Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Role of Intraoperative Neuromonitoring to Predict Postoperative Delirium in Cardiovascular Surgery
Authors
Al-Qudah, A. M. Ta'ani, O. A. Thirumala, P. D. Sultan, I. Visweswaran, S. Nadkarni, N. Kiselevskaya, V. Crammond, D. J. Balzer, J. Anetakis, K. M. Shandal, V. Subramanium, K. Subramanium, B. Sadhasivam, S.
Year
2023
Journal
J Cardiothorac Vasc Anesth
Abstract

OBJECTIVE: Postoperative delirium (POD) can occur in up to 50% of older patients undergoing cardiovascular surgery, resulting in hospitalization and significant morbidity and mortality. This study aimed to determine whether intraoperative neurophysiologic monitoring (IONM) modalities can be used to predict delirium in patients undergoing cardiovascular surgery. DESIGN: Adult patients undergoing cardiovascular surgery with IONM between 2019 and 2021 were reviewed retrospectively. Delirium was assessed multiple times using the Intensive Care Delirium Screening Checklist (ICDSC). Patients with an ICDSC score ≥4 were considered to have POD. Significant IONM changes were evaluated based on a visual review of electroencephalography (EEG) and somatosensory evoked potentials data and documentation of significant changes during surgery. SETTING: University of Pittsburgh Medical Center hospitals. PARTICIPANTS: Patients 18 years old and older undergoing cardiovascular surgery with IONM monitoring. MEASUREMENTS AND MAIN RESULTS: Of the 578 patients undergoing cardiovascular surgery with IONM, 126 had POD (21.8%). Significant IONM changes were noted in 134 patients, of whom 49 patients had delirium (36.6%). In contrast, 444 patients had no IONM changes during surgery, of whom 77 (17.3%) patients had POD. Upon multivariate analysis, IONM changes were associated with POD (odds ratio 2.12; 95% CI 1.31-3.44; p < 0.001). Additionally, baseline EEG abnormalities were associated with POD (p = 0.002). CONCLUSION: Significant IONM changes are associated with an increased risk of POD in patients undergoing cardiovascular surgery. These findings offer a basis for future research and analysis of EEG and somatosensory evoked potential monitoring to predict, detect, and prevent POD.

PMID

PMID

Keywords

Eeg, Ionm, Ssep, cardiac, delirium, postoperative

Page(s)
Issue

Search:
Total Records Found: 5897, showing 100 per page
TitleAuthorsJournalYearKeywords
Efficacy and Tolerability of Atypical Antipsychotics in the Treatment of Delirium: A Systematic Review of the Literature. Rivière, J. van der Mast, R. C. Vandenberghe, J. Van Den Eede, F. Psychosomatics 2018

aged
article
comparative study
controlled study
delirium
drug combination
drug therapy
extrapyramidal symptom
female
human
incidence
male
Medline
meta analysis
open study
randomized controlled trial (topic)
sedation
systematic review
amisulpride
aripiprazole
asenapine
clozapine
haloperidol
iloperidone
lurasidone
olanzapine
paliperidone
perospirone
placebo
quetiapine
risperidone
sertindole
ziprasidone
zotepine

Outcomes of Prehospital Chemical Sedation With Ketamine Versus Haloperidol and Benzodiazepine or Physical Restraint Only. O'Connor, L. Rebesco, M. Robinson, C. Gross, K. Castellana, A. O'Connor, M. J. Restuccia, M. Preshosp Emerg Care 2018

agitated delirium
ketamine
restraint
sedation

Just another piece of paperwork": perceptions of clinicians on delirium screening following hip fracture repair elicited in focus groups. Oberai, T. Killington, M. Laver, K. Crotty, M. Jaarsma, R. Int Psychogeriatr 2018

aging
cognitive impairment
delirium
qualitative research

Altered mental status predicts mortality in cardiogenic shock – results from the CardShock study. Kataja, A. Tarvasmäki, T. Lassus, J. Køber, L. Sionis, A. Spinar, J. Parissis, J. Carubelli, V. Cardoso, J. Banaszewski, M. Marino, R. Nieminen, M. S. Mebazaa, A. Harjola, V. P. European Heart Journal: Acute Cardiovascular Care 2018

NCT01374867
adult
aged
arterial pH
article
cardiogenic shock
cardiovascular mortality
clinical assessment
female
heart left ventricle ejection fraction
human
lactate blood level
major clinical study
male
mental health
multicenter study
observational study
prevalence
priority journal
prospective study
systolic blood pressure

Nurses' and physicians' approaches to delirium management in the intensive care unit: A focus group investigation. Collet, M. O. Thomsen, T. Egerod, I. Aust Crit Care 2018

Delirium
Focus groups
Hermeneutics
Intensive care unit
Nursing care
Pharmacological action
Qualitative research

Low Plasma Cholinesterase Activity is Associated With Postoperative Delirium After Noncardiac Surgery in Elderly Patients: A Prospective Observational Study. Zhao, B. Ni, Y. Tian, X. Psychosomatics 2018

aged
alcohol consumption
APACHE
article
cholinesterase blood level
cohort analysis
comorbidity
confounding variable
controlled study
enzyme activity
female
Han Chinese
human
human tissue
incidence
major clinical study
male
multivariate logistic regression analysis
observational study
postoperative delirium
prospective study
risk factor
surgery
surgical intensive care unit
acetylcholinesterase
biological marker
cholinesterase
endogenous compound

Propofol compared with sevoflurane general anaesthesia is associated with decreased delayed neurocognitive recovery in older adults. Zhang, Y. Shan, G. J. Zhang, Y. X. Cao, S. J. Zhu, S. N. Li, H. J. Ma, D. Wang, D. X. British Journal of Anaesthesia 2018

ChiCTR-IPR-15006209
NCT02662257
propofol
sevoflurane
aged
anesthetic recovery
APACHE
article
bispectral index
bradycardia
bronchospasm
cancer surgery
cognition
comparative study
controlled study
delayed neurocognitive recovery
electrocardiogram
emergence agitation
end tidal carbon dioxide tension
female
general anesthesia
heart ventricle extrasystole
human
hypertension
hypotension
intraoperative monitoring
major clinical study
male
multicenter study
neuropsychological test
oxygen saturation
patient safety
perioperative period
postoperative cognitive dysfunction
postoperative nausea and vomiting
priority journal
randomized controlled trial
tachycardia
very elderly

Effect of dexmedetomidine on postoperative delirium in elderly patients undergoing hip fracture surgery. Xie, S. Xie, M. Pak J Pharm Sci 2018
Development and Validation of an Electronic Health Record-Based Machine Learning Model to Estimate Delirium Risk in Newly Hospitalized Patients Without Known Cognitive Impairment. Wong, A. Young, A. T. Liang, A. S. Gonzales, R. Douglas, V. C. Hadley, D. JAMA Netw Open 2018
Sedative drugs used for mechanically ventilated patients in intensive care units: a systematic review and network meta-analysis. Wang, H. Wang, C. Wang, Y. Tong, H. Feng, Y. Li, M. Jia, L. Yu, K. Curr Med Res Opin 2018

Sedative drugs
intensive care units
mechanical ventilation
mortality
network meta-analysis
systematic review

Prediction of length of hospital stay and mortality in patients with delirium: A prospective cohort analysis of 200 ICU patients. Tian, J. Chen, X. Liu, D. Journal of Biological Regulators and Homeostatic Agents 2018

adult
age
aged
article
cohort analysis
critically ill patient
disease association
female
hospital mortality
human
intensive care psychosis
length of stay
major clinical study
male
observational study
prediction
probability
prospective study

Ramelteon is Not Associated With Improved Outcomes Among Critically Ill Delirious Patients: A Single-Center Retrospective Cohort Study. Thom, R. Bui, M. Rosner, B. Teslyar, P. Levy-Carrick, N. Wolfe, D. Klompas, M. Psychosomatics 2018

Delirium
Melatonin
Mortality
Ramelteon
Ventilation

A daily multidisciplinary assessment of older adults undergoing elective colorectal cancer surgery is associated with reduced delirium and geriatric syndromes. Tarazona-Santabalbina, F. J. Llabata-Broseta, J. Belenguer-Varea, A. Alvarez-Martinez, D. Cuesta-Peredo, D. Avellana-Zaragoza, J. A. J Geriatr Oncol 2018

Colorectal surgery
Delirium
Frail
Geriatric assessment
Older patients

Preventive Effect of Suvorexant for Postoperative Delirium after Coronary Artery Bypass Grafting. Tamura, K. Maruyama, T. Sakurai, S. Ann Thorac Cardiovasc Surg 2018

Suvorexant
coronary artery bypass grafting
orexin receptor antagonist
postoperative delirium

Aproach to the risk of delirium in an orthogeriatric unit. Sopena Bert, E. Qanneta, R. Valenti Moreno, V. San Jose Laporte, A. Med Clin 2018

Delirium
Fractura de cadera
Hip fracture
Orthogeriatrics
Ortogeriatria

A systematic review of the use of music interventions to improve outcomes for patients undergoing hip or knee surgery. Sibanda, A. Carnes, D. Visentin, D. Cleary, M. J Adv Nurs 2018

anxiety
hip surgery
knee surgery
literature review
music interventions
nursing
pain
postoperative delirium

Use of "Months of the Year Backwards" (MOTYB) as a Screening Tool for Delirium in Palliative Care Patients in the Acute Hospital Setting. Ryan, S. Hayes, D. Creedon, B. Ir Med J 2018
Impact of psychotic symptoms on clinical outcomes in delirium. Paik, S. H. Ahn, J. S. Min, S. Park, K. C. Kim, M. H. PLoS ONE 2018

neuroleptic agent
age distribution
aged
article
clinical outcome
comorbidity
controlled study
delirium
Delirium Rating Scale revised 98
delusion
disease classification
disease course
disease severity
female
hospital mortality
human
major clinical study
male
medical record review
patient assessment
perception disorder
psychosis
retrospective study
scoring system
sex difference
thought disorder

Preoperative age and prognostic nutritional index are useful factors for evaluating postoperative delirium among patients with adult spinal deformity. Oe, S. Togawa, D. Yamato, Y. Hasegawa, T. Yoshida, G. Kobayashi, S. Yasuda, T. Banno, T. Arima, H. Mihara, Y. Ushirozako, H. Yamada, T. Matsuyama, Y. Spine 2018
Decreased Risk of Delirium With Use of Regional Analgesia in Geriatric Trauma Patients With Multiple Rib Fractures. O'Connell, K. M. Quistberg, D. A. Tessler, R. Robinson, B. R. H. Cuschieri, J. Maier, R. V. Rivara, F. P. Vavilala, M. S. Bhalla, P. I. Arbabi, S. Ann Surg 2018

OBJECTIVE: The aim of this study was to examine the risk of delirium in geriatric trauma patients with rib fractures treated with systemic opioids compared with those treated with regional analgesia (RA). SUMMARY OF BACKGROUND DATA: Delirium is a modifiable complication associated with increased morbidity and mortality. RA may reduce the need for opioid medications, which are associated with delirium in older adults. METHODS: Cohort study of patients >/=65 years admitted to a regional trauma center from 2011 to 2016. Inclusion factors were >/= 3 rib fractures, blunt trauma mechanism, and admission to intensive care unit (ICU). Exclusion criteria included head AIS >/=3, spine AIS >/=3, dementia, and death within 24 hours. The primary outcome was delirium positive ICU days, defined using the CAM-ICU assessment. Delirium incident rate ratios (IRRs) and 95% confidence intervals (95% CIs) were estimated using generalized linear mixed models with Poisson distribution and robust standard errors. RESULTS: Of the 144 patients included in the study, 27 (19%) received Acute Pain Service consultation and RA and 117 (81%) received opioid-based systemic analgesia. Patients with RA had more severe chest injury than those without. The risk of delirium decreased by 24% per day per patient with use of RA (IRR 0.76, 95% CI 0.61 to 0.96). Individual opioid use, as measured in daily morphine equivalents (MEDs), was significantly reduced after initiation of RA (mean difference -7.62, 95% CI -14.4 to -0.81). CONCLUSION: Although use of RA techniques in geriatric trauma patients with multiple rib fractures was associated with higher MED, opioid use decreased after RA initiation and Acute Pain Service consultation, and the risk of delirium was lower.

Hypotension and a positive fluid balance are associated with delirium in patients with shock. Nguyen, D. N. Huyghens, L. Parra, J. Schiettecatte, J. Smitz, J. Vincent, J. L. PLoS One 2018
End-Tidal Hypocapnia Under Anesthesia Predicts Postoperative Delirium. Mutch, W. A. C. El-Gabalawy, R. Girling, L. Kilborn, K. Jacobsohn, E. Front Neurol 2018

*anesthetic agent
*carbon dioxide
*cognition
*hypercapnia
*hypocapnia
*normocapnia
*postoperative complications
*postoperative delirium

Risk Factors for Delirium after Spine Surgery: An Age-Matched Analysis. Morino, T. Hino, M. Yamaoka, S. Misaki, H. Ogata, T. Imai, H. Miura, H. Asian Spine J 2018

Delirium
Hemorrhage
Multivariate analysis
Risk factors
Spine

Outcomes of Patients With Delirium in Long-Term Care Facilities: A Prospective Cohort Study. Moon, K. J. Park, H. J Gerontol Nurs 2018

Aged
Aged, 80 and over
Cohort Studies
Delirium/*mortality/*nursing
Dementia/*mortality/*nursing
Female
Hospitalization/statistics & numerical data
Humans
Incidence
Long-Term Care/*methods/*statistics & numerical data
Male
Middle Aged
Patient Discharge/statistics & numerical data
Prospective Studies
Republic of Korea
Skilled Nursing Facilities/*statistics & numerical data
Treatment Outcome

Intravenous versus inhalational maintenance of anaesthesia for postoperative cognitive outcomes in elderly people undergoing non-cardiac surgery. Miller, D. Lewis, S. R. Pritchard, M. W. Schofield-Robinson, O. J. Shelton, C. L. Alderson, P. Smith, A. F. Cochrane Database of Systematic Reviews 2018

Aged
Anesthesia, Inhalation
Anesthesia, Intravenous
Anesthetics, Inhalation
Anesthetics, Intravenous/*adverse effects
Cognition/*drug effects
Cognition Disorders/chemically induced
Delirium/chemically induced
Desflurane
Humans
Hypotension/chemically induced
Isoflurane/adverse effects/analogs & derivatives
Methyl Ethers/adverse effects
Middle Aged
Postoperative Complications/chemically induced/mortality
Propofol/*adverse effects
Randomized Controlled Trials as Topic
Sevoflurane
*Surgical Procedures, Operative

Incidence, risk factors and clinical impact of postoperative delirium following open reduction and internal fixation (ORIF) for hip fractures: an analysis of 7859 patients from the ACS-NSQIP hip fracture procedure targeted database. Malik, A. T. Quatman, C. E. Phieffer, L. S. Ly, T. V. Khan, S. N. Eur J Orthop Surg Traumatol 2018

Delirium
Hip fracture
Nsqip
ORIF delirium
Open reduction internal fixation

Delirium After Cardiac Surgery and Cumulative Fluid Balance: A Case-Control Cohort Study. Mailhot, T. Cossette, S. Lambert, J. Beaubien-Souligny, W. Cournoyer, A. O'Meara, E. Maheu-Cadotte, M. A. Fontaine, G. Bouchard, J. Lamarche, Y. Benkreira, A. Rochon, A. Denault, A. J Cardiothorac Vasc Anesth 2019

cardiac surgery
cardiology
cohort study
critical care
delirium
fluid balance

The point-of-care EEG for delirium detection in the emergency department. Lee, S. Yuki, K. Chan, A. Cromwell, J. Shinozaki, G. Am J Emerg Med 2018

Bispectral EEG
Delirium
Power spectral density analysis

Intraoperative hypotension is not associated with postoperative cognitive dysfunction in elderly patients undergoing general anesthesia for surgery: results of a randomized controlled pilot trial. Langer, T. Santini, A. Zadek, F. Chiodi, M. Pugni, P. Cordolcini, V. Bonanomi, B. Rosini, F. Marcucci, M. Valenza, F. Marenghi, C. Inglese, S. Pesenti, A. Gattinoni, L. J Clin Anesth 2019

Anesthesia, general
Blood pressure
Cognitive dysfunction
Delirium
Frail elderly

Differences in healthcare outcomes between teaching and non teaching hospitals for patients with delirium: a retrospective cohort study. Kotwal, S. Abougergi, M. S. Wright, S. Int J Qual Health Care 2018
Gender differences in the use of atypical antipsychotic medications for ICU delirium. Karamchandani, K. Schoaps, R. S. Printz, J. Kowaleski, J. M. Carr, Z. J. Crit Care 2018
Whole-Genome mRNA Gene Expression Differs Between Patients With and Without Delirium. Kalantar, K. LaHue, S. C. DeRisi, J. L. Sample, H. A. Contag, C. A. Josephson, S. A. Wilson, M. R. Douglas, V. C. Journal of Geriatric Psychiatry and Neurology 2018

integrin
interleukin 6
interleukin 8
messenger RNA
paxillin
actin filament
aged
article
case control study
clinical article
cognition
complement system
controlled study
delirium
female
gene expression
genetic code
glioma
human
male
peripheral blood mononuclear cell
priority journal
prospective study
protein expression
quality control
RNA sequence
sequence alignment
systemic inflammatory response syndrome
transcription regulation
upregulation
urinary tract infection
whole genome sequencing

Incidence and risk factors of subsyndromal delirium after curative resection of gastric cancer. Hwang, H. Lee, K. M. Son, K. L. Jung, D. Kim, W. H. Lee, J. Y. Kong, S. H. Suh, Y. S. Lee, H. J. Yang, H. K. Hahm, B. J. BMC Cancer 2018

adult
age
aged
anesthesia
anxiety disorder
article
cancer surgery
cognition
delirium
depression
educational status
female
gastrectomy
human
incidence
major clinical study
male
postoperative complication
risk assessment
risk factor
sleep quality
stomach cancer
subsyndromal delirium

Performance of Electronic Prediction Rules for Prevalent Delirium at Hospital Admission. Halladay, C. W. Sillner, A. Y. Rudolph, J. L. JAMA Netw Open 2018
Harmonization of delirium severity instruments: a comparison of the DRS-R-98, MDAS, and CAM-S using item response theory. Gross, A. L. Tommet, D. D'Aquila, M. Schmitt, E. Marcantonio, E. R. Helfand, B. Inouye, S. K. Jones, R. N. BMC Med Res Methodol 2018

Delirium
Elderly
Item response theory
Psychometrics
Severity

Prognostic factors of inhospital death in elderly patients: A time-to-event analysis of a cohort study in Martinique (French West Indies). Godaert, L. Bartholet, S. Dorléans, F. Najioullah, F. Colas, S. Fanon, J. L. Cabié, A. Césaire, R. Dramé, M. BMJ Open 2018

aged
alcoholism
area under the curve
article
bootstrapping
cardiovascular disease
Charlson Comorbidity Index
chikungunya
cohort analysis
confusion
delirium
female
hospital admission
hospital mortality
hospitalization
human
internal validity
kidney failure
longitudinal study
major clinical study
male
Martinique
musculoskeletal pain
prediction
prognosis
proportional hazards model
receiver operating characteristic
respiratory tract infection
retrospective study
reverse transcription polymerase chain reaction
sensitivity and specificity
very elderly

The Critical Vital Sign of Cognitive Health and Delirium: Whose Responsibility Is It? Fick, D. M. J Gerontol Nurs 2018
Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU. Devlin, J. W. Skrobik, Y. Gelinas, C. Needham, D. M. Slooter, A. J. C. Pandharipande, P. P. Watson, P. L. Weinhouse, G. L. Nunnally, M. E. Rochwerg, B. Balas, M. C. van den Boogaard, M. Bosma, K. J. Brummel, N. E. Chanques, G. Denehy, L. Drouot, X. Fraser Crit Care Med 2018
Delirium etiology subtypes and their effect on six-month function and cognition in older emergency department patients. Cirbus, J. MacLullich, A. M. J. Noel, C. Ely, E. W. Chandrasekhar, R. Han, J. H. International Psychogeriatrics 2018

aged
article
central nervous system
checklist
cognitive defect
cohort analysis
controlled study
daily life activity
emergency ward
female
functional status
hospital patient
human
major clinical study
male
metabolic disorder
multiple linear regression analysis
outcome assessment
physician
prospective study
questionnaire
tertiary health care
university hospital

Perioperative Sedation in Mechanically Ventilated Cardiac Surgery Patients With Dexmedetomidine-Based Versus Propofol-Based Regimens. Chuich, T. Cropsey, C. L. Shi, Y. Johnson, D. Shotwell, M. S. Henson, C. P. Ann Pharmacother 2019

anesthesia
cardiology
critical care

Hospital discharge data under-reports delirium occurrence. Results from a point prevalence survey of delirium in a major Australian health service. Casey, P. Cross, W. Webb-St Mart, M. Baldwin, C. Riddell, K. Darzins, P. Intern Med J 2018

Adult
Delirium
International Classification of Diseases
Mental Status and Dementia Tests
Prevalence

TIME to think about delirium: improving detection and management on the acute medical unit. Bauernfreund, Y. Butler, M. Ragavan, S. Sampson, E. L. BMJ Open Qual 2018

Pdsa
hospital medicine
medical education
mental health
quality improvement

The Association of Delirium with Perioperative Complications in Primary Elective Total Hip Arthroplasty. Aziz, K. T. Best, M. J. Naseer, Z. Skolasky, R. L. Ponnusamy, K. E. Sterling, R. S. Khanuja, H. S. Clin Orthop Surg 2018

Aged
*Arthroplasty, Replacement, Hip/adverse effects/statistics & numerical data
Delirium/*complications/*epidemiology
Elective Surgical Procedures/adverse effects/statistics & numerical data
Female
Humans
Intraoperative Complications/*epidemiology
Male
Middle Aged
Postoperative Complications/*epidemiology
Retrospective Studies
Delirium
Hip arthroplasty
Postoperative complications
Preoperative complications
was reported.

Bispectral Index Monitoring During Anesthesia Promotes Early Postoperative Recovery of Cognitive Function and Reduces Acute Delirium in Elderly Patients with Colon Carcinoma: A Prospective Controlled Study using the Attention Network Test. Zhou, Y. Li, Y. Wang, K. Med Sci Monit 2018

Aged
Anesthesia, General/methods
Anesthesiology
Anesthetics, Intravenous/administration & dosage
Attention/drug effects/physiology
Cognition/drug effects
Colonic Neoplasms/complications
Consciousness Monitors
Delirium/*prevention & control
Executive Function/drug effects
Female
Humans
Male
Monitoring, Intraoperative/*methods
Postoperative Care
Postoperative Complications/*prevention & control
Postoperative Period
Prospective Studies

Military Service Members and Emergence Delirium Screening: An Evidence-Based Practice Project. Wheat, L. L., 2nd Turner, B. S. Diaz, A. Maani, C. V. J Perianesth Nurs 2018

emergence delirium
emergence delirium screening
preanesthesia screening
preoperative
quality improvement

Can delirium research activity impact on routine delirium recognition? A prospective cohort study. Welch, C. Jackson, T. A. BMJ Open 2018

dementia

Preoperative STOP-BANG Scores and Postoperative Delirium and Coma in Thoracic Surgery Patients. Wang, S. Sigua, N. L. Manchanda, S. Gradney, S. Khan, S. H. Perkins, A. Kesler, K. Khan, B. Ann Thorac Surg 2018
The Cost of ICU Delirium and Coma in the Intensive Care Unit Patient. Vasilevskis, E. E. Chandrasekhar, R. Holtze, C. H. Graves, J. Speroff, T. Girard, T. D. Patel, M. B. Hughes, C. G. Cao, A. Pandharipande, P. P. Ely, E. W. Med Care 2018
Pharmacologic prevention of postoperative delirium after on-pump cardiac surgery: A meta-analysis of randomized trials. Tao, R. Wang, X. W. Pang, L. J. Cheng, J. Wang, Y. M. Gao, G. Q. Liu, Y. Wang, C. Medicine 2018

Antipsychotic Agents/*therapeutic use
Cardiac Surgical Procedures/*adverse effects
Delirium/etiology/*prevention & control
Humans
Postoperative Complications/etiology/*prevention & control
*Randomized Controlled Trials as Topic

Epigenetics of Delirium and Aging: Potential Role of DNA Methylation Change on Cytokine Genes in Glia and Blood Along With Aging. Shinozaki, G. Braun, P. R. Hing, B. W. Q. Ratanatharathorn, A. Klisares, M. J. Duncan, G. N. Jellison, S. S. Heinzman, J. T. Nagahama, Y. Close, L. Sabbagh, S. Dlouhy, B. J. Howard, M. A. Kawasaki, H. Cho, H. R. Front Aging Neurosci 2018

DNA methylation
aging
cytokine
delirium
epigenetics
tNF-alpha

The Hospital Elder Life Program: Past and Future. Scheunemann, L. P. Girard, T. D. Skidmore, E. R. Resnick, N. M. Am J Geriatr Psychiatry 2018
Delirium in the Acute Phase of Ischemic Stroke: Incidence, Risk Factors, and Effects on Functional Outcome. Qu, J. Chen, Y. Luo, G. Zhong, H. Xiao, W. Yin, H. J Stroke Cerebrovasc Dis 2018

Activities of Daily Living
Aged
Brain Ischemia/diagnosis/*epidemiology/physiopathology/psychology
China/epidemiology
Delirium/diagnosis/*epidemiology/physiopathology/psychology
Diffusion Magnetic Resonance Imaging
Disability Evaluation
Female
Health Status
Humans
Incidence
Male
Middle Aged
Neuropsychological Tests
Prognosis
Prospective Studies
Recovery of Function
Risk Factors
Severity of Illness Index
Stroke/diagnosis/*epidemiology/physiopathology/psychology
Time Factors
Delirium
Mri
functional status
ischemic stroke
psychiatric symptoms

Effect of dynamic light at the coronary care unit on the length of hospital stay and development of delirium: A retrospective cohort study. Pustjens, T. Schoutens, A. M. C. Janssen, L. Heesen, W. F. Journal of Geriatric Cardiology 2018

neuroleptic agent
tranquilizer
adult
age
aged
article
cardiac patient
circadian rhythm
clinical effectiveness
clinical outcome
cohort analysis
consultation
controlled study
coronary care unit
delirium
evaluation study
female
fluorescent lighting
geriatric care
geriatrician
hospitalization
human
illumination
incidence
length of stay
major clinical study
male
observational study
outcome assessment
phototherapy
prescription
retrospective study
risk factor
risk reduction

Frailty and Delirium in Older Adults: A Systematic Review and Meta-Analysis of the Literature. Persico, I. Cesari, M. Morandi, A. Haas, J. Mazzola, P. Zambon, A. Annoni, G. Bellelli, G. J Am Geriatr Soc 2018

cognition
delirium
frailty
geriatric assessment
review

Medications and Patient Characteristics Associated With Falling in the Hospital. OʼNeil, C. A. Krauss, M. J. Bettale, J. Kessels, A. Costantinou, E. Dunagan, W. C. Fraser, V. J. Journal of Patient Safety 2018

adult
article
case control study
clinical evaluation
controlled study
dizziness
fall risk
female
human
incontinence
major clinical study
muscle
obesity
randomized controlled trial
risk assessment
risk factor
tertiary care center
underweight
anticonvulsive agent
haloperidol
insulin
proton pump inhibitor
tricyclic antidepressant agent

Delirium detection using relative delta power based on 1-minute single-channel EEG: a multicentre study. Numan, T. van den Boogaard, M. Kamper, A. M. Rood, P. J. T. Peelen, L. M. Slooter, A. J. C. Br J Anaesth 2018

complications, postoperative
delirium
electroencephalography
intensive care unit
monitoring
postoperative care

Low skeletal muscle mass as a risk factor for postoperative delirium in elderly patients undergoing colorectal cancer surgery. Mosk, C. A. L. A. van Vugt J de Jonge, H. Witjes, C. D. Buettner, S. Ijzermans, J. N. van der Laan, L. Clin Interv Aging 2018

Aged
Aged, 80 and over
Cohort Studies
Colorectal Neoplasms/*surgery
Correlation of Data
Delirium/epidemiology/*etiology
Disability Evaluation
Female
Humans
Male
*Muscle Strength
Netherlands
Postoperative Complications/*etiology
Protein-Energy Malnutrition/complications/epidemiology
Retrospective Studies
Risk Factors
Sarcopenia/*complications/epidemiology
*colorectal surgery
*elderly
*nomogram
*postoperative delirium
*sarcopenia
*skeletal muscle mass

Symptom expression in advanced cancer patients admitted to hospice or home care with and without delirium. Mercadante, S. Masedu, F. Maltoni, M. De Giovanni, D. Montanari, L. Pittureri, C. Berte, R. Russo, D. Ursini, L. Marinangeli, F. Aielli, F. Intern Emerg Med 2018

Advanced cancer
Delirium
Edmonton Symptom Assessment Scale
Memorial Delirium Assessment Scale
Palliative care

Symptom Expression in Patients with Advanced Cancer Admitted to an Acute Supportive/Palliative Care Unit With and Without Delirium. Mercadante, S. Adile, C. Ferrera, P. Cortegiani, A. Casuccio, A. Oncologist 2018

Advanced cancer
Delirium
Edmonton Symptom Assessment Scale
Memorial Delirium Assessment Scale
Palliative care
article.

Pain, agitation and delirium assessment and management in a community medical-surgical ICU: results from a prospective observational study and nurse survey. Maximous, R. Miller, F. Tan, C. Camargo, M. Ross, K. Marshall, C. Yung, P. Fleming, D. Law, M. Tsang, J. L. Y. BMJ Open Qual 2018

attitudes
critical care
nurses
performance measures

Evaluating the risk profile of quetiapine in treating delirium in the intensive care adult population: A retrospective review. Mangan, K. C. McKinzie, B. P. Deloney, L. P. Leon, S. M. Eriksson, E. A. J Crit Care 2018

Delirium
QTc prolongation
Quetiapine

Cerebral monitoring of anaesthesia on reducing cognitive dysfunction and postoperative delirium: a systematic review. Luo, C. Zou, W. J Int Med Res 2018

Anesthesia/*adverse effects/methods
Cognitive Dysfunction/etiology/*prevention & control
Delirium/etiology/*prevention & control
Electroencephalography
Humans
*Intraoperative Neurophysiological Monitoring/methods
Postoperative Complications/etiology/prevention & control
Randomized Controlled Trials as Topic
Cerebral monitoring
anaesthesia
cognitive dysfunction
meta-analysis
postoperative delirium
systematic review

Dysfunctional cerebral autoregulation is associated with delirium in critically ill adults. Lee, K. F. Wood, M. D. Maslove, D. M. Muscedere, J. G. Boyd, J. G. J Cereb Blood Flow Metab 2018

Cerebral autoregulation
cerebral oximetry
critical illness
delirium
near-infrared spectroscopy

Defining delirium in idiopathic Parkinson's disease: A systematic review. Lawson, R. A. McDonald, C. Burn, D. J. Parkinsonism and Related Disorders 2018

adult
adverse outcome
article
delirium
diagnosis
female
hospital patient
hospitalization
human
male
motor dysfunction
Parkinson disease
prevalence
prospective study
risk factor
systematic review

Delirium assessment in neuro-critically ill patients: A validation study. Larsen, L. K. Frokjaer, V. G. Nielsen, J. S. Skrobik, Y. Winkler, Y. Moller, K. Petersen, M. Egerod, I. Acta Anaesthesiol Scand 2018

acute brain injury
confusion assessment method for the ICU
delirium
intensive care delirium screening checklist
international classification of diseases-10
neurointensive care unit

Benzodiazepine Use and Neuropsychiatric Outcomes in the ICU: A Systematic Review Kok, L. Slooter, A. J. Hillegers, M. H. van Dijk, D. Veldhuijzen, D. S. Crit Care Med 2018
Hospital Elder Life Program: Systematic Review and Meta-analysis of Effectiveness Hshieh, T. T. Yang, T. Gartaganis, S. L. Yue, J. Inouye, S. K. Am J Geriatr Psychiatry 2018

Delirium prevention
Hospital Elder Life Program
multicomponent nonpharmacological intervention

Predictive Modeling for Geriatric Hip Fracture Patients: Early Surgery and Delirium Have the Largest Influence on Length of Stay. Hecht, G. Slee, C. A. Goodell, P. B. Taylor, S. L. Wolinsky, P. R. J Am Acad Orthop Surg 2018
The Erasmus Frailty Score is associated with delirium and 1-year mortality after Transcatheter Aortic Valve Implantation in older patients. The TAVI Care & Cure program. Goudzwaard, J. A. de Ronde-Tillmans, Mjag El Faquir, N. Acar, F. Van Mieghem, N. M. Lenzen, M. J. de Jaegere, P. P. T. Mattace-Raso, F. U. S. Int J Cardiol 2019

Delirium
Erasmus Frailty Score
Frailty
Mortality
Prognosis
Transcatheter Aortic Valve Implantation

Transcutaneous electrical acupoint stimulation for prevention of postoperative delirium in geriatric patients with silent lacunar infarction: a preliminary study. Gao, F. Zhang, Q. Li, Y. Tai, Y. Xin, X. Wang, X. Wang, Q. Clin Interv Aging 2018

*Acupuncture Points
Aged
Blood-Brain Barrier/physiology
Delirium/physiopathology/*prevention & control
Female
Finland
Humans
Inflammation Mediators/blood
Male
Middle Aged
Neurologic Examination
Postoperative Complications/physiopathology/*prevention & control
Preoperative Care
Risk Factors
Stroke, Lacunar/*complications/physiopathology
Transcutaneous Electric Nerve Stimulation/*methods
blood-brain barrier
delirium
geriatric
lacunar infarction
neuroinflammation
transcutaneous electrical acupoint stimulation

Dexmedetomidine in prevention and treatment of postoperative and intensive care unit delirium: a systematic review and meta-analysis. Flükiger, J. Hollinger, A. Speich, B. Meier, V. Tontsch, J. Zehnder, T. Siegemund, M. Annals of Intensive Care 2018

dexmedetomidine
haloperidol
midazolam
placebo
article
bradycardia
clinical outcome
Cochrane Library
drug use
human
hypertension
hypotension
Medline
meta analysis
mortality
postoperative delirium
priority journal
randomized controlled trial (topic)
systematic review

Long-term prognostic value of delirium in elderly patients with acute cardiac diseases admitted to two cardiac intensive care units: a prospective study (DELIRIUM CORDIS). Falsini, G. Grotti, S. Porto, I. Toccafondi, G. Fraticelli, A. Angioli, P. Ducci, K. Liistro, F. Pieroni, M. Taddei, T. Romanelli, S. Rossi, R. Bolognese, L. Eur Heart J Acute Cardiovasc Care 2018

Acute Disease
Aged
Aged, 80 and over
Delirium/epidemiology/*etiology
Female
Heart Diseases/*complications/mortality
Humans
Incidence
Intensive Care Units/*statistics & numerical data
Italy/epidemiology
Length of Stay/trends
Male
Prevalence
Prognosis
Prospective Studies
*Risk Assessment
Risk Factors
Survival Rate/trends
Delirium
cardiac intensive care unit
confusion assessment method
elderly
mortality

Persistent Delirium in Elderly patients Three Months After Hospital Discharge from a University Clinic. Constaín, G. A. Ocampo Saldarriaga, M. V. Velásquez Tirado, J. D. Rodríguez-Gázquez, M. D. L. Á Betancur Morales, L. M. Rico Escobar, J. J. Castilla Agudelo, G. A. Maya Osorno, A. F. Revista Colombiana de Psiquiatria 2018

aged
article
clinical article
delirium
descriptive research
DSM-5
follow up
hospital discharge
hospitalization
human
longitudinal study
persistent delirium
prevalence

A Web-Based Serious Game on Delirium as an Educational Intervention for Medical Students: Randomized Controlled Trial. Buijs-Spanjers, K. R. Hegge, H. H. Jansen, C. J. Hoogendoorn, E. de Rooij, S. E. JMIR Serious Games 2018

delirium
education
medical students
serious game

Relationship Between Near-Infrared Spectroscopy-Derived Cerebral Oxygenation and Delirium in Critically Ill Patients: A Systematic Review. Bendahan, N. Neal, O. Ross-White, A. Muscedere, J. Boyd, J. G. J Intensive Care Med 2018

Cam-icu
cerebral oxygenation
critical illness
delirium
intensive care unit
near-infrared spectroscopy

Ability of suvorexant to prevent delirium in patients in the intensive care unit: a randomized controlled trial. Azuma, K. Takaesu, Y. Soeda, H. Iguchi, A. Uchida, K. Ohta, S. Mishima, S. Inoue, T. Inoue, Y. Oda, J. Acute Med Surg 2018

Delirium
intensive care unit
prevention
suvorexant

Incidence of postoperative delirium in elderly ambulatory patients: A prospective evaluation using the FAM-CAM instrument. Aya, A. G. M. Pouchain, P. H. Thomas, H. Ripart, J. Cuvillon, P. J Clin Anesth 2018

Ambulatory surgery
Elderly
Fam-cam
Postoperative delirium

Potential Role of Exogenous Melatonin Supplement in Delirium Prevention in Critically Ill Patients: A Double-Blind Randomized Pilot Study. Abbasi, S. Farsaei, S. Ghasemi, D. Mansourian, M. Iran J Pharm Res 2018

Clinical trial
Critical care
Delirium
Melatonin

Predictive nomogram for postoperative delirium in elderly patients with a hip fracture. Zhang, X. Tong, D. K. Ji, F. Duan, X. Z. Liu, P. Z. Qin, S. Xu, K. H. Di-li, X. T. Injury 2018

aged
article
calibration
cognitive defect
comorbidity
controlled study
erythrocyte
female
femoral neck fracture
human
human cell
intensive care
major clinical study
male
nomogram
postoperative delirium
prevention
probability
retrospective study
risk assessment
risk factor
surgery

Advances in dementia with Lewy bodies Armstrong, M. J. Ther Adv Neurol Disord 2021

Lewy body dementia
Lewy body disease [MeSH]
dementia with Lewy bodies

Factors Influencing CAM-ICU Documentation and Inappropriate "Unable to Assess" Responses Awan, O. M. Buhr, R. G. Kamdar, B. B. Am J Crit Care 2021

Aged, 80 and over
*Delirium/diagnosis
Documentation
Humans
Intensive Care Units
*Nursing Care
Restraint, Physical

Prediction of Postictal Delirium Following Status Epilepticus in the ICU: First Insights of an Observational Cohort Study Baumann, S. M. Semmlack, S. Hunziker, S. Kaplan, P. W. De Marchis, G. M. Rüegg, S. Marsch, S. Sutter, R. Crit Care Med 2021

Aged
Benzodiazepines/administration & dosage
Cohort Studies
Delirium/*diagnosis/epidemiology
Female
Humans
Intensive Care Units/organization & administration/statistics & numerical data
Male
Mass Screening/methods/statistics & numerical data
Middle Aged
Proportional Hazards Models
Retrospective Studies
Risk Factors
Seizures/complications/epidemiology
Severity of Illness Index

Dementia as a predictor of morbidity and mortality in patients with delirium. van Roessel, S. Keijsers, C. J. P. W. Romijn, M. D. M. Maturitas 2019

advance care planning
Barthel index
caregiver
cognition
daily life activity
delirium
dementia
deterioration
functional status
hospital patient
human
Mini Mental State Examination
morbidity
mortality
mortality rate
review
risk factor

Factors Associated With Delirium Following Electroconvulsive Therapy: A Systematic Review. Tsujii, T. Uchida, T. Suzuki, T. Mimura, M. Hirano, J. Uchida, H. J Ect 2019
Predictors of delirium after cardiac surgery in patients with sleep-disordered breathing. Tafelmeier, M. Knapp, M. Lebek, S. Floerchinger, B. Camboni, D. Creutzenberg, M. Wittmann, S. Zeman, F. Schmid, C. Maier, L. S. Wagner, S. Arzt, M. Eur Respir J 2019
The trajectory of C-reactive protein serum levels in older hip fracture patients with postoperative delirium. Slor, C. J. Witlox, J. Adamis, D. Jansen, Rwmm Houdijk, A. P. J. van Gool, W. A. de Jonghe, J. F. M. Eikelenboom, P. Int J Geriatr Psychiatry 2019

C-reactive protein
hip surgery
inflammation
postoperative delirium

Risk Factors for Postoperative Delirium in Type A Aortic Dissection Patients: A Retrospective Study. Shi, Q. Mu, X. Zhang, C. Wang, S. Hong, L. Chen, X. Med Sci Monit 2019
Cortical and subcortical changes in resting-state functional connectivity before and during an episode of postoperative delirium. Oh, J. Shin, J. E. Yang, K. H. Kyeong, S. Lee, W. S. Chung, T. S. Kim, J. J. Aust N Z J Pschiatry 2019

Postoperative delirium
central executive network
default mode network
resting-state functional connectivity
salience network
subcortical abnormality

Association of COMT Val(158)Met Polymorphism With Delirium Risk and Outcomes After Traumatic Brain Injury. Nekrosius, D. Kaminskaite, M. Jokubka, R. Pranckeviciene, A. Lideikis, K. Tamasauskas, A. Bunevicius, A. J Neuropsychiatry Clin Neurosci 2019

Delirium
Traumatic Brain Injury

Association of earlier extubation and postoperative delirium after coronary artery bypass grafting. Muller Moran, H. R. Maguire, D. Maguire, D. Kowalski, S. Jacobsohn, E. Mackenzie, S. Grocott, H. Arora, R. C. Journal of Thoracic and Cardiovascular Surgery 2019

adult
adverse event
anesthesia
article
artificial ventilation
comorbidity
controlled study
coronary artery bypass graft
extubation
female
human
major clinical study
male
perioperative period
postoperative delirium
preoperative evaluation
retrospective study
surgery

Delirium, Dementia, and In-Hospital Mortality: The Results From the Italian Delirium Day 2016, A National Multicenter Study. Morandi, A. Di Santo, S. G. Zambon, A. Mazzone, A. Cherubini, A. Mossello, E. Bo, M. Marengoni, A. Bianchetti, A. Cappa, S. Fimognari, F. Antonelli Incalzi, R. Gareri, P. Perticone, F. Campanini, M. Penco, I. Montorsi, M. Di Bari, M. Trabucchi, M. Bellell J Gerontol A Biol Sci Med Sci 2019

Acute hospital
Cognitive impairment
Confusion
Outcomes

Type D personality is a predictor of prolonged acute brain dysfunction (delirium/coma) after cardiovascular surgery. Matsuishi, Y. Shimojo, N. Unoki, T. Sakuramoto, H. Tokunaga, C. Yoshino, Y. Hoshino, H. Ouchi, A. Kawano, S. Sakamoto, H. Hiramatsu, Y. Inoue, Y. BMC Psychol 2019

Aged
Brain/physiopathology
Cardiac Surgical Procedures/*psychology
Cohort Studies
Coma/*etiology
Delirium/diagnosis/*etiology
Depression/diagnosis/etiology
Female
Humans
Japan
Male
Middle Aged
Personality
Pilot Projects
Prevalence
*Type D Personality
Critical care
Delirium
Delirium/coma days
Depression
Intensive care units
Thoracic surgery
Type D personality

Delirium after primary percutaneous coronary intervention in aged individuals with acute ST-segment elevation myocardial infarction: A retrospective study. Li, S. Zhang, X. H. Zhou, G. D. Wang, J. F. Exp Ther Med 2019

ST-segment elevation
delirium
incidence
myocardial infarction
percutaneous coronary intervention
risk factors

Preventing Delirium Takes a Village: Systematic Review and Meta-Analysis of Delirium Preventive Models of Care. Khan, A. Boukrina, O. Oh-Park, M. Flanagan, N. A. Singh, M. Oldham, M. J Hosp Med 2019
Clinical predictors of postoperative delirium, functional status, and mortality in geriatric patients undergoing non-elective surgery for hip fracture. Harris, M. J. Brovman, E. Y. Urman, R. D. J Clin Anesth 2019

Delirium
Dementia
Functional status
Geriatric
Hip fracture
Mortality
Outcomes

Impairments in balance and mobility identify delirium in patients with comorbid dementia. Gual, N. Richardson, S. J. Davis, D. H. J. Bellelli, G. Hasemann, W. Meagher, D. Kreisel, S. H. MacLullich, A. M. J. Cerejeira, J. Inzitari, M. Morandi, A. Int Psychogeriatr 2019

Delirium
Dementia
Diagnosis and Classification
Motor Disorders

Delirium motor subtypes and prognosis in hospitalized geriatric patients - A prospective observational study. Evensen, S. Saltvedt, I. Lydersen, S. Wyller, T. B. Taraldsen, K. Sletvold, O. J Psychosom Res 2019

Dmss
Delirium
Geriatric
Motor subtypes

Delirium risk in non-surgical patients: systematic review of predictive tools. Dylan, F. Byrne, G. Mudge, A. M. Arch Gerontol Geriatr 2019

clinical prediction rule
delirium
systematic review

Pain, Opioid Intake, and Delirium Symptoms in Adults Following Joint Replacement Surgery. Denny, D. L. Lindseth, G. N. West J Nurs Res 2019

joint replacement surgery
older adults
postoperative pain
subsyndromal delirium

Addition of Vitamin B Complex to Prime Solution in Cobalamin-Deficient Patients to Prevent Postoperative Delirium. Demirdas, E. Atilgan, K. The Heart Surgery Forum 2019

vitamin B complex
aged
cardiopulmonary bypass
controlled clinical trial
controlled study
B12 deficiency
delirium
female
human
male
middle aged
postoperative complication
retrospective study
solution and solubility