What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Prevention of dexmedetomidine on postoperative delirium and early postoperative cognitive dysfunction in elderly patients undergoing hepatic lobectomy
- Authors
- Tang, Y. Wang, Y. Kong, G. Zhao, Y. Wei, L. Liu, J.
- Year
- 2022
- Journal
- Zhong Nan Da Xue Xue Bao Yi Xue Ban
- Abstract
OBJECTIVES: Postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) are common operative neurocognitive disorders, which places a heavy burden on patients, families and society. Therefore, it is very important to search for preventive drugs. Previous studies have demonstrated that perioperative use of dexmedetomidine resulted in a decrease the incidence of POD and POCD. But the specific effect of dexmedetomidine on elderly patients undergoing hepatic lobectomy and its potential mechanism are not clear. This study aims to evaluate the efficacy of intraoperative use of dexmedetomidine on preventing POD and POCD in elderly patients undergoing hepatic lobectomy and the influence on the balance between proinflammation and anti-inflammation. METHODS: This trial was designed as a single-center, prospective, randomized, controlled study. One hundred and twenty hospitalized patients from January 2019 to December 2020, aged 60-80 years old with American Society of Anesthesiologists (ASA) II-III and scheduled for hepatic lobectomy, were randomly allocated into 3 groups (n=40) using a random number table: A C group, a Dex1 group, and a Dex2 group. After anesthesia induction, saline in the C group, dexmedetomidine [0.3 μg/(kg·h)] in the Dex1 group, and dexmedetomidine [0.6 μg/(kg·h)] in the Dex2 group were infused until the end of operation. The incidences of hypotension and bradycardia were compared among the 3 groups. Confusion Assessment Method (CAM) for assessing POD and Mini Mental State Examination (MMSE) for evaluating POCD were recorded and venous blood samples were obtained for the determination of neuron specific enolase (NSE), TNF-α, IL-1β, and IL-10 at the different time below: the time before anesthesia (T0), and the first day (T1), the third day (T2), the fifth day (T3), and the seventh day (T4) after operation. RESULTS: Compared with the C group, the incidences of bradycardia in the Dex1 group or the Dex2 group increased (both P<0.05) and there was no difference in hypotension in the Dex1 group or the Dex2 group (both P>0.05). The incidences of POD in the C group, the Dex1 group, and the Dex2 group were 22.5%, 5.0%, and 7.5%, respectively. The incidences of POD in the Dex1 group or the Dex2 group declined significantly as compared to the C group (both P<0.05). However, there is no difference in the incidence of POD between the Dex1 group and the Dex2 group (P>0.05). The incidences of POCD in the C group, the Dex1 group, and the Dex2 group were 30.0%, 12.5%, and 10.0%, respectively. The incidences of POCD in the Dex1 group and the Dex2 group declined significantly as compared to the C group (both P<0.05). And no obvious difference was seen in the incidence of POCD in the Dex1 group and the Dex2 group (P>0.05). Compared with the C group, the level of TNF-α and IL-1β decreased and the level of IL-10 increased at each time points (from T1 to T4) in the Dex1 group and the Dex2 group (all P<0.05). Compared with the Dex1 group, the level of IL-1β at T2 and IL-10 from T1 to T3 elevated in the Dex2 group (all P<0.05). Compared with the T0, the concentrations of NSE in C group at each time points (from T1 to T4) and in the Dex1 group and the Dex2 group from T1 to T3 increased (all P<0.05). Compared with the C group, the level of NSE decreased from T1 to T4 in the Dex1 group and the Dex2 group (all P<0.05). CONCLUSIONS: Intraoperative dexmedetomidine infusion can reduce the incidence of POCD and POD in elderly patients undergoing hepatic lobectomy, and the protective mechanism appears to involve the down-regulation of TNF-α and IL-1β and upregulation of IL-10 expression, which lead to rebalance between proinflammation and anti-inflammation.
- PMID
- Keywords
Aged
Aged, 80 and over
Bradycardia
*Cognitive Dysfunction/etiology/prevention & control
*Delirium/drug therapy/epidemiology/prevention & control
*Dexmedetomidine/therapeutic use
Humans
*Hypotension/complications/drug therapy
Interleukin-10
Middle Aged
*Postoperative Cognitive Complications/prevention & control
Postoperative Complications/epidemiology
Prospective Studies
Tumor Necrosis Factor-alpha
dexmedetomidine
elderly patients
hepatic lobectomy
postoperative cognitive dysfunction
postoperative delirium
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords | |
|---|---|---|---|---|---|
| DEL-FINE: a new tool for assessing the delirogenic properties of drugs of relevance for European pharmacotherapy. | Böhmdorfer B, Rohleder S, Wawruch M, van der Cammen TJ, Frühwald T, Jagsch C, Janowitz SM, Nagano M, Petrovic M, Sommeregger U, Iglseder B | Zeitschrift fur Gerontologie und Geriatrie | 2016 |
Anticholinergic Syndrome, etiology, Delirium, chemically induced, Delphi Technique, Drug Therapy, standards, Europe, Expert Testimony, methods, Humans, Practice Guidelines as Topic |
|
| Consciousness, Functional networks and Delirium screening. | Eeles E, Burianova H, Pandy S, Pinsker D | Current aging science | 2016 | ||
| Delirium: A Survey of Healthcare Professionals' Knowledge, Beliefs, and Practices. | Sinvani L, Kozikowski A, Pekmezaris R, Akerman M, Wolf-Klein G | Journal of the American Geriatrics Society | 2016 | ||
| Low dose dexmedetomidine for the prophylaxis of perioperative ICU delirium-how much evidence is enough? | Reade MC | Journal of thoracic disease | 2016 | ||
| [Study of prevention and control of delirium in ventilated patients by simulating blockage of circadian rhythm with sedative in intensive care unit]. | Li J, Dong C, Zhang H, Zhang H, Song R, Yang Z, Feng F, Qi Y, Yang J | Zhonghua wei zhong bing ji jiu yi xue | 2016 |
Analgesics, Circadian Rhythm, Critical Care, Delirium, Dexmedetomidine, Fentanyl, Humans, Hypnotics and Sedatives, Intensive Care Units, Pain, Propofol, Prospective Studies, Respiration, Artificial |
|
| Effect of Cognitively Stimulating Activities on Symptom Management of Delirium Superimposed on Dementia: A Randomized Controlled Trial. | Kolanowski A, Fick D, Litaker M, Mulhall P, Clare L, Hill N, Mogle J, Boustani M, Gill D, Yevchak-Sillner A | Journal of the American Geriatrics Society | 2016 | ||
| Dexmedetomidine for prevention of delirium in elderly patients after non-cardiac surgery. | Karren EA, King AB, Hughes CG | Journal of thoracic disease | 2016 | ||
| Decreased Incidence of Postoperative Delirium in Robot-assisted Thoracoscopic Esophagectomy Compared With Open Transthoracic Esophagectomy. | Jeong DM, Kim JA, Ahn HJ, Yang M, Heo BY, Lee SH | Surgical laparoscopy, endoscopy & percutaneous techniques | 2016 | ||
| Delirium in the Neuro Intensive Care Unit. | Haymore JB, Patel N | Critical care nursing clinics of North America | 2016 |
Brief Psychiatric Rating Scale, Critical Care, Delirium, physiopathology, Humans, Intensive Care Units, Nursing Assessment, Pain Management |
|
| CE: Assessing and Managing Pain, Agitation, and Delirium in Hospitalized Older Adults. | Hartjes TM, Meece L, Horgas AL | The American journal of nursing | 2016 |
Aged, Delirium, diagnosis, Education, Continuing, Hospitalization, Humans, Pain Management, methods, Pain Measurement, methods, Psychomotor Agitation, diagnosis |
|
| The Search for Effective Delirium Treatment for Persons with Dementia in the Postacute-Care Setting. | Fong TG, Albuquerque A, Inouye SK | Journal of the American Geriatrics Society | 2016 | ||
| Postoperative Delirium After Liver Transplantation is Associated With Increased Length of Stay and Lower Survival in a Prospective Cohort. | Beckmann S, Schubert M, Burkhalter H, Dutkowski P, De Geest S | Progress in transplantation (Aliso Viejo, Calif.) | 2016 | ||
| Predicting Delirium in Older Patients Hospitalized for Community-Acquired Pneumonia. | Viscogliosi G, Chiriac IM, Braucci S, Terracina D, Andreozzi P, Ettorre E | Journal of the American Medical Directors Association | 2016 | ||
| Preoperative discussion with patients about delirium risk: are we doing enough? | Tomlinson JH, Partridge JS | Perioperative medicine (London, England) | 2016 | ||
| Development, Implementation, and Outcomes of a Delirium Protocol in the Surgical Trauma Intensive Care Unit. | Sullinger D, Gilmer A, Jurado L, Zimmerman LH, Steelman J, Gallagher A, Dupre T, Acquista E | The Annals of pharmacotherapy | 2016 | ||
| The role of the NADPH oxidase derived brain oxidative stress in the cocaine-related death associated with excited delirium: A literature review. | Schiavone S, Neri M, Mhillaj E, Pomara C, Trabace L, Turillazzi E | Toxicology letters | 2016 | ||
| Does this patient have delirium? | Salluh JI, Sharshar T, Kress JP | Intensive care medicine | 2016 | ||
| [Knowledge and implementation of the S3 guideline on delirium management in Germany]. | Saller T, V Dossow V, Hofmann-Kiefer K | Der Anaesthesist | 2016 | ||
| Arousal, Attention, and an Abundance of Opportunity to Advance Delirium Care. | Rudolph JL | Journal of the American Medical Directors Association | 2016 | ||
| Risk factors of post-operative delirium after elective vascular surgery in the elderly: A systematic review. | Raats JW, Steunenberg SL, de Lange DC, van der Laan L | International journal of surgery (London, England) | 2016 | ||
| Screening for delirium in specialist palliative care inpatient units: perceptions and outcomes. | Porteous A, Dewhurst F, Gray WK, Coulter P, Karandikar U, Kiltie R, Lowery L, MacCormick F, Paxton A, Pickard J, Rowley G, Vidrine J, Walmsley R, Waterfield K, Weiand D, Grogan E | International journal of palliative nursing | 2016 | ||
| Postoperative delirium: age and low functional reserve as independent risk factors. | Pinho C, Cruz S, Santos A, Abelha FJ | Journal of clinical anesthesia | 2016 | ||
| Delirium assessment in intensive care units: practices and perceptions of Turkish nurses. | Özsaban A, Acaroglu R | Nursing in critical care | 2016 | ||
| Nurses' and physicians' perceptions of Confusion Assessment Method for the intensive care unit for delirium detection: focus group study. | Oxenbøll-Collet M, Egerod I, Christensen V, Jensen J, Thomsen T | Nursing in critical care | 2016 | ||
| Post-anaesthetic emergence delirium in adults: incidence, predictors and consequences. | Munk L, Andersen G, Møller AM | Acta anaesthesiologica Scandinavica | 2016 | ||
| The Diagnosis of Delirium Superimposed on Dementia: An Emerging Challenge. | Morandi A, Davis D, Bellelli G, Arora RC, Caplan GA, Kamholz B, Kolanowski A, Fick DM, Kreisel S, MacLullich A, Meagher D, Neufeld K, Pandharipande PP, Richardson S, Slooter AJ, Taylor JP, Thomas C, Tieges Z, Teodorczuk A, Voyer P, Rudolph JL | Journal of the American Medical Directors Association | 2017 | ||
| Revisiting DLB Diagnosis: A Consideration of Prodromal DLB and of the Diagnostic Overlap With Alzheimer Disease. | McKeith I, Taylor JP, Thomas A, Donaghy P, Kane J | Journal of geriatric psychiatry and neurology | 2016 | ||
| Underreporting of Delirium in Statewide Claims Data: Implications for Clinical Care and Predictive Modeling. | McCoy TH, Snapper L, Stern TA, Perlis RH | Psychosomatics | 2016 | ||
| [Delusion versus delirium]. | Martínez-Velilla N, Franco JG, Molina Amaya CM | Medicina clínica | 2016 | ||
| [The recognition and diagnosis of delirium in elderly people in intensive care unit]. | Li QD, Wan XY | Zhonghua nei ke za zhi | 2016 | ||
| Cancer patients with delirium in the emergency department: A frequent and distressing problem that calls for better assessment. | Lawlor PG | Cancer | 2016 | ||
| Routine use of antipsychotics to prevent or treat delirium is not recommended. | Kishi T | Evidence-based mental health | 2016 | ||
| Preoperative Cognitive Performance Dominates Risk for Delirium Among Older Adults. | Jones RN, Marcantonio ER, Saczynski JS, Tommet D, Gross AL, Travison TG, Alsop DC, Schmitt EM, Fong TG, Cizginer S, Shafi MM, Pascual-Leone A, Inouye SK | Journal of geriatric psychiatry and neurology | 2016 | ||
| Total intravenous anesthesia with propofol is associated with a lower rate of postoperative delirium in comparison with sevoflurane anesthesia in elderly patients. | Ishii K, Makita T, Yamashita H, Matsunaga S, Akiyama D, Toba K, Hara K, Sumikawa K, Hara T | Journal of clinical anesthesia | 2016 | ||
| Preclinical Amyloid-β and Axonal Degeneration Pathology in Delirium. | Idland AV, Wyller TB, Støen R, Eri LM, Frihagen F, Ræder J, Chaudhry FA, Hansson O, Zetterberg H, Blennow K, Bogdanovic N, Brækhus A, Watne LO | Journal of Alzheimer's disease : JAD | 2016 | ||
| The Mystery of Delirium. Could Biomarkers of Endothelial Activation Reveal the Secrets? | Frendl G | Critical care medicine | 2016 | ||
| A Simple Tool to Predict Development of Delirium After Elective Surgery. | Dworkin A, Lee DS, An AR, Goodlin SJ | Journal of the American Geriatrics Society | 2016 | ||
| Cardiovascular surgery nurses' level of knowledge regarding delirium. | Demir Korkmaz F, Gok F, Yavuz Karamanoglu A | Nursing in critical care | 2016 | ||
| Poster 30 Use of Delirium Triggering Medications Among Patients with Delirium at Admission to Inpatient Rehabilitation Facility. | Dabaghian L, Yonclas PP, Seidel B, Jasey NN, Oh-Park M | PM & R : the journal of injury, function, and rehabilitation | 2016 | ||
| Comparison of pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a protocol for a systematic review incorporating network meta-analyses. | Burry LD, Hutton B, Guenette M, Williamson D, Mehta S, Egerod I, Kanji S, Adhikari NK, Moher D, Martin CM, Rose L | Systematic reviews | 2016 | ||
| Unraveling the Relationship Between Delirium, Brain Damage, and Subsequent Cognitive Decline in a Cohort of Individuals Undergoing Surgery for Hip Fracture. | Beishuizen SJ, Scholtens RM, van Munster BC, de Rooij SE | Journal of the American Geriatrics Society | 2016 | ||
| Standardizing Management of Adults with Delirium Hospitalized on Medical-Surgical Units. | Angel C, Brooks K, Fourie J | The Permanente journal | 2016 | ||
| The utility of the clock drawing test in detection of delirium in elderly hospitalised patients. | Adamis D, Meagher D, O'Neill D, McCarthy G | Aging & mental health | 2016 | ||
| Effect of New Cerebral Ischemic Lesions on the Delirium Occurrence After Transcatheter Aortic Valve Replacement. | Abawi M, Nijhoff F, Agostoni P, de Vries R, Slooter AJ, Emmelot-Vonk MH, Voskuil M, Leiner T, Doevendans PA, Stella PR | Journal of the American College of Cardiology | 2016 | ||
| Is cobalamin deficiency associated with increased risk of all subtypes of postoperative delirium? | Wang LK, Lan KM, Lin YT, Chen JY | Neuropsychiatric disease and treatment | 2016 | ||
| Meeting the Challenges of Delirium Assessment Across the Aging Spectrum. | Smith HA, Han JH, Ely EW | Critical care medicine | 2016 | ||
| Response to Paul Regal. | Schmitt EM, Inouye SK | Journal of the American Geriatrics Society | 2016 | ||
| Is delirium the medical emergency we know least about? | Nagaraj G, Burkett E, Hullick C, Carpenter CR, Arendts G | Emergency medicine Australasia : EMA | 2016 | ||
| Earplugs might reduce intensive care unit delirium but quality of evidence is low. | Law AC, Walkey AJ | Evidence-based medicine | 2016 | ||
| The major risk factors for delirium in a clinical setting. | Kim H, Chung S, Joo YH, Lee JS | Neuropsychiatric disease and treatment | 2016 | ||
| Prevalence, determinants, and prognostic significance of delirium in patients with acute heart failure. | Honda S, Nagai T, Sugano Y, Okada A, Asaumi Y, Aiba T, Noguchi T, Kusano K, Ogawa H, Yasuda S, Anzai T, | International journal of cardiology | 2016 | ||
| Delirium in older adults: a chronic cognitive disorder? | Cole MG, Mccusker J | International psychogeriatrics / IPA | 2016 | ||
| Sedative choice and ventilator-associated patient outcomes: don't sleep on delirium. | Barnes SS, Kudchadkar SR | Annals of translational medicine | 2016 | ||
| The use of volunteers to help older medical patients mobilise in hospital: a systematic review. | Baczynska AM, Lim SE, Sayer AA, Roberts HC | Journal of clinical nursing | 2016 | ||
| The Geriatric Day Hospital: Preliminary Data on an Innovative Model of Care in Brazil for Older Adults at Risk of Hospitalization. | Aliberti MJ, Suemoto CK, Fortes-Filho SQ, Melo JA, Trindade CB, Kasai JY, Altona M, Apolinario D, Jacob-Filho W | Journal of the American Geriatrics Society | 2016 | ||
| Long-Term Mental Health Problems After Delirium in the ICU. | Wolters AE, Peelen LM, Welling MC, Kok L, de Lange DW, Cremer OL, van Dijk D, Slooter AJ, Veldhuijzen DS | Critical care medicine | 2016 | ||
| Delirium assessment in hospitalized elderly patients: Italian translation and validation of the nursing delirium screening scale. | Spedale V, Di Mauro S, Del Giorno G, Barilaro M, Villa CE, Gaudreau JD, Ausili D | Aging clinical and experimental research | 2016 | ||
| Insulin-like growth factor-1, a potential predicative biomarker for postoperative delirium among elderly patients with open abdominal surgery. | Shen H, Shao Y, Chen J, Guo J | Current pharmaceutical design | 2016 | ||
| Delirium the under-recognised syndrome: survey of healthcare professionals' awareness and practice in the intensive care units. | Selim AA, Wesley Ely E | Journal of clinical nursing | 2017 |
Adult, Attitude of Health Personnel, Critical Care, organization & administration, Cross-Sectional Studies, Delirium, diagnosis, Disease Management, Egypt, Female, Health Care Surveys, Health Knowledge, Attitudes, Practice, Health Personnel, psychology, Humans, Intensive Care Units, organization & administration, Male, Middle Aged, Nursing Staff, Hospital, psychology, Physicians, psychology, Surveys and Questionnaires |
|
| Intra-operative events during cardiac surgery are risk factors for the development of delirium in the ICU. | Rudiger A, Begdeda H, Babic D, Krüger B, Seifert B, Schubert M, Spahn DR, Bettex D | Critical care (London, England) | 2016 | ||
| Validity and Reliability of the 6-Item Cognitive Impairment Test for Screening Cognitive Impairment: A Review. | O'Sullivan D, O'Regan NA, Timmons S | Dementia and geriatric cognitive disorders | 2016 | ||
| Delirium in elderly patients: association with educational attainment. | Martins S, Paiva JA, Simões MR, Fernandes L | Acta neuropsychiatrica | 2017 |
Aged, Aged, 80 and over, Cognitive Reserve, Delirium, epidemiology, Educational Status, Female, Glasgow Coma Scale, Humans, Male, Portugal, epidemiology, Psychiatric Status Rating Scales |
|
| Prevalence of Delirium in Older Medical Inpatients in Tanzania. | Lewis E, Paddick SM, Banks J, Duinmaijer A, Tucker L, Kisoli A, Cletus J, Lissu C, Dotchin C, Gray W, Walker R, Urasa S | Journal of the American Geriatrics Society | 2016 | ||
| Preventing postoperative delirium: all that glisters is not gold. | Kronzer VL, Avidan MS | Lancet (London, England) | 2016 | ||
| Trajectory of Functional Recovery After Postoperative Delirium in Elective Surgery. | Hshieh TT, Saczynski J, Gou RY, Marcantonio E, Jones RN, Schmitt E, Cooper Z, Ayres D, Wright J, Travison TG, Inouye SK, | Annals of surgery | 2017 | ||
| Evaluation of delirium screening tools in geriatric medical inpatients: a diagnostic test accuracy study. | Hendry K, Quinn TJ, Evans J, Scortichini V, Miller H, Burns J, Cunnington A, Stott DJ | Age and ageing | 2016 | ||
| Mind Over Matter? The Hidden Epidemic of Cognitive Dysfunction in the Older Surgical Patient. | O' Brien H, Mohan H, Hare CO, Reynolds JV, Kenny RA | Annals of surgery | 2016 | ||
| The Impact of Interventions to Improve Sleep on Delirium in the ICU: A Systematic Review and Research Framework. | Flannery AH, Oyler DR, Weinhouse GL | Critical care medicine | 2016 | ||
| Neuroinflammatory challenges compromise neuronal function in the aging brain: Postoperative cognitive delirium and Alzheimer's disease. | Cortese GP, Burger C | Behavioural brain research | 2016 | ||
| Delirium: Time to climb this babylon tower. | Capponi MG, Biffi AM, Spada MS, Ansaloni L | European journal of internal medicine | 2017 | ||
| Preventing delirium: beyond dexmedetomidine. | Avramescu S, Wang DS, Choi S, Orser BA | Lancet (London, England) | 2017 | ||
| Prevalence and Risk Factors for Delirium in Acute Stroke Patients. A Retrospective 5-Years Clinical Series. | Alvarez-Perez FJ, Paiva F | Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association | 2017 | ||
| An evolving approach to delirium: A mixed-methods process evaluation of a hospital-wide delirium program in New Zealand. | Alhaidari AA, Allen-Narker RA | Australasian journal on ageing | 2017 | ||
| Delirium superimposed on dementia: phenomenological differences between patients with and without behavioral and psychological symptoms of dementia in a specialized delirium unit. | Abengaña J, Chong MS, Tay L | International psychogeriatrics | 2017 | ||
| Incidence, risk factors and outcomes of delirium in intensive care unit of universiti kebangsaan malaysia medical centre | Vyveganathan, L., Izaham, A., Mohamad Yusof, A., Wan Mat, W. R., Abdul Rahman, R., Abdul Manap, N. | Anesthesia and Analgesia | 2016 |
bilirubin |
|
| Influence of acute delirium on short-term prognosis in elderly acute decompensated heart failure patients | Tagahara, K., Azioka, M., Nakashima, Y., Osanai, H., Inoue, Y., Kanbara, T., Yoshida, T., Masutomi, T., Ohashi, H., Tobe, A. | Journal of Cardiac Failure | 2016 |
acute heart failure |
|
| Implementing a delirium prevention programme can reduce falls in hospital geriatric medicine wards | Solomonsz, A., Charalambous, L., Taylor, R., Blackshaw, E., Ali, A., Morris, R., Moorchilot, R., Poon, M., Blundell, A., Harwood, R., Masud, T. | European Geriatric Medicine | 2016 | ||
| Emergence delirium in adult patients after general anaesthesia-a prospective study from the caribbean | Ramroop, R., Hariharan, S., Chen, D. | Anesthesia and Analgesia | 2016 |
atropine |
|
| Optimized anesthesia to reduce incidence of postoperative delirium in elderly undergoing elective, non-cardiac surgery: A randomized controlled trial | Punjasawadwong, Y., Pipanmekaporn, T., Wongpakaran, N. | Anesthesia and Analgesia | 2016 |
aged |
|
| Evaluation of the idea (identification and interventions for dementia in elderly Africans) brief cognitive screening tool for identification of delirium in older hospitalised adults in Tanzania | Paddick, S. M., Lewis, E. G., Duinmaijer, A. T., Banks, J., Urasa, S., Tucker, L., Kisoli, A., Cletus, J., Lissu, C., Kisima, J., Dotchin, C., Gray, W. K., Mushi, D., Walker, R. | Alzheimer's and Dementia | 2016 |
adult |
|
| Effectiveness of Educational Enhancement for Clinicians Regarding Understanding and Applying Confusion Assessment Method in the ICU (CAM-ICU) | Pandya, T., Hanna, M., Ghazarian, Z., Sekhon, R., Ismail, M. | CHEST | 2016 | ||
| Improving the detection of delirium, depression and suspected dementia in community hospital settings | North, C., Russell, G., Hayes, N. | European Geriatric Medicine | 2016 |
community hospital |
|
| 127 Emergency Department Interventions and Their Effect on Delirium's Natural Course: The Folly May Be in the Foley | Noel, C., Cirbus, J., Han, J.H. | Annals of Emergency Medicine | 2016 |
Delirium Geriatrics Psychiatry |
|
| Identifying and managing delirium on admission | Musaddaq, B., Bakshi, P., Roseman, H., Pleming, J., Saber, S., Wu, A., Mizoguchi, R. | European Geriatric Medicine | 2016 |
aged |
|
| Association between mini nutritional assessment (MNA) and the development of delirium in elderly patients with hip fracture | Lozano-Montoya, I., Miret-Corchado, C., Vaquero-Pinto, M. N., Roldán-Plaza, C., Sánchez-García, E., Cruz-Jentoft, A. | European Geriatric Medicine | 2016 |
aged |
|
| Comparison between cerebrolysin and citicoline in the incidence of postoperative delirium in adult cardiac surgical patients | Lespron, M. D. C., Morales, O., Molina, F. J., Figueroa, J., Suárez, L., Molina, A., Guerrero, R., Alvarez, H., Telona, E. J. | Anesthesia and Analgesia | 2016 |
cerebrolysin |
|
| A comparison between confusion assessment method in intensive care unit (CAM-ICU) and neelon-champagne (NEECHAM) confusion scale | Karci, O., Serin, S., Sungurtekin, H. | 2016 |
adult |
||
| Promoting Sleep to Improve Delirium in the ICU∗ | Kamdar, B. B., Martin, J. L., Needham, D. M., Ong, M. K. | Critical Care Medicine | 2016 |
critical illness |
|
| Delirium as a non-traumatic brain injury: Older patients with delirium have similar biomarker profiles to patients with isolated traumatic brain injury | Jackson, T. A., Shears, B., Lord, J. M., Belli, A., Hazeldine, J. | European Geriatric Medicine | 2016 |
biological marker |
|
| Comprehensive geriatric assessment for prevention of delirium post hip fracture: A systematic review of randomised controlled trials | Henderson, V., Shields, L., Clasake, R. | European Geriatric Medicine | 2016 |
|
|
| Long-term prognostic value of DELIRIUM in elderly patients with acute Cardiac diseases admitted to two cardiac intensive care unit: A prospective study | Grotti, S., Falsini, G., Porto, I., Toccafondi, G., Fraticelli, A., Angioli, P., Ducci, K., Liistro, F., Pieroni, M., Taddei, T., Romanelli, S., Rossie, R., Bolognese, L. | European Heart Journal: Acute Cardiovascular Care | 2016 |
|
|
| Hospitalised older people with dementia and delirium: More readmissions and in-hospital complications, greater length of stay and associated healthcare costs | Giudice, D. L., Tropea, J., Brand, C.A., Gorelik, A. Liew, D. | Alzheimer's and Dementia | 2016 |
Australia |
|
| Progressive brain atrophy and cognitive decline along with multiple episodes of delirium. | Hayakawa K, Kato TA, Imamura S, Kasai N, Kanba S | Psychiatry and clinical neurosciences | 2017 | ||
| Case of insulinoma manifesting as hyperinsulinemia after discontinuing quetiapine in an elderly patient with delirium. | Yamamoto N, Oh E, Nishiyama K, Yoshida M, Saeki A, Ishii H, Takeda Y, Hamahata T, Sugino M | Geriatrics & gerontology international | 2017 | ||
| A National Multicenter Survey on Management of Pain, Agitation, and Delirium in Intensive Care Units in China. | Wang J, Peng ZY, Zhou WH, Hu B, Rao X, Li JG | Chinese medical journal | 2017 | ||
| High C-Reactive Protein Predicts Delirium Incidence, Duration, and Feature Severity After Major Noncardiac Surgery. | Vasunilashorn SM, Dillon ST, Inouye SK, Ngo LH, Fong TG, Jones RN, Travison TG, Schmitt EM, Alsop DC, Freedman SD, Arnold SE, Metzger ED, Libermann TA, Marcantonio ER | Journal of the American Geriatrics Society | 2017 | ||
| Interventions to Reduce Postoperative Delirium: Aligning Surgical Care With Patients' Needs and Priorities. | Suwanabol PA, Hinshaw DB | JAMA surgery | 2017 | ||
| Assessment of Delirium in Intensive Care Unit Patients: Educational Strategies. | Smith JM, Van Aman MN, Schneiderhahn ME, Edelman R, Ercole PM | Journal of continuing education in nursing | 2017 | ||
| Pathophysiological and behavioral effects of systemic inflammation in aged and diseased rodents with relevance to delirium: A systematic review. | Schreuder L, Eggen BJ, Biber K, Schoemaker RG, Laman JD, de Rooij SE | Brain, behavior, and immunity | 2017 | ||
| Effectiveness of haloperidol prophylaxis in critically ill patients with a high risk of delirium: a systematic review. | Santos E, Cardoso D, Neves H, Cunha M, Rodrigues M, Apóstolo J | JBI database of systematic reviews and implementation reports | 2017 |