What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Neuropsychiatric adverse events of chloroquine: a real-world pharmacovigilance study using the FDA Adverse Event Reporting System (FAERS) database
- Authors
- Sato, K. Mano, T. Iwata, A. Toda, T.
- Year
- 2020
- Journal
- Biosci Trends
- Abstract
In late March and early April 2020, the antimalarial drug, chloroquine, has been approved as an emergency treatment for the coronavirus disease 2019 (COVID-19) in the United States and in Europe. Although infrequent, neuropsychiatric symptoms have been reported in patients who received chloroquine for the treatment of malaria or autoimmune diseases. In this study, aiming to investigate these adverse events (AEs) using a large self-reporting database, we conducted a disproportionality analysis for the detection of neuropsychiatric AE signals associated with the use of chloroquine (or hydroxychloroquine), reported to FDA Adverse Event Reporting System (FAERS) database between the fourth quarter of 2012 and the fourth quarter of 2019. We included 2,389,474 AE cases, among which 520 cases developed neuropsychiatric AE following the use of chloroquine. Adjusted reporting odds ratio (ROR) for the development of each of the neuropsychiatric AEs following the use of chloroquine was calculated using a multilevel model: exposure to chloroquine was associated with a statistically significant high reporting of amnesia, delirium, hallucinations, depression, and loss of consciousness, (lower 95% confidence interval of the adjusted ROR > 1), although the degree of increase in their ROR was limited. There was no statistically significant high reporting of any other neuropsychiatric AE, including suicide, psychosis, confusion, and agitation. Current pharmacovigilance study results did not suggest any potential link between the use of chloroquine and an increased risk of suicide, psychosis, confusion, and agitation, which would be informative during the emergency use of chloroquine for the treatment of COVID-19.
- PMID
- Keywords
Adverse Drug Reaction Reporting Systems
Aged
Betacoronavirus/isolation & purification
Chloroquine/administration & dosage/ adverse effects
Databases, Factual
Female
Humans
Male
Mental Disorders/ chemically induced
Middle Aged
Neurotoxicity Syndromes/ etiology
Pharmacovigilance
Retrospective Studies
United States
United States Food and Drug Administration
Covid-19
Faers
adverse events
chloroquine
real-world data
- Page(s)
- 139-143
- Volume
- 14
- Issue
- 2
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Development and validation of an automated delirium risk assessment system (Auto-DelRAS) implemented in the electronic health record system. | Moon, K. J. Jin, Y. Jin, T. Lee, S. M. | Int J Nurs Stud | 2017 |
Auto-DelRAS |
| Efficacy of Ramelteon for delirium after lung cancer surgery. | Miyata R, Omasa M, Fujimoto R, Ishikawa H, Aoki M | Interactive cardiovascular and thoracic surgery | 2016 |
indene derivative |
| Risk Factors for Postoperative Delirium in Abdominal Surgery: A Proposal of a Postoperative Delirium Risk Score in Abdominal Surgery. | Miyagawa, Y. Yokoyama, Y. Fukuzawa, S. Fukata, S. Ando, M. Kawamura, T. Yamada, K. Nagino, M. | Digestive Surgery | 2017 |
serum albumin |
| Long-term cognitive impairment and delirium in intensive care: A prospective cohort study. | Mitchell, M. L. Shum, D. H. K. Mihala, G. Murfield, J. E. Aitken, L. M. | Aust Crit Care | 2017 |
Cognition |
| Prevalence of delirium in advanced cancer patients in home care and hospice and outcomes after 1 week of palliative care. | Mercadante, S. Masedu, F. Balzani, I. De Giovanni, D. Montanari, L. Pittureri, C. Berte, R. Russo, D. Ursini, L. Marinangeli, F. Aielli, F. | Support Care Cancer | 2017 |
Advanced cancer |
| Characterizing and predicting rates of delirium across general hospital settings. | McCoy, Thomas H. Hart, Kamber L. Perlis, Roy H. | General Hospital Psychiatry | 2017 |
Delirium |
| Environmental and Clinical Risk Factors for Delirium in a Neurosurgical Center: A Prospective Study. | Matano, F. Mizunari, T. Yamada, K. Kobayashi, S. Murai, Y. Morita, A. | World Neurosurg | 2017 |
Delirium |
| Genetic and environmental factors associated with delirium severity in older adults with dementia | Massimo, Lauren Munoz, Elizabeth Hill, Nikki Mogle, Jacqueline Mulhall, Paula McMillan, Corey T. Clare, Linda Vandenbergh, David Fick, Donna Kolanowski, Ann | International Journal of Geriatric Psychiatry | 2017 |
delirium |
| Delirium in Hospitalized Older Adults. | Marcantonio, E. R. | N Engl J Med | 2017 |
Aged |
| A post cardiac surgery intervention to manage delirium involving families: a randomized pilot study. | Mailhot, T. Cossette, S. Cote, J. Bourbonnais, A. Cote, M. C. Lamarche, Y. Denault, A. | Nurs Crit Care | 2017 |
Cardiac surgery |
| The influence of analgesic-based sedation protocols on delirium and outcomes in critically ill patients: A randomized controlled trial. | Liu, D. Lyu, J. Zhao, H. An, Y. | PloS One | 2017 |
Adolescent |
| Impact of dexmedetomidine on the incidence of delirium in elderly patients after cardiac surgery: A randomized controlled trial. | Li, X. Yang, J. Nie, X. L. Zhang, Y. Li, X. Y. Li, L. H. Wang, D. X. Ma, D. | PloS One | 2017 |
NCT02267538 |
| Perioperative Gabapentin Does Not Reduce Postoperative Delirium in Older Surgical Patients: A Randomized Clinical Trial. | Leung, J. M. Sands, L. P. Chen, N. Ames, C. Berven, S. Bozic, K. Burch, S. Chou, D. Covinsky, K. Deviren, V. Kinjo, S. Kramer, J. H. Ries, M. Tay, B. Vail, T. Weinstein, P. Chang, S. Meckler, G. Newman, S. Tsai, T. Voss, V. Youngblom, E. | Anesthesiology | 2017 | |
| Cerebral oximetry and postoperative delirium after cardiac surgery: a randomised, controlled trial. | Lei, L. Katznelson, R. Fedorko, L. Carroll, J. Poonawala, H. Machina, M. Styra, R. Rao, V. Djaiani, G. | Anaesthesia | 2017 |
cardiac surgery |
| Psychiatric symptomatology after delirium: a systematic review. | Langan, C. Sarode, D. P. Russ, T. C. Shenkin, S. D. Carson, A. Maclullich, A. M. J. | Psychogeriatrics | 2017 |
anxiety |
| Multicenter assessment of sedation and delirium practices in the intensive care units in Poland - is this common practice in Eastern Europe? | Kotfis, K. Zegan-Barańska, M. Zukowski, M. Kusza, K. Kaczmarczyk, M. Ely, E. W. | BMC Anesthesiology | 2017 |
benzodiazepine derivative |
| Complications Associated With Spine Surgery in Patients Aged 80 Years or Older: Japan Association of Spine Surgeons with Ambition (JASA) Multicenter Study | Kobayashi, K. Imagama, S. Ando, K. Ishiguro, N. Yamashita, M. Eguchi, Y. Matsumoto, M. Ishii, K. Hikata, T. Seki, S. Terai, H. Suzuki, A. Tamai, K. Aramomi, M. Ishikawa, T. Kimura, A. Inoue, H. Inoue, G. Miyagi, M. Saito, W. Yamada, K. Hongo, M. Nishimura | Global Spine J | 2017 |
anticoagulant agent |
| Risk Factors for Delirium After Spine Surgery in Extremely Elderly Patients Aged 80 Years or Older and Review of the Literature: Japan Association of Spine Surgeons with Ambition Multicenter Study. | Kobayashi, K. Imagama, S. Ando, K. Ishiguro, N. Yamashita, M. Eguchi, Y. Matsumoto, M. Ishii, K. Hikata, T. Seki, S. Terai, H. Suzuki, A. Tamai, K. Aramomi, M. Ishikawa, T. Kimura, A. Inoue, H. Inoue, G. Miyagi, M. Saito, W. Yamada, K. Hongo, M. Matsuoka, | Global Spine J | 2017 |
complication |
| Delirium characteristics and outcomes in medical and surgical lnpatients: A subgroup analysis. | Kim, S. Kim, J. J. Oh, J. Park, J. Park, J. Y. | J Crit Care | 2017 |
Delirium duration |
| Persistence of Delirium after Cessation of Sedatives and Analgesics and Impact on Clinical Outcomes in Critically Ill Patients. | Kenes, M. T. Stollings, J. L. Wang, L. Girard, T. D. Ely, E. W. Pandharipande, P. P. | Pharmacotherapy | 2017 |
critical care |
| South Korean Family Caregiver Involvement in Delirium Care: A Qualitative Descriptive Study. | Kang, Y. Moyle, W. Cooke, M. O'Dwyer, S. | J Gerontol Nurs | 2017 | |
| Validity of the Delirium Observation Screening Scale in Identifying Delirium in Home Hospice Patients. | Jorgensen SM, Carnahan RM, Weckmann MT | The American journal of hospice & palliative care | 2016 |
delirium screening |
| Discharge Plans for Geriatric Inpatients with Delirium: A Plan to Stop Antipsychotics? | Johnson, K. G. Fashoyin, A. Madden-Fuentes, R. Muzyk, A. J. Gagliardi, J. P. Yanamadala, M. | J Am Geriatr Soc | 2017 |
Aged |
| Trials of statins in delirium-stymied by complex methods? | Skrobik, Y. Devlin, J. | Lancet Respir med | 2017 | |
| An integrative literature review exploring the clinical management of delirium in patients with advanced cancer | Lawley, H. Hewison, A. | J Clin Nurs | 2017 |
advanced cancer |
| Comparison of propofol and dexmedetomidine infused overnight to treat hyperactive and mixed ICU delirium: a protocol for the Basel ProDex clinical trial. | Hollinger, A. Ledergerber, K. von Felten, S. Sutter, R. Ruegg, S. Gantner, L. Zimmermann, S. Blum, A. Steiner, L. A. Marsch, S. Siegemund, M. | BMJ Open | 2017 |
Dexmedetomidine |
| Protocol for an observational study of delirium in the post-anaesthesia care unit (PACU) as a potential predictor of subsequent postoperative delirium. | Cui, V. Tedeschi, C. M. Kronzer, V. L. McKinnon, S. L. Avidan, M. S. | BMJ Open | 2017 |
adult intensive & critical care |
| Debate article: Antipsychotic medications are clinically useful for the treatment of delirium. | Meagher, D. Agar, M. R. Teodorczuk, A. | Int J Geriatr Psychiatry | 2017 |
antipsychotics |
| A Novel Stress-Diathesis Model to Predict Risk of Post-operative Delirium: Implications for Intra-operative Management. | El-Gabalawy, R. Patel, R. Kilborn, K. Blaney, C. Hoban, C. Ryner, L. Funk, D. Legaspi, R. Fisher, J. A. Duffin, J. Mikulis, D. J. Mutch, W. A. C. | Front Aging Neurosci | 2017 |
neuroimaging |
| Treatment of asymptomatic UTI in older delirious medical in-patients: A prospective cohort study. | Dasgupta, M. Brymer, C. Elsayed, S. | Arch Gerontol Geriatr | 2017 |
Aged |
| Early geriatric consultation increases adherence to TQIP Geriatric Trauma Management Guidelines. | Southerland, L. T. Gure, T. R. Ruter, D. I. Li, M. M. Evans, D. C. | J Surg Res | 2017 |
Aged |
| Post-Intensive Care Unit Psychiatric Comorbidity and Quality of Life. | Wang, S. Mosher, C. Perkins, A. J. Gao, S. Lasiter, S. Khan, S. Boustani, M. Khan, B. | Journal of Hospital Medicine | 2017 | |
| Potentially modifiable factors contributing to sepsis-associated encephalopathy. | Sonneville, Romain Montmollin, Etienne Poujade, Julien Garrouste-Orgeas, Maïté Souweine, Bertrand Darmon, Michael Mariotte, Eric Argaud, Laurent Barbier, François Goldgran-Toledano, Dany Marcotte, Guillaume Dumenil, Anne-Sylvie Jamali, Samir Lacave, Gu | Intensive Care Medicine | 2017 | |
| Comprehensive Geriatric Assessment for Prevention of Delirium After Hip Fracture: A Systematic Review of Randomized Controlled Trials. | Shields L, Henderson V, Caslake R | Journal of the American Geriatrics Society | 2017 |
Aged |
| Age- and gender-related peculiarities of patients with delirium in the cardiac intensive care unit. | Serpytis, P. Navickas, P. Navickas, A. Serpytis, R. Navickas, G. Glaveckaite, S. | Kardiol Pol | 2017 |
age |
| Delirium Frequency and Risk Factors Among Patients With Cancer in Palliative Care Unit. | Şenel G, Uysal N, Oguz G, Kaya M, Kadioullari N, Koçak N, Karaca S | The American journal of hospice & palliative care | 2017 |
adult |
| Plasma melatonin levels in hip fracture patients with and without delirium: A confirmation study. | Scholtens, R. M. van Munster, B. C. van Faassen, M. van Kempen, M. F. Kema, I. P. de Rooij, S. E. | Mech Ageing Dev | 2017 |
Aged |
| Association between delirium and cognitive change after cardiac surgery. | Sauer, A. C. Veldhuijzen, D. S. Ottens, T. H. Slooter, A. J. C. Kalkman, C. J. van Dijk, D. | Br J Anaesth | 2017 |
cardiac surgical procedures |
| Effectiveness and Safety of an Extended ICU Visitation Model for Delirium Prevention: A Before and After Study. | Rosa, R. G. Tonietto, T. F. da Silva, D. B. Gutierres, F. A. Ascoli, A. M. Madeira, L. C. Rutzen, W. Falavigna, M. Robinson, C. C. Salluh, J. I. Cavalcanti, A. B. Azevedo, L. C. Cremonese, R. V. Haack, T. R. Eugenio, C. S. Dornelles, A. Bessel, M. Teles, | Crit Care Med | 2017 |
Aged |
| Association of postoperative delirium with markers of neurodegeneration and brain amyloidosis: a pilot study. | Rolandi, E. Cavedo, E. Pievani, M. Galluzzi, S. Ribaldi, F. Buckley, C. Cunningham, C. Guerra, U. P. Musarra, M. Morzenti, S. Magnaldi, S. Patassini, M. Terragnoli, F. Matascioli, L. Franzoni, S. Annoni, G. Carnevali, L. Bellelli, G. Frisoni, G. B. | Neurobiol Aging | 2017 |
Alzheimer’s disease |
| Misidentification of mental health symptoms in presence of organic diseases and delirium during psychiatric liaison consulting. | Otani, V. H. O. Otani, Tzds Freirias, A. Calfat, E. L. B. Aoki, P. S. Cordeiro, Q. Junior Kanaan, R. A. A. Cross, S. Liersch-Sumskis, S. Uchida, R. R. | Int J Psychiatry Clin Pract | 2017 |
Diagnostic errors |
| A randomised trial of peri-operative positive airway pressure for postoperative delirium in patients at risk for obstructive sleep apnoea after regional anaesthesia with sedation or general anaesthesia for joint arthroplasty. | Nadler, J. W. Evans, J. L. Fang, E. Preud'Homme, X. A. Daughtry, R. L. Chapman, J. B. Bolognesi, M. P. Attarian, D. E. Wellman, S. S. Krystal, A. D. | Anaesthesia | 2017 |
clinical trial |
| Using anchors from free text in electronic health records to diagnose postoperative delirium. | Mikalsen, K. Ø Soguero-Ruiz, C. Jensen, K. Hindberg, K. Gran, M. Revhaug, A. Lindsetmo, R. O. Skrøvseth, S. O. Godtliebsen, F. Jenssen, R. | Computer Methods and Programs in Biomedicine | 2017 |
haloperidol |
| Postinjection delirium/sedation syndrome in patients with schizophrenia receiving olanzapine long-acting injection: results from a large observational study. | Meyers, K. J. Upadhyaya, H. P. Landry, J. L. Chhabra-Khanna, R. Falk, D. M. Seetharama Rao, B. Jones, M. E. | BJ Psych Open | 2017 | |
| Risk Factors for Delirium in Older Medical Inpatients in Tanzania. | Lewis, E. G. Banks, J. Paddick, S. M. Duinmaijer, A. Tucker, L. Kisoli, A. Cletus, J. Lissu, C. Kilonzo, K. Cosker, G. Mukaetova-Ladinska, E. B. Dotchin, C. Gray, W. Walker, R. Urasa, S. | Dement Geriatr Cogn Disord | 2017 |
Delirium |
| The experience of intensive care nurses caring for patients with delirium: A phenomenological study. | LeBlanc, A. Bourbonnais, F. F. Harrison, D. Tousignant, K. | Intensive Crit Care Nurs | 2017 |
Critical care |
| Pre-stroke apathy symptoms are associated with an increased risk of delirium in stroke patients | Klimiec, E. Kowalska, K. Pasinska, P. Klimkowicz-Mrowiec, A. Szyper, A. Pera, J. Slowik, A. Dziedzic, T. | Sci Rep | 2017 | |
| Current practice and opinions of hospital pharmacists regarding their role in the screening, prevention and treatment of delirium. | Kassie, G. M. Kalisch Ellett, L. M. Nguyen, T. A. Roughead, E. E. | Int J Clin Pharm | 2017 |
Australia |
| An educational programme to improve acute care nurses' knowledge, attitudes and family caregiver involvement in care of people with cognitive impairment. | Kang, Y. Moyle, W. Cooke, M. O'Dwyer, S. T. | Scand J Caring Sci | 2017 |
carers |
| Prognostic value of acute delirium recovery in older adults. | Jorge-Ripper C, Alemán MR, Ros R, Aguilera S, González-Reimers E, Espelosín E, Santolaria F | Geriatrics & gerontology international | 2016 |
Sepsis — Prognosis |
| Perceptions, attitudes, and current practices regards delirium in China: A survey of 917 critical care nurses and physicians in China. | Xing, J. Sun, Y. Jie, Y. Yuan, Z. Liu, W. | Medicine | 2017 | |
| Postoperative Delirium in Patients after Pancreaticoduodenectomy. | Ito Y, Abe Y, Handa K, Shibutani S, Egawa T, Nagashima A, Kitago M, Itano O, Kitagawa Y | Digestive surgery | 2017 |
Age Factors, Aged, Aged, 80 and over, Area Under Curve, Biliary Tract Neoplasms, surgery, Comorbidity, Delirium, etiology, Female, Humans, Male, Middle Aged, Pancreatic Neoplasms, surgery, Pancreaticoduodenectomy, adverse effects, Postoperative Complications, etiology, ROC Curve, Retrospective Studies, Risk Factors |
| Effect of lorazepam with haloperidol vs haloperidol alone on agitated delirium in patients with advanced cancer receiving palliative care: A randomized clinical trial | Hui, D. Frisbee-Hume, S. Wilson, A. Dibaj, S. S. Nguyen, T. De La Cruz, M. Walker, P. Zhukovsky, D. S. Delgado-Guay, M. Vidal, M. Epner, D. Reddy, A. Tanco, K. Williams, J. Hall, S. Liu, D. Hess, K. Amin, S. Breitbart, W. Bruera, E. | JAMA | 2017 |
NCT01949662 |
| Surgery and Anesthesia Exposure Is Not a Risk Factor for Cognitive Impairment After Major Noncardiac Surgery and Critical Illness. | Hughes CG, Patel MB, Jackson JC, Girard TD, Geevarghese SK, Norman BC, Thompson JL, Chandrasekhar R, Brummel NE, May AK, Elstad MR, Wasserstein ML, Goodman RB, Moons KG, Dittus RS, Ely EW, Pandharipande PP, | Annals of surgery | 2016 |
Aged |
| Incidence of postoperative delirium in patients undergoing total knee arthroplasty-an Asian perspective. | Huang, J. Bin Abd Razak, H. R. Yeo, S. J. | Ann Transl Med | 2017 |
Asian |
| Reevaluation of a clinical resource for assessment of delirium, dementia, and depression. | Horvath, K. J. Burns, T. Fernandez, C. Huh, J. W. T. Moorer, J. Thielke, S. Trittschuh, E. Cooley, S. | Gerontol Geriatr Educ | 2017 |
Delirium |
| New institutionalisation following acute hospital admission: A retrospective cohort study | Harrison, J. K. Garrido, A. G. Rhynas, S. J. Logan, G. Maclullich, A. M. J. Macarthur, J. Shenkin, S. | Age & Ageing | 2017 |
neuroleptic agent |
| Excited Delirium: A Systematic Review. | Gonin, P. Beysard, N. Yersin, B. Carron, P. N. | Acad Emerg Med | 2017 |
Agitation |
| Effectiveness of a Multifaceted Delirium Screening, Prevention, and Treatment Initiative on the Rate of Delirium Falls in the Acute Care Setting. | Ferguson, A. Uldall, K. Dunn, J. Blackmore, C. C. Williams, B. | J Nurs Care Qual | 2017 | |
| Depression as an independent predictor of postoperative delirium in spine deformity patients undergoing elective spine surgery. | Elsamadicy, A. A. Adogwa, O. Lydon, E. Sergesketter, A. Kaakati, R. Mehta, A. I. Vasquez, R. A. Cheng, J. Bagley, C. A. Karikari, I. O. | J Neurosurg Spine | 2017 |
Academic Medical Centers |
| Functional trajectories of older patients admitted to an Acute Care Unit for Elders. | D'Onofrio, A. Bula, C. Rubli, E. Butrogno, F. Morin, D. | Int J Older People Nurs | 2017 |
delirium |
| Managing delirium behaviors with one-to-one sitters. | Colella, J. Aroh, D. Douglas, C. VanBuitenen, N. Galesi, J. Castro, A. Tank, L. Parulekar, M. Menacker, M. | Nurs Manage | 2017 | |
| Clinical Assessment and Management of Delirium in the Palliative Care Setting | Bush, Shirley Lawlor, Peter Tierney, Sallyanne | Drugs | 2017 |
Delirium — Therapy |
| Perceptions of workload burden and adherence to ABCDE bundle among intensive care providers. | Boehm, Leanne M. | American Journal of Critical Care | 2017 |
Critical Care Nursing |
| Optimizing Surgical Quality Datasets to Care for Older Adults: Lessons from the American College of Surgeons NSQIP Geriatric Surgery Pilot. | Berian, J. R. Zhou, L. Hornor, M. A. Russell, M. M. Cohen, M. E. Finlayson, E. Ko, C. Y. Robinson, T. N. Rosenthal, R. A. | J Am Coll Surg | 2017 | |
| Post-ICU psychological morbidity in very long ICU stay patients with ARDS and delirium. | Bashar, F. R. Vahedian-Azimi, A. Hajiesmaeili, M. Salesi, M. Farzanegan, B. Shojaei, S. Goharani, R. Madani, S. J. Moghaddam, K. G. Hatamian, S. Moghaddam, H. J. Mosavinasab, S. M. M. Elamin, E. M. Miller, A. C. | J Crit Care | 2017 |
Acute respiratory distress syndrome |
| The prevalence of undiagnosed pre-surgical cognitive impairment and its post-surgical clinical impact in elderly patients undergoing surgery for adult spinal deformity. | Adogwa, O. Elsamadicy, A. A. Lydon, E. Vuong, V. D. Cheng, J. Karikari, I. O. Bagley, C. A. | J Spine Surg | 2017 |
Surgery |
| A comparison of outcomes according to different diagnostic systems for delirium (DSM-5, DSM-IV, CAM, and DRS-R98). | Adamis, D. Meagher, D. Rooney, S. Mulligan, O. McCarthy, G. | Int Psychogeriatr | 2017 |
Dsm |
| Antipsychotic prescription to identify delirium: results from two cohorts. | Zimmerman, K. M. Paquin, A. M. Rudolph, J. L. | Clin Pharmacol | 2017 |
delirium antipsychotic aged |
| Preoperative severe hypoalbuminemia is associated with an increased risk of postoperative delirium in elderly patients: Results of a secondary analysis. | Zhang, D. F. Su, X. Meng, Z. T. Cui, F. Li, H. L. Wang, D. X. Li, X. Y. | J Crit Care | 2017 |
Delirium |
| Rivastigmine patch reduces the incidence of postoperative delirium in older patients with cognitive impairment | Young, Y. C. Shin, H. W. Choi, B. S. Kim, S. Lee, J. Y. Ha, Y. C. | Int J Geriatr Psychiatry | 2017 |
acetylcholinesterase inhibitors |
| Effects of nimodipine on postoperative delirium in elderly under general anesthesia: A prospective, randomized, controlled clinical trial | Ya-Nan, Li Qi, Zhang Chun-Ping, Yin Yang-Yang, Guo Shu-Ping, Huo Liang, Wang Qiu-Jun, Wang Li, Ya-Nan Zhang, Qi Yin, Chun-Ping Guo, Yang-Yang Huo, Shu-Ping Wang, Liang Wang, Qiu-Jun | Medicine | 2017 | |
| Association of intraoperative changes in brain-derived neurotrophic factor and postoperative delirium in older adults. | Wyrobek, J. LaFlam, A. Max, L. Tian, J. Neufeld, K. J. Kebaish, K. M. Walston, J. D. Hogue, C. W. Riley, L. H. Everett, A. D. Brown, C. H. th | Br J Anaesth | 2017 |
Bdnf |
| Preoperative geriatric assessment reduced hospital stay and complications in patients ≥65 y having vascular surgery. | Weed, H. G. | Annals of Internal Medicine | 2017 |
ISRCTN23142588 |
| The Risk Factors of Postoperative Delirium after Total Knee Arthroplasty. | Wang, L. Seok, S. Kim, S. Kim, K. Lee, S. Lee, K. | J Knee Surg | 2017 | |
| Risk factors for the incidence of delirium in cerebrovascular patients in a Neurosurgery Intensive Care Unit: A prospective study. | Wang, J. Ji, Y. Wang, N. Chen, W. Bao, Y. Qin, Q. Xiao, Q. Li, S. | J Clin Nurs | 2017 |
delirium (mental health nursing) |
| Clock-Drawing Test as a Bedside Assessment of Post-operative Delirium Risk in Elderly Patients with Accidental Hip Fracture. | Vasilian, C. C. Tamasan, S. C. Lungeanu, D. Poenaru, D. V. | World J Surg | 2017 | |
| A prospective observational study to investigate utility of the Delirium Observational Screening Scale (DOSS) to detect delirium in care home residents. | Teale, E. A. Munyombwe, T. Schuurmans, M. Siddiqi, N. Young, J. | Age & Ageing | 2017 |
Delirium Observation Screening Scale |
| Randomized phase II study of TJ-54 (Yokukansan) for postoperative delirium in gastrointestinal and lung malignancy patients. | Sugano, N. Aoyama, T. Sato, T. Kamiya, M. Amano, S. Yamamoto, N. Nagashima, T. Ishikawa, Y. Masudo, K. Taguri, M. Yamanaka, T. Yamamoto, Y. Matsukawa, H. Shiraisi, R. Oshima, T. Yukawa, N. Rino, Y. Masuda, M. | Mol Clin Oncol | 2017 |
Yokukansan |
| Postoperative delirium in elderly patients is associated with subsequent cognitive impairment. | Sprung, J. Roberts, R. O. Weingarten, T. N. Nunes Cavalcante, A. Knopman, D. S. Petersen, R. C. Hanson, A. C. Schroeder, D. R. Warner, D. O. | Br J Anaesth | 2017 |
aged, humans |
| Delirium Following Transcatheter Aortic Valve Replacement: National Inpatient Sample Analysis. | Soundhar, A. Udesh, R. Mehta, A. Schindler, J. Jeevanantham, V. Gleason, T. Thirumala, P. D. | Journal of Cardiothoracic and Vascular Anesthesia | 2017 |
carotid artery obstruction |
| The Effects of Delirium Prevention Guidelines on Elderly Stroke Patients | Song, J. Lee, M. Jung, D. | Clin Nurs Res | 2017 |
delirium |
| Postoperative Delirium in Elderly Patients Undergoing Major Spinal Surgery: Role of Cerebral Oximetry. | Soh S, Shim JK, Song JW, Kim KN, Noh HY, Kwak YL | Journal of neurosurgical anesthesiology | 2016 | |
| Age and gender-related peculiarities of patients with delirium in the cardiac intensive care unit. | Serpytis, P. Navickas, P. Navickas, A. Serpytis, R. Navickas, G. Glaveckaite, S. | Kardiol Pol | 2017 |
Iccu |
| Outcomes of subsyndromal delirium in ICU: a systematic review and meta-analysis. | Serafim, R. B. Soares, M. Bozza, F. A. Lapa, E. Silva J. R. Dal-Pizzol, F. Paulino, M. C. Povoa, P. Salluh, J. I. F. | Crit Care | 2017 |
Critically ill |
| Haloperidol versus placebo for delirium prevention in acutely hospitalised older at risk patients: a multi-centre double-blind randomised controlled clinical trial. | Schrijver, E. J. M. de Vries, O. J. van de Ven, P. M. Bet, P. M. Kamper, A. M. Diepeveen, S. H. A. van Marum, R. J. van Strien, A. M. Anten, S. Lagaay, A. M. Boelaarts, L. Bloemers, F. W. Kramer, M. H. H. Nanayakkara, P. W. B. | Age & Ageing | 2017 |
aged 80 and over |
| The impact of delirium on outcomes in acute, non-intubated cardiac patients. | Sato K, Kubota K, Oda H, Taniguchi T | European heart journal. Acute cardiovascular care | 2015 |
Aging |
| Epidemiology and outcomes of people with dementia, delirium, and unspecified cognitive impairment in the general hospital: prospective cohort study of 10,014 admissions. | Reynish, Emma L. Hapca, Simona M. De Souza, Nicosha Cvoro, Vera Donnan, Peter T. Guthrie, Bruce | BMC Medicine | 2017 | |
| Alzheimer's-related cortical atrophy is associated with postoperative delirium severity in persons without dementia. | Racine, A. M. Fong, T. G. Travison, T. G. Jones, R. N. Gou, Y. Vasunilashorn, S. M. Marcantonio, E. R. Alsop, D. C. Inouye, S. K. Dickerson, B. C. | Neurobiol Aging | 2017 |
Alzheimer’s disease |
| Delayed Recall and Working Memory MMSE Domains Predict Delirium following Cardiac Surgery. | Price, C. C. Garvan, C. Hizel, L. Lopez, M. G. Billings, F. T. | J Alzheimers Dis | 2017 |
Alzheimer’s disease |
| The detection, diagnosis, and impact of cognitive impairment among inpatients aged 65 years and over in an Irish general hospital - a prospective observational study. | Power, C. Duffy, R. Bates, H. Healy, M. Gleeson, P. Lawlor, B. A. Greene, E. | Int Psychogeriatr | 2017 |
cognitive impairment |
| Incidence and predictors of postoperative delirium after cytoreduction surgery-hyperthermic intraperitoneal chemotherapy. | Plas, M. Hemmer, P. H. J. Been, L. B. van Ginkel, R. J. de Bock, G. H. van Leeuwen, B. L. | J Surg Oncol | 2017 |
C-reactive protein |
| Role of Ramelteon in Reduction of As-Needed Antipsychotics in Elderly Patients with Delirium in a General Hospital Setting. | Pinkhasov, A. James, S. A. Fazzari, M. Singh, D. Lam, S. | Clin Drug Investig | 2017 | |
| Delirium after fast-track hip and knee arthroplasty - a cohort study of 6331 elderly patients. | Petersen, P. B. Jorgensen, C. C. Kehlet, H. | Acta Anaesthesiol Scand | 2017 | |
| Delirium Risk of Dexmedetomidine and Midazolam in Patients Treated with Postoperative Mechanical Ventilation: a Meta-analysis. | Peng, W. Shimin, S. Hongli, W. Yanli, Z. Ying, Z. | Open Med | 2017 |
Delirium |
| Humanizing the treatment of hyperactive delirium in the last days of life. | Pandharipande, P. P. Ely, E. W. | JAMA | 2017 |
haloperidol |
| Evaluation of early administration of simvastatin in the prevention and treatment of delirium in critically ill patients undergoing mechanical ventilation (MoDUS): a randomised, double-blind, placebo-controlled trial. | Page, V. J. Casarin, A. Ely, E. W. Zhao, X. B. McDowell, C. Murphy, L. McAuley, D. F. | Lancet Respir Med | 2017 | |
| The effect of nonpharmacological training on delirium identification and intervention strategies of intensive care nurses. | Ozturk Birge, A. Tel Aydin, H. | Intensive Crit Care Nurs | 2017 |
Adult |
| Validation of the 6-Item Cognitive Impairment Test and the 4AT test for combined delirium and dementia screening in older Emergency Department attendees. | O'Sullivan, D. Brady, N. Manning, E. O'Shea, E. O'Grady, S. O. ' Regan N Timmons, S. | Age & Ageing | 2017 |
delirium |
| Risk factors for delirium after cardiac surgery: a historical cohort study outlining the influence of cardiopulmonary bypass. | O'Neal, J. B. Billings, F. T. th Liu, X. Shotwell, M. S. Liang, Y. Shah, A. S. Ehrenfeld, J. M. Wanderer, J. P. Shaw, A. D. | Can J Anaesth | 2017 |