult patients undergoing cardiac surgery with cardiopulmonary bypass: a systematic review and meta-analysis of randomized controlled trials | Zhuang, X. Fu, L. Luo, L. Dong, Z. Jiang, Y. Zhao, J. Yang, X. Hei, F. | BMC Anesthesiol | 2024 |
Adult |
| Incidence and associated factors of delirium after primary total joint arthroplasty in elderly patients: A systematic review and meta-analysis | Zhang, Y. Yu, Y. Han, Z. Diao, L. Zhao, R. Liu, J. Luo, Y. Wu, H. Yang, Y. | Medicine (Baltimore) | 2024 |
Aged |
| The effect of two different modes of anaesthesia maintenance on postoperative delirium in elderly patient with low preoperative mini-cog score | Duran, H. T. Kızılkaya, M. Aydinli, A. Osmantevfik, S. Taştan, S. Kılınç, OÖ Pirhan, Y. | BMC Anesthesiol | 2024 |
Aged |
| Extracellular Vesicle MicroRNAs as Predictive Biomarkers in Postoperative Delirium After Spine Surgery: Preliminary Study | Cho, Y. E. Kim, J. Vorn, R. Cho, H. Baek, W. Park, H. Yun, S. Kim, H. S. Cashion, A. K. Gill, J. Koo, B. N. Lee, H. | J Gerontol A Biol Sci Med Sci | 2024 |
Humans |
| Exploring the role of calf circumference as a predisposing factor for intra-hospital delirium: investigating potential gender differences: revealing potential gender variances | Ceolin, C. Papa, M. V. Simonato, C. Cazzavillan, S. Vergadoro, M. Trapella, G. S. Sermasi, R. De Rui, M. Noale, M. Zanforlini, B. M. Curreri, C. Bertocco, A. Devita, M. Sergi, G. Coin, A. | BMC Geriatr | 2024 |
Humans |
| Neurophysiological patterns reflecting vulnerability to delirium subtypes: a resting-state EEG and event-related potential study | Boord, M. S. Feuerriegel, D. Coussens, S. W. Davis, D. H. J. Psaltis, P. J. Garrido, M. I. Bourke, A. Keage, H. A. D. | Brain Commun | 2024 |
Eeg |
| Delirium in Lower Limb Trauma: The Incidence and Risk Factors in a Prospective Observational Study | Balachandran, A. Nagar, M. Behera, P. Kashyap, P. | Indian J Orthop | 2024 |
adults |
| Diurnal variation of postoperative delirium in elderly patients undergoing esketamine anesthesia for elective noncardiac surgery: a randomized clinical trial | Zhang, Y. Chen, R. Tang, S. Sun, T. Yu, Y. Shi, R. Wang, K. Zeng, Z. Liu, X. Meng, Q. Xia, Z. | Int J Surg | 2024 |
Humans |
| Recent developments in delirium after oral and maxillofacial free-flap reconstruction | Zhang, R. Zhang, W. Ren, Y. Yu, J. Li, L. Zhang, Y. | J Stomatol Oral Maxillofac Surg | 2024 |
Oral and maxillofacial free-flap reconstruction |
| A longitudinal multimodal MRI study of the visual network in postoperative delirium | Zhang, G. Qi, B. Li, H. Zhang, X. Chen, J. Li, H. Jing, B. Huang, H. | Brain Imaging Behav | 2024 |
Frontal glioma |
| Association between Intraoperative Hypotension and Postoperative Delirium: A Retrospective Cohort Analysis | Zarour, S. Weiss, Y. Abu-Ghanim, M. Iacubovici, L. Shaylor, R. Rosenberg, O. Matot, I. Cohen, B. | Anesthesiology | 2024 |
Humans |
| Incidence and relative risk of delirium after major surgery for patients with pre-operative depression: a systematic review and meta-analysis | Diep, C. Patel, K. Petricca, J. Daza, J. F. Lee, S. Xue, Y. Kremic, L. Xiao, M. Z. X. Pivetta, B. Vigod, S. N. Wijeysundera, D. N. Ladha, K. S. | Anaesthesia | 2024 |
delirium |
| Pharmacologic Treatment Strategies for Delirium in Hospitalized Adults: Past, Present, and Future | Devlin, J. W. | Semin Neurol | 2024 |
Delirium Cognitive decline Non-pharmacological interventions Risk factors ICU Delirium |
| Reperfusion therapy and risk of post-stroke delirium | Czyzycki, M. Pera, J. Dziedzic, T. | Neurol Res | 2024 |
Delirium |
| Implementation of delirium screening in the emergency department: A qualitative study with early adopters | Chary, A. N. Bhananker, A. R. Brickhouse, E. Torres, B. Santangelo, I. Godwin, K. M. Naik, A. D. Carpenter, C. R. Liu, S. W. Kennedy, M. | J Am Geriatr Soc | 2024 |
delirium |
| Practical prognostic tools to predict the risk of postoperative delirium in older patients undergoing cardiac surgery: visual and dynamic nomograms | Bah, C. S. Mbambara, B. Xie, X. Li, J. Iddi, A. K. Chen, C. Jiang, H. Feng, Y. Zhong, Y. Zhang, X. Xia, H. Yan, L. Si, Y. Zhang, J. Zou, J. | J Clin Monit Comput | 2024 |
Cardiac surgery |
| Validation of the delirium diagnostic tool-provisional (DDT-Pro) in geriatric medical inpatients with diagnostic permutations of the 3Ds with and without delirium | Botero Urrea, M. González, M. C. Villa García, M. M. Alviz Núñez, M. Velásquez-Tirado, J. D. Ocampo, M. V. Trzepacz, P. T. Franco, J. G. | J Psychosom Res | 2024 |
Humans Female |
| Delirium Mediated the Association Between a History of Falls and Short-Term Mortality Risk in Critically Ill Ischemic Stroke Patients | Cheng, H. Xu, X. Tang, Y. Yang, X. Ling, Y. Tan, S. Wang, Z. Ming, W. K. Lyu, J. | Clin Nurs Res | 2024 |
Icu |
| Risk factors for postoperative delirium in frail elderly patients undergoing on-pump cardiac surgery and development of a prediction model-a prospective observational study | Ding, Y. Gao, J. Ge, Y. Huang, T. Zhang, Y. | Front Cardiovasc Med | 2024 |
cardiac surgery |
| Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial | Fathy, W. Hussein, M. Elanwar, R. Elmoutaz, H. Abdelsadek, D. A. Kassim, D. Y. | BMC Anesthesiol | 2024 |
Humans |
| Predicting postoperative delirium assessed by the Nursing Screening Delirium Scale in the recovery room for non-cardiac surgeries without craniotomy: A retrospective study using a machine learning approach | Giesa, N. Haufe, S. Menk, M. Weiß, B. Spies, C. D. Piper, S. K. Balzer, F. Boie, S. D. | PLOS Digit Health | 2024 |
Postoperative Delirium Risk factors Non-linear machine learning Fluctuation Recovery Nurse Screening Delirium Scale |
| A Comparative Analysis of the Effects of Haloperidol and Dexmedetomidine on QTc Interval Prolongation during Delirium Treatment in Intensive Care Units | Haspolat, A. Polat, F. Köprülü, AŞ | J Crit Care Med (Targu Mures) | 2024 |
QTc interval |
| Effect of mannitol on postoperative delirium in patients undergoing coronary artery bypass graft: a randomised controlled trial | Hemmati Maslakpak, M. Negargar, S. Farbod, A. Khalili, A. Bilehjani, E. Alinejad, V. Faravan, A. | Open Heart | 2024 |
Humans |
| Assessing Delirium Severity in Dementia: Item Development and Psychometric Validation for a Delirium Severity Instrument | Hshieh, T. Schulman-Green, D. Fong, T. G. Metzger, E. Arias, F. Helfand, B. Marcantonio, E. Schmitt, E. Tabloski, P. Jones, R. N. Inouye, S. K. | J Gerontol Nurs | 2024 |
Humans |
| The development of a family-led novel intervention for delirium prevention and management in the adult intensive care unit: A co-design qualitative study | Johnson, G. U. Towell-Barnard, A. McLean, C. Ewens, B. | Aust Crit Care | 2024 |
Co-design |
| Disparities in Delirium across the Continuum of Care and Associations with Social Determinants of Health | Khanna, A. Govil, M. Ayele, N. Saadi, A. | Semin Neurol | 2024 |
Delirium identification Delirium treatment Disparities Social-ecological model Social determinants of health |
| The effect of non-steroidal anti-inflammatory drugs on postoperative delirium: a meta-analysis | Kim, S. Y. Na, H. S. Ryu, J. H. Shin, H. J. | Korean J Anesthesiol | 2024 |
Cognitive dysfunction |
| Management of delirium in acute stroke patients: a position paper by the Austrian Stroke Society on prevention, diagnosis, and treatment | Kneihsl, M. Berger, N. Sumerauer, S. Asenbaum-Nan, S. Höger, F. S. Gattringer, T. Enzinger, C. Aigner, M. Ferrari, J. Lang, W. | Ther Adv Neurol Disord | 2024 |
acute stroke |
| Assessment of cognition: dementia and delirium : In consideration of the AWMF guidelines 038-013 and 084-002LG | Krupp, S. Iglseder, B. | Z Gerontol Geriatr | 2024 |
Cognitive impairments |
| Retrospective comparison of the effects of remimazolam and dexmedetomidine on postoperative delirium in elderly patients undergoing orthopedic surgery of the lower extremities under spinal anesthesia | Lee, S. Oh, C. Jung, J. Hong, B. Jo, Y. Lee, S. Lim, C. Baek, S. Shin, M. Seo, H. Chung, W. | J Anesth | 2024 |
Benzodiazepines |
| Cluster nursing care based on 10S continuous quality improvement reduces incidence of postoperative delirium in BPH patients | Li, R. X. Liu, J. Jin, P. Ye, X. Q. Xu, S. | Zhonghua Nan Ke Xue | 2024 |
Humans |
| Elderly patients with dysphagia in the intensive care unit: Association between malnutrition and delirium | Liang, X. Li, X. Cheng, H. Wei, F. Li, T. Li, Y. Huang, Y. Lyu, J. Wang, Y. | Nurs Crit Care | 2024 |
critical care nursing |
| Global Research Trends in Postoperative Delirium and Its Risk Factors: A Bibliometric and Visual Analysis | Liu, X. Huangfu, Z. Zhang, X. Ma, T. | J Perianesth Nurs | 2024 |
bibliometrics |
| Intensive care nurses' perceptions and awareness of delirium and delirium prevention guidelines | Meghani, S. Timmins, F. | Nurs Crit Care | 2024 |
Humans |
| Characteristics associated with effectiveness in postoperative delirium research: a systematic review of randomised controlled trials with meta-regression and meta-analysis | Meng, L. Zhao, X. Sun, Y. Cheng, S. Bao, L. Fang, K. Yu, Q. Zheng, Y. Wang, J. Luo, M. Gunderman, D. Vuckovic, N. Sidhu, A. S. Li, J. Li, G. Wolfe, J. W. Liu, Z. Adams, D. C. | Br J Anaesth | 2024 |
Humans |
| Electroencephalography as a tool for assessing delirium in hospitalized patients: A single-center tertiary hospital experience | Mohamad Faizal, N. S. Tan, J. K. Tan, M. M. Khoo, C. S. Sahibulddin, S. Z. Zolkafli, N. Hod, R. Tan, H. J. | J Cent Nerv Syst Dis | 2024 |
Delirium |
| Common molecular and pathophysiological underpinnings of delirium and Alzheimer's disease: molecular signatures and therapeutic indications | Mosharaf, M. P. Alam, K. Gow, J. Mahumud, R. A. Mollah, M. N. H. | BMC Geriatr | 2024 |
Humans |
| Evaluation of postoperative delirium in geriatric patients given acetaminophen with and without melatonin: A retrospective cohort study | Muehrcke, M. N. Blackwelder, R. S. Weeda, E. R. Furlough, L. A. Shelton, J. E. Brace, S. M. Bragg, S. W. | Int J Psychiatry Med | 2024 |
comorbidity |
| Effect of intranasal insulin on perioperative cognitive function in older adults: a randomized, placebo-controlled, double-blind clinical trial | Sun, M. Ruan, X. Zhou, Z. Huo, Y. Liu, M. Liu, S. Cao, J. Liu, Y. H. Zhang, X. Ma, Y. L. Mi, W. | Age Ageing | 2024 |
Humans |
| Predictive model of risk factors for 28-day mortality in patients with sepsis or sepsis-associated delirium based on the MIMIC-IV database | Zhang, L. Li, X. Huang, J. Yang, Y. Peng, H. Yang, L. Yu, X. | Sci Rep | 2024 |
Humans |
| Exploring Causal Links Between Gut Microbiota and Geriatric Syndromes: A Two-Sample Mendelian Randomization Analysis | Yao, Q. Chen, L. Cai, Y. Li, C. Wen, S. Yang, C. Zhang, Q. Zeng, Y. Zheng, S. Zou, J. Huang, G. Zeng, Q. | Int J Med Sci | 2024 |
Humans |
| Intranasal administration of insulin on the incidence of postoperative delirium in middle-aged patients undergoing elective on-pump cardiac surgery (INIPOD-MOPS): a prospective double-blinded randomized control study protocol | Yang, M. Yang, G. Lu, T. Cao, L. Xiao, C. Liang, Y. Ding, J. Jiang, X. Wang, W. Chen, F. Du, Z. Li, H. | Trials | 2024 |
Humans |
| Integrated Multi-Omics Analysis of Cerebrospinal Fluid in Postoperative Delirium | Tripp, B. A. Dillon, S. T. Yuan, M. Asara, J. M. Vasunilashorn, S. M. Fong, T. G. Inouye, S. K. Ngo, L. H. Marcantonio, E. R. Xie, Z. Libermann, T. A. Otu, H. H. | Biomolecules | 2024 |
Humans |
| Sex-stratified analyses of comorbidities associated with an inpatient delirium diagnosis using real world data | Sirota, M. Kodama, L. Woldemariam, S. Tang, A. Li, Y. Kornak, J. Allen, I. E. Raphael, E. Oskotsky, T. | Res Sq | 2024 |
Delirium Older Adults Comorbidities Mental Health Inpatient delirium |
| Reasons influencing the nurses' prioritization process while preventing and managing delirium: findings from a qualitative study | Sist, L. Ugenti, N. V. Chiappinotto, S. Messina, R. Rucci, P. Palese, A. | Aging Clin Exp Res | 2024 |
Humans |