What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Antipsychotics in the Treatment of Delirium in Critically Ill Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- Authors
- Carayannopoulos, K. L. Alshamsi, F. Chaudhuri, D. Spatafora, L. Piticaru, J. Campbell, K. Alhazzani, W. Lewis, K.
- Year
- 2024
- Journal
- Crit Care Med
- Abstract
OBJECTIVES: To conduct a systematic review and meta-analysis assessing whether the use of antipsychotic medications in critically ill adult patients with delirium impacts patient-important outcomes. DATA SOURCES: A medical librarian searched Ovid MEDLINE, EMBASE, APA PsycInfo, and Wiley’s Cochrane Library as well as clinicaltrials.gov and the World Health Organization International Clinical Trials Registry Platform up to November 2023. STUDY SELECTION: Independently and in duplicate, reviewers screened abstracts and titles for eligibility, then full text of qualifying studies. We included parallel-group randomized controlled trials (RCTs) that included critically ill adult patients with delirium. The intervention group was required to receive antipsychotic medications at any dose, whereas the control group received usual care or placebo. DATA EXTRACTION: Reviewers extracted data independently and in duplicate using a piloted abstraction form. Statistical analyses were conducted using RevMan software (version 5.4). DATA SYNTHESIS: Five RCTs ( n = 1750) met eligibility criteria. The use of antipsychotic medications compared with placebo did not increase the number of delirium- or coma-free days (mean difference 0.90 d; 95% CI, -0.32 to 2.12; moderate certainty), nor did it result in a difference in mortality, duration of mechanical ventilation, ICU, or hospital length of stay. The use of antipsychotics did not result in an increased risk of adverse events (risk ratio 1.27; 95% CI, 0.71-2.30; high certainty). Subgroup analysis of typical versus atypical antipsychotics did not identify any subgroup effect for any outcome. CONCLUSIONS: In conclusion, our systematic review and meta-analysis demonstrated with moderate certainty that there is no difference in delirium- or coma-free days when delirious critically ill adults are treated with antipsychotic medications. Further studies in the subset of patients with hyperactive delirium may be of benefit.
- PMID
PMID: 38488422
- Keywords
Antipsychotic medication
Delirium
Systematic review
Critically Ill
Cognitive Impairment
Coma
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords | |
|---|---|---|---|---|---|
| Delirium in older hospitalized patients-signs and actions: a retrospective patient record review. | Johansson, Y. A. Bergh, I. Ericsson, I. Sarenmalm, E. K. | BMC Geriatr | 2018 |
*Action by healthcare professionals |
|
| Delirium-A Framework to Improve Acute Care for Older Persons. | Inouye, S. K. | J Am Geriatr Soc | 2018 |
Acute care for elders |
|
| The minimal clinically important difference of the Richmond Agitation-Sedation Scale in patients with cancer with agitated delirium. | Hui, D. Hess, K. Dibaj, S. S. Arthur, J. Dev, R. Dalal, S. Reddy, S. Bruera, E. | Cancer | 2018 |
delirium |
|
| The use of cerebral imaging for investigating delirium aetiology. | Hijazi, Z. Lange, P. Watson, R. Maier, A. B. | Eur J Intern Med | 2018 |
Delirium |
|
| Medication Profiles of Patients with Cognitive Impairment and High Anticholinergic Burden. | Green, A. R. Reifler, L. M. Boyd, C. M. Weffald, L. A. Bayliss, E. A. | Drugs Aging | 2018 | ||
| Delirium Assessment Tools for Use in Critically Ill Adults: A Psychometric Analysis and Systematic Review. | Gelinas, C. Berube, M. Chevrier, A. Pun, B. T. Ely, E. W. Skrobik, Y. Barr, J. | Crit Care Nurse | 2018 | ||
| Postoperative Delirium in Glioblastoma Patients: Risk Factors and Prognostic Implications. | Flanigan, P. M. Jahangiri, A. Weinstein, D. Dayani, F. Chandra, A. Kanungo, I. Choi, S. Sankaran, S. Molinaro, A. M. McDermott, M. W. Berger, M. S. Aghi, M. K. | Neurosurgery | 2018 | ||
| The delirium and population health informatics cohort study protocol: ascertaining the determinants and outcomes from delirium in a whole population. | Davis, D. Richardson, S. Hornby, J. Bowden, H. Hoffmann, K. Weston-Clarke, M. Green, F. Chaturvedi, N. Hughes, A. Kuh, D. Sampson, E. Mizoguchi, R. Cheah, K. L. Romain, M. Sinha, A. Jenkin, R. Brayne, C. MacLullich, A. | BMC Geriatr | 2018 |
*Delirium |
|
| Cerebral oximetry during preoperative resuscitation in elderly patients with hip fracture: a prospective observational study. | Clemmesen, C. G. Pedersen, L. M. Hougaard, S. Andersson, M. L. Rosenkvist, V. Nielsen, H. B. Palm, H. Foss, N. B. | J Clin Monit Comput | 2018 |
Delirium |
|
| Clinical characteristics associated with the onset of delirium among long-term nursing home residents. | Cheung, E. N. M. Benjamin, S. Heckman, G. Ho, J. M. Lee, L. Sinha, S. K. Costa, A. P. | BMC Geriatr | 2018 |
*Delirium |
|
| Evaluation of a multicomponent pathway to address inpatient delirium on a neurosciences ward. | Brown, E. G. Josephson, S. A. Anderson, N. Reid, M. Lee, M. Douglas, V. C. | BMC Health Serv Res | 2018 |
*Cognitive aging |
|
| Subsyndromal delirium in the intensive care setting: Phenomenological characteristics and discrimination of subsyndromal delirium versus no and full-syndromal delirium. | Boettger S, Nuñez DG, Meyer R, Richter A, Schubert M, Jenewein J | Palliative & supportive care | 2017 |
Diagnostic and Statistical Manual of Mental Disorders |
|
| Incidence, risk factors, and clinical implications of post-operative delirium in lung transplant recipients. | Anderson, B. J. Chesley, C. F. Theodore, M. Christie, C. Tino, R. Wysoczanski, A. Ramphal, K. Oyster, M. Kalman, L. Porteous, M. K. Bermudez, C. A. Cantu, E. Kolson, D. L. Christie, J. D. Diamond, J. M. | J Heart Lung Transplant | 2018 |
acidic protein |
|
| Delirium and correlates of delirium among newly admitted elderly patients: A crosssectional study in a Saudi general hospital. | Alamri, S. H. Ashanqity, O. A. Alshomrani, A. B. Elmasri, A. H. Saeed, M. B. Yahya, S. A. Almasoud, A. I. Adam, Y. Alamoudi, H. M. Mukhtar, A. M. | Annals of Saudi Medicine | 2018 |
urinary catheter |
|
| Preoperative Cognitive Impairment As a Predictor of Postoperative Outcomes in a Collaborative Care Model. | Zietlow, K. McDonald, S. R. Sloane, R. Browndyke, J. Lagoo-Deenadayalan, S. Heflin, M. T. | J Am Geriatr Soc | 2018 |
co-management |
|
| Identifying Older Adults at Risk of Delirium Following Elective Surgery: A Systematic Review and Meta-Analysis. | Watt, J. Tricco, A. C. Talbot-Hamon, C. Pham, B. Rios, P. Grudniewicz, A. Wong, C. Sinclair, D. Straus, S. E. | J Gen Intern Med | 2018 |
delirium |
|
| Sedative Plasma Concentrations and Delirium Risk in Critical Illness. | Stollings, J. L. Thompson, J. L. Ferrell, B. A. Scheinin, M. Wilkinson, G. R. Hughes, C. G. Shintani, A. K. Ely, E. W. Girard, T. D. Pandharipande, P. P. Patel, M. B. | Ann Pharmacother | 2018 |
analgesics |
|
| A feasibility study of a randomised controlled trial to examine the impact of the ABCDE bundle on quality of life in ICU survivors. | Sosnowski, K. Mitchell, M. L. White, H. Morrison, L. Sutton, J. Sharratt, J. Lin, F. | Pilot Feasibility Stud | 2018 |
ABCDE bundle |
|
| Potentially Modifiable Risk Factors for Long-Term Cognitive Impairment After Critical Illness: A Systematic Review. | Sakusic, A. O'Horo, J. C. Dziadzko, M. Volha, D. Ali, R. Singh, T. D. Kashyap, R. Farrell, A. M. Fryer, J. D. Petersen, R. Gajic, O. Rabinstein, A. A. | Mayo Clin Proc | 2018 | ||
| Prevalence of Potentially Inappropriate Medication Use in Older Inpatients with and without Cognitive Impairment: A Systematic Review. | Redston, M. R. Hilmer, S. N. McLachlan, A. J. Clough, A. J. Gnjidic, D. | J Alzheimers Dis | 2018 |
Cognitive impairment |
|
| Identification of delirium and dementia in older medical inpatients in Tanzania: A comparison of screening and diagnostic methods. | Paddick, S. M. Lewis, E. G. Duinmaijer, A. Banks, J. Urasa, S. Tucker, L. Kisoli, A. Cletus, J. Lissu, C. Kissima, J. Dotchin, C. Gray, W. K. Muaketova-Ladinska, E. Cosker, G. Walker, R. W. | Journal of the Neurological Sciences | 2018 |
adult |
|
| Interactions between drugs and geriatric syndromes in nursing home and home care: results from Shelter and IBenC projects. | Onder, G. Giovannini, S. Sganga, F. Manes-Gravina, E. Topinkova, E. Finne-Soveri, H. Garms-Homolova, V. Declercq, A. van der Roest, H. G. Jonsson, P. V. van Hout, H. Bernabei, R. | Aging Clinical and Experimental Research | 2018 |
Delirium |
|
| Development of dementia in patients with femoral neck fracture who experience postoperative delirium-A three-year follow-up study. | Olofsson, B. Persson, M. Bellelli, G. Morandi, A. Gustafson, Y. Stenvall, M. | Int J Geriatr Psychiatry | 2018 |
cognitive impairment |
|
| Prediction and early detection of delirium in the intensive care unit by using heart rate variability and machine learning. | Oh, J. Cho, D. Park, J. Na, S. H. Kim, J. Heo, J. Shin, C. S. Kim, J. J. Park, J. Y. Lee, B. | Physiol Meas | 2018 |
Autonomic nervous system |
|
| Preoperative exercise capacity is associated with the prevalence of postoperative delirium in elective cardiac surgery. | Ogawa M, Izawa KP, Satomi-Kobayashi S, Kitamura A, Tsuboi Y, Komaki K, Ono R, Sakai Y, Tanaka H, Okita Y | Aging clinical and experimental research | 2017 |
Cardiac surgery |
|
| Effectiveness of multicomponent interventions on incidence of delirium in hospitalized older patients with hip fracture: a systematic review. | Oberai, T. Laver, K. Crotty, M. Killington, M. Jaarsma, R. | Int Psychogeriatr | 2018 |
Delirium-elderly patients |
|
| Controlled pre-post, mixed-methods study to determine the effectiveness of a national delirium clinical care standard to improve the diagnosis and care of patients with delirium in Australian hospitals: a protocol. | Mumford, V. Kulh, M. A. Hughes, C. Braithwaite, J. Westbrook, J. | BMJ Open | 2018 |
clinical governance |
|
| Incidence and Risk Factors of Postoperative Delirium following Pancreatic Surgery: Does the Administration of TJ-54 Reduce the Incidence of Delirium. | Mizuno, S. Takeuchi, S. Kishiwada, M. Mizutani, N. Matsuda, M. Sekoguchi, N. Iizawa, Y. Azumi, Y. Kuriyama, N. Usui, M. Sakurai, H. Maruyama, K. Okuda, M. Okada, M. Isaji, S. | Dig Surg | 2018 |
Delirium rating scale – Japanese version |
|
| Association of Integrated Care Coordination With Postsurgical Outcomes in High-Risk Older Adults: The Perioperative Optimization of Senior Health (POSH) Initiative. | McDonald, S. R. Heflin, M. T. Whitson, H. E. Dalton, T. O. Lidsky, M. E. Liu, P. Poer, C. M. Sloane, R. Thacker, J. K. White, H. K. Yanamadala, M. Lagoo-Deenadayalan, S. A. | JAMA Surg | 2018 | ||
| Effect of motor subtypes of delirium in the intensive care unit on fast-track failure after cardiac surgery | Lee, A. Mu, J. L. Chiu, C. H. Gin, T. Underwood, M. J. Joynt, G. M. | J Thorac Cardiovasc Surg | 2018 |
cardiac surgical procedures |
|
| Preoperative medication use and its association with postoperative length of hospital stay in surgical oncology patients receiving comprehensive geriatric assessment. | Jeong, Y. M. Lee, K. E. Lee, E. S. Kim, K. I. Chung, J. E. Lee, B. K. Gwak, H. S. | Geriatrics & Gerontology International | 2018 |
comprehensive geriatric assessment |
|
| Postoperative Delirium in Cardiac Surgery Patients. | Järvelä, K. Porkkala, H. Karlsson, S. Martikainen, T. Selander, T. Bendel, S. | Journal of Cardiothoracic and Vascular Anesthesia | 2018 |
aged |
|
| “Eight Days of Nightmares … ” – Octogenarian Patients’ Experiences of Postoperative Delirium after Transcatheter or Surgical Aortic Valve Replacement. | Instenes, I. Gjengedal, E. Eide, L. S. P. Kuiper, K. K. J. Ranhoff, A. H. Norekvål, T. M. | Heart Lung and Circulation | 2018 |
aged |
|
| General Anesthesia for Transcatheter Aortic Valve Replacement: Total Intravenous Anesthesia is Associated with Less Delirium as Compared to Volatile Agent Technique. | Goins, A. E. Smeltz, A. Ramm, C. Strassle, P. D. Teeter, E. G. Vavalle, J. P. Kolarczyk, L. | Journal of Cardiothoracic and Vascular Anesthesia | 2018 |
adult |
|
| The use of point-of-care ultrasound to diagnose patent foramen ovale in elective hip and knee arthroplasty patients and its association with postoperative delirium. | Gai, N. Lavi, R. Jones, P. M. Lee, H. Naudie, D. Bainbridge, D. | Can J Anaesth | 2018 | ||
| Comparison of Lurasidone Versus Quetiapine for the Treatment of Delirium in Critically Ill Patients. | Fox, M. A. Elefritz, J. L. Huang, B. M. Hunley, C. | J Intensive Care Med | 2018 |
atypical antipsychotic |
|
| Key components of the delirium syndrome and mortality: greater impact of acute change and disorganised thinking in a prospective cohort study. | Diwell, R. A. Davis, D. H. Vickerstaff, V. Sampson, E. L. | BMC Geriatr | 2018 |
*delirium |
|
| Postoperative Delirium in Indian Patients Following Major Abdominal Surgery for Cancer: Risk Factors and Associations. | Dhakharia, V. Sinha, S. Bhaumik, J. | Indian J Surg Oncol | 2017 |
Cancer |
|
| Effect of an interactive E-learning tool for delirium on patient and nursing outcomes in a geriatric hospital setting: findings of a before-after study. | Detroyer, E. Dobbels, F. Teodorczuk, A. Deschodt, M. Depaifve, Y. Joosten, E. Milisen, K. | BMC Geriatr | 2018 |
*Delirium |
|
| Melatonin and the Prevention and Management of Delirium: A Scoping Study. | Choy, S. W. Yeoh, A. C. Lee, Z. Z. Srikanth, V. Moran, C. | Front Med | 2017 |
delirium |
|
| The impact of sepsis, delirium, and psychological distress on self-rated cognitive function in ICU survivors-a prospective cohort study. | Bruck, E. Schandl, A. Bottai, M. Sackey, P. | J Intensive Care | 2018 |
Anxiety |
|
| Falls and Delirium in an Acute Care Setting: A Retrospective Chart Review Before and After an Organization Wide Interprofessional Education. | Babine, R. L. Hyrkas, K. E. Hallen, S. Wierman, H. R. Bachand, D. A. Chapman, J. L. Fuller, V. J. | J Clin Nurs | 2018 |
delirium |
|
| Prognostic effects of delirium motor subtypes in hospitalized older adults: A prospective cohort study. | Avelino-Silva, T. J. Campora, F. Curiati, J. A. E. Jacob-Filho, W. | PLoS One | 2018 | ||
| Recognition of Delirium Features in Clinical Practice: Data from the "Delirium Day 2015" National Survey. | Mossello, E. Tesi, F. Di Santo, S. G. Mazzone, A. Torrini, M. Cherubini, A. Bo, M. Musicco, M. Bianchetti, A. Ferrari, A. Ferrara, N. Trabucchi, M. Morandi, A. Bellelli, G. | J Am Geriatr Soc | 2017 |
arousal |
|
| A Pilot Analysis of the Association Between Types of Monitored Anesthesia Care Drugs and Outcomes in Transfemoral Aortic Valve Replacement Performed Without General Anesthesia. | Chen, E. Y. Sukumar, N. Dai, F. Akhtar, S. Schonberger, R. B. | Journal of Cardiothoracic and Vascular Anesthesia | 2017 |
age |
|
| Dexmedetomidine Based Sedation for Post-surgery Critically Ill Adults: A Meta-analysis of Randomized Controlled Trials. | Fan, H. Zhao, Y. Sun, M. Ye, J. H. Chen, G. D. Zhu, J. H. | Iran J Public Health | 2017 |
Delirium |
|
| Delirium and mental health history as predictors of aggression in individuals with dementia in inpatient settings. | Wharton T, Paulson D, Macri L, Dubin L | Aging & mental health | 2016 |
Mental Health |
|
| Development and Validation of an Abbreviated Questionnaire to Easily Measure Cognitive Failure in ICU Survivors: A Multicenter Study. | Wassenaar, Annelies De Reus, Jorn Donders, A. Rogier T. Schoonhoven, Lisette Cremer, Olaf L. De Lange, Dylan W. Van Dijk, Diederik Slooter, Arjen J. C. Pickkers, Peter Van Den Boogaard, Mark | Crit Care Med | 2018 |
Psychometrics — Statistics and Numerical Data |
|
| Practice Patterns and Outcomes Associated With Early Sedation Depth in Mechanically Ventilated Patients: A Systematic Review and Meta-Analysis. | Stephens, R. J. Dettmer, M. R. Roberts, B. W. Ablordeppey, E. Fowler, S. A. Kollef, M. H. Fuller, B. M. | Crit Care Med | 2017 | ||
| Nursing assessment as an effective tool for the identification of delirium risk in older in-patients: a case-control study. | Solà-Miravete E, López C, Martínez-Segura E, Adell-Lleixà M, Juvé-Udina ME, Lleixà-Fortuño M | Journal of clinical nursing | 2017 |
delirium |
|
| Implementing ACOVE quality indicators as an intervention checklist to improve care for hospitalized older adults. | Sinvani, L. Kozikowski, A. Smilios, C. Patel, V. Qiu, G. Akerman, M. Lesser, M. Rosenberg, D. Wolf-Klein, G. Pekmezaris, R. | Journal of Hospital Medicine | 2017 |
indwelling catheter |
|
| Health and social factors associated with a delayed discharge amongst inpatients in acute geriatric wards: A retrospective observational study. | Moore, G. Hartley, P. Romero-Ortuno, R. | Geriatrics & Gerontology International | 2017 |
frail older adults |
|
| Impact of restarting home neuropsychiatric medications on sedation outcomes in medical intensive care unit patients | La, M. K. Thompson Bastin, M. L. Gisewhite, J. T. Johnson, C. A. Flannery, A. H. | Journal of Critical Care | 2018 |
amfebutamone |
|
| Exposure to anticholinergic and sedative medicines as indicators of high-risk prescriptions in the elderly. | Jean-Bart, E. Moutet, C. Dauphinot, V. Krolak-Salmon, P. Mouchoux, C. | International Journal of Clinical Pharmacy | 2017 |
NCT01483456 |
|
| Delirium in hemodialysis predicts mortality: a single-center, long-term observational study. | Yasui-Furukori, N. Tarakita, N. Uematsu, W. Saito, H. Nakamura, K. Ohyama, C. Sugawara, N. | Neuropsychiatr Dis Treat | 2017 |
delirium |
|
| The prevention of delirium in elderly with obstructive sleep apnea (PODESA) study: protocol for a multi-centre prospective randomized, controlled trial. | Wong, Jean Lam, David Choi, Stephen Singh, Mandeep Siddiqui, Naveed Sockalingam, Sanjeev Chung, Frances | BMC Anesthesiology | 2018 |
Delirium — Prevention and Control — In Old Age |
|
| Using simulated family presence to decrease agitation in older hospitalized delirious patients: A randomized controlled trial. | Waszynski, Christine M. Milner, Kerry A. Staff, Ilene Molony, Sheila L. | International Journal of Nursing Studies | 2018 |
Dementia |
|
| DemDel, a nursing-led practice-based delirium intervention, improves certain outcomes for older cognitively impaired inpatients. | Wand, A. P. Teodorczuk, A. | Evidence-based nursing | 2017 |
delirium |
|
| Delirium Severity Post-Surgery and its Relationship with Long-Term Cognitive Decline in a Cohort of Patients without Dementia. | Vasunilashorn, S. M. Fong, T. G. Albuquerque, A. Marcantonio, E. R. Schmitt, E. M. Tommet, D. Gou, Y. Travison, T. G. Jones, R. N. Inouye, S. K. | Journal of Alzheimer's Disease | 2017 |
aged |
|
| Turning education into action: Impact of a collective social education approach to improve nurses' ability to recognize and accurately assess delirium in hospitalized older patients. | Travers, C. Henderson, A. Graham, F. Beattie, E. | Nurse Educ Today | 2017 |
Delirium |
|
| Reduced level of arousal and increased mortality in adult acute medical admissions: a systematic review and meta-analysis. | Todd, A. Blackley, S. Burton, J. K. Stott, D. J. Ely, E. W. Tieges, Z. MacLullich, A. M. J. Shenkin, S. D. | BMC Geriatr | 2017 |
Altered mental status |
|
| Risk factors and outcomes of critically ill patients with acute brain failure: A novel end point. | Singh, T. D. O'Horo, J. C. Gajic, O. Sakusic, A. Day, C. N. Mandrekar, J. Kashyap, R. Reddy, D. R. S. Rabinstein, A. A. | Journal of Critical Care | 2018 |
acute brain failure |
|
| Intraoperative oxygen concentration and neurocognition after cardiac surgery: study protocol for a randomized controlled trial. | Shaefi, S. Marcantonio, E. R. Mueller, A. Banner-Goodspeed, V. Robson, S. C. Spear, K. Otterbein, L. E. O'Gara, B. P. Talmor, D. S. Subramaniam, B. | Trials | 2017 |
Cardiac surgery |
|
| A novel scoring system to predict delirium and its relationship with the clinical course in patients with acute decompensated heart failure. | Sakaguchi, T. Watanabe, M. Kawasaki, C. Kuroda, I. Abe, H. Date, M. Ueda, Y. Yasumura, Y. Koretsune, Y. | J Cardiol | 2017 |
Acute heart failure |
|
| Feasibility of a Nurse-Managed Pain, Agitation, and Delirium Protocol in the Surgical Intensive Care Unit. | Rozycki, A. Jarrell, A. S. Kruer, R. M. Young, S. Mendez-Tellez, P. A. | Crit Care Nurse | 2017 | ||
| Development of core outcome sets for effectiveness trials of interventions to prevent and/or treat delirium (Del-COrS): Study protocol. | Rose, L. Agar, M. Burry, L. D. Campbell, N. Clarke, M. Lee, J. Siddiqi, N. Page, V. J. | BMJ Open | 2017 |
article |
|
| The association of geriatric syndromes with hospital outcomes. | Romero-Ortuno, R. Forsyth, D. R. Wilson, K. J. Cameron, E. Wallis, S. Biram, R. Keevil, V. | Journal of Hospital Medicine | 2017 |
acute confusion |
|
| Bright light and oxygen therapies decrease delirium risk in critically ill surgical patients by targeting sleep and acid-base disturbances. | Potharajaroen, S. Tangwongchai, S. Tayjasanant, T. Thawitsri, T. Anderson, G. Maes, M. | Psychiatry Res | 2017 |
Bicarbonate |
|
| Impact of delirium on postoperative frailty and long term cardiovascular events after cardiac surgery. | Ogawa, M. Izawa, K. P. Satomi-Kobayashi, S. Tsuboi, Y. Komaki, K. Gotake, Y. Sakai, Y. Tanaka, H. Okita, Y. | PLoS One | 2017 |
|
|
| The correlation of the depth of anesthesia and postoperative cognitive impairment: A meta-analysis based on randomized controlled trials. | Lu, X. Jin, X. Yang, S. Xia, Y. | J Clin Anesth | 2017 |
Anesthesia |
|
| Geriatric Delirium Care: Using Chart Audits to Target Improvement Strategies. | Loftus, C. A. Wiesenfeld, L. A. | American Journal of Therapeutics | 2017 |
acute care |
|
| Preoperative medication use and postoperative delirium: a systematic review. | Kassie, G. M. Nguyen, T. A. Kalisch Ellett, L. M. Pratt, N. L. Roughead, E. E. | BMC Geriatr | 2017 |
Adverse drug event |
|
| Noise and light pollution in the hospital: A call for action. | Kamdar, B. B. Martin, J. L. Needham, D. M. | Journal of Hospital Medicine | 2017 |
circadian rhythm |
|
| Hydroxyethyl starch is associated with early postoperative delirium in patients undergoing esophagectomy. | Jung, D. M. Ahn, H. J. Yang, M. Kim, J. A. Kim, D. K. Lee, S. M. Park, J. H. | J Thorac Cardiovasc Surg | 2017 |
delirium |
|
| Earplugs could be an effective sleep hygiene strategy to reduce delirium in the ICU. | Hill, L. | Evidence-based nursing | 2017 |
delirium |
|
| Screening and detection of delirium in older ED patients: performance of the modified Confusion Assessment Method for the Emergency Department (mCAM-ED). A two-step tool. | Hasemann, W. Grossmann, F. F. Stadler, R. Bingisser, R. Breil, D. Hafner, M. Kressig, R. W. Nickel, C. H. | Intern Emerg Med | 2017 |
Algorithms |
|
| PERFECTED enhanced recovery (PERFECT-ER) care versus standard acute care for patients admitted to acute settings with hip fracture identified as experiencing confusion: study protocol for a feasibility cluster randomized controlled trial. | Hammond, S. P. Cross, J. L. Shepstone, L. Backhouse, T. Henderson, C. Poland, F. Sims, E. MacLullich, A. Penhale, B. Howard, R. Lambert, N. Varley, A. Smith, T. O. Sahota, O. Donell, S. Patel, M. Ballard, C. Young, J. Knapp, M. Jackson, S. Waring, J. Leav | Trials | 2017 |
Acute care |
|
| Improving the Accuracy of Delirium Assessments in Neuroscience Patients: Scaling a Quality Improvement Program to Improve Nurses' Skill, Compliance, and Accuracy in the Use of the Confusion Assessment Method in the Intensive Care Unit Tool. | DiLibero, Justin | Dimensions of Critical Care Nursing | 2018 |
Delirium — Evaluation |
|
| Attention, vigilance, and visuospatial function in hospitalized elderly medical patients: relationship to delirium syndromal status and motor subtype profile. | Daly, C. Leonard, M. O'Connell, H. Williams, O. Awan, F. Exton, C. O'Connor, M. Adamis, D. Dunne, C. P. Cullen, W. Meagher, D. J. | Int Psychogeriatr | 2017 |
assessment |
|
| Caring for a patient with delirium in an acute hospital: The lived experience of cardiology, elderly care, renal, and respiratory nurses. | Brooke, J. Manneh, C. | Int J Nurs Pract | 2018 |
aggression |
|
| Association between Delirium and Prehospitalization Medication in Poststroke Patients. | Hosoya, R. Sato, Y. Ishida, E. Shibamoto, H. Hino, S. Yokote, H. Kamata, T. | J Stroke Cerebrovasc Dis | 2018 |
Derilium |
|
| Acute Brain Dysfunction: Development and Validation of a Daily Prediction Model. | Marra, A. Pandharipande, P. P. Shotwell, M. S. Chandrasekhar, R. Girard, T. D. Shintani, A. K. Peelen, L. M. Moons, K. Dittus, R. S. Ely, E. W. Vasilevskis, E. E. | Chest | 2018 |
Coma |
|
| Delirium in the Elderly. | Hshieh, T. T. Inouye, S. K. Oh, E. S. | Psychiatr Clin North Am | 2018 |
Cognitive decline |
|
| Barriers to delirium assessment in the intensive care unit: A literature review. | Rowley-Conwy, G. | Intensive Crit Care Nurs | 2018 |
Critical Care Nursing/*methods |
|
| Exploratory and Confirmatory Factor Analyses of Delirium Symptoms in a Sample of Nursing Home Residents. | Moyo P, Huang TY, Simoni-Wastila L, Harrington D | Journal of applied gerontology : the official journal of the Southern Gerontological Society | 2016 |
confirmatory factor analysis |
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| Neurosurgery in Octogenarians: A Prospective Study of Perioperative Morbidity, Mortality, and Complications in Elderly Patients. | Maldaner, N. Sarnthein, J. Bozinov, O. Regli, L. Neidert, M. C. | World Neurosurgery | 2018 |
glucocorticoid |
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| Delirium in the Cardiac Intensive Care Unit. | Ibrahim, K. McCarthy, C. P. McCarthy, K. J. Brown, C. H. Needham, D. M. Januzzi, J. L., Jr. McEvoy, J. W. | J Am Heart Assoc | 2018 |
critical care |
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| The Diagnostic Sensitivity of the Memorial Delirium Assessment Scale—Spanish Version | Barahona, E. Pinhao, R. Galindo, V. Noguera, A. | Journal of Pain and Symptom Management | 2018 |
adult |
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| First- and second-line pharmacological treatment for delirium in general hospital setting-Retrospective analysis. | Wada, K. Morita, Y. Iwamoto, T. Mifune, Y. Nojima, S. | Asian J Psychiatr | 2018 |
Consultation liaison service |
|
| Increasing use of cognitive measures in the operational definition of frailty-A systematic review | Vella Azzopardi, R. Beyer, I. Vermeiren, S. Petrovic, M. Van Den Noortgate, N. Bautmans, I. Gorus, E. | Ageing Res Rev | 2018 |
Aged |
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| Preoperative Hemoglobin Level is Associated with Increased Health Care Use After Elective Spinal Fusion (≥3 Levels) in Elderly Male Patients with Spine Deformity. | Elsamadicy, A. A. Adogwa, O. Ongele, M. Sergesketter, A. R. Tarnasky, A. Lubkin, D. E. T. Drysdale, N. Cheng, J. Bagley, C. A. Karikari, I. O. | World Neurosurg | 2018 |
aged |
|
| Comprehensive geriatric assessment for older people admitted to a surgical service. | Eamer, G. Taheri, A. Chen, S. S. Daviduck, Q. Chambers, T. Shi, X. Khadaroo, R. G. | Cochrane Database of Systematic Reviews | 2018 |
clinical assessment |
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| Effects of a Medication Review on Delirium in Older Hospitalised Patients: A Comparative Retrospective Cohort Study. | van Velthuijsen, E. L. Zwakhalen, S. M. G. Pijpers, E. van de Ven, L. I. Ambergen, T. Mulder, W. J. Verhey, F. R. J. Kempen, Gijm | Drugs Aging | 2018 | ||
| Effect of haloperidol on survival among critically ill adults with a high risk of delirium the REDUCE randomized clinical trial | Van Den Boogaard, M. Slooter, A. J. C. Brüggemann, R. J. M. Schoonhoven, L. Beishuizen, A. Vermeijden, J. W. Pretorius, D. De Koning, J. Simons, K. S. Dennesen, P. J. W. Van Der Voort, P. H. J. Houterman, S. Van Der Hoeven, J. G. Pickkers, P. | JAMA | 2018 |
adult |
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| Individualized Acute Medical Care for Cognitively Impaired Individuals: A Call Always to Pause Before Hospitalization. | Sheckter, C. C. Bott, N. T. Milstein, A. Leff, B. | J Am Geriatr Soc | 2018 |
cognitive defect |
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| Baden Prevention and Reduction of Incidence of Postoperative Delirium Trial (PRIDe): a phase IV multicenter, randomized, placebo-controlled, double-blind clinical trial of ketamine versus haloperidol for prevention of postoperative delirium. | Riegger, H. Hollinger, A. Seifert, B. Toft, K. Blum, A. Zehnder, T. Siegemund, M. | Trials | 2018 |
Dos |
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| Frequency and predictors of post-stroke delirium in PRospective Observational POLIsh Study (PROPOLIS) | Pasinska, P. Kowalska, K. Klimiec, E. Szyper-Maciejowska, A. Wilk, A. Klimkowicz-Mrowiec, A. | J Neurol | 2018 |
Delirium |
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| Hypertension, mitral valve disease, atrial fibrillation and low education level predict delirium and worst outcome after cardiac surgery in older adults. | Oliveira, F. R. Oliveira, V. H. Oliveira, I. M. Lima, J. W. Calderaro, D. Gualandro, D. M. Caramelli, B. | BMC Anesthesiology | 2018 |
*Cardiac surgery |
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| Delirium, Frailty, and Fast-Track Surgery in Oncogeriatrics: Is There a Link? | Monacelli, F. Signori, A. Prefumo, M. Giannotti, C. Nencioni, A. Romairone, E. Scabini, S. Odetti, P. | Dementia and Geriatric Cognitive Disorders Extra | 2018 |
aged |
|
| Confusion Strongly Associated with Antibiotic Prescribing Due to Suspected Urinary Tract Infections in Nursing Homes. | Mayne, S. Sundvall, P. D. Gunnarsson, R. | J Am Geriatr Soc | 2018 |
urinary catheter |