What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
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Reference Information
- Title
- Delirium is associated with frequency band specific dysconnectivity in intrinsic connectivity networks: preliminary evidence from a large retrospective pilot case-control study.
- Authors
- Fleischmann, R. Traenkner, S. Kraft, A. Schmidt, S. Schreiber, S. J. Brandt, S. A.
- Year
- 2019
- Journal
- Pilot Feasibility Stud
- Abstract
Background: Pathophysiological concepts in delirium are not sufficient to define objective biomarkers suited to improve clinical approaches. Advances in neuroimaging have revalued electroencephalography (EEG) as a tool to assess oscillatory network activity in neuropsychiatric disease. Yet, research in the field is limited to small populations and largely confined to postoperative delirium, which impedes generalizability of findings and planning of prospective studies in other populations. This study aimed to assess effect sizes of connectivity measures in a large mixed population to demonstrate that there are measurable EEG differences between delirium and control patients. Methods: This retrospective pilot study investigated EEG measures as biomarkers in delirium using a case-control design including patients diagnosed with delirium (DSM-5 criteria) and age-/gender-matched controls drawn from a database of 9980 patients (n = 129 and 414, respectively). Assessors were not blinded for groups. Power spectra and connectivity estimates, using the weighted phase log index, of continuous EEG data were compared between conditions. Alterations of information flow through nodes of intrinsic connectivity networks (ICN; default mode, salience, and executive control network) were evaluated in source space using betweenness centrality. This was done frequency specific and network nodes were defined by the multimodal human cerebral cortex parcellation based on human connectome project data. Results: Delirium and control patients exhibited distinct EEG power, connectivity, and network characteristics (F (72,540) = 70.3, p < .001; F (493,1079) = 2.69, p < .001; and F (718,2159) = 1.14, p = .007, respectively). Connectivity analyses revealed global alpha and regional beta band disconnectivity that was accompanied by theta band hyperconnectivity in delirious patients. Source and network analyses yielded that these changes are not specific to single intrinsic connectivity networks but affect multiple nodes of networks engaged in level of consciousness, attention, working memory, executive control, and salience detection. Effect sizes were medium to strong in this mixed population of delirious patients. Conclusions: We quantified effect sizes for EEG connectivity and network analyses to be expected in delirium. This study implicates that theta band hyperconnectivity and alpha band disconnectivity may be essential mechanisms in the pathophysiology of delirium. Upcoming prospective studies will build upon these results and evaluate the clinical utility of identified EEG measures as therapeutic and prognostic biomarkers.
- PMID
- Keywords
Biomarker
Delirium
Oscillatory activity
Source analysis
electroencephalography
accordance with the ethical standards of the institutional research committee and
with the 1964 Helsinki declaration and its later amendments or comparable ethical
standards. As a retrospective study in Germany, a separate approval is waived.Not
applicable.The authors declare that they have no competing interests.Springer
Nature remains neutral with regard to jurisdictional claims in published maps and
institutional affiliations.
- Page(s)
- Volume
- 5
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Delirium educational interventions should address negative attitudes and focus on promoting learning through practice. | Teodorczuk A, Mukaetova-Ladinska E | Journal of the American Geriatrics Society | 2014 |
Delirium, diagnosis, Health Personnel, education, Humans |
| EEG patterns compatible with nonconvulsive status epilepticus are common in elderly patients with delirium: a prospective study with continuous EEG monitoring. | Gilles N, Chantal D, Claire M, Keziah K, Thierry P, Benjamin L | Epilepsy & behavior : E&B | 2014 | |
| Duration of delirium and patient-centered outcomes: embracing the short- and long-term perspective. | Anderson BJ, Mikkelsen ME | Critical care medicine | 2014 |
Delirium |
| Clarifying the confusion surrounding drug-associated delirium in the ICU. | Devlin JW, Zaal IJ, Slooter AJ | Critical care medicine | 2014 |
Acute Lung Injury, drug therapy, Adrenal Cortex Hormones, adverse effects, Delirium, etiology, Female, Humans, Male, Respiration, Artificial |
| Incidence and risk factors of delirium in the elderly general surgical patient. | de Castro SM, Ünlü Ç, Tuynman JB, Honig A, van Wagensveld BA, Steller EP, Vrouenraets BC | American journal of surgery | 2014 |
Age Factors, Aged, Aged, 80 and over, Delirium, diagnosis, Female, General Surgery, Hospitalization, Humans, Incidence, Length of Stay, Logistic Models, Male, Middle Aged, Multivariate Analysis, Preoperative Period, Prospective Studies, Psychiatric Status Rating Scales, Risk Factors, Surgical Procedures, Elective, Surgical Procedures, Operative |
| Delirium and the Family Caregiver: The Need for Evidence-based Education Interventions. | Carbone MK, Gugliucci MR | The Gerontologist | 2015 |
Adaptation, Psychological, Adult, Aged, Caregivers, Delirium, nursing, Family, Humans, Quality of Life, Social Support |
| Newly identified precipitating factors in mechanical ventilation-induced brain damage: implications for treating ICU delirium. | González-López A, Albaiceta GM, Talbot K | Expert review of neurotherapeutics | 2014 | |
| Gender differences in factors associated with delirium severity in older adults with dementia. | Kolanowski AM, Hill NL, Kurum E, Fick DM, Yevchak AM, Mulhall P, Clare L, Valenzuela M | Archives of psychiatric nursing | 2014 | |
| Length of red cell unit storage and risk for delirium after cardiac surgery. | Brown CH, Grega M, Selnes OA, McKhann GM, Shah AS, LaFlam A, Savage WJ, Frank SM, Hogue CW, Gottesman RF | Anesthesia and analgesia | 2014 |
Aged, Aged, 80 and over, Baltimore, Blood Banks, Blood Preservation, adverse effects, Cardiac Surgical Procedures, adverse effects, Cardiopulmonary Bypass, adverse effects, Case-Control Studies, Chi-Square Distribution, Coronary Artery Bypass, adverse effects, Delirium, diagnosis, Erythrocyte Transfusion, adverse effects, Female, Heart Valve Prosthesis Implantation, adverse effects, Humans, Logistic Models, Male, Middle Aged, Multivariate Analysis, Odds Ratio, Postoperative Hemorrhage, etiology, Prospective Studies, Risk Factors, Time Factors, Treatment Outcome, Vascular Surgical Procedures, adverse effects |
| Delirium and dementia with Lewy bodies: distinct diagnoses or part of the same spectrum? | Gore RL, Vardy ER, O'Brien JT | Journal of neurology, neurosurgery, and psychiatry | 2015 |
Accidental Falls, Affective Symptoms, complications, Biological Markers, blood, Brain, metabolism, Cognition Disorders, complications, Consciousness Disorders, complications, Delirium, blood, Delusions, complications, Functional Neuroimaging, Humans, Lewy Body Disease, blood, Movement Disorders, complications, Perceptual Disorders, complications, Sleep Disorders, complications, Syncope, complications |
| Preoperative assessment of the older patient: a narrative review. | Oresanya LB, Lyons WL, Finlayson E | JAMA | 2014 |
Aged, Aged, 80 and over, Decision Making, Frail Elderly, Geriatric Assessment, Humans, Informed Consent, Odds Ratio, Preoperative Period, Risk Assessment, Surgical Procedures, Operative, adverse effects |
| Postoperative delirium and pre-fracture disability predict 6-month mortality among the oldest old hip fracture patients. | Mazzola P, Bellelli G, Broggini V, Anzuini A, Corsi M, Berruti D, De Filippi F, Zatti G, Annoni G | Aging clinical and experimental research | 2015 | |
| Can an e-learning course improve nursing care for older people at risk of delirium: a stepped wedge cluster randomised trial. | van de Steeg L, IJkema R, Langelaan M, Wagner C | BMC geriatrics | 2014 |
Aged, Aged, 80 and over, Delirium, diagnosis, Education, Distance, methods, Female, Humans, Male, Netherlands, epidemiology, Nursing Care, standards, Nursing Staff, education, Quality Improvement, standards, Risk Factors |
| Delirium and high Fever are associated with subacute motor deterioration in Parkinson disease: a nested case-control study. | Umemura A, Oeda T, Tomita S, Hayashi R, Kohsaka M, Park K, Sugiyama H, Sawada H | PloS one | 2014 | |
| Inflammation biomarkers and delirium in critically ill patients. | Ritter C, Tomasi CD, Dal-Pizzol F, Pinto BB, Dyson A, de Miranda AS, Comim CM, Soares M, Teixeira AL, Quevedo J, Singer M | Critical care (London, England) | 2014 | |
| Geriatric Assessment as a Predictor of Delirium and Other Outcomes in Elderly Patients With Cancer. | Korc-Grodzicki B, Sun SW, Zhou Q, Iasonos A, Lu B, Root JC, Downey RJ, Tew WP | Annals of surgery | 2014 | |
| Duration of postoperative delirium is an independent predictor of 6-month mortality in older adults after hip fracture. | Bellelli G, Mazzola P, Morandi A, Bruni A, Carnevali L, Corsi M, Zatti G, Zambon A, Corrao G, Olofsson B, Gustafson Y, Annoni G | Journal of the American Geriatrics Society | 2014 |
Aged, 80 and over, Delirium, epidemiology, Female, Hip Fractures, mortality, Humans, Male, Postoperative Complications, epidemiology, Prognosis, Prospective Studies, Time Factors |
| Delirium in advanced cancer: screening for the incidence on admission to an inpatient hospice unit. | Rainsford S, Rosenberg JP, Bullen T | Journal of palliative medicine | 2014 | |
| Long-term outcome of delirium during intensive care unit stay in survivors of critical illness: a prospective cohort study. | Wolters AE, van Dijk D, Pasma W, Cremer OL, Looije MF, de Lange DW, Veldhuijzen DS, Slooter AJ | Critical care (London, England) | 2014 | |
| Impact of delirium and suture-less securement on accidental vascular catheter removal in the ICU. | Sundararajan K, Wills S, Chacko B, Kanabar G, O'Connor S, Deane AM | Anaesthesia and intensive care | 2014 |
Adolescent, Adult, Aged, Aged, 80 and over, Australia, epidemiology, Catheterization, Central Venous, instrumentation, Catheters, statistics & numerical data, Causality, Child, Child, Preschool, Delirium, epidemiology, Female, Humans, Incidence, Infant, Intensive Care, methods, Intensive Care Units, statistics & numerical data, Male, Middle Aged, Odds Ratio, Postoperative Complications, epidemiology, Prospective Studies, Risk Factors, Suture Techniques, instrumentation, Young Adult |
| Delirium, subsyndromal delirium, and cognitive changes in individuals undergoing elective coronary artery bypass graft surgery. | Li HC, Chen YS, Chiu MJ, Fu MC, Huang GH, Chen CC | The Journal of cardiovascular nursing | 2015 | |
| Delirium during Weaning from Mechanical Ventilation. | Leite MA, Osaku EF, Costa CR, Cândia MF, Toccolini B, Covatti C, Costa NL, Nogueira ST, Ogasawara SM, de Albuquerque CE, Pilatti CM, Piana PA, Jorge AC, Duarte PA | Critical care research and practice | 2014 | |
| INCOG recommendations for management of cognition following traumatic brain injury, part I: posttraumatic amnesia/delirium. | Ponsford J, Janzen S, McIntyre A, Bayley M, Velikonja D, Tate R, | The Journal of head trauma rehabilitation | 2014 | |
| Delirium Screening in Cardiac Surgery (DESCARD): a useful tool for nonpsychiatrists. | Krzych LJ, Wybraniec MT, Krupka-Matuszczyk I, Skrzypek M, Bochenek AA | The Canadian journal of cardiology | 2014 |
Age Factors, Aged, Algorithms, Blood Glucose, analysis, Body Weight, Brain Ischemia, epidemiology, Cardiovascular Surgical Procedures, Cohort Studies, Delirium, diagnosis, Diabetes Mellitus, epidemiology, Diagnostic and Statistical Manual of Mental Disorders, Erythrocyte Transfusion, Fasting, blood, Female, Humans, Hypertension, epidemiology, Male, Middle Aged, Postoperative Complications, diagnosis, Postoperative Period, Predictive Value of Tests, Preoperative Period, Proteins, analysis, ROC Curve, Risk Assessment, methods, Risk Factors, Sensitivity and Specificity |
| Pilot study on the European Portuguese version of the Confusion Assessment Method. | Martins S, Moldes P, Pinto-de-Sousa J, Conceição F, Paiva JA, Simões MR, Fernandes L | Acta neuropsychiatrica | 2014 | |
| Evaluation of preoperative geriatric assessment of elderly patients with colorectal carcinoma. A retrospective study. | Indrakusuma R, Dunker MS, Peetoom JJ, Schreurs WH | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology | 2015 | |
| C-reactive Protein Predicts Postoperative Delirium Following Vascular Surgery. | Pol RA, van Leeuwen BL, Izaks GJ, Reijnen MM, Visser L, Tielliu IF, Zeebregts CJ | Annals of vascular surgery | 2014 | |
| Untangling ICU delirium: is establishing its prevention in high-risk patients the final frontier? | van der Jagt M, Trogrlic Z, Ista E | Intensive care medicine | 2014 | |
| Post-operative delirium in elderly patients. | Vijayakumar B, Elango P, Ganessan R | Indian journal of anaesthesia | 2014 | |
| What are the factors associated with physical activity (PA) participation in community dwelling adults with dementia? A systematic review of PA correlates. | Stubbs B, Eggermont L, Soundy A, Probst M, Vandenbulcke M, Vancampfort D | Archives of gerontology and geriatrics | 2014 | |
| Dexmedetomidine reduces the risk of delirium, agitation and confusion in critically Ill patients: a meta-analysis of randomized controlled trials. | Pasin L, Landoni G, Nardelli P, Belletti A, Di Prima AL, Taddeo D, Isella F, Zangrillo A | Journal of cardiothoracic and vascular anesthesia | 2014 | |
| Incidence of delirium following total joint replacement in older adults: a meta-analysis. | Scott JE, Mathias JL, Kneebone AC | General hospital psychiatry | 2015 | |
| Severity of delirium in the ICU is associated with short term cognitive impairment. A prospective cohort study. | Sakuramoto H, Subrina J, Unoki T, Mizutani T, Komatsu H | Intensive & critical care nursing : the official journal of the British Association of Critical Care Nurses | 2015 | |
| Impact of malnutrition on postoperative delirium development after on pump coronary artery bypass grafting. | Ringaitienė D, Gineitytė D, Vicka V, Žvirblis T, Šipylaitė J, Irnius A, Ivaškevičius J, Kačergius T | Journal of cardiothoracic surgery | 2015 | |
| Association of cumulative dose of haloperidol with next-day delirium in older medical ICU patients. | Pisani MA, Araujo KL, Murphy TE | Critical care medicine | 2015 |
APACHE, Age Factors, Aged, Aged, 80 and over, Cognition Disorders, complications, Delirium, chemically induced, Dose-Response Relationship, Drug, Female, Haloperidol, administration & dosage, Humans, Intensive Care Units, statistics & numerical data, Male, Middle Aged, Prospective Studies, Risk Factors, Sex Factors, Time Factors |
| The confusion assessment method for the intensive care unit in patients with cirrhosis. | Orman ES, Perkins A, Ghabril M, Khan BA, Chalasani N, Boustani MA | Metabolic brain disease | 2015 | |
| In geriatric patients, delirium symptoms are related to the anticholinergic burden. | Naja M, Zmudka J, Hannat S, Liabeuf S, Serot JM, Jouanny P | Geriatrics & gerontology international | 2015 | |
| The impact of lymphopenia on delirium in ICU patients. | Inoue S, Vasilevskis EE, Pandharipande PP, Girard TD, Graves AJ, Thompson J, Shintani A, Ely EW | PloS one | 2015 | |
| Neuropsychological profiles of an elderly cohort undergoing elective surgery and the relationship between cognitive performance and delirium. | Fong TG, Hshieh TT, Wong B, Tommet D, Jones RN, Schmitt EM, Puelle MR, Saczynski JS, Marcantonio ER, Inouye SK | Journal of the American Geriatrics Society | 2015 | |
| Influence of intraoperative cerebral oximetry monitoring on neurocognitive function after coronary artery bypass surgery: a randomized, prospective study. | Colak Z, Borojevic M, Bogovic A, Ivancan V, Biocina B, Majeric-Kogler V | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery | 2015 | |
| Pre-surgical Geriatric Syndromes, Frailty, and Risks for Postoperative Delirium in Older Patients Undergoing Gastrointestinal Surgery: Prevalence and Red Flags. | Chen CC, Lin MT, Liang JT, Chen CM, Yen CJ, Huang GH | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract | 2015 | |
| Subsyndromal delirium after cardiac surgery. | Breu A, Stransky M, Metterlein T, Werner T, Trabold B | Scandinavian cardiovascular journal : SCJ | 2015 | |
| Stability of postoperative delirium psychomotor subtypes in individuals with hip fracture. | Albrecht JS, Marcantonio ER, Roffey DM, Orwig D, Magaziner J, Terrin M, Carson JL, Barr E, Brown JP, Gentry EG, Gruber-Baldini AL, | Journal of the American Geriatrics Society | 2015 | |
| Relationship between neurological complications, cerebrovascular and cerebral perfusion following off-pump coronary artery bypass grafting. | Xu B, Qiao Q, Chen M, Rastogi R, Luo D, Bi Q | Neurological research | 2015 | |
| Delayed sequence intubation: a prospective observational study. | Weingart SD, Trueger NS, Wong N, Scofi J, Singh N, Rudolph SS | Annals of emergency medicine | 2015 | |
| Multinational development and validation of an early prediction model for delirium in ICU patients. | Wassenaar A, van den Boogaard M, van Achterberg T, Slooter AJ, Kuiper MA, Hoogendoorn ME, Simons KS, Maseda E, Pinto N, Jones C, Luetz A, Schandl A, Verbrugghe W, Aitken LM, van Haren FM, Donders AR, Schoonhoven L, Pickkers P | Intensive care medicine | 2015 | |
| Association between intraoperative blood pressure and postoperative delirium in elderly hip fracture patients. | Wang NY, Hirao A, Sieber F | PloS one | 2015 | |
| Recognizing acute delirium as part of your routine [RADAR]: a validation study. | Voyer P, Champoux N, Desrosiers J, Landreville P, McCusker J, Monette J, Savoie M, Richard S, Carmichael PH | BMC nursing | 2015 | |
| A systematic review of implementation strategies for assessment, prevention, and management of ICU delirium and their effect on clinical outcomes. | Trogrlić Z, van der Jagt M, Bakker J, Balas MC, Ely EW, van der Voort PH, Ista E | Critical care (London, England) | 2015 |
Clinical Trials as Topic, methods, Critical Care, methods, Delirium, diagnosis, Disease Management, Humans, Intensive Care Units, Treatment Outcome |
| Intraoperative burst suppression is associated with postoperative delirium following cardiac surgery: a prospective, observational study. | Soehle M, Dittmann A, Ellerkmann RK, Baumgarten G, Putensen C, Guenther U | BMC anesthesiology | 2015 | |
| Clinical effectiveness of a sedation protocol minimizing benzodiazepine infusions and favoring early dexmedetomidine: a before-after study. | Skrupky LP, Drewry AM, Wessman B, Field RR, Fagley RE, Varghese L, Lieu A, Olatunde J, Micek ST, Kollef MH, Boyle WA | Critical care (London, England) | 2015 | |
| Pharmacologic prevention and treatment of delirium in intensive care patients: A systematic review. | Serafim RB, Bozza FA, Soares M, do Brasil PE, Tura BR, Ely EW, Salluh JI | Journal of critical care | 2015 | |
| Postoperative delirium in elderly after elective and acute colorectal surgery: A Prospective Cohort Study. | Raats JW, Steunenberg SL, Crolla RM, Wijsman JH, Slaa AT, van der Laan L | International journal of surgery (London, England) | 2015 | |
| Validation study of the European Portuguese version of the Confusion Assessment Method (CAM). | Martins S, Lourenço C, Pinto-de-Sousa J, Conceição F, Paiva JA, Simões MR, Fernandes L | International psychogeriatrics / IPA | 2015 | |
| Neurocognitive dysfunction risk alleviation with the use of dexmedetomidine in perioperative conditions or as ICU sedation: a meta-analysis. | Li B, Wang H, Wu H, Gao C | Medicine | 2015 | |
| Incidence and Risk Factors for Delirium among Mechanically Ventilated Patients in an African Intensive Care Setting: An Observational Multicenter Study. | Kwizera A, Nakibuuka J, Ssemogerere L, Sendikadiwa C, Obua D, Kizito S, Tumukunde J, Wabule A, Nakasujja N | Critical care research and practice | 2015 | |
| Implications of atypical antipsychotic prescribing in the intensive care unit. | Kram BL, Kram SJ, Brooks KR | Journal of critical care | 2015 | |
| The Mortality Risk of Conventional Antipsychotics in Elderly Patients: A Systematic Review and Meta-analysis of Randomized Placebo-Controlled Trials. | Hulshof TA, Zuidema SU, Ostelo RW, Luijendijk HJ | Journal of the American Medical Directors Association | 2015 | |
| Acute symptomatic complications among patients with advanced cancer admitted to acute palliative care units: A prospective observational study. | Hui D, Dos Santos R, Reddy S, Nascimento MS, Zhukovsky DS, Paiva CE, Dalal S, Costa ED, Walker P, Scapulatempo HH, Dev R, Crovador CS, De La Cruz M, Bruera E | Palliative medicine | 2015 | |
| Characteristics of older adults admitted to the emergency department (ED) and their risk factors for ED readmission based on comprehensive geriatric assessment: a prospective cohort study. | Deschodt M, Devriendt E, Sabbe M, Knockaert D, Deboutte P, Boonen S, Flamaing J, Milisen K | BMC geriatrics | 2015 |
Activities of Daily Living, Age Factors, Aged, Aged, 80 and over, Belgium, Comorbidity, Delirium, complications, Emergency Service, Hospital, Female, Geriatric Assessment, Hospitals, University, Humans, Male, Nutritional Status, Patient Discharge, Patient Readmission, Prospective Studies, Risk Factors, Time Factors |
| Hospital Elder Life Program in the real world: the many uses of the Hospital Elder Life Program website. | Chen P, Dowal S, Schmitt E, Habtemariam D, Hshieh TT, Victor R, Boockvar KS, Inouye SK | Journal of the American Geriatrics Society | 2015 | |
| Brain atrophy and white-matter hyperintensities are not significantly associated with incidence and severity of postoperative delirium in older persons without dementia. | Cavallari M, Hshieh TT, Guttmann CR, Ngo LH, Meier DS, Schmitt EM, Marcantonio ER, Jones RN, Kosar CM, Fong TG, Press D, Inouye SK, Alsop DC, | Neurobiology of aging | 2015 | |
| Psychometric Properties of the Family Caregiver Delirium Knowledge Questionnaire. | Bull MJ, Avery JS, Boaz L, Oswald D | Research in gerontological nursing | 2015 |
Adult, Aged, Aged, 80 and over, Caregivers, education, Cross-Sectional Studies, Delirium, diagnosis, Female, Health Knowledge, Attitudes, Practice, Home Nursing, education, Humans, Male, Middle Aged, Psychometrics, instrumentation, Questionnaires, Reproducibility of Results, Wisconsin, Young Adult |
| Delirium and other clinical factors with Clostridium difficile infection that predict mortality in hospitalized patients. | Archbald-Pannone LR, McMurry TL, Guerrant RL, Warren CA | American journal of infection control | 2015 | |
| What does delirium cost? : An economic evaluation of hyperactive delirium. | Weinrebe W, Johannsdottir E, Karaman M, Füsgen I | Zeitschrift fur Gerontologie und Geriatrie | 2016 | |
| Predicting postoperative delirium after vascular surgical procedures. | Visser L, Prent A, van der Laan MJ, van Leeuwen BL, Izaks GJ, Zeebregts CJ, Pol RA | Journal of vascular surgery | 2015 |
Aged, Aged, 80 and over, Amputation, adverse effects, Aorta, surgery, Chi-Square Distribution, Cognition Disorders, complications, Databases, Factual, Delirium, diagnosis, Elective Surgical Procedures, Female, Humans, Incidence, Logistic Models, Male, Middle Aged, Multivariate Analysis, Netherlands, Odds Ratio, Prospective Studies, Risk Assessment, Risk Factors, Treatment Outcome, Vascular Surgical Procedures, adverse effects |
| Development of a smartphone application for the objective detection of attentional deficits in delirium. | Tieges Z, Stíobhairt A, Scott K, Suchorab K, Weir A, Parks S, Shenkin S, MacLullich A | International psychogeriatrics / IPA | 2015 | |
| Association of point prevalence diagnosis of delirium on length of stay, 6-month mortality, and level of care on discharge at Waitemata District Health Board, Auckland. | Tan AH, Scott J | The New Zealand medical journal | 2015 |
Aged, Aged, 80 and over, Delirium, epidemiology, Humans, Institutionalization, statistics & numerical data, Length of Stay, Medical Audit, New Zealand, Patient Discharge, Prevalence |
| The prevalence, risk factors and short-term outcomes of delirium in Thai elderly emergency department patients. | Sri-On J, Tirrell GP, Vanichkulbodee A, Niruntarai S, Liu SW | Emergency medicine journal : EMJ | 2016 | |
| The impact of a delirium educational intervention with intensive care unit nurses. | Speed G | Clinical nurse specialist CNS | 2015 | |
| Preoperative cognitive intervention reduces cognitive dysfunction in elderly patients after gastrointestinal surgery: a randomized controlled trial. | Saleh AJ, Tang GX, Hadi SM, Yan L, Chen MH, Duan KM, Tong J, Ouyang W | Medical science monitor : international medical journal of experimental and clinical research | 2015 | |
| Current factors of fragility and delirium in vascular surgery. | Raats JW, van Hoof-de Lepper CC, Feitsma MT, Meij JJ, Ho GH, Mulder PG, van der Laan L | Annals of vascular surgery | 2015 | |
| Pharmacist calls to older adults with cognitive difficulties after discharge in a tertiary veterans administration medical center: a quality improvement program. | Paquin AM, Salow M, Rudolph JL | Journal of the American Geriatrics Society | 2015 | |
| Alcoholic and postoperative delirium: a case-control study. | Novaković M, Dejanović SĐ, Marić-Burmazević J, Dakić Z, Dimitrijević I | Psychiatria Danubina | 2015 | |
| Outcomes associated with postoperative delirium after cardiac surgery. | Mangusan RF, Hooper V, Denslow SA, Travis L | American journal of critical care : an official publication, American Association of Critical-Care Nurses | 2015 | |
| Hospitalisation and comorbidities in Parkinson's disease: a large Australian retrospective study. | Lubomski M, Rushworth RL, Tisch S | Journal of neurology, neurosurgery, and psychiatry | 2015 | |
| Delirium in fast-track colonic surgery. | Kurbegovic S, Andersen J, Krenk L, Kehlet H | Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie | 2015 | |
| Reliability and Validity of the Intensive Care Delirium Screening Checklist in Turkish. | Kose G, Bolu A, Ozdemir L, Acikel C, Hatipolu S | International journal of nursing knowledge | 2015 | |
| Innovative approach to measure delirium in hospitalized older adults using the electronic health record. | Khan A, Simpson M, Singh M, Hook M, Geng Y, Malone ML | Journal of the American Geriatrics Society | 2015 |
Aged, Cross-Sectional Studies, Delirium, diagnosis, Electronic Health Records, Female, Geriatric Assessment, Hospitalization, Humans, Male, Prospective Studies |
| Functional brain imaging in survivors of critical illness: A prospective feasibility study and exploration of the association between delirium and brain activation patterns. | Jackson JC, Morandi A, Girard TD, Merkle K, Graves AJ, Thompson JL, Shintani AK, Gunther ML, Cannistraci CJ, Rogers BP, Gore JC, Warrington HJ, Ely EW, Hopkins RO, | Journal of critical care | 2015 | |
| Smoking increases the risk of delirium for older inpatients: a prospective population-based study. | Hessler JB, Brönner M, Etgen T, Gotzler O, Förstl H, Poppert H, Sander D, Bickel H | General hospital psychiatry | 2015 | |
| Postoperative delirium is an independent risk factor for posttraumatic stress disorder in the elderly patient: a prospective observational study. | Drews T, Franck M, Radtke FM, Weiss B, Krampe H, Brockhaus WR, Winterer G, Spies CD | European journal of anaesthesiology | 2015 | |
| Preoperative education on postoperative delirium, anxiety, and knowledge in pulmonary thromboendarterectomy patients. | Chevillon C, Hellyar M, Madani C, Kerr K, Kim SC | American journal of critical care : an official publication, American Association of Critical-Care Nurses | 2015 | |
| Low hemoglobin level is associated with the development of delirium after hepatectomy for hepatocellular carcinoma patients. | Chen YL, Lin HC, Lin KH, Lin LS, Hsieh CE, Ko CJ, Hung YJ, Lin PY | PloS one | 2015 | |
| Melatonin and melatonin agonist for delirium in the elderly patients. | Chakraborti D, Tampi DJ, Tampi RR | American journal of Alzheimer's disease and other dementias | 2015 | |
| Postoperative Delirium in Patients Undergoing Total Joint Arthroplasty: A Systematic Review. | Bin Abd Razak HR, Yung WY | The Journal of arthroplasty | 2015 | |
| Risk factors for postoperative delirium in patients after coronary artery bypass grafting: A prospective cohort study. | Zhang WY, Wu WL, Gu JJ, Sun Y, Ye XF, Qiu WJ, Su CQ, Zhang SQ, Ye WQ | Journal of critical care | 2015 | |
| Symptom trends in the last year of life from 1998 to 2010: a cohort study. | Singer AE, Meeker D, Teno JM, Lynn J, Lunney JR, Lorenz KA | Annals of internal medicine | 2015 | |
| Functional Improvement Among Short-Stay Nursing Home Residents in the MDS 3.0. | Wysocki A, Thomas KS, Mor V | Journal of the American Medical Directors Association | 2015 | |
| Nonpharmacological interventions to prevent delirium: an evidence-based systematic review. | Rivosecchi RM, Smithburger PL, Svec S, Campbell S, Kane-Gill SL | Critical care nurse | 2015 | |
| A new delirium phenotype with rapid high amplitude onset and nearly as rapid reversal: Central Coast Australia Delirium Intervention Study. | Regal PJ | Clinical interventions in aging | 2015 | |
| Under-recognition of delirium in older adults by nurses in the intensive care unit setting. | Panitchote A, Tangvoraphonkchai K, Suebsoh N, Eamma W, Chanthonglarng B, Tiamkao S, Limpawattana P | Aging clinical and experimental research | 2015 | |
| Preoperative brain magnetic resonance imaging and postoperative delirium after off-pump coronary artery bypass grafting: a prospective cohort study. | Omiya H, Yoshitani K, Yamada N, Kubota Y, Takahashi K, Kobayashi J, Ohnishi Y | Canadian journal of anaesthesia = Journal canadien d'anesthesie | 2015 | |
| The Prevention and Treatment of Delirium in Elderly Patients Following Hip Fracture Surgery. | Martocchia A, Curto M, Comite F, Scaccianoce S, Girardi P, Ferracuti S, Nicoletti F, Falaschi P | Recent patents on CNS drug discovery | 2015 | |
| Prevention of post-operative delirium in older patients with cancer undergoing surgery. | Korc-Grodzicki B, Root JC, Alici Y | Journal of geriatric oncology | 2015 | |
| Effectiveness of multicomponent nonpharmacological delirium interventions: a meta-analysis. | Hshieh TT, Yue J, Oh E, Puelle M, Dowal S, Travison T, Inouye SK | JAMA internal medicine | 2015 |
Accidental Falls, statistics & numerical data, Confusion, etiology, Delirium, epidemiology, Humans, Incidence, Institutionalization, statistics & numerical data, Length of Stay, statistics & numerical data, Observer Variation, Odds Ratio, Quality of Life, Research Design, Treatment Outcome |
| Adult family member experiences during an older loved one's delirium: a narrative literature review. | Day J, Higgins I | Journal of clinical nursing | 2015 |
Adult, Aged, Caregivers, Delirium, nursing, Family, Health Services for the Aged, Humans, Narration, Nurse’s Role |
| Risk factors of delirium in patients undergoing total knee arthroplasty. | Chung KS, Lee JK, Park JS, Choi CH | Archives of gerontology and geriatrics | 2015 | |
| Automatic delirium prediction system and nursing-sensitive outcomes in the medical intensive care unit. | Cho HY, Song X, Piao J, Jin Y, Lee SM | Clinical nursing research | 2015 | |
| Evidence of and recommendations for non-pharmacological interventions for common geriatric conditions: the SENATOR-ONTOP systematic review protocol. | Abraha I, Cruz-Jentoft A, Soiza RL, O'Mahony D, Cherubini A | BMJ open | 2015 |