Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Neural autoantibodies in delirium
Authors
Hansen, N. Krasiuk, I. Titsch, T.
Year
2021
Journal
J Autoimmun
Abstract

BACKGROUND: Delirium in hospitalized and intensive care unit patients is an emerging condition due to its rapid-onset requiring fast action to mitigate a worse clinical outcome. Although several causes and conditions are known, the association between delirium and neural autoantibodies has often been neglected in cohort studies and reviews as causing delirium. The aim of our review is to delineate the occurrence and type of neural autoantibodies and to depict other biological markers of autoimmunity in relationship to delirium. METHODS: For this narrative review Pubmed research was done to select articles about delirium and neural autoantibodies. RESULTS: We can report on several cell-surface autoantibodies such as anti-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors, anti-contactin associated protein 2, anti-Leucin rich glioma inactivated protein 1, anti-dipeptidyl-peptidase-like 6 protein, anti-glycine receptor and anti-myelin autoantibodies, as well as intracellular autoantibodies such as anti-glutamic acid decarboxylase 65 (GAD65), anti-CV2 and anti-Hu associated with delirium in patients. Our case reports and case series screening revealed that 20 of 63 patients with delirium presented neural autoantibodies, thus revealing a 32% frequency of autoantibody-associated delirium in delirium patients. Our main finding is that delirium’s hyperactive form is associated with neural autoantibodies. Diagnosing delirium differentially is difficult, as in patients with delirium and GAD65 autoantibodies, as it must be distinguished from other psychopathological excitation states such as mania. We also describe autoimmune delirium’s potential pathophysiologic pathways. CONCLUSIONS: The existence of neural autoantibodies in delirious patients is scientifically and clinically highly relevant in its diagnosis, therapy, and pathogenesis. More large-scale studies should be conducted to evaluate their significance and prevalence in delirium.

PMID

34757245

Keywords

Cognitive dysfunction
Delirium
Neural autoantibody
Postoperative delirium

Page(s)
Issue

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Total Records Found: 6272, showing 100 per page
TitleAuthorsJournalYearKeywords
Validating the 4A's test in screening for delirium in a culturally diverse geriatric inpatient population. De, J. Wand, A. P. F. Smerdely, P. I. Hunt, G. E. Int J Geriatr Psychiatry 2017

delirium screening
dementia
diagnostic accuracy
geriatrics
non-English speaking
validation

Delirium, frailty and mortality: interactions in a prospective study of hospitalized older people. Dani, M. Owen, L. H. Jackson, T. A. Rockwood, K. Sampson, E. L. Davis, D. J Gerontol A Biol Sci Med Sci 2017

Outcomes
longevity
risk factors

Impact of inhalational versus intravenous anaesthesia on early delirium and long-term survival in elderly patients after cancer surgery: study protocol of a multicentre, open-label, and randomised controlled trial. Zhang, Y. Li, H. J. Wang, D. X. Jia, H. Q. Sun, X. D. Pan, L. H. Ye, Q. S. Ouyang, W. Jia, Z. Zhang, F. X. Guo, Y. Q. Ai, Y. Q. Zhao, B. J. Yang, X. D. Zhang, Q. G. Yin, N. Tan, H. Y. Liu, Z. H. Yu, J. B. Ma, D. BMJ Open 2017

anaesthesia in oncology
cancer
surgery
survival

Hypertonic saline for prevention of delirium in geriatric patients who underwent hip surgery. Xin, X. Xin, F. Chen, X. Zhang, Q. Li, Y. Huo, S. Chang, C. Wang, Q. J Neuroinflammation 2017

Cytokines
Elderly
Hypertonic saline
Monocytes
Neuroinflammation
Postoperative delirium

Delirium and Catatonia in Critically Ill Patients: The Delirium and Catatonia Prospective Cohort Investigation. Wilson, J. E. Carlson, R. Duggan, M. C. Pandharipande, P. Girard, T. D. Wang, L. Thompson, J. L. Chandrasekhar, R. Francis, A. Nicolson, S. E. Dittus, R. S. Heckers, S. Ely, E. W. Crit Care Med 2017

Aged
Catatonia/*diagnosis/*epidemiology
*Critical Illness
Delirium/*diagnostic imaging/*epidemiology
Female
Humans
Intensive Care Units/statistics & numerical data
Male
Middle Aged
Prospective Studies
Reproducibility of Results
Respiration, Artificial/methods
Severity of Illness Index
Vasoconstrictor Agents/administration & dosage

Ketamine for the acute management of excited delirium and agitation in the prehospital setting. Weant, K. A. Linder, L. M. Ross, C. A. Pharmacotherapy 2017

Agitation
Ketamine
emergency medicine
excited delirium
prehospital

Improved detection of delirium, implementation and validation of the CAM-ICU in elderly Emergency Department patients. Van de Meeberg EK, Festen S, Kwant M, Georg RR, Izaks GJ, Ter Maaten JC European journal of emergency medicine : official journal of the European Society for Emergency Medicine 2016
Delirium symptoms are associated with decline in cognitive function between ages 53 and 69 years: Findings from a British birth cohort study. Tsui, A. Kuh, D. Richards, M. Davis, D. Alzheimers Dement 2017

Cognitive decline
Delirium
Dementia
Life course

Delirium is associated with increased mortality in the geriatric population. Tosun Tasar, P. Sahin, S. Akcam, N. O. Dinckal, C. Ulusoy, M. G. Sarikaya, O. F. Duman, S. Akcicek, F. Noyan, A. Int J Psychiatry Clin Pract 2017

Delirium
elderly
mortality

Disturbances in Oxygen Balance During Cardiopulmonary Bypass: A Risk Factor for Postoperative Delirium. Smulter, N. Lingehall, H. C. Gustafson, Y. Olofsson, B. Engström, K. G. Appelblad, M. Svenmarker, S. J Cardiothorac Vasc Anesth 2017

aged
body surface
body weight
cardiopulmonary bypass
diagnosis
DSM-IV-TR
female
fluid balance
heart center
heart surgery
human
major clinical study
male
Mini Mental State Examination
observational study
organic brain syndrome
oxygen saturation
postoperative delirium
prospective study
risk assessment
risk factor
surgery
university hospital
vein
oxygen

Perceptions of Family Members, Nurses, and Physicians on Involving Patients' Families in Delirium Prevention. Smithburger, P. L. Korenoski, A. S. Kane-Gill, S. L. Alexander, S. A. Crit Care Nurse 2017
Perceptions of Families of Intensive Care Unit Patients Regarding Involvement in Delirium-Prevention Activities: A Qualitative Study. Smithburger, P. L. Korenoski, A. S. Alexander, S. A. Kane-Gill, S. L. Crit Care Nurse 2017
A Predictive Model of the Prevalence of Delirium in Elderly Subjects Admitted to Nursing Homes. Perez-Ros, P. Martinez-Arnau, F. M. Baixauli-Alacreu, S. Garcia-Gollarte, J. F. Tarazona-Santabalbina, F. Endocr Metab Immune Disord Drug Targets 2017

Delirium
nursing homes
older adults
patient safety
prevalence
risk factors

Incidence and Risk Factors for Postoperative Delirium in Patients After Hepatectomy. Park SA, Tomimaru Y, Shibata A, Miyagawa S, Noguchi K, Dono K World journal of surgery 2017
Five short screening tests in the detection of prevalent delirium: diagnostic accuracy and performance in different neurocognitive subgroups. O'Regan, N. A. Maughan, K. Liddy, N. Fitzgerald, J. Adamis, D. Molloy, D. W. Meagher, D. Timmons, S. Int J Geriatr Psychiatry 2017

cognition
delirium
diagnosis
evaluation studies
sensitivity and specificity

Midterm outcomes after postoperative delirium on cognition and mood in patients after cardiac surgery. Nguyen, Q. Uminski, K. Hiebert, B. M. Tangri, N. Arora, R. C. Journal of Thoracic and Cardiovascular Surgery 2017

adult
Alcohol Use Disorders Identification Test
anxiety
cognition
cohort analysis
comorbidity
coronary artery bypass graft
diagnosis
female
follow up
heart valve replacement
hospitalization
human
intensive care unit
major clinical study
male
memory disorder
Montreal cognitive assessment
mood disorder
Patient Health Questionnaire 9
postoperative delirium
postoperative period
prospective study
surgery
telephone interview

The delirium drug scale is associated to delirium incidence in the emergency department. Nguyen, Patrick Viet-Quoc Pelletier, Lucie Payot, Isabelle Latour, Judith International Psychogeriatrics 2017

delirium
aged
anticholinergic agents
emergency department
2017

Post-operative delirium is associated with increased 5-year mortality. Moskowitz, E. E. Overbey, D. M. Jones, T. S. Jones, E. L. Arcomano, T. R. Moore, J. T. Robinson, T. N. Am J Surg 2017

Aged
Colorado
Delirium/epidemiology/*mortality
Female
Humans
Incidence
Male
Middle Aged
Postoperative Complications/epidemiology/*mortality
Prospective Studies
Risk Factors
Treatment Outcome
Acute brain syndrome
Cognitive dysfunction
Confusion
Frailty
Geriatric

Worldwide Survey of the "Assessing Pain, Both Spontaneous Awakening and Breathing Trials, Choice of Drugs, Delirium Monitoring/Management, Early Exercise/Mobility, and Family Empowerment" (ABCDEF) Bundle. Morandi, A. Piva, S. Ely, E. W. Myatra, S. N. Salluh, J. I. F. Amare, D. Azoulay, E. Bellelli, G. Csomos, A. Fan, E. Fagoni, N. Girard, T. D. Heras La Calle, G. Inoue, S. Lim, C. M. Kaps, R. Kotfis, K. Koh, Y. Misango, D. Pandharipande, P. P. Permpikul, C Crit Care Med 2017

Adult
Aged
Cross-Sectional Studies
Delirium/diagnosis/therapy
Early Ambulation/statistics & numerical data
Family
Humans
Intensive Care Units/*statistics & numerical data
*Knowledge
Medicine/statistics & numerical data
Middle Aged
Pain Management
Pain Measurement
Patient Care Bundles/*methods/*utilization
Physicians/*statistics & numerical data
Respiration

Validation of an automated delirium prediction model (DElirium MOdel (DEMO)): an observational study. Mestres Gonzalvo, C. de Wit, Hajm van Oijen, B. P. C. Deben, D. S. Hurkens, Kpgm Mulder, W. J. Janknegt, R. Schols, Jmga Verhey, F. R. Winkens, B. van der Kuy, P. M. BMJ Open 2017

geriatric medicine
psychiatry

Peripheral Nerve Block as a Supplement to Light or Deep General Anesthesia in Elderly Patients Receiving Total Hip Arthroplasty: A Prospective Randomized Study. Mei, B. Zha, H. Lu, X. Cheng, X. Chen, S. Liu, X. Li, Y. Gu, E. Clin J Pain 2017
INTERDEM Academy special section: what effect does delirium have on family and nurses of older adult patients? Martins, S. Pinho, E. Correia, R. Moreira, E. Lopes, L. Paiva, J. A. Azevedo, L. Fernandes, L. Aging Ment Health 2017

Delirium
caregivers
family
nurses
psychological distress

Implementing a Multicomponent Intervention to Prevent Delirium Among Critically Ill Patients. Martinez, F. Donoso, A. M. Marquez, C. Labarca, E. Crit Care Nurse 2017
Health-Care Workers' Judgments About Pain in Older Palliative Care Patients With and Without Delirium. Mah, K. Rodin, R. A. Chan, V. W. S. Stevens, B. J. Zimmermann, C. Gagliese, L. Am J Hosp Palliat Care 2017

cancer pain
chart audit
delirium
older people
pain management
palliative care

Incidence and Risk Factors of Delirium in Patients After Type-A Aortic Dissection Surgery. Liu, Z. Pang, X. Zhang, X. Cao, G. Fang, C. Wu, S. J Cardiothorac Vasc Anesth 2017

delirium
incidence
risk factors
type-A aortic dissection

Comparison of regional with general anaesthesia on postoperative delirium (RAGA-delirium) in the older patients undergoing hip fracture surgery: Study protocol for a multicentre randomised controlled trial. Li, T. Yeung, J. Li, J. Zhang, Y. Melody, T. Gao, Y. Wang, Y. Lian, Q. Gao, F. BMJ Open 2017

NCT02213380
etomidate
fentanyl
isoflurane
local anesthetic agent
nitrous oxide
propofol
sevoflurane
sufentanil
adult
aged
article
China
controlled study
cost effectiveness analysis
epidural anesthesia
general anesthesia
health care cost
hip fracture
hospitalization
human
intermethod comparison
major clinical study
multicenter study
outcome assessment
pain
pain assessment
postoperative delirium
prospective study
quality of life
randomized controlled trial
regional anesthesia
spinal anesthesia

Factors Related to the Severity of Delirium in the Elderly Patients With Infection. Kuswardhani, R. A. T. Sugi, Y. S. Gerontol Geriatr Med 2017

delirium
elderly
infection

Decreasing Delirium through Music (DDM) in critically ill, mechanically ventilated patients in the intensive care unit: study protocol for a pilot randomized controlled trial. Khan, S. H. Wang, S. Harrawood, A. Martinez, S. Heiderscheit, A. Chlan, L. Perkins, A. J. Tu, W. Boustani, M. Khan, B. Trials 2017

Critical care
Delirium
Music

Sinai Abbreviated Geriatric Evaluation: Development and Validation of a Practical Test. Katlic, M. R. Coleman, J. Khan, K. Wozniak, S. E. Abraham, J. H. Ann Surg 2017
Structured interdisciplinary bedside rounds do not reduce length of hospital stay and 28-day re-admission rate among older people hospitalised with acute illness: an Australian study. Huynh, E. Basic, D. Gonzales, R. Shanley, C. Aust Health Rev 2017
Cerebrospinal Fluid S100B and Alzheimer’s Disease Biomarkers in Hip Fracture Patients with Delirium. Hov, K. R. Bolstad, N. Idland, A. V. Zetterberg, H. Blennow, K. Chaudhry, F. A. Frihagen, F. Ræder, J. Wyller, T. B. Watne, L. O. Dementia and Geriatric Cognitive Disorders Extra 2017

adult
Alzheimer disease
astrocyte
cerebrospinal fluid
cohort analysis
consensus
delirium
diagnosis
elective surgery
electrochemiluminescence
enzyme linked immunosorbent assay
female
hip fracture
human
major clinical study
male
pathology
prospective study
spinal anesthesia
university hospital
biological marker
endogenous compound
protein S100B
tau protein

Effect of various antipsychotic regimens on incidence of delirium in critically ill adults. Hawkins, W. A. Phan, S. V. Campbell, S. L. J Crit Care 2017

Antipsychotic agents
Critical illness
Delirium
Intensive care units
Prevention

2-(18)F-fluoro-2-deoxyglucose positron emission tomography in delirium. Haggstrom, L. R. Nelson, J. A. Wegner, E. A. Caplan, G. A. J Cereb Blood Flow Metab 2017

Aged
Aged, 80 and over
Attention
Delirium/*diagnostic imaging/metabolism
Female
*Fluorodeoxyglucose F18
Glucose/metabolism
Gyrus Cinguli/diagnostic imaging/metabolism
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging
Male
Neuropsychological Tests
Positron-Emission Tomography/*methods
Prospective Studies
*Radiopharmaceuticals
Fluorodeoxyglucose F18
cerebral metabolism
delirium
functional neuroimaging
positron emission tomography

Preoperative Serum Metabolites Are Associated With Postoperative Delirium in Elderly Hip-Fracture Patients. Guo, Y. Zhang, Y. Jia, P. Wang, W. Zhou, Q. Sun, L. Zhao, A. Zhang, X. Wang, X. Li, Y. Zhang, J. Jiang, W. J Gerontol A Biol Sci Med Sci 2017

Aged
Delirium/*epidemiology
Female
Hip Fractures/*blood/*surgery
Humans
Male
*Metabolomics
Postoperative Complications/*epidemiology
Preoperative Period
Elderly patients
Hip fracture
Metabolomics
Postoperative delirium
Risk metabolites

Delirium and effect of circadian light in the intensive care unit: a retrospective cohort study. Estrup, S. Kjer, C. K. W. Poulsen, L. M. Gogenur, I. Mathiesen, O. Acta Anaesthesiol Scand 2017
Advance Directives, Hospitalization, and Survival Among Advanced Cancer Patients with Delirium Presenting to the Emergency Department: A Prospective Study. Elsayem, A. F. Bruera, E. Valentine, A. Warneke, C. L. Wood, G. L. Yeung, S. J. Page, V. D. Silvestre, J. Brock, P. A. Todd, K. H. Oncologist 2017

Advance directives
Cancer
Delirium
Emergency
Survival

Post-operative delirium is an independent predictor of 30-day hospital readmission after spine surgery in the elderly (≥65 years old): A study of 453 consecutive elderly spine surgery patients. Elsamadicy, A. A. Wang, T. Y. Back, A. G. Lydon, E. Reddy, G. B. Karikari, I. O. Gottfried, O. N. Journal of Clinical Neuroscience 2017

acute kidney failure
aged
aging
article
cardiopulmonary arrest
deep vein thrombosis
female
heart infarction
hospital readmission
human
length of stay
lung embolism
major clinical study
male
pneumonia
postoperative delirium
priority journal
retrospective study
risk assessment
risk factor
sepsis
spine surgery
surgical infection
urinary tract infection

The Abbreviated Mental Test 4 for cognitive screening of older adults presenting to the Emergency Department. Dyer, A. H. Briggs, R. Nabeel, S. O'Neill, D. Kennelly, S. P. Eur J Emerg Med 2017
A Proactive Approach to High Risk Delirium Patients Undergoing Total Joint Arthroplasty. Duque, A. F. Post, Z. D. Orozco, F. R. Lutz, R. W. Ong, A. C. J Arthroplasty 2017

complications
delirium
perioperative screening
prevention
total joint arthroplasty

Poor Performance on a Preoperative Cognitive Screening Test Predicts Postoperative Complications in Older Orthopedic Surgical Patients. Culley, D. J. Flaherty, D. Fahey, M. C. Rudolph, J. L. Javedan, H. Huang, C. C. Wright, J. Bader, A. M. Hyman, B. T. Blacker, D. Crosby, G. Anesthesiology 2017

Age Factors
Aged
Aged, 80 and over
Cognition Disorders/diagnosis/psychology
Delirium/*diagnosis/etiology/*psychology
Female
Humans
Length of Stay/trends
Male
Neuropsychological Tests
Orthopedic Procedures/*adverse effects/trends
Postoperative Complications/*diagnosis/etiology/*psychology
Predictive Value of Tests
Preoperative Care/*methods
Prospective Studies

Early postoperative delirium after hemiarthroplasty in elderly patients aged over 70 years with displaced femoral neck fracture. Choi, Y. H. Kim, D. H. Kim, T. Y. Lim, T. W. Kim, S. W. Yoo, J. H. Clin Interv Aging 2017

delirium
elderly patients
femoral neck fracture
hemiarthroplasty

Effect of short-term exposure to ambient air particulate matter on incidence of delirium in a surgical population. Che, L. Li, Y. Gan, C. Sci Rep 2017
Subsyndromal Delirium and Institutionalization Among Patients With Critical Illness. Brummel, N. E. Boehm, L. M. Girard, T. D. Pandharipande, P. P. Jackson, J. C. Hughes, C. G. Patel, M. B. Han, J. H. Vasilevskis, E. E. Thompson, J. L. Chandrasekhar, R. Bernard, G. R. Dittus, R. S. Ely, E. W. Am J Crit Care 2017
Delirium in the intensive care setting: A reevaluation of the validity of the CAM-ICU and ICDSC versus the DSM-IV-TR in determining a diagnosis of delirium as part of the daily clinical routine. Boettger, S. Nunez, D. G. Meyer, R. Richter, A. Fernandez, S. F. Rudiger, A. Schubert, M. Jenewein, J. Palliat Support Care 2017

Concurrent validity
Confusion Assessment Method for Intensive Care Units (CAM-ICU)
Dsm-iv-tr
Delirium
Intensive Care Delirium Screening Checklist (ICDSC)
Intensive care unit

Delirium in the intensive care setting and the Richmond Agitation and Sedation Scale (RASS): Drowsiness increases the risk and is subthreshold for delirium. Boettger, S. Nunez, D. G. Meyer, R. Richter, A. Fernandez, S. F. Rudiger, A. Schubert, M. Jenewein, J. J Psychosom Res 2017

Alertness
Delirium
Delirium Rating Scale-Revised 1998 (DRS-R-98)
Drowsiness
Intensive Care Unit (ICU)
Richmond Agitation and Sedation Scale (RASS)
Symptom profile

Is Delirium the Cognitive Harbinger of Frailty in Older Adults? A Review about the Existing Evidence. Bellelli, G. Moresco, R. Panina-Bordignon, P. Arosio, B. Gelfi, C. Morandi, A. Cesari, M. Front Med 2017

delirium
frailty
geriatric syndromes
older adults
review of literature pathophysiology

Recovery after critical illness: putting the puzzle together-a consensus of 29. Azoulay, Elie Vincent, Jean-Louis Angus, Derek C. Arabi, Yaseen M. Brochard, Laurent Brett, Stephen J. Citerio, Giuseppe Cook, Deborah J. Curtis, Jared Randall dos Santos, Claudia C. Ely, E. Wesley Hall, Jesse Halpern, Scott D. Hart, Nicholas Hopkins, Ram Crit Care 2017
The efficacy of antipsychotics for prolonged delirium with renal dysfunction. Asano, S. Kunii, Y. Hoshino, H. Osakabe, Y. Shiga, T. Itagaki, S. Miura, I. Yabe, H. Neuropsychiatr Dis Treat 2017

antipsychotic
chronic kidney disease
pharmacokinetics
prolonged delirium

Comparison of the effect of high versus low mean arterial pressure levels on clinical outcomes and complications in elderly patients during non-cardiothoracic surgery under general anesthesia: study protocol for a randomized controlled trial. Anmin, Hu Yan, Qiu Peng, Zhang Bailong, Hu Yali, Yang Shutao, Li Rui, Zhao Zhongjun, Zhang Yaoxian, Zhang Zihao, Zheng Chen, Qiu Furong, Li Xiaolei, Gong Hu, Anmin Qiu, Yan Zhang, Peng Hu, Bailong Yang, Yali Li, Shutao Zhao, Rui Trials 2017
Association between baseline cognitive impairment and postoperative delirium in elderly patients undergoing surgery for adult spinal deformity. Adogwa, O. Elsamadicy, A. A. Vuong, V. D. Fialkoff, J. Cheng, J. Karikari, I. O. Bagley, C. A. J Neurosurg Spine 2017

CAM = Confusion Assessment Method
MMSE = Mini-Mental State Examination
SLUMS = Saint Louis University Mental Status
SNF = skilled nursing facility
Saint Louis Mental Status test
cognitive impairment
deformity
degenerative scoliosis
delirium
elderly
spine surgery

Effect of the Hospital Elder Life Program on Risk of 30-Day Readmission. Rubin, F. H. Bellon, J. Bilderback, A. Urda, K. Inouye, S. K. Journal of the American Geriatrics Society 2017

aged
cohort analysis
controlled study
delirium
emergency care
female
hospital readmission
human
major clinical study
outpatient department
prospective study
retrospective study
risk assessment
risk factor
staff
surgery
teaching hospital
total quality management

Clinical outcomes in older surgical patients with mild cognitive impairment. Racine, A. M. Fong, T. G. Gou, Y. Travison, T. G. Tommet, D. Erickson, K. Jones, R. N. Dickerson, B. C. Metzger, E. Marcantonio, E. R. Schmitt, E. M. Inouye, S. K. Alzheimers Dement 2017

Mild cognitive impairment
Postoperative
Prodromal Alzheimer’s disease
Surgery
delirium

Prediction of Long-term Cognitive Decline Following Postoperative Delirium in Older Adults. Devore EE, Fong TG, Marcantonio ER, Schmitt EM, Travison TG, Jones RN, Inouye SK The journals of gerontology. Series A, Biological sciences and medical sciences 2017

Aged
Cognitive Dysfunction/*etiology
Delirium/*complications
Female
Humans
Male
*Postoperative Complications
Prognosis
Proof of Concept Study
Prospective Studies
Risk Factors
Time Factors
Cognition
Delirium
Elective surgery

The Cognitive Reserve Model in the Development of Delirium: The Successful Aging After Elective Surgery Study. Cizginer, S. Marcantonio, E. Vasunilashorn, S. Pascual-Leone, A. Shafi, M. Schmitt, E. M. Inouye, S. K. Jones, R. N. J Geriatr Psychiatry Neurol 2017

delirium
inflammation
reserve

Incidence of Delirium Among Patients Having Cancer Injected With Different Opioids for the First Time. Tanaka R, Ishikawa H, Sato T, Shino M, Matsumoto T, Mori K, Omae K, Osaka I The American journal of hospice & palliative care 2016

delirium
fentanyl
introduction
morphine
opioid injection drugs
oxycodone

Complications after hip fracture surgery: are they preventable? Flikweert, E. R. Wendt, K. W. Diercks, R. L. Izaks, G. J. Landsheer, D. Stevens, M. Reininga, I. H. F. Eur J Trauma Emerg Surg 2017

Complications
Frail elderly
Hip fracture

Pilot prospective study of post-surgery sleep and EEG predictors of post-operative delirium. Evans, J. L. Nadler, J. W. Preud'homme, X. A. Fang, E. Daughtry, R. L. Chapman, J. B. Attarian, D. Wellman, S. Krystal, A. D. Clin Neurophysiol 2017

Aged
Aged, 80 and over
Delirium/diagnosis/epidemiology/*physiopathology
Electroencephalography/*trends
Female
Humans
Male
Middle Aged
Orthopedic Procedures/adverse effects/trends
Pilot Projects
Postoperative Complications/diagnosis/epidemiology/*physiopathology
Predictive Value of Tests
Prospective Studies
Sleep Initiation and Maintenance
Disorders/diagnosis/epidemiology/*physiopathology
Sleep Stages/*physiology
Delirium
Eeg
Post-operative delirium
Sleep

Development of an international undergraduate curriculum for delirium using a modified delphi process. Copeland, C. Fisher, J. Teodorczuk, A. Age Ageing 2017

curriculum
delirium
education
geriatric medicine teaching
older people
training

Serum galectin-3 levels and delirium among postpartum intensive care unit women. Zhu, Y. Hu, W. Zhu, M. L. Yin, T. Su, J. Wang, J. R. Brain Behav 2017

delirium
galectin-3
intensive care unit
postpartum
women

Characteristics of patients with an unplanned admission to an acute palliative care unit. Mercadante, S. Adile, C. Ferrera, P. Casuccio, A. Intern Emerg Med 2017

Cancer
Early palliative care
Emergency
Symptom control
Unplanned admission

FRAIL Questionnaire Screening Tool and Short-Term Outcomes in Geriatric Fracture Patients. Gleason, L. J. Benton, E. A. Alvarez-Nebreda, M. L. Weaver, M. J. Harris, M. B. Javedan, H. J Am Med Dir Assoc 2017

Frailty
delirium
fall
fracture
older adult

Disruption of the ascending arousal system and cortical attention networks in post-stroke delirium and spatial neglect. Boukrina, O. Barrett, A. M. Neurosci Biobehav Rev 2017

Aras
Ascending arousal system
Ascending reticular activating system
Attention
Basal forebrain
Delirium
Dorsal attention network
Reticular formation
Spatial neglect
Stroke
Thalamus

Incidence of delirium after cardiac surgery: protocol for the DELIRIUM-CS Canada cross-sectional cohort study. DELIRIUM-CS Investigators, Canadian Cardiovascular Critical Care Society Investigator Group and the Canadian Critical Care Trials Group CMAJ Open 2017
Preoperative C-Reactive Protein as a Risk Factor for Postoperative Delirium in Elderly Patients Undergoing Laparoscopic Surgery for Colon Carcinoma. Xiang, Dong Xing, Hailin Tai, Huiyu Xie, Guozhu BioMed Research International 2017
Responding to Ten Common Delirium Misconceptions With Best Evidence: An Educational Review for Clinicians. Oldham, M. A. Flanagan, N. M. Khan, A. Boukrina, O. Marcantonio, E. R. J Neuropsychiatry Clin Neurosci 2017

Cognitive Disorders
Delirium
Dementia
Diagnosis and Classification in Neuropsychiatry
Geriatric Neuropsychiatry

The network model of delirium. Young JWS Medical hypotheses 2017

Default-mode network
Delirium
Dorsal attention network
Frontoparietal control network
Salience network

Aging and Post-Intensive Care Syndrome: A Critical Need for Geriatric Psychiatry. Wang, S. Allen, D. Kheir, Y. N. Campbell, N. Khan, B. Am J Geriatr Psychiatry 2017

Aging
caregiver stress
cognitive impairment
critical care illness
delirium
intensive care unit
post-intensive care syndrome

Intensive care discharge delay is associated with increased hospital length of stay: A multicentre prospective observational study. Tiruvoipati, R. Botha, J. Fletcher, J. Gangopadhyay, H. Majumdar, M. Vij, S. Paul, E. Pilcher, D. PLoS One 2017

Adolescent
Adult
Aged
Aged, 80 and over
Child
Delirium/epidemiology
Female
Humans
Incidence
*Intensive Care Units
*Length of Stay
Male
Middle Aged
*Patient Discharge
Patients’ Rooms
Prospective Studies
Time Factors
Young Adult

How can we identify patients with delirium in the emergency department?: A review of available screening and diagnostic tools. Tamune H, Yasugi D The American journal of emergency medicine 2017

Aged
Delirium/*diagnosis
Dementia/*complications
*Emergency Service, Hospital
Geriatric Assessment/*methods
Humans
Mass Screening/*methods
Psychiatric Status Rating Scales
100 countdown
Delirium
Delirium superimposed on dementia (DSD)
Inattention
Screening tool
Sixth vital sign

Symptom profile as assessed on delirium rating scale-revised-98 of delirium in respiratory intensive care unit: A study from India. Sharma, A. Malhotra, S. Grover, S. Jindal, S. K. Lung India 2017
Burst-suppression ratio underestimates absolute duration of electroencephalogram suppression compared with visual analysis of intraoperative electroencephalogram. Muhlhofer, W. G. Zak, R. Kamal, T. Rizvi, B. Sands, L. P. Yuan, M. Zhang, X. Leung, J. M. Br J Anaesth 2017
Post-anaesthesia care unit delirium: incidence, risk factors and associated adverse outcomes. Hernandez, B. A. Lindroth, H. Rowley, P. Boncyk, C. Raz, A. Gaskell, A. Garcia, P. S. Sleigh, J. Sanders, R. D. Br J Anaesth 2017
Validation of the 4AT questionnaire in the emergency department Gagné, A. Voyer, P. Boucher, V. Pelletier, M. Gouin, E. Berthelot, S. Daoust, R. Laguë, A. Bédard, C. Émond, M. Canadian Journal of Emergency Medicine 2017

aged
cognitive defect
diagnostic test accuracy study
emergency ward
exposure
female
hospitalization
human
instrument validation
major clinical study
male
questionnaire
screening
sensitivity and specificity
telephone interview
validation process

Incidence, prognostic factors and impact of postoperative delirium after major vascular surgery: A meta-analysis and systematic review. Aitken, S. J. Blyth, F. M. Naganathan, V. Vasc Med 2017

aging
delirium
epidemiology
postoperative complications
prognosis
risk factors
vascular surgical procedures

Altered cortical brain activity in end stage liver disease assessed by multi-channel near-infrared spectroscopy: Associations with delirium. Yoshimura, A. Goodson, C. Johns, J. T. Towe, M. M. Irvine, E. S. Rendradjaja, N. A. Max, L. K. LaFlam, A. Ledford, E. C. Probert, J. Tieges, Z. Edwin, D. H. MacLullich, A. M. J. Hogue, C. W. Lindquist, M. A. Gurakar, A. Neufeld, K. J. Kamiya, A. Sci Rep 2017
Comprehensive geriatric care reduces acute perioperative delirium in elderly patients with hip fractures: A meta-analysis. Wang, Y. Tang, J. Zhou, F. Yang, L. Wu, J. Medicine 2017

Aged
Delirium/*prevention & control
Geriatrics
Hip Fractures/*therapy
Humans
Orthopedic Procedures
Randomized Controlled Trials as Topic

Effect of nocturnal sound reduction on the incidence of delirium in intensive care unit patients: An interrupted time series analysis. van de Pol, I. van Iterson, M. Maaskant, J. Intensive Crit Care Nurs 2017

Aged
Chi-Square Distribution
Critical Illness/psychology
Delirium/*physiopathology/prevention & control
Female
Humans
*Incidence
Intensive Care Units/organization & administration/standards/statistics &
numerical data
Interrupted Time Series Analysis
Male
Middle Aged
Netherlands
Noise/*adverse effects
Sleep
Delirium
Intensive care unit
Noise
Sound

Poorer outcomes and greater healthcare costs for hospitalised older people with dementia and delirium: a retrospective cohort study. Tropea J, LoGiudice D, Liew D, Gorelik A, Brand C International journal of geriatric psychiatry 2017

dementia
delirium
hospital readmissions
health care costs
length of stay
in‐hospital complications
cognitive impairment
hospitalisation
2017
Health Care Utilization
Hospital Admission
Hospitalization
Hospitalized Patients

Attitudes, knowledge and practices concerning delirium: a survey among intensive care unit professionals. Trogrlić, Zoran Ista, Erwin Ponssen, Huibert H. Schoonderbeek, Jeannette F. Schreiner, Frodo Verbrugge, Serge J. Dijkstra, Annemieke Bakker, Jan Jagt, Mathieu Nursing in Critical Care 2017

Attitude of Health Personnel
Guideline Adherence — Netherlands
Delirium — Therapy
Intensive Care Units
Human
Male
Female
Critically Ill Patients
Netherlands
Surveys
Descriptive Statistics
Young Adult
Adult
Middle Age
Analysis of Variance
P-Value
Chi Square Test
Kruskal-Wallis Test
Logistic Regression
Odds Ratio
Data Analysis Software
Funding Source

Can we predict a delirium after cardiac surgery? A validation study of a delirium risk checklist. Ten Broeke, M. Koster, S. Konings, T. Hensens, A. G. van der Palen, J. Eur J Cardiovasc Nurs 2017

Delirium
adult
cardiac
postoperative care

Suvorexant is associated with a low incidence of delirium in critically ill patients: a retrospective cohort study. Masuyama, T. Sanui, M. Yoshida, N. Iizuka, Y. Ogi, K. Yagihashi, S. Nagatomo, K. Sasabuchi, Y. Lefor, A. K. Psychogeriatrics 2018

critically ill
delirium
orexin antagonist
sleep deprivation
suvorexant

Do Risk Prediction Models for Postoperative Delirium Consider Patients' Preoperative Medication Use? Kassie, G. M. Nguyen, T. A. Kalisch Ellett, L. M. Pratt, N. L. Roughead, E. E. Drugs Aging 2018
Predictors and Outcomes of Cardiac Surgery-Associated Delirium. A Single Centre Retrospective Cohort Study. Jones, D. Matalanis, G. Martensson, J. Robbins, R. Shaw, M. Seevanayagam, S. Cowie, D. Bellomo, R. Heart Lung Circ 2018

Cardiac surgery
Confusion
Delirium
Reintubation
Tracheostomy

Delirium in older hospitalized patients-signs and actions: a retrospective patient record review. Johansson, Y. A. Bergh, I. Ericsson, I. Sarenmalm, E. K. BMC Geriatr 2018

*Action by healthcare professionals
*Neurocognitive disorders
*Older hospitalized patients
*Patient participation
*Patient safety
*Person-centered care
*Qualitative content analysis
*Signs of delirium

Delirium-A Framework to Improve Acute Care for Older Persons. Inouye, S. K. J Am Geriatr Soc 2018

Acute care for elders
Confusion Assessment Method
Delirium
Hospital Elder Life Program

The minimal clinically important difference of the Richmond Agitation-Sedation Scale in patients with cancer with agitated delirium. Hui, D. Hess, K. Dibaj, S. S. Arthur, J. Dev, R. Dalal, S. Reddy, S. Bruera, E. Cancer 2018

delirium
minimal clinically important difference
neoplasms
palliative care
patient outcome assessment
randomized controlled trial

The use of cerebral imaging for investigating delirium aetiology. Hijazi, Z. Lange, P. Watson, R. Maier, A. B. Eur J Intern Med 2018

Delirium
Diagnostic imaging
Diffusion magnetic resonance imaging
Magnetic resonance imaging
Neuroimaging
Tomography, X-ray computed

Medication Profiles of Patients with Cognitive Impairment and High Anticholinergic Burden. Green, A. R. Reifler, L. M. Boyd, C. M. Weffald, L. A. Bayliss, E. A. Drugs Aging 2018
Delirium Assessment Tools for Use in Critically Ill Adults: A Psychometric Analysis and Systematic Review. Gelinas, C. Berube, M. Chevrier, A. Pun, B. T. Ely, E. W. Skrobik, Y. Barr, J. Crit Care Nurse 2018
Postoperative Delirium in Glioblastoma Patients: Risk Factors and Prognostic Implications. Flanigan, P. M. Jahangiri, A. Weinstein, D. Dayani, F. Chandra, A. Kanungo, I. Choi, S. Sankaran, S. Molinaro, A. M. McDermott, M. W. Berger, M. S. Aghi, M. K. Neurosurgery 2018
The delirium and population health informatics cohort study protocol: ascertaining the determinants and outcomes from delirium in a whole population. Davis, D. Richardson, S. Hornby, J. Bowden, H. Hoffmann, K. Weston-Clarke, M. Green, F. Chaturvedi, N. Hughes, A. Kuh, D. Sampson, E. Mizoguchi, R. Cheah, K. L. Romain, M. Sinha, A. Jenkin, R. Brayne, C. MacLullich, A. BMC Geriatr 2018

*Delirium
*Dementia
*Epidemiology

Cerebral oximetry during preoperative resuscitation in elderly patients with hip fracture: a prospective observational study. Clemmesen, C. G. Pedersen, L. M. Hougaard, S. Andersson, M. L. Rosenkvist, V. Nielsen, H. B. Palm, H. Foss, N. B. J Clin Monit Comput 2018

Delirium
Haemodynamic
Hip fractures
Spectroscopy near-infrared

Clinical characteristics associated with the onset of delirium among long-term nursing home residents. Cheung, E. N. M. Benjamin, S. Heckman, G. Ho, J. M. Lee, L. Sinha, S. K. Costa, A. P. BMC Geriatr 2018

*Delirium
*Nursing homes
*Pain

Evaluation of a multicomponent pathway to address inpatient delirium on a neurosciences ward. Brown, E. G. Josephson, S. A. Anderson, N. Reid, M. Lee, M. Douglas, V. C. BMC Health Serv Res 2018

*Cognitive aging
*Delirium
*Outcome research
*Patient safety

Subsyndromal delirium in the intensive care setting: Phenomenological characteristics and discrimination of subsyndromal delirium versus no and full-syndromal delirium. Boettger S, Nuñez DG, Meyer R, Richter A, Schubert M, Jenewein J Palliative & supportive care 2017

Diagnostic and Statistical Manual of Mental Disorders
1998 (drs-r-98)
4th ed.
Delirium
Delirium Rating Scale-Revised
Full-syndromal
Intensive care unit (ICU)
Phenomenology
Subsyndromal
Text Revision (DSM-IV-TR)

Incidence, risk factors, and clinical implications of post-operative delirium in lung transplant recipients. Anderson, B. J. Chesley, C. F. Theodore, M. Christie, C. Tino, R. Wysoczanski, A. Ramphal, K. Oyster, M. Kalman, L. Porteous, M. K. Bermudez, C. A. Cantu, E. Kolson, D. L. Christie, J. D. Diamond, J. M. J Heart Lung Transplant 2018

acidic protein
benzodiazepines
delirium
glial fibrillary
lung transplantation
neuron-specific enolase
postoperative complications
primary graft dysfunction

Delirium and correlates of delirium among newly admitted elderly patients: A crosssectional study in a Saudi general hospital. Alamri, S. H. Ashanqity, O. A. Alshomrani, A. B. Elmasri, A. H. Saeed, M. B. Yahya, S. A. Almasoud, A. I. Adam, Y. Alamoudi, H. M. Mukhtar, A. M. Annals of Saudi Medicine 2018

urinary catheter
alanine aminotransferase
aspartate aminotransferase
calcium
creatinine
electrolyte
glucose
hemoglobin
adult
age
aged
alanine aminotransferase blood level
alcohol withdrawal syndrome
article
aspartate aminotransferase blood level
calcium blood level
cerebrovascular accident
cognition
cognitive defect
comorbidity
Confusion Assessment Method
correlation analysis
correlational study
creatinine blood level
cross-sectional study
delirium
female
general hospital
glucose blood level
heart disease
heart failure
hemoglobin blood level
hospital admission
human
hypoglycemia
infection
invasive procedure
kidney failure
leukocyte
leukocytosis
liver failure
major clinical study
male
malnutrition
medical record
mental disease assessment
neurologic disease
physician
prevalence
priority journal
risk factor
Saudi Arabia
tertiary care center
unemployment
urea nitrogen blood level

Preoperative Cognitive Impairment As a Predictor of Postoperative Outcomes in a Collaborative Care Model. Zietlow, K. McDonald, S. R. Sloane, R. Browndyke, J. Lagoo-Deenadayalan, S. Heflin, M. T. J Am Geriatr Soc 2018

co-management
cognitive impairment
older adults
postoperative outcomes

Identifying Older Adults at Risk of Delirium Following Elective Surgery: A Systematic Review and Meta-Analysis. Watt, J. Tricco, A. C. Talbot-Hamon, C. Pham, B. Rios, P. Grudniewicz, A. Wong, C. Sinclair, D. Straus, S. E. J Gen Intern Med 2018

delirium
elective surgery
older adults
perioperative medicine
prognostic factors

Sedative Plasma Concentrations and Delirium Risk in Critical Illness. Stollings, J. L. Thompson, J. L. Ferrell, B. A. Scheinin, M. Wilkinson, G. R. Hughes, C. G. Shintani, A. K. Ely, E. W. Girard, T. D. Pandharipande, P. P. Patel, M. B. Ann Pharmacother 2018

analgesics
assays
critical care
drug safety
drug trials
pharmacodynamics
sedatives
toxicity