What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- A call to action for delirium research: Meta-analysis and regression of delirium associated mortality
- Authors
- Aung Thein, M. Z. Pereira, J. V. Nitchingham, A. Caplan, G. A.
- Year
- 2020
- Journal
- BMC Geriatr
- Abstract
BACKGROUND: Delirium is an extremely common hospital complication. No study to date has assessed whether a priori defined covariates; type of hospital setting and year of study publication, influence the relationship between delirium and mortality. This is also the first study to examine the longitudinal trend of delirium-associated mortality over recent decades, to analyse the trajectory of our efforts in combating this disease. METHODS: MEDLINE, EMBASE and PsycINFO, were searched from January 1981 to May 2018 for English-language primary articles. Rigorous title and abstract screen and full-text screen were conducted independently by two reviewers. This paper adhered to MOOSE guidelines. Data was extracted independently by one reviewer using standardised data-collection sheets, with a separate reviewer verifying for accuracy. The quality of included studies was assessed using the Newcastle-Ottawa Quality Assessment Scale. Unadjusted effect sizes and event counts were analysed with a random effects model in primary meta-analysis and meta-regression, whereas a mixed effect model was used in secondary sub-group analysis. Mortality data at longest follow-up and cumulative mortality (hospital mortality combined with mortality at longest follow-up) data were analysed. RESULTS: As part of a larger project, 446 of 6790 articles were retrieved, including 71 studies that measured mortality. Our results demonstrate that elderly inpatients with delirium had significantly greater odds of mortality (OR 3.18 [95%CI: 2.73, 3.70]) compared to non-delirious controls. Patients with delirium in the ICU had the highest odds for mortality (OR: 7.09 [95%CI: 3.60, 14.0]); double the risk compared to the average. Curiously, despite advancements in delirium research, delirium associated in-hospital odds of mortality has not changed in 30 years. CONCLUSION: This is the largest meta-analysis to confirm the association between delirium and mortality, in older (age ≥ 65) hospital inpatients. The current meta-analysis highlights the significant odds of mortality after an episode of delirium, and these odds are much higher for ICU patients. However, in contrast to other medical conditions that have seen a decrease in associated mortality over the past few decades, delirium associated mortality remains unchanged. These findings underscore the urgent need for better delirium treatments. PROSPERO Registration Number: CRD42018098627, https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=98627.
- PMID
- Keywords
Aged
Delirium/diagnosis
Humans
Acute confusion
Death
Delirium
Mortality
Prognosis
- Page(s)
- 325
- Volume
- 20
- Issue
- 1
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Effect of Delirium and Other Major Complications on Outcomes After Elective Surgery in Older Adults. | Gleason LJ, Schmitt EM, Kosar CM, Tabloski P, Saczynski JS, Robinson T, Cooper Z, Rogers SO, Jones RN, Marcantonio ER, Inouye SK | JAMA surgery | 2015 | |
| Intraoperative Electroencephalogram Suppression Predicts Postoperative Delirium. | Fritz BA, Kalarickal PL, Maybrier HR, Muench MR, Dearth D, Chen Y, Escallier KE, Ben Abdallah A, Lin N, Avidan MS | Anesthesia and analgesia | 2016 | |
| Preliminary development of an ultrabrief two-item bedside test for delirium. | Fick DM, Inouye SK, Guess J, Ngo LH, Jones RN, Saczynski JS, Marcantonio ER | Journal of hospital medicine | 2015 | |
| The Frequency, Characteristics, and Outcomes Among Cancer Patients With Delirium Admitted to an Acute Palliative Care Unit. | de la Cruz M, Ransing V, Yennu S, Wu J, Liu D, Reddy A, Delgado-Guay M, Bruera E | The oncologist | 2015 | |
| Partial and No Recovery from Delirium in Older Hospitalized Adults: Frequency and Baseline Risk Factors. | Cole MG, Bailey R, Bonnycastle M, McCusker J, Fung S, Ciampi A, Belzile E, Bai C | Journal of the American Geriatrics Society | 2015 |
Activities of Daily Living, Aged, Aged, 80 and over, Delirium, physiopathology, Dementia, complications, Female, Follow-Up Studies, Humans, Inpatients, Intelligence Tests, Male, Prognosis, Risk Factors |
| Short-Form Mini Nutritional Assessment as a useful method of predicting the development of postoperative delirium in elderly patients undergoing orthopedic surgery. | Chu CS, Liang CK, Chou MY, Lin YT, Hsu CJ, Chou PH, Chu CL | General hospital psychiatry | 2016 | |
| Under-detection of delirium and impact of neurocognitive deficits on in-hospital mortality among acute geriatric and medical wards. | Bellelli G, Nobili A, Annoni G, Morandi A, Djade CD, Meagher DJ, Maclullich AM, Davis D, Mazzone A, Tettamanti M, Mannucci PM, | European journal of internal medicine | 2015 | |
| Timing Is Critical in Determining the Association Between Delirium and S100 Calcium-Binding Protein B. | Beishuizen SJ, Scholtens RM, Vellekoop AE, Vrouenraets BC, Westhoff D, van de Beek D, de Rooij SE, van Munster BC | Journal of the American Geriatrics Society | 2015 | |
| Delirium monitoring and patient outcomes in a general intensive care unit. | Andrews L, Silva SG, Kaplan S, Zimbro K | American journal of critical care : an official publication, American Association of Critical-Care Nurses | 2015 |
Aged, Aged, 80 and over, Delirium, diagnosis, Female, Humans, Intensive Care, methods, Intensive Care Units, Length of Stay, statistics & numerical data, Male, Neuropsychological Tests, statistics & numerical data, Nursing Assessment, methods, Outcome and Process Assessment (Health Care), statistics & numerical data, Questionnaires, Respiration, Artificial, statistics & numerical data, Retrospective Studies |
| Evaluating attention in delirium: A comparison of bedside tests of attention. | Adamis D, Meagher D, Murray O, O'Neill D, O'Mahony E, Mulligan O, McCarthy G | Geriatrics & gerontology international | 2016 | |
| Prevention of delirium (POD) for older people in hospital: study protocol for a randomised controlled feasibility trial. | Young J, Cheater F, Collinson M, Fletcher M, Forster A, Godfrey M, Green J, Anwar S, Hartley S, Hulme C, Inouye SK, Meads D, Santorelli G, Siddiqi N, Smith J, Teale E, Farrin AJ | Trials | 2015 | |
| Intraoperative hypotension and delirium after on-pump cardiac surgery. | Wesselink EM, Kappen TH, van Klei WA, Dieleman JM, van Dijk D, Slooter AJ | British journal of anaesthesia | 2015 |
Adult, Aged, Aged, 80 and over, Antiemetics, administration & dosage, Cardiac Surgical Procedures, Cohort Studies, Delirium, epidemiology, Dexamethasone, administration & dosage, Female, Humans, Hypotension, epidemiology, Intraoperative Complications, epidemiology, Male, Middle Aged, Postoperative Complications, epidemiology, Young Adult |
| Cytokines and Postoperative Delirium in Older Patients Undergoing Major Elective Surgery. | Vasunilashorn SM, Ngo L, Inouye SK, Libermann TA, Jones RN, Alsop DC, Guess J, Jastrzebski S, McElhaney JE, Kuchel GA, Marcantonio ER | The journals of gerontology. Series A, Biological sciences and medical sciences | 2015 | |
| Is preoperative state anxiety a risk factor for postoperative delirium among elderly hip fracture patients? | Van Grootven B, Detroyer E, Devriendt E, Sermon A, Deschodt M, Flamaing J, Dubois C, Milisen K | Geriatrics & gerontology international | 2016 | |
| Prevalence, course and factors associated with delirium in elderly patients with advanced cancer: a longitudinal observational study. | Uchida M, Okuyama T, Ito Y, Nakaguchi T, Miyazaki M, Sakamoto M, Kamiya T, Sato S, Takeyama H, Joh T, Meagher D, Akechi T | Japanese journal of clinical oncology | 2015 | |
| Incidence and risk factors of postoperative delirium in elderly patients who underwent laparoscopic surgery for colorectal cancer. | Tei M, Wakasugi M, Kishi K, Tanemura M, Akamatsu H | International journal of colorectal disease | 2016 | |
| Factors predicting perioperative delirium and acute exacerbation of behavioral and psychological symptoms of dementia based on admission data in elderly patients with proximal femoral fracture: A retrospective study. | Tanaka T | Geriatrics & gerontology international | 2016 | |
| Impact of surgical approach on postoperative delirium in elderly patients undergoing gastrectomy: laparoscopic versus open approaches. | Shin YH, Kim DK, Jeong HJ | Korean journal of anesthesiology | 2015 | |
| Frequency and Outcome of Neuroleptic Rotation in the Management of Delirium in Patients with Advanced Cancer. | Shin SH, Hui D, Chisholm G, Kang JH, Allo J, Williams J, Bruera E | Cancer research and treatment : official journal of Korean Cancer Association | 2015 | |
| Prognostic Significance of Postoperative Subsyndromal Delirium. | Shim J, DePalma G, Sands LP, Leung JM | Psychosomatics | 2015 | |
| Relationship between cobalamin deficiency and delirium in elderly patients undergoing cardiac surgery. | Sevuk U, Baysal E, Ay N, Altas Y, Altindag R, Yaylak B, Alp V, Demirtas E | Neuropsychiatric disease and treatment | 2015 | |
| Performance of the Delirium Rating Scale-Revised-98 Against Different Delirium Diagnostic Criteria in a Population With a High Prevalence of Dementia. | Sepulveda E, Franco JG, Trzepacz PT, Gaviria AM, Viñuelas E, Palma J, Ferré G, Grau I, Vilella E | Psychosomatics | 2015 | |
| Prognostic value and risk factors of delirium in emergency patients with decompensated heart failure. | Rizzi MA, Torres Bonafonte OH, Alquezar A, Herrera Mateo S, Piñera P, Puig M, Benito S, Ruiz D | Journal of the American Medical Directors Association | 2015 | |
| Risk Factors and Outcomes for Postoperative Delirium after Major Surgery in Elderly Patients. | Raats JW, van Eijsden WA, Crolla RM, Steyerberg EW, van der Laan L | PloS one | 2015 | |
| The Language of Delirium: Keywords for Identifying Delirium from Medical Records. | Puelle MR, Kosar CM, Xu G, Schmitt E, Jones RN, Marcantonio ER, Cooper Z, Inouye SK, Saczynski JS | Journal of gerontological nursing | 2015 |
Aged, Aged, 80 and over, Cohort Studies, Delirium, diagnosis, Electronic Health Records, Female, Humans, Male, Terminology as Topic |
| Delirium is a robust predictor of morbidity and mortality among critically ill patients treated in the cardiac intensive care unit. | Pauley E, Lishmanov A, Schumann S, Gala GJ, van Diepen S, Katz JN | American heart journal | 2015 |
APACHE, Acute Kidney Injury, epidemiology, Age Factors, Aged, Cohort Studies, Comorbidity, Critical Illness, Delirium, epidemiology, Female, Heart Arrest, epidemiology, Heart Diseases, epidemiology, Heart Valve Diseases, epidemiology, Humans, Intensive Care Units, Length of Stay, Linear Models, Logistic Models, Male, Middle Aged, Multivariate Analysis, Myocardial Infarction, epidemiology, North Carolina, epidemiology, Prevalence, Prognosis, Respiratory Insufficiency, epidemiology, Sepsis, epidemiology, Severity of Illness Index |
| Return to work six months after burn: A prospective study at the Helsinki Burn Center. | Palmu R, Partonen T, Suominen K, Vuola J, Isometsä E | Burns : journal of the International Society for Burn Injuries | 2015 | |
| Delirium, how does it end? Mortality as an outcome in older medical inpatients. | Muresan ML, Adamis D, Murray O, O'Mahony E, McCarthy G | International journal of geriatric psychiatry | 2015 | |
| Delirium superimposed on dementia: A quantitative and qualitative evaluation of informal caregivers and health care staff experience. | Morandi A, Lucchi E, Turco R, Morghen S, Guerini F, Santi R, Gentile S, Meagher D, Voyer P, Fick DM, Schmitt EM, Inouye SK, Trabucchi M, Bellelli G | Journal of psychosomatic research | 2015 |
Caregivers, psychology, Cohort Studies, Delirium, nursing, Dementia, nursing, Female, Humans, Male, Middle Aged, Patient Care Team, standards, Prospective Studies, Surveys and Questionnaires |
| Delirium superimposed on dementia: A quantitative and qualitative evaluation of patient experience. | Morandi A, Lucchi E, Turco R, Morghen S, Guerini F, Santi R, Gentile S, Meagher D, Voyer P, Fick D, Schmitt EM, Inouye SK, Trabucchi M, Bellelli G | Journal of psychosomatic research | 2015 | |
| Delirium and Circadian Rhythm of Melatonin During Weaning From Mechanical Ventilation: An Ancillary Study of a Weaning Trial. | Mekontso Dessap A, Roche-Campo F, Launay JM, Charles-Nelson A, Katsahian S, Brun-Buisson C, Brochard L | Chest | 2015 |
Aged, Ancillary Services, Hospital, Circadian Rhythm, Delirium, etiology, Female, Follow-Up Studies, Humans, Intensive Care Units, Male, Melatonin, analogs & derivatives, Middle Aged, Respiration, Artificial, Time Factors, Ventilator Weaning, methods |
| Chemotherapeutic drugs that penetrate the blood-brain barrier affect the development of hyperactive delirium in cancer patients. | Matsuoka H, Yoshiuchi K, Koyama A, Otsuka M, Nakagawa K | Palliative & supportive care | 2015 | |
| Patient factors associated with 30-day morbidity, mortality, and length of stay after surgery for subdural hematoma: a study of the American College of Surgeons National Surgical Quality Improvement Program. | Lukasiewicz AM, Grant RA, Basques BA, Webb ML, Samuel AM, Grauer JN | Journal of neurosurgery | 2015 | |
| Preoperative Sleep Disruption and Postoperative Delirium. | Leung JM, Sands LP, Newman S, Meckler G, Xie Y, Gay C, Lee K | Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine | 2015 | |
| Anesthesiologic regimen and intraoperative delirium in deep brain stimulation surgery for Parkinson's disease. | Lange M, Zech N, Seemann M, Janzen A, Halbing D, Zeman F, Doenitz C, Rothenfusser E, Hansen E, Brawanski A, Schlaier J | Journal of the neurological sciences | 2015 | |
| Predicting outcome in older hospital patients with delirium: a systematic literature review. | Jackson TA, Wilson D, Richardson S, Lord JM | International journal of geriatric psychiatry | 2016 | |
| Enhancing Cognitive Aging: Clinical Highlights of a Report From the Institute of Medicine. | Inouye SK | Annals of internal medicine | 2015 | |
| Risk factors associated with postoperative delirium after surgery for oral cancer. | Hasegawa T, Saito I, Takeda D, Iwata E, Yonezawa N, Kakei Y, Sakakibara A, Akashi M, Minamikawa T, Komori T | Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery | 2015 | |
| The Diagnostic Performance of the Richmond Agitation Sedation Scale for Detecting Delirium in Older Emergency Department Patients. | Han JH, Vasilevskis EE, Schnelle JF, Shintani A, Dittus RS, Wilson A, Ely EW | Academic emergency medicine : official journal of the Society for Academic Emergency Medicine | 2015 |
Age Factors, Aged, Aged, 80 and over, Clinical Protocols, Consciousness, Delirium, diagnosis, Emergency Service, Hospital, organization & administration, Female, Humans, Male, Prospective Studies, Reproducibility of Results, Sensitivity and Specificity |
| Risk factors and clinical aspects of delirium in elderly hospitalized patients in Iran. | Foroughan M, Delbari A, Said SE, AkbariKamrani AA, Rashedi V, Zandi T | Aging clinical and experimental research | 2016 | |
| The interface between delirium and dementia in elderly adults. | Fong TG, Davis D, Growdon ME, Albuquerque A, Inouye SK | The Lancet. Neurology | 2015 | |
| Predictors of Long-Term Mortality in Oldest Old Patients (90+) Hospitalized to Medical Wards via the Emergency Department: The SAFES Cohort. | de Boissieu P, Mahmoudi R, Hentzien M, Toquet S, Novella JL, Blanchard F, Jolly D, Dramé M | The journal of nutrition, health & aging | 2015 | |
| Exogenous Melatonin for Delirium Prevention: a Meta-analysis of Randomized Controlled Trials. | Chen S, Shi L, Liang F, Xu L, Desislava D, Wu Q, Zhang J | Molecular neurobiology | 2015 | |
| Efficacy of Non-Pharmacological Interventions to Prevent and Treat Delirium in Older Patients: A Systematic Overview. The SENATOR project ONTOP Series. | Abraha I, Trotta F, Rimland JM, Cruz-Jentoft A, Lozano-Montoya I, Soiza RL, Pierini V, Dessì Fulgheri P, Lattanzio F, O'Mahony D, Cherubini A | PloS one | 2015 | |
| Effect of dexmedetomidine on preventing agitation and delirium after microvascular free flap surgery: a randomized, double-blind, control study. | Yang X, Li Z, Gao C, Liu R | Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons | 2015 | |
| Intraoperative tight glucose control using hyperinsulinemic normoglycemia increases delirium after cardiac surgery. | Saager L, Duncan AE, Yared JP, Hesler BD, You J, Deogaonkar A, Sessler DI, Kurz A | Anesthesiology | 2015 |
Aged, Aged, 80 and over, Blood Glucose, analysis, Cardiac Surgical Procedures, adverse effects, Confusion, psychology, Delirium, chemically induced, Double-Blind Method, Female, Glucose Clamp Technique, Humans, Hyperinsulinism, blood, Intraoperative Care, adverse effects, Male, Middle Aged, Neuropsychological Tests, Postoperative Complications, chemically induced |
| Association between pre-hospital vitamin D status and hospital-acquired new-onset delirium. | Quraishi SA, Litonjua AA, Elias KM, Gibbons FK, Giovannucci E, Camargo CA, Christopher KB | The British journal of nutrition | 2015 | |
| Effect Estimation of an Innovative Nursing Intervention to Improve Delirium among Home-Dwelling Older Adults: A Randomized Controlled Pilot Trial. | Verloo H, Goulet C, Morin D, von Gunten A | Dementia and geriatric cognitive disorders extra | 2015 | |
| Identifying phenomenological differences and recovery of cognitive and non-cognitive symptomatology among delirium superimposed upon dementia patients (DsD) versus those without dementia (DaD) in an acute geriatric care setting. | Chong E, Tay L, Chong MS | International psychogeriatrics / IPA | 2015 | |
| Health economic implications of perioperative delirium in older patients after surgery for a fragility hip fracture. | Zywiel MG, Hurley RT, Perruccio AV, Hancock-Howard RL, Coyte PC, Rampersaud YR | The Journal of bone and joint surgery. American volume | 2015 |
Aged, Aged, 80 and over, Case-Control Studies, Costs and Cost Analysis, Delirium, economics, Female, Fractures, Spontaneous, economics, Hip Fractures, economics, Humans, Length of Stay, economics, Male, Perioperative Care, economics, Postoperative Complications, economics, Propensity Score, Prospective Studies |
| The Bromhead Care Home Service: the impact of a service for care home residents with dementia on hospital admission and dying in preferred place of care. | Garden G, Green S, Pieniak S, Gladman J | Clinical medicine (London, England) | 2016 | |
| The Association Between Preoperative Frailty and Postoperative Delirium After Cardiac Surgery. | Brown CH, Max L, LaFlam A, Kirk L, Gross A, Arora R, Neufeld K, Hogue CW, Walston J, Pustavoitau A | Anesthesia and analgesia | 2016 | |
| Antipsychotic Drug Use and Screening for Delirium in Mechanically Ventilated Patients in Canadian Intensive Care Units: An Observational Study. | Thiboutot Z, Perreault MM, Williamson DR, Rose L, Mehta S, Guenette MD, Cook D, Burry L | The Canadian journal of hospital pharmacy | 2016 | |
| Abnormal Mini-Cog Is Associated with Higher Risk of Complications and Delirium in Geriatric Patients with Fracture. | Heng M, Eagen CE, Javedan H, Kodela J, Weaver MJ, Harris MB | The Journal of bone and joint surgery. American volume | 2016 | |
| DELirium Prediction Based on Hospital Information (Delphi) in General Surgery Patients. | Kim MY, Park UJ, Kim HT, Cho WH | Medicine | 2016 | |
| Serum Anticholinergic Activity and Cognitive and Functional Adverse Outcomes in Older People: A Systematic Review and Meta-Analysis of the Literature. | Salahudeen MS, Chyou TY, Nishtala PS | PloS one | 2016 | |
| Impact of length of red blood cells transfusion on postoperative delirium in elderly patients undergoing hip fracture surgery: A cohort study. | Zhang ZY, Gao DP, Yang JJ, Sun XR, Zhang H, Hu J, Fang ZY, Yang JJ, Ji MH | Injury | 2016 | |
| Nursing intervention versus usual care to improve delirium among home-dwelling older adults receiving homecare after hospitalization: feasibility and acceptability of a Randomized Controlled Trail. | Verloo H, Goulet C, Morin D, von Gunten A | BMC nursing | 2016 | |
| Use of medications that antagonize mediators of inflammatory responses may reduce the risk of delirium in older adults: a nested case-control study. | Cole MG, McCusker J, Wilchesky M, Voyer P, Monette J, Champoux N, Vu M, Ciampi A, Belzile E | International journal of geriatric psychiatry | 2016 | |
| Frequency of full, partial and no recovery from subsyndromal deliriumin older hospital inpatients. | Cole MG, Bailey R, Bonnycastle M, McCusker J, Fung S, Ciampi A, Belzile E | International journal of geriatric psychiatry | 2016 | |
| Preventing ICU Subsyndromal Delirium Conversion to Delirium With Low-Dose IV Haloperidol: A Double-Blind, Placebo-Controlled Pilot Study. | Al-Qadheeb NS, Skrobik Y, Schumaker G, Pacheco MN, Roberts RJ, Ruthazer RR, Devlin JW | Critical care medicine | 2016 | |
| Postoperative plasma 8-iso-prostaglandin F2α levels are associated with delirium and cognitive dysfunction in elderly patients after hip fracture surgery. | Zheng YB, Ruan GM, Fu JX, Su ZL, Cheng P, Lu JZ | Clinica chimica acta; international journal of clinical chemistry | 2016 | |
| Profiles of delirium and the clinical outcomes of patients who underwent coronary artery bypass grafting: a prospective study from China. | Zhang W, Hu W, Shen M, Ye X, Huang Y, Sun Y | Journal of clinical nursing | 2016 |
Adult, Aged, Aged, 80 and over, China, Coronary Artery Bypass, adverse effects, Coronary Artery Disease, psychology, Delirium, diagnosis, Female, Humans, Length of Stay, Male, Middle Aged, Outcome Assessment (Health Care), Prospective Studies |
| Risk factors for postoperative delirium following hip fracture repair in elderly patients: a systematic review and meta-analysis. | Yang Y, Zhao X, Dong T, Yang Z, Zhang Q, Zhang Y | Aging clinical and experimental research | 2017 | |
| RADAR: A Measure of the Sixth Vital Sign? | Voyer P, Champoux N, Desrosiers J, Landreville P, McCusker J, Monette J, Savoie M, Carmichael PH, Richard H, Richard S | Clinical nursing research | 2016 | |
| Association between frailty and delirium in older adult patients discharged from hospital. | Verloo H, Goulet C, Morin D, von Gunten A | Clinical interventions in aging | 2016 | |
| Psychometric properties and feasibility of instruments for the detection of delirium in older hospitalized patients: a systematic review. | van Velthuijsen EL, Zwakhalen SM, Warnier RM, Mulder WJ, Verhey FR, Kempen GI | International journal of geriatric psychiatry | 2016 | |
| The patient's perception of a delirium: A qualitative research in a Belgian intensive care unit. | Van Rompaey B, Van Hoof A, van Bogaert P, Timmermans O, Dilles T | Intensive & critical care nursing : the official journal of the British Association of Critical Care Nurses | 2016 | |
| Biomarkers of Delirium in a Low-Risk Community-Acquired Pneumonia-Induced Sepsis. | Tomasi CD, Vuolo F, Generoso J, Soares M, Barichello T, Quevedo J, Ritter C, Dal-Pizzol F | Molecular neurobiology | 2016 | |
| How to advance prediction of postoperative delirium? A secondary analysis comparing three methods for very early assessment of elderly patients after surgery and early prediction of delirium. | Stukenberg S, Franck M, Spies CD, Neuner B, Myers I, Radtke FM | Minerva anestesiologica | 2016 | |
| A Flipped Classroom Approach to Improving the Quality of Delirium Care Using an Interprofessional Train-the-Trainer Program. | Sockalingam S, James SL, Sinyi R, Carroll A, Laidlaw J, Yanofsky R, Sheehan K | The Journal of continuing education in the health professions | 2016 | |
| Reduced Cerebral Perfusion Pressure during Lung Transplant Surgery Is Associated with Risk, Duration, and Severity of Postoperative Delirium. | Smith PJ, Blumenthal JA, Hoffman BM, Rivelli SK, Palmer SM, Davis RD, Mathew JP | Annals of the American Thoracic Society | 2016 | |
| Depressive Symptoms and Risk of Postoperative Delirium. | Smith PJ, Attix DK, Weldon BC, Monk TG | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry | 2016 | |
| Dynamic light application therapy to reduce the incidence and duration of delirium in intensive-care patients: a randomised controlled trial. | Simons KS, Laheij RJ, van den Boogaard M, Moviat MA, Paling AJ, Polderman FN, Rozendaal FW, Salet GA, van der Hoeven JG, Pickkers P, de Jager CP | The Lancet. Respiratory medicine | 2016 | |
| Interventions for preventing delirium in hospitalised non-ICU patients. | Siddiqi N, Harrison JK, Clegg A, Teale EA, Young J, Taylor J, Simpkins SA | The Cochrane database of systematic reviews | 2016 | |
| Validation of the Sour Seven Questionnaire for screening delirium in hospitalized seniors by informal caregivers and untrained nurses. | Shulman RW, Kalra S, Jiang JZ | BMC geriatrics | 2016 |
Aged, Aged, 80 and over, Caregivers, psychology, Delirium, diagnosis, Family, psychology, Female, Geriatric Assessment, methods, Hospitalization, Humans, Male, Mass Screening, methods, Nurse’s Role, psychology, Pilot Projects, Surveys and Questionnaires, standards |
| Efficacy and safety of haloperidol for in-hospital delirium prevention and treatment: A systematic review of current evidence. | Schrijver EJ, de Graaf K, de Vries OJ, Maier AB, Nanayakkara PW | European journal of internal medicine | 2016 | |
| Systematic review and meta-analysis of risk factors for postoperative delirium among older patients undergoing gastrointestinal surgery. | Scholz AF, Oldroyd C, McCarthy K, Quinn TJ, Hewitt J | The British journal of surgery | 2016 | |
| Validation of a Delirium Risk Assessment Using Electronic Medical Record Information. | Rudolph JL, Doherty K, Kelly B, Driver JA, Archambault E | Journal of the American Medical Directors Association | 2016 | |
| The implementation of a nonpharmacologic protocol to prevent intensive care delirium. | Rivosecchi RM, Kane-Gill SL, Svec S, Campbell S, Smithburger PL | Journal of critical care | 2016 | |
| Delirium superimposed on dementia: a survey of delirium specialists shows a lack of consensus in clinical practice and research studies. | Richardson S, Teodorczuk A, Bellelli G, Davis DH, Neufeld KJ, Kamholz BA, Trabucchi M, MacLullich AM, Morandi A | International psychogeriatrics / IPA | 2016 | |
| Effect of Dexmedetomidine Added to Standard Care on Ventilator-Free Time in Patients With Agitated Delirium: A Randomized Clinical Trial. | Reade MC, Eastwood GM, Bellomo R, Bailey M, Bersten A, Cheung B, Davies A, Delaney A, Ghosh A, van Haren F, Harley N, Knight D, McGuiness S, Mulder J, O'Donoghue S, Simpson N, Young P, , | JAMA | 2016 |
Aged, Australia, Delirium, complications, Dexmedetomidine, administration & dosage, Double-Blind Method, Female, Humans, Hypnotics and Sedatives, administration & dosage, Male, Middle Aged, New Zealand, Proportional Hazards Models, Psychomotor Agitation, drug therapy, Respiration, Artificial, statistics & numerical data, Time Factors, Treatment Outcome, Ventilator Weaning, contraindications |
| Functional interrelationship of brain aging and delirium. | Rapazzini P | Aging clinical and experimental research | 2016 | |
| Delirium risk stratification in consecutive unselected admissions to acute medicine: validation of externally derived risk scores. | Pendlebury ST, Lovett N, Smith SC, Cornish E, Mehta Z, Rothwell PM | Age and ageing | 2016 | |
| A Family-Focused Delirium Educational Initiative With Practice and Research Implications. | Paulson CM, Monroe T, McDougall GJ, Fick DM | Gerontology & geriatrics education | 2016 | |
| How do doctors and nurses manage delirium in intensive care units? A qualitative study using focus groups. | Palacios-Ceña D, Cachón-Pérez JM, Martínez-Piedrola R, Gueita-Rodriguez J, Perez-de-Heredia M, Fernández-de-Las-Peñas C | BMJ open | 2016 | |
| The role of anesthesia in the prevention of postoperative delirium: a systematic review. | Orena EF, King AB, Hughes CG | Minerva anestesiologica | 2016 | |
| Postoperative Delirium in Elderly Patients Undergoing Hip Fracture Surgery in the Sugammadex Era: A Retrospective Study. | Oh CS, Rhee KY, Yoon TG, Woo NS, Hong SW, Kim SH | BioMed research international | 2016 | |
| High prolactin levels are associated with more delirium in septic patients. | Nguyen DN, Huyghens L, Schiettecatte J, Smitz J, Vincent JL | Journal of critical care | 2016 | |
| Antipsychotic Medication for Prevention and Treatment of Delirium in Hospitalized Adults: A Systematic Review and Meta-Analysis. | Neufeld KJ, Yue J, Robinson TN, Inouye SK, Needham DM | Journal of the American Geriatrics Society | 2016 | |
| Depressive Symptoms Before, During, and After Delirium: A Literature Review. | Nelson S, Rustad JK, Catalano G, Stern TA, Kozel FA | Psychosomatics | 2016 | |
| Rosuvastatin versus placebo for delirium in intensive care and subsequent cognitive impairment in patients with sepsis-associated acute respiratory distress syndrome: an ancillary study to a randomised controlled trial. | Needham DM, Colantuoni E, Dinglas VD, Hough CL, Wozniak AW, Jackson JC, Morris PE, Mendez-Tellez PA, Ely EW, Hopkins RO | The Lancet. Respiratory medicine | 2016 | |
| Cyproheptadine for the Prevention of Postoperative Delirium: A Pilot Study. | Mohammadi M, Ahmadi M, Khalili H, Cheraghchi H, Arbabi M | The Annals of pharmacotherapy | 2016 | |
| Delirium after surgical and transcatheter aortic valve replacement is associated with increased mortality. | Maniar HS, Lindman BR, Escallier K, Avidan M, Novak E, Melby SJ, Damiano MS, Lasala J, Quader N, Rao RS, Lawton J, Moon MR, Helsten D, Pasque MK, Damiano RJ, Zajarias A | The Journal of thoracic and cardiovascular surgery | 2016 | |
| The Efficacy of Earplugs as a Sleep Hygiene Strategy for Reducing Delirium in the ICU: A Systematic Review and Meta-Analysis. | Litton E, Carnegie V, Elliott R, Webb SA | Critical care medicine | 2016 | |
| Delirium in critical care: a study of incidence, prevalence, and associated factors in the tertiary care hospital of older Thai adults. | Limpawattana P, Panitchote A, Tangvoraphonkchai K, Suebsoh N, Eamma W, Chanthonglarng B, Tiamkao S | Aging & mental health | 2016 | |
| Comparison of cognitive and neuropsychiatric profiles in hospitalised elderly medical patients with delirium, dementia and comorbid delirium-dementia. | Leonard M, McInerney S, McFarland J, Condon C, Awan F, O'Connor M, Reynolds P, Meaney AM, Adamis D, Dunne C, Cullen W, Trzepacz PT, Meagher DJ | BMJ open | 2016 | |
| Identification of sub-groups in acutely ill elderly patients with delirium: a cluster analysis. | Lagarto L, Cerejeira J | International psychogeriatrics / IPA | 2016 | |
| Development and validation of the Thai version of the 4 'A's Test for delirium screening in hospitalized elderly patients with acute medical illnesses. | Kuladee S, Prachason T | Neuropsychiatric disease and treatment | 2016 | |
| Delirium is a risk factor for further cognitive decline in cognitively impaired hip fracture patients. | Krogseth M, Watne LO, Juliebø V, Skovlund E, Engedal K, Frihagen F, Wyller TB | Archives of gerontology and geriatrics | 2016 |