What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Preoperative Cognitive Abnormality, Intraoperative Electroencephalogram Suppression, and Postoperative Delirium: A Mediation Analysis
- Authors
- Fritz, B. A. King, C. R. Ben Abdallah, A. Lin, N. Mickle, A. M. Budelier, T. P. Oberhaus, J. Park, D. Maybrier, H. R. Wildes, T. S. Avidan, M. S. Apakama, G. Aranake-Chrisinger, A. Bolzenius, J. Burton, J. Cui, V. Emmert, D. A. Goswami, S. Graetz, T. J. G
- Year
- 2020
- Journal
- Anesthesiology
- Abstract
WHAT WE ALREADY KNOW ABOUT THIS TOPIC: Postoperative delirium is common in older surgical patientsIntraoperative electroencephalogram suppression has been associated with postoperative deliriumPatients with preoperative cognitive impairment have an increased risk of developing postoperative delirium WHAT THIS ARTICLE TELLS US THAT IS NEW: The indirect effect of intraoperative electroencephalogram suppression on the development of postoperative delirium among patients with preexisting cognitive impairment is probably small but nonzeroApproximately 28 cognitively impaired patients would need to be kept out of electroencephalogram suppression to avoid 1 case of postoperative delirium BACKGROUND:: Postoperative delirium is a common complication that hinders recovery after surgery. Intraoperative electroencephalogram suppression has been linked to postoperative delirium, but it is unknown if this relationship is causal or if electroencephalogram suppression is merely a marker of underlying cognitive abnormalities. The hypothesis of this study was that intraoperative electroencephalogram suppression mediates a nonzero portion of the effect between preoperative abnormal cognition and postoperative delirium. METHODS: This is a prespecified secondary analysis of the Electroencephalography Guidance of Anesthesia to Alleviate Geriatric Syndromes (ENGAGES) randomized trial, which enrolled patients age 60 yr or older undergoing surgery with general anesthesia at a single academic medical center between January 2015 and May 2018. Patients were randomized to electroencephalogram-guided anesthesia or usual care. Preoperative abnormal cognition was defined as a composite of previous delirium, Short Blessed Test cognitive score greater than 4 points, or Eight Item Interview to Differentiate Aging and Dementia score greater than 1 point. Duration of intraoperative electroencephalogram suppression was defined as number of minutes with suppression ratio greater than 1%. Postoperative delirium was detected via Confusion Assessment Method or chart review on postoperative days 1 to 5. RESULTS: Among 1,113 patients, 430 patients showed evidence of preoperative abnormal cognition. These patients had an increased incidence of postoperative delirium (151 of 430 [35%] vs.123 of 683 [18%], P < 0.001). Of this 17.2% total effect size (99.5% CI, 9.3 to 25.1%), an absolute 2.4% (99.5% CI, 0.6 to 4.8%) was an indirect effect mediated by electroencephalogram suppression, while an absolute 14.8% (99.5% CI, 7.2 to 22.5%) was a direct effect of preoperative abnormal cognition. Randomization to electroencephalogram-guided anesthesia did not change the mediated effect size (P = 0.078 for moderation). CONCLUSIONS: A small portion of the total effect of preoperative abnormal cognition on postoperative delirium was mediated by electroencephalogram suppression. Study precision was too low to determine if the intervention changed the mediated effect.
- PMID
- Keywords
adult
aging
article
complication
convalescence
effect size
electroencephalogram
electroencephalography
female
general anesthesia
human
incidence
interview
major clinical study
male
medical record review
mentally disabled person
postoperative delirium
preoperative evaluation
randomization
randomized controlled trial
secondary analysis
surgery
university hospital
- Page(s)
- Volume
- Issue
Title | Authors | Journal | Year | Keywords |
---|---|---|---|---|
Risk Factors of Postoperative Delirium in the Intensive Care Unit After Liver Transplantation. | Lee, H. Oh, S. Y. Yu, J. H. Kim, J. Yoon, S. Ryu, H. G. | World J Surg | 2018 | |
Risk Factors for Postoperative Delirium After Deep Brain Stimulation Surgery for Parkinson's Disease. | Tanaka, M. Tani, N. Maruo, T. Oshino, S. Hosomi, K. Saitoh, Y. Kishima, H. | World Neurosurg | 2018 |
Deep Brain Stimulation |
The relationship of delirium and risk factors in cardiology intensive care unit patients with the nursing workload. | Ozturk Birge, A. Beduk, T. | J Clin Nurs | 2018 |
Critical Care |
Protocol for a single-centre prospective observational study of postoperative delirium following total joint arthroplasties among South East Asians. | Abdullah, H. R. Tan, S. R. Lee, S. J. Bin Abd Razak, H. R. Seet, R. H. Ying, H. Sethi, E. Sim, E. Y. | BMJ Open | 2018 |
*delirium |
Preoperative statins are associated with a reduced risk of postoperative delirium following vascular surgery. | Lee, D. S. Lee, M. Y. Park, C. M. Kim, D. I. Kim, Y. W. Park, Y. J. | PLoS One | 2018 | |
Predisposing and precipitating factors for delirium in community-dwelling older adults admitted to hospital with this condition: A prospective case series. | Magny, E. Le Petitcorps, H. Pociumban, M. Bouksani-Kacher, Z. Pautas, É Belmin, J. Bastuji-Garin, S. Lafuente-Lafuente, C. | PLoS One | 2018 |
aged |
Predicting excess cost for older inpatients with clinical complexity: A retrospective cohort study examining cognition, comorbidities and complications | Bail, K. Draper, B. Berry, H. Karmel, R. Goss, J. | PLoS One | 2018 |
adult |
Pilot Study of a Two-Step Delirium Detection Protocol Administered By Certified Nursing Assistants, Physicians, and Registered Nurses. | Fick, D. M. Inouye, S. K. McDermott, C. Zhou, W. Ngo, L. Gallagher, J. McDowell, J. Penrod, J. Siuta, J. Covaleski, T. Marcantonio, E. R. | J Gerontol Nurs | 2018 | |
Perioperative hyperglycaemia and neurocognitive outcome after surgery: a systematic review. | Hermanides, J. Qeva, E. Preckel, B. Bilotta, F. | Minerva Anestesiol | 2018 | |
Low-dose Nocturnal Dexmedetomidine Prevents ICU Delirium: A Randomized, Placebo-controlled Trial. | Skrobik, Y. Duprey, M. S. Hill, N. S. Devlin, J. W. | Am J Respir Crit Care Med | 2018 |
delirium, sleep, intensive care, dexmedetomidine, randomized controlled trial |
Low peripheral levels of insulin growth factor-1 are associated with high incidence of delirium among elderly patients: A systematic review and meta-analysis. | Li, D. J. Tseng, P. T. Stubbs, B. Chen, T. Y. Lin, P. Y. Chen, S. L. Thompson, T. Adamis, D. Chu, C. S. | Arch Gerontol Geriatr | 2018 |
Biomarker |
Is anemia associated with cognitive impairment and delirium among older acute surgical patients? | Myint, P. K. Owen, S. McCarthy, K. Pearce, L. Moug, S. J. Stechman, M. J. Hewitt, J. Carter, B. | Geriatrics & Gerontology International | 2018 |
anemia |
Intraoperative Sedation With Dexmedetomidine is Superior to Propofol for Elderly Patients Undergoing Hip Arthroplasty: A Prospective Randomized Controlled Study. | Mei, B. Meng, G. Xu, G. Cheng, X. Chen, S. Zhang, Y. Zhang, M. Liu, X. Gu, E. | Clin J Pain | 2018 | |
Infrared pupillometry helps to detect and predict delirium in the post-anesthesia care unit. | Yang E, Kreuzer M, Hesse S, Davari P, Lee SC, García PS | Journal of clinical monitoring and computing | 2017 |
PLR-200 |
Influence of Physical Restraint on Delirium of Adult Patients in ICU: A Nested Case-Control Study. | Pan, Y. Jiang, Z. Changrong, Y. Wang, L. Zhang, J. Zhou, J. Tao, M. Quan, M. Wu, Q. | J Clin Nurs | 2018 |
Delirium |
Incidence of delirium in the Canadian emergency department and its consequences on hospital length of stay: A prospective observational multicentre cohort study. | Émond, M. Boucher, V. Carmichael, P. H. Voyer, P. Pelletier, M. Gouin, É Daoust, R. Berthelot, S. Lamontagne, M. E. Morin, M. Lemire, S. Minh Vu, T. T. Nadeau, A. Rheault, M. Juneau, L. Le Sage, N. Lee, J. | BMJ Open | 2018 |
aged |
Impact of timing and duration of postoperative delirium: a retrospective observational study | Lee, H. Ju, J. W. Oh, S. Y. Kim, J. Jung, C. W. Ryu, H. G. | Surgery | 2018 | |
Frequency and risk factors for subsyndromal delirium in an intensive care unit. | Yamada, C. Iwawaki, Y. Harada, K. Fukui, M. Morimoto, M. Yamanaka, R. | Intensive Crit Care Nurs | 2018 |
Delirium |
Focusing on Inattention: The Diagnostic Accuracy of Brief Measures of Inattention for Detecting Delirium. | Marra, A. Jackson, J. C. Ely, E. W. Graves, A. J. Schnelle, J. F. Dittus, R. S. Wilson, A. Han, J. H. | J Hosp Med | 2018 | |
Feasibility of Cognitive Training in Critically Ill Patients: A Pilot Study. | Wassenaar, A. Rood, P. Boelen, D. Schoonhoven, L. Pickkers, P. van den Boogaard, M. | Am J Crit Care | 2018 | |
Evaluation of a sound environment intervention in an ICU: A feasibility study. | Johansson, L. Lindahl, B. Knutsson, S. Ogren, M. Persson Waye, K. Ringdal, M. | Aust Crit Care | 2018 |
Complex intervention |
Effects of Haloperidol on Delirium in Adult Patients: A Systematic Review and Meta-analysis. | Shen, Y. Z. Peng, K. Zhang, J. Meng, X. W. Ji, F. | Med Princ Pract | 2018 | |
The effect of the timing and dose of dexmedetomidine on postoperative delirium in elderly patients after laparoscopic major non-cardiac surgery: A double blind randomized controlled study. | Lee, C. Lee, C. H. Lee, G. Lee, J. Hwang, J. | J Clin Anesth | 2018 |
Cytokine |
Effect of organisational factors on the variation in incidence of delirium in intensive care unit patients: A systematic review and meta-regression analysis. | Rood, P. Huisman-de Waal, G. Vermeulen, H. Schoonhoven, L. Pickkers, P. van den Boogaard, M. | Aust Crit Care | 2018 |
Critical care |
Effect of Administration of Ramelteon, a Melatonin Receptor Agonist, on the Duration of Stay in the ICU: A Single-Center Randomized Placebo-Controlled Trial. | Nishikimi, M. Numaguchi, A. Takahashi, K. Miyagawa, Y. Matsui, K. Higashi, M. Makishi, G. Matsui, S. Matsuda, N. | Crit Care Med | 2018 | |
Diagnostic accuracy of delirium assessment methods in critical care patients | Barman, A. Pradhan, D. Bhattacharyya, P. Dey, S. Bhattacharjee, A. Tesia, S. S. Mitra, J. K. | Journal of Critical Care | 2018 |
Acute Physiology and Chronic Health Evaluation II |
Delirium in ICU Patients Following Cardiac Surgery: An Observational Study. | Simeone, S. Pucciarelli, G. Perrone, M. Rea, T. Gargiulo, G. Guillari, A. Castellano, G. Di Tommaso, L. Niola, M. Iannelli, G. | J Clin Nurs | 2018 |
Icu |
Clinical phenotypes of delirium during critical illness and severity of subsequent long-term cognitive impairment: a prospective cohort study. | Girard, T. D. Thompson, J. L. Pandharipande, P. P. Brummel, N. E. Jackson, J. C. Patel, M. B. Hughes, C. G. Chandrasekhar, R. Pun, B. T. Boehm, L. M. Elstad, M. R. Goodman, R. B. Bernard, G. R. Dittus, R. S. Ely, E. W. | Lancet Respir Med | 2018 | |
Postoperative Complications Associated With Spine Surgery in Patients Older Than 90 Years: A Multicenter Retrospective Study. | Kobayashi, K. Imagama, S. Sato, K. Kato, F. Kanemura, T. Yoshihara, H. Sakai, Y. Shinjo, R. Hachiya, Y. Osawa, Y. Matsubara, Y. Ando, K. Nishida, Y. Ishiguro, N. | Global Spine J | 2018 |
complications |
Do the Phenotypes of Symptom Fluctuation Differ Among Motor Subtypes in Patients With Delirium?. | Kim, S. Y. Kim, J. M. Kim, S. W. Kim, E. S. Kang, H. J. Lee, J. Y. Bae, K. Y. Shin, I. S. Yoon, J. S. | J Pain Symptom Manage | 2018 |
Delirium |
Delirium and its consequences in the specialized palliative care unit: Validation of the Korean version of Memorial Delirium Assessment Scale. | Kang, B. Kim, Y. J. Suh, S. W. Son, K. L. Ahn, G. S. Park, H. Y. | Psycho-Oncology | 2018 |
adult |
The Motoric Types of Delirium and Estimated Blood Loss during Perioperative Period in Orthopedic Elderly Patients. | Hong, N. Park, J. Y. | Biomed Res Int | 2018 | |
CSF sTREM2 in delirium-relation to Alzheimer's disease CSF biomarkers Abeta42, t-tau and p-tau. | Henjum, K. Quist-Paulsen, E. Zetterberg, H. Blennow, K. Nilsson, L. N. G. Watne, L. O. | J Neuroinflammation | 2018 |
Alzheimer’s disease |
CSF biomarkers in delirium: a systematic review. | Hall RJ, Watne LO, Cunningham E, Zetterberg H, Shenkin SD, Wyller TB, MacLullich AMJ | International journal of geriatric psychiatry | 2017 |
CSF biomarkers |
Prediction of ICU Delirium: Validation of Current Delirium Predictive Models in Routine Clinical Practice. | Green, C. Bonavia, W. Toh, C. Tiruvoipati, R. | Crit Care Med | 2018 | |
The Incidence of Recorded Delirium Episodes Before and After Dementia Diagnosis: Differences Between Dementia With Lewy Bodies and Alzheimer's Disease. | FitzGerald, J. M. Perera, G. Chang-Tave, A. Price, A. Rajkumar, A. P. Bhattarai, M. O'Brien, J. T. Ballard, C. Aarsland, D. Stewart, R. Mueller, C. | J Am Med Dir Assoc | 2018 |
Alzheimer’s disease |
Pain and delirium in people with dementia in the acute general hospital setting. | Feast, A. R. White, N. Lord, K. Kupeli, N. Vickerstaff, V. Sampson, E. L. | Age Ageing | 2018 | |
Environmental factors and risk of delirium in geriatric patients: an observational study. | Evensen, S. Saltvedt, I. Lydersen, S. Wyller, T. B. Taraldsen, K. Sletvold, O. | BMC Geriatr | 2018 |
Delirium |
Validity of a screening method for delirium risk in older patients admitted to a general hospital in the Netherlands. | Ettema, R. Heim, N. Hamaker, M. Emmelot-Vonk, M. van der Mast, R. Schuurmans, M. | General Hospital Psychiatry | 2018 |
aged |
Indwelling urinary catheters, aortic valve treatment and delirium: a prospective cohort study. | Eide, L. S. Ranhoff, A. H. Lauck, S. Fridlund, B. Haaverstad, R. Hufthammer, K. O. Kuiper, K. K. J. Nordrehaug, J. E. Norekval, T. M. | BMJ Open | 2018 |
Savr |
Diagnostic value of NT-proCNP compared to NSE and S100B in cerebrospinal fluid and plasma of patients with sepsis-associated encephalopathy. | Ehler, J. Saller, T. Wittstock, M. Rommer, P. S. Chappell, D. Zwissler, B. Grossmann, A. Richter, G. Reuter, D. A. Noldge-Schomburg, G. Sauer, M. | Neurosci Lett | 2018 |
Biomarker |
Exploration of Relationships Between Postoperative Pain and Subsyndromal Delirium in Older Adults. | Denny, D. L. Such, T. L. | Nurs Res | 2018 | |
Prediction of Incident Delirium Using a Random Forest classifier. | Corradi, J. P. Thompson, S. Mather, J. F. Waszynski, C. M. Dicks, R. S. | J Med Syst | 2018 |
Decision support |
The hip fracture surgery in elderly patients (HIPELD) study to evaluate xenon anaesthesia for the prevention of postoperative delirium: a multicentre, randomized clinical trial. | Coburn, M. Sanders, R. D. Maze, M. Nguyên-Pascal, M. L. Rex, S. Garrigues, B. Carbonell, J. A. Garcia-Perez, M. L. Stevanovic, A. Kienbaum, P. Neukirchen, M. Schaefer, M. S. Borghi, B. van Oven, H. Tognù, A. Al Tmimi, L. Eyrolle, L. Langeron, O. Capdevi | British Journal of Anaesthesia | 2018 |
C reactive protein |
Effect of a single pre-operative 125 mg dose of methylprednisolone on postoperative delirium in hip fracture patients; a randomised, double-blind, placebo-controlled trial. | Clemmesen, C. G. Lunn, T. H. Kristensen, M. T. Palm, H. Foss, N. B. | Anaesthesia | 2018 |
delirium |
Identifying Patterns of Delirium in Hospitalized Patients on Dexamethasone Using a Chart Abstraction Tool. | Chang, J. T. Atayee, R. S. Edmonds, K. P. | Journal of Pain and Palliative Care Pharmacotherapy | 2018 |
dexamethasone |
Detecting delirium in elderly medical emergency patients: validation and subsequent modification of the German Nursing Delirium Screening Scale. | Brich, J. Baten, V. Wussmann, J. Heupel-Reuter, M. Perlov, E. Kloppel, S. Busch, H. J. | Intern Emerg Med | 2018 |
Delirium |
Mobilizing older adults: A multi-site, exploratory and observational study on patients enrolled in the Hospital Elder Life Program (HELP). | Babine, R. L. Hyrkas, K. E. McKenzie, C. G. Wierman, H. R. | Geriatr Nurs | 2018 |
Older adults |
Validation of the Stanford Proxy Test for Delirium (S-PTD) among critical and noncritical patients. | Alosaimi, F. D. Alghamdi, A. Alsuhaibani, R. Alhammad, G. Albatili, A. Albatly, L. Althomali, B. Aljamaan, F. Maldonado, J. R. | J Psychosom Res | 2018 |
Delirium |
Impact of an Antipsychotic Discontinuation Bundle During Transitions of Care in Critically Ill Patients. | D’Angelo, R. G. Rincavage, M. Tata, A. L. Millstein, L. S. Gulati, M. S. Flurie, R. W. Gonzales, J. P. | J Intensive Care Med | 2019 |
urinary catheter |
Living at home after emergency hospital admission: Prospective cohort study in older adults with and without cognitive spectrum disorder. | Burton, J. K. Guthrie, B. Hapca, S. M. Cvoro, V. Donnan, P. T. Reynish, E. L. | BMC Medicine | 2018 |
aged |
The Association Between C-Reactive Protein and Postoperative Delirium Differs by Catechol-O-Methyltransferase Genotype. | Vasunilashorn, S. M. Ngo, L. H. Jones, R. N. Inouye, S. K. Hall, K. T. Gallagher, J. Dillon, S. T. Xie, Z. Libermann, T. A. Marcantonio, E. R. | American Journal of Geriatric Psychiatry | 2019 |
acute phase protein |
Risk factors associated with acute in-hospital delirium for patients diagnosed with a hip fracture in the emergency department. | Thompson, C. Brienza, V. J. M. Sandre, A. Caine, S. Borgundvaag, B. McLeod, S. | Canadian Journal of Emergency Medicine | 2018 |
codeine |
A Comparison of Early, Late, and No Treatment of Intensive Care Unit Delirium With Antipsychotics: A Retrospective Cohort Study. | Thom, R. P. Bui, M. P. Rosner, B. Teslyar, P. Levy-Carrick, N. C. Klompas, M. | The Primary Care Companion for CNS Disorders | 2018 |
neuroleptic agent |
Postoperative Pain Management Strategies and Delirium After Transapical Aortic Valve Replacement: A Randomized Controlled Trial. | Strike, E. Arklina, B. Stradins, P. Cusimano, R. J. Osten, M. Horlick, E. Styra, R. Poonawala, H. Carroll, J. Djaiani, G. | Journal of Cardiothoracic and Vascular Anesthesia | 2018 |
adult |
Effect of Depth of Sedation in Older Patients Undergoing Hip Fracture Repair on Postoperative Delirium: The STRIDE Randomized Clinical Trial. | Sieber, F. E. Neufeld, K. J. Gottschalk, A. Bigelow, G. E. Oh, E. S. Rosenberg, P. B. Mears, S. C. Stewart, K. J. Ouanes, J. P. P. Jaberi, M. Hasenboehler, E. A. Li, T. Wang, N. Y. | JAMA Surg | 2018 |
local anesthetic agent |
Incidence of Delirium in Critically Ill Cancer Patients. | Sánchez-Hurtado, L. A. Hernández-Sánchez, N. Del Moral-Armengol, M. Guevara-García, H. García-Guillén, F. J. Herrera-Gómez, Á Ñamendys-Silva, S. A. | Pain Research & Management | 2018 |
adult |
Dispersion in Scores on the Richmond Agitation and Sedation Scale as a Measure of Delirium in Patients with Subdural Hematomas. | Robinson, D. Thompson, S. Bauerschmidt, A. Melmed, K. Couch, C. Park, S. Agarwal, S. Roh, D. Connolly, E. S. Claassen, J. | Neurocritical Care | 2018 |
adult |
Underdiagnosis of delirium in the elderly in acute care hospital settings: lessons not learned. | Ritter, S. R. F. Cardoso, A. F. Lins, M. M. P. Zoccoli, T. L. V. Freitas, M. P. D. Camargos, E. F. | Psychogeriatrics | 2018 |
aged |
Risk Factors and Hospital Mortality in Surgical and Non-surgical Patients with Delirium. | Restrepo, D. Duque, M. Montoya, L. Berrouet, M. C. Rojas, M. Lopera, G. Giraldo, K. | Revista Colombiana de Psiquiatria | 2018 |
cholinergic receptor blocking agent |
Caring for Critically Ill Patients with the ABCDEF Bundle: Results of the ICU Liberation Collaborative in Over 15,000 Adults. | Pun, B. T. Balas, M. C. Barnes-Daly, M. A. Thompson, J. L. Aldrich, J. M. Barr, J. Byrum, D. Carson, S. S. Devlin, J. W. Engel, H. J. Esbrook, C. L. Hargett, K. D. Harmon, L. Hielsberg, C. Jackson, J. C. Kelly, T. L. Kumar, V. Millner, L. Morse, A. Perme, | Crit Care Med | 2019 |
adult |
Effects of Perioperative Dexmedetomidine on Postoperative Mortality and Morbidity: A Systematic Review and Meta-analysis | Peng, K. Ji, F. H. Liu, H. Y. Zhang, J. Chen, Q. C. Jiang, Y. H. | Clinical Therapeutics | 2018 |
adult |
Relation Between Delirium and Anticholinergic Drug Burden in a Cohort of Hospitalized Older Patients: An Observational Study. | Pasina, L. Colzani, L. Cortesi, L. Tettamanti, M. Zambon, A. Nobili, A. Mazzone, A. Mazzola, P. Annoni, G. Bellelli, G. | Drugs Aging | 2018 |
adverse event |
Neopterin and mini-mental state examination scores, two independent risk factors for postoperative delirium in elderly patients with open abdominal surgery. | Miao, S. Shen, P. Zhang, Q. Wang, H. Shen, J. Wang, G. Lv, D. | Journal of Cancer Research and Therapeutics | 2018 |
C reactive protein |
Reliability and accuracy of delirium assessments among investigators at multiple international centres. | Maybrier, H. R. Mickle, A. M. Escallier, K. E. Lin, N. Schmitt, E. M. Upadhyayula, R. T. Wildes, T. S. Mashour, G. A. Palihnich, K. Inouye, S. K. Avidan, M. S. | BMJ Open | 2018 |
NCT01690988 |
Does the melatonin receptor 1B gene polymorphism have a role in postoperative delirium? | Mahanna-Gabrielli, E. Miano, T. A. Augoustides, J. G. Kim, C. Bavaria, J. E. Andrew Kofke, W. | PLoS ONE | 2018 |
adult |
Volatile anaesthetics and postoperative delirium in older surgical patients—A secondary analysis of prospective cohort studies | Kinjo, S. Lim, E. Magsaysay, M. V. Sands, L. P. Leung, J. M. | Acta Anaesthesiol Scand | 2019 |
desflurane |
Addition of Suvorexant to Ramelteon Therapy for Improved Sleep Quality with Reduced Delirium Risk in Acute Stroke Patients. | Kawada, K. Ohta, T. Tanaka, K. Miyamura, M. Tanaka, S. | Journal of Stroke and Cerebrovascular Diseases | 2019 |
phosphorus 33 |
Age-dependent morbidity and mortality outcomes after surgical aortic valve replacement. | Hussain, A. I. Auensen, A. Brunborg, C. Beitnes, J. O. Gullestad, L. Pettersen, K. I. | Interactive cardiovascular and thoracic surgery | 2018 |
NCT01794832 |
Interventions for preventing intensive care unit delirium in adults. | Herling, S. F. Greve, I. E. Vasilevskis, E. E. Egerod, I. Bekker Mortensen, C. Møller, A. M. Svenningsen, H. Thomsen, T. | Cochrane Database of Systematic Reviews | 2018 |
ISRCTN83567338 |
Mortality in people with dementia, delirium, and unspecified cognitive impairment in the general hospital: Prospective cohort study of 6,724 patients with 2 years follow-up. | Hapca, S. Guthrie, B. Cvoro, V. Bu, F. Rutherford, A. C. Reynish, E. Donnan, P. T. | Clinical Epidemiology | 2018 |
aged |
Neurofilament Light in the Serum and Cerebrospinal Fluid of Hip Fracture Patients with Delirium. | Halaas, N. B. Blennow, K. Idland, A. V. Wyller, T. B. Ræder, J. Frihagen, F. Staff, A. C. Zetterberg, H. Watne, L. O. | Dementia and Geriatric Cognitive Disorders | 2018 |
aged |
Investigating speech and language impairments in delirium: A preliminary case-control study. | Green, S. Reivonen, S. Rutter, L. M. Nouzova, E. Duncan, N. Clarke, C. MacLullich, A. M. J. Tieges, Z. | PLoS One | 2018 |
aged |
Elevated serum S-100β in patients with septic shock is associated with delirium. | Erikson, K. Ala-Kokko, T. I. Koskenkari, J. Liisanantti, J. H. Kamakura, R. Herzig, K. H. Syrjälä, H. | Acta Anaesthesiol Scand | 2019 |
interleukin 6 |
A prospective, observational study of cerebrovascular autoregulation and its association with delirium following cardiac surgery. | Chan, B. Aneman, A. | Anaesthesia | 2019 |
FORESIGHT Elite |
Dynamic cerebral autoregulation: A marker of post-operative delirium? | Caldas, J. R. Panerai, R. B. Bor-Seng-Shu, E. Ferreira, G. S. R. Camara, L. Passos, R. H. de-Lima-Oliveira, M. Galas, F. R. B. G. Almeida, J. P. Nogueira, R. C. Mian, N. Gaiotto, F. A. Robinson, T. G. Hajjar, L. A. | Clinical Neurophysiology | 2018 |
NCT02143544 |
The Golden Angels: Effects of trained volunteers on specialling and readmission rates for people with dementia and delirium in rural hospitals. | Blair, A. Anderson, K. Bateman, C. | International Psychogeriatrics | 2018 |
hearing aid |
The effectiveness of non-pharmacological interventions in reducing the incidence and duration of delirium in critically ill patients: a systematic review and meta-analysis. | Bannon, L. McGaughey, J. Verghis, R. Clarke, M. McAuley, D. F. Blackwood, B. | Intensive Care Medicine | 2018 |
adult |
Blood Thiamine Level and Cognitive Function in Older Hospitalized Patients. | Pourhassan, M. Angersbach, B. Lueg, G. Klimek, C. N. Wirth, R. | J Geriatr Psychiatry Neurol | 2018 |
delirium |
Low doses of ketamine reduce delirium but not opiate consumption in mechanically ventilated and sedated ICU patients: A randomised double-blind control trial. | Perbet, S. Verdonk, F. Godet, T. Jabaudon, M. Chartier, C. Cayot, S. Guerin, R. Morand, D. Bazin, J. E. Futier, E. Pereira, B. Constantin, J. M. | Anaesth Crit Care Pain Med | 2018 |
Consumption of opiates |
CSF sodium at toxic levels precedes delirium in hip fracture patients. | Hassel, B. Mariussen, E. Idland, A. V. Dahl, G. T. Raeder, J. Frihagen, F. Berg, J. P. Chaudhry, F. A. Wyller, T. B. Watne, L. O. | Neurotoxicology | 2018 |
Cerebrospinal fluid |
Relationship between the administration of nicardipine hydrochloride and the development of delirium in patients on mechanical ventilation. | Zamami, Y. Kouno, Y. Niimura, T. Chuma, M. Imai, T. Mitsui, M. Koyama, T. Kayano, M. Okada, N. Hamano, H. Goda, M. Imanishi, M. Takechi, K. Horinouchi, Y. Kondo, Y. Yanagawa, H. Kitamura, Y. Sendo, T. Ujike, Y. Ishizawa, K. | Pharmazie | 2018 | |
Prevalence and risk factors of delirium and subsyndromal delirium in Chinese older adults. | Yam, K. K. Shea, Y. F. Chan, T. C. Chiu, K. C. Luk, J. K. Chu, L. W. Chan, F. H. | Geriatrics & Gerontology International | 2018 |
Chinese |
Home-based Cognitive Prehabilitation in Older Surgical Patients: A Feasibility Study. | Vlisides, P. E. Das, A. R. Thompson, A. M. Kunkler, B. Zierau, M. Cantley, M. J. McKinney, A. M. Giordani, B. | J Neurosurg Anesthesiol | 2018 | |
Meta-analysis of Prevalence and Risk Factors for Delirium After Transcatheter Aortic Valve Implantation. | Tilley, E. Psaltis, P. J. Loetscher, T. Davis, D. H. Harrison, S. L. Kim, S. Keage, H. A. D. | Am J Cardiol | 2018 | |
Development and feasibility of a smartphone-based test for the objective detection and monitoring of attention impairments in delirium in the ICU. | Tang, E. Laverty, M. Weir, A. Wilson, E. S. Walsh, T. S. Allerhand, M. Parks, S. MacLullich, A. M. J. Tieges, Z. | J Crit Care | 2018 |
Arousal |
Retrospective Analysis of Perioperative Variables Associated With Postoperative Delirium and Other Adverse Outcomes in Older Patients After Spine Surgery. | Susano, M. J. Scheetz, S. D. Grasfield, R. H. Cheung, D. Xu, X. Kang, J. D. Smith, T. R. Lu, Y. Groff, M. W. Chi, J. H. Crosby, G. Culley, D. J. | J Neurosurg Anesthesiol | 2018 | |
Delirium detection by a novel bispectral electroencephalography device in general hospital. | Shinozaki, G. Chan, A. C. Sparr, N. A. Zarei, K. Gaul, L. N. Heinzman, J. T. Robles, J. Yuki, K. Chronis, T. J. Ando, T. Wong, T. Sabbagh, S. Weckmann, M. T. Lee, S. Yamada, T. Karam, M. D. Noiseux, N. O. Shinozaki, E. Cromwell, J. W. | Psychiatry Clin Neurosci | 2018 |
Aged |
Incremental cost and length of stay associated with postprocedure delirium in transcatheter and surgical aortic valve replacement patients in the United States. | Potter, B. J. Thompson, C. Green, P. Clancy, S. | Catheterization and Cardiovascular Interventions | 2018 |
aortic |
Effect of regional versus general anaesthesia on postoperative delirium in elderly patients undergoing surgery for hip fracture: a systematic review. | Patel, V. Champaneria, R. Dretzke, J. Yeung, J. | BMJ Open | 2018 |
general anaesthesia |
The Role of Perioperative Statin Use in the Prevention of Delirium After Total Knee Replacement Under Spinal Anesthesia. | Oh, T. K. Park, H. Y. Shin, H. J. Jeon, Y. T. Do, S. H. Hwang, J. W. | J Arthroplasty | 2018 |
analgesics |
Observational Study Examining the Association of Baseline Frailty and Postcardiac Surgery Delirium and Cognitive Change. | Nomura, Y. Nakano, M. Bush, B. Tian, J. Yamaguchi, A. Walston, J. Hasan, R. Zehr, K. Mandal, K. LaFlam, A. Neufeld, K. J. Kamath, V. Hogue, C. W. Brown, C. H. th | Anesth Analg | 2018 | |
CAM-ICU may not be the optimal screening tool for early delirium screening in older emergency department patients: a prospective cohort study. | Lucke, J. A. De Gelder, J. Blomaard, L. C. Fogteloo, A. J. Alsma, J. Schuit, S. C. E. Brink, A. De Groot, B. Blauw, G. J. Mooijaart, S. P. | Eur J Emerg Med | 2018 | |
Relation of postoperative serum S100A12 levels to delirium and cognitive dysfunction occurring after hip fracture surgery in elderly patients. | Li, Q. H. Yu, L. Yu, Z. W. Fan, X. L. Yao, W. X. Ji, C. Deng, F. Luo, X. Z. Sun, J. L. | Brain Behav | 2018 |
S100a12 |
A scoping review to map empirical evidence regarding key domains and questions in the clinical pathway of delirium in palliative care. | Lawlor, P. G. Rutkowski, N. A. MacDonald, A. R. Ansari, M. T. Sikora, L. Momoli, F. Kanji, S. Wright, D. K. Rosenberg, E. Hosie, A. Pereira, J. L. Meagher, D. Rice, J. Scott, J. Bush, S. H. | J Pain Symptom Manage | 2018 |
analytic framework |
Arousal changes and delirium in acute medically-ill male older patients with and without dementia: a prospective study during hospitalization. | Lagarto, L. Albuquerque, E. Loureiro, D. Vieira, F. Esteves, P. Neves, S. Teixeira-Verissimo, M. Cerejeira, J. | Aging Ment Health | 2018 |
Arousal |
Incidence and Prevalence of Delirium Subtypes in an Adult ICU: A Systematic Review and Meta-Analysis. | Krewulak, K. D. Stelfox, H. T. Leigh, J. P. Ely, E. W. Fiest, K. M. | Crit Care Med | 2018 | |
Association between death and loss of stage N2 sleep features among critically Ill patients with delirium. | Knauert, M. P. Gilmore, E. J. Murphy, T. E. Yaggi, H. K. Van Ness, P. H. Han, L. Hirsch, L. J. Pisani, M. A. | J Crit Care | 2018 |
Critical illness |
Preventing Postoperative Delirium After Major Noncardiac Thoracic Surgery-A Randomized Clinical Trial. | Khan, B. A. Perkins, A. J. Campbell, N. L. Gao, S. Khan, S. H. Wang, S. Fuchita, M. Weber, D. J. Zarzaur, B. L. Boustani, M. A. Kesler, K. | J Am Geriatr Soc | 2018 |
Icu |
Effect of nonpharmacological interventions for the prevention of delirium in the intensive care unit: A systematic review and meta-analysis. | Kang, J. Lee, M. Ko, H. Kim, S. Yun, S. Jeong, Y. Cho, Y. | J Crit Care | 2018 |
Delirium |