What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Comparison of the frailty index and frailty phenotype and their associations with postoperative delirium incidence and severity
- Authors
- Deiner, S. G. Marcantonio, E. R. Trivedi, S. Inouye, S. K. Travison, T. G. Schmitt, E. M. Hshieh, T. Fong, T. G. Ngo, L. H. Vasunilashorn, S. M.
- Year
- 2024
- Journal
- J Am Geriatr Soc
- Abstract
BACKGROUND: Recent studies have reported an association between presurgical frailty and postoperative delirium. However, it remains unclear whether the frailty-delirium relationship differs by measurement tool (e.g., frailty index vs. frailty phenotype) and whether frailty is associated with delirium, independent of preoperative cognition. METHODS: We used the successful aging after elective surgery (SAGES) study, a prospective cohort of older adults age ≥70 undergoing major non-cardiac surgery (N = 505). Preoperative measurement of the modified mini-mental (3MS) test, frailty index and frailty phenotype were obtained. The confusion assessment method (CAM), supplemented by chart review, identified postoperative delirium. Delirium feature severity was measured by the sum of CAM-severity (CAM-S) scores. Generalized linear models were used to determine the relative risk of each frailty measure with delirium incidence and severity. Subsequent models adjusted for age, sex, surgery type, Charlson comorbidity index, and 3MS. RESULTS: On average, patients were 76.7 years old (standard deviation 5.22), 58.8% of women. For the frailty index, the incidence of delirium was 14% in robust, 17% in prefrail, and 31% in frail patients (p < 0.001). For the frailty phenotype, delirium incidence was 13% in robust, 21% in prefrail, and 27% in frail patients (p = 0.016). Frailty index, but not phenotype, was independently associated with delirium after adjustment for comorbidities (relative risk [RR] 2.13, 95% confidence interval [CI] 1.23-3.70; RR 1.61, 95% CI 0.77-3.37, respectively). Both frailty measures were associated with delirium feature severity. After adjustment for preoperative cognition, only the frailty index was associated with delirium incidence; neither index nor phenotype was associated with delirium feature severity. CONCLUSION: Both the frailty index and phenotype were associated with the development of postoperative delirium. The index showed stronger associations that remained significant after adjusting for baseline comorbidities and preoperative cognition. Measuring frailty prior to surgery can assist in identifying patients at risk for postoperative delirium.
- PMID
PMID: 37964474
PMCID: PMC11090994
NIHMSID: NIHMS1942228
- Keywords
Humans
Female
Male
Aged
Incidence
*Delirium/epidemiology/diagnosis
Prospective Studies
*Postoperative Complications/epidemiology
*Phenotype
*Frailty/epidemiology/diagnosis
Aged, 80 and over
Frail Elderly/statistics & numerical data
Severity of Illness Index
Geriatric Assessment/methods
Elective Surgical Procedures/adverse effects
Risk Factors
delirium
frailty index
frailty phenotype
surgery
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Impact of Delirium on Patients Hospitalized for Myocardial Infarction: a Propensity Score Analysis of The National Inpatient Sample. | Abdullah, A. Eigbire, G. Salama, A. Wahab, A. Awadalla, M. Hoefen, R. Alweis, R. | Clin Cardiol | 2018 |
ICD-9-CM codes |
| The role of geriatrician-hospitalists in the care of older adults: A retrospective cohort study. | Sinvani, L. Carney, M. Kozikowski, A. Smilios, C. Patel, V. Qiu, G. Zhang, M. Babalola, O. Kandov, Y. Rosenberg, D. Wolf-Klein, G. Pekmezaris, R. | Arch Gerontol Geriatr | 2018 |
indwelling catheter |
| Clinical and laboratory characteristics associated with referral of hospitalized elderly to palliative care. | Arcanjo, S. P. Saporetti, L. A. Curiati, J. A. E. Jacob-Filho, W. Avelino-Silva, T. J. | Einstein (Sao Paulo) | 2018 | |
| Intraoperative cerebral oximetry-based management for optimizing perioperative outcomes: a meta-analysis of randomized controlled trials. | Zorrilla-Vaca, A. Healy, R. Grant, M. C. Joshi, B. Rivera-Lara, L. Brown, C. Mirski, M. A. | Canadian Journal of Anesthesia | 2018 |
ISRCTN01707446 |
| Postoperative delirium in total knee and hip arthroplasty patients: a study of perioperative modifiable risk factors. | Weinstein, S. M. Poultsides, L. Baaklini, L. R. Mörwald, E. E. Cozowicz, C. Saleh, J. N. Arrington, M. B. Poeran, J. Zubizarreta, N. Memtsoudis, S. G. | British Journal of Anaesthesia | 2018 |
total hip prosthesis |
| Impact of dexmedetomidine infusion during general anaesthesia on incidence of postoperative delirium in elderly patients after major non-cardiac surgery: study protocol of a randomised, double-blinded and placebo-controlled trial. | Wang, B. J. Li, C. J. Hu, J. Li, H. J. Guo, C. Wang, Z. H. Zhang, Q. C. Mu, D. L. Wang, D. X. | BMJ Open | 2018 |
elderly |
| Can education improve clinical practice concerning delirium in older hospitalised patients? Results of a pre-test post-test study on an educational intervention for nursing staff. | van Velthuijsen, E. L. Zwakhalen, S. M. G. Warnier, R. M. J. Ambergen, T. Mulder, W. J. Verhey, F. R. J. Kempen, Gijm | BMC Med Educ | 2018 |
Delirium |
| Withdrawal versus continuation of long-term antipsychotic drug use for behavioural and psychological symptoms in older people with dementia. | Van Leeuwen, E. Petrovic, M. van Driel, M. L. De Sutter, A. I. M. Vander Stichele, R. Declercq, T. Christiaens, T. | Cochrane Database of Systematic Reviews | 2018 |
chlorpromazine |
| Delirium in the Intensive Care Unit: Incidence, risk factors, and impact on outcome. | Tilouche, N. Hassen, M. F. Ali, H. B. S. Jaoued, O. Gharbi, R. El Atrous, S. | Indian Journal of Critical Care Medicine | 2018 |
endotracheal tube |
| Should This Patient Receive Prophylactic Medication to Prevent Delirium?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center. | Tess, A. V. Mattison, M. L. P. Leo, J. R. Reynolds, E. E. | Ann Intern Med | 2018 | |
| Use of the CAM-ICU during daily sedation stops in mechanically ventilated patients as assessed and experienced by intensive care nurses - A mixed-methods study. | Steinseth, E. B. Hoye, S. Hov, R. | Intensive Crit Care Nurs | 2018 |
Assessment |
| Risk factors and outcome of postoperative delirium after transcatheter aortic valve replacement. | Stachon, P. Kaier, K. Zirlik, A. Reinohl, J. Heidt, T. Bothe, W. Hehn, P. Zehender, M. Bode, C. von Zur Muhlen, C. | Clin Res Cardiol | 2018 |
In-hospital mortality |
| Neurological Sequelae and Clinical Outcomes After Lung Transplantation. | Smith, P. J. Stonerock, G. L. Ingle, K. K. Saulino, C. K. Hoffman, B. Wasserman, B. Blumenthal, J. A. Palmer, S. M. Klapper, J. A. Hartwig, M. G. Esposito, V. R. Snyder, L. D. | Transplant Direct | 2018 | |
| Comparison of Ketamine- Versus Nonketamine-Based Sedation on Delirium and Coma in the Intensive Care Unit. | Shurtleff, V. Radosevich, J. J. Patanwala, A. E. | Journal of Intensive Care Medicine | 2018 |
adult |
| Postoperative delirium in elderly patients with critical limb ischemia undergoing major leg amputation: a retrospective study. | Shin, Y. H. Yoon, J. S. Jeon, H. J. Kim, Y. B. Kim, Y. S. Park, J. Y. | Korean J Anesthesiol | 2018 |
Amputation |
| The validity and reliability of the Arabic version of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU): A prospective cohort study | Selim, A. Kandeel, N. Elokl, M. Khater, M. S. Saleh, A. N. Bustami, R. Ely, E. W. | Int J Nurs Stud | 2018 |
Delirium |
| Validation of Caregiver-Centered Delirium Detection Tools: A Systematic Review. | Rosgen, B. Krewulak, K. Demiantschuk, D. Ely, E. W. Davidson, J. E. Stelfox, H. T. Fiest, K. M. | J Am Geriatr Soc | 2018 |
caregiver |
| Study protocol to assess the effectiveness and safety of a flexible family visitation model for delirium prevention in adult intensive care units: a cluster-randomised, crossover trial (The ICU Visits Study). | Rosa, R. G. Falavigna, M. Robinson, C. C. da Silva, D. B. Kochhann, R. de Moura, R. M. Santos, M. M. S. Sganzerla, D. Giordani, N. E. Eugenio, C. Ribeiro, T. Cavalcanti, A. B. Bozza, F. Azevedo, L. C. P. Machado, F. R. Salluh, J. I. F. Pellegrini, J. A. S | BMJ Open | 2018 |
critical care |
| Attention, arousal and other rapid bedside screening instruments for delirium in older patients: a systematic review of test accuracy studies. | Quispel-Aggenbach, D. W. P. Holtman, G. A. Zwartjes, Haht Zuidema, S. U. Luijendijk, H. J. | Age & Ageing | 2018 | |
| Use of haloperidol versus atypical antipsychotics and risk of in-hospital death in patients with acute myocardial infarction: Cohort study | Park, Y. Bateman, B. T. Kim, D. H. Hernandez-Diaz, S. Patorno, E. Glynn, R. J. Mogun, H. Huybrechts, K. F. | BMJ | 2018 |
acetylsalicylic acid |
| Postictal delirium and violent behavior in patients with post-neurosurgical epilepsy. | Oueslati, B. Fekih-Romdhane, F. Ridha, R. | World Neurosurg | 2018 |
epilepsy |
| Factor Analysis of Delirium in Elderly, Using the Korean Version of Delirium Rating Scale-Revised-98. | Noh, G. Kwon, I. Lee, M. Ahn, S. H. Kim, J. L. | Psychiatry Investigation | 2018 |
Aged |
| Flexible Versus Restrictive Visiting Policies in ICUs: A Systematic Review and Meta-Analysis. | Nassar Junior, A. P. Besen, Bamp Robinson, C. C. Falavigna, M. Teixeira, C. Rosa, R. G. | Crit Care Med | 2018 | |
| Effectiveness of non-pharmacological strategies for managing delirium in hospitalized postoperative adults: An umbrella review protocol. | McNeil, J. Denis, A. M. Michel, U. Concert, C. M. | JBI Database of Systematic Reviews and Implementation Reports | 2018 |
adult |
| Genome-wide association identifies a novel locus for delirium risk. | McCoy, T. H. Hart, K. Pellegrini, A. Perlis, R. H. | Neurobiology of Aging | 2018 |
adult |
| Risk factors for postoperative delirium in patients undergoing free flap reconstruction for oral cancer. | Makiguchi, T. Yokoo, S. Kurihara, J. | Int J Oral Maxillofac Surg | 2018 |
delirium |
| Risk factors for mortality in elderly patients with hip fractures: a meta-analysis of 18 studies. | Liu, Y. Wang, Z. Xiao, W. | Aging Clin Exp Res | 2018 |
Elderly |
| Inflammatory markers in postoperative delirium (POD) and cognitive dysfunction (POCD): A meta-analysis of observational studies. | Liu, X. Yu, Y. Zhu, S. | PLoS One | 2018 | |
| Systematic review of prediction models for delirium in the older adult inpatient. | Lindroth, H. Bratzke, L. Purvis, S. Brown, R. Coburn, M. Mrkobrada, M. Chan, M. T. V. Davis, D. H. J. Pandharipande, P. Carlsson, C. M. Sanders, R. D. | BMJ Open | 2018 |
delirium |
| Age is the Most Significantly Associated Risk Factor with the Development of Delirium in Patients Hospitalized for More Than Five Days in Surgical Wards: Retrospective Cohort Study. | Kubota K, Suzuki A, Ohde S, Yamada U, Hosaka T, Okuno F, Fujitani I, Koitabashi A, Shimada G, Kishida A | Annals of surgery | 2017 |
nitrogen |
| Reduced ex vivo release of pro-inflammatory cytokines and elevated plasma interleukin-6 are inflammatory signatures of post-stroke delirium. | Kowalska, K. Klimiec, E. Weglarczyk, K. Pera, J. Slowik, A. Siedlar, M. Dziedzic, T. | J Neuroinflammation | 2018 |
Cytokines |
| Parkinson's disease-related non-motor features as risk factors for post-operative delirium in spinal surgery. | Kim, K. H. Kang, S. Y. Shin, D. A. Yi, S. Ha, Y. Kim, K. N. Sohn, Y. H. Lee, P. H. | PLoS One | 2018 | |
| Relationships between markers of neurologic and endothelial injury during critical illness and long-term cognitive impairment and disability. | Hughes, C. G. Patel, M. B. Brummel, N. E. Thompson, J. L. McNeil, J. B. Pandharipande, P. P. Jackson, J. C. Chandrasekhar, R. Ware, L. B. Ely, E. W. Girard, T. D. | Intensive Care Medicine | 2018 |
NCT00392795 |
| Incidence, Risk Factors, and Sequelae of Post-kidney Transplant Delirium. | Haugen, C. E. Mountford, A. Warsame, F. Berkowitz, R. Bae, S. G. Thomas A Brown, C. H. th Brennan, D. C. Neufeld, K. J. Carlson, M. C. Segev, D. L. McAdams-DeMarco, M. | J Am Soc Nephrol | 2018 |
clinical |
| Evaluation of an Intervention With Nurses for Delirium Detection After Cardiac Surgery. | Fraser, V. Cossette, S. Mailhot, T. Brisebois, A. Dubé, V. | Worldviews on evidence-based nursing | 2018 |
adult |
| Delirium clinical motor subtypes: a narrative review of the literature and insights from neurobiology. | FitzGerald JM | Aging & mental health | 2017 |
Screening and diagnosis |
| Are antipsychotics effective for the prevention of postoperative delirium? | Castro, V. Guinguis, R. Carrasco, M. | Medwave | 2018 | |
| Measuring mobility in older hospital patients with cognitive impairment using the de Morton Mobility Index. | Braun, T. Gruneberg, C. Thiel, C. Schulz, R. J. | BMC Geriatr | 2018 |
Dementia |
| Haloperidol for delirium in critically ill patients – protocol for a systematic review. | Barbateskovic, M. Kraus, S. R. Collet, M. O. Mathiesen, O. Jakobsen, J. C. Perner, A. Wetterslev, J. | Acta Anaesthesiol Scand | 2018 |
haloperidol |
| Dexmedetomidine vs morphine and midazolam in the prevention and treatment of delirium after adult cardiac surgery; a randomized, double-blinded clinical trial. | Azeem, T. M. A. Yosif, N. E. Alansary, A. M. Esmat, I. M. Mohamed, A. K. | Saudi J Anaesth | 2018 |
Dexmedetomidine |
| Psychometric properties of the Arabic version of the confusion assessment method for the intensive care unit (CAM-ICU). | Aljuaid, M. H. Deeb, A. M. Dbsawy, M. Alsayegh, D. Alotaibi, M. Arabi, Y. M. | BMC Psychiatry | 2018 |
Arabic |
| Postoperative delirium, learning, and anesthetic neurotoxicity: Some perspectives and directions. | Mutch, W. A. El-Gabalawy, R. M. Graham, M. R. | Frontiers in Neurology | 2018 |
adult |
| Designing a nurse-delivered delirium bundle: What intensive care unit staff, survivors, and their families think? | Bannon, L. McGaughey, J. Clarke, M. McAuley, D. F. Blackwood, B. | Aust Crit Care | 2018 |
Delirium |
| The 2014 updated version of the Confusion Assessment Method for the Intensive Care Unit compared to the 5th version of the Diagnostic and Statistical Manual of Mental Disorders and other current methods used by intensivists. | Chanques, G. Ely, E. W. Garnier, O. Perrigault, F. Eloi, A. Carr, J. Rowan, C. M. Prades, A. de Jong, A. Moritz-Gasser, S. Molinari, N. Jaber, S. | Ann Intensive Care | 2018 |
Critical care |
| Effect of a 24-h extended visiting policy on delirium in critically ill patients. | Westphal, G. A. Moerschberger, M. S. Vollmann, D. D. Inacio, A. C. Machado, M. C. Sperotto, G. Cavalcanti, A. B. Koenig, A. | Intensive Care Medicine | 2018 | |
| Effect of Sedation Regimen on Weaning from Mechanical Ventilation in the Intensive Care Unit. | Nunes, S. L. Forsberg, S. Blomqvist, H. Berggren, L. Sorberg, M. Sarapohja, T. Wickerts, C. J. | Clin Drug Investig | 2018 | |
| Validation of the korean version of the delirium motor subtype scale. | Kim, H. Lee, M. Kwon, I. S. Kim, J. L. | Psychiatry Investigation | 2018 |
aged |
| e-Screening revolution: A novel approach to developing a delirium screening tool in the intensive care unit. | Eeles, E. Gunn, H. Sutt, A. L. Pinsker, D. Flaws, D. Jarrett, P. Lye, I. Fraser, J. F. | Australasian Journal on Ageing | 2018 |
delirium |
| Sedation Intensity in the First 48 Hours of Mechanical Ventilation and 180-Day Mortality: A Multinational Prospective Longitudinal Cohort Study. | Shehabi, Y. Bellomo, R. Kadiman, S. Ti, L. K. Howe, B. Reade, M. C. Khoo, T. M. Alias, A. Wong, Y. L. Mukhopadhyay, A. McArthur, C. Seppelt, I. Webb, S. A. Green, M. Bailey, M. J. | Crit Care Med | 2018 | |
| Screening for delirium with the Intensive Care Delirium Screening Checklist (ICDSC): a re-evaluation of the threshold for delirium. | Boettger, S. Garcia Nunez, D. Meyer, R. Richter, A. Rudiger, A. Schubert, M. Jenewein, J. | Swiss Medical Weekly | 2018 | |
| Risk Factors of Postoperative Delirium in the Intensive Care Unit After Liver Transplantation. | Lee, H. Oh, S. Y. Yu, J. H. Kim, J. Yoon, S. Ryu, H. G. | World J Surg | 2018 | |
| Risk Factors for Postoperative Delirium After Deep Brain Stimulation Surgery for Parkinson's Disease. | Tanaka, M. Tani, N. Maruo, T. Oshino, S. Hosomi, K. Saitoh, Y. Kishima, H. | World Neurosurg | 2018 |
Deep Brain Stimulation |
| The relationship of delirium and risk factors in cardiology intensive care unit patients with the nursing workload. | Ozturk Birge, A. Beduk, T. | J Clin Nurs | 2018 |
Critical Care |
| Protocol for a single-centre prospective observational study of postoperative delirium following total joint arthroplasties among South East Asians. | Abdullah, H. R. Tan, S. R. Lee, S. J. Bin Abd Razak, H. R. Seet, R. H. Ying, H. Sethi, E. Sim, E. Y. | BMJ Open | 2018 |
*delirium |
| Preoperative statins are associated with a reduced risk of postoperative delirium following vascular surgery. | Lee, D. S. Lee, M. Y. Park, C. M. Kim, D. I. Kim, Y. W. Park, Y. J. | PLoS One | 2018 | |
| Predisposing and precipitating factors for delirium in community-dwelling older adults admitted to hospital with this condition: A prospective case series. | Magny, E. Le Petitcorps, H. Pociumban, M. Bouksani-Kacher, Z. Pautas, É Belmin, J. Bastuji-Garin, S. Lafuente-Lafuente, C. | PLoS One | 2018 |
aged |
| Predicting excess cost for older inpatients with clinical complexity: A retrospective cohort study examining cognition, comorbidities and complications | Bail, K. Draper, B. Berry, H. Karmel, R. Goss, J. | PLoS One | 2018 |
adult |
| Pilot Study of a Two-Step Delirium Detection Protocol Administered By Certified Nursing Assistants, Physicians, and Registered Nurses. | Fick, D. M. Inouye, S. K. McDermott, C. Zhou, W. Ngo, L. Gallagher, J. McDowell, J. Penrod, J. Siuta, J. Covaleski, T. Marcantonio, E. R. | J Gerontol Nurs | 2018 | |
| Perioperative hyperglycaemia and neurocognitive outcome after surgery: a systematic review. | Hermanides, J. Qeva, E. Preckel, B. Bilotta, F. | Minerva Anestesiol | 2018 | |
| Low-dose Nocturnal Dexmedetomidine Prevents ICU Delirium: A Randomized, Placebo-controlled Trial. | Skrobik, Y. Duprey, M. S. Hill, N. S. Devlin, J. W. | Am J Respir Crit Care Med | 2018 |
delirium, sleep, intensive care, dexmedetomidine, randomized controlled trial |
| Low peripheral levels of insulin growth factor-1 are associated with high incidence of delirium among elderly patients: A systematic review and meta-analysis. | Li, D. J. Tseng, P. T. Stubbs, B. Chen, T. Y. Lin, P. Y. Chen, S. L. Thompson, T. Adamis, D. Chu, C. S. | Arch Gerontol Geriatr | 2018 |
Biomarker |
| Is anemia associated with cognitive impairment and delirium among older acute surgical patients? | Myint, P. K. Owen, S. McCarthy, K. Pearce, L. Moug, S. J. Stechman, M. J. Hewitt, J. Carter, B. | Geriatrics & Gerontology International | 2018 |
anemia |
| Intraoperative Sedation With Dexmedetomidine is Superior to Propofol for Elderly Patients Undergoing Hip Arthroplasty: A Prospective Randomized Controlled Study. | Mei, B. Meng, G. Xu, G. Cheng, X. Chen, S. Zhang, Y. Zhang, M. Liu, X. Gu, E. | Clin J Pain | 2018 | |
| Infrared pupillometry helps to detect and predict delirium in the post-anesthesia care unit. | Yang E, Kreuzer M, Hesse S, Davari P, Lee SC, García PS | Journal of clinical monitoring and computing | 2017 |
PLR-200 |
| Influence of Physical Restraint on Delirium of Adult Patients in ICU: A Nested Case-Control Study. | Pan, Y. Jiang, Z. Changrong, Y. Wang, L. Zhang, J. Zhou, J. Tao, M. Quan, M. Wu, Q. | J Clin Nurs | 2018 |
Delirium |
| Incidence of delirium in the Canadian emergency department and its consequences on hospital length of stay: A prospective observational multicentre cohort study. | Émond, M. Boucher, V. Carmichael, P. H. Voyer, P. Pelletier, M. Gouin, É Daoust, R. Berthelot, S. Lamontagne, M. E. Morin, M. Lemire, S. Minh Vu, T. T. Nadeau, A. Rheault, M. Juneau, L. Le Sage, N. Lee, J. | BMJ Open | 2018 |
aged |
| Impact of timing and duration of postoperative delirium: a retrospective observational study | Lee, H. Ju, J. W. Oh, S. Y. Kim, J. Jung, C. W. Ryu, H. G. | Surgery | 2018 | |
| Frequency and risk factors for subsyndromal delirium in an intensive care unit. | Yamada, C. Iwawaki, Y. Harada, K. Fukui, M. Morimoto, M. Yamanaka, R. | Intensive Crit Care Nurs | 2018 |
Delirium |
| Focusing on Inattention: The Diagnostic Accuracy of Brief Measures of Inattention for Detecting Delirium. | Marra, A. Jackson, J. C. Ely, E. W. Graves, A. J. Schnelle, J. F. Dittus, R. S. Wilson, A. Han, J. H. | J Hosp Med | 2018 | |
| Feasibility of Cognitive Training in Critically Ill Patients: A Pilot Study. | Wassenaar, A. Rood, P. Boelen, D. Schoonhoven, L. Pickkers, P. van den Boogaard, M. | Am J Crit Care | 2018 | |
| Evaluation of a sound environment intervention in an ICU: A feasibility study. | Johansson, L. Lindahl, B. Knutsson, S. Ogren, M. Persson Waye, K. Ringdal, M. | Aust Crit Care | 2018 |
Complex intervention |
| Effects of Haloperidol on Delirium in Adult Patients: A Systematic Review and Meta-analysis. | Shen, Y. Z. Peng, K. Zhang, J. Meng, X. W. Ji, F. | Med Princ Pract | 2018 | |
| The effect of the timing and dose of dexmedetomidine on postoperative delirium in elderly patients after laparoscopic major non-cardiac surgery: A double blind randomized controlled study. | Lee, C. Lee, C. H. Lee, G. Lee, J. Hwang, J. | J Clin Anesth | 2018 |
Cytokine |
| Effect of organisational factors on the variation in incidence of delirium in intensive care unit patients: A systematic review and meta-regression analysis. | Rood, P. Huisman-de Waal, G. Vermeulen, H. Schoonhoven, L. Pickkers, P. van den Boogaard, M. | Aust Crit Care | 2018 |
Critical care |
| Effect of Administration of Ramelteon, a Melatonin Receptor Agonist, on the Duration of Stay in the ICU: A Single-Center Randomized Placebo-Controlled Trial. | Nishikimi, M. Numaguchi, A. Takahashi, K. Miyagawa, Y. Matsui, K. Higashi, M. Makishi, G. Matsui, S. Matsuda, N. | Crit Care Med | 2018 | |
| Diagnostic accuracy of delirium assessment methods in critical care patients | Barman, A. Pradhan, D. Bhattacharyya, P. Dey, S. Bhattacharjee, A. Tesia, S. S. Mitra, J. K. | Journal of Critical Care | 2018 |
Acute Physiology and Chronic Health Evaluation II |
| Delirium in ICU Patients Following Cardiac Surgery: An Observational Study. | Simeone, S. Pucciarelli, G. Perrone, M. Rea, T. Gargiulo, G. Guillari, A. Castellano, G. Di Tommaso, L. Niola, M. Iannelli, G. | J Clin Nurs | 2018 |
Icu |
| Clinical phenotypes of delirium during critical illness and severity of subsequent long-term cognitive impairment: a prospective cohort study. | Girard, T. D. Thompson, J. L. Pandharipande, P. P. Brummel, N. E. Jackson, J. C. Patel, M. B. Hughes, C. G. Chandrasekhar, R. Pun, B. T. Boehm, L. M. Elstad, M. R. Goodman, R. B. Bernard, G. R. Dittus, R. S. Ely, E. W. | Lancet Respir Med | 2018 | |
| Postoperative Complications Associated With Spine Surgery in Patients Older Than 90 Years: A Multicenter Retrospective Study. | Kobayashi, K. Imagama, S. Sato, K. Kato, F. Kanemura, T. Yoshihara, H. Sakai, Y. Shinjo, R. Hachiya, Y. Osawa, Y. Matsubara, Y. Ando, K. Nishida, Y. Ishiguro, N. | Global Spine J | 2018 |
complications |
| Do the Phenotypes of Symptom Fluctuation Differ Among Motor Subtypes in Patients With Delirium?. | Kim, S. Y. Kim, J. M. Kim, S. W. Kim, E. S. Kang, H. J. Lee, J. Y. Bae, K. Y. Shin, I. S. Yoon, J. S. | J Pain Symptom Manage | 2018 |
Delirium |
| Delirium and its consequences in the specialized palliative care unit: Validation of the Korean version of Memorial Delirium Assessment Scale. | Kang, B. Kim, Y. J. Suh, S. W. Son, K. L. Ahn, G. S. Park, H. Y. | Psycho-Oncology | 2018 |
adult |
| The Motoric Types of Delirium and Estimated Blood Loss during Perioperative Period in Orthopedic Elderly Patients. | Hong, N. Park, J. Y. | Biomed Res Int | 2018 | |
| CSF sTREM2 in delirium-relation to Alzheimer's disease CSF biomarkers Abeta42, t-tau and p-tau. | Henjum, K. Quist-Paulsen, E. Zetterberg, H. Blennow, K. Nilsson, L. N. G. Watne, L. O. | J Neuroinflammation | 2018 |
Alzheimer’s disease |
| CSF biomarkers in delirium: a systematic review. | Hall RJ, Watne LO, Cunningham E, Zetterberg H, Shenkin SD, Wyller TB, MacLullich AMJ | International journal of geriatric psychiatry | 2017 |
CSF biomarkers |
| Prediction of ICU Delirium: Validation of Current Delirium Predictive Models in Routine Clinical Practice. | Green, C. Bonavia, W. Toh, C. Tiruvoipati, R. | Crit Care Med | 2018 | |
| The Incidence of Recorded Delirium Episodes Before and After Dementia Diagnosis: Differences Between Dementia With Lewy Bodies and Alzheimer's Disease. | FitzGerald, J. M. Perera, G. Chang-Tave, A. Price, A. Rajkumar, A. P. Bhattarai, M. O'Brien, J. T. Ballard, C. Aarsland, D. Stewart, R. Mueller, C. | J Am Med Dir Assoc | 2018 |
Alzheimer’s disease |
| Pain and delirium in people with dementia in the acute general hospital setting. | Feast, A. R. White, N. Lord, K. Kupeli, N. Vickerstaff, V. Sampson, E. L. | Age Ageing | 2018 | |
| Environmental factors and risk of delirium in geriatric patients: an observational study. | Evensen, S. Saltvedt, I. Lydersen, S. Wyller, T. B. Taraldsen, K. Sletvold, O. | BMC Geriatr | 2018 |
Delirium |
| Validity of a screening method for delirium risk in older patients admitted to a general hospital in the Netherlands. | Ettema, R. Heim, N. Hamaker, M. Emmelot-Vonk, M. van der Mast, R. Schuurmans, M. | General Hospital Psychiatry | 2018 |
aged |
| Indwelling urinary catheters, aortic valve treatment and delirium: a prospective cohort study. | Eide, L. S. Ranhoff, A. H. Lauck, S. Fridlund, B. Haaverstad, R. Hufthammer, K. O. Kuiper, K. K. J. Nordrehaug, J. E. Norekval, T. M. | BMJ Open | 2018 |
Savr |
| Diagnostic value of NT-proCNP compared to NSE and S100B in cerebrospinal fluid and plasma of patients with sepsis-associated encephalopathy. | Ehler, J. Saller, T. Wittstock, M. Rommer, P. S. Chappell, D. Zwissler, B. Grossmann, A. Richter, G. Reuter, D. A. Noldge-Schomburg, G. Sauer, M. | Neurosci Lett | 2018 |
Biomarker |
| Exploration of Relationships Between Postoperative Pain and Subsyndromal Delirium in Older Adults. | Denny, D. L. Such, T. L. | Nurs Res | 2018 | |
| Prediction of Incident Delirium Using a Random Forest classifier. | Corradi, J. P. Thompson, S. Mather, J. F. Waszynski, C. M. Dicks, R. S. | J Med Syst | 2018 |
Decision support |
| The hip fracture surgery in elderly patients (HIPELD) study to evaluate xenon anaesthesia for the prevention of postoperative delirium: a multicentre, randomized clinical trial. | Coburn, M. Sanders, R. D. Maze, M. Nguyên-Pascal, M. L. Rex, S. Garrigues, B. Carbonell, J. A. Garcia-Perez, M. L. Stevanovic, A. Kienbaum, P. Neukirchen, M. Schaefer, M. S. Borghi, B. van Oven, H. Tognù, A. Al Tmimi, L. Eyrolle, L. Langeron, O. Capdevi | British Journal of Anaesthesia | 2018 |
C reactive protein |
| Effect of a single pre-operative 125 mg dose of methylprednisolone on postoperative delirium in hip fracture patients; a randomised, double-blind, placebo-controlled trial. | Clemmesen, C. G. Lunn, T. H. Kristensen, M. T. Palm, H. Foss, N. B. | Anaesthesia | 2018 |
delirium |
| Identifying Patterns of Delirium in Hospitalized Patients on Dexamethasone Using a Chart Abstraction Tool. | Chang, J. T. Atayee, R. S. Edmonds, K. P. | Journal of Pain and Palliative Care Pharmacotherapy | 2018 |
dexamethasone |
| Detecting delirium in elderly medical emergency patients: validation and subsequent modification of the German Nursing Delirium Screening Scale. | Brich, J. Baten, V. Wussmann, J. Heupel-Reuter, M. Perlov, E. Kloppel, S. Busch, H. J. | Intern Emerg Med | 2018 |
Delirium |
| Mobilizing older adults: A multi-site, exploratory and observational study on patients enrolled in the Hospital Elder Life Program (HELP). | Babine, R. L. Hyrkas, K. E. McKenzie, C. G. Wierman, H. R. | Geriatr Nurs | 2018 |
Older adults |
| Validation of the Stanford Proxy Test for Delirium (S-PTD) among critical and noncritical patients. | Alosaimi, F. D. Alghamdi, A. Alsuhaibani, R. Alhammad, G. Albatili, A. Albatly, L. Althomali, B. Aljamaan, F. Maldonado, J. R. | J Psychosom Res | 2018 |
Delirium |
| Impact of an Antipsychotic Discontinuation Bundle During Transitions of Care in Critically Ill Patients. | D’Angelo, R. G. Rincavage, M. Tata, A. L. Millstein, L. S. Gulati, M. S. Flurie, R. W. Gonzales, J. P. | J Intensive Care Med | 2019 |
urinary catheter |