Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Preoperative prognostic nutritional index is useful factor for predicting postoperative delirium after primary total joint arthroplasty
Authors
Chen, J. Zheng, C. Zhong, J. Zhao, G. Shi, J. Huang, G. Wei, Y. Wang, S. Yu, J. Xia, J.
Year
2021
Journal
BMC Musculoskelet Disord
Abstract

BACKGROUND: Postoperative delirium (PD), as an acute brain failure, is widely reported as a very common postoperative complication, and it is closely associated with increased morbidity and mortality. Recently, malnutrition is reported as one of the risk factors for PD. The prognostic nutritional index (PNI) is a simple method for nutritional evaluation. However, few studies have discussed the effectiveness of PNI as a nutritional assessment in predicting PD after primary total joint arthroplasty (TJA). The aim of this study is to investigate potential risk factors including PNI for PD following primary TJA. METHODS: A retrospective analysis of 994 patients was performed to identify risk factors associated with PD after primary TJA by using univariate and multivariate analyses. A receiver operating characteristic curve and the area under the curve were applied to evaluate the significant results of the multivariate analysis and the optimal cutoff value (CV). RESULTS: Postoperatively, sixty-seven patients (67/994, 6.7 %) experienced PD. Univariate analysis demonstrated that operative time, duration of anesthesia, age, hypertension, serum albumin, and PNI differed between the PD and non-PD groups (P < 0.05). Multivariate logistic regression analysis showed that the preoperative PNI (odds ratio [OR]: 0.908; 95 % confidence interval [CI]: 0.840-0.983; CV: 47.05), age of patients (OR: 1.055; 95 % CI: 1.024-1.087; CV: 73.5 years), and hypertension (OR: 1.798; 95 % CI: 1.047-3.086), were independently associated with PD (P < 0.05). CONCLUSIONS: A low preoperative PNI associated with malnutrition was demonstrated to be an independent risk factor for PD following primary TJA. Patients with preoperative low PNI should be cautioned and provided with adequate nutritional intervention to reduce postoperative PD.

PMID

PMC8436555

Keywords

Aged
Arthroplasty
*Delirium/diagnosis/epidemiology/etiology
Humans
*Nutrition Assessment
Prognosis
Retrospective Studies
Malnutrition
Postoperative delirium
Prognostic nutritional index
Risk factor
Total joint arthroplasty

Page(s)
Issue
1

Search:
Total Records Found: 6272, showing 100 per page
TitleAuthorsJournalYearKeywords
Rate and risk factors for a hyperactivity delirium in patients with aneurysmal subarachnoid haemorrhage. Sauvigny, T. Mohme, M. Grensemann, J. Duhrsen, L. Regelsberger, J. Kluge, S. Schmidt, N. O. Westphal, M. Czorlich, P. Neurosurg Rev 2018

Delirium
Hydrocephalus
Microsurgical clipping
Neurocritical care
Rass
Subarachnoid haemorrhage

Delirium in Postoperative Patients Admitted to the Intensive Care Unit. Romanauski, T. R. Martin, E. E. Sprung, J. Martin, D. P. Schroeder, D. R. Weingarten, T. N. Am Surg 2018

Adult
Aged
Delirium/*epidemiology
Female
Humans
*Intensive Care Units
International Classification of Diseases
Length of Stay
Male
Middle Aged
Postoperative Complications/*epidemiology
Retrospective Studies
Risk Factors
Surgical Procedures, Operative/*adverse effects/statistics & numerical data

Degree of implementation of preventive strategies for post-ICU syndrome: Multi-centre, observational study in Spain. Raurell-Torreda, M. Arias-Rivera, S. Marti, J. D. Frade-Mera, M. J. Zaragoza-Garcia, I. Gallart, E. Velasco-Sanz, T. R. San Jose-Arribas, A. Blazquez-Martinez, E. Enferm Intensiva 2018

Critical illness
Early mobility
Enfermedad critica
Enfermeria
Intensive Care Units
Movilizacion precoz
Nursing
Physical therapy
Rehabilitacion
Rehabilitation
Terapia fisica
Unidades de Cuidados Intensivos

Surgical delay is a risk factor of delirium in hip fracture patients with mild-moderate cognitive impairment. Pioli, G. Bendini, C. Giusti, A. Pignedoli, P. Cappa, M. Iotti, E. Ferri, M. A. Bergonzini, E. Sabetta, E. Aging Clin Exp Res 2018

Delirium
Dementia
Hip fracture
Orthogeriatric
Osteoporosis

Predictors of Delirium Development in Older Medical Inpatients: Readily Identifiable Factors at Admission. O’Regan, Niamh A. Fitzgerald, James Adamis, Dimitrios Molloy, David William Meagher, David Timmons, Suzanne Montero-Odasso, Manuel Journal of Alzheimer's Disease 2018
Processed Electroencephalogram Monitoring and Postoperative Delirium: A Systematic Review and Meta-analysis. MacKenzie, K. K. Britt-Spells, A. M. Sands, L. P. Leung, J. M. Anesthesiology 2018
The influence of oxygen delivery during cardiopulmonary bypass on the incidence of delirium in CABG patients; a retrospective study Leenders, J. Overdevest, E. van Straten, B. Golab, H. Perfusion 2018

Cabg
cardiopulmonary bypass
delirium
oxygen delivery

Safety of brotizolam in hospitalized patients. Lavon, O. Bejel, S. European Journal of Clinical Pharmacology 2018

benzodiazepine derivative
brotizolam
aged
article
artificial ventilation
cohort analysis
comorbidity
controlled study
delirium
drug safety
falling
female
hospital patient
human
insomnia
internal medicine
major clinical study
male
multivariate logistic regression analysis
outcome assessment
prescription
priority journal
respiratory tract disease
retrospective study
risk benefit analysis
risk factor
side effect

Early delirium after cardiac surgery: An analysis of incidence and risk factors in elderly (≥65 years) and very elderly (≥80 years) patients. Kotfis, K. Szylińska, A. Listewnik, M. Strzelbicka, M. Brykczyński, M. Rotter, I. Żukowski, M. Clinical Interventions in Aging 2018

creatinine
age
aged
artery disease
article
atrial fibrillation
clinical outcome
cohort analysis
controlled study
creatinine blood level
delirium
diabetes mellitus
female
heart ejection fraction
heart surgery
hospitalization
human
incidence
intensive care unit
major clinical study
male
mortality rate
pneumonia
postoperative complication
postoperative period
prospective study
retrospective study
risk factor
tertiary care center
very elderly

ICU delirium - a diagnostic and therapeutic challenge in the intensive care unit. Kotfis, K. Marra, A. Ely, E. W. Anaesthesiol Intensive Ther 2018

Cam-icu
Icu
critical care
delirium
monitoring

Melatonin and sleep in preventing hospitalized delirium: A randomized clinical trial. Jaiswal, S. J. McCarthy, T. J. Wineinger, N. E. Kang, D. Y. Song, J. Garcia, S. van Niekerk, C. J. Lu, C. Y. Loeks, M. Owens, R. L. Am J Med 2018

Delirium
Melatonin
Sleep

Intraoperative ketamine administration to prevent delirium or postoperative cognitive dysfunction: A systematic review and meta-analysis. Hovaguimian, F. Tschopp, C. Beck-Schimmer, B. Puhan, M. Acta Anaesthesiol Scand 2018

cognitive dysfunction
ketamine
meta-analysis
postoperative delirium

The use of clonidine in elderly patients with delirium; pharmacokinetics and hemodynamic responses. Hov, K. R. Neerland, B. E. Andersen, A. M. Undseth, O. Wyller, V. B. MacLullich, A. M. J. Skovlund, E. Qvigstad, E. Wyller, T. B. BMC Pharmacol Toxicol 2018

Clonidine
Delirium
Pharmacokinetic
Rct

Delirium's Arousal Subtypes and Their Relationship with 6-Month Functional Status and Cognition. Han, J. H. Hayhurst, C. J. Chandrasekhar, R. Hughes, C. G. Vasilevskis, E. E. Wilson, J. E. Schnelle, J. F. Dittus, R. S. Ely, E. W. Psychosomatics 2018

aged
arousal
article
cognitive defect
cohort analysis
controlled study
daily life activity
emergency ward
female
functional status
hospital patient
hospitalization
human
major clinical study
male
multiple linear regression analysis
prospective study
questionnaire
Richmond Agitation Sedation Scale
secondary analysis

Intraoperative electroencephalogram suppression at lower volatile anaesthetic concentrations predicts postoperative delirium occurring in the intensive care unit. Fritz, B. A. Maybrier, H. R. Avidan, M. S. British Journal of Anaesthesia 2018

NCT02032030
inhalation anesthetic agent
adult
aged
article
bispectral index
cohort analysis
controlled study
elective surgery
electroencephalogram
electroencephalography monitoring
electronic medical record
female
human
incidence
intensive care unit
major clinical study
male
postoperative delirium
prediction
priority journal
retrospective study
risk factor
sleep disordered breathing

Efficacy of perioperative dexmedetomidine on postoperative delirium: systematic review and meta-analysis with trial sequential analysis of randomised controlled trials. Duan, X. Coburn, M. Rossaint, R. Sanders, R. D. Waesberghe, J. V. Kowark, A. British Journal of Anaesthesia 2018

adult
article
bradycardia
Cochrane Library
controlled study
drug efficacy
drug therapy
female
hospital mortality
human
hypotension
incidence
intensive care unit
length of stay
male
Medline
meta analysis
postoperative delirium
postoperative period
randomized controlled trial (topic)
registration
risk assessment
risk factor
sedation
sequential analysis
surgery
surgical patient
systematic review
dexmedetomidine

Long-term sequelae of acute respiratory distress syndrome caused by severe community-acquired pneumonia: Delirium-associated cognitive impairment and post-traumatic stress disorder. Denke, C. Balzer, F. Menk, M. Szur, S. Brosinsky, G. Tafelski, S. Wernecke, K. D. Deja, M. J Int Med Res 2018

Community-acquired pneumonia
analgesia
delirium
health-related quality of life
long-term outcome
post-traumatic stress disorder

A Performing Arts Intervention Improves Cognitive Dysfunction in 50 Hospitalized Older Adults. Danila, M. I. Melnick, J. A. Mudano, A. Flood, K. Booth, K. Kirklin, K. Saag, K. G. Innov Aging 2018

Alternative and complementary medicine/care/therapy
Delirium
Quality of care

Nursing perspectives on the confusion assessment method: a qualitative focus group study. Wong, E. K. Lee, J. Y. Surendran, A. S. Nair, K. Della Maestra, N. Migliarini, M. St Onge, J. A. Patterson, C. J. Age Ageing 2018
Detection and management of hyperactive and hypoactive delirium in older patients during hospitalization: a retrospective cohort study evaluating daily practice. van Velthuijsen, E. L. Zwakhalen, S. M. G. Mulder, W. J. Verhey, F. R. J. Kempen, Gijm Int J Geriatr Psychiatry 2018

care as usual
delirium
management
prevalence
psychomotor subtypes

Glucose variability during delirium in diabetic and non-diabetic intensive care unit patients: A prospective cohort study. van Keulen, K. Knol, W. Belitser, S. V. Zaal, I. J. van der Linden, P. D. Heerdink, E. R. Egberts, T. C. G. Slooter, A. J. C. PLoS One 2018
Evaluating the use of dexmedetomidine for the reduction of delirium: An integrative review. Pavone, K. J. Cacchione, P. Z. Polomano, R. C. Winner, L. Compton, P. Heart Lung 2018

Delirium
Dexmedetomidine
Elderly
Intensive care
Mechanical ventilation
Mortality

Delirium Monitoring in Neurocritically Ill Patients: A Systematic Review. Patel, M. B. Bednarik, J. Lee, P. Shehabi, Y. Salluh, J. I. Slooter, A. J. Klein, K. E. Skrobik, Y. Morandi, A. Spronk, P. E. Naidech, A. M. Pun, B. T. Bozza, F. A. Marra, A. John, S. Pandharipande, P. P. Ely, E. W. Crit Care Med 2018
Poststroke Delirium Clinical Motor Subtypes: The PRospective Observational POLIsh Study (PROPOLIS). Pasinska, P. Kowalska, K. Klimiec, E. Wilk, A. Szyper-Maciejowska, A. Dziedzic, T. Klimkowicz-Mrowiec, A. J Neuropsychiatry Clin Neurosci 2018

Delirium
Delirium subtype
Risk Factors
Stroke and Other Cerebral Vascular Disease (Neuropsychiatric Aspects)

A systematic review of neuroimaging in delirium: predictors, correlates and consequences. Nitchingham A, Kumar V, Shenkin S, Ferguson KJ, Caplan GA International journal of geriatric psychiatry 2017

delirium
neuroimaging

The effect of dexmedetomidine on delirium and agitation in patients in intensive care: systematic review and meta-analysis with trial sequential analysis. Ng, K. T. Shubash, C. J. Chong, J. S. Anaesthesia 2018

adult
agitation
anxiety
article
bradycardia
case study
data synthesis
delirium
drug therapy
Embase
female
human
hypotension
incidence
intensive care unit
male
Medline
meta analysis
mortality
observational study
randomized controlled trial (topic)
sequential analysis
systematic review
dexmedetomidine

A Point Prevalence Study of Delirium in Italian Nursing Homes. Morichi, V. Fedecostante, M. Morandi, A. Di Santo, S. G. Mazzone, A. Mossello, E. Bo, M. Bianchetti, A. Rozzini, R. Zanetti, E. Musicco, M. Ferrari, A. Ferrara, N. Trabucchi, M. Cherubini, A. Bellelli, G. Dementia and Geriatric Cognitive Disorders 2018

neuroleptic agent
aged
article
Assessment Test for Delirium and Cognitive Impairment
controlled study
delirium
Delirium Motor Subtype Scale
dementia
education
female
functional disease
human
immobility
Italy
major clinical study
male
malnutrition
neurologic disease assessment
nursing home
prevalence
priority journal
psychopharmacotherapy
very elderly

Increased Readmission Risk and Healthcare Cost for Delirium Patients without Immediate Hospitalization in the Emergency Department. Ma, I. C. Chen, K. C. Chen, W. T. Tsai, H. C. Su, C. C. Lu, R. B. Chen, P. S. Chang, W. H. Yang, Y. K. Clin Psychopharmacol Neurosci 2018

Delirium
Health care costs
Hospital emergency service
Re-hospitalization
Risk factors

The effect of chronotherapy on delirium in critical care - a systematic review. Luther R, McLeod A Nursing in critical care 2017

Adult intensive care
practice development/innovation
psychological issues during and after intensive care
sensory imbalance

Intraoperative use of dexmedetomidine for the prevention of emergence agitation and postoperative delirium in thoracic surgery: a randomized-controlled trial. Kim, J. A. Ahn, H. J. Yang, M. Lee, S. H. Jeong, H. Seong, B. G. Canadian Journal of Anesthesia 2019

adult
antiinflammatory activity
article
clinical research
controlled study
double blind procedure
drug therapy
emergence agitation
female
human
human tissue
incidence
information service
lung lobectomy
major clinical study
male
postoperative delirium
prevention
protein blood level
randomized controlled trial
recovery room
registration
risk factor
Sedation Agitation Scale
surgery
visually impaired person
dexmedetomidine
endogenous compound
epinephrine
interleukin 10
interleukin 6
interleukin 8
noradrenalin
sevoflurane
sodium chloride

Delirium following total joint replacement surgery. Huang, J. Sprung, J. Weingarten, T. N. Bosn J Basic Med Sci 2019
Delirium management: Let's get physical? A systematic review and meta-analysis. Haley, M. N. Casey, P. Kane, R. Y. Darzins, P. Lawler, K. Australas J Ageing 2019

delirium
exercise
physical activity
physical mobility
physical therapy

Increasing Light Exposure for the Prevention of Delirium: A Systematic Review. Groves, R. L. Dimensions of Critical Care Nursing 2019

adult
aged
article
Cinahl
delirium
female
hospital patient
human
illumination
incidence
light exposure
male
Medline
neurologic disease
phototherapy
pilot study
prevention
PsycINFO
Scopus
sunlight
systematic review

Perioperative Risk Factors for Postoperative Delirium in Patients Undergoing Esophagectomy. Fuchita, M. Khan, S. H. Perkins, A. J. Gao, S. Wang, S. Kesler, K. A. Khan, B. A. Ann Thorac Surg 2019
Delirium and Alzheimer's Disease: A Proposed Model for Shared Pathophysiology. Fong, T. G. Vasunilashorn, S. M. Libermann, T. Marcantonio, E. R. Inouye, S. K. Int J Geriatr Psychiatry 2019

biomarkers
delirium
dementia

Diagnostic Performance and Utility of Quantitative EEG Analyses in Delirium: Confirmatory Results From a Large Retrospective Case-Control Study. Fleischmann, R. Tränkner, S. Bathe-Peters, R. Rönnefarth, M. Schmidt, S. Schreiber, S. J. Brandt, S. A. Clinical EEG and Neuroscience 2019

electroencephalograph
Galileo.NET
adult
aged
area under the curve
article
case control study
central nervous system infection
cerebrovascular accident
controlled study
data analysis software
delirium
dementia
diagnostic accuracy
diagnostic test accuracy study
diagnostic value
electroencephalogram
electroencephalography
electrophysiology
female
human
hypoxic ischemic encephalopathy
major clinical study
male
migraine
Parkinson disease
posterior reversible encephalopathy syndrome
predictive value
priority journal
receiver operating characteristic
reliability
retrospective study
seizure
sensitivity and specificity
split half correlation
virus encephalitis

Differences in potential biomarkers of delirium between acutely ill medical and elective cardiac surgery patients. Egberts, A. Osse, R. J. Fekkes, D. Tulen, J. H. M. van der Cammen, T. J. M. Mattace-Raso, F. U. S. Clin Interv Aging 2019

delirium
inflammation
neopterin
oxidative stress
renal function

Translation and validation of the tibetan confusion assessment method for the intensive care unit (CAM-ICU). Danzeng, Q. Z. Cui, N. Wang, H. Pan, W. J. Long, Y. Deji, Y. Z. Ze, C. Ren, Z. Chin Med J (Engl) 2019
Intra-operative Blood Transfusion Predicts Post-Operative Delirium among Older Patients Undergoing Elective Orthopedic Surgery: a Prospective Cohort Study. Chou, M. Y. Wang, Y. C. Peng, L. N. Liang, C. K. Chu, C. S. Liao, M. C. Lin, Y. T. Hsu, C. J. Chen, L. K. Int J Geriatr Psychiatry 2019

a
anemia
blood transfusion
delirium
elective orthopedic surgery

Vitamin D levels and risk of delirium: A mendelian randomization study in the UK Biobank Bowman, K. Jones, L. Pilling, L. C. Delgado, J. Kuchel, G. A. Ferrucci, L. Fortinsky, R. H. Melzer, D. Neurology 2019
Pharmacological interventions for prevention and management of delirium in intensive care patients: A systematic overview of reviews and meta-analyses. Barbateskovic, M. Krauss, S. R. Collet, M. O. Larsen, L. K. Jakobsen, J. C. Perner, A. Wetterslev, J. BMJ Open 2019

CRD42016046628
cholinesterase inhibitor
neuroleptic agent
opiate
all cause mortality
cognition
delirium
human
intensive care unit
meta analysis
quality of life
review
systematic review
unspecified side effect

Pre-operative biomarkers and imaging tests as predictors of post-operative delirium in non-cardiac surgical patients: a systematic review. Ayob, F. Lam, E. Ho, G. Chung, F. El-Beheiry, H. Wong, J. BMC Anesthesiology 2019

Post-operative delirium
Predicting post-operative delirium
Predictive biomarkers and imaging
Predictive tests
Systematic review

Training interventions to improve general hospital care for older people with cognitive impairment: systematic review. Abley, C. Dickinson, C. Andrews, Z. Prato, L. Lindley, L. Robinson, L. Br J Psychiatry 2019

Dementia
delirium
education and training
older people

Cognitive impairment and postoperative outcomes in patients undergoing primary total hip arthroplasty: A systematic review. Viramontes, O. Luan Erfe, B. M. Erfe, J. M. Brovman, E. Y. Boehme, J. Bader, A. M. Urman, R. D. J Clin Anesth 2019

Anesthesia
Cognitive impairment
Delirium
Dementia
Outcomes
Surgery

Autonomic cardiovascular control in older patients with acute infection and delirium: a pilot study of orthostatic stress responses. Neerland, B. E. Wyller, T. B. Wyller, V. B. B. BMC Geriatr 2019

Autonomic function
Delirium
Head-up tilt
Heart rate variability

The prognostic value of neurofilament levels in patients with sepsis-associated encephalopathy - A prospective, pilot observational study. Ehler, J. Petzold, A. Wittstock, M. Kolbaske, S. Gloger, M. Henschel, J. Heslegrave, A. Zetterberg, H. Lunn, M. P. Rommer, P. S. Grossmann, A. Sharshar, T. Richter, G. Noldge-Schomburg, G. Sauer, M. PLoS One 2019
A systematic review of interventions to facilitate extubation in patients difficult-to-wean due to delirium, agitation, or anxiety and a meta-analysis of the effect of dexmedetomidine. Dupuis, S. Brindamour, D. Karzon, S. Frenette, A. J. Charbonney, E. Perreault, M. M. Bellemare, P. Burry, L. Williamson, D. R. Can J Anaesth 2019
Haloperidol for the management of delirium in adult intensive care unit patients: A systematic review and meta-analysis of randomized controlled trials. Zayed, Y. Barbarawi, M. Kheiri, B. Banifadel, M. Haykal, T. Chahine, A. Rashdan, L. Aburahma, A. Bachuwa, G. Seedahmed, E. J Crit Care 2019

Critically ill patients
Delirium
Haloperidol
Icu
Meta-analysis

Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery - a sub-analysis of the RIPHeart-Study. Westphal, S. Stoppe, C. Gruenewald, M. Bein, B. Renner, J. Cremer, J. Coburn, M. Schaelte, G. Boening, A. Niemann, B. Kletzin, F. Roesner, J. Strouhal, U. Reyher, C. Laufenberg-Feldmann, R. Ferner, M. Brandes, I. F. Bauer, M. Kortgen, A. Stehr, S. N. Witt BMC Cardiovasc Disord 2019

Acute kidney injury
Atrial fibrillation
Cardiac surgery
Delirium
Genome-wide association study
Myocardial infarction
Stroke

Preoperative Anxiety as a Predictor of Delirium in Cancer Patients: A Prospective Observational Cohort Study. Wada, S. Inoguchi, H. Sadahiro, R. Matsuoka, Y. J. Uchitomi, Y. Sato, T. Shimada, K. Yoshimoto, S. Daiko, H. Shimizu, K. World J Surg 2019
Development of a Dynamic Multi-Protein Signature of Postoperative Delirium. Vasunilashorn, S. M. Ngo, L. H. Chan, N. Y. Zhou, W. Dillon, S. T. Otu, H. H. Inouye, S. K. Wyrobnik, I. Kuchel, G. A. McElhaney, J. E. Xie, Z. Alsop, D. C. Jones, R. N. Libermann, T. A. Marcantonio, E. R. J Gerontol A Biol Sci Med Sci 2019
Improved Guideline Adherence and Reduced Brain Dysfunction After a Multicenter Multifaceted Implementation of ICU Delirium Guidelines in 3,930 Patients. Trogrlic, Z. van der Jagt, M. Lingsma, H. Gommers, D. Ponssen, H. H. Schoonderbeek, J. F. J. Schreiner, F. Verbrugge, S. J. Duran, S. Bakker, J. Ista, E. Crit Care Med 2019
Trajectory of severity of postoperative delirium symptoms and its prospective association with cognitive function in patients with gastric cancer: results from a prospective observational study. Shim, E. J. Noh, H. L. Lee, K. M. Hwang, H. Son, K. L. Jung, D. Kim, W. H. Kong, S. H. Suh, Y. S. Lee, H. J. Yang, H. K. Hahm, B. J. Support Care Cancer 2019

Anesthesia
Cognitive function
Delirium
Gastrectomy
Gastric cancer

Sedation Variability Increases Incidence of Delirium in Adult Medical Intensive Care Unit Patients at a Tertiary Academic Medical Center. Ritchie, B. M. Torbic, H. DeGrado, J. R. Reardon, D. P. Am J Ther 2019
Current Pharmacotherapy Does Not Improve Severity of Hypoactive Delirium in Patients with Advanced Cancer: Pharmacological Audit Study of Safety and Efficacy in Real World (Phase-R). Okuyama, T. Yoshiuchi, K. Ogawa, A. Iwase, S. Yokomichi, N. Sakashita, A. Tagami, K. Uemura, K. Nakahara, R. Akechi, T. Oncologist 2019

Antipsychotic agents
Delirium
Neoplasms
Palliative care
Pharmacovigilance
article.

Quality of care in hospitalized cancer patients before and after implementation of a systematic prevention program for delirium: the DELTA exploratory trial. Ogawa, A. Okumura, Y. Fujisawa, D. Takei, H. Sasaki, C. Hirai, K. Kanno, Y. Higa, K. Ichida, Y. Sekimoto, A. Asanuma, C. Supportive Care in Cancer 2019

benzodiazepine derivative
neuroleptic agent
adolescent
adult
aged
article
cancer patient
child
cohort analysis
daily life activity
delirium
extubation
female
health care quality
health program
high risk population
hospital discharge
human
independence
infant
length of stay
major clinical study
male
malignant neoplasm
newborn
prescription
priority journal
retrospective study
risk factor
self concept

Relevance of peripheral cholinesterase activity on postoperative delirium in adult surgical patients (CESARO): A prospective observational cohort study. Müller, A. Olbert, M. Heymann, A. Zahn, P. K. Plaschke, K. von Dossow, V. Bitzinger, D. Barth, E. Meister, M. Kranke, P. Herrmann, C. Wernecke, K. D. Spies, C. D. European Journal of Anaesthesiology 2019

NCT01964274
adult
article
cohort analysis
controlled study
elective surgery
enzyme activity
female
hospital patient
human
major clinical study
male
middle aged
multicenter study
multivariate logistic regression analysis
nursing
observational study
perioperative period
postoperative delirium
postoperative period
preoperative evaluation
prospective study
protein function
regulatory mechanism
risk assessment
surgery
surgical patient
acetylcholinesterase
cholinesterase
endogenous compound
hemoglobin

Predicting postoperative delirium and postoperative cognitive decline with combined intraoperative electroencephalogram monitoring and cerebral near-infrared spectroscopy in patients undergoing cardiac interventions. Momeni, M. Meyer, S. Docquier, M. A. Lemaire, G. Kahn, D. Khalifa, C. Rosal Martins, M. Van Dyck, M. Jacquet, L. M. Peeters, A. Watremez, C. J Clin Monit Comput 2019

Burst suppression
Cerebral oximetry
Depth-of-anesthesia monitor
Postoperative cognitive decline
Postoperative delirium

Early Postoperative Actigraphy Poorly Predicts Hypoactive Delirium. Maybrier, H. R. King, C. R. Crawford, A. E. Mickle, A. M. Emmert, D. A. Wildes, T. S. Avidan, M. S. Palanca, B. J. A. J Clin Sleep Med 2019

actigraphy
anesthesia
arousal
postoperative delirium
sleep
surgery

Subsyndromal delirium is associated with poor functional outcome after ischemic stroke. Klimiec, E. Lis, A. Pera, J. Slowik, A. Dziedzic, T. Eur J Neurol 2019

confusion
delirium
outcome
stroke
subsyndromal delirium

Pharmacological Management of Delirium in the Intensive Care Unit: A Randomized Pragmatic Clinical Trial. Khan, B. A. Perkins, A. J. Campbell, N. L. Gao, S. Farber, M. O. Wang, S. Khan, S. H. Zarzaur, B. L. Boustani, M. A. J Am Geriatr Soc 2019

benzodiazepine
delirium
haloperidol
randomized trial

Use of medicines that may precipitate delirium prior to hospitalisation in older Australians with delirium: An observational study. Kassie, G. M. Kalisch Ellett, L. M. Nguyen, T. A. Roughead, E. E. Australas J Ageing 2019

delirium
drug utilization
inappropriate prescribing
medication review
older patients

Comprehensive risk factor evaluation of postoperative delirium following major surgery: clinical data warehouse analysis. Kang, S. Y. Seo, S. W. Kim, J. Y. Neurol Sci 2019

Clinical data warehouse
Delirium
Operation
Parkinsonism
Risk factor
Type of surgery

Lower risk of postoperative delirium using laparoscopic approach for major abdominal surgery. Ito, K. Suka, Y. Nagai, M. Kawasaki, K. Yamamoto, M. Koike, D. Nomura, Y. Tanaka, N. Kawaguchi, Y. Surg Endosc 2019

Laparoscopic approach
Major abdominal surgery
Open approach
Postoperative delirium

Delirium is associated with frequency band specific dysconnectivity in intrinsic connectivity networks: preliminary evidence from a large retrospective pilot case-control study. Fleischmann, R. Traenkner, S. Kraft, A. Schmidt, S. Schreiber, S. J. Brandt, S. A. Pilot Feasibility Stud 2019

Biomarker
Delirium
Oscillatory activity
Source analysis
electroencephalography
accordance with the ethical standards of the institutional research committee and
with the 1964 Helsinki declaration and its later amendments or comparable ethical
standards. As a retrospective study in Germany, a separate approval is waived.Not
applicable.The authors declare that they have no competing interests.Springer
Nature remains neutral with regard to jurisdictional claims in published maps and
institutional affiliations.

Risk Factors Associated With Postoperative Delirium in Patients Undergoing Head and Neck Free Flap Reconstruction. Densky, J. Eskander, A. Kang, S. Chan, J. Tweel, B. Sitapara, J. Ozer, E. Agrawal, A. Carrau, R. Rocco, J. Teknos, T. N. Old, M. JAMA Otolaryngol Head Neck Surg 2019
Deprescribing in the Pharmacologic Management of Delirium: A Randomized Trial in the Intensive Care Unit. Campbell, N. L. Perkins, A. J. Khan, B. A. Gao, S. Farber, M. O. Khan, S. Wang, S. Boustani, M. A. J Am Geriatr Soc 2019

anticholinergic
benzodiazepine
delirium
deprescribing

Reliability of mobility measures in older medical patients with cognitive impairment. Braun, T. Thiel, C. Schulz, R. J. Gruneberg, C. BMC Geriatr 2019

Cognitive impairment
Dementia
Limits of agreement
Measurement error
Minimal detectable change
Mobility limitation
Older people
Outcome measure
Reliability

Effectiveness of Melatonin for the Prevention of Intensive Care Unit Delirium. Baumgartner, L. Lam, K. Lai, J. Barnett, M. Thompson, A. Gross, K. Morris, A. Pharmacotherapy 2019

Delirium
intensive-care unit
melatonin
sleep

Validation of the Prediction of Delirium for Intensive Care model to predict subsyndromal delirium. Azuma, K. Mishima, S. Shimoyama, K. Ishii, Y. Ueda, Y. Sakurai, M. Morinaga, K. Fujikawa, T. Oda, J. Acute Med Surg 2019

Critical care
delirium
intensive care unit
psychiatry
sleep

Association Between Postoperative Delirium and Long-term Cognitive Function After Major Nonemergent Surgery. Austin, C. A. O'Gorman, T. Stern, E. Emmett, D. Sturmer, T. Carson, S. Busby-Whitehead, J. JAMA Surg 2019
'I hope you get normal again': an explorative study on how delirious octogenarian patients experience their interactions with healthcare professionals and relatives after aortic valve therapy. Instenes, I. Fridlund, B. Amofah, H. A. Ranhoff, A. H. Eide, L. S. Norekval, T. M. Eur J Cardiovasc Nurs 2018

Delirium
octogenarian patients
qualitative research
surgical aortic valve replacement
transcatheter aortic valve replacement

Establishing a successful perioperative geriatric service in an Australian acute surgical unit. Styan, L. Murphy, S. Fleury, A. McGowan, B. Wullschleger, M. ANZ Journal of Surgery 2018

aged
article
cohort analysis
complication
controlled study
delirium
female
general surgery
hospital mortality
human
length of stay
male
medical record review
morbidity
peroperative complication
retrospective study
surgery

Delirium and Antipsychotic Medications at Hospital Intake: Screening to Decrease Likelihood of Aggression in Inpatient Settings Among Unknown Patients With Dementia. Wharton, T. Paulson, D. Burcher, K. Lesch, H. Am J Alzheimers Dis Other Demen 2018

behavior
delirium
medication
screening

Preoperative assessment of frailty predicts age-related events after hepatic resection: a prospective multicenter study. Tanaka, S. Ueno, M. Iida, H. Kaibori, M. Nomi, T. Hirokawa, F. Ikoma, H. Nakai, T. Eguchi, H. Kubo, S. J Hepatobiliary Pancreat Sci 2018

Age Factors
Aged
Aged, 80 and over
Comorbidity
Female
Frailty/*diagnosis
*Geriatric Assessment
Hepatectomy/*adverse effects
Humans
Liver Diseases/surgery
Liver Neoplasms/*surgery
Male
Preoperative Period
Prospective Studies
Risk Factors
Delirium
Dependency
Kihon Checklist
Phenotypic frail index
Transfer

Efficacy and Tolerability of Atypical Antipsychotics in the Treatment of Delirium: A Systematic Review of the Literature. Rivière, J. van der Mast, R. C. Vandenberghe, J. Van Den Eede, F. Psychosomatics 2018

aged
article
comparative study
controlled study
delirium
drug combination
drug therapy
extrapyramidal symptom
female
human
incidence
male
Medline
meta analysis
open study
randomized controlled trial (topic)
sedation
systematic review
amisulpride
aripiprazole
asenapine
clozapine
haloperidol
iloperidone
lurasidone
olanzapine
paliperidone
perospirone
placebo
quetiapine
risperidone
sertindole
ziprasidone
zotepine

Outcomes of Prehospital Chemical Sedation With Ketamine Versus Haloperidol and Benzodiazepine or Physical Restraint Only. O'Connor, L. Rebesco, M. Robinson, C. Gross, K. Castellana, A. O'Connor, M. J. Restuccia, M. Preshosp Emerg Care 2018

agitated delirium
ketamine
restraint
sedation

Just another piece of paperwork": perceptions of clinicians on delirium screening following hip fracture repair elicited in focus groups. Oberai, T. Killington, M. Laver, K. Crotty, M. Jaarsma, R. Int Psychogeriatr 2018

aging
cognitive impairment
delirium
qualitative research

Altered mental status predicts mortality in cardiogenic shock – results from the CardShock study. Kataja, A. Tarvasmäki, T. Lassus, J. Køber, L. Sionis, A. Spinar, J. Parissis, J. Carubelli, V. Cardoso, J. Banaszewski, M. Marino, R. Nieminen, M. S. Mebazaa, A. Harjola, V. P. European Heart Journal: Acute Cardiovascular Care 2018

NCT01374867
adult
aged
arterial pH
article
cardiogenic shock
cardiovascular mortality
clinical assessment
female
heart left ventricle ejection fraction
human
lactate blood level
major clinical study
male
mental health
multicenter study
observational study
prevalence
priority journal
prospective study
systolic blood pressure

Nurses' and physicians' approaches to delirium management in the intensive care unit: A focus group investigation. Collet, M. O. Thomsen, T. Egerod, I. Aust Crit Care 2018

Delirium
Focus groups
Hermeneutics
Intensive care unit
Nursing care
Pharmacological action
Qualitative research

Low Plasma Cholinesterase Activity is Associated With Postoperative Delirium After Noncardiac Surgery in Elderly Patients: A Prospective Observational Study. Zhao, B. Ni, Y. Tian, X. Psychosomatics 2018

aged
alcohol consumption
APACHE
article
cholinesterase blood level
cohort analysis
comorbidity
confounding variable
controlled study
enzyme activity
female
Han Chinese
human
human tissue
incidence
major clinical study
male
multivariate logistic regression analysis
observational study
postoperative delirium
prospective study
risk factor
surgery
surgical intensive care unit
acetylcholinesterase
biological marker
cholinesterase
endogenous compound

Propofol compared with sevoflurane general anaesthesia is associated with decreased delayed neurocognitive recovery in older adults. Zhang, Y. Shan, G. J. Zhang, Y. X. Cao, S. J. Zhu, S. N. Li, H. J. Ma, D. Wang, D. X. British Journal of Anaesthesia 2018

ChiCTR-IPR-15006209
NCT02662257
propofol
sevoflurane
aged
anesthetic recovery
APACHE
article
bispectral index
bradycardia
bronchospasm
cancer surgery
cognition
comparative study
controlled study
delayed neurocognitive recovery
electrocardiogram
emergence agitation
end tidal carbon dioxide tension
female
general anesthesia
heart ventricle extrasystole
human
hypertension
hypotension
intraoperative monitoring
major clinical study
male
multicenter study
neuropsychological test
oxygen saturation
patient safety
perioperative period
postoperative cognitive dysfunction
postoperative nausea and vomiting
priority journal
randomized controlled trial
tachycardia
very elderly

Effect of dexmedetomidine on postoperative delirium in elderly patients undergoing hip fracture surgery. Xie, S. Xie, M. Pak J Pharm Sci 2018
Development and Validation of an Electronic Health Record-Based Machine Learning Model to Estimate Delirium Risk in Newly Hospitalized Patients Without Known Cognitive Impairment. Wong, A. Young, A. T. Liang, A. S. Gonzales, R. Douglas, V. C. Hadley, D. JAMA Netw Open 2018
Sedative drugs used for mechanically ventilated patients in intensive care units: a systematic review and network meta-analysis. Wang, H. Wang, C. Wang, Y. Tong, H. Feng, Y. Li, M. Jia, L. Yu, K. Curr Med Res Opin 2018

Sedative drugs
intensive care units
mechanical ventilation
mortality
network meta-analysis
systematic review

Prediction of length of hospital stay and mortality in patients with delirium: A prospective cohort analysis of 200 ICU patients. Tian, J. Chen, X. Liu, D. Journal of Biological Regulators and Homeostatic Agents 2018

adult
age
aged
article
cohort analysis
critically ill patient
disease association
female
hospital mortality
human
intensive care psychosis
length of stay
major clinical study
male
observational study
prediction
probability
prospective study

Ramelteon is Not Associated With Improved Outcomes Among Critically Ill Delirious Patients: A Single-Center Retrospective Cohort Study. Thom, R. Bui, M. Rosner, B. Teslyar, P. Levy-Carrick, N. Wolfe, D. Klompas, M. Psychosomatics 2018

Delirium
Melatonin
Mortality
Ramelteon
Ventilation

A daily multidisciplinary assessment of older adults undergoing elective colorectal cancer surgery is associated with reduced delirium and geriatric syndromes. Tarazona-Santabalbina, F. J. Llabata-Broseta, J. Belenguer-Varea, A. Alvarez-Martinez, D. Cuesta-Peredo, D. Avellana-Zaragoza, J. A. J Geriatr Oncol 2018

Colorectal surgery
Delirium
Frail
Geriatric assessment
Older patients

Preventive Effect of Suvorexant for Postoperative Delirium after Coronary Artery Bypass Grafting. Tamura, K. Maruyama, T. Sakurai, S. Ann Thorac Cardiovasc Surg 2018

Suvorexant
coronary artery bypass grafting
orexin receptor antagonist
postoperative delirium

Aproach to the risk of delirium in an orthogeriatric unit. Sopena Bert, E. Qanneta, R. Valenti Moreno, V. San Jose Laporte, A. Med Clin 2018

Delirium
Fractura de cadera
Hip fracture
Orthogeriatrics
Ortogeriatria

A systematic review of the use of music interventions to improve outcomes for patients undergoing hip or knee surgery. Sibanda, A. Carnes, D. Visentin, D. Cleary, M. J Adv Nurs 2018

anxiety
hip surgery
knee surgery
literature review
music interventions
nursing
pain
postoperative delirium

Use of "Months of the Year Backwards" (MOTYB) as a Screening Tool for Delirium in Palliative Care Patients in the Acute Hospital Setting. Ryan, S. Hayes, D. Creedon, B. Ir Med J 2018
Impact of psychotic symptoms on clinical outcomes in delirium. Paik, S. H. Ahn, J. S. Min, S. Park, K. C. Kim, M. H. PLoS ONE 2018

neuroleptic agent
age distribution
aged
article
clinical outcome
comorbidity
controlled study
delirium
Delirium Rating Scale revised 98
delusion
disease classification
disease course
disease severity
female
hospital mortality
human
major clinical study
male
medical record review
patient assessment
perception disorder
psychosis
retrospective study
scoring system
sex difference
thought disorder

Preoperative age and prognostic nutritional index are useful factors for evaluating postoperative delirium among patients with adult spinal deformity. Oe, S. Togawa, D. Yamato, Y. Hasegawa, T. Yoshida, G. Kobayashi, S. Yasuda, T. Banno, T. Arima, H. Mihara, Y. Ushirozako, H. Yamada, T. Matsuyama, Y. Spine 2018
Decreased Risk of Delirium With Use of Regional Analgesia in Geriatric Trauma Patients With Multiple Rib Fractures. O'Connell, K. M. Quistberg, D. A. Tessler, R. Robinson, B. R. H. Cuschieri, J. Maier, R. V. Rivara, F. P. Vavilala, M. S. Bhalla, P. I. Arbabi, S. Ann Surg 2018

OBJECTIVE: The aim of this study was to examine the risk of delirium in geriatric trauma patients with rib fractures treated with systemic opioids compared with those treated with regional analgesia (RA). SUMMARY OF BACKGROUND DATA: Delirium is a modifiable complication associated with increased morbidity and mortality. RA may reduce the need for opioid medications, which are associated with delirium in older adults. METHODS: Cohort study of patients >/=65 years admitted to a regional trauma center from 2011 to 2016. Inclusion factors were >/= 3 rib fractures, blunt trauma mechanism, and admission to intensive care unit (ICU). Exclusion criteria included head AIS >/=3, spine AIS >/=3, dementia, and death within 24 hours. The primary outcome was delirium positive ICU days, defined using the CAM-ICU assessment. Delirium incident rate ratios (IRRs) and 95% confidence intervals (95% CIs) were estimated using generalized linear mixed models with Poisson distribution and robust standard errors. RESULTS: Of the 144 patients included in the study, 27 (19%) received Acute Pain Service consultation and RA and 117 (81%) received opioid-based systemic analgesia. Patients with RA had more severe chest injury than those without. The risk of delirium decreased by 24% per day per patient with use of RA (IRR 0.76, 95% CI 0.61 to 0.96). Individual opioid use, as measured in daily morphine equivalents (MEDs), was significantly reduced after initiation of RA (mean difference -7.62, 95% CI -14.4 to -0.81). CONCLUSION: Although use of RA techniques in geriatric trauma patients with multiple rib fractures was associated with higher MED, opioid use decreased after RA initiation and Acute Pain Service consultation, and the risk of delirium was lower.

Hypotension and a positive fluid balance are associated with delirium in patients with shock. Nguyen, D. N. Huyghens, L. Parra, J. Schiettecatte, J. Smitz, J. Vincent, J. L. PLoS One 2018
End-Tidal Hypocapnia Under Anesthesia Predicts Postoperative Delirium. Mutch, W. A. C. El-Gabalawy, R. Girling, L. Kilborn, K. Jacobsohn, E. Front Neurol 2018

*anesthetic agent
*carbon dioxide
*cognition
*hypercapnia
*hypocapnia
*normocapnia
*postoperative complications
*postoperative delirium

Risk Factors for Delirium after Spine Surgery: An Age-Matched Analysis. Morino, T. Hino, M. Yamaoka, S. Misaki, H. Ogata, T. Imai, H. Miura, H. Asian Spine J 2018

Delirium
Hemorrhage
Multivariate analysis
Risk factors
Spine

Outcomes of Patients With Delirium in Long-Term Care Facilities: A Prospective Cohort Study. Moon, K. J. Park, H. J Gerontol Nurs 2018

Aged
Aged, 80 and over
Cohort Studies
Delirium/*mortality/*nursing
Dementia/*mortality/*nursing
Female
Hospitalization/statistics & numerical data
Humans
Incidence
Long-Term Care/*methods/*statistics & numerical data
Male
Middle Aged
Patient Discharge/statistics & numerical data
Prospective Studies
Republic of Korea
Skilled Nursing Facilities/*statistics & numerical data
Treatment Outcome

Intravenous versus inhalational maintenance of anaesthesia for postoperative cognitive outcomes in elderly people undergoing non-cardiac surgery. Miller, D. Lewis, S. R. Pritchard, M. W. Schofield-Robinson, O. J. Shelton, C. L. Alderson, P. Smith, A. F. Cochrane Database of Systematic Reviews 2018

Aged
Anesthesia, Inhalation
Anesthesia, Intravenous
Anesthetics, Inhalation
Anesthetics, Intravenous/*adverse effects
Cognition/*drug effects
Cognition Disorders/chemically induced
Delirium/chemically induced
Desflurane
Humans
Hypotension/chemically induced
Isoflurane/adverse effects/analogs & derivatives
Methyl Ethers/adverse effects
Middle Aged
Postoperative Complications/chemically induced/mortality
Propofol/*adverse effects
Randomized Controlled Trials as Topic
Sevoflurane
*Surgical Procedures, Operative