What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Screening for delirium after surgery: validation of the 4 A's test (4AT) in the post-anaesthesia care unit.
- Authors
- Saller, T. MacLullich, A. M. J. Schafer, S. T. Crispin, A. Neitzert, R. Schule, C. von Dossow, V. Hofmann-Kiefer, K. F.
- Year
- 2019
- Journal
- Anaesthesia
- Abstract
Postoperative delirium is common and has multiple adverse consequences. Guidelines recommend routine screening for postoperative delirium beginning in the post-anaesthesia care unit. The 4 A’s test (4AT) is a widely used assessment tool for delirium but there are no studies evaluating its use in the post-anaesthesia care unit. We evaluated the performance of the 4AT in the post-anaesthesia care unit in a tertiary German medical centre. Adults who were able to provide informed consent, were not scheduled for postoperative intensive care, and who did not have dementia or severe neuropsychiatric disorders underwent screening by trained research staff with the Nurse Delirium Screening Scale and a new German translation of the 4AT in a random order at the point of discharge from the post-anaesthesia care unit. Reference standard assessment of delirium was psychiatric evaluation by experienced clinicians. Five hundred and forty-three patients (mean age (SD) 52 (18) years) were analysed; 22 (4.1%) patients developed delirium. The sensitivity and specificity of the 4AT were 95.5% (95%CI 77.2-99.9) and 99.2% (95%CI 98.1-99.8), respectively. The area under the receiver operator characteristic curve was 0.998 (95%CI 0.995-1.000). The Nursing Delirium Screening Scale had a sensitivity of 27.3% (95%CI 10.7-50.2) and specificity of 99.4% (95%CI 98.3-99.9), with an area under the curve of 0.761 (95%CI 0.629-0.894). These findings suggest that the 4AT is an effective and robust instrument for delirium detection in the post-anaesthesia care unit.
- PMID
- Keywords
delirium
post-anaesthesia care unit
postoperative complications
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Age is the Most Significantly Associated Risk Factor with the Development of Delirium in Patients Hospitalized for More Than Five Days in Surgical Wards: Retrospective Cohort Study. | Kubota K, Suzuki A, Ohde S, Yamada U, Hosaka T, Okuno F, Fujitani I, Koitabashi A, Shimada G, Kishida A | Annals of surgery | 2017 |
nitrogen |
| Reduced ex vivo release of pro-inflammatory cytokines and elevated plasma interleukin-6 are inflammatory signatures of post-stroke delirium. | Kowalska, K. Klimiec, E. Weglarczyk, K. Pera, J. Slowik, A. Siedlar, M. Dziedzic, T. | J Neuroinflammation | 2018 |
Cytokines |
| Parkinson's disease-related non-motor features as risk factors for post-operative delirium in spinal surgery. | Kim, K. H. Kang, S. Y. Shin, D. A. Yi, S. Ha, Y. Kim, K. N. Sohn, Y. H. Lee, P. H. | PLoS One | 2018 | |
| Relationships between markers of neurologic and endothelial injury during critical illness and long-term cognitive impairment and disability. | Hughes, C. G. Patel, M. B. Brummel, N. E. Thompson, J. L. McNeil, J. B. Pandharipande, P. P. Jackson, J. C. Chandrasekhar, R. Ware, L. B. Ely, E. W. Girard, T. D. | Intensive Care Medicine | 2018 |
NCT00392795 |
| Incidence, Risk Factors, and Sequelae of Post-kidney Transplant Delirium. | Haugen, C. E. Mountford, A. Warsame, F. Berkowitz, R. Bae, S. G. Thomas A Brown, C. H. th Brennan, D. C. Neufeld, K. J. Carlson, M. C. Segev, D. L. McAdams-DeMarco, M. | J Am Soc Nephrol | 2018 |
clinical |
| Evaluation of an Intervention With Nurses for Delirium Detection After Cardiac Surgery. | Fraser, V. Cossette, S. Mailhot, T. Brisebois, A. Dubé, V. | Worldviews on evidence-based nursing | 2018 |
adult |
| Delirium clinical motor subtypes: a narrative review of the literature and insights from neurobiology. | FitzGerald JM | Aging & mental health | 2017 |
Screening and diagnosis |
| Are antipsychotics effective for the prevention of postoperative delirium? | Castro, V. Guinguis, R. Carrasco, M. | Medwave | 2018 | |
| Measuring mobility in older hospital patients with cognitive impairment using the de Morton Mobility Index. | Braun, T. Gruneberg, C. Thiel, C. Schulz, R. J. | BMC Geriatr | 2018 |
Dementia |
| Haloperidol for delirium in critically ill patients – protocol for a systematic review. | Barbateskovic, M. Kraus, S. R. Collet, M. O. Mathiesen, O. Jakobsen, J. C. Perner, A. Wetterslev, J. | Acta Anaesthesiol Scand | 2018 |
haloperidol |
| Dexmedetomidine vs morphine and midazolam in the prevention and treatment of delirium after adult cardiac surgery; a randomized, double-blinded clinical trial. | Azeem, T. M. A. Yosif, N. E. Alansary, A. M. Esmat, I. M. Mohamed, A. K. | Saudi J Anaesth | 2018 |
Dexmedetomidine |
| Psychometric properties of the Arabic version of the confusion assessment method for the intensive care unit (CAM-ICU). | Aljuaid, M. H. Deeb, A. M. Dbsawy, M. Alsayegh, D. Alotaibi, M. Arabi, Y. M. | BMC Psychiatry | 2018 |
Arabic |
| Postoperative delirium, learning, and anesthetic neurotoxicity: Some perspectives and directions. | Mutch, W. A. El-Gabalawy, R. M. Graham, M. R. | Frontiers in Neurology | 2018 |
adult |
| Designing a nurse-delivered delirium bundle: What intensive care unit staff, survivors, and their families think? | Bannon, L. McGaughey, J. Clarke, M. McAuley, D. F. Blackwood, B. | Aust Crit Care | 2018 |
Delirium |
| The 2014 updated version of the Confusion Assessment Method for the Intensive Care Unit compared to the 5th version of the Diagnostic and Statistical Manual of Mental Disorders and other current methods used by intensivists. | Chanques, G. Ely, E. W. Garnier, O. Perrigault, F. Eloi, A. Carr, J. Rowan, C. M. Prades, A. de Jong, A. Moritz-Gasser, S. Molinari, N. Jaber, S. | Ann Intensive Care | 2018 |
Critical care |
| Effect of a 24-h extended visiting policy on delirium in critically ill patients. | Westphal, G. A. Moerschberger, M. S. Vollmann, D. D. Inacio, A. C. Machado, M. C. Sperotto, G. Cavalcanti, A. B. Koenig, A. | Intensive Care Medicine | 2018 | |
| Effect of Sedation Regimen on Weaning from Mechanical Ventilation in the Intensive Care Unit. | Nunes, S. L. Forsberg, S. Blomqvist, H. Berggren, L. Sorberg, M. Sarapohja, T. Wickerts, C. J. | Clin Drug Investig | 2018 | |
| Validation of the korean version of the delirium motor subtype scale. | Kim, H. Lee, M. Kwon, I. S. Kim, J. L. | Psychiatry Investigation | 2018 |
aged |
| e-Screening revolution: A novel approach to developing a delirium screening tool in the intensive care unit. | Eeles, E. Gunn, H. Sutt, A. L. Pinsker, D. Flaws, D. Jarrett, P. Lye, I. Fraser, J. F. | Australasian Journal on Ageing | 2018 |
delirium |
| Sedation Intensity in the First 48 Hours of Mechanical Ventilation and 180-Day Mortality: A Multinational Prospective Longitudinal Cohort Study. | Shehabi, Y. Bellomo, R. Kadiman, S. Ti, L. K. Howe, B. Reade, M. C. Khoo, T. M. Alias, A. Wong, Y. L. Mukhopadhyay, A. McArthur, C. Seppelt, I. Webb, S. A. Green, M. Bailey, M. J. | Crit Care Med | 2018 | |
| Screening for delirium with the Intensive Care Delirium Screening Checklist (ICDSC): a re-evaluation of the threshold for delirium. | Boettger, S. Garcia Nunez, D. Meyer, R. Richter, A. Rudiger, A. Schubert, M. Jenewein, J. | Swiss Medical Weekly | 2018 | |
| Risk Factors of Postoperative Delirium in the Intensive Care Unit After Liver Transplantation. | Lee, H. Oh, S. Y. Yu, J. H. Kim, J. Yoon, S. Ryu, H. G. | World J Surg | 2018 | |
| Risk Factors for Postoperative Delirium After Deep Brain Stimulation Surgery for Parkinson's Disease. | Tanaka, M. Tani, N. Maruo, T. Oshino, S. Hosomi, K. Saitoh, Y. Kishima, H. | World Neurosurg | 2018 |
Deep Brain Stimulation |
| The relationship of delirium and risk factors in cardiology intensive care unit patients with the nursing workload. | Ozturk Birge, A. Beduk, T. | J Clin Nurs | 2018 |
Critical Care |
| Protocol for a single-centre prospective observational study of postoperative delirium following total joint arthroplasties among South East Asians. | Abdullah, H. R. Tan, S. R. Lee, S. J. Bin Abd Razak, H. R. Seet, R. H. Ying, H. Sethi, E. Sim, E. Y. | BMJ Open | 2018 |
*delirium |
| Preoperative statins are associated with a reduced risk of postoperative delirium following vascular surgery. | Lee, D. S. Lee, M. Y. Park, C. M. Kim, D. I. Kim, Y. W. Park, Y. J. | PLoS One | 2018 | |
| Predisposing and precipitating factors for delirium in community-dwelling older adults admitted to hospital with this condition: A prospective case series. | Magny, E. Le Petitcorps, H. Pociumban, M. Bouksani-Kacher, Z. Pautas, É Belmin, J. Bastuji-Garin, S. Lafuente-Lafuente, C. | PLoS One | 2018 |
aged |
| Predicting excess cost for older inpatients with clinical complexity: A retrospective cohort study examining cognition, comorbidities and complications | Bail, K. Draper, B. Berry, H. Karmel, R. Goss, J. | PLoS One | 2018 |
adult |
| Pilot Study of a Two-Step Delirium Detection Protocol Administered By Certified Nursing Assistants, Physicians, and Registered Nurses. | Fick, D. M. Inouye, S. K. McDermott, C. Zhou, W. Ngo, L. Gallagher, J. McDowell, J. Penrod, J. Siuta, J. Covaleski, T. Marcantonio, E. R. | J Gerontol Nurs | 2018 | |
| Perioperative hyperglycaemia and neurocognitive outcome after surgery: a systematic review. | Hermanides, J. Qeva, E. Preckel, B. Bilotta, F. | Minerva Anestesiol | 2018 | |
| Low-dose Nocturnal Dexmedetomidine Prevents ICU Delirium: A Randomized, Placebo-controlled Trial. | Skrobik, Y. Duprey, M. S. Hill, N. S. Devlin, J. W. | Am J Respir Crit Care Med | 2018 |
delirium, sleep, intensive care, dexmedetomidine, randomized controlled trial |
| Low peripheral levels of insulin growth factor-1 are associated with high incidence of delirium among elderly patients: A systematic review and meta-analysis. | Li, D. J. Tseng, P. T. Stubbs, B. Chen, T. Y. Lin, P. Y. Chen, S. L. Thompson, T. Adamis, D. Chu, C. S. | Arch Gerontol Geriatr | 2018 |
Biomarker |
| Is anemia associated with cognitive impairment and delirium among older acute surgical patients? | Myint, P. K. Owen, S. McCarthy, K. Pearce, L. Moug, S. J. Stechman, M. J. Hewitt, J. Carter, B. | Geriatrics & Gerontology International | 2018 |
anemia |
| Intraoperative Sedation With Dexmedetomidine is Superior to Propofol for Elderly Patients Undergoing Hip Arthroplasty: A Prospective Randomized Controlled Study. | Mei, B. Meng, G. Xu, G. Cheng, X. Chen, S. Zhang, Y. Zhang, M. Liu, X. Gu, E. | Clin J Pain | 2018 | |
| Infrared pupillometry helps to detect and predict delirium in the post-anesthesia care unit. | Yang E, Kreuzer M, Hesse S, Davari P, Lee SC, García PS | Journal of clinical monitoring and computing | 2017 |
PLR-200 |
| Influence of Physical Restraint on Delirium of Adult Patients in ICU: A Nested Case-Control Study. | Pan, Y. Jiang, Z. Changrong, Y. Wang, L. Zhang, J. Zhou, J. Tao, M. Quan, M. Wu, Q. | J Clin Nurs | 2018 |
Delirium |
| Incidence of delirium in the Canadian emergency department and its consequences on hospital length of stay: A prospective observational multicentre cohort study. | Émond, M. Boucher, V. Carmichael, P. H. Voyer, P. Pelletier, M. Gouin, É Daoust, R. Berthelot, S. Lamontagne, M. E. Morin, M. Lemire, S. Minh Vu, T. T. Nadeau, A. Rheault, M. Juneau, L. Le Sage, N. Lee, J. | BMJ Open | 2018 |
aged |
| Impact of timing and duration of postoperative delirium: a retrospective observational study | Lee, H. Ju, J. W. Oh, S. Y. Kim, J. Jung, C. W. Ryu, H. G. | Surgery | 2018 | |
| Frequency and risk factors for subsyndromal delirium in an intensive care unit. | Yamada, C. Iwawaki, Y. Harada, K. Fukui, M. Morimoto, M. Yamanaka, R. | Intensive Crit Care Nurs | 2018 |
Delirium |
| Focusing on Inattention: The Diagnostic Accuracy of Brief Measures of Inattention for Detecting Delirium. | Marra, A. Jackson, J. C. Ely, E. W. Graves, A. J. Schnelle, J. F. Dittus, R. S. Wilson, A. Han, J. H. | J Hosp Med | 2018 | |
| Feasibility of Cognitive Training in Critically Ill Patients: A Pilot Study. | Wassenaar, A. Rood, P. Boelen, D. Schoonhoven, L. Pickkers, P. van den Boogaard, M. | Am J Crit Care | 2018 | |
| Evaluation of a sound environment intervention in an ICU: A feasibility study. | Johansson, L. Lindahl, B. Knutsson, S. Ogren, M. Persson Waye, K. Ringdal, M. | Aust Crit Care | 2018 |
Complex intervention |
| Effects of Haloperidol on Delirium in Adult Patients: A Systematic Review and Meta-analysis. | Shen, Y. Z. Peng, K. Zhang, J. Meng, X. W. Ji, F. | Med Princ Pract | 2018 | |
| The effect of the timing and dose of dexmedetomidine on postoperative delirium in elderly patients after laparoscopic major non-cardiac surgery: A double blind randomized controlled study. | Lee, C. Lee, C. H. Lee, G. Lee, J. Hwang, J. | J Clin Anesth | 2018 |
Cytokine |
| Effect of organisational factors on the variation in incidence of delirium in intensive care unit patients: A systematic review and meta-regression analysis. | Rood, P. Huisman-de Waal, G. Vermeulen, H. Schoonhoven, L. Pickkers, P. van den Boogaard, M. | Aust Crit Care | 2018 |
Critical care |
| Effect of Administration of Ramelteon, a Melatonin Receptor Agonist, on the Duration of Stay in the ICU: A Single-Center Randomized Placebo-Controlled Trial. | Nishikimi, M. Numaguchi, A. Takahashi, K. Miyagawa, Y. Matsui, K. Higashi, M. Makishi, G. Matsui, S. Matsuda, N. | Crit Care Med | 2018 | |
| Diagnostic accuracy of delirium assessment methods in critical care patients | Barman, A. Pradhan, D. Bhattacharyya, P. Dey, S. Bhattacharjee, A. Tesia, S. S. Mitra, J. K. | Journal of Critical Care | 2018 |
Acute Physiology and Chronic Health Evaluation II |
| Delirium in ICU Patients Following Cardiac Surgery: An Observational Study. | Simeone, S. Pucciarelli, G. Perrone, M. Rea, T. Gargiulo, G. Guillari, A. Castellano, G. Di Tommaso, L. Niola, M. Iannelli, G. | J Clin Nurs | 2018 |
Icu |
| Clinical phenotypes of delirium during critical illness and severity of subsequent long-term cognitive impairment: a prospective cohort study. | Girard, T. D. Thompson, J. L. Pandharipande, P. P. Brummel, N. E. Jackson, J. C. Patel, M. B. Hughes, C. G. Chandrasekhar, R. Pun, B. T. Boehm, L. M. Elstad, M. R. Goodman, R. B. Bernard, G. R. Dittus, R. S. Ely, E. W. | Lancet Respir Med | 2018 | |
| Postoperative Complications Associated With Spine Surgery in Patients Older Than 90 Years: A Multicenter Retrospective Study. | Kobayashi, K. Imagama, S. Sato, K. Kato, F. Kanemura, T. Yoshihara, H. Sakai, Y. Shinjo, R. Hachiya, Y. Osawa, Y. Matsubara, Y. Ando, K. Nishida, Y. Ishiguro, N. | Global Spine J | 2018 |
complications |
| Do the Phenotypes of Symptom Fluctuation Differ Among Motor Subtypes in Patients With Delirium?. | Kim, S. Y. Kim, J. M. Kim, S. W. Kim, E. S. Kang, H. J. Lee, J. Y. Bae, K. Y. Shin, I. S. Yoon, J. S. | J Pain Symptom Manage | 2018 |
Delirium |
| Delirium and its consequences in the specialized palliative care unit: Validation of the Korean version of Memorial Delirium Assessment Scale. | Kang, B. Kim, Y. J. Suh, S. W. Son, K. L. Ahn, G. S. Park, H. Y. | Psycho-Oncology | 2018 |
adult |
| The Motoric Types of Delirium and Estimated Blood Loss during Perioperative Period in Orthopedic Elderly Patients. | Hong, N. Park, J. Y. | Biomed Res Int | 2018 | |
| CSF sTREM2 in delirium-relation to Alzheimer's disease CSF biomarkers Abeta42, t-tau and p-tau. | Henjum, K. Quist-Paulsen, E. Zetterberg, H. Blennow, K. Nilsson, L. N. G. Watne, L. O. | J Neuroinflammation | 2018 |
Alzheimer’s disease |
| CSF biomarkers in delirium: a systematic review. | Hall RJ, Watne LO, Cunningham E, Zetterberg H, Shenkin SD, Wyller TB, MacLullich AMJ | International journal of geriatric psychiatry | 2017 |
CSF biomarkers |
| Prediction of ICU Delirium: Validation of Current Delirium Predictive Models in Routine Clinical Practice. | Green, C. Bonavia, W. Toh, C. Tiruvoipati, R. | Crit Care Med | 2018 | |
| The Incidence of Recorded Delirium Episodes Before and After Dementia Diagnosis: Differences Between Dementia With Lewy Bodies and Alzheimer's Disease. | FitzGerald, J. M. Perera, G. Chang-Tave, A. Price, A. Rajkumar, A. P. Bhattarai, M. O'Brien, J. T. Ballard, C. Aarsland, D. Stewart, R. Mueller, C. | J Am Med Dir Assoc | 2018 |
Alzheimer’s disease |
| Pain and delirium in people with dementia in the acute general hospital setting. | Feast, A. R. White, N. Lord, K. Kupeli, N. Vickerstaff, V. Sampson, E. L. | Age Ageing | 2018 | |
| Environmental factors and risk of delirium in geriatric patients: an observational study. | Evensen, S. Saltvedt, I. Lydersen, S. Wyller, T. B. Taraldsen, K. Sletvold, O. | BMC Geriatr | 2018 |
Delirium |
| Validity of a screening method for delirium risk in older patients admitted to a general hospital in the Netherlands. | Ettema, R. Heim, N. Hamaker, M. Emmelot-Vonk, M. van der Mast, R. Schuurmans, M. | General Hospital Psychiatry | 2018 |
aged |
| Indwelling urinary catheters, aortic valve treatment and delirium: a prospective cohort study. | Eide, L. S. Ranhoff, A. H. Lauck, S. Fridlund, B. Haaverstad, R. Hufthammer, K. O. Kuiper, K. K. J. Nordrehaug, J. E. Norekval, T. M. | BMJ Open | 2018 |
Savr |
| Diagnostic value of NT-proCNP compared to NSE and S100B in cerebrospinal fluid and plasma of patients with sepsis-associated encephalopathy. | Ehler, J. Saller, T. Wittstock, M. Rommer, P. S. Chappell, D. Zwissler, B. Grossmann, A. Richter, G. Reuter, D. A. Noldge-Schomburg, G. Sauer, M. | Neurosci Lett | 2018 |
Biomarker |
| Exploration of Relationships Between Postoperative Pain and Subsyndromal Delirium in Older Adults. | Denny, D. L. Such, T. L. | Nurs Res | 2018 | |
| Prediction of Incident Delirium Using a Random Forest classifier. | Corradi, J. P. Thompson, S. Mather, J. F. Waszynski, C. M. Dicks, R. S. | J Med Syst | 2018 |
Decision support |
| The hip fracture surgery in elderly patients (HIPELD) study to evaluate xenon anaesthesia for the prevention of postoperative delirium: a multicentre, randomized clinical trial. | Coburn, M. Sanders, R. D. Maze, M. Nguyên-Pascal, M. L. Rex, S. Garrigues, B. Carbonell, J. A. Garcia-Perez, M. L. Stevanovic, A. Kienbaum, P. Neukirchen, M. Schaefer, M. S. Borghi, B. van Oven, H. Tognù, A. Al Tmimi, L. Eyrolle, L. Langeron, O. Capdevi | British Journal of Anaesthesia | 2018 |
C reactive protein |
| Effect of a single pre-operative 125 mg dose of methylprednisolone on postoperative delirium in hip fracture patients; a randomised, double-blind, placebo-controlled trial. | Clemmesen, C. G. Lunn, T. H. Kristensen, M. T. Palm, H. Foss, N. B. | Anaesthesia | 2018 |
delirium |
| Identifying Patterns of Delirium in Hospitalized Patients on Dexamethasone Using a Chart Abstraction Tool. | Chang, J. T. Atayee, R. S. Edmonds, K. P. | Journal of Pain and Palliative Care Pharmacotherapy | 2018 |
dexamethasone |
| Detecting delirium in elderly medical emergency patients: validation and subsequent modification of the German Nursing Delirium Screening Scale. | Brich, J. Baten, V. Wussmann, J. Heupel-Reuter, M. Perlov, E. Kloppel, S. Busch, H. J. | Intern Emerg Med | 2018 |
Delirium |
| Mobilizing older adults: A multi-site, exploratory and observational study on patients enrolled in the Hospital Elder Life Program (HELP). | Babine, R. L. Hyrkas, K. E. McKenzie, C. G. Wierman, H. R. | Geriatr Nurs | 2018 |
Older adults |
| Validation of the Stanford Proxy Test for Delirium (S-PTD) among critical and noncritical patients. | Alosaimi, F. D. Alghamdi, A. Alsuhaibani, R. Alhammad, G. Albatili, A. Albatly, L. Althomali, B. Aljamaan, F. Maldonado, J. R. | J Psychosom Res | 2018 |
Delirium |
| Impact of an Antipsychotic Discontinuation Bundle During Transitions of Care in Critically Ill Patients. | D’Angelo, R. G. Rincavage, M. Tata, A. L. Millstein, L. S. Gulati, M. S. Flurie, R. W. Gonzales, J. P. | J Intensive Care Med | 2019 |
urinary catheter |
| Living at home after emergency hospital admission: Prospective cohort study in older adults with and without cognitive spectrum disorder. | Burton, J. K. Guthrie, B. Hapca, S. M. Cvoro, V. Donnan, P. T. Reynish, E. L. | BMC Medicine | 2018 |
aged |
| The Association Between C-Reactive Protein and Postoperative Delirium Differs by Catechol-O-Methyltransferase Genotype. | Vasunilashorn, S. M. Ngo, L. H. Jones, R. N. Inouye, S. K. Hall, K. T. Gallagher, J. Dillon, S. T. Xie, Z. Libermann, T. A. Marcantonio, E. R. | American Journal of Geriatric Psychiatry | 2019 |
acute phase protein |
| Risk factors associated with acute in-hospital delirium for patients diagnosed with a hip fracture in the emergency department. | Thompson, C. Brienza, V. J. M. Sandre, A. Caine, S. Borgundvaag, B. McLeod, S. | Canadian Journal of Emergency Medicine | 2018 |
codeine |
| A Comparison of Early, Late, and No Treatment of Intensive Care Unit Delirium With Antipsychotics: A Retrospective Cohort Study. | Thom, R. P. Bui, M. P. Rosner, B. Teslyar, P. Levy-Carrick, N. C. Klompas, M. | The Primary Care Companion for CNS Disorders | 2018 |
neuroleptic agent |
| Postoperative Pain Management Strategies and Delirium After Transapical Aortic Valve Replacement: A Randomized Controlled Trial. | Strike, E. Arklina, B. Stradins, P. Cusimano, R. J. Osten, M. Horlick, E. Styra, R. Poonawala, H. Carroll, J. Djaiani, G. | Journal of Cardiothoracic and Vascular Anesthesia | 2018 |
adult |
| Effect of Depth of Sedation in Older Patients Undergoing Hip Fracture Repair on Postoperative Delirium: The STRIDE Randomized Clinical Trial. | Sieber, F. E. Neufeld, K. J. Gottschalk, A. Bigelow, G. E. Oh, E. S. Rosenberg, P. B. Mears, S. C. Stewart, K. J. Ouanes, J. P. P. Jaberi, M. Hasenboehler, E. A. Li, T. Wang, N. Y. | JAMA Surg | 2018 |
local anesthetic agent |
| Incidence of Delirium in Critically Ill Cancer Patients. | Sánchez-Hurtado, L. A. Hernández-Sánchez, N. Del Moral-Armengol, M. Guevara-García, H. García-Guillén, F. J. Herrera-Gómez, Á Ñamendys-Silva, S. A. | Pain Research & Management | 2018 |
adult |
| Dispersion in Scores on the Richmond Agitation and Sedation Scale as a Measure of Delirium in Patients with Subdural Hematomas. | Robinson, D. Thompson, S. Bauerschmidt, A. Melmed, K. Couch, C. Park, S. Agarwal, S. Roh, D. Connolly, E. S. Claassen, J. | Neurocritical Care | 2018 |
adult |
| Underdiagnosis of delirium in the elderly in acute care hospital settings: lessons not learned. | Ritter, S. R. F. Cardoso, A. F. Lins, M. M. P. Zoccoli, T. L. V. Freitas, M. P. D. Camargos, E. F. | Psychogeriatrics | 2018 |
aged |
| Risk Factors and Hospital Mortality in Surgical and Non-surgical Patients with Delirium. | Restrepo, D. Duque, M. Montoya, L. Berrouet, M. C. Rojas, M. Lopera, G. Giraldo, K. | Revista Colombiana de Psiquiatria | 2018 |
cholinergic receptor blocking agent |
| Caring for Critically Ill Patients with the ABCDEF Bundle: Results of the ICU Liberation Collaborative in Over 15,000 Adults. | Pun, B. T. Balas, M. C. Barnes-Daly, M. A. Thompson, J. L. Aldrich, J. M. Barr, J. Byrum, D. Carson, S. S. Devlin, J. W. Engel, H. J. Esbrook, C. L. Hargett, K. D. Harmon, L. Hielsberg, C. Jackson, J. C. Kelly, T. L. Kumar, V. Millner, L. Morse, A. Perme, | Crit Care Med | 2019 |
adult |
| Effects of Perioperative Dexmedetomidine on Postoperative Mortality and Morbidity: A Systematic Review and Meta-analysis | Peng, K. Ji, F. H. Liu, H. Y. Zhang, J. Chen, Q. C. Jiang, Y. H. | Clinical Therapeutics | 2018 |
adult |
| Relation Between Delirium and Anticholinergic Drug Burden in a Cohort of Hospitalized Older Patients: An Observational Study. | Pasina, L. Colzani, L. Cortesi, L. Tettamanti, M. Zambon, A. Nobili, A. Mazzone, A. Mazzola, P. Annoni, G. Bellelli, G. | Drugs Aging | 2018 |
adverse event |
| Neopterin and mini-mental state examination scores, two independent risk factors for postoperative delirium in elderly patients with open abdominal surgery. | Miao, S. Shen, P. Zhang, Q. Wang, H. Shen, J. Wang, G. Lv, D. | Journal of Cancer Research and Therapeutics | 2018 |
C reactive protein |
| Reliability and accuracy of delirium assessments among investigators at multiple international centres. | Maybrier, H. R. Mickle, A. M. Escallier, K. E. Lin, N. Schmitt, E. M. Upadhyayula, R. T. Wildes, T. S. Mashour, G. A. Palihnich, K. Inouye, S. K. Avidan, M. S. | BMJ Open | 2018 |
NCT01690988 |
| Does the melatonin receptor 1B gene polymorphism have a role in postoperative delirium? | Mahanna-Gabrielli, E. Miano, T. A. Augoustides, J. G. Kim, C. Bavaria, J. E. Andrew Kofke, W. | PLoS ONE | 2018 |
adult |
| Volatile anaesthetics and postoperative delirium in older surgical patients—A secondary analysis of prospective cohort studies | Kinjo, S. Lim, E. Magsaysay, M. V. Sands, L. P. Leung, J. M. | Acta Anaesthesiol Scand | 2019 |
desflurane |
| Addition of Suvorexant to Ramelteon Therapy for Improved Sleep Quality with Reduced Delirium Risk in Acute Stroke Patients. | Kawada, K. Ohta, T. Tanaka, K. Miyamura, M. Tanaka, S. | Journal of Stroke and Cerebrovascular Diseases | 2019 |
phosphorus 33 |
| Age-dependent morbidity and mortality outcomes after surgical aortic valve replacement. | Hussain, A. I. Auensen, A. Brunborg, C. Beitnes, J. O. Gullestad, L. Pettersen, K. I. | Interactive cardiovascular and thoracic surgery | 2018 |
NCT01794832 |
| Interventions for preventing intensive care unit delirium in adults. | Herling, S. F. Greve, I. E. Vasilevskis, E. E. Egerod, I. Bekker Mortensen, C. Møller, A. M. Svenningsen, H. Thomsen, T. | Cochrane Database of Systematic Reviews | 2018 |
ISRCTN83567338 |
| Mortality in people with dementia, delirium, and unspecified cognitive impairment in the general hospital: Prospective cohort study of 6,724 patients with 2 years follow-up. | Hapca, S. Guthrie, B. Cvoro, V. Bu, F. Rutherford, A. C. Reynish, E. Donnan, P. T. | Clinical Epidemiology | 2018 |
aged |
| Neurofilament Light in the Serum and Cerebrospinal Fluid of Hip Fracture Patients with Delirium. | Halaas, N. B. Blennow, K. Idland, A. V. Wyller, T. B. Ræder, J. Frihagen, F. Staff, A. C. Zetterberg, H. Watne, L. O. | Dementia and Geriatric Cognitive Disorders | 2018 |
aged |
| Investigating speech and language impairments in delirium: A preliminary case-control study. | Green, S. Reivonen, S. Rutter, L. M. Nouzova, E. Duncan, N. Clarke, C. MacLullich, A. M. J. Tieges, Z. | PLoS One | 2018 |
aged |
| Elevated serum S-100β in patients with septic shock is associated with delirium. | Erikson, K. Ala-Kokko, T. I. Koskenkari, J. Liisanantti, J. H. Kamakura, R. Herzig, K. H. Syrjälä, H. | Acta Anaesthesiol Scand | 2019 |
interleukin 6 |
| A prospective, observational study of cerebrovascular autoregulation and its association with delirium following cardiac surgery. | Chan, B. Aneman, A. | Anaesthesia | 2019 |
FORESIGHT Elite |
| Dynamic cerebral autoregulation: A marker of post-operative delirium? | Caldas, J. R. Panerai, R. B. Bor-Seng-Shu, E. Ferreira, G. S. R. Camara, L. Passos, R. H. de-Lima-Oliveira, M. Galas, F. R. B. G. Almeida, J. P. Nogueira, R. C. Mian, N. Gaiotto, F. A. Robinson, T. G. Hajjar, L. A. | Clinical Neurophysiology | 2018 |
NCT02143544 |
| The Golden Angels: Effects of trained volunteers on specialling and readmission rates for people with dementia and delirium in rural hospitals. | Blair, A. Anderson, K. Bateman, C. | International Psychogeriatrics | 2018 |
hearing aid |
| The effectiveness of non-pharmacological interventions in reducing the incidence and duration of delirium in critically ill patients: a systematic review and meta-analysis. | Bannon, L. McGaughey, J. Verghis, R. Clarke, M. McAuley, D. F. Blackwood, B. | Intensive Care Medicine | 2018 |
adult |
| Blood Thiamine Level and Cognitive Function in Older Hospitalized Patients. | Pourhassan, M. Angersbach, B. Lueg, G. Klimek, C. N. Wirth, R. | J Geriatr Psychiatry Neurol | 2018 |
delirium |