What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Predictors of post-stroke delirium incidence and duration: results of a prospective observational study using high frequency delirium screening
- Authors
- Fleischmann, R. Andrasch, T. Warwas, S. Kunz, R. Gross, S. Witt, C. Ruhnau, J. Vogelgesang, A. Ulm, L. Mengel, A. von Sarnowski, B.
- Year
- 2022
- Journal
- Int J Stroke
- Abstract
BackgroundPost-stroke delirium (PSD) is a modifiable predictor for inferior outcome in stroke. Knowledge of its risk factors would facilitate clinical management of affected patients, but recently updated national guidelines consider available evidence insufficient.AimsThe study aims to establish risk factors for PSD incidence and duration using high-frequency screening.MethodsWe prospectively investigated patients with ischemic stroke admitted within 24 hours. Patients were screened twice daily for the presence of PSD throughout the treatment period. Sociodemographic, treatment-related and neuroimaging characteristics were evaluated as predictors of either PSD incidence (odds ratios, OR) or duration (PSD days/unit of the predictor, b) in logistic and linear regression models, respectively.ResultsPSD occurred in 55/141 patients (age 73.8±10.4 years, 61 female, NIHSS 6.4±6.5). Age (OR=1.06 [95%CI: 1.02-1.10], b=0.08 [95%CI: 0.04-0.13]) and male gender (b=0.99 [95%CI: -1.93-0.05]) were significant non-modifiable risk factors. In a multivariable model adjusted for age and gender, presence of pain (OR(mvar)=1.75 [95%CI: 1.12-2.74], b(mvar)=0.49 [95%CI: 0.19-0.81]), urinary catheter (OR(mvar)=3.16 [95%CI: 1.10-9.14], b(mvar)=1.03 [95%CI: 0.01-2.07]), intravenous line (b(mvar)=0.36 [95%CI: 0.16-0.57]) and post-stroke infection (PSI; OR(mvar)=4.43 [95%CI: 1.09-18.01], b(mvar)=1.60 [95%CI: 0.42-2.78]) were predictors for PSD incidence and duration, respectively. PSD (OR(mvar)=3.53 [95%:CI: 1.48-5.57]) and PSI (OR(mvar)=5.29 [95%:CI: 2.92-7.66]) independently predicted inferior outcome. Insular and basal ganglia lesions increased the PSD risk about four- to eightfold.Discussion/ConclusionThis study yielded modifiable risk factors, the management of which may ameliorate the negative impact PSD has on outcome (e.g. pain, medical devices, infection). Basal ganglia or insular lesions might increase awareness for PSD.Clinical Trial Registrationhttp://www.clinicaltrials.gov, ID: NCT03930719.
- PMID
- Keywords
Acute stroke therapy
Risk factors
cognitive impairment
ischemic stroke
pain
post-stroke delirium
post-stroke infection
- Page(s)
- Volume
- Issue
Title | Authors | Journal | Year | Keywords |
---|---|---|---|---|
Have you SCAND MMe Please? A framework to prevent harm during acute hospitalisation of older persons: A retrospective audit. | Redley, B. Baker, T. | Journal of Clinical Nursing | 2019 |
acute disease |
Low-Dose Ketamine Infusion to Decrease Postoperative Delirium for Spinal Fusion Patients. | Plyler, S. S. Muckler, V. C. Titch, J. F. Gupta, D. K. Rice, A. N. | J Perianesth Nurs | 2019 |
3d-cam |
Nurses' experiences of caring for older patients afflicted by delirium in a neurological department. | Kristiansen, S. Konradsen, H. Beck, M. | Journal of Clinical Nursing | 2019 |
adult |
Association of Delirium Response and Safety of Pharmacological Interventions for the Management and Prevention of Delirium: A Network Meta-analysis. | Wu, Y. C. Tseng, P. T. Tu, Y. K. Hsu, C. Y. Liang, C. S. Yeh, T. C. Chen, T. Y. Chu, C. S. Matsuoka, Y. J. Stubbs, B. Carvalho, A. F. Wada, S. Lin, P. Y. Chen, Y. W. Su, K. P. | JAMA Psychiatry | 2019 | |
Effect of electroencephalography-guided anesthetic administration on postoperative delirium among older adults undergoing major surgery the engages randomized clinical trial. | Wildes, T. S. Mickle, A. M. Abdallah, A. B. Maybrier, H. R. Oberhaus, J. Budelier, T. P. Kronzer, A. McKinnon, S. L. Park, D. Torres, B. A. Graetz, T. J. Emmert, D. A. Palanca, B. J. Goswami, S. Jordan, K. Lin, N. Fritz, B. A. Stevens, T. W. Jacobsohn, E. | JAMA | 2019 |
NCT02241655 |
Perioperative Epidural Use and Risk of Delirium in Surgical Patients: A Secondary Analysis of the PODCAST Trial. | Vlisides, P. E. Thompson, A. Kunkler, B. S. Maybrier, H. R. Avidan, M. S. Mashour, G. A. | Anesth Analg | 2019 | |
Effect of Intravenous Acetaminophen vs Placebo Combined with Propofol or Dexmedetomidine on Postoperative Delirium among Older Patients Following Cardiac Surgery: The DEXACET Randomized Clinical Trial. | Subramaniam, B. Shankar, P. Shaefi, S. Mueller, A. O'Gara, B. Banner-Goodspeed, V. Gallagher, J. Gasangwa, D. Patxot, M. Packiasabapathy, S. Mathur, P. Eikermann, M. Talmor, D. Marcantonio, E. R. | JAMA | 2019 |
NCT02546765 |
The use of a screening scale improves the recognition of delirium in older patients after cardiac surgery - a retrospective observational study. | Smulter, N. Claesson Lingehall, H. Gustafson, Y. Olofsson, B. Engstrom, K. G. | J Clin Nurs | 2019 |
Assessments scales |
Incidence and predictors of postoperative delirium in the older acute care surgery population: a prospective study. | Saravana-Bawan, B. Warkentin, L. M. Rucker, D. Carr, F. Churchill, T. A. Khadaroo, R. G. | Canadian Journal of Surgery | 2019 |
aged |
Association of Duration of Surgery With Postoperative Delirium Among Patients Receiving Hip Fracture Repair. | Ravi, B. Pincus, D. Choi, S. Jenkinson, R. Wasserstein, D. N. Redelmeier, D. A. | JAMA Netw Open | 2019 | |
Depression Predicts Delirium After Coronary Artery Bypass Graft Surgery Independent of Cognitive Impairment and Cerebrovascular Disease: An Analysis of the Neuropsychiatric Outcomes After Heart Surgery Study. | Oldham, M. A. Hawkins, K. A. Lin, I. H. Deng, Y. Hao, Q. Scoutt, L. M. Yuh, D. D. Lee, H. B. | American Journal of Geriatric Psychiatry | 2019 |
aged |
Accuracy of the Delirium Observational Screening Scale (DOS) as a screening tool for delirium in patients with advanced cancer. | Neefjes, E. C. W. van der Vorst, Mjdl Boddaert, M. S. A. Verdegaal, Batt Beeker, A. Teunissen, S. C. C. Beekman, A. T. F. Zuurmond, W. W. A. Berkhof, J. Verheul, H. M. W. | BMC Cancer | 2019 |
Delirium |
The impact of intravenous isotonic and hypotonic maintenance fluid on the risk of delirium in adult postoperative patients: retrospective before-after observational study. | Nagae, M. Egi, M. Furushima, N. Okada, M. Makino, S. Mizobuchi, S. | J Anesth | 2019 |
Delirium |
Association between delirium, adverse clinical events and functional outcomes in older patients admitted to rehabilitation settings after a hip fracture: A multicenter retrospective cohort study. | Morandi, A. Mazzone, A. Bernardini, B. Suardi, T. Prina, R. Pozzi, C. Gentile, S. Trabucchi, M. Bellelli, G. | Geriatrics & Gerontology International | 2019 |
aged |
Handover of anesthesia care is associated with an increased risk of delirium in elderly after major noncardiac surgery: results of a secondary analysis. | Liu, G. Y. Su, X. Meng, Z. T. Cui, F. Li, H. L. Zhu, S. N. Wang, D. X. | J Anesth | 2019 |
Delirium |
Undiagnosed delirium is frequent and difficult to predict: Results from a prevalence survey of a tertiary hospital. | Lange, P. W. Lamanna, M. Watson, R. Maier, A. B. | J Clin Nurs | 2019 |
Undiagnosed delirium |