Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Low-dose Nocturnal Dexmedetomidine Prevents ICU Delirium: A Randomized, Placebo-controlled Trial.
Authors
Skrobik, Y. Duprey, M. S. Hill, N. S. Devlin, J. W.
Year
2018
Journal
Am J Respir Crit Care Med
Abstract

RATIONALE: Dexmedetomidine is associated with less delirium than benzodiazepines, and better sleep architecture than either benzodiazepines or propofol; its effect on delirium and sleep when administered at night to patients requiring sedation remains unclear. OBJECTIVES: To determine if nocturnal dexmedetomidine prevents delirium and improves sleep in critically ill adults. METHODS: This two-center, double-blind, placebo-controlled trial randomized 100 delirium-free critically ill adults receiving sedatives to receive nocturnal (21:30 to 6:15h) intravenous dexmedetomidine (0.2 mcg/kg/hr, titrated by 0.1 mcg/kg/hr every 15 minutes until a goal RASS = -1 or maximum rate of 0.7 mcg/kg/hr was reached) or placebo until ICU discharge. During study infusions, all sedatives were halved; opioids were unchanged. Delirium was assessed using the Intensive Care Delirium Screening Checklist every 12 hours throughout the ICU admission. Sleep was evaluated each morning by the Leeds Sleep Evaluation Questionnaire (LSEQ). MEASUREMENTS AND MAIN RESULTS: Nocturnal dexmedetomidine (versus placebo) was associated with a greater proportion of patients who remained delirium-free during the ICU stay [dexmedetomidine [40 (80%) of 50 patients] vs. placebo [27 (54%) of 50 patients] (RR = 0.44, 95% CI, 0.23 to 0.82, p=0.006). The average LSEQ score was similar [MD 0.02; 95% CI, 0.42 to 1.92] between the 34 dexmedetomidine (average 7 assessments/patient) and 30 placebo (6/patient) group patients able to provide >/= 1 assessment. Incidence of hypotension, bradycardia or both did not differ significantly between groups. CONCLUSIONS: Nocturnal administration of low-dose dexmedetomidine in critically ill adults reduces the incidence of delirium during the ICU stay; patient-reported sleep quality appears unchanged. Clinical trial registration available at www.clinicaltrials.gov, ID NCT01791296.

PMID

29498534

Keywords

delirium, sleep, intensive care, dexmedetomidine, randomized controlled trial

Page(s)
Issue

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Total Records Found: 6740, showing 100 per page
TitleAuthorsJournalYearKeywords
The Risk Factors of Postoperative Delirium after Total Knee Arthroplasty. Wang, L. Seok, S. Kim, S. Kim, K. Lee, S. Lee, K. J Knee Surg 2017
Risk factors for the incidence of delirium in cerebrovascular patients in a Neurosurgery Intensive Care Unit: A prospective study. Wang, J. Ji, Y. Wang, N. Chen, W. Bao, Y. Qin, Q. Xiao, Q. Li, S. J Clin Nurs 2017

delirium (mental health nursing)
intensive care
neurosurgery
outcomes
risk factor

Clock-Drawing Test as a Bedside Assessment of Post-operative Delirium Risk in Elderly Patients with Accidental Hip Fracture. Vasilian, C. C. Tamasan, S. C. Lungeanu, D. Poenaru, D. V. World J Surg 2017
A prospective observational study to investigate utility of the Delirium Observational Screening Scale (DOSS) to detect delirium in care home residents. Teale, E. A. Munyombwe, T. Schuurmans, M. Siddiqi, N. Young, J. Age & Ageing 2017

Delirium Observation Screening Scale
care home
delirium
diagnostic test accuracy
older people
screening

Randomized phase II study of TJ-54 (Yokukansan) for postoperative delirium in gastrointestinal and lung malignancy patients. Sugano, N. Aoyama, T. Sato, T. Kamiya, M. Amano, S. Yamamoto, N. Nagashima, T. Ishikawa, Y. Masudo, K. Taguri, M. Yamanaka, T. Yamamoto, Y. Matsukawa, H. Shiraisi, R. Oshima, T. Yukawa, N. Rino, Y. Masuda, M. Mol Clin Oncol 2017

Yokukansan
gastrointestinal cancer
lung cancer
postoperative delirium

Postoperative delirium in elderly patients is associated with subsequent cognitive impairment. Sprung, J. Roberts, R. O. Weingarten, T. N. Nunes Cavalcante, A. Knopman, D. S. Petersen, R. C. Hanson, A. C. Schroeder, D. R. Warner, D. O. Br J Anaesth 2017

aged, humans
delirium
dementia
female
anaesthesia
general
male
mild cognitive impairment
surgery

Delirium Following Transcatheter Aortic Valve Replacement: National Inpatient Sample Analysis. Soundhar, A. Udesh, R. Mehta, A. Schindler, J. Jeevanantham, V. Gleason, T. Thirumala, P. D. Journal of Cardiothoracic and Vascular Anesthesia 2017

carotid artery obstruction
confidence interval
congenital malformation
data base
electrolyte disturbance
female
hospital mortality
hospital patient
human
ICD-9-CM
major clinical study
male
morbidity
neurologic disease
odds ratio
postoperative delirium
risk factor
screening
statistical analysis
surgery
transcatheter aortic valve implantation
weight reduction
electrolyte

The Effects of Delirium Prevention Guidelines on Elderly Stroke Patients Song, J. Lee, M. Jung, D. Clin Nurs Res 2017

delirium
delirium prevention
post-stroke delirium

Postoperative Delirium in Elderly Patients Undergoing Major Spinal Surgery: Role of Cerebral Oximetry. Soh S, Shim JK, Song JW, Kim KN, Noh HY, Kwak YL Journal of neurosurgical anesthesiology 2016
Age and gender-related peculiarities of patients with delirium in the cardiac intensive care unit. Serpytis, P. Navickas, P. Navickas, A. Serpytis, R. Navickas, G. Glaveckaite, S. Kardiol Pol 2017

Iccu
age
cardiac care
delirium
gender

Outcomes of subsyndromal delirium in ICU: a systematic review and meta-analysis. Serafim, R. B. Soares, M. Bozza, F. A. Lapa, E. Silva J. R. Dal-Pizzol, F. Paulino, M. C. Povoa, P. Salluh, J. I. F. Crit Care 2017

Critically ill
Delirium
Icu
Subsyndromal delirium

Haloperidol versus placebo for delirium prevention in acutely hospitalised older at risk patients: a multi-centre double-blind randomised controlled clinical trial. Schrijver, E. J. M. de Vries, O. J. van de Ven, P. M. Bet, P. M. Kamper, A. M. Diepeveen, S. H. A. van Marum, R. J. van Strien, A. M. Anten, S. Lagaay, A. M. Boelaarts, L. Bloemers, F. W. Kramer, M. H. H. Nanayakkara, P. W. B. Age & Ageing 2017

aged 80 and over
delirium
haloperidol
older people
prevention

The impact of delirium on outcomes in acute, non-intubated cardiac patients. Sato K, Kubota K, Oda H, Taniguchi T European heart journal. Acute cardiovascular care 2015

Aging
cardiovascular disease
cerebrovascular disorder
delirium
mortality

Epidemiology and outcomes of people with dementia, delirium, and unspecified cognitive impairment in the general hospital: prospective cohort study of 10,014 admissions. Reynish, Emma L. Hapca, Simona M. De Souza, Nicosha Cvoro, Vera Donnan, Peter T. Guthrie, Bruce BMC Medicine 2017
Alzheimer's-related cortical atrophy is associated with postoperative delirium severity in persons without dementia. Racine, A. M. Fong, T. G. Travison, T. G. Jones, R. N. Gou, Y. Vasunilashorn, S. M. Marcantonio, E. R. Alsop, D. C. Inouye, S. K. Dickerson, B. C. Neurobiol Aging 2017

Alzheimer’s disease
Atrophy
Biomarker
Cortical thickness
Delirium
Delirium severity
Neurodegeneration
Preclinical Alzheimer’s disease

Delayed Recall and Working Memory MMSE Domains Predict Delirium following Cardiac Surgery. Price, C. C. Garvan, C. Hizel, L. Lopez, M. G. Billings, F. T. J Alzheimers Dis 2017

Alzheimer’s disease
cardiovascular surgical procedures
cognition
cognitive dysfunction
confusion
dementia
screening
thoracic surgery

The detection, diagnosis, and impact of cognitive impairment among inpatients aged 65 years and over in an Irish general hospital - a prospective observational study. Power, C. Duffy, R. Bates, H. Healy, M. Gleeson, P. Lawlor, B. A. Greene, E. Int Psychogeriatr 2017

cognitive impairment
delirium
dementia
elderly

Incidence and predictors of postoperative delirium after cytoreduction surgery-hyperthermic intraperitoneal chemotherapy. Plas, M. Hemmer, P. H. J. Been, L. B. van Ginkel, R. J. de Bock, G. H. van Leeuwen, B. L. J Surg Oncol 2017

C-reactive protein
cognition disorders
cytoreduction surgical procedures
delirium
neoplasm
postoperative complications

Role of Ramelteon in Reduction of As-Needed Antipsychotics in Elderly Patients with Delirium in a General Hospital Setting. Pinkhasov, A. James, S. A. Fazzari, M. Singh, D. Lam, S. Clin Drug Investig 2017
Delirium after fast-track hip and knee arthroplasty - a cohort study of 6331 elderly patients. Petersen, P. B. Jorgensen, C. C. Kehlet, H. Acta Anaesthesiol Scand 2017
Delirium Risk of Dexmedetomidine and Midazolam in Patients Treated with Postoperative Mechanical Ventilation: a Meta-analysis. Peng, W. Shimin, S. Hongli, W. Yanli, Z. Ying, Z. Open Med 2017

Delirium
Dexmedetomidine
Meta-analysis
Midazolam
Postoperative mechanical ventilation

Humanizing the treatment of hyperactive delirium in the last days of life. Pandharipande, P. P. Ely, E. W. JAMA 2017

haloperidol
lorazepam
neuroleptic agent
placebo
agitation
controlled study
delirium
disease severity
distress syndrome
editorial
human
human needs
hyperactive delirium
hyperactivity
interpersonal communication
Karnofsky Performance Status
major clinical study
Memorial Delirium Assessment Scale
mental disease assessment
palliative therapy
patient care
priority journal
randomized controlled trial
restlessness
Richmond Agitation Sedation Scale

Evaluation of early administration of simvastatin in the prevention and treatment of delirium in critically ill patients undergoing mechanical ventilation (MoDUS): a randomised, double-blind, placebo-controlled trial. Page, V. J. Casarin, A. Ely, E. W. Zhao, X. B. McDowell, C. Murphy, L. McAuley, D. F. Lancet Respir Med 2017
The effect of nonpharmacological training on delirium identification and intervention strategies of intensive care nurses. Ozturk Birge, A. Tel Aydin, H. Intensive Crit Care Nurs 2017

Adult
Chi-Square Distribution
Clinical Competence/*standards
Critical Care Nursing/*methods/standards/statistics & numerical data
Delirium/*diagnosis
Female
Hospitals, University/organization & administration/statistics & numerical data
Humans
Intensive Care Units/organization & administration/standards/statistics &
numerical data
Logistic Models
Male
Risk Factors
Teaching/standards/statistics & numerical data
Turkey
Delirium
Intensive care unit
Nonpharmacological intervention
Nursing
Risk factor

Validation of the 6-Item Cognitive Impairment Test and the 4AT test for combined delirium and dementia screening in older Emergency Department attendees. O'Sullivan, D. Brady, N. Manning, E. O'Shea, E. O'Grady, S. O. ' Regan N Timmons, S. Age & Ageing 2017

delirium
dementia
emergency department
older people
screening

Risk factors for delirium after cardiac surgery: a historical cohort study outlining the influence of cardiopulmonary bypass. O'Neal, J. B. Billings, F. T. th Liu, X. Shotwell, M. S. Liang, Y. Shah, A. S. Ehrenfeld, J. M. Wanderer, J. P. Shaw, A. D. Can J Anaesth 2017
A systematic review and meta-analysis of factors for delirium in vascular surgical patients. Oldroyd, C. Scholz, A. F. M. Hinchliffe, R. J. McCarthy, K. Hewitt, J. Quinn, T. J. J Vasc Surg 2017

Delirium/diagnosis/*etiology/psychology/therapy
Humans
Multivariate Analysis
Odds Ratio
Risk Assessment
Risk Factors
Treatment Outcome
Vascular Surgical Procedures/*adverse effects

Detection and Management of Preexisting Cognitive Impairment in the Critical Care Unit. Oldham, M. A. Piddoubny, W. Peterson, R. Lee, H. B. Crit Care Clin 2017

Behavioral and psychological symptoms in dementia
Cognitive impairment
Delirium
Dementia
Neuropsychiatric symptoms

Delirium in older persons: Advances in diagnosis and treatment. Oh, E. S. Fong, T. G. Hshieh, T. T. Inouye, S. K. JAMA 2017

biological marker
dexmedetomidine
diazepam
diphenhydramine
donepezil
gabapentin
haloperidol
melatonin
methylprednisolone
morphine sulfate
ondansetron
pregabalin
quetiapine
ramelteon
risperidone
sevoflurane
sugammadex
aged
brain depth stimulation
clinical feature
Confusion Assessment Method
delirium
diagnostic test accuracy study
disease severity
electroencephalography
human
mental disease assessment
meta analysis
phototherapy
priority journal
review
risk assessment
risk factor
sensitivity and specificity
sleep
systematic review
Three Minute Diagnostic Assessment

Prevalence for delirium in stroke patients: A prospective controlled study. Nydahl, P. Bartoszek, G. Binder, A. Paschen, L. Margraf, N. G. Witt, K. Ewers, A. Brain Behav 2017

Confusion Assessment Method
delirium
rehabilitation
stroke unit

Perioperative hemodynamics and risk for delirium and new onset dementia in hip fracture patients; A prospective follow-up study. Neerland, B. E. Krogseth, M. Juliebo, V. Hylen Ranhoff, A. Engedal, K. Frihagen, F. Raeder, J. Bruun Wyller, T. Watne, L. O. PloS One 2017
Identification of patients with cancer with a high risk to develop delirium. Neefjes, E. C. W. van der Vorst, Mjdl Verdegaal, Batt Beekman, A. T. F. Berkhof, J. Verheul, H. M. W. Cancer Med 2017

Cancer
delirium
epidemiology
medical oncology
prevention
risk factors

Perioperative prediction of agitated (hyperactive) delirium after cardiac surgery in adults - The development of a practical scorecard. Mufti, H. N. Hirsch, G. M. J Crit Care 2017

Cabg
Cardiac surgery
Delirium
Scorecard
Valve surgery

Development and validation of an automated delirium risk assessment system (Auto-DelRAS) implemented in the electronic health record system. Moon, K. J. Jin, Y. Jin, T. Lee, S. M. Int J Nurs Stud 2017

Auto-DelRAS
Automated delirium risk assessment
Delirium
Electronic health record
Intensive care unit

Efficacy of Ramelteon for delirium after lung cancer surgery. Miyata R, Omasa M, Fujimoto R, Ishikawa H, Aoki M Interactive cardiovascular and thoracic surgery 2016

indene derivative
ramelteon
adverse effects
aged
checklist
delirium
female
human
incidence
lung tumor
lung resection
male
postoperative complication
psychology
retrospective study
very elderly

Risk Factors for Postoperative Delirium in Abdominal Surgery: A Proposal of a Postoperative Delirium Risk Score in Abdominal Surgery. Miyagawa, Y. Yokoyama, Y. Fukuzawa, S. Fukata, S. Ando, M. Kawamura, T. Yamada, K. Nagino, M. Digestive Surgery 2017

serum albumin
sodium
abdomen
abdominal surgery
adult
adverse effects
age
aged
blood
delirium
female
human
hypertension
intensive care
male
middle aged
postoperative complication
procedures
prospective study
risk assessment
risk factor
surgery
very elderly
young adult

Long-term cognitive impairment and delirium in intensive care: A prospective cohort study. Mitchell, M. L. Shum, D. H. K. Mihala, G. Murfield, J. E. Aitken, L. M. Aust Crit Care 2017

Cognition
Critical illness
Delirium
Intensive care units
Long-term effects
Patient outcome assessment

Prevalence of delirium in advanced cancer patients in home care and hospice and outcomes after 1 week of palliative care. Mercadante, S. Masedu, F. Balzani, I. De Giovanni, D. Montanari, L. Pittureri, C. Berte, R. Russo, D. Ursini, L. Marinangeli, F. Aielli, F. Support Care Cancer 2017

Advanced cancer
Delirium
Home care
Hospice care
Palliative care

Characterizing and predicting rates of delirium across general hospital settings. McCoy, Thomas H. Hart, Kamber L. Perlis, Roy H. General Hospital Psychiatry 2017

Delirium
Acute confusional state
Electronic health record
Epidemiology
2017
Hospitals
Medical Records

Environmental and Clinical Risk Factors for Delirium in a Neurosurgical Center: A Prospective Study. Matano, F. Mizunari, T. Yamada, K. Kobayashi, S. Murai, Y. Morita, A. World Neurosurg 2017

Delirium
Environmental
Neurosurgical center
Risk factor
White matter signal abnormalities

Genetic and environmental factors associated with delirium severity in older adults with dementia Massimo, Lauren Munoz, Elizabeth Hill, Nikki Mogle, Jacqueline Mulhall, Paula McMillan, Corey T. Clare, Linda Vandenbergh, David Fick, Donna Kolanowski, Ann International Journal of Geriatric Psychiatry 2017

delirium
dementia
APOE
cognitive reserve
2017
Genotypes
Severity (Disorders)

Delirium in Hospitalized Older Adults. Marcantonio, E. R. N Engl J Med 2017

Aged
Delirium/chemically induced/diagnosis/etiology/*therapy
*Hospitalization
Humans
Male
Postoperative Complications/chemically induced/diagnosis/*therapy
Practice Guidelines as Topic
Risk Factors

A post cardiac surgery intervention to manage delirium involving families: a randomized pilot study. Mailhot, T. Cossette, S. Cote, J. Bourbonnais, A. Cote, M. C. Lamarche, Y. Denault, A. Nurs Crit Care 2017

Cardiac surgery
Delirium
Family caregiver
Non-pharmacological interventions
Self-efficacy

The influence of analgesic-based sedation protocols on delirium and outcomes in critically ill patients: A randomized controlled trial. Liu, D. Lyu, J. Zhao, H. An, Y. PloS One 2017

Adolescent
Adult
Aged
Aged, 80 and over
Critical Illness
Deep Sedation/*adverse effects
*Emergence Delirium/chemically induced/epidemiology/physiopathology
Female
Fentanyl/administration & dosage/*adverse effects
Humans
Male
Midazolam/administration & dosage/*adverse effects
Middle Aged
Piperidines/administration & dosage/*adverse effects
Respiration, Artificial
Time Factors

Impact of dexmedetomidine on the incidence of delirium in elderly patients after cardiac surgery: A randomized controlled trial. Li, X. Yang, J. Nie, X. L. Zhang, Y. Li, X. Y. Li, L. H. Wang, D. X. Ma, D. PloS One 2017

NCT02267538
dexmedetomidine
age
aged
chemically induced
clinical trial
controlled study
double blind procedure
emergence agitation
female
heart surgery
human
incidence
male
mortality
multicenter study
postoperative period
randomized controlled trial
time factor
very elderly

Perioperative Gabapentin Does Not Reduce Postoperative Delirium in Older Surgical Patients: A Randomized Clinical Trial. Leung, J. M. Sands, L. P. Chen, N. Ames, C. Berven, S. Bozic, K. Burch, S. Chou, D. Covinsky, K. Deviren, V. Kinjo, S. Kramer, J. H. Ries, M. Tay, B. Vail, T. Weinstein, P. Chang, S. Meckler, G. Newman, S. Tsai, T. Voss, V. Youngblom, E. Anesthesiology 2017
Cerebral oximetry and postoperative delirium after cardiac surgery: a randomised, controlled trial. Lei, L. Katznelson, R. Fedorko, L. Carroll, J. Poonawala, H. Machina, M. Styra, R. Rao, V. Djaiani, G. Anaesthesia 2017

cardiac surgery
cerebral oximetry
postoperative delirium

Psychiatric symptomatology after delirium: a systematic review. Langan, C. Sarode, D. P. Russ, T. C. Shenkin, S. D. Carson, A. Maclullich, A. M. J. Psychogeriatrics 2017

anxiety
delirium
depression
post-traumatic stress disorder (PTSD)

Multicenter assessment of sedation and delirium practices in the intensive care units in Poland - is this common practice in Eastern Europe? Kotfis, K. Zegan-Barańska, M. Zukowski, M. Kusza, K. Kaczmarczyk, M. Ely, E. W. BMC Anesthesiology 2017

benzodiazepine derivative
dexmedetomidine
diazepam
fentanyl
haloperidol
midazolam
morphine
nalbuphine
oxycodone
propofol
quetiapine
remifentanil
tramadol
adult
anesthesist
article
clinical protocol
confusion assessment method for intensive care unit
delirium
drug choice
drug preference
DSM-IV
evidence based practice
human
ICD-10
intensive care
Intensive Care Delirium Screening Checklist
intensivist
monitoring
neurologic disease assessment
occupational therapy
patient safety
physiotherapy
Poland
protocol compliance
Ramsay Sedation Scale
Richmond Agitation Sedation Scale
sedation

Complications Associated With Spine Surgery in Patients Aged 80 Years or Older: Japan Association of Spine Surgeons with Ambition (JASA) Multicenter Study Kobayashi, K. Imagama, S. Ando, K. Ishiguro, N. Yamashita, M. Eguchi, Y. Matsumoto, M. Ishii, K. Hikata, T. Seki, S. Terai, H. Suzuki, A. Tamai, K. Aramomi, M. Ishikawa, T. Kimura, A. Inoue, H. Inoue, G. Miyagi, M. Saito, W. Yamada, K. Hongo, M. Nishimura Global Spine J 2017

anticoagulant agent
nonsteroid antiinflammatory agent
opiate
acute heart infarction
aged
article
bleeding
body mass
brain infarction
breathing disorder
cerebrovascular disease
delirium
diabetes mellitus
female
heart arrhythmia
hospitalization
human
hypertension
Japan
liver dysfunction
lumbar spine
major clinical study
male
multicenter study
operation duration
peroperative complication
postoperative complication
priority journal
retrospective study
risk
risk factor
severe renal impairment
spinal cord disease
spine surgery
thorax
urinary tract infection
uterine cervix
vertebral canal stenosis
very elderly

Risk Factors for Delirium After Spine Surgery in Extremely Elderly Patients Aged 80 Years or Older and Review of the Literature: Japan Association of Spine Surgeons with Ambition Multicenter Study. Kobayashi, K. Imagama, S. Ando, K. Ishiguro, N. Yamashita, M. Eguchi, Y. Matsumoto, M. Ishii, K. Hikata, T. Seki, S. Terai, H. Suzuki, A. Tamai, K. Aramomi, M. Ishikawa, T. Kimura, A. Inoue, H. Inoue, G. Miyagi, M. Saito, W. Yamada, K. Hongo, M. Matsuoka, Global Spine J 2017

complication
delirium
extremely elderly
risk factors
spine surgery

Delirium characteristics and outcomes in medical and surgical lnpatients: A subgroup analysis. Kim, S. Kim, J. J. Oh, J. Park, J. Park, J. Y. J Crit Care 2017

Delirium duration
Disease characteristics
Medical patients
Postoperative delirium
Surgical patients

Persistence of Delirium after Cessation of Sedatives and Analgesics and Impact on Clinical Outcomes in Critically Ill Patients. Kenes, M. T. Stollings, J. L. Wang, L. Girard, T. D. Ely, E. W. Pandharipande, P. P. Pharmacotherapy 2017

critical care
delirium
rapidly reversible
sedation

South Korean Family Caregiver Involvement in Delirium Care: A Qualitative Descriptive Study. Kang, Y. Moyle, W. Cooke, M. O'Dwyer, S. J Gerontol Nurs 2017
Validity of the Delirium Observation Screening Scale in Identifying Delirium in Home Hospice Patients. Jorgensen SM, Carnahan RM, Weckmann MT The American journal of hospice & palliative care 2016

delirium screening
home hospice

Discharge Plans for Geriatric Inpatients with Delirium: A Plan to Stop Antipsychotics? Johnson, K. G. Fashoyin, A. Madden-Fuentes, R. Muzyk, A. J. Gagliardi, J. P. Yanamadala, M. J Am Geriatr Soc 2017

Aged
Aged, 80 and over
Antipsychotic Agents/*therapeutic use
Delirium/*drug therapy
Female
Humans
Inpatients/psychology
Male
*Patient Discharge
*Patient Discharge Summaries
Retrospective Studies
*Withholding Treatment
antipsychotics
delirium
geriatric patients

Preoperative Risk Factors for Subsyndromal Delirium in Older Adults Who Undergo Joint Replacement Surgery. Denny, D. L. Lindseth, G. Orthop Nurs 2017
Validating the 4A's test in screening for delirium in a culturally diverse geriatric inpatient population. De, J. Wand, A. P. F. Smerdely, P. I. Hunt, G. E. Int J Geriatr Psychiatry 2017

delirium screening
dementia
diagnostic accuracy
geriatrics
non-English speaking
validation

Delirium, frailty and mortality: interactions in a prospective study of hospitalized older people. Dani, M. Owen, L. H. Jackson, T. A. Rockwood, K. Sampson, E. L. Davis, D. J Gerontol A Biol Sci Med Sci 2017

Outcomes
longevity
risk factors

Impact of inhalational versus intravenous anaesthesia on early delirium and long-term survival in elderly patients after cancer surgery: study protocol of a multicentre, open-label, and randomised controlled trial. Zhang, Y. Li, H. J. Wang, D. X. Jia, H. Q. Sun, X. D. Pan, L. H. Ye, Q. S. Ouyang, W. Jia, Z. Zhang, F. X. Guo, Y. Q. Ai, Y. Q. Zhao, B. J. Yang, X. D. Zhang, Q. G. Yin, N. Tan, H. Y. Liu, Z. H. Yu, J. B. Ma, D. BMJ Open 2017

anaesthesia in oncology
cancer
surgery
survival

Hypertonic saline for prevention of delirium in geriatric patients who underwent hip surgery. Xin, X. Xin, F. Chen, X. Zhang, Q. Li, Y. Huo, S. Chang, C. Wang, Q. J Neuroinflammation 2017

Cytokines
Elderly
Hypertonic saline
Monocytes
Neuroinflammation
Postoperative delirium

Delirium and Catatonia in Critically Ill Patients: The Delirium and Catatonia Prospective Cohort Investigation. Wilson, J. E. Carlson, R. Duggan, M. C. Pandharipande, P. Girard, T. D. Wang, L. Thompson, J. L. Chandrasekhar, R. Francis, A. Nicolson, S. E. Dittus, R. S. Heckers, S. Ely, E. W. Crit Care Med 2017

Aged
Catatonia/*diagnosis/*epidemiology
*Critical Illness
Delirium/*diagnostic imaging/*epidemiology
Female
Humans
Intensive Care Units/statistics & numerical data
Male
Middle Aged
Prospective Studies
Reproducibility of Results
Respiration, Artificial/methods
Severity of Illness Index
Vasoconstrictor Agents/administration & dosage

Ketamine for the acute management of excited delirium and agitation in the prehospital setting. Weant, K. A. Linder, L. M. Ross, C. A. Pharmacotherapy 2017

Agitation
Ketamine
emergency medicine
excited delirium
prehospital

Improved detection of delirium, implementation and validation of the CAM-ICU in elderly Emergency Department patients. Van de Meeberg EK, Festen S, Kwant M, Georg RR, Izaks GJ, Ter Maaten JC European journal of emergency medicine : official journal of the European Society for Emergency Medicine 2016
Delirium symptoms are associated with decline in cognitive function between ages 53 and 69 years: Findings from a British birth cohort study. Tsui, A. Kuh, D. Richards, M. Davis, D. Alzheimers Dement 2017

Cognitive decline
Delirium
Dementia
Life course

Delirium is associated with increased mortality in the geriatric population. Tosun Tasar, P. Sahin, S. Akcam, N. O. Dinckal, C. Ulusoy, M. G. Sarikaya, O. F. Duman, S. Akcicek, F. Noyan, A. Int J Psychiatry Clin Pract 2017

Delirium
elderly
mortality

Disturbances in Oxygen Balance During Cardiopulmonary Bypass: A Risk Factor for Postoperative Delirium. Smulter, N. Lingehall, H. C. Gustafson, Y. Olofsson, B. Engström, K. G. Appelblad, M. Svenmarker, S. J Cardiothorac Vasc Anesth 2017

aged
body surface
body weight
cardiopulmonary bypass
diagnosis
DSM-IV-TR
female
fluid balance
heart center
heart surgery
human
major clinical study
male
Mini Mental State Examination
observational study
organic brain syndrome
oxygen saturation
postoperative delirium
prospective study
risk assessment
risk factor
surgery
university hospital
vein
oxygen

Perceptions of Family Members, Nurses, and Physicians on Involving Patients' Families in Delirium Prevention. Smithburger, P. L. Korenoski, A. S. Kane-Gill, S. L. Alexander, S. A. Crit Care Nurse 2017
Perceptions of Families of Intensive Care Unit Patients Regarding Involvement in Delirium-Prevention Activities: A Qualitative Study. Smithburger, P. L. Korenoski, A. S. Alexander, S. A. Kane-Gill, S. L. Crit Care Nurse 2017
A Predictive Model of the Prevalence of Delirium in Elderly Subjects Admitted to Nursing Homes. Perez-Ros, P. Martinez-Arnau, F. M. Baixauli-Alacreu, S. Garcia-Gollarte, J. F. Tarazona-Santabalbina, F. Endocr Metab Immune Disord Drug Targets 2017

Delirium
nursing homes
older adults
patient safety
prevalence
risk factors

Incidence and Risk Factors for Postoperative Delirium in Patients After Hepatectomy. Park SA, Tomimaru Y, Shibata A, Miyagawa S, Noguchi K, Dono K World journal of surgery 2017
Five short screening tests in the detection of prevalent delirium: diagnostic accuracy and performance in different neurocognitive subgroups. O'Regan, N. A. Maughan, K. Liddy, N. Fitzgerald, J. Adamis, D. Molloy, D. W. Meagher, D. Timmons, S. Int J Geriatr Psychiatry 2017

cognition
delirium
diagnosis
evaluation studies
sensitivity and specificity

Midterm outcomes after postoperative delirium on cognition and mood in patients after cardiac surgery. Nguyen, Q. Uminski, K. Hiebert, B. M. Tangri, N. Arora, R. C. Journal of Thoracic and Cardiovascular Surgery 2017

adult
Alcohol Use Disorders Identification Test
anxiety
cognition
cohort analysis
comorbidity
coronary artery bypass graft
diagnosis
female
follow up
heart valve replacement
hospitalization
human
intensive care unit
major clinical study
male
memory disorder
Montreal cognitive assessment
mood disorder
Patient Health Questionnaire 9
postoperative delirium
postoperative period
prospective study
surgery
telephone interview

The delirium drug scale is associated to delirium incidence in the emergency department. Nguyen, Patrick Viet-Quoc Pelletier, Lucie Payot, Isabelle Latour, Judith International Psychogeriatrics 2017

delirium
aged
anticholinergic agents
emergency department
2017

Post-operative delirium is associated with increased 5-year mortality. Moskowitz, E. E. Overbey, D. M. Jones, T. S. Jones, E. L. Arcomano, T. R. Moore, J. T. Robinson, T. N. Am J Surg 2017

Aged
Colorado
Delirium/epidemiology/*mortality
Female
Humans
Incidence
Male
Middle Aged
Postoperative Complications/epidemiology/*mortality
Prospective Studies
Risk Factors
Treatment Outcome
Acute brain syndrome
Cognitive dysfunction
Confusion
Frailty
Geriatric

Worldwide Survey of the "Assessing Pain, Both Spontaneous Awakening and Breathing Trials, Choice of Drugs, Delirium Monitoring/Management, Early Exercise/Mobility, and Family Empowerment" (ABCDEF) Bundle. Morandi, A. Piva, S. Ely, E. W. Myatra, S. N. Salluh, J. I. F. Amare, D. Azoulay, E. Bellelli, G. Csomos, A. Fan, E. Fagoni, N. Girard, T. D. Heras La Calle, G. Inoue, S. Lim, C. M. Kaps, R. Kotfis, K. Koh, Y. Misango, D. Pandharipande, P. P. Permpikul, C Crit Care Med 2017

Adult
Aged
Cross-Sectional Studies
Delirium/diagnosis/therapy
Early Ambulation/statistics & numerical data
Family
Humans
Intensive Care Units/*statistics & numerical data
*Knowledge
Medicine/statistics & numerical data
Middle Aged
Pain Management
Pain Measurement
Patient Care Bundles/*methods/*utilization
Physicians/*statistics & numerical data
Respiration

Validation of an automated delirium prediction model (DElirium MOdel (DEMO)): an observational study. Mestres Gonzalvo, C. de Wit, Hajm van Oijen, B. P. C. Deben, D. S. Hurkens, Kpgm Mulder, W. J. Janknegt, R. Schols, Jmga Verhey, F. R. Winkens, B. van der Kuy, P. M. BMJ Open 2017

geriatric medicine
psychiatry

Peripheral Nerve Block as a Supplement to Light or Deep General Anesthesia in Elderly Patients Receiving Total Hip Arthroplasty: A Prospective Randomized Study. Mei, B. Zha, H. Lu, X. Cheng, X. Chen, S. Liu, X. Li, Y. Gu, E. Clin J Pain 2017
INTERDEM Academy special section: what effect does delirium have on family and nurses of older adult patients? Martins, S. Pinho, E. Correia, R. Moreira, E. Lopes, L. Paiva, J. A. Azevedo, L. Fernandes, L. Aging Ment Health 2017

Delirium
caregivers
family
nurses
psychological distress

Implementing a Multicomponent Intervention to Prevent Delirium Among Critically Ill Patients. Martinez, F. Donoso, A. M. Marquez, C. Labarca, E. Crit Care Nurse 2017
Health-Care Workers' Judgments About Pain in Older Palliative Care Patients With and Without Delirium. Mah, K. Rodin, R. A. Chan, V. W. S. Stevens, B. J. Zimmermann, C. Gagliese, L. Am J Hosp Palliat Care 2017

cancer pain
chart audit
delirium
older people
pain management
palliative care

Incidence and Risk Factors of Delirium in Patients After Type-A Aortic Dissection Surgery. Liu, Z. Pang, X. Zhang, X. Cao, G. Fang, C. Wu, S. J Cardiothorac Vasc Anesth 2017

delirium
incidence
risk factors
type-A aortic dissection

Comparison of regional with general anaesthesia on postoperative delirium (RAGA-delirium) in the older patients undergoing hip fracture surgery: Study protocol for a multicentre randomised controlled trial. Li, T. Yeung, J. Li, J. Zhang, Y. Melody, T. Gao, Y. Wang, Y. Lian, Q. Gao, F. BMJ Open 2017

NCT02213380
etomidate
fentanyl
isoflurane
local anesthetic agent
nitrous oxide
propofol
sevoflurane
sufentanil
adult
aged
article
China
controlled study
cost effectiveness analysis
epidural anesthesia
general anesthesia
health care cost
hip fracture
hospitalization
human
intermethod comparison
major clinical study
multicenter study
outcome assessment
pain
pain assessment
postoperative delirium
prospective study
quality of life
randomized controlled trial
regional anesthesia
spinal anesthesia

Factors Related to the Severity of Delirium in the Elderly Patients With Infection. Kuswardhani, R. A. T. Sugi, Y. S. Gerontol Geriatr Med 2017

delirium
elderly
infection

Decreasing Delirium through Music (DDM) in critically ill, mechanically ventilated patients in the intensive care unit: study protocol for a pilot randomized controlled trial. Khan, S. H. Wang, S. Harrawood, A. Martinez, S. Heiderscheit, A. Chlan, L. Perkins, A. J. Tu, W. Boustani, M. Khan, B. Trials 2017

Critical care
Delirium
Music

Sinai Abbreviated Geriatric Evaluation: Development and Validation of a Practical Test. Katlic, M. R. Coleman, J. Khan, K. Wozniak, S. E. Abraham, J. H. Ann Surg 2017
Structured interdisciplinary bedside rounds do not reduce length of hospital stay and 28-day re-admission rate among older people hospitalised with acute illness: an Australian study. Huynh, E. Basic, D. Gonzales, R. Shanley, C. Aust Health Rev 2017
Cerebrospinal Fluid S100B and Alzheimer’s Disease Biomarkers in Hip Fracture Patients with Delirium. Hov, K. R. Bolstad, N. Idland, A. V. Zetterberg, H. Blennow, K. Chaudhry, F. A. Frihagen, F. Ræder, J. Wyller, T. B. Watne, L. O. Dementia and Geriatric Cognitive Disorders Extra 2017

adult
Alzheimer disease
astrocyte
cerebrospinal fluid
cohort analysis
consensus
delirium
diagnosis
elective surgery
electrochemiluminescence
enzyme linked immunosorbent assay
female
hip fracture
human
major clinical study
male
pathology
prospective study
spinal anesthesia
university hospital
biological marker
endogenous compound
protein S100B
tau protein

Effect of various antipsychotic regimens on incidence of delirium in critically ill adults. Hawkins, W. A. Phan, S. V. Campbell, S. L. J Crit Care 2017

Antipsychotic agents
Critical illness
Delirium
Intensive care units
Prevention

2-(18)F-fluoro-2-deoxyglucose positron emission tomography in delirium. Haggstrom, L. R. Nelson, J. A. Wegner, E. A. Caplan, G. A. J Cereb Blood Flow Metab 2017

Aged
Aged, 80 and over
Attention
Delirium/*diagnostic imaging/metabolism
Female
*Fluorodeoxyglucose F18
Glucose/metabolism
Gyrus Cinguli/diagnostic imaging/metabolism
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging
Male
Neuropsychological Tests
Positron-Emission Tomography/*methods
Prospective Studies
*Radiopharmaceuticals
Fluorodeoxyglucose F18
cerebral metabolism
delirium
functional neuroimaging
positron emission tomography

Preoperative Serum Metabolites Are Associated With Postoperative Delirium in Elderly Hip-Fracture Patients. Guo, Y. Zhang, Y. Jia, P. Wang, W. Zhou, Q. Sun, L. Zhao, A. Zhang, X. Wang, X. Li, Y. Zhang, J. Jiang, W. J Gerontol A Biol Sci Med Sci 2017

Aged
Delirium/*epidemiology
Female
Hip Fractures/*blood/*surgery
Humans
Male
*Metabolomics
Postoperative Complications/*epidemiology
Preoperative Period
Elderly patients
Hip fracture
Metabolomics
Postoperative delirium
Risk metabolites

Delirium and effect of circadian light in the intensive care unit: a retrospective cohort study. Estrup, S. Kjer, C. K. W. Poulsen, L. M. Gogenur, I. Mathiesen, O. Acta Anaesthesiol Scand 2017
Advance Directives, Hospitalization, and Survival Among Advanced Cancer Patients with Delirium Presenting to the Emergency Department: A Prospective Study. Elsayem, A. F. Bruera, E. Valentine, A. Warneke, C. L. Wood, G. L. Yeung, S. J. Page, V. D. Silvestre, J. Brock, P. A. Todd, K. H. Oncologist 2017

Advance directives
Cancer
Delirium
Emergency
Survival

Post-operative delirium is an independent predictor of 30-day hospital readmission after spine surgery in the elderly (≥65 years old): A study of 453 consecutive elderly spine surgery patients. Elsamadicy, A. A. Wang, T. Y. Back, A. G. Lydon, E. Reddy, G. B. Karikari, I. O. Gottfried, O. N. Journal of Clinical Neuroscience 2017

acute kidney failure
aged
aging
article
cardiopulmonary arrest
deep vein thrombosis
female
heart infarction
hospital readmission
human
length of stay
lung embolism
major clinical study
male
pneumonia
postoperative delirium
priority journal
retrospective study
risk assessment
risk factor
sepsis
spine surgery
surgical infection
urinary tract infection

The Abbreviated Mental Test 4 for cognitive screening of older adults presenting to the Emergency Department. Dyer, A. H. Briggs, R. Nabeel, S. O'Neill, D. Kennelly, S. P. Eur J Emerg Med 2017
A Proactive Approach to High Risk Delirium Patients Undergoing Total Joint Arthroplasty. Duque, A. F. Post, Z. D. Orozco, F. R. Lutz, R. W. Ong, A. C. J Arthroplasty 2017

complications
delirium
perioperative screening
prevention
total joint arthroplasty

Poor Performance on a Preoperative Cognitive Screening Test Predicts Postoperative Complications in Older Orthopedic Surgical Patients. Culley, D. J. Flaherty, D. Fahey, M. C. Rudolph, J. L. Javedan, H. Huang, C. C. Wright, J. Bader, A. M. Hyman, B. T. Blacker, D. Crosby, G. Anesthesiology 2017

Age Factors
Aged
Aged, 80 and over
Cognition Disorders/diagnosis/psychology
Delirium/*diagnosis/etiology/*psychology
Female
Humans
Length of Stay/trends
Male
Neuropsychological Tests
Orthopedic Procedures/*adverse effects/trends
Postoperative Complications/*diagnosis/etiology/*psychology
Predictive Value of Tests
Preoperative Care/*methods
Prospective Studies

Early postoperative delirium after hemiarthroplasty in elderly patients aged over 70 years with displaced femoral neck fracture. Choi, Y. H. Kim, D. H. Kim, T. Y. Lim, T. W. Kim, S. W. Yoo, J. H. Clin Interv Aging 2017

delirium
elderly patients
femoral neck fracture
hemiarthroplasty

Effect of short-term exposure to ambient air particulate matter on incidence of delirium in a surgical population. Che, L. Li, Y. Gan, C. Sci Rep 2017
Subsyndromal Delirium and Institutionalization Among Patients With Critical Illness. Brummel, N. E. Boehm, L. M. Girard, T. D. Pandharipande, P. P. Jackson, J. C. Hughes, C. G. Patel, M. B. Han, J. H. Vasilevskis, E. E. Thompson, J. L. Chandrasekhar, R. Bernard, G. R. Dittus, R. S. Ely, E. W. Am J Crit Care 2017