Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
COVID-19: What do we need to know about ICU delirium during the SARS-CoV-2 pandemic?
Authors
Kotfis, K. Williams Roberson, S. Wilson, J. Pun, B. Ely, E. W. Jeżowska, I. Jezierska, M. Dabrowski, W.
Year
2020
Journal
Anaesthesiol Intensive Ther
Abstract

In March 2020, the World Health Organisation announced the COVID-19 pandemic caused by the SARS-CoV-2 virus. As well as respiratory failure, the SARS-CoV-2 may cause central nervous system (CNS) involvement, including delirium occurring in critically ill patients (ICU delirium). Due attention must be paid to this subject in the face of the COVID-19 pandemic. Delirium, the detection of which takes less than two minutes, is frequently underestimated during daily routine ICU care, but it may be a prodromal symptom of infection or hypoxia associated with severe respiratory failure. During the COVID-19 pandemic, systematic delirium monitoring using validated tests (CAM-ICU or ICDSC) may be sacrificed. This is likely to be due to the fact that the main emphasis is placed on organisational issues, i.e. the lack of ventilators, setting priorities for limited mechanical ventilation options, and a shortage of personal protective equipment. Early identification of patients with delirium is critical in patients with COVID-19 because the occurrence of delirium may be an early symptom of worsening respiratory failure or of infectious spread to the CNS mediated by potential neuroinvasive mechanisms of the coronavirus. The purpose of this review is to identify problems related to the development of delirium during the COVID-19 epidemic, which are presented in three areas: i) factors contributing to delirium in COVID-19, ii) potential pathophysiological factors of delirium in COVID-19, and iii) long-term consequences of delirium in COVID-19. This article discusses how healthcare workers can reduce the burden of delirium by identifying potential risk factors and difficulties during challenges associated with SARS-CoV-2 infection.

PMID

32419438

Keywords

Pics
Ptsd
SARS-CoV-2
coronavirus
delirium
pain
pandemic
sedation
Covid-19

Page(s)
Issue

Search:
Total Records Found: 5897, showing 100 per page
TitleAuthorsJournalYearKeywords
Risk Factors of Postoperative Delirium in the Intensive Care Unit After Liver Transplantation. Lee, H. Oh, S. Y. Yu, J. H. Kim, J. Yoon, S. Ryu, H. G. World J Surg 2018
Risk Factors for Postoperative Delirium After Deep Brain Stimulation Surgery for Parkinson's Disease. Tanaka, M. Tani, N. Maruo, T. Oshino, S. Hosomi, K. Saitoh, Y. Kishima, H. World Neurosurg 2018

Deep Brain Stimulation
Parkinson’s Disease
Postoperative Delirium
Risk Factor

The relationship of delirium and risk factors in cardiology intensive care unit patients with the nursing workload. Ozturk Birge, A. Beduk, T. J Clin Nurs 2018

Critical Care
Intensive Care
Management
Medical Nursing
Nursing
Risk Assessment

Protocol for a single-centre prospective observational study of postoperative delirium following total joint arthroplasties among South East Asians. Abdullah, H. R. Tan, S. R. Lee, S. J. Bin Abd Razak, H. R. Seet, R. H. Ying, H. Sethi, E. Sim, E. Y. BMJ Open 2018

*delirium
*incidence
*postoperative
*total joint arthroplasty

Preoperative statins are associated with a reduced risk of postoperative delirium following vascular surgery. Lee, D. S. Lee, M. Y. Park, C. M. Kim, D. I. Kim, Y. W. Park, Y. J. PLoS One 2018
Predisposing and precipitating factors for delirium in community-dwelling older adults admitted to hospital with this condition: A prospective case series. Magny, E. Le Petitcorps, H. Pociumban, M. Bouksani-Kacher, Z. Pautas, É Belmin, J. Bastuji-Garin, S. Lafuente-Lafuente, C. PLoS One 2018

aged
article
cognitive defect
community care
dehydration
delirium
disease predisposition
electrolyte disturbance
emergency care
female
geriatric care
geriatrician
hospital admission
human
hyponatremia
lung infection
major clinical study
male
mental health
neurologic disease
patient assessment
personalized medicine
prospective study
urinary tract infection
very elderly

Predicting excess cost for older inpatients with clinical complexity: A retrospective cohort study examining cognition, comorbidities and complications Bail, K. Draper, B. Berry, H. Karmel, R. Goss, J. PLoS One 2018

adult
age
aged
article
Australia
cognition
cohort analysis
comorbidity
decubitus
delirium
dementia
disease severity
female
hospital admission
hospital patient
hospitalization cost
human
length of stay
linear regression analysis
major clinical study
male
nursing care
pneumonia
prediction
public hospital
retrospective study
sex
urinary tract infection

Pilot Study of a Two-Step Delirium Detection Protocol Administered By Certified Nursing Assistants, Physicians, and Registered Nurses. Fick, D. M. Inouye, S. K. McDermott, C. Zhou, W. Ngo, L. Gallagher, J. McDowell, J. Penrod, J. Siuta, J. Covaleski, T. Marcantonio, E. R. J Gerontol Nurs 2018
Perioperative hyperglycaemia and neurocognitive outcome after surgery: a systematic review. Hermanides, J. Qeva, E. Preckel, B. Bilotta, F. Minerva Anestesiol 2018
Low-dose Nocturnal Dexmedetomidine Prevents ICU Delirium: A Randomized, Placebo-controlled Trial. Skrobik, Y. Duprey, M. S. Hill, N. S. Devlin, J. W. Am J Respir Crit Care Med 2018

delirium, sleep, intensive care, dexmedetomidine, randomized controlled trial

Low peripheral levels of insulin growth factor-1 are associated with high incidence of delirium among elderly patients: A systematic review and meta-analysis. Li, D. J. Tseng, P. T. Stubbs, B. Chen, T. Y. Lin, P. Y. Chen, S. L. Thompson, T. Adamis, D. Chu, C. S. Arch Gerontol Geriatr 2018

Biomarker
Delirium
Elderly
Igf-1
Meta-analysis

Is anemia associated with cognitive impairment and delirium among older acute surgical patients? Myint, P. K. Owen, S. McCarthy, K. Pearce, L. Moug, S. J. Stechman, M. J. Hewitt, J. Carter, B. Geriatrics & Gerontology International 2018

anemia
cognitive impairment
delirium
older surgical patients

Intraoperative Sedation With Dexmedetomidine is Superior to Propofol for Elderly Patients Undergoing Hip Arthroplasty: A Prospective Randomized Controlled Study. Mei, B. Meng, G. Xu, G. Cheng, X. Chen, S. Zhang, Y. Zhang, M. Liu, X. Gu, E. Clin J Pain 2018
Infrared pupillometry helps to detect and predict delirium in the post-anesthesia care unit. Yang E, Kreuzer M, Hesse S, Davari P, Lee SC, García PS Journal of clinical monitoring and computing 2017

PLR-200
pupillometer
adult
aged
article
clinical article
confusion assessment method for the intensive care unit score
delirium
female
general anesthesia
human
informed consent
infrared pupillometry
male
observational study
priority journal
prospective study
pupil
pupillometry
receiver operating characteristic
recovery room
scoring system

Influence of Physical Restraint on Delirium of Adult Patients in ICU: A Nested Case-Control Study. Pan, Y. Jiang, Z. Changrong, Y. Wang, L. Zhang, J. Zhou, J. Tao, M. Quan, M. Wu, Q. J Clin Nurs 2018

Delirium
Intensive Care Unit
Nested Case-control Study
Restraint, Physical

Incidence of delirium in the Canadian emergency department and its consequences on hospital length of stay: A prospective observational multicentre cohort study. Émond, M. Boucher, V. Carmichael, P. H. Voyer, P. Pelletier, M. Gouin, É Daoust, R. Berthelot, S. Lamontagne, M. E. Morin, M. Lemire, S. Minh Vu, T. T. Nadeau, A. Rheault, M. Juneau, L. Le Sage, N. Lee, J. BMJ Open 2018

aged
American
article
clinical assessment
cohort analysis
controlled study
crowding (area)
delirium
emergency ward
feedback system
female
functional status
human
incidence
length of stay
major clinical study
male
multicenter study
multivariate analysis
prospective study
telephone interview

Impact of timing and duration of postoperative delirium: a retrospective observational study Lee, H. Ju, J. W. Oh, S. Y. Kim, J. Jung, C. W. Ryu, H. G. Surgery 2018
Frequency and risk factors for subsyndromal delirium in an intensive care unit. Yamada, C. Iwawaki, Y. Harada, K. Fukui, M. Morimoto, M. Yamanaka, R. Intensive Crit Care Nurs 2018

Delirium
Intensive Care Delirium Screening Checklist (ICDSC) scores
Intensive care unit (ICU)
Subsyndromal delirium (SSD)

Focusing on Inattention: The Diagnostic Accuracy of Brief Measures of Inattention for Detecting Delirium. Marra, A. Jackson, J. C. Ely, E. W. Graves, A. J. Schnelle, J. F. Dittus, R. S. Wilson, A. Han, J. H. J Hosp Med 2018
Feasibility of Cognitive Training in Critically Ill Patients: A Pilot Study. Wassenaar, A. Rood, P. Boelen, D. Schoonhoven, L. Pickkers, P. van den Boogaard, M. Am J Crit Care 2018
Evaluation of a sound environment intervention in an ICU: A feasibility study. Johansson, L. Lindahl, B. Knutsson, S. Ogren, M. Persson Waye, K. Ringdal, M. Aust Crit Care 2018

Complex intervention
Feasibility
ICU delirium
Noise
Sound

Effects of Haloperidol on Delirium in Adult Patients: A Systematic Review and Meta-analysis. Shen, Y. Z. Peng, K. Zhang, J. Meng, X. W. Ji, F. Med Princ Pract 2018
The effect of the timing and dose of dexmedetomidine on postoperative delirium in elderly patients after laparoscopic major non-cardiac surgery: A double blind randomized controlled study. Lee, C. Lee, C. H. Lee, G. Lee, J. Hwang, J. J Clin Anesth 2018

Cytokine
Delirium
Dexmedetomidine

Effect of organisational factors on the variation in incidence of delirium in intensive care unit patients: A systematic review and meta-regression analysis. Rood, P. Huisman-de Waal, G. Vermeulen, H. Schoonhoven, L. Pickkers, P. van den Boogaard, M. Aust Crit Care 2018

Critical care
Delirium
Incidence
Meta-analysis
Organisational factors
Systematic review

Effect of Administration of Ramelteon, a Melatonin Receptor Agonist, on the Duration of Stay in the ICU: A Single-Center Randomized Placebo-Controlled Trial. Nishikimi, M. Numaguchi, A. Takahashi, K. Miyagawa, Y. Matsui, K. Higashi, M. Makishi, G. Matsui, S. Matsuda, N. Crit Care Med 2018
Diagnostic accuracy of delirium assessment methods in critical care patients Barman, A. Pradhan, D. Bhattacharyya, P. Dey, S. Bhattacharjee, A. Tesia, S. S. Mitra, J. K. Journal of Critical Care 2018

Acute Physiology and Chronic Health Evaluation II
adult
aged
article
checklist
clinical assessment tool
Confusion Assessment Method for the ICU
controlled study
critically ill patient
delirium
diagnostic accuracy
diagnostic odds ratio
diagnostic test accuracy study
female
human
Intensive Care Delirium Screening Checklist
intensivist
intermethod comparison
interrater reliability
likelihood ratio
major clinical study
male
medical staff
nurse
nursing staff
predictive value
prospective study
psychiatrist
scoring system
sensitivity and specificity
statistical analysis

Delirium in ICU Patients Following Cardiac Surgery: An Observational Study. Simeone, S. Pucciarelli, G. Perrone, M. Rea, T. Gargiulo, G. Guillari, A. Castellano, G. Di Tommaso, L. Niola, M. Iannelli, G. J Clin Nurs 2018

Icu
Cardiosurgery
Patient
delirium
environment
predictors

Clinical phenotypes of delirium during critical illness and severity of subsequent long-term cognitive impairment: a prospective cohort study. Girard, T. D. Thompson, J. L. Pandharipande, P. P. Brummel, N. E. Jackson, J. C. Patel, M. B. Hughes, C. G. Chandrasekhar, R. Pun, B. T. Boehm, L. M. Elstad, M. R. Goodman, R. B. Bernard, G. R. Dittus, R. S. Ely, E. W. Lancet Respir Med 2018
Postoperative Complications Associated With Spine Surgery in Patients Older Than 90 Years: A Multicenter Retrospective Study. Kobayashi, K. Imagama, S. Sato, K. Kato, F. Kanemura, T. Yoshihara, H. Sakai, Y. Shinjo, R. Hachiya, Y. Osawa, Y. Matsubara, Y. Ando, K. Nishida, Y. Ishiguro, N. Global Spine J 2018

complications
elderly patients
multicenter study
older than 90 years
spine surgery
conflicts of interest with respect to the research, authorship, and/or
publication of this article.

Do the Phenotypes of Symptom Fluctuation Differ Among Motor Subtypes in Patients With Delirium?. Kim, S. Y. Kim, J. M. Kim, S. W. Kim, E. S. Kang, H. J. Lee, J. Y. Bae, K. Y. Shin, I. S. Yoon, J. S. J Pain Symptom Manage 2018

Delirium
fluctuation
phenotype
prospective design
subtype

Delirium and its consequences in the specialized palliative care unit: Validation of the Korean version of Memorial Delirium Assessment Scale. Kang, B. Kim, Y. J. Suh, S. W. Son, K. L. Ahn, G. S. Park, H. Y. Psycho-Oncology 2018

adult
advanced cancer
age
alcohol consumption
article
body mass
cancer patient
controlled study
delirium
demography
diagnosis
drowsiness
female
gender
human
internal consistency
major clinical study
male
mortality
oncology
palliative therapy
rating scale
sensitivity and specificity
smoking
symptom assessment
validation process
validity
morphine

The Motoric Types of Delirium and Estimated Blood Loss during Perioperative Period in Orthopedic Elderly Patients. Hong, N. Park, J. Y. Biomed Res Int 2018
CSF sTREM2 in delirium-relation to Alzheimer's disease CSF biomarkers Abeta42, t-tau and p-tau. Henjum, K. Quist-Paulsen, E. Zetterberg, H. Blennow, K. Nilsson, L. N. G. Watne, L. O. J Neuroinflammation 2018

Alzheimer’s disease
CSF biomarkers
Delirium
Dementia
Soluble TREM2

CSF biomarkers in delirium: a systematic review. Hall RJ, Watne LO, Cunningham E, Zetterberg H, Shenkin SD, Wyller TB, MacLullich AMJ International journal of geriatric psychiatry 2017

CSF biomarkers
delirium pathophysiology
neuroinflammation

Prediction of ICU Delirium: Validation of Current Delirium Predictive Models in Routine Clinical Practice. Green, C. Bonavia, W. Toh, C. Tiruvoipati, R. Crit Care Med 2018
The Incidence of Recorded Delirium Episodes Before and After Dementia Diagnosis: Differences Between Dementia With Lewy Bodies and Alzheimer's Disease. FitzGerald, J. M. Perera, G. Chang-Tave, A. Price, A. Rajkumar, A. P. Bhattarai, M. O'Brien, J. T. Ballard, C. Aarsland, D. Stewart, R. Mueller, C. J Am Med Dir Assoc 2018

Alzheimer’s disease
Delirium
dementia
dementia with Lewy bodies
hospitalization

Pain and delirium in people with dementia in the acute general hospital setting. Feast, A. R. White, N. Lord, K. Kupeli, N. Vickerstaff, V. Sampson, E. L. Age Ageing 2018
Environmental factors and risk of delirium in geriatric patients: an observational study. Evensen, S. Saltvedt, I. Lydersen, S. Wyller, T. B. Taraldsen, K. Sletvold, O. BMC Geriatr 2018

Delirium
Environmental
Geriatric patients
Hospital
Risk factors

Validity of a screening method for delirium risk in older patients admitted to a general hospital in the Netherlands. Ettema, R. Heim, N. Hamaker, M. Emmelot-Vonk, M. van der Mast, R. Schuurmans, M. General Hospital Psychiatry 2018

aged
article
calibration
delirium
diagnostic accuracy
diagnostic test accuracy study
female
hospital admission
human
major clinical study
male
Netherlands
predictive value
receiver operating characteristic
retrospective study
risk assessment
screening test
sensitivity and specificity
validity

Indwelling urinary catheters, aortic valve treatment and delirium: a prospective cohort study. Eide, L. S. Ranhoff, A. H. Lauck, S. Fridlund, B. Haaverstad, R. Hufthammer, K. O. Kuiper, K. K. J. Nordrehaug, J. E. Norekval, T. M. BMJ Open 2018

Savr
Tavi
delirium
octogenarian
urinary catheter

Diagnostic value of NT-proCNP compared to NSE and S100B in cerebrospinal fluid and plasma of patients with sepsis-associated encephalopathy. Ehler, J. Saller, T. Wittstock, M. Rommer, P. S. Chappell, D. Zwissler, B. Grossmann, A. Richter, G. Reuter, D. A. Noldge-Schomburg, G. Sauer, M. Neurosci Lett 2018

Biomarker
Encephalopathy
Intensive care unit
Neuroinflammation
Outcome
Sepsis

Exploration of Relationships Between Postoperative Pain and Subsyndromal Delirium in Older Adults. Denny, D. L. Such, T. L. Nurs Res 2018
Prediction of Incident Delirium Using a Random Forest classifier. Corradi, J. P. Thompson, S. Mather, J. F. Waszynski, C. M. Dicks, R. S. J Med Syst 2018

Decision support
Delirium
Machine learning
Prediction
Random forest

The hip fracture surgery in elderly patients (HIPELD) study to evaluate xenon anaesthesia for the prevention of postoperative delirium: a multicentre, randomized clinical trial. Coburn, M. Sanders, R. D. Maze, M. Nguyên-Pascal, M. L. Rex, S. Garrigues, B. Carbonell, J. A. Garcia-Perez, M. L. Stevanovic, A. Kienbaum, P. Neukirchen, M. Schaefer, M. S. Borghi, B. van Oven, H. Tognù, A. Al Tmimi, L. Eyrolle, L. Langeron, O. Capdevi British Journal of Anaesthesia 2018

C reactive protein
sevoflurane
xenon
acute heart infarction
acute kidney failure
aged
anemia
anesthesia level
article
cause of death
controlled study
double blind procedure
female
gastrointestinal disease
general anesthesia
heart disease
heart failure
heart right ventricle failure
hip fracture
hip surgery
human
hypertension
hypotension
length of stay
major clinical study
male
Mini Mental State Examination
multicenter study
multiple organ failure
musculoskeletal disease
neurologic disease
outcome assessment
pain severity
parallel design
phase 2 clinical trial
pneumonia
postoperative delirium
postoperative period
priority journal
protein blood level
randomized controlled trial
respiratory failure
septic shock
Sequential Organ Failure Assessment Score
sex difference
side effect
smoking

Effect of a single pre-operative 125 mg dose of methylprednisolone on postoperative delirium in hip fracture patients; a randomised, double-blind, placebo-controlled trial. Clemmesen, C. G. Lunn, T. H. Kristensen, M. T. Palm, H. Foss, N. B. Anaesthesia 2018

delirium
glucocorticoids
hip fracture

Identifying Patterns of Delirium in Hospitalized Patients on Dexamethasone Using a Chart Abstraction Tool. Chang, J. T. Atayee, R. S. Edmonds, K. P. Journal of Pain and Palliative Care Pharmacotherapy 2018

dexamethasone
adult
agitation
article
assessment of humans
cancer pain
consultation
delirium
disease association
disease severity
Eastern Cooperative Oncology Group Performance
electronic health record
female
functional status
Glasgow coma scale
health care system
hospital admission
hospital patient
human
incidence
major clinical study
male
medical record review
mental health
palliative therapy
retrospective study
Richmond Agitation Sedation Scale

Detecting delirium in elderly medical emergency patients: validation and subsequent modification of the German Nursing Delirium Screening Scale. Brich, J. Baten, V. Wussmann, J. Heupel-Reuter, M. Perlov, E. Kloppel, S. Busch, H. J. Intern Emerg Med 2018

Delirium
Emergency department
Geriatric medicine
Germany
Nu-DESC
Nursing
Validity

Mobilizing older adults: A multi-site, exploratory and observational study on patients enrolled in the Hospital Elder Life Program (HELP). Babine, R. L. Hyrkas, K. E. McKenzie, C. G. Wierman, H. R. Geriatr Nurs 2018

Older adults
falls
hospitalization
mobilization

Validation of the Stanford Proxy Test for Delirium (S-PTD) among critical and noncritical patients. Alosaimi, F. D. Alghamdi, A. Alsuhaibani, R. Alhammad, G. Albatili, A. Albatly, L. Althomali, B. Aljamaan, F. Maldonado, J. R. J Psychosom Res 2018

Delirium
Proxy test for delirium
Screening tools
Validation
sensitivity and specificity

Impact of an Antipsychotic Discontinuation Bundle During Transitions of Care in Critically Ill Patients. D’Angelo, R. G. Rincavage, M. Tata, A. L. Millstein, L. S. Gulati, M. S. Flurie, R. W. Gonzales, J. P. J Intensive Care Med 2019

urinary catheter
haloperidol
lorazepam
morphine
neuroleptic agent
olanzapine
quetiapine
risperidone
ziprasidone
adult
APACHE
article
artificial ventilation
bipolar disorder
cerebrovascular accident
Confusion Assessment Method for intensive care unit
delirium
dementia
depression
disease assessment
drug withdrawal
education
female
hospital discharge
hospitalization
human
hypertension
length of stay
major clinical study
male
medical intensive care unit
middle aged
mortality
Parkinson disease
patient safety
physician
priority journal
retrospective study
risk factor
schizophrenia
transitional care

Living at home after emergency hospital admission: Prospective cohort study in older adults with and without cognitive spectrum disorder. Burton, J. K. Guthrie, B. Hapca, S. M. Cvoro, V. Donnan, P. T. Reynish, E. L. BMC Medicine 2018

aged
article
cognitive spectrum disorder
cohort analysis
controlled study
delirium
dementia
disease association
disorders of higher cerebral function
female
general hospital
geriatric assessment
health service
home care
hospital admission
hospital discharge
hospitalization
human
incidence
major clinical study
male
Older Person Routine Acute Assessment
outcome assessment
prospective study
residential home
risk factor
very elderly

The Association Between C-Reactive Protein and Postoperative Delirium Differs by Catechol-O-Methyltransferase Genotype. Vasunilashorn, S. M. Ngo, L. H. Jones, R. N. Inouye, S. K. Hall, K. T. Gallagher, J. Dillon, S. T. Xie, Z. Libermann, T. A. Marcantonio, E. R. American Journal of Geriatric Psychiatry 2019

acute phase protein
C reactive protein
catechol methyltransferase
DNA
valine
aged
article
cohort analysis
colon resection
controlled study
disease association
DNA extraction
enzyme linked immunosorbent assay
female
genetic association
genotype
human
major clinical study
male
orthopedic surgery
postoperative delirium
prospective study
protein blood level
vascular surgery

Risk factors associated with acute in-hospital delirium for patients diagnosed with a hip fracture in the emergency department. Thompson, C. Brienza, V. J. M. Sandre, A. Caine, S. Borgundvaag, B. McLeod, S. Canadian Journal of Emergency Medicine 2018

codeine
hydromorphone
morphine
oxycodone
paracetamol
adult
age
Alzheimer disease
analgesia
article
atrial fibrillation
breathing rate
cerebrovascular accident
confusion
congestive heart failure
Cushing disease
degenerative disease
delirium
dementia
depression
emergency ward
female
heart rate
hip fracture
hospital patient
human
hypertension
hyperthyroidism
hypothyroidism
length of stay
major clinical study
male
mental health
middle aged
osteoarthritis
osteoporosis
outcome assessment
oxygen saturation
Parkinson disease
retrospective study
risk factor
schizophrenia
systolic blood pressure

A Comparison of Early, Late, and No Treatment of Intensive Care Unit Delirium With Antipsychotics: A Retrospective Cohort Study. Thom, R. P. Bui, M. P. Rosner, B. Teslyar, P. Levy-Carrick, N. C. Klompas, M. The Primary Care Companion for CNS Disorders 2018

neuroleptic agent
coma
comparative study
critical illness
delirium
female
follow up
human
intensive care unit
male
middle aged
mortality
retrospective study
time factor
treatment outcome

Postoperative Pain Management Strategies and Delirium After Transapical Aortic Valve Replacement: A Randomized Controlled Trial. Strike, E. Arklina, B. Stradins, P. Cusimano, R. J. Osten, M. Horlick, E. Styra, R. Poonawala, H. Carroll, J. Djaiani, G. Journal of Cardiothoracic and Vascular Anesthesia 2018

adult
article
clinical article
comorbidity
contraindication
controlled study
dementia
demography
drug therapy
extubation
female
human
intensive care unit
male
morbidity
mortality
opiate addiction
patient controlled analgesia
postoperative delirium
postoperative pain
postoperative period
preoperative evaluation
prospective study
randomization
randomized controlled trial
regional anesthesia
sedation
Sedation Agitation Scale
staff
surgery
tertiary care center
transcatheter aortic valve implantation
university hospital
visual analog scale
local anesthetic agent
opiate

Effect of Depth of Sedation in Older Patients Undergoing Hip Fracture Repair on Postoperative Delirium: The STRIDE Randomized Clinical Trial. Sieber, F. E. Neufeld, K. J. Gottschalk, A. Bigelow, G. E. Oh, E. S. Rosenberg, P. B. Mears, S. C. Stewart, K. J. Ouanes, J. P. P. Jaberi, M. Hasenboehler, E. A. Li, T. Wang, N. Y. JAMA Surg 2018

local anesthetic agent
propofol
aged
anesthesia level
article
Charlson Comorbidity Index
double blind procedure
female
follow up
fracture treatment
hip fracture
hospital discharge
human
incidence
intention to treat analysis
intraoperative period
major clinical study
male
postoperative delirium
postoperative period
priority journal
spinal anesthesia

Incidence of Delirium in Critically Ill Cancer Patients. Sánchez-Hurtado, L. A. Hernández-Sánchez, N. Del Moral-Armengol, M. Guevara-García, H. García-Guillén, F. J. Herrera-Gómez, Á Ñamendys-Silva, S. A. Pain Research & Management 2018

adult
aged
cohort analysis
complication
critical illness
delirium
female
human
incidence
intensive care unit
male
middle aged
neoplasm
risk factor
severity of illness index

Dispersion in Scores on the Richmond Agitation and Sedation Scale as a Measure of Delirium in Patients with Subdural Hematomas. Robinson, D. Thompson, S. Bauerschmidt, A. Melmed, K. Couch, C. Park, S. Agarwal, S. Roh, D. Connolly, E. S. Claassen, J. Neurocritical Care 2018

adult
agitation
APACHE
article
cohort analysis
controlled study
delirium
diagnosis
female
functional disease
human
infection
major clinical study
male
monitoring
neurological intensive care unit
prospective study
Rankin scale
sedation
subdural hematoma
traumatic brain injury

Underdiagnosis of delirium in the elderly in acute care hospital settings: lessons not learned. Ritter, S. R. F. Cardoso, A. F. Lins, M. M. P. Zoccoli, T. L. V. Freitas, M. P. D. Camargos, E. F. Psychogeriatrics 2018

aged
article
bacterial infection
Brazil
cerebrovascular accident
Confusion Assessment Method
controlled study
cross-sectional study
delirium
dementia
diagnostic accuracy
diagnostic error
diagnostic test accuracy study
female
gender
hospital emergency service
human
intermethod comparison
major clinical study
male
mental disease assessment
physician
prevalence
priority journal
self concept
sensitivity and specificity
subjective assessment
underdiagnosis

Risk Factors and Hospital Mortality in Surgical and Non-surgical Patients with Delirium. Restrepo, D. Duque, M. Montoya, L. Berrouet, M. C. Rojas, M. Lopera, G. Giraldo, K. Revista Colombiana de Psiquiatria 2018

cholinergic receptor blocking agent
adult
article
cognitive defect
cohort analysis
delirium
descriptive research
female
hospital mortality
hospital patient
human
major clinical study
male
mortality risk
retrospective study
risk assessment
scientific literature
surgical patient

Caring for Critically Ill Patients with the ABCDEF Bundle: Results of the ICU Liberation Collaborative in Over 15,000 Adults. Pun, B. T. Balas, M. C. Barnes-Daly, M. A. Thompson, J. L. Aldrich, J. M. Barr, J. Byrum, D. Carson, S. S. Devlin, J. W. Engel, H. J. Esbrook, C. L. Hargett, K. D. Harmon, L. Hielsberg, C. Jackson, J. C. Kelly, T. L. Kumar, V. Millner, L. Morse, A. Perme, Crit Care Med 2019

adult
article
artificial ventilation
clinical outcome
cohort analysis
coma
controlled study
critically ill patient
death
delirium
dose response
female
hospital discharge
hospital readmission
human
major clinical study
male
mortality
multicenter study
pain
prospective study
total quality management

Effects of Perioperative Dexmedetomidine on Postoperative Mortality and Morbidity: A Systematic Review and Meta-analysis Peng, K. Ji, F. H. Liu, H. Y. Zhang, J. Chen, Q. C. Jiang, Y. H. Clinical Therapeutics 2018

adult
article
artificial ventilation
atrial fibrillation
bradycardia
cohort analysis
complication
controlled study
delirium
drug therapy
Embase
female
heart arrest
heart surgery
hospitalization
human
intensive care unit
male
Medline
morbidity
outcome assessment
prescription
prevalence
randomized controlled trial (topic)
surgery
surgical mortality
systematic review
dexmedetomidine

Relation Between Delirium and Anticholinergic Drug Burden in a Cohort of Hospitalized Older Patients: An Observational Study. Pasina, L. Colzani, L. Cortesi, L. Tettamanti, M. Zambon, A. Nobili, A. Mazzone, A. Mazzola, P. Annoni, G. Bellelli, G. Drugs Aging 2018

adverse event
aged
animal experiment
animal model
animal tissue
anticholinergic effect
article
central nervous system
cohort analysis
controlled study
cross-sectional study
delirium
dementia
diagnosis
dose response
drug combination
drug therapy
drug toxicity
female
Italy
male
malnutrition
multicenter study
nonhuman
nutritional assessment
observational study
retrospective study
risk assessment
sensitivity and specificity
side effect
univariate analysis
cholinergic receptor blocking agent
quetiapine

Neopterin and mini-mental state examination scores, two independent risk factors for postoperative delirium in elderly patients with open abdominal surgery. Miao, S. Shen, P. Zhang, Q. Wang, H. Shen, J. Wang, G. Lv, D. Journal of Cancer Research and Therapeutics 2018

C reactive protein
interleukin 6
neopterin
somatomedin C
abdominal surgery
aged
article
blood sampling
body mass
cancer research
cancer surgery
Charlson Comorbidity Index
comorbidity
comparative study
delirium
DSM-IV
enzyme linked immunosorbent assay
female
gastrointestinal tumor
geriatric patient
human
laparotomy
logistic regression analysis
major clinical study
male
mental health
Mini Mental State Examination
open surgery
postoperative delirium
prediction
risk factor

Reliability and accuracy of delirium assessments among investigators at multiple international centres. Maybrier, H. R. Mickle, A. M. Escallier, K. E. Lin, N. Schmitt, E. M. Upadhyayula, R. T. Wildes, T. S. Mashour, G. A. Palihnich, K. Inouye, S. K. Avidan, M. S. BMJ Open 2018

NCT01690988
aged
article
clinical article
controlled study
delirium
diagnostic accuracy
disease severity
feedback system
female
human
interrater reliability
male
multicenter study
outcome assessment
predictive value
prophylaxis
randomized controlled trial
sensitivity and specificity
videorecording

Does the melatonin receptor 1B gene polymorphism have a role in postoperative delirium? Mahanna-Gabrielli, E. Miano, T. A. Augoustides, J. G. Kim, C. Bavaria, J. E. Andrew Kofke, W. PLoS ONE 2018

adult
aged
aortic root surgery
aortic valve repair
article
controlled study
female
genetic risk
genotype
human
major clinical study
male
melatonin receptor 1B gene
postoperative delirium
receptor gene
single nucleotide polymorphism

Volatile anaesthetics and postoperative delirium in older surgical patients—A secondary analysis of prospective cohort studies Kinjo, S. Lim, E. Magsaysay, M. V. Sands, L. P. Leung, J. M. Acta Anaesthesiol Scand 2019

desflurane
isoflurane
sevoflurane
aged
article
brain function
cognition
cohort analysis
controlled study
drug efficacy
drug safety
female
follow up
human
incidence
major clinical study
male
peripheral nerve
postoperative delirium
postoperative pain
preoperative evaluation
priority journal
prospective study
secondary analysis
surgical patient
surgical risk
very elderly

Addition of Suvorexant to Ramelteon Therapy for Improved Sleep Quality with Reduced Delirium Risk in Acute Stroke Patients. Kawada, K. Ohta, T. Tanaka, K. Miyamura, M. Tanaka, S. Journal of Stroke and Cerebrovascular Diseases 2019

phosphorus 33
ramelteon
suvorexant
zolpidem
aged
article
body mass
brain infarction
cerebrovascular accident
cohort analysis
combination drug therapy
controlled study
daytime somnolence
delirium
disease association
female
hospitalization
human
logistic regression analysis
major clinical study
male
priority journal
retrospective study
risk factor
single blind procedure
sleep disorder
sleep quality

Age-dependent morbidity and mortality outcomes after surgical aortic valve replacement. Hussain, A. I. Auensen, A. Brunborg, C. Beitnes, J. O. Gullestad, L. Pettersen, K. I. Interactive cardiovascular and thoracic surgery 2018

NCT01794832
pacemaker
age
aged
aortic stenosis
aortic valve replacement
article
cause of death
cerebrovascular accident
clinical trial
cognition
cohort analysis
delirium
disease severity
female
hazard ratio
heart failure
heart infarction
hospital readmission
human
infection
length of stay
major clinical study
male
morbidity
mortality rate
mortality risk
New York Heart Association class
postoperative complication
priority journal
prospective study
quality of life
survival
transient ischemic attack
very elderly

Interventions for preventing intensive care unit delirium in adults. Herling, S. F. Greve, I. E. Vasilevskis, E. E. Egerod, I. Bekker Mortensen, C. Møller, A. M. Svenningsen, H. Thomsen, T. Cochrane Database of Systematic Reviews 2018

ISRCTN83567338
NCT00095251
NCT00466492
NCT00675363
NCT00824239
NCT01270269
NCT01274819
NCT01739933
NCT01785290
NCT01791296
NCT0196768
NCT01983800
NCT02245256
NCT02548923
NCT02612948
NCT02615340
NCT02932358
NCT03002701
NCT03095443
NCT03125252
NCT03172897
NCT03215745
dexmedetomidine
haloperidol
lorazepam
placebo
adult
APACHE
artificial ventilation
bradycardia
cognitive defect
cognitive therapy
coma
critically ill patient
delirium
environmental intervention
health care cost
hospital mortality
human
intensive care unit
intention to treat analysis
intervention study
length of stay
nursing intervention
outcome assessment
physiotherapy
priority journal
randomized controlled trial (topic)
review
sedation
seizure
sensitivity analysis
treatment duration
ventilator weaning

Mortality in people with dementia, delirium, and unspecified cognitive impairment in the general hospital: Prospective cohort study of 6,724 patients with 2 years follow-up. Hapca, S. Guthrie, B. Cvoro, V. Bu, F. Rutherford, A. C. Reynish, E. Donnan, P. T. Clinical Epidemiology 2018

aged
cognition assessment
cognitive defect
cohort analysis
comorbidity
controlled study
delirium
dementia
disease association
disease classification
female
follow up
functional status
general hospital
high risk patient
hospital admission
human
major clinical study
male
mortality
physical disease
prospective study
review
risk factor
very elderly

Neurofilament Light in the Serum and Cerebrospinal Fluid of Hip Fracture Patients with Delirium. Halaas, N. B. Blennow, K. Idland, A. V. Wyller, T. B. Ræder, J. Frihagen, F. Staff, A. C. Zetterberg, H. Watne, L. O. Dementia and Geriatric Cognitive Disorders 2018

aged
article
cerebrospinal fluid
controlled study
delirium
dementia
diagnosis
elective surgery
female
hip fracture
human
human tissue
major clinical study
male
neurofilament
preoperative evaluation
surgery
biological marker
endogenous compound

Investigating speech and language impairments in delirium: A preliminary case-control study. Green, S. Reivonen, S. Rutter, L. M. Nouzova, E. Duncan, N. Clarke, C. MacLullich, A. M. J. Tieges, Z. PLoS One 2018

aged
arousal
article
attention test
case control study
clinical article
cognitive defect
comprehension
controlled study
conversation
delirium
dementia
DSM-5
female
grammar
hospital patient
human
language ability
language disability
male
memory test
Richmond Agitation Sedation Scale
semantics
speech and language rehabilitation
speech disorder
task performance
written language

Elevated serum S-100β in patients with septic shock is associated with delirium. Erikson, K. Ala-Kokko, T. I. Koskenkari, J. Liisanantti, J. H. Kamakura, R. Herzig, K. H. Syrjälä, H. Acta Anaesthesiol Scand 2019

interleukin 6
neuron specific enolase
protein S100B
substance P
adult
aged
article
blood sampling
clinical article
controlled study
delirium
female
human
intensive care unit
male
multiple organ failure
observational study
priority journal
prospective study
protein blood level
septic shock
Sequential Organ Failure Assessment Score

A prospective, observational study of cerebrovascular autoregulation and its association with delirium following cardiac surgery. Chan, B. Aneman, A. Anaesthesia 2019

FORESIGHT Elite
IntelliVue MP70 Patient Monitor
patient monitor
analgesic agent
fentanyl
hypertensive factor
inotropic agent
nitroprusside sodium
propofol
adult
aphasia
article
autoregulation
cerebrovascular disease
cognitive defect
cohort analysis
controlled clinical trial
controlled study
delirium
female
heart surgery
human
impaired cerebrovascular autoregulation
intensive care unit
major clinical study
male
mean arterial pressure
near infrared spectroscopy
observational study
oximetry
postoperative complication
prospective study
surgical patient
tissue oxygenation

Dynamic cerebral autoregulation: A marker of post-operative delirium? Caldas, J. R. Panerai, R. B. Bor-Seng-Shu, E. Ferreira, G. S. R. Camara, L. Passos, R. H. de-Lima-Oliveira, M. Galas, F. R. B. G. Almeida, J. P. Nogueira, R. C. Mian, N. Gaiotto, F. A. Robinson, T. G. Hajjar, L. A. Clinical Neurophysiology 2018

NCT02143544
adult
article
autoregulation
blood flow velocity
blood pressure measurement
brain blood flow
cardiopulmonary bypass
coronary artery bypass graft
disease association
disease marker
female
heart surgery
human
major clinical study
male
observational study
postoperative delirium
preoperative period
priority journal
prospective study
surgical risk

The Golden Angels: Effects of trained volunteers on specialling and readmission rates for people with dementia and delirium in rural hospitals. Blair, A. Anderson, K. Bateman, C. International Psychogeriatrics 2018

hearing aid
visual aid
aged
article
clinical effectiveness
controlled clinical trial
controlled study
decubitus
delirium
dementia
drug use
falling
female
health program
hospital admission
hospital readmission
hospital volunteer
human
length of stay
major clinical study
male
medical education
mortality
nutrition
orientation
outcome assessment
patient care
patient safety
physical activity
prospective study
reproducibility
residential care
risk assessment
rural area

The effectiveness of non-pharmacological interventions in reducing the incidence and duration of delirium in critically ill patients: a systematic review and meta-analysis. Bannon, L. McGaughey, J. Verghis, R. Clarke, M. McAuley, D. F. Blackwood, B. Intensive Care Medicine 2018

adult
article
controlled study
critically ill patient
delirium
female
human
incidence
intensive care
male
meta analysis
outcome assessment
phototherapy
physiotherapy
randomized controlled trial (topic)
systematic review
voice

Blood Thiamine Level and Cognitive Function in Older Hospitalized Patients. Pourhassan, M. Angersbach, B. Lueg, G. Klimek, C. N. Wirth, R. J Geriatr Psychiatry Neurol 2018

delirium
dementia
depression
functional status
recovery
thiamine

Low doses of ketamine reduce delirium but not opiate consumption in mechanically ventilated and sedated ICU patients: A randomised double-blind control trial. Perbet, S. Verdonk, F. Godet, T. Jabaudon, M. Chartier, C. Cayot, S. Guerin, R. Morand, D. Bazin, J. E. Futier, E. Pereira, B. Constantin, J. M. Anaesth Crit Care Pain Med 2018

Consumption of opiates
Delirium
Intensive care unit
Ketamine infusion
Mechanical ventilation

CSF sodium at toxic levels precedes delirium in hip fracture patients. Hassel, B. Mariussen, E. Idland, A. V. Dahl, G. T. Raeder, J. Frihagen, F. Berg, J. P. Chaudhry, F. A. Wyller, T. B. Watne, L. O. Neurotoxicology 2018

Cerebrospinal fluid
Choroid plexus
Delirium
Potassium
Serum
Sodium

Relationship between the administration of nicardipine hydrochloride and the development of delirium in patients on mechanical ventilation. Zamami, Y. Kouno, Y. Niimura, T. Chuma, M. Imai, T. Mitsui, M. Koyama, T. Kayano, M. Okada, N. Hamano, H. Goda, M. Imanishi, M. Takechi, K. Horinouchi, Y. Kondo, Y. Yanagawa, H. Kitamura, Y. Sendo, T. Ujike, Y. Ishizawa, K. Pharmazie 2018
Prevalence and risk factors of delirium and subsyndromal delirium in Chinese older adults. Yam, K. K. Shea, Y. F. Chan, T. C. Chiu, K. C. Luk, J. K. Chu, L. W. Chan, F. H. Geriatrics & Gerontology International 2018

Chinese
delirium
prevalence
risk factors
subsyndromal delirium

Home-based Cognitive Prehabilitation in Older Surgical Patients: A Feasibility Study. Vlisides, P. E. Das, A. R. Thompson, A. M. Kunkler, B. Zierau, M. Cantley, M. J. McKinney, A. M. Giordani, B. J Neurosurg Anesthesiol 2018
Meta-analysis of Prevalence and Risk Factors for Delirium After Transcatheter Aortic Valve Implantation. Tilley, E. Psaltis, P. J. Loetscher, T. Davis, D. H. Harrison, S. L. Kim, S. Keage, H. A. D. Am J Cardiol 2018
Development and feasibility of a smartphone-based test for the objective detection and monitoring of attention impairments in delirium in the ICU. Tang, E. Laverty, M. Weir, A. Wilson, E. S. Walsh, T. S. Allerhand, M. Parks, S. MacLullich, A. M. J. Tieges, Z. J Crit Care 2018

Arousal
Attention Impairments
Case-Control Study
Cognitive Assessment
Delirium
Smartphone

Retrospective Analysis of Perioperative Variables Associated With Postoperative Delirium and Other Adverse Outcomes in Older Patients After Spine Surgery. Susano, M. J. Scheetz, S. D. Grasfield, R. H. Cheung, D. Xu, X. Kang, J. D. Smith, T. R. Lu, Y. Groff, M. W. Chi, J. H. Crosby, G. Culley, D. J. J Neurosurg Anesthesiol 2018
Delirium detection by a novel bispectral electroencephalography device in general hospital. Shinozaki, G. Chan, A. C. Sparr, N. A. Zarei, K. Gaul, L. N. Heinzman, J. T. Robles, J. Yuki, K. Chronis, T. J. Ando, T. Wong, T. Sabbagh, S. Weckmann, M. T. Lee, S. Yamada, T. Karam, M. D. Noiseux, N. O. Shinozaki, E. Cromwell, J. W. Psychiatry Clin Neurosci 2018

Aged
Aged, 80 and over
Brain/*physiopathology
Delirium/*diagnosis/physiopathology
Electroencephalography/*methods
Female
Humans
Male
Mass Screening
Middle Aged
Pilot Projects
*Point-of-Care Systems
delirium
electroencephalogram
point of care
power spectral analysis

Incremental cost and length of stay associated with postprocedure delirium in transcatheter and surgical aortic valve replacement patients in the United States. Potter, B. J. Thompson, C. Green, P. Clancy, S. Catheterization and Cardiovascular Interventions 2018

aortic
aortic valve disease
economics/cost-effectiveness
elderly patients
surgery
transcatheter valve implantation

Effect of regional versus general anaesthesia on postoperative delirium in elderly patients undergoing surgery for hip fracture: a systematic review. Patel, V. Champaneria, R. Dretzke, J. Yeung, J. BMJ Open 2018

general anaesthesia
hip fracture
regional anaesthesia
systematic review

The Role of Perioperative Statin Use in the Prevention of Delirium After Total Knee Replacement Under Spinal Anesthesia. Oh, T. K. Park, H. Y. Shin, H. J. Jeon, Y. T. Do, S. H. Hwang, J. W. J Arthroplasty 2018

analgesics
anesthesia
arthroplasty
delirium
hydroxymethylglutaryl coenzyme A reductase inhibitors

Observational Study Examining the Association of Baseline Frailty and Postcardiac Surgery Delirium and Cognitive Change. Nomura, Y. Nakano, M. Bush, B. Tian, J. Yamaguchi, A. Walston, J. Hasan, R. Zehr, K. Mandal, K. LaFlam, A. Neufeld, K. J. Kamath, V. Hogue, C. W. Brown, C. H. th Anesth Analg 2018
CAM-ICU may not be the optimal screening tool for early delirium screening in older emergency department patients: a prospective cohort study. Lucke, J. A. De Gelder, J. Blomaard, L. C. Fogteloo, A. J. Alsma, J. Schuit, S. C. E. Brink, A. De Groot, B. Blauw, G. J. Mooijaart, S. P. Eur J Emerg Med 2018
Relation of postoperative serum S100A12 levels to delirium and cognitive dysfunction occurring after hip fracture surgery in elderly patients. Li, Q. H. Yu, L. Yu, Z. W. Fan, X. L. Yao, W. X. Ji, C. Deng, F. Luo, X. Z. Sun, J. L. Brain Behav 2018

S100a12
cognitive dysfunction
delirium
elderly
hip fracture
postoperative

A scoping review to map empirical evidence regarding key domains and questions in the clinical pathway of delirium in palliative care. Lawlor, P. G. Rutkowski, N. A. MacDonald, A. R. Ansari, M. T. Sikora, L. Momoli, F. Kanji, S. Wright, D. K. Rosenberg, E. Hosie, A. Pereira, J. L. Meagher, D. Rice, J. Scott, J. Bush, S. H. J Pain Symptom Manage 2018

analytic framework
assessment
delirium
management
palliative care
prognosis

Arousal changes and delirium in acute medically-ill male older patients with and without dementia: a prospective study during hospitalization. Lagarto, L. Albuquerque, E. Loureiro, D. Vieira, F. Esteves, P. Neves, S. Teixeira-Verissimo, M. Cerejeira, J. Aging Ment Health 2018

Arousal
delirium
dementia

Incidence and Prevalence of Delirium Subtypes in an Adult ICU: A Systematic Review and Meta-Analysis. Krewulak, K. D. Stelfox, H. T. Leigh, J. P. Ely, E. W. Fiest, K. M. Crit Care Med 2018
Association between death and loss of stage N2 sleep features among critically Ill patients with delirium. Knauert, M. P. Gilmore, E. J. Murphy, T. E. Yaggi, H. K. Van Ness, P. H. Han, L. Hirsch, L. J. Pisani, M. A. J Crit Care 2018

Critical illness
Delirium
Electroencephalography
Encephalopathy
Polysomnography
Sleep

Preventing Postoperative Delirium After Major Noncardiac Thoracic Surgery-A Randomized Clinical Trial. Khan, B. A. Perkins, A. J. Campbell, N. L. Gao, S. Khan, S. H. Wang, S. Fuchita, M. Weber, D. J. Zarzaur, B. L. Boustani, M. A. Kesler, K. J Am Geriatr Soc 2018

Icu
cognition
delirium
esophagectomy
haloperidol

Effect of nonpharmacological interventions for the prevention of delirium in the intensive care unit: A systematic review and meta-analysis. Kang, J. Lee, M. Ko, H. Kim, S. Yun, S. Jeong, Y. Cho, Y. J Crit Care 2018

Delirium
Intensive care unit
Meta-analysis
Nonpharmacological
Prevention