NIDUS Delirium Bibliography

Delirium Bibliography books graphic What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title: Relevance of Preoperative Cognitive Impairment for Predicting Postoperative Delirium in Surgical Medicine: A Prospective Cohort Study

Authors: Moellmann, H. L. Alhammadi, E. Olbrich, P. Frohnhofen, H.

Year: 2024

Journal: Geriatrics (Basel)

Abstract: BACKGROUND: Post-operative delirium is a dreaded complication after surgery in older patients. The identification of risk factors for delirium and comprehensive geriatric assessment is an extensive part of recent research. However, the preoperative assessment of risk factors, such as impaired cognition, is frequently not standardized. METHODS: A comprehensive preoperative assessment was performed in 421 surgical patients to investigate the impact of preoperative cognitive impairment (PCI) on the risk of delirium and to evaluate appropriate screening tools (Six-item screener (SIS) and clock-drawing test (CDT)). RESULTS: Both screening tools showed a significantly increased risk of delirium with p < 0.001 (OR 12.5, 95% [6.42; 24.4]) in SIS and p = 0.042 (OR 2.02, 95%CI [1.02; 4.03]) in CDT for existing cognitive impairment. A higher level of care (p < 0.001) and statutory care (p < 0.001, OR 5.42, 95%CI [2.34; 12.6]) also proved to be significant risk factors. The ROC curves of the two tests show AUC values of 0.741 (SIS) and 0.630 (CDT). The COP values for the SIS are 4 points with a Youden index of 0.447; for the CDT, the COP is 2 (Youden index = 0.177). CONCLUSIONS: The recording of PCI should be a central component of the preoperative geriatric assessment. The tools used are simple yet effective and can be easily implemented in routine clinical practice. By reliably identifying patients at risk, the available resources can be personalized and used in a targeted approach.

PMID: PMID: 39727814

PMCID: PMC11675788

Keywords: cognitive impairment, geriatric assessment, postoperative delirium, surgery

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Total Records Found: 6479, showing 100 per page
Title	Authors	Journal	Year	Keywords
Delirium after cardiac surgery. Incidence, phenotypes, predisposing and precipitating risk factors, and effects.	Sanson, G. Khlopenyuk, Y. Milocco, S. Sartori, M. Dreas, L. Fabiani, A.	Heart Lung	2018	Cardiac surgery Delirium Incidence Intensive care Phenotype Subsyndromal delirium
Educational Intervention on Delirium Assessment Using Confusion Assessment Method-ICU (CAM-ICU) in a General Intensive Care Unit.	Ramoo, V. Abu, H. Rai, V. Surat Singh, S. K. Baharudin, A. A. Danaee, M. Thinagaran, R. R. R.	J Clin Nurs	2018	Cam-icu Critical care nurses Delirium Delirium assessment ICU Delirium Malaysia
Delirium Burden in Patients and Family Caregivers: Development and Testing of New Instruments.	Racine, A. M. D'Aquila, M. Schmitt, E. M. Gallagher, J. Marcantonio, E. R. Jones, R. N. Inouye, S. K. Schulman-Green, D.	Gerontologist	2018
Processed electroencephalogram and evoked potential techniques for amelioration of postoperative delirium and cognitive dysfunction following non-cardiac and non-neurosurgical procedures in adults.	Punjasawadwong, Y. Chau-In, W. Laopaiboon, M. Punjasawadwong, S. Pin-On, P.	Cochrane Database of Systematic Reviews	2018
Influence of physical restraint on delirium of adult patients in ICU: A nested case–control study.	Pan, Yanbin Jiang, Zhixia Yuan, Changrong Wang, Lianhong Zhang, Jingjing Zhou, Jing Tao, Ming Quan, Mingtao Wu, Qiong	Journal of Clinical Nursing	2018	Restraint, Physical — Adverse Effects Delirium — Risk Factors Intensive Care Units Human Case Control Studies Prospective Studies Clinical Assessment Tools Length of Stay Scales Apache Data Analysis Software Chi Square Test T-Tests Multivariate Analysis Logistic Regression ROC Curve Male Female Univariate Statistics Adult Middle Age
Development of a Novel Self-administered Cognitive Assessment Tool and Normative Data for Older Adults.	Monsch, R. J. Burckhardt, A. C. Berres, M. Thomann, A. E. Ehrensperger, M. M. Steiner, L. A. Goettel, N.	J Neurosurg Anesthesiol	2018
Cooccurrence of Post-Intensive Care Syndrome Problems Among 406 Survivors of Critical Illness.	Marra, A. Pandharipande, P. P. Girard, T. D. Patel, M. B. Hughes, C. G. Jackson, J. C. Thompson, J. L. Chandrasekhar, R. Ely, E. W. Brummel, N. E.	Crit Care Med	2018
Precipitants of Delirium in Older Inpatients Admitted in Surgery for Post-Fall Hip Fracture: An Observational Study.	Levinoff, E. Try, A. Chabot, J. Lee, L. Zukor, D. Beauchet, O.	The Journal of Frailty & Aging	2018	aged delirium female hip fracture hospital patient human male postoperative complication Quebec retrospective study risk factor very elderly
Neural predisposing factors of postoperative delirium in elderly patients with femoral neck fracture.	Kyeong, S. Shin, J. E. Yang, K. H. Lee, W. S. Chung, T. S. Kim, J. J.	Sci Rep	2018
Music intervention to prevent delirium among older patients admitted to a trauma intensive care unit and a trauma orthopaedic unit.	Johnson, K. Fleury, J. McClain, D.	Intensive Crit Care Nurs	2018	Delirium Diastolic pressure Heart rate Music listening Neuroscience of music Non-pharmacologic approach Pharmacologic approach Roy Adaptation Model Systolic blood pressure
Delirium as a predictor of mortality in US Medicare beneficiaries discharged from the emergency department: a national claims-level analysis up to 12 months.	Israni, J. Lesser, A. Kent, T. Ko, K.	BMJ Open	2018	claims data delirium geriatrics mortality
An evaluation of patient-specific characteristics on attainment of target sedation in an intensive care unit.	Humphrey, M. Everhart, S. Kosmisky, D. Anderson, W. E.	Heart Lung	2018	Agitation Critical care Delirium Monitoring Rass Sedation
An assistant workforce to improve screening rates and quality of care for older patients in the emergency department: findings of a pre- post, mixed methods study.	Hullick, C. Conway, J. Higgins, I. Hewitt, J. Stewart, B. Dilworth, S. Attia, J.	BMC Geriatr	2018	Assessment, nursing Caregivers Comprehensive geriatric assessment Delirium Delirium prevention Emergency department, aged Emergency nursing Emergency services, hospital Older person Screening Standard of care
Cycling of Dexmedetomidine May Prevent Delirium After Liver Transplantation.	Hong, K. S. Kim, N. R. Song, S. H. Hong, G.	Transplant Proc	2018
Risk Factors for Postoperative Delirium After Gastrectomy in Gastric Cancer Patients.	Honda, S. Furukawa, K. Nishiwaki, N. Fujiya, K. Omori, H. Kaji, S. Makuuchi, R. Irino, T. Tanizawa, Y. Bando, E. Kawamura, T. Terashima, M.	World J Surg	2018
Factors Associated with the Effectiveness of Intravenous Administration of Chlorpromazine for Delirium in Patients with Terminal Cancer.	Hasuo, H. Kanbara, K. Fujii, R. Uchitani, K. Sakuma, H. Fukunaga, M.	J Palliat Med	2018	delirium intravenous chlorpromazine motoric subtype shock index terminal cancer
An evaluation of single question delirium screening tools in older emergency department patients.	Han, J. H. Wilson, A. Schnelle, J. F. Dittus, R. S. Wesley Ely, E.	American Journal of Emergency Medicine	2018	adult article consultation delirium diagnostic test accuracy study diagnostic value DSM-IV-TR emergency physician emergency ward female human major clinical study male mental health observational study prospective study psychiatrist scientist speech thinking
A contemporary population-based analysis of the incidence, cost, and outcomes of postoperative delirium following major urologic cancer surgeries.	Ha, A. Krasnow, R. E. Mossanen, M. Nagle, R. Hshieh, T. T. Rudolph, J. L. Chang, S. L.	Urol Oncol	2018	Costs Cystectomy Incidence Nephrectomy Outcomes Postoperative delirium
Risk Factors and Outcomes of Delirium in Older Patients Admitted to Postacute Care with and without Dementia.	Gual, N. Morandi, A. Perez, L. M. Britez, L. Burbano, P. Man, F. Inzitari, M.	Dement Geriatr Cogn Disord	2018	Crisis management Delirium Delirium superimposed on dementia Emergency department Intermediate care Risk factors Skilled nursing facilities
Frailty Assessment to Help Predict Patients at Risk of Delirium When Consulting the Emergency Department.	Giroux, M. Sirois, M. J. Boucher, V. Daoust, R. Gouin, E. Pelletier, M. Berthelot, S. Voyer, P. Emond, M.	J Emerg Med	2018	delirium emergency department frailty length of stay older adults
Performance of the French version of the 4AT for screening the elderly for delirium in the emergency department.	Gagne, A. J. Voyer, P. Boucher, V. Nadeau, A. Carmichael, P. H. Pelletier, M. Gouin, E. Berthelot, S. Daoust, R. Wilchesky, M. Richard, H. Pelletier, I. Ballard, S. Lague, A. Emond, M.`	CJEM	2018
Early rehabilitation to prevent postintensive care syndrome in patients with critical illness: a systematic review and meta-analysis	Fuke, R. Hifumi, T. Kondo, Y. Hatakeyama, J. Takei, T. Yamakawa, K. Inoue, S. Nishida, O.	BMJ Open	2018	early rehabilitation intensive care unit post-intensive care syndrome sepsis
Effects of closed-loop intravenous anesthesia guided by Bispectral Index in adult patients on emergence delirium: A randomized controlled study.	Cotoia, A. Mirabella, L. Beck, R. Matrella, P. Assenzo, V. Hazot, T. C. Cinnella, G. Liu, N. Dambrosio, M.	Minerva Anestesiol	2018	epidural catheter suture anesthetic agent atropine cisatracurium desflurane etilefrine levobupivacaine morphine neostigmine propofol remifentanil sevoflurane adult aged anesthesia article bispectral index breathing rate controlled study double blind procedure drug withdrawal emergence agitation extubation female human hypotension major clinical study male middle aged Mini Mental State Examination neuromuscular function operative blood loss positive end expiratory pressure postoperative pain prospective study randomized controlled trial scoring system titrimetry urologic surgery chirocaine diprivan effortil intrastigmina nimbex sevorane suprane ultiva
Prevalence and risk factors related to haloperidol use for delirium in adult intensive care patients: the multinational AID-ICU inception cohort study.	Collet, M. O. Caballero, J. Sonneville, R. Bozza, F. A. Nydahl, P. Schandl, A. Woien, H. Citerio, G. van den Boogaard, M. Hastbacka, J. Haenggi, M. Colpaert, K. Rose, L. Barbateskovic, M. Lange, T. Jensen, A. Krog, M. B. Egerod, I. Nibro, H. L. Wetterslev	Intensive Care Med	2018	Cohort Critical care Delirium Haloperidol Icu
Latent class analysis of the multivariate Delirium Index in long-term care settings.	Ciampi, A. Bai, C. Dyachenko, A. McCusker, J. Cole, M. G. Belzile, E.	Int Psychogeriatr	2018	Delirium Index delirium hidden Markov model latent class long-term care longitudinal old
Cognitive Decline after Delirium in Patients Undergoing Cardiac Surgery.	Brown, C. H. th Probert, J. Healy, R. Parish, M. Nomura, Y. Yamaguchi, A. Tian, J. Zehr, K. Mandal, K. Kamath, V. Neufeld, K. J. Hogue, C. W.	Anesthesiology	2018
Screening for Delirium: Development and Validation of the Buffalo Delirium Scale for Use in a Home-Based Hospice Setting.	Breier, J. M. Meier, S. T. Kerr, C. W. Wright, S. T. Grant, P. C. Depner, R. M.	Am J Hosp Palliat Care	2018	delirium end of life hospice care psychometrics
Improving Geriatric Care Processes on Two Medical-Surgical Acute Care Units: A Pilot Study.	Booth, K. A. Simmons, E. E. Viles, A. F. Gray, W. A. Kennedy, K. R. Biswal, S. H. Lowe, J. A. Xhaja, A. Kennedy, R. E. Brown, C. J. Flood, K. L.	J Healthc Qual	2018
Screening for delirium with the Intensive Care Delirium Screening Checklist (ICDSC): Symptom profile and utility of individual items in the identification of delirium dependent on the level of sedation.	Boettger, S. Meyer, R. Richter, A. Fernandez, S. F. Rudiger, A. Schubert, M. Jenewein, J. Nunez, D. G.	Palliat Support Care	2018	4th edition text revision (DSM-IV-TR) Delirium Diagnostic and Statistical Manual Intensive Care Delirium Screening Checklist (ICDSC) Richmond Agitation and Sedation Scale (RASS) intensive care unit (ICU) phenomenology
The impact of psychomotor subtypes and duration of delirium on 6-month mortality in hip-fractured elderly patients.	Bellelli, G. Carnevali, L. Corsi, M. Morandi, A. Zambon, A. Mazzola, P. Galeazzi, M. Bonfanti, A. Massariello, F. Szabo, H. Oliveri, G. Haas, J. d'Oro, L. C. Annoni, G.	Int J Geriatr Psychiatry	2018	delirium hip fracture psychomotor subtype surgery survival
Validation of the Brief Confusion Assessment Method for screening delirium in elderly medical patients in a German emergency department.	Baten, V. Busch, H. J. Busche, C. Schmid, B. Heupel-Reuter, M. Perlov, E. Brich, J. Kloppel, S.	Acad Emerg Med	2018	bCAM Delirium Emergency Department Geriatric medicine Germany Validity
Association of intensive care unit delirium with sleep disturbance and functional disability after critical illness: an observational cohort study.	Altman, M. T. Knauert, M. P. Murphy, T. E. Ahasic, A. M. Chauhan, Z. Pisani, M. A.	Ann Intensive Care	2018	Activities of daily living Critical care Delirium Disability Post-ICU Post-hospital Sleep disturbance
Impact of Delirium on Patients Hospitalized for Myocardial Infarction: a Propensity Score Analysis of The National Inpatient Sample.	Abdullah, A. Eigbire, G. Salama, A. Wahab, A. Awadalla, M. Hoefen, R. Alweis, R.	Clin Cardiol	2018	ICD-9-CM codes comorbidities “Altered mental status” “Delirium” “Myocardial Infarction
The role of geriatrician-hospitalists in the care of older adults: A retrospective cohort study.	Sinvani, L. Carney, M. Kozikowski, A. Smilios, C. Patel, V. Qiu, G. Zhang, M. Babalola, O. Kandov, Y. Rosenberg, D. Wolf-Klein, G. Pekmezaris, R.	Arch Gerontol Geriatr	2018	indwelling catheter urinary catheter benzodiazepine cholinergic receptor blocking agent aged article Charlson Comorbidity Index clinical outcome clinical practice cohort analysis comorbidity delirium documentation female geriatric care geriatrician hospital admission hospital discharge hospital readmission human length of stay major clinical study male medical staff outcome assessment patient compliance priority journal retrospective study safety tertiary care center
Clinical and laboratory characteristics associated with referral of hospitalized elderly to palliative care.	Arcanjo, S. P. Saporetti, L. A. Curiati, J. A. E. Jacob-Filho, W. Avelino-Silva, T. J.	Einstein (Sao Paulo)	2018
Intraoperative cerebral oximetry-based management for optimizing perioperative outcomes: a meta-analysis of randomized controlled trials.	Zorrilla-Vaca, A. Healy, R. Grant, M. C. Joshi, B. Rivera-Lara, L. Brown, C. Mirski, M. A.	Canadian Journal of Anesthesia	2018	ISRCTN01707446 ISRCTN23557269 NCT02155868 article cerebral oximetry clinical outcome hospitalization human incidence intensive care unit intraoperative monitoring length of stay meta analysis outcome assessment oximetry patient care patient safety postoperative cognitive dysfunction postoperative delirium priority journal randomized controlled trial (topic) systematic review
Postoperative delirium in total knee and hip arthroplasty patients: a study of perioperative modifiable risk factors.	Weinstein, S. M. Poultsides, L. Baaklini, L. R. Mörwald, E. E. Cozowicz, C. Saleh, J. N. Arrington, M. B. Poeran, J. Zubizarreta, N. Memtsoudis, S. G.	British Journal of Anaesthesia	2018	total hip prosthesis benzodiazepine derivative ketamine opiate adult aged analgesia anesthesia article comorbidity epidural anesthesia female general anesthesia hip arthroplasty hospital admission hospitalization human ICD-9 major clinical study male medical history medical record neuraxial anaesthesia observational study patient care perioperative period postoperative delirium prescription priority journal retrospective study risk factor spinal anesthesia surgical patient total knee arthroplasty
Impact of dexmedetomidine infusion during general anaesthesia on incidence of postoperative delirium in elderly patients after major non-cardiac surgery: study protocol of a randomised, double-blinded and placebo-controlled trial.	Wang, B. J. Li, C. J. Hu, J. Li, H. J. Guo, C. Wang, Z. H. Zhang, Q. C. Mu, D. L. Wang, D. X.	BMJ Open	2018	elderly intraoperative dexmedetomidine major non-cardiac surgery postoperative delirium given at academic meetings from Jiangsu Hengrui Medicine, China, and Yichang Humanwell Pharmaceutical, China. D-LM is the primary investigator of the present study, which was supported by Beijing Excellent Talent Support Program.
Can education improve clinical practice concerning delirium in older hospitalised patients? Results of a pre-test post-test study on an educational intervention for nursing staff.	van Velthuijsen, E. L. Zwakhalen, S. M. G. Warnier, R. M. J. Ambergen, T. Mulder, W. J. Verhey, F. R. J. Kempen, Gijm	BMC Med Educ	2018	Delirium Educational intervention Hospital PRECEDE model
Withdrawal versus continuation of long-term antipsychotic drug use for behavioural and psychological symptoms in older people with dementia.	Van Leeuwen, E. Petrovic, M. van Driel, M. L. De Sutter, A. I. M. Vander Stichele, R. Declercq, T. Christiaens, T.	Cochrane Database of Systematic Reviews	2018	chlorpromazine haloperidol levomepromazine lorazepam loxapine mesoridazine neuroleptic agent olanzapine perphenazine placebo risperidone thioridazine tiotixene trifluoperazine aggression agitation akathisia behavior disorder blood pressure body equilibrium cardiovascular disease cognition confusion dementia drug fatality drug megadose drug response drug safety drug withdrawal extrapyramidal symptom falling fracture heart rate human insomnia long term care low drug dose lung disease mental disease motor dysfunction nausea neurologic disease nursing home parkinsonism physical mobility primary medical care priority journal psychosis quality of life relapse restlessness review sedation side effect systematic review tardive dyskinesia treatment outcome vomiting
Delirium in the Intensive Care Unit: Incidence, risk factors, and impact on outcome.	Tilouche, N. Hassen, M. F. Ali, H. B. S. Jaoued, O. Gharbi, R. El Atrous, S.	Indian Journal of Critical Care Medicine	2018	endotracheal tube urinary catheter analgesic agent hypertensive factor midazolam steroid adult article artificial ventilation catheter removal chronic obstructive lung disease clinical evaluation conscious sedation controlled study delirium disease association disease duration female heart arrest hospital admission hospital mortality human hypertension incidence length of stay major clinical study male medical history medical intensive care unit medical staff observational study outcome assessment patient risk prospective study risk assessment risk factor Tunisia
Should This Patient Receive Prophylactic Medication to Prevent Delirium?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center.	Tess, A. V. Mattison, M. L. P. Leo, J. R. Reynolds, E. E.	Ann Intern Med	2018
Use of the CAM-ICU during daily sedation stops in mechanically ventilated patients as assessed and experienced by intensive care nurses - A mixed-methods study.	Steinseth, E. B. Hoye, S. Hov, R.	Intensive Crit Care Nurs	2018	Assessment Confusion Assessment Method for Intensive Care Unit Experiences Intensive care nurses
Risk factors and outcome of postoperative delirium after transcatheter aortic valve replacement.	Stachon, P. Kaier, K. Zirlik, A. Reinohl, J. Heidt, T. Bothe, W. Hehn, P. Zehender, M. Bode, C. von Zur Muhlen, C.	Clin Res Cardiol	2018	In-hospital mortality Outcome Postoperative delirium Transcatheter aortic valve replacement (TAVR)
Neurological Sequelae and Clinical Outcomes After Lung Transplantation.	Smith, P. J. Stonerock, G. L. Ingle, K. K. Saulino, C. K. Hoffman, B. Wasserman, B. Blumenthal, J. A. Palmer, S. M. Klapper, J. A. Hartwig, M. G. Esposito, V. R. Snyder, L. D.	Transplant Direct	2018
Comparison of Ketamine- Versus Nonketamine-Based Sedation on Delirium and Coma in the Intensive Care Unit.	Shurtleff, V. Radosevich, J. J. Patanwala, A. E.	Journal of Intensive Care Medicine	2018	adult analgesia article artificial ventilation cohort analysis coma controlled clinical trial controlled study delirium drug therapy female human incidence infusion intensive care unit major clinical study male outcome assessment retrospective study sedation United States university hospital ventilated patient dexmedetomidine ketamine propofol sedative agent
Postoperative delirium in elderly patients with critical limb ischemia undergoing major leg amputation: a retrospective study.	Shin, Y. H. Yoon, J. S. Jeon, H. J. Kim, Y. B. Kim, Y. S. Park, J. Y.	Korean J Anesthesiol	2018	Amputation Delirium Elderly patients Ischemia Leg
The validity and reliability of the Arabic version of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU): A prospective cohort study	Selim, A. Kandeel, N. Elokl, M. Khater, M. S. Saleh, A. N. Bustami, R. Ely, E. W.	Int J Nurs Stud	2018	Delirium Diagnosis Intensive care unit Sensitivity and specificity
Validation of Caregiver-Centered Delirium Detection Tools: A Systematic Review.	Rosgen, B. Krewulak, K. Demiantschuk, D. Ely, E. W. Davidson, J. E. Stelfox, H. T. Fiest, K. M.	J Am Geriatr Soc	2018	caregiver delirium family hospital screening
Study protocol to assess the effectiveness and safety of a flexible family visitation model for delirium prevention in adult intensive care units: a cluster-randomised, crossover trial (The ICU Visits Study).	Rosa, R. G. Falavigna, M. Robinson, C. C. da Silva, D. B. Kochhann, R. de Moura, R. M. Santos, M. M. S. Sganzerla, D. Giordani, N. E. Eugenio, C. Ribeiro, T. Cavalcanti, A. B. Bozza, F. Azevedo, L. C. P. Machado, F. R. Salluh, J. I. F. Pellegrini, J. A. S	BMJ Open	2018	critical care delirium family health personnel intensive care unit
Attention, arousal and other rapid bedside screening instruments for delirium in older patients: a systematic review of test accuracy studies.	Quispel-Aggenbach, D. W. P. Holtman, G. A. Zwartjes, Haht Zuidema, S. U. Luijendijk, H. J.	Age & Ageing	2018
Use of haloperidol versus atypical antipsychotics and risk of in-hospital death in patients with acute myocardial infarction: Cohort study	Park, Y. Bateman, B. T. Kim, D. H. Hernandez-Diaz, S. Patorno, E. Glynn, R. J. Mogun, H. Huybrechts, K. F.	BMJ	2018	acetylsalicylic acid antiarrhythmic agent anticoagulant agent atypical antipsychotic agent benzodiazepine derivative haloperidol heparin nitric acid derivative olanzapine opiate quetiapine risperidone acute heart infarction adult aged article Caucasian Charlson Comorbidity Index cohort analysis comorbidity controlled study delirium dementia drug fatality drug safety female hazard ratio heart failure high risk patient hospital admission hospital discharge hospital mortality human intensive care unit intention to treat analysis length of stay major clinical study male non ST segment elevation myocardial infarction nursing home percutaneous coronary intervention priority journal propensity score risk factor sensitivity analysis ST segment elevation myocardial infarction survival rate treatment duration United States very elderly
Postictal delirium and violent behavior in patients with post-neurosurgical epilepsy.	Oueslati, B. Fekih-Romdhane, F. Ridha, R.	World Neurosurg	2018	epilepsy neurosurgery postictal delirium violence
Factor Analysis of Delirium in Elderly, Using the Korean Version of Delirium Rating Scale-Revised-98.	Noh, G. Kwon, I. Lee, M. Ahn, S. H. Kim, J. L.	Psychiatry Investigation	2018	Aged Delirium Factor analysis Statistical
Flexible Versus Restrictive Visiting Policies in ICUs: A Systematic Review and Meta-Analysis.	Nassar Junior, A. P. Besen, Bamp Robinson, C. C. Falavigna, M. Teixeira, C. Rosa, R. G.	Crit Care Med	2018
Effectiveness of non-pharmacological strategies for managing delirium in hospitalized postoperative adults: An umbrella review protocol.	McNeil, J. Denis, A. M. Michel, U. Concert, C. M.	JBI Database of Systematic Reviews and Implementation Reports	2018	adult clinical effectiveness clinical protocol conservative treatment data analysis delirium hospital patient human outcome assessment patient selection postoperative period review study design systematic review
Genome-wide association identifies a novel locus for delirium risk.	McCoy, T. H. Hart, K. Pellegrini, A. Perlis, R. H.	Neurobiology of Aging	2018	adult article attention biobank consultation controlled study delirium electronic health record female genetic association genetic variation genome-wide association study human major clinical study male Massachusetts phenotype psychiatry university hospital endogenous compound interleukin derivative
Risk factors for postoperative delirium in patients undergoing free flap reconstruction for oral cancer.	Makiguchi, T. Yokoo, S. Kurihara, J.	Int J Oral Maxillofac Surg	2018	delirium free flap reconstruction oral cancer risk factors
Risk factors for mortality in elderly patients with hip fractures: a meta-analysis of 18 studies.	Liu, Y. Wang, Z. Xiao, W.	Aging Clin Exp Res	2018	Elderly Hip fracture Meta-analysis Mortality Risk factor
Inflammatory markers in postoperative delirium (POD) and cognitive dysfunction (POCD): A meta-analysis of observational studies.	Liu, X. Yu, Y. Zhu, S.	PLoS One	2018
Systematic review of prediction models for delirium in the older adult inpatient.	Lindroth, H. Bratzke, L. Purvis, S. Brown, R. Coburn, M. Mrkobrada, M. Chan, M. T. V. Davis, D. H. J. Pandharipande, P. Carlsson, C. M. Sanders, R. D.	BMJ Open	2018	delirium geriatric medicine statistic
Age is the Most Significantly Associated Risk Factor with the Development of Delirium in Patients Hospitalized for More Than Five Days in Surgical Wards: Retrospective Cohort Study.	Kubota K, Suzuki A, Ohde S, Yamada U, Hosaka T, Okuno F, Fujitani I, Koitabashi A, Shimada G, Kishida A	Annals of surgery	2017	nitrogen urea adult age aged article cerebrovascular disease cohort analysis delirium female hospital patient human immobilization intensive care length of stay major clinical study male mortality rate outcome assessment pain priority journal retrospective study risk factor surgical ward urea nitrogen blood level
Reduced ex vivo release of pro-inflammatory cytokines and elevated plasma interleukin-6 are inflammatory signatures of post-stroke delirium.	Kowalska, K. Klimiec, E. Weglarczyk, K. Pera, J. Slowik, A. Siedlar, M. Dziedzic, T.	J Neuroinflammation	2018	Cytokines Delirium Inflammation Stroke
Parkinson's disease-related non-motor features as risk factors for post-operative delirium in spinal surgery.	Kim, K. H. Kang, S. Y. Shin, D. A. Yi, S. Ha, Y. Kim, K. N. Sohn, Y. H. Lee, P. H.	PLoS One	2018
Relationships between markers of neurologic and endothelial injury during critical illness and long-term cognitive impairment and disability.	Hughes, C. G. Patel, M. B. Brummel, N. E. Thompson, J. L. McNeil, J. B. Pandharipande, P. P. Jackson, J. C. Chandrasekhar, R. Ware, L. B. Ely, E. W. Girard, T. D.	Intensive Care Medicine	2018	NCT00392795 biological marker brain derived neurotrophic factor cell adhesion molecule endothelial leukocyte adhesion molecule 1 interleukin 6 protein S100B ubiquitin thiolesterase adult aged APACHE article blood brain barrier cognitive defect cohort analysis critical illness critically ill patient daily life activity diagnostic accuracy disability disease association disease severity endothelium injury enzyme linked immunosorbent assay executive function female follow up hospital admission hospital discharge human intensive care unit long term care major clinical study male middle aged neurologic disease outcome assessment prospective study respiratory failure shock survivor
Incidence, Risk Factors, and Sequelae of Post-kidney Transplant Delirium.	Haugen, C. E. Mountford, A. Warsame, F. Berkowitz, R. Bae, S. G. Thomas A Brown, C. H. th Brennan, D. C. Neufeld, K. J. Carlson, M. C. Segev, D. L. McAdams-DeMarco, M.	J Am Soc Nephrol	2018	clinical epidemiology geriatric nephrology kidney transplantation transplant outcomes
Evaluation of an Intervention With Nurses for Delirium Detection After Cardiac Surgery.	Fraser, V. Cossette, S. Mailhot, T. Brisebois, A. Dubé, V.	Worldviews on evidence-based nursing	2018	adult Canada cardiovascular surgery checklist delirium devices female human information processing intensive care unit male mass screening nursing organization and management procedures questionnaire standards tertiary care center
Delirium clinical motor subtypes: a narrative review of the literature and insights from neurobiology.	FitzGerald JM	Aging & mental health	2017	Screening and diagnosis delirium mental health mental health assessments research methods
Are antipsychotics effective for the prevention of postoperative delirium?	Castro, V. Guinguis, R. Carrasco, M.	Medwave	2018
Measuring mobility in older hospital patients with cognitive impairment using the de Morton Mobility Index.	Braun, T. Gruneberg, C. Thiel, C. Schulz, R. J.	BMC Geriatr	2018	Dementia Geriatric assessment Mobility limitation Outcome assessment Physiotherapy Psychometrics Rehabilitation de Morton Mobility Index
Haloperidol for delirium in critically ill patients – protocol for a systematic review.	Barbateskovic, M. Kraus, S. R. Collet, M. O. Mathiesen, O. Jakobsen, J. C. Perner, A. Wetterslev, J.	Acta Anaesthesiol Scand	2018	haloperidol placebo article critically ill patient data analysis data extraction data synthesis delirium drug efficacy human information processing information retrieval outcome assessment priority journal systematic review
Dexmedetomidine vs morphine and midazolam in the prevention and treatment of delirium after adult cardiac surgery; a randomized, double-blinded clinical trial.	Azeem, T. M. A. Yosif, N. E. Alansary, A. M. Esmat, I. M. Mohamed, A. K.	Saudi J Anaesth	2018	Dexmedetomidine midazolam morphine postoperative delirium
Psychometric properties of the Arabic version of the confusion assessment method for the intensive care unit (CAM-ICU).	Aljuaid, M. H. Deeb, A. M. Dbsawy, M. Alsayegh, D. Alotaibi, M. Arabi, Y. M.	BMC Psychiatry	2018	Arabic Cam-icu Cognition Critical care Delirium Geriatric Inattention Mechanical ventilation
Postoperative delirium, learning, and anesthetic neurotoxicity: Some perspectives and directions.	Mutch, W. A. El-Gabalawy, R. M. Graham, M. R.	Frontiers in Neurology	2018	adult aged animal experiment animal model article classification clinical trial (topic) congenital malformation female intraoperative monitoring learning male neurotoxicity nonhuman peroperative complication postoperative cognitive dysfunction postoperative delirium primate surgery biological product
Designing a nurse-delivered delirium bundle: What intensive care unit staff, survivors, and their families think?	Bannon, L. McGaughey, J. Clarke, M. McAuley, D. F. Blackwood, B.	Aust Crit Care	2018	Delirium Focus groups Non-pharmacological Perceptions
The 2014 updated version of the Confusion Assessment Method for the Intensive Care Unit compared to the 5th version of the Diagnostic and Statistical Manual of Mental Disorders and other current methods used by intensivists.	Chanques, G. Ely, E. W. Garnier, O. Perrigault, F. Eloi, A. Carr, J. Rowan, C. M. Prades, A. de Jong, A. Moritz-Gasser, S. Molinari, N. Jaber, S.	Ann Intensive Care	2018	Critical care Delirium Intensive care unit
Effect of a 24-h extended visiting policy on delirium in critically ill patients.	Westphal, G. A. Moerschberger, M. S. Vollmann, D. D. Inacio, A. C. Machado, M. C. Sperotto, G. Cavalcanti, A. B. Koenig, A.	Intensive Care Medicine	2018
Effect of Sedation Regimen on Weaning from Mechanical Ventilation in the Intensive Care Unit.	Nunes, S. L. Forsberg, S. Blomqvist, H. Berggren, L. Sorberg, M. Sarapohja, T. Wickerts, C. J.	Clin Drug Investig	2018
Validation of the korean version of the delirium motor subtype scale.	Kim, H. Lee, M. Kwon, I. S. Kim, J. L.	Psychiatry Investigation	2018	aged alertness apathy article brain injury consultation delirium Delirium Motor Subtype Scale Delirium Rating Scale Delirium Symptom Interview drug intoxication endocrine disease female human Korean (people) Korean version of the Delirium Rating Scale Revised 98 lethargy major clinical study male medical information motor dysfunction assessment neoplasm prospective study reliability restlessness seizure speech disorder validation study
e-Screening revolution: A novel approach to developing a delirium screening tool in the intensive care unit.	Eeles, E. Gunn, H. Sutt, A. L. Pinsker, D. Flaws, D. Jarrett, P. Lye, I. Fraser, J. F.	Australasian Journal on Ageing	2018	delirium diagnostic techniques intensive care units mobile applications neurological screening
Sedation Intensity in the First 48 Hours of Mechanical Ventilation and 180-Day Mortality: A Multinational Prospective Longitudinal Cohort Study.	Shehabi, Y. Bellomo, R. Kadiman, S. Ti, L. K. Howe, B. Reade, M. C. Khoo, T. M. Alias, A. Wong, Y. L. Mukhopadhyay, A. McArthur, C. Seppelt, I. Webb, S. A. Green, M. Bailey, M. J.	Crit Care Med	2018
Screening for delirium with the Intensive Care Delirium Screening Checklist (ICDSC): a re-evaluation of the threshold for delirium.	Boettger, S. Garcia Nunez, D. Meyer, R. Richter, A. Rudiger, A. Schubert, M. Jenewein, J.	Swiss Medical Weekly	2018
Risk Factors of Postoperative Delirium in the Intensive Care Unit After Liver Transplantation.	Lee, H. Oh, S. Y. Yu, J. H. Kim, J. Yoon, S. Ryu, H. G.	World J Surg	2018
Risk Factors for Postoperative Delirium After Deep Brain Stimulation Surgery for Parkinson's Disease.	Tanaka, M. Tani, N. Maruo, T. Oshino, S. Hosomi, K. Saitoh, Y. Kishima, H.	World Neurosurg	2018	Deep Brain Stimulation Parkinson’s Disease Postoperative Delirium Risk Factor
The relationship of delirium and risk factors in cardiology intensive care unit patients with the nursing workload.	Ozturk Birge, A. Beduk, T.	J Clin Nurs	2018	Critical Care Intensive Care Management Medical Nursing Nursing Risk Assessment
Protocol for a single-centre prospective observational study of postoperative delirium following total joint arthroplasties among South East Asians.	Abdullah, H. R. Tan, S. R. Lee, S. J. Bin Abd Razak, H. R. Seet, R. H. Ying, H. Sethi, E. Sim, E. Y.	BMJ Open	2018	delirium incidence postoperative total joint arthroplasty
Preoperative statins are associated with a reduced risk of postoperative delirium following vascular surgery.	Lee, D. S. Lee, M. Y. Park, C. M. Kim, D. I. Kim, Y. W. Park, Y. J.	PLoS One	2018
Predisposing and precipitating factors for delirium in community-dwelling older adults admitted to hospital with this condition: A prospective case series.	Magny, E. Le Petitcorps, H. Pociumban, M. Bouksani-Kacher, Z. Pautas, É Belmin, J. Bastuji-Garin, S. Lafuente-Lafuente, C.	PLoS One	2018	aged article cognitive defect community care dehydration delirium disease predisposition electrolyte disturbance emergency care female geriatric care geriatrician hospital admission human hyponatremia lung infection major clinical study male mental health neurologic disease patient assessment personalized medicine prospective study urinary tract infection very elderly
Predicting excess cost for older inpatients with clinical complexity: A retrospective cohort study examining cognition, comorbidities and complications	Bail, K. Draper, B. Berry, H. Karmel, R. Goss, J.	PLoS One	2018	adult age aged article Australia cognition cohort analysis comorbidity decubitus delirium dementia disease severity female hospital admission hospital patient hospitalization cost human length of stay linear regression analysis major clinical study male nursing care pneumonia prediction public hospital retrospective study sex urinary tract infection
Pilot Study of a Two-Step Delirium Detection Protocol Administered By Certified Nursing Assistants, Physicians, and Registered Nurses.	Fick, D. M. Inouye, S. K. McDermott, C. Zhou, W. Ngo, L. Gallagher, J. McDowell, J. Penrod, J. Siuta, J. Covaleski, T. Marcantonio, E. R.	J Gerontol Nurs	2018
Perioperative hyperglycaemia and neurocognitive outcome after surgery: a systematic review.	Hermanides, J. Qeva, E. Preckel, B. Bilotta, F.	Minerva Anestesiol	2018
Low-dose Nocturnal Dexmedetomidine Prevents ICU Delirium: A Randomized, Placebo-controlled Trial.	Skrobik, Y. Duprey, M. S. Hill, N. S. Devlin, J. W.	Am J Respir Crit Care Med	2018	delirium, sleep, intensive care, dexmedetomidine, randomized controlled trial
Low peripheral levels of insulin growth factor-1 are associated with high incidence of delirium among elderly patients: A systematic review and meta-analysis.	Li, D. J. Tseng, P. T. Stubbs, B. Chen, T. Y. Lin, P. Y. Chen, S. L. Thompson, T. Adamis, D. Chu, C. S.	Arch Gerontol Geriatr	2018	Biomarker Delirium Elderly Igf-1 Meta-analysis
Is anemia associated with cognitive impairment and delirium among older acute surgical patients?	Myint, P. K. Owen, S. McCarthy, K. Pearce, L. Moug, S. J. Stechman, M. J. Hewitt, J. Carter, B.	Geriatrics & Gerontology International	2018	anemia cognitive impairment delirium older surgical patients
Intraoperative Sedation With Dexmedetomidine is Superior to Propofol for Elderly Patients Undergoing Hip Arthroplasty: A Prospective Randomized Controlled Study.	Mei, B. Meng, G. Xu, G. Cheng, X. Chen, S. Zhang, Y. Zhang, M. Liu, X. Gu, E.	Clin J Pain	2018
Infrared pupillometry helps to detect and predict delirium in the post-anesthesia care unit.	Yang E, Kreuzer M, Hesse S, Davari P, Lee SC, García PS	Journal of clinical monitoring and computing	2017	PLR-200 pupillometer adult aged article clinical article confusion assessment method for the intensive care unit score delirium female general anesthesia human informed consent infrared pupillometry male observational study priority journal prospective study pupil pupillometry receiver operating characteristic recovery room scoring system
Influence of Physical Restraint on Delirium of Adult Patients in ICU: A Nested Case-Control Study.	Pan, Y. Jiang, Z. Changrong, Y. Wang, L. Zhang, J. Zhou, J. Tao, M. Quan, M. Wu, Q.	J Clin Nurs	2018	Delirium Intensive Care Unit Nested Case-control Study Restraint, Physical
Incidence of delirium in the Canadian emergency department and its consequences on hospital length of stay: A prospective observational multicentre cohort study.	Émond, M. Boucher, V. Carmichael, P. H. Voyer, P. Pelletier, M. Gouin, É Daoust, R. Berthelot, S. Lamontagne, M. E. Morin, M. Lemire, S. Minh Vu, T. T. Nadeau, A. Rheault, M. Juneau, L. Le Sage, N. Lee, J.	BMJ Open	2018	aged American article clinical assessment cohort analysis controlled study crowding (area) delirium emergency ward feedback system female functional status human incidence length of stay major clinical study male multicenter study multivariate analysis prospective study telephone interview
Impact of timing and duration of postoperative delirium: a retrospective observational study	Lee, H. Ju, J. W. Oh, S. Y. Kim, J. Jung, C. W. Ryu, H. G.	Surgery	2018
Frequency and risk factors for subsyndromal delirium in an intensive care unit.	Yamada, C. Iwawaki, Y. Harada, K. Fukui, M. Morimoto, M. Yamanaka, R.	Intensive Crit Care Nurs	2018	Delirium Intensive Care Delirium Screening Checklist (ICDSC) scores Intensive care unit (ICU) Subsyndromal delirium (SSD)