What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Pharmacological Management of Sleep-Wake Disturbances in Delirium
- Authors
- Levinsohn, E. A. Radhakrishnan, V. Euting, H. Kaplan, G. B.
- Year
- 2024
- Journal
- J Clin Pharmacol
- Abstract
Delirium is a heterogeneous syndrome primarily characterized by fluctuations in attention and awareness. Sleep-wake disturbances are a common and significant feature of delirium and can manifest as circadian rhythm inversion, sleep fragmentation, and reduced rapid eye movement (REM) and slow-wave sleep. Some literature suggests that the relationship between sleep disruption and delirium is reciprocal wherein the two reinforce one another and may share an underlying etiology. As there are no FDA-approved medications for delirium or delirium-related sleep disturbances, management is primarily focused on addressing underlying medical concerns and promoting physiologic circadian patterns with non-pharmacological behavioral interventions. In practice, however, medications are often used, albeit with limited evidence to support their use. This literature review explores the pharmacology and pharmacokinetics of several medications with literature investigating their use in delirium: melatonin, ramelteon, dual orexin receptor antagonists (DORAs), and dexmedetomidine. Current evidence suggests a possible benefit of ramelteon or melatonin, dexmedetomidine for patients in the ICU setting, and DORAs as therapeutic options for the re-regulation of sleep-wake cycle disruption in delirium. We discuss pertinent pharmacokinetic and pharmacodynamic factors that may influence clinical decision-making regarding these interventions.
- PMID
PMID: 39415561
- Keywords
Dora
delirium
dexmedetomidine
insomnia
melatonin
ramelteon
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Understanding family carer experiences and perceptions of engagement in delirium prevention and care for adults in hospital: Qualitative systematic review | Lee-Steere, K. Mudge, A. Liddle, J. Bennett, S. | J Clin Nurs | 2024 |
Adult |
| The use of the DOS and Delirium Prevalence: a quantitative longitudinal study at a Swiss-German central hospital | Lauffer-Vogt, S. U. Hediger, H. Lauener, S. K. Schubert, M. | Pflege | 2024 |
Female |
| Melatonin does not reduce delirium severity in hospitalized older adults: Results of a randomized placebo-controlled trial | Lange, P. W. Turbić, A. Soh, C. H. Clayton-Chubb, D. Lim, W. K. Conyers, R. Watson, R. Maier, A. B. | J Am Geriatr Soc | 2024 |
aged neurocognitive disorders |
| Immunological Analysis of Postoperative Delirium after Thoracic Aortic Surgery | Ko, H. Kayumov, M. Lee, K. S. Oh, S. G. Na, K. J. Jeong, I. S. | J Chest Surg | 2024 |
Aorta |
| Risk Factors for Postoperative Cognitive Decline After Orthopedic Surgery in Elderly Chinese Patients: A Retrospective Cohort Study | Li, X. Lai, H. Wang, P. Feng, S. Feng, X. Kong, C. Wu, D. Yin, C. Shen, J. Yan, S. Han, R. Liu, J. Ren, X. Li, Y. Tang, L. Xue, D. Zhao, Y. Huang, H. Li, X. Zhang, Y. Wang, X. Wang, C. Jin, P. Lu, S. Wang, T. Zhao, G. Wang, C. | Clin Interv Aging | 2024 |
Aged |
| Clinical Impact of the Implementation Strategies Used to Apply the 2013 Pain, Agitation/Sedation, Delirium or 2018 Pain, Agitation/Sedation, Delirium, Immobility, Sleep Disruption Guideline Recommendations: A Systematic Review and Meta-Analysis | Hume, N. E. Zerfas, I. Wong, A. Klein-Fedyshin, M. Smithburger, P. L. Buckley, M. S. Devlin, J. W. Kane-Gill, S. L. | Crit Care Med | 2024 |
Adult |
| Delirium and incident dementia in hospital patients in New South Wales, Australia: retrospective cohort study | Gordon, E. H. Ward, D. D. Xiong, H. Berkovsky, S. Hubbard, R. E. | Bmj | 2024 |
Male |
| Effect of subanesthetic dose of esketamine on postoperative pain in elderly patients undergoing laparoscopic gastrointestinal tumor Surgery:A prospective, double-blind, randomized controlled trial | Jing, Z. Han, Y. Li, Y. Zeng, R. Wu, J. Wang, Y. Jiang, P. | Heliyon | 2024 |
Analgesia |
| Predictive Ability of Amplitude Integrated Electroencephalography for Adverse Outcomes in Neonates with Sepsis-Associated Encephalopathy: A Cohort Study | Jain, P. Saini, S. S. Sahu, J. K. Madaan, P. Sundaram, V. Dutta, S. | Indian J Pediatr | 2024 |
Cerebral function monitor |
| Perioperative knowledge, self-efficacy and clinical practices related to postoperative delirium care in older people across geographical regions in Australia | Igwe, E. O. Nealon, J. O'Shaughnessy, P. Ormonde, C. Traynor, V. | Aust J Rural Health | 2024 |
Australia |
| A survey of non-consultant hospital doctors' perspectives, knowledge, and practices toward delirium in a large Irish hospital | Hassabo, M. Mc Cluskey, P. Browne, J. Ntlholang, O. | Ir J Med Sci | 2024 |
4at |
| Dynamic delirium - Nursing intervention to reduce delirium in patients critically Ill, a randomized control trial | Gómez Tovar, L. O. Henao Castaño, A. M. | Intensive Crit Care Nurs | 2024 |
Clinical Trial |
| Delirium is more common and associated with worse outcomes in Parkinson's disease compared to older adult controls: results of two prospective longitudinal cohort studies | Gerakios, F. Yarnall, A. J. Bate, G. Wright, L. Davis, D. Stephan, B. C. M. Robinson, L. Brayne, C. Stebbins, G. Taylor, J. P. Burn, D. J. Allan, L. M. Richardson, S. J. Lawson, R. A. | Age Ageing | 2024 |
Humans |
| Effectiveness of remimazolam in preventing postoperative delirium in elderly patients with proximal femoral fractures | Fujimoto, D. Obata, N. Mizobuchi, S. | J Anesth | 2024 |
Elderly |
| Association between body mass index and delirium incidence in critically ill patients: a retrospective cohort study based on the MIMIC-IV Database | Fu, J. Zhang, X. Zhang, G. Wei, C. Fu, Q. Gui, X. Ji, Y. Chen, S. | BMJ Open | 2024 |
Humans |
| Structural disconnectivity in postoperative delirium: A perioperative two-center cohort study in older patients | Fislage, M. Winzeck, S. Woodrow, R. Lammers-Lietz, F. Stamatakis, E. A. Correia, M. M. Preller, J. Feinkohl, I. Hendrikse, J. Pischon, T. Spies, C. D. Slooter, A. J. C. Winterer, G. Menon, D. K. Zacharias, N. | Alzheimers Dement | 2024 |
brain health |
| Effects of short-term preoperative intranasal dexmedetomidine plus conventional treatment on delirium following cardiac surgery in patients with sleep disorders | Fang, J. Yang, J. Zhai, M. Zhang, Q. Zhang, M. Xie, Y. | Perioper Med (Lond) | 2024 |
Cognitive function |
| The predictive value of confusion assessment method-intensive care unit and intensive care delirium screening checklist for delirium in critically ill patients in the intensive care unit: A systematic review and meta-analysis | Diao, Y. Yu, X. Zhang, Q. Chen, X. | Nurs Crit Care | 2024 |
Cam‐icu |
| Factors associated with disagreement between clinician app-based ultra-brief Confusion Assessment Method and reference standard delirium assessments | Dhliwayo, R. Trivedi, S. Ngo, L. Fick, D. M. Inouye, S. K. Boltz, M. Leslie, D. Husser, E. Shrestha, P. Marcantonio, E. R. | J Am Geriatr Soc | 2024 |
Humans |
| Cognitive disorders in advanced Parkinson's disease: challenges in the diagnosis of delirium | Daniels, C. Rodríguez-Antigüedad, J. Jentschke, E. Kulisevsky, J. Volkmann, J. | Neurol Res Pract | 2024 |
Cognition |
| Assessment and management of delirium in a tertiary hospital-Improvements in cognitive screening and use of non-pharmacological strategies with a multidisciplinary approach | Clarke, E. Newman, E. Dravid, M. Ricciardello, M. Jones, E. Caudle, K. Kilshaw, L. Hilmi, S. Flicker, L. | Australas J Ageing | 2024 |
Humans |
| Assessment of level of knowledge, attitude, and associated factors toward delirium among health professionals working in intensive care unit multicenter, cross-sectional study, Amhara region comprehensive specialized hospitals, Northwest Ethiopia, 2023 | Ayanaw Eyayu, R. Gudayu Zeleke, T. Chekol, W. B. Yaregal Melesse, D. Enyew Ashagrie, H. | Front Public Health | 2024 |
Humans |
| The evaluation of frequency and predictors of delirium and its short-term and long-term outcomes in hospitalized older adults' | Ajmera, Y. Paul, K. Khan, M. A. Kumari, B. Kumar, N. Chatterjee, P. Dey, A. B. Chakrawarty, A. | Asian J Psychiatr | 2024 |
Humans |
| The impact of ketamine on outcomes in critically ill patients: a systematic review with meta-analysis and trial sequential analysis of randomized controlled trials | Abdildin, Y. Tapinova, K. Nemerenova, A. Viderman, D. | Acute Crit Care | 2024 |
critical care |
| Spanish transcultural adaptation of the 4AT score for the evaluation of delirium in the emergency department: a prospective diagnostic test accuracy study | Morales-Puerto, M. Ruiz-Díaz, M. García-Mayor, S. León-Campos, Á Morales-Asencio, J. M. Canca-Sánchez, J. C. Gavira-Guerra, S. Toledo-Fernandez, C. Aranda-Gallardo, M. | BMC Nurs | 2024 |
4at |
| Face and content validity of a mobile delirium screening tool adapted for use in the medical setting (eDIS-MED): Welcome to the machine | Eeles, E. Tronstad, O. Teodorczuk, A. Flaws, D. Fraser, J. F. Dissanayaka, N. | Australas J Ageing | 2924 |
computerized adaptive testing |
| Social determinants of health and incident postoperative delirium: Exploring key relationships in the SAGES study | Arias, F. Dufour, A. B. Jones, R. N. Alegria, M. Fong, T. G. Inouye, S. K. | J Am Geriatr Soc | 2024 |
Humans |
| Combining biomarkers of BNIP3 L, S100B, NSE and accessible measures to prediction sepsis-associated encephalopathy: a prospective observational study | Zhang, N. Xie, K. Yang, F. Wang, Y. Yang, X. Zhao, L. | Curr Med Res Opin | 2024 |
Bnip3 l |
| Association between preoperative albumin levels and postoperative delirium in geriatric hip fracture patients | Wang, W. Yao, W. Tang, W. Li, Y. Lv, Q. Ding, W. | Front Med (Lausanne) | 2024 |
Pod |
| Antipsychotic Use for ICU Delirium and Associated Inflammatory Markers | Torbic, H. Chen, A. Lumpkin, M. Yerke, J. Mehkri, O. Abraham, S. Wang, X. Duggal, A. Scheraga, R. G. | J Intensive Care Med | 2024 |
Adult |
| Delirium is frequently underdiagnosed among older hospitalised patients despite available information in hospital medical records | Titlestad, I. Haugarvoll, K. Solvang, S. H. Norekvål, T. M. Skogseth, R. E. Andreassen, O. A. Årsland, D. Neerland, B. E. Nordrehaug, J. E. Tell, G. S. Giil, L. M. | Age Ageing | 2024 |
Humans |
| Factors associated with delirium in a real-world acute-care setting: analysis considering the interdependence of clinical variables with the frailty syndrome | Ticinesi, A. Parise, A. Delmonte, D. Coppi, C. Prati, B. Cerundolo, N. Guerra, A. Nouvenne, A. Meschi, T. | Eur Geriatr Med | 2024 |
Acute cerebral dysfunction |
| Increased IgA-mediated responses to the gut paracellular pathway and blood-brain barrier proteins predict delirium due to hip fracture in older adults | Thisayakorn, P. Thipakorn, Y. Tantavisut, S. Sirivichayakul, S. Vojdani, A. Maes, M. | Front Neurol | 2024 |
bacterial translocation |
| Association of peripheral B cells and delirium: combined single-cell sequencing and Mendelian randomization analysis | Tan, S. Pan, S. Wei, L. Chen, W. Pan, B. Kong, G. Chen, J. Xie, Y. | Front Neurol | 2024 |
B cell |
| Clinical Outcomes after Multivalve Surgery in Octogenarians: Evaluating the Need for a Paradigm Shift | Taghizadeh-Waghefi, A. Petrov, A. Arzt, S. Alexiou, K. Tugtekin, S. M. Matschke, K. Kappert, U. Wilbring, M. | J Clin Med | 2024 |
multivalve disease |
| Evaluating early lymphocyte-to-monocyte ratio as a predictive biomarker for delirium in older adult patients with sepsis: insights from a retrospective cohort analysis | Shi, X. Yang, L. Bai, W. Jing, L. Qin, L. | Front Med (Lausanne) | 2024 |
Mimic-iv |
| The Association of Preoperative Diabetes With Postoperative Delirium in Older Patients Undergoing Major Orthopedic Surgery: A Prospective Matched Cohort Study | Shang, Z. Jiang, Y. Fang, P. Zhu, W. Guo, J. Li, L. Liang, Y. Zhang, S. Ma, S. Mei, B. Fan, Y. Xie, Z. Shen, Q. Liu, X. | Anesth Analg | 2024 |
Postoperative delirium diabetes orthopedic surgery elective surgery 3D-CAM delirium severity
|
| The role of neurohospitalism in a specialized cardiovascular hospital | Serôdio, M. Magriço, M. Sobral-Pinho, A. Ventura, R. Serrazina, F. Cabral, G. Meira, B. Fernandes, M. Salavisa, M. Saraiva, M. Marto, J. P. Sá, F. Calado, S. Baptista, M. V. | Eur Neurol | 2024 |
Cardiovascular neurology delirium altered mental status AIS
|
| Bringing Delirium to Light: Impact of CAM-ICU Tool to Improve Care Coordination | Savino, T. Vergara, F. H. Ramos, M. D. Warzecha, D. | Prof Case Manag | 2024 |
Delirium CCU Early assessment CAM-ICU Length of Stay Case Management |
| Delirium and Its Associations with Critical Care Utilizations and Outcomes at the Time of Hospital Discharge in Patients with Acute Brain Injury | Raquer, A. P. Fong, C. T. Walters, A. M. Souter, M. J. Lele, A. V. | Medicina (Kaunas) | 2024 |
Humans |
| Data-derived subtypes of delirium during critical illness | Potter, K. M. Kennedy, J. N. Onyemekwu, C. Prendergast, N. T. Pandharipande, P. P. Ely, E. W. Seymour, C. Girard, T. D. | EBioMedicine | 2024 |
Adult |
| Infection, delirium, and risk of dementia in patients with and without white matter disease on previous brain imaging: a population-based study | Pendlebury, S. T. Luengo-Fernandez, R. Seeley, A. Downer, M. B. McColl, A. Rothwell, P. M. | Lancet Healthy Longev | 2024 |
United States |
| A novel risk assessment tool for postoperative delirium in vascular surgery: The stress model (Siena posTopeRative dElirium in vaScular Surgery) | Pasqui, E. de Donato, G. Brancaccio, B. Casilli, G. Ferrante, G. Palasciano, G. | Vascular | 2024 |
Vascular surgery |
| The Delphi Delirium Management Algorithms. A practical tool for clinicians, the result of a modified Delphi expert consensus approach | Ottens, T. H. Hermes, C. Page, V. Oldham, M. Arora, R. Bienvenu, O. J., 3rd van den Boogaard, M. Caplan, G. Devlin, J. W. Friedrich, M. E. van Gool, W. A. Hanison, J. Hansen, H. C. Inouye, S. K. Kamholz, B. Kotfis, K. Maas, M. B. MacLullich, A. M. J. Marc | Delirium (Bielef) | 2024 |
Clinical practice algorithm |
| Identification of early delirium and its outcomes after cardiopulmonary bypass among adult patients with cardiovascular disease: a prospective observational study | Othman, S. M. A. Xu, Q. Zhao, K. Kafi, L. Aziz, M. A. A. | Indian J Thorac Cardiovasc Surg | 2024 |
Bypass machine |
| Association between Preoperative Glucose Dysregulation and Delirium after Non-Cardiac Surgery | Oh, A. R. Lee, D. Y. Lee, S. Lee, J. H. Yang, K. Choi, B. Park, J. | J Clin Med | 2024 |
delirium |
| Epidural vs. systemic analgesia in the Intensive Care Unit: retrospective study of patient outcomes | Naser, A. Meyer, A. Ifrach, N. Dichtwald, S. | Minerva Anestesiol | 2024 |
Humans |
| Whole blood thiamine, intravenous thiamine supplementation and delirium occurrence in the intensive care unit: retrospective cohort analyses | Mumin, M. A. McKenzie, C. A. Page, V. J. Hadfield, D. Aitken, L. M. Hanks, F. Cunningham, E. Blackwood, B. Van Dellen, E. Slooter, A. J. C. Grocott, M. P. W. McAuley, D. F. Spronk, P. E. | Int J Clin Pharm | 2024 |
Critical care |
| Intraoperative Blood Pressure Management and Its Effects on Postoperative Delirium After Cardiac Surgery: A Single-Center Retrospective Cohort Study | Mohr, N. L. Krannich, A. Jung, H. Hulde, N. von Dossow, V. | J Cardiothorac Vasc Anesth | 2024 |
Ioh |
| Implementing pain, agitation, delirium, and sleep deprivation protocol in critically ill patients: A pilot study on pharmacological interventions | Luetrakool, P. Taesotikul, S. Susantitapong, K. Suthisisang, C. Morakul, S. Sutherasan, Y. Tangsujaritvijit, V. Dilokpattanamongkol, P. | Clin Transl Sci | 2024 |
Humans |
| An exploratory research report on brain mineralization in postoperative delirium and cognitive decline | Lammers-Lietz, F. Borchers, F. Feinkohl, I. Hetzer, S. Kanar, C. Konietschke, F. Lachmann, G. Chien, C. Spies, C. Winterer, G. Zaborszky, L. Zacharias, N. Paul, F. | Eur J Neurosci | 2024 |
anaesthesia |
| Delirium Severity and Physical Function in Hospitalized Persons Living With Dementia: Moderation by Age, Sex, and Race | Kuzmik, A. Boltz, M. Resnick, B. McPherson, R. Rodriguez, M. Drazich, B. F. Galik, E. | Alzheimer Dis Assoc Disord | 2024 |
Male |
| Effectiveness of antipsychotics for managing agitated delirium in patients with advanced cancer: a secondary analysis of a multicenter prospective observational study in Japan (Phase-R) | Kurisu, K. Inada, S. Maeda, I. Nobata, H. Ogawa, A. Iwase, S. Uchida, M. Akechi, T. Amano, K. Nakajima, N. Morita, T. Sumitani, M. Yoshiuchi, K. | Support Care Cancer | 2024 |
Humans |
| The spectrum of psychological disorders in family members of patients suffering from delirium associated with critical illness: a prospective, observational study | Kotfis, K. Maj, P. Szylińska, A. Pankowiak, M. Reszka, E. Ely, E. W. Marra, A. | Sci Rep | 2024 |
Adult |
| Impact of Prefracture Cognitive Impairment and Postoperative Delirium on Recovery After Hip Fracture Surgery | Kamimura, T. Kobayashi, Y. Tamaki, S. Koinuma, M. | J Am Med Dir Assoc | 2024 |
Cognitive impairment |
| Development of a Prediction Model for Delirium in Hospitalized Patients with Advanced Cancer | Jung, E. H. Yoo, S. H. Lee, S. W. Kang, B. Kim, Y. J. | Cancer Res Treat | 2024 |
Delirium |
| Nurses' Knowledge and Subjective Strain in Delirium Care: Impact of a Web-based Instructional Module on Nurses Competence | Jose, S. Cyriac, M. C. Dhandapani, M. | Indian J Crit Care Med | 2024 |
Delirium |
| Difficulties faced by intensive care nurses in caring for patients with delirium: A cross-sectional, multicentre study | Jiang, T. Tung, T. H. Wang, Y. Zheng, X. T. Jia, L. Zhang, W. | Aust Crit Care | 2024 |
Cross-sectional study |
| Short-term outcomes of prehospital opioid pain management for older adults with fall-related injury | Jarman, M. P. Jin, G. Chen, A. Losina, E. Weissman, J. S. Berry, S. D. Salim, A. | J Am Geriatr Soc | 2024 |
emergency medical services |
| Concomitant use of hydroxyzine and haloperidol did not worsen delirium in patients with cancer: A multicenter, retrospective, observational study | Hirayama, T. Igarashi, E. Wada, S. Sadahiro, R. Oshikiri, H. Suzuka, M. Sato, Y. Utsumi, Y. Sakuma, A. Nakahara, R. Imai, T. Tomita, H. Matsuoka, H. | Palliat Support Care | 2024 |
Delirium |
| Valve unit instead of intensive or intermediate care unit admission following transcatheter edge-to-edge mitral valve repair is safe and reduces postprocedural complications | Gröger, M. Felbel, D. Paukovitsch, M. Schneider, L. M. Markovic, S. Rottbauer, W. Keßler, M. | Clin Res Cardiol | 2024 |
Intensive care |
| Delirium in acute stroke is associated with increased cognitive and psychiatric symptoms over time: The Nor-COAST study | Gjestad, E. Nerdal, V. Saltvedt, I. Lydersen, S. Kliem, E. Ryum, T. Grambaite, R. | J Stroke Cerebrovasc Dis | 2024 |
cerebrovascular disease |
| Delirium following traumatic brain injury in adolescents: Symptomatology and prediction of ability to return to school or employment 1-year post-injury | Garofano, J. S. Nakase-Richardson, R. Barnett, S. D. Yablon, S. A. Evans, C. Zaim, N. | Pm r | 2024 |
Humans |
| Developing a set of emergency department performance measures to evaluate delirium care quality for older adults: a modified e-Delphi study | Filiatreault, S. Kreindler, S. A. Grimshaw, J. M. Chochinov, A. Doupe, M. B. | BMC Emerg Med | 2024 |
Humans |
| Delirium is associated with low levels of upright activity in geriatric inpatients-results from a prospective observational study | Evensen, S. Taraldsen, K. Aam, S. Morandi, A. | Aging Clin Exp Res | 2024 |
Humans |
| Improving Healthcare Quality and Clinical Outcomes for Persons with Dementia in the Sub-Acute Hospital Through Person-Centered Care Practice | Chenoweth, L. Burley, C. Cook, J. Cheah, S. L. Reyes, P. Maiden, G. McGuire, J. McCade, D. Brodaty, H. Sukhapure, M. Harrison, F. Williams, A. | J Alzheimers Dis | 2024 |
Alzheimer’s disease |
| Preoperative geriatric nutritional risk index is useful factor for predicting postoperative delirium among elderly patients with degenerative lumbar diseases | Chen, Q. Zhu, C. Ai, Y. Wang, J. Ding, H. Luo, D. Li, Z. Song, Y. Feng, G. Liu, L. | Eur Spine J | 2024 |
Elderly population |
| Association between perioperative self-reported sleep disturbances and delirium risk in elderly patients following total joint arthroplasty: a cohort study | Chen, H. Fang, Z. Wu, Y. Y. Zhao, C. H. Wang, Y. J. Zhu, X. H. Cheng, X. Q. | J Sleep Res | 2024 |
postoperative delirium |
| A Prospective Observational Cohort Study of Language Preference and Preoperative Cognitive Screening in Older Adults: Do Language Disparities Exist in Cognitive Screening and Does the Association Between Test Results and Postoperative Delirium Differ Base | Canales, C. Ramirez, C. M. Yang, S. C. Feinberg, S. A. Grogan, T. R. Whittington, R. A. Sarkisian, C. Cannesson, M. | Anesth Analg | 2024 |
Postoperative Delirium Language other than English preference patients Language disparities Cognitive Screening
|
| Causal relationship between dementia and delirium: Insights from a bidirectional two-sample Mendelian randomization analysis | Cai, Y. Wang, J. Wang, X. Yuan, Q. Xu, Y. Xu, P. | J Affect Disord | 2024 |
Aged |
| Cognitive reserve and the risk of postoperative neurocognitive disorders in older age | Borchers, F. Rumpel, M. Laubrock, J. Spies, C. Kozma, P. Slooter, A. van Montfort, S. J. T. Piper, S. K. Wiebach, J. Winterer, G. Pischon, T. Feinkohl, I. | Front Aging Neurosci | 2023 |
cognitive reserve |
| Gaps in cognitive care among older patients undergoing spine surgery | Barreto Chang, O. L. Pawar, N. Whitlock, E. L. Miller, B. Possin, K. L. | J Am Geriatr Soc | 2024 |
anesthesia |
| Screening and differential diagnosis of delirium in neurointensive stroke patients | Bakošová, L. Kec, D. Škorňa, M. Jura, R. Kundrata, Z. Košťálová, M. Bednařík, J. | Heliyon | 2024 |
Aphasia |
| Validation of PRE-DELIRIC and E-PRE-DELIRIC in a Danish population of intensive care unit patients-A prospective observational multicenter study | Anton Joseph, N. Poulsen, L. M. Maagaard, M. Tholander, S. Pedersen, H. B. S. Georgi-Jensen, C. Mathiesen, O. Andersen-Ranberg, N. C. | Acta Anaesthesiol Scand | 2024 |
Adult |
| The Validity and Applicability of the Revised Delirium Rating Scale (DRS-R98) for Delirium Severity Assessment in a Critical Care Setting | Almuhairi, E. S. Badejo, M. Peer, A. Pitkanen, M. McKenzie, C. A. | J Intensive Care Med | 2024 |
Adult |
| Evaluation of the Efficacy and Safety of Quetiapine in the Treatment of Delirium in Adult ICU Patients: A Retrospective Comparative Study | Alghadeer, S. Almesned, R. S. Alshehri, E. A. Alwhaibi, A. | J Clin Med | 2024 |
Icu |
| Prolonged delirium during hospitalization is associated with worse long-term and short-term outcomes in patients with acute heart failure | Aikawa, Y. Ogata, S. Honda, S. Nagai, T. Murata, S. Morii, I. Anzai, T. Nishimura, K. Noguchi, T. | Int J Cardiol | 2024 |
Humans |
| Safety Analysis of Bapineuzumab in the Treatment of Mild to Moderate Alzheimer's Disease: A Systematic Review and Meta-Analysis | Gao, Y. Guo, J. Zhang, F. Li, Y. | Comb Chem High Throughput Screen | 2024 |
Humans |
| Biomarkers of neurodegeneration and neural injury as potential predictors for delirium | Fong, T. G. Vasunilashorn, S. M. Kivisäkk, P. Metzger, E. D. Schmitt, E. M. Marcantonio, E. R. Jones, R. N. Shanes, H. T. Arnold, S. E. Inouye, S. K. Ngo, L. H. | Int J Geriatr Psychiatry | 2024 |
Humans |
| Effectiveness and safety of second-generation antipsychotics for psychiatric disorders apart from schizophrenia: A systematic review and meta-analysis | Feng, X. Z. Li, Z. Li, Z. Y. Wang, K. Tan, X. Zhao, Y. Y. Mi, W. F. Zhu, W. L. Bao, Y. P. Lu, L. Li, S. X. | Psychiatry Res | 2024 |
Humans |
| Prevalence of Delirium After Abdominal Surgery and Association With Ketamine: A Retrospective, Propensity-Matched Cohort Study | Faisal, H. Qamar, F. Hsu, E. S. Xu, J. Lai, E. C. Wong, S. T. Masud, F. N. | Crit Care Explor | 2024 |
critical care |
| CRP/albumin, Glasgow prognostic score, and prognostic nutritional index as a predictor of mortality among delirium patients | Doğan, R. B. Yavuz, B. G. Satilmis, D. Afacan, M. A. Colak, S. | Ir J Med Sci | 2024 |
Humans |
| DeltaScan for the Assessment of Acute Encephalopathy and Delirium in ICU and non-ICU Patients, a Prospective Cross-Sectional Multicenter Validation Study | Ditzel, F. L. Hut, S. C. A. van den Boogaard, M. Boonstra, M. Leijten, F. S. S. Wils, E. J. van Nesselrooij, T. Kromkamp, M. Rood, P. J. T. Röder, C. Bouvy, P. F. Coesmans, M. Osse, R. J. Pop-Purceleanu, M. van Dellen, E. Krulder, J. W. M. Milisen, K. Fa | Am J Geriatr Psychiatry | 2023 |
Acute encephalopathy |
| Development of a complex intervention to prevent delirium in older hospitalized patients by optimizing discharge and transfer processes and involving caregivers: A multi-method study | Denninger, N. E. Brefka, S. Skudlik, S. Leinert, C. Mross, T. Meyer, G. Sulmann, D. Dallmeier, D. Denkinger, M. Müller, M. | Int J Nurs Stud | 2024 |
Humans to influence the work reported in this paper. |
| Performance and validation of two ICU delirium assessment and severity tools; a prospective observational study | den Boogaard, M. V. Leenders, M. Pop-Purceleanu, M. Tilburgs, B. | Intensive Crit Care Nurs | 2024 |
Assessment |
| "Beyond Feasibility": A Qualitative Study of Patients, Their Whānau (Family) and Staff Perspectives and Experiences of a Non- Pharmacological Delirium-Prevention Intervention in Two Aotearoa/New Zealand Hospices | Davies, C. Basire, K. Jones, V. Gillmore, D. Hosie, A. Gourley, A. Collier, A. | J Pain Symptom Manage | 2024 |
Hospice |
| Does ICU admission dysphagia independently contribute to delirium risk in ischemic stroke patients? Results from a cohort study | Cheng, H. Song, S. Tang, Y. Yuan, S. Huang, X. Ling, Y. Wang, Z. Tian, X. Lyu, J. | BMC Psychiatry | 2024 |
Adult |
| Development and validation of a delirium care critical-thinking scale for intensive care unit nurses: A mixed-method study | Chang, Y. L. Hsieh, M. J. Pan, C. I. Shang, S. T. Tsai, Y. F. | J Clin Nurs | 2024 |
Delphi method |
| Mapping the trajectory of acute mild-stroke cognitive recovery using serial computerised cognitive assessment | Campbell, A. Gustafsson, L. Grimley, R. Gullo, H. Rosbergen, I. Summers, M. | Brain Impair | 2023 |
Humans, Aged, Brain Ischemia, Stroke/complications |
| Risk factors for postoperative delirium in orthopaedic hip surgery patients: a database review | Callan, K. T. Donnelly, M. Lung, B. McLellan, M. DiGiovanni, R. McMaster, W. Yang, S. Stitzlein, R. | BMC Musculoskelet Disord | 2024 |
Humans, Emergence Delirium/complications, Orthopedics, Proximal Femoral Fractures, Postoperative Complications/epidemiology/etiology, Risk Factors, Arthroplasty, Replacement, Hip/adverse effects, Osteoarthritis/complications, Retrospective Studies, Delirium, Hip fracture, Osteoarthritis, Total hip arthroplasty |
| Association of perioperative plasma concentration of neurofilament light with delirium after cardiac surgery: a nested observational study | Brown, C. H. Kim, A. S. Yanek, L. Lewis, A. Mandal, K. Le, L. Tian, J. Neufeld, K. J. Hogue, C. Moghekar, A. | Br J Anaesth | 2024 |
Humans |
| Advancing specificity in delirium: The delirium subtyping initiative | Bowman, E. M. L. Brummel, N. E. Caplan, G. A. Cunningham, C. Evered, L. A. Fiest, K. M. Girard, T. D. Jackson, T. A. LaHue, S. C. Lindroth, H. L. Maclullich, A. M. J. McAuley, D. F. Oh, E. S. Oldham, M. A. Page, V. J. Pandharipande, P. P. Potter, K. M. Si | Alzheimers Dement | 2024 |
Humans |
| Cognitive impairment in critically ill patients and former critically ill patients: A concept analysis | Bødker Hanifa, A. L. Svenningsen, H. Møller, A. N. Dreyer, P. Holm, A. | Aust Crit Care | 2024 |
Humans, Critical Illness/rehabilitation, Quality of Life, Cognitive Dysfunction |
| Effects of structured protocolized physical therapy on the duration of mechanical ventilation in patients with prolonged weaning | Bickenbach, J. Fritsch, S. Cosler, S. Simon, Y. Dreher, M. Theisen, S. Kao, J. Hildebrand, F. Marx, G. Simon, T. P. | J Crit Care | 2024 |
Humans, Respiration, Artificial/adverse effects, Ventilator Weaning/methods, Hand Strength, Critical Illness/therapy, Time Factors, Intensive Care Units, Physical Therapy Modalities, ICU-acquired weakness, Mechanical ventilation, Physiotherapy, Prolonged weaning |
| The Utilization of Preoperative Steroids Safely Decreases the Risk of Postoperative Delirium in Geriatric Patients after Hip Fracture Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials | Baumann, A. N. Talaski, G. M. Uhler, M. A. Anastasio, A. T. Walley, K. C. Pean, C. A. Tampi, R. R. Farivar, M. | J Orthop Trauma | 2024 |
geriatric, postoperative delirium, hip fracture, steroids |
| Nomogram to predict the incidence of delirium in elderly patients with non-severe SARS-CoV-2 infection | An, G. Mi, Z. Hong, D. Ou, D. Cao, X. Liu, Q. Xiong, L. Li, C. | Front Psychiatry | 2023 |
Omicron |
| Practical Application of a Battery of Brief Tools to Evaluate Geriatric Medical Inpatients for the Three Ds | Alviz Núñez, M. Villa García, M. M. Gonzalez, M. C. Urrea, M. B. Velásquez-Tirado, J. D. Ocampo, M. V. Trzepacz, P. T. Franco, J. G. | J Neuropsychiatry Clin Neurosci | 2024 |
Humans, Aged, Delirium/diagnosis/epidemiology/psychology, Dementia/diagnosis/epidemiology/psychology, Inpatients, Cross-Sectional Studies, Ddt, Comorbidity, Delirium, Dementia, Depression, Geriatric Neuropsychiatry, The 3 Ds |
| Preoperative electroencephalographic alpha-power changes with eyes opening are associated with postoperative attention impairment and inattention-related delirium severity | Acker, L. Wong, M. K. Wright, M. C. Reese, M. Giattino, C. M. Roberts, K. C. Au, S. Colon-Emeric, C. Lipsitz, L. A. Devinney, M. J. Browndyke, J. Eleswarpu, S. Moretti, E. Whitson, H. E. Berger, M. Woldorff, M. G. | Br J Anaesth | 2024 |
Humans, Electroencephalography, Cognitive Dysfunction, Cognition, Emergence, Delirium/diagnosis, Attention, Postoperative Complications/diagnosis, alpha attenuation, delirium, eyes opening, postoperative delirium |
| Ketofol versus Dexmedetomidine for preventing postoperative delirium in elderly patients undergoing intestinal obstruction surgeries: a randomized controlled study | Abd Ellatif, S. E. Mowafy, S. M. S. Shahin, M. A. | BMC Anesthesiol | 2024 |
Humans, Aged, Emergence Delirium/epidemiology/prevention & control, Dexmedetomidine/therapeutic use, Prospective Studies, Propofol, Postoperative Complications/epidemiology/prevention & control/chemically induced, Double-Blind Method, Dexmedetomidine, Elderly patients, Intestinal obstruction surgeries, Ketofol, Postoperative delirium |
| Delirium is associated with loss of feedback cortical connectivity | Gjini, K. Casey, C. Kunkel, D. Her, M. Banks, M. I. Pearce, R. A. Lennertz, R. Sanders, R. D. | Alzheimers Dement | 2024 |
Humans, Feedback, Evoked Potentials, Auditory/physiology, Electroencephalography, Inflammation, Delirium |