Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Clinical Impact of the Implementation Strategies Used to Apply the 2013 Pain, Agitation/Sedation, Delirium or 2018 Pain, Agitation/Sedation, Delirium, Immobility, Sleep Disruption Guideline Recommendations: A Systematic Review and Meta-Analysis
Authors
Hume, N. E. Zerfas, I. Wong, A. Klein-Fedyshin, M. Smithburger, P. L. Buckley, M. S. Devlin, J. W. Kane-Gill, S. L.
Year
2024
Journal
Crit Care Med
Abstract

OBJECTIVES: To summarize the effectiveness of implementation strategies for ICU execution of recommendations from the 2013 Pain, Agitation/Sedation, Delirium (PAD) or 2018 PAD, Immobility, Sleep Disruption (PADIS) guidelines. DATA SOURCES: PubMed, CINAHL, Scopus, and Web of Science were searched from January 2012 to August 2023. The protocol was registered with PROSPERO (CRD42020175268). STUDY SELECTION: Articles were included if: 1) design was randomized or cohort, 2) adult population evaluated, 3) employed recommendations from greater than or equal to two PAD/PADIS domains, and 4) evaluated greater than or equal to 1 of the following outcome(s): short-term mortality, delirium occurrence, mechanical ventilation (MV) duration, or ICU length of stay (LOS). DATA EXTRACTION: Two authors independently reviewed articles for eligibility, number of PAD/PADIS domains, quality according to National Heart, Lung, and Blood Institute assessment tools, implementation strategy use (including Assess, prevent, and manage pain; Both SAT and SBT; Choice of analgesia and sedation; Delirium: assess, prevent, and manage; Early mobility and exercise; Family engagement and empowerment [ABCDEF] bundle) by Cochrane Effective Practice and Organization of Care (EPOC) category, and clinical outcomes. Certainty of evidence was assessed using Grading of Recommendations Assessment, Development, and Evaluation. DATA SYNTHESIS: Among the 25 of 243 (10.3%) full-text articles included ( n = 23,215 patients), risk of bias was high in 13 (52%). Most studies were cohort ( n = 22, 88%). A median of 5 (interquartile range [IQR] 4-7) EPOC strategies were used to implement recommendations from two (IQR 2-3) PAD/PADIS domains. Cohort and randomized studies were pooled separately. In the cohort studies, use of EPOC strategies was not associated with a change in mortality (risk ratio [RR] 1.01; 95% CI, 0.9-1.12), or delirium (RR 0.92; 95% CI, 0.82-1.03), but was associated with a reduction in MV duration (weighted mean difference [WMD] -0.84 d; 95% CI, -1.25 to -0.43) and ICU LOS (WMD -0.77 d; 95% CI, -1.51 to 0.04). For randomized studies, EPOC strategy use was associated with reduced mortality and MV duration but not delirium or ICU LOS. CONCLUSIONS: Using multiple implementation strategies to adopt PAD/PADIS guideline recommendations may reduce mortality, duration of MV, and ICU LOS. Further prospective, controlled studies are needed to identify the most effective strategies to implement PAD/PADIS recommendations.

PMID

PMID: 38193764

PMCID: PMC10939834

NIHMS1957979

Keywords

Adult
Humans
*Critical Care/methods
Intensive Care Units
Pain
Pain Management
*Delirium/prevention & control

Page(s)
Issue

Search:
Total Records Found: 6272, showing 100 per page
TitleAuthorsJournalYearKeywords
Precipitants of Delirium in Older Inpatients Admitted in Surgery for Post-Fall Hip Fracture: An Observational Study. Levinoff, E. Try, A. Chabot, J. Lee, L. Zukor, D. Beauchet, O. The Journal of Frailty & Aging 2018

aged
delirium
female
hip fracture
hospital patient
human
male
postoperative complication
Quebec
retrospective study
risk factor
very elderly

Neural predisposing factors of postoperative delirium in elderly patients with femoral neck fracture. Kyeong, S. Shin, J. E. Yang, K. H. Lee, W. S. Chung, T. S. Kim, J. J. Sci Rep 2018
Music intervention to prevent delirium among older patients admitted to a trauma intensive care unit and a trauma orthopaedic unit. Johnson, K. Fleury, J. McClain, D. Intensive Crit Care Nurs 2018

Delirium
Diastolic pressure
Heart rate
Music listening
Neuroscience of music
Non-pharmacologic approach
Pharmacologic approach
Roy Adaptation Model
Systolic blood pressure

Delirium as a predictor of mortality in US Medicare beneficiaries discharged from the emergency department: a national claims-level analysis up to 12 months. Israni, J. Lesser, A. Kent, T. Ko, K. BMJ Open 2018

claims data
delirium
geriatrics
mortality

An evaluation of patient-specific characteristics on attainment of target sedation in an intensive care unit. Humphrey, M. Everhart, S. Kosmisky, D. Anderson, W. E. Heart Lung 2018

Agitation
Critical care
Delirium
Monitoring
Rass
Sedation

An assistant workforce to improve screening rates and quality of care for older patients in the emergency department: findings of a pre- post, mixed methods study. Hullick, C. Conway, J. Higgins, I. Hewitt, J. Stewart, B. Dilworth, S. Attia, J. BMC Geriatr 2018

Assessment, nursing
Caregivers
Comprehensive geriatric assessment
Delirium
Delirium prevention
Emergency department, aged
Emergency nursing
Emergency services, hospital
Older person
Screening
Standard of care

Cycling of Dexmedetomidine May Prevent Delirium After Liver Transplantation. Hong, K. S. Kim, N. R. Song, S. H. Hong, G. Transplant Proc 2018
Risk Factors for Postoperative Delirium After Gastrectomy in Gastric Cancer Patients. Honda, S. Furukawa, K. Nishiwaki, N. Fujiya, K. Omori, H. Kaji, S. Makuuchi, R. Irino, T. Tanizawa, Y. Bando, E. Kawamura, T. Terashima, M. World J Surg 2018
Factors Associated with the Effectiveness of Intravenous Administration of Chlorpromazine for Delirium in Patients with Terminal Cancer. Hasuo, H. Kanbara, K. Fujii, R. Uchitani, K. Sakuma, H. Fukunaga, M. J Palliat Med 2018

delirium
intravenous chlorpromazine
motoric subtype
shock index
terminal cancer

An evaluation of single question delirium screening tools in older emergency department patients. Han, J. H. Wilson, A. Schnelle, J. F. Dittus, R. S. Wesley Ely, E. American Journal of Emergency Medicine 2018

adult
article
consultation
delirium
diagnostic test accuracy study
diagnostic value
DSM-IV-TR
emergency physician
emergency ward
female
human
major clinical study
male
mental health
observational study
prospective study
psychiatrist
scientist
speech
thinking

A contemporary population-based analysis of the incidence, cost, and outcomes of postoperative delirium following major urologic cancer surgeries. Ha, A. Krasnow, R. E. Mossanen, M. Nagle, R. Hshieh, T. T. Rudolph, J. L. Chang, S. L. Urol Oncol 2018

Costs
Cystectomy
Incidence
Nephrectomy
Outcomes
Postoperative delirium

Risk Factors and Outcomes of Delirium in Older Patients Admitted to Postacute Care with and without Dementia. Gual, N. Morandi, A. Perez, L. M. Britez, L. Burbano, P. Man, F. Inzitari, M. Dement Geriatr Cogn Disord 2018

Crisis management
Delirium
Delirium superimposed on dementia
Emergency department
Intermediate care
Risk factors
Skilled nursing facilities

Frailty Assessment to Help Predict Patients at Risk of Delirium When Consulting the Emergency Department. Giroux, M. Sirois, M. J. Boucher, V. Daoust, R. Gouin, E. Pelletier, M. Berthelot, S. Voyer, P. Emond, M. J Emerg Med 2018

delirium
emergency department
frailty
length of stay
older adults

Performance of the French version of the 4AT for screening the elderly for delirium in the emergency department. Gagne, A. J. Voyer, P. Boucher, V. Nadeau, A. Carmichael, P. H. Pelletier, M. Gouin, E. Berthelot, S. Daoust, R. Wilchesky, M. Richard, H. Pelletier, I. Ballard, S. Lague, A. Emond, M.` CJEM 2018
Early rehabilitation to prevent postintensive care syndrome in patients with critical illness: a systematic review and meta-analysis Fuke, R. Hifumi, T. Kondo, Y. Hatakeyama, J. Takei, T. Yamakawa, K. Inoue, S. Nishida, O. BMJ Open 2018

early rehabilitation
intensive care unit
post-intensive care syndrome
sepsis

Effects of closed-loop intravenous anesthesia guided by Bispectral Index in adult patients on emergence delirium: A randomized controlled study. Cotoia, A. Mirabella, L. Beck, R. Matrella, P. Assenzo, V. Hazot, T. C. Cinnella, G. Liu, N. Dambrosio, M. Minerva Anestesiol 2018

epidural catheter
suture
anesthetic agent
atropine
cisatracurium
desflurane
etilefrine
levobupivacaine
morphine
neostigmine
propofol
remifentanil
sevoflurane
adult
aged
anesthesia
article
bispectral index
breathing rate
controlled study
double blind procedure
drug withdrawal
emergence agitation
extubation
female
human
hypotension
major clinical study
male
middle aged
Mini Mental State Examination
neuromuscular function
operative blood loss
positive end expiratory pressure
postoperative pain
prospective study
randomized controlled trial
scoring system
titrimetry
urologic surgery
chirocaine
diprivan
effortil
intrastigmina
nimbex
sevorane
suprane
ultiva

Prevalence and risk factors related to haloperidol use for delirium in adult intensive care patients: the multinational AID-ICU inception cohort study. Collet, M. O. Caballero, J. Sonneville, R. Bozza, F. A. Nydahl, P. Schandl, A. Woien, H. Citerio, G. van den Boogaard, M. Hastbacka, J. Haenggi, M. Colpaert, K. Rose, L. Barbateskovic, M. Lange, T. Jensen, A. Krog, M. B. Egerod, I. Nibro, H. L. Wetterslev Intensive Care Med 2018

Cohort
Critical care
Delirium
Haloperidol
Icu

Latent class analysis of the multivariate Delirium Index in long-term care settings. Ciampi, A. Bai, C. Dyachenko, A. McCusker, J. Cole, M. G. Belzile, E. Int Psychogeriatr 2018

Delirium Index
delirium
hidden Markov model
latent class
long-term care
longitudinal
old

Cognitive Decline after Delirium in Patients Undergoing Cardiac Surgery. Brown, C. H. th Probert, J. Healy, R. Parish, M. Nomura, Y. Yamaguchi, A. Tian, J. Zehr, K. Mandal, K. Kamath, V. Neufeld, K. J. Hogue, C. W. Anesthesiology 2018
Screening for Delirium: Development and Validation of the Buffalo Delirium Scale for Use in a Home-Based Hospice Setting. Breier, J. M. Meier, S. T. Kerr, C. W. Wright, S. T. Grant, P. C. Depner, R. M. Am J Hosp Palliat Care 2018

delirium
end of life
hospice care
psychometrics

Improving Geriatric Care Processes on Two Medical-Surgical Acute Care Units: A Pilot Study. Booth, K. A. Simmons, E. E. Viles, A. F. Gray, W. A. Kennedy, K. R. Biswal, S. H. Lowe, J. A. Xhaja, A. Kennedy, R. E. Brown, C. J. Flood, K. L. J Healthc Qual 2018
Screening for delirium with the Intensive Care Delirium Screening Checklist (ICDSC): Symptom profile and utility of individual items in the identification of delirium dependent on the level of sedation. Boettger, S. Meyer, R. Richter, A. Fernandez, S. F. Rudiger, A. Schubert, M. Jenewein, J. Nunez, D. G. Palliat Support Care 2018

4th edition
text revision (DSM-IV-TR)
Delirium
Diagnostic and Statistical Manual
Intensive Care Delirium Screening Checklist (ICDSC)
Richmond Agitation and Sedation Scale (RASS)
intensive care unit (ICU)
phenomenology

The impact of psychomotor subtypes and duration of delirium on 6-month mortality in hip-fractured elderly patients. Bellelli, G. Carnevali, L. Corsi, M. Morandi, A. Zambon, A. Mazzola, P. Galeazzi, M. Bonfanti, A. Massariello, F. Szabo, H. Oliveri, G. Haas, J. d'Oro, L. C. Annoni, G. Int J Geriatr Psychiatry 2018

delirium
hip fracture
psychomotor subtype
surgery
survival

Validation of the Brief Confusion Assessment Method for screening delirium in elderly medical patients in a German emergency department. Baten, V. Busch, H. J. Busche, C. Schmid, B. Heupel-Reuter, M. Perlov, E. Brich, J. Kloppel, S. Acad Emerg Med 2018

bCAM
Delirium
Emergency Department
Geriatric medicine
Germany
Validity

Association of intensive care unit delirium with sleep disturbance and functional disability after critical illness: an observational cohort study. Altman, M. T. Knauert, M. P. Murphy, T. E. Ahasic, A. M. Chauhan, Z. Pisani, M. A. Ann Intensive Care 2018

Activities of daily living
Critical care
Delirium
Disability
Post-ICU
Post-hospital
Sleep disturbance

Impact of Delirium on Patients Hospitalized for Myocardial Infarction: a Propensity Score Analysis of The National Inpatient Sample. Abdullah, A. Eigbire, G. Salama, A. Wahab, A. Awadalla, M. Hoefen, R. Alweis, R. Clin Cardiol 2018

ICD-9-CM codes
comorbidities
“Altered mental status”
“Delirium”
“Myocardial Infarction

The role of geriatrician-hospitalists in the care of older adults: A retrospective cohort study. Sinvani, L. Carney, M. Kozikowski, A. Smilios, C. Patel, V. Qiu, G. Zhang, M. Babalola, O. Kandov, Y. Rosenberg, D. Wolf-Klein, G. Pekmezaris, R. Arch Gerontol Geriatr 2018

indwelling catheter
urinary catheter
benzodiazepine
cholinergic receptor blocking agent
aged
article
Charlson Comorbidity Index
clinical outcome
clinical practice
cohort analysis
comorbidity
delirium
documentation
female
geriatric care
geriatrician
hospital admission
hospital discharge
hospital readmission
human
length of stay
major clinical study
male
medical staff
outcome assessment
patient compliance
priority journal
retrospective study
safety
tertiary care center

Clinical and laboratory characteristics associated with referral of hospitalized elderly to palliative care. Arcanjo, S. P. Saporetti, L. A. Curiati, J. A. E. Jacob-Filho, W. Avelino-Silva, T. J. Einstein (Sao Paulo) 2018
Intraoperative cerebral oximetry-based management for optimizing perioperative outcomes: a meta-analysis of randomized controlled trials. Zorrilla-Vaca, A. Healy, R. Grant, M. C. Joshi, B. Rivera-Lara, L. Brown, C. Mirski, M. A. Canadian Journal of Anesthesia 2018

ISRCTN01707446
ISRCTN23557269
NCT02155868
article
cerebral oximetry
clinical outcome
hospitalization
human
incidence
intensive care unit
intraoperative monitoring
length of stay
meta analysis
outcome assessment
oximetry
patient care
patient safety
postoperative cognitive dysfunction
postoperative delirium
priority journal
randomized controlled trial (topic)
systematic review

Postoperative delirium in total knee and hip arthroplasty patients: a study of perioperative modifiable risk factors. Weinstein, S. M. Poultsides, L. Baaklini, L. R. Mörwald, E. E. Cozowicz, C. Saleh, J. N. Arrington, M. B. Poeran, J. Zubizarreta, N. Memtsoudis, S. G. British Journal of Anaesthesia 2018

total hip prosthesis
benzodiazepine derivative
ketamine
opiate
adult
aged
analgesia
anesthesia
article
comorbidity
epidural anesthesia
female
general anesthesia
hip arthroplasty
hospital admission
hospitalization
human
ICD-9
major clinical study
male
medical history
medical record
neuraxial anaesthesia
observational study
patient care
perioperative period
postoperative delirium
prescription
priority journal
retrospective study
risk factor
spinal anesthesia
surgical patient
total knee arthroplasty

Impact of dexmedetomidine infusion during general anaesthesia on incidence of postoperative delirium in elderly patients after major non-cardiac surgery: study protocol of a randomised, double-blinded and placebo-controlled trial. Wang, B. J. Li, C. J. Hu, J. Li, H. J. Guo, C. Wang, Z. H. Zhang, Q. C. Mu, D. L. Wang, D. X. BMJ Open 2018

elderly
intraoperative dexmedetomidine
major non-cardiac surgery
postoperative delirium
given at academic meetings from Jiangsu Hengrui Medicine, China, and Yichang
Humanwell Pharmaceutical, China. D-LM is the primary investigator of the present
study, which was supported by Beijing Excellent Talent Support Program.

Can education improve clinical practice concerning delirium in older hospitalised patients? Results of a pre-test post-test study on an educational intervention for nursing staff. van Velthuijsen, E. L. Zwakhalen, S. M. G. Warnier, R. M. J. Ambergen, T. Mulder, W. J. Verhey, F. R. J. Kempen, Gijm BMC Med Educ 2018

Delirium
Educational intervention
Hospital
PRECEDE model

Withdrawal versus continuation of long-term antipsychotic drug use for behavioural and psychological symptoms in older people with dementia. Van Leeuwen, E. Petrovic, M. van Driel, M. L. De Sutter, A. I. M. Vander Stichele, R. Declercq, T. Christiaens, T. Cochrane Database of Systematic Reviews 2018

chlorpromazine
haloperidol
levomepromazine
lorazepam
loxapine
mesoridazine
neuroleptic agent
olanzapine
perphenazine
placebo
risperidone
thioridazine
tiotixene
trifluoperazine
aggression
agitation
akathisia
behavior disorder
blood pressure
body equilibrium
cardiovascular disease
cognition
confusion
dementia
drug fatality
drug megadose
drug response
drug safety
drug withdrawal
extrapyramidal symptom
falling
fracture
heart rate
human
insomnia
long term care
low drug dose
lung disease
mental disease
motor dysfunction
nausea
neurologic disease
nursing home
parkinsonism
physical mobility
primary medical care
priority journal
psychosis
quality of life
relapse
restlessness
review
sedation
side effect
systematic review
tardive dyskinesia
treatment outcome
vomiting

Delirium in the Intensive Care Unit: Incidence, risk factors, and impact on outcome. Tilouche, N. Hassen, M. F. Ali, H. B. S. Jaoued, O. Gharbi, R. El Atrous, S. Indian Journal of Critical Care Medicine 2018

endotracheal tube
urinary catheter
analgesic agent
hypertensive factor
midazolam
steroid
adult
article
artificial ventilation
catheter removal
chronic obstructive lung disease
clinical evaluation
conscious sedation
controlled study
delirium
disease association
disease duration
female
heart arrest
hospital admission
hospital mortality
human
hypertension
incidence
length of stay
major clinical study
male
medical history
medical intensive care unit
medical staff
observational study
outcome assessment
patient risk
prospective study
risk assessment
risk factor
Tunisia

Should This Patient Receive Prophylactic Medication to Prevent Delirium?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center. Tess, A. V. Mattison, M. L. P. Leo, J. R. Reynolds, E. E. Ann Intern Med 2018
Use of the CAM-ICU during daily sedation stops in mechanically ventilated patients as assessed and experienced by intensive care nurses - A mixed-methods study. Steinseth, E. B. Hoye, S. Hov, R. Intensive Crit Care Nurs 2018

Assessment
Confusion Assessment Method for Intensive Care Unit
Experiences
Intensive care nurses

Risk factors and outcome of postoperative delirium after transcatheter aortic valve replacement. Stachon, P. Kaier, K. Zirlik, A. Reinohl, J. Heidt, T. Bothe, W. Hehn, P. Zehender, M. Bode, C. von Zur Muhlen, C. Clin Res Cardiol 2018

In-hospital mortality
Outcome
Postoperative delirium
Transcatheter aortic valve replacement (TAVR)

Neurological Sequelae and Clinical Outcomes After Lung Transplantation. Smith, P. J. Stonerock, G. L. Ingle, K. K. Saulino, C. K. Hoffman, B. Wasserman, B. Blumenthal, J. A. Palmer, S. M. Klapper, J. A. Hartwig, M. G. Esposito, V. R. Snyder, L. D. Transplant Direct 2018
Comparison of Ketamine- Versus Nonketamine-Based Sedation on Delirium and Coma in the Intensive Care Unit. Shurtleff, V. Radosevich, J. J. Patanwala, A. E. Journal of Intensive Care Medicine 2018

adult
analgesia
article
artificial ventilation
cohort analysis
coma
controlled clinical trial
controlled study
delirium
drug therapy
female
human
incidence
infusion
intensive care unit
major clinical study
male
outcome assessment
retrospective study
sedation
United States
university hospital
ventilated patient
dexmedetomidine
ketamine
propofol
sedative agent

Postoperative delirium in elderly patients with critical limb ischemia undergoing major leg amputation: a retrospective study. Shin, Y. H. Yoon, J. S. Jeon, H. J. Kim, Y. B. Kim, Y. S. Park, J. Y. Korean J Anesthesiol 2018

Amputation
Delirium
Elderly patients
Ischemia
Leg

The validity and reliability of the Arabic version of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU): A prospective cohort study Selim, A. Kandeel, N. Elokl, M. Khater, M. S. Saleh, A. N. Bustami, R. Ely, E. W. Int J Nurs Stud 2018

Delirium
Diagnosis
Intensive care unit
Sensitivity and specificity

Validation of Caregiver-Centered Delirium Detection Tools: A Systematic Review. Rosgen, B. Krewulak, K. Demiantschuk, D. Ely, E. W. Davidson, J. E. Stelfox, H. T. Fiest, K. M. J Am Geriatr Soc 2018

caregiver
delirium
family
hospital
screening

Study protocol to assess the effectiveness and safety of a flexible family visitation model for delirium prevention in adult intensive care units: a cluster-randomised, crossover trial (The ICU Visits Study). Rosa, R. G. Falavigna, M. Robinson, C. C. da Silva, D. B. Kochhann, R. de Moura, R. M. Santos, M. M. S. Sganzerla, D. Giordani, N. E. Eugenio, C. Ribeiro, T. Cavalcanti, A. B. Bozza, F. Azevedo, L. C. P. Machado, F. R. Salluh, J. I. F. Pellegrini, J. A. S BMJ Open 2018

critical care
delirium
family
health personnel
intensive care unit

Attention, arousal and other rapid bedside screening instruments for delirium in older patients: a systematic review of test accuracy studies. Quispel-Aggenbach, D. W. P. Holtman, G. A. Zwartjes, Haht Zuidema, S. U. Luijendijk, H. J. Age & Ageing 2018
Use of haloperidol versus atypical antipsychotics and risk of in-hospital death in patients with acute myocardial infarction: Cohort study Park, Y. Bateman, B. T. Kim, D. H. Hernandez-Diaz, S. Patorno, E. Glynn, R. J. Mogun, H. Huybrechts, K. F. BMJ 2018

acetylsalicylic acid
antiarrhythmic agent
anticoagulant agent
atypical antipsychotic agent
benzodiazepine derivative
haloperidol
heparin
nitric acid derivative
olanzapine
opiate
quetiapine
risperidone
acute heart infarction
adult
aged
article
Caucasian
Charlson Comorbidity Index
cohort analysis
comorbidity
controlled study
delirium
dementia
drug fatality
drug safety
female
hazard ratio
heart failure
high risk patient
hospital admission
hospital discharge
hospital mortality
human
intensive care unit
intention to treat analysis
length of stay
major clinical study
male
non ST segment elevation myocardial infarction
nursing home
percutaneous coronary intervention
priority journal
propensity score
risk factor
sensitivity analysis
ST segment elevation myocardial infarction
survival rate
treatment duration
United States
very elderly

Postictal delirium and violent behavior in patients with post-neurosurgical epilepsy. Oueslati, B. Fekih-Romdhane, F. Ridha, R. World Neurosurg 2018

epilepsy
neurosurgery
postictal delirium
violence

Factor Analysis of Delirium in Elderly, Using the Korean Version of Delirium Rating Scale-Revised-98. Noh, G. Kwon, I. Lee, M. Ahn, S. H. Kim, J. L. Psychiatry Investigation 2018

Aged
Delirium
Factor analysis
Statistical

Flexible Versus Restrictive Visiting Policies in ICUs: A Systematic Review and Meta-Analysis. Nassar Junior, A. P. Besen, Bamp Robinson, C. C. Falavigna, M. Teixeira, C. Rosa, R. G. Crit Care Med 2018
Effectiveness of non-pharmacological strategies for managing delirium in hospitalized postoperative adults: An umbrella review protocol. McNeil, J. Denis, A. M. Michel, U. Concert, C. M. JBI Database of Systematic Reviews and Implementation Reports 2018

adult
clinical effectiveness
clinical protocol
conservative treatment
data analysis
delirium
hospital patient
human
outcome assessment
patient selection
postoperative period
review
study design
systematic review

Genome-wide association identifies a novel locus for delirium risk. McCoy, T. H. Hart, K. Pellegrini, A. Perlis, R. H. Neurobiology of Aging 2018

adult
article
attention
biobank
consultation
controlled study
delirium
electronic health record
female
genetic association
genetic variation
genome-wide association study
human
major clinical study
male
Massachusetts
phenotype
psychiatry
university hospital
endogenous compound
interleukin derivative

Risk factors for postoperative delirium in patients undergoing free flap reconstruction for oral cancer. Makiguchi, T. Yokoo, S. Kurihara, J. Int J Oral Maxillofac Surg 2018

delirium
free flap reconstruction
oral cancer
risk factors

Risk factors for mortality in elderly patients with hip fractures: a meta-analysis of 18 studies. Liu, Y. Wang, Z. Xiao, W. Aging Clin Exp Res 2018

Elderly
Hip fracture
Meta-analysis
Mortality
Risk factor

Inflammatory markers in postoperative delirium (POD) and cognitive dysfunction (POCD): A meta-analysis of observational studies. Liu, X. Yu, Y. Zhu, S. PLoS One 2018
Systematic review of prediction models for delirium in the older adult inpatient. Lindroth, H. Bratzke, L. Purvis, S. Brown, R. Coburn, M. Mrkobrada, M. Chan, M. T. V. Davis, D. H. J. Pandharipande, P. Carlsson, C. M. Sanders, R. D. BMJ Open 2018

delirium
geriatric medicine
statistic

Age is the Most Significantly Associated Risk Factor with the Development of Delirium in Patients Hospitalized for More Than Five Days in Surgical Wards: Retrospective Cohort Study. Kubota K, Suzuki A, Ohde S, Yamada U, Hosaka T, Okuno F, Fujitani I, Koitabashi A, Shimada G, Kishida A Annals of surgery 2017

nitrogen
urea
adult
age
aged
article
cerebrovascular disease
cohort analysis
delirium
female
hospital patient
human
immobilization
intensive care
length of stay
major clinical study
male
mortality rate
outcome assessment
pain
priority journal
retrospective study
risk factor
surgical ward
urea nitrogen blood level

Reduced ex vivo release of pro-inflammatory cytokines and elevated plasma interleukin-6 are inflammatory signatures of post-stroke delirium. Kowalska, K. Klimiec, E. Weglarczyk, K. Pera, J. Slowik, A. Siedlar, M. Dziedzic, T. J Neuroinflammation 2018

Cytokines
Delirium
Inflammation
Stroke

Parkinson's disease-related non-motor features as risk factors for post-operative delirium in spinal surgery. Kim, K. H. Kang, S. Y. Shin, D. A. Yi, S. Ha, Y. Kim, K. N. Sohn, Y. H. Lee, P. H. PLoS One 2018
Relationships between markers of neurologic and endothelial injury during critical illness and long-term cognitive impairment and disability. Hughes, C. G. Patel, M. B. Brummel, N. E. Thompson, J. L. McNeil, J. B. Pandharipande, P. P. Jackson, J. C. Chandrasekhar, R. Ware, L. B. Ely, E. W. Girard, T. D. Intensive Care Medicine 2018

NCT00392795
biological marker
brain derived neurotrophic factor
cell adhesion molecule
endothelial leukocyte adhesion molecule 1
interleukin 6
protein S100B
ubiquitin thiolesterase
adult
aged
APACHE
article
blood brain barrier
cognitive defect
cohort analysis
critical illness
critically ill patient
daily life activity
diagnostic accuracy
disability
disease association
disease severity
endothelium injury
enzyme linked immunosorbent assay
executive function
female
follow up
hospital admission
hospital discharge
human
intensive care unit
long term care
major clinical study
male
middle aged
neurologic disease
outcome assessment
prospective study
respiratory failure
shock
survivor

Incidence, Risk Factors, and Sequelae of Post-kidney Transplant Delirium. Haugen, C. E. Mountford, A. Warsame, F. Berkowitz, R. Bae, S. G. Thomas A Brown, C. H. th Brennan, D. C. Neufeld, K. J. Carlson, M. C. Segev, D. L. McAdams-DeMarco, M. J Am Soc Nephrol 2018

clinical
epidemiology
geriatric nephrology
kidney transplantation
transplant outcomes

Evaluation of an Intervention With Nurses for Delirium Detection After Cardiac Surgery. Fraser, V. Cossette, S. Mailhot, T. Brisebois, A. Dubé, V. Worldviews on evidence-based nursing 2018

adult
Canada
cardiovascular surgery
checklist
delirium
devices
female
human
information processing
intensive care unit
male
mass screening
nursing
organization and management
procedures
questionnaire
standards
tertiary care center

Delirium clinical motor subtypes: a narrative review of the literature and insights from neurobiology. FitzGerald JM Aging & mental health 2017

Screening and diagnosis
delirium
mental health
mental health assessments
research methods

Are antipsychotics effective for the prevention of postoperative delirium? Castro, V. Guinguis, R. Carrasco, M. Medwave 2018
Measuring mobility in older hospital patients with cognitive impairment using the de Morton Mobility Index. Braun, T. Gruneberg, C. Thiel, C. Schulz, R. J. BMC Geriatr 2018

Dementia
Geriatric assessment
Mobility limitation
Outcome assessment
Physiotherapy
Psychometrics
Rehabilitation
de Morton Mobility Index

Haloperidol for delirium in critically ill patients – protocol for a systematic review. Barbateskovic, M. Kraus, S. R. Collet, M. O. Mathiesen, O. Jakobsen, J. C. Perner, A. Wetterslev, J. Acta Anaesthesiol Scand 2018

haloperidol
placebo
article
critically ill patient
data analysis
data extraction
data synthesis
delirium
drug efficacy
human
information processing
information retrieval
outcome assessment
priority journal
systematic review

Dexmedetomidine vs morphine and midazolam in the prevention and treatment of delirium after adult cardiac surgery; a randomized, double-blinded clinical trial. Azeem, T. M. A. Yosif, N. E. Alansary, A. M. Esmat, I. M. Mohamed, A. K. Saudi J Anaesth 2018

Dexmedetomidine
midazolam
morphine
postoperative delirium

Psychometric properties of the Arabic version of the confusion assessment method for the intensive care unit (CAM-ICU). Aljuaid, M. H. Deeb, A. M. Dbsawy, M. Alsayegh, D. Alotaibi, M. Arabi, Y. M. BMC Psychiatry 2018

Arabic
Cam-icu
Cognition
Critical care
Delirium
Geriatric
Inattention
Mechanical ventilation

Postoperative delirium, learning, and anesthetic neurotoxicity: Some perspectives and directions. Mutch, W. A. El-Gabalawy, R. M. Graham, M. R. Frontiers in Neurology 2018

adult
aged
animal experiment
animal model
article
classification
clinical trial (topic)
congenital malformation
female
intraoperative monitoring
learning
male
neurotoxicity
nonhuman
peroperative complication
postoperative cognitive dysfunction
postoperative delirium
primate
surgery
biological product

Designing a nurse-delivered delirium bundle: What intensive care unit staff, survivors, and their families think? Bannon, L. McGaughey, J. Clarke, M. McAuley, D. F. Blackwood, B. Aust Crit Care 2018

Delirium
Focus groups
Non-pharmacological
Perceptions

The 2014 updated version of the Confusion Assessment Method for the Intensive Care Unit compared to the 5th version of the Diagnostic and Statistical Manual of Mental Disorders and other current methods used by intensivists. Chanques, G. Ely, E. W. Garnier, O. Perrigault, F. Eloi, A. Carr, J. Rowan, C. M. Prades, A. de Jong, A. Moritz-Gasser, S. Molinari, N. Jaber, S. Ann Intensive Care 2018

Critical care
Delirium
Intensive care unit

Effect of a 24-h extended visiting policy on delirium in critically ill patients. Westphal, G. A. Moerschberger, M. S. Vollmann, D. D. Inacio, A. C. Machado, M. C. Sperotto, G. Cavalcanti, A. B. Koenig, A. Intensive Care Medicine 2018
Effect of Sedation Regimen on Weaning from Mechanical Ventilation in the Intensive Care Unit. Nunes, S. L. Forsberg, S. Blomqvist, H. Berggren, L. Sorberg, M. Sarapohja, T. Wickerts, C. J. Clin Drug Investig 2018
Validation of the korean version of the delirium motor subtype scale. Kim, H. Lee, M. Kwon, I. S. Kim, J. L. Psychiatry Investigation 2018

aged
alertness
apathy
article
brain injury
consultation
delirium
Delirium Motor Subtype Scale
Delirium Rating Scale
Delirium Symptom Interview
drug intoxication
endocrine disease
female
human
Korean (people)
Korean version of the Delirium Rating Scale Revised 98
lethargy
major clinical study
male
medical information
motor dysfunction assessment
neoplasm
prospective study
reliability
restlessness
seizure
speech disorder
validation study

e-Screening revolution: A novel approach to developing a delirium screening tool in the intensive care unit. Eeles, E. Gunn, H. Sutt, A. L. Pinsker, D. Flaws, D. Jarrett, P. Lye, I. Fraser, J. F. Australasian Journal on Ageing 2018

delirium
diagnostic techniques
intensive care units
mobile applications
neurological
screening

Sedation Intensity in the First 48 Hours of Mechanical Ventilation and 180-Day Mortality: A Multinational Prospective Longitudinal Cohort Study. Shehabi, Y. Bellomo, R. Kadiman, S. Ti, L. K. Howe, B. Reade, M. C. Khoo, T. M. Alias, A. Wong, Y. L. Mukhopadhyay, A. McArthur, C. Seppelt, I. Webb, S. A. Green, M. Bailey, M. J. Crit Care Med 2018
Screening for delirium with the Intensive Care Delirium Screening Checklist (ICDSC): a re-evaluation of the threshold for delirium. Boettger, S. Garcia Nunez, D. Meyer, R. Richter, A. Rudiger, A. Schubert, M. Jenewein, J. Swiss Medical Weekly 2018
Risk Factors of Postoperative Delirium in the Intensive Care Unit After Liver Transplantation. Lee, H. Oh, S. Y. Yu, J. H. Kim, J. Yoon, S. Ryu, H. G. World J Surg 2018
Risk Factors for Postoperative Delirium After Deep Brain Stimulation Surgery for Parkinson's Disease. Tanaka, M. Tani, N. Maruo, T. Oshino, S. Hosomi, K. Saitoh, Y. Kishima, H. World Neurosurg 2018

Deep Brain Stimulation
Parkinson’s Disease
Postoperative Delirium
Risk Factor

The relationship of delirium and risk factors in cardiology intensive care unit patients with the nursing workload. Ozturk Birge, A. Beduk, T. J Clin Nurs 2018

Critical Care
Intensive Care
Management
Medical Nursing
Nursing
Risk Assessment

Protocol for a single-centre prospective observational study of postoperative delirium following total joint arthroplasties among South East Asians. Abdullah, H. R. Tan, S. R. Lee, S. J. Bin Abd Razak, H. R. Seet, R. H. Ying, H. Sethi, E. Sim, E. Y. BMJ Open 2018

*delirium
*incidence
*postoperative
*total joint arthroplasty

Preoperative statins are associated with a reduced risk of postoperative delirium following vascular surgery. Lee, D. S. Lee, M. Y. Park, C. M. Kim, D. I. Kim, Y. W. Park, Y. J. PLoS One 2018
Predisposing and precipitating factors for delirium in community-dwelling older adults admitted to hospital with this condition: A prospective case series. Magny, E. Le Petitcorps, H. Pociumban, M. Bouksani-Kacher, Z. Pautas, É Belmin, J. Bastuji-Garin, S. Lafuente-Lafuente, C. PLoS One 2018

aged
article
cognitive defect
community care
dehydration
delirium
disease predisposition
electrolyte disturbance
emergency care
female
geriatric care
geriatrician
hospital admission
human
hyponatremia
lung infection
major clinical study
male
mental health
neurologic disease
patient assessment
personalized medicine
prospective study
urinary tract infection
very elderly

Predicting excess cost for older inpatients with clinical complexity: A retrospective cohort study examining cognition, comorbidities and complications Bail, K. Draper, B. Berry, H. Karmel, R. Goss, J. PLoS One 2018

adult
age
aged
article
Australia
cognition
cohort analysis
comorbidity
decubitus
delirium
dementia
disease severity
female
hospital admission
hospital patient
hospitalization cost
human
length of stay
linear regression analysis
major clinical study
male
nursing care
pneumonia
prediction
public hospital
retrospective study
sex
urinary tract infection

Pilot Study of a Two-Step Delirium Detection Protocol Administered By Certified Nursing Assistants, Physicians, and Registered Nurses. Fick, D. M. Inouye, S. K. McDermott, C. Zhou, W. Ngo, L. Gallagher, J. McDowell, J. Penrod, J. Siuta, J. Covaleski, T. Marcantonio, E. R. J Gerontol Nurs 2018
Perioperative hyperglycaemia and neurocognitive outcome after surgery: a systematic review. Hermanides, J. Qeva, E. Preckel, B. Bilotta, F. Minerva Anestesiol 2018
Low-dose Nocturnal Dexmedetomidine Prevents ICU Delirium: A Randomized, Placebo-controlled Trial. Skrobik, Y. Duprey, M. S. Hill, N. S. Devlin, J. W. Am J Respir Crit Care Med 2018

delirium, sleep, intensive care, dexmedetomidine, randomized controlled trial

Low peripheral levels of insulin growth factor-1 are associated with high incidence of delirium among elderly patients: A systematic review and meta-analysis. Li, D. J. Tseng, P. T. Stubbs, B. Chen, T. Y. Lin, P. Y. Chen, S. L. Thompson, T. Adamis, D. Chu, C. S. Arch Gerontol Geriatr 2018

Biomarker
Delirium
Elderly
Igf-1
Meta-analysis

Is anemia associated with cognitive impairment and delirium among older acute surgical patients? Myint, P. K. Owen, S. McCarthy, K. Pearce, L. Moug, S. J. Stechman, M. J. Hewitt, J. Carter, B. Geriatrics & Gerontology International 2018

anemia
cognitive impairment
delirium
older surgical patients

Intraoperative Sedation With Dexmedetomidine is Superior to Propofol for Elderly Patients Undergoing Hip Arthroplasty: A Prospective Randomized Controlled Study. Mei, B. Meng, G. Xu, G. Cheng, X. Chen, S. Zhang, Y. Zhang, M. Liu, X. Gu, E. Clin J Pain 2018
Infrared pupillometry helps to detect and predict delirium in the post-anesthesia care unit. Yang E, Kreuzer M, Hesse S, Davari P, Lee SC, García PS Journal of clinical monitoring and computing 2017

PLR-200
pupillometer
adult
aged
article
clinical article
confusion assessment method for the intensive care unit score
delirium
female
general anesthesia
human
informed consent
infrared pupillometry
male
observational study
priority journal
prospective study
pupil
pupillometry
receiver operating characteristic
recovery room
scoring system

Influence of Physical Restraint on Delirium of Adult Patients in ICU: A Nested Case-Control Study. Pan, Y. Jiang, Z. Changrong, Y. Wang, L. Zhang, J. Zhou, J. Tao, M. Quan, M. Wu, Q. J Clin Nurs 2018

Delirium
Intensive Care Unit
Nested Case-control Study
Restraint, Physical

Incidence of delirium in the Canadian emergency department and its consequences on hospital length of stay: A prospective observational multicentre cohort study. Émond, M. Boucher, V. Carmichael, P. H. Voyer, P. Pelletier, M. Gouin, É Daoust, R. Berthelot, S. Lamontagne, M. E. Morin, M. Lemire, S. Minh Vu, T. T. Nadeau, A. Rheault, M. Juneau, L. Le Sage, N. Lee, J. BMJ Open 2018

aged
American
article
clinical assessment
cohort analysis
controlled study
crowding (area)
delirium
emergency ward
feedback system
female
functional status
human
incidence
length of stay
major clinical study
male
multicenter study
multivariate analysis
prospective study
telephone interview

Impact of timing and duration of postoperative delirium: a retrospective observational study Lee, H. Ju, J. W. Oh, S. Y. Kim, J. Jung, C. W. Ryu, H. G. Surgery 2018
Frequency and risk factors for subsyndromal delirium in an intensive care unit. Yamada, C. Iwawaki, Y. Harada, K. Fukui, M. Morimoto, M. Yamanaka, R. Intensive Crit Care Nurs 2018

Delirium
Intensive Care Delirium Screening Checklist (ICDSC) scores
Intensive care unit (ICU)
Subsyndromal delirium (SSD)

Focusing on Inattention: The Diagnostic Accuracy of Brief Measures of Inattention for Detecting Delirium. Marra, A. Jackson, J. C. Ely, E. W. Graves, A. J. Schnelle, J. F. Dittus, R. S. Wilson, A. Han, J. H. J Hosp Med 2018
Feasibility of Cognitive Training in Critically Ill Patients: A Pilot Study. Wassenaar, A. Rood, P. Boelen, D. Schoonhoven, L. Pickkers, P. van den Boogaard, M. Am J Crit Care 2018
Evaluation of a sound environment intervention in an ICU: A feasibility study. Johansson, L. Lindahl, B. Knutsson, S. Ogren, M. Persson Waye, K. Ringdal, M. Aust Crit Care 2018

Complex intervention
Feasibility
ICU delirium
Noise
Sound

Effects of Haloperidol on Delirium in Adult Patients: A Systematic Review and Meta-analysis. Shen, Y. Z. Peng, K. Zhang, J. Meng, X. W. Ji, F. Med Princ Pract 2018
The effect of the timing and dose of dexmedetomidine on postoperative delirium in elderly patients after laparoscopic major non-cardiac surgery: A double blind randomized controlled study. Lee, C. Lee, C. H. Lee, G. Lee, J. Hwang, J. J Clin Anesth 2018

Cytokine
Delirium
Dexmedetomidine

Effect of organisational factors on the variation in incidence of delirium in intensive care unit patients: A systematic review and meta-regression analysis. Rood, P. Huisman-de Waal, G. Vermeulen, H. Schoonhoven, L. Pickkers, P. van den Boogaard, M. Aust Crit Care 2018

Critical care
Delirium
Incidence
Meta-analysis
Organisational factors
Systematic review

Effect of Administration of Ramelteon, a Melatonin Receptor Agonist, on the Duration of Stay in the ICU: A Single-Center Randomized Placebo-Controlled Trial. Nishikimi, M. Numaguchi, A. Takahashi, K. Miyagawa, Y. Matsui, K. Higashi, M. Makishi, G. Matsui, S. Matsuda, N. Crit Care Med 2018