What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Comparison of Lurasidone Versus Quetiapine for the Treatment of Delirium in Critically Ill Patients.
- Authors
- Fox, M. A. Elefritz, J. L. Huang, B. M. Hunley, C.
- Year
- 2018
- Journal
- J Intensive Care Med
- Abstract
OBJECTIVE: To evaluate the efficacy and safety of lurasidone compared with quetiapine for treatment of delirium in critically ill patients. DESIGN: Prospective, observational cohort study. SETTING: Single-center community teaching hospital. PATIENTS: Forty adult intensive care unit (ICU) patients with delirium (Confusion Assessment Method in the ICU positive), tolerating enteral nutrition, and without active alcohol withdrawal or prior use of atypical antipsychotics. INTERVENTIONS: Patients were treated at the discretion of the prescriber with either lurasidone or quetiapine for delirium. Dose escalation and/or discontinuation were determined at the discretion of individual providers. RESULTS: Baseline characteristics differed with a higher severity of illness in patients in the quetiapine group (n = 20) and a higher baseline QTc interval in the lurasidone group (n = 20). No significant difference was seen in the time to delirium resolution (3.2 vs 3.4 days), average daily haloperidol requirements (5.7 vs 6.9 mg), hospital length of stay (LOS; 23.6 vs 27.9 days), or ICU LOS (12.1 vs 14.2 days). Lurasidone was associated with fewer ventilator support days (4.0 [interquartile range, IQR: 2.3-6.8] days vs 7 [IQR: 4.0-9.8; P = .0295] days) but also a fewer number of delirium-free days (0 [IQR: 0-1.0] days vs 2 [IQR: 0-3.0; P = .0231] days). Additionally, no difference was seen for ICU mortality (20% vs 20%), percentage of time oversedated (2.8% vs 2.7%), or incidence of QTc prolongation (10.0% vs 10.0%). CONCLUSIONS: Lurasidone for the treatment of delirium in critically ill patients did not differ in the time to delirium resolution when compared to quetiapine. Additionally, the incidence of QTc prolongation between agents does not appear to be different. Future randomized trials should evaluate dose escalation schemes and a larger proportion of patients to evaluate differences in mortality, efficacy, and life-threatening arrhythmias associated with atypical antipsychotic use.
- PMID
- Keywords
atypical antipsychotic
critical care
delirium
intensive care unit
lurasidone
quetiapine
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| How trained volunteers can improve the quality of hospital care for older patients. A qualitative evaluation within the Hospital Elder Life Program (HELP). | Steunenberg B, van der Mast RC, Strijbos MJ, Inouye SK, Schuurmans MJ | Geriatric nursing (New York, N.Y.) | 2016 | |
| Preventive strategies and potential therapeutic interventions for delirium in sepsis. | Souza-Dantas VC, Póvoa P, Bozza F, Soares M, Salluh J | Hospital practice (1995) | 2016 | |
| Delirium after transcatheter aortic valve implantation via the femoral or apical route. | Sharma V, Katznelson R, Horlick E, Osten M, Styra R, Cusimano RJ, Carroll J, Djaiani G | Anaesthesia | 2016 | |
| Paraneoplastic neuropsychiatric syndrome presenting as delirium. | Roldan Urgoiti G, Sinnarajah A, Hussain S, Hao D | BMJ supportive & palliative care | 2016 | |
| [Anticholinergic burden and delirium in elderly patients during acute hospital admission]. | Rojo-Sanchís AM, Vélez-Díaz-Pallarés M, Muñoz García M, Delgado Silveira E, Bermejo Vicedo T, Cruz Jentoft A | Revista española de geriatría y gerontología | 2016 | |
| Evaluation of the delirium early monitoring system (DEMS). | Rippon D, Milisen K, Detroyer E, Mukaetova-Ladinska E, Harrison B, Schuurmans M, Pryor C, Teodorczuk A | International psychogeriatrics / IPA | 2016 | |
| A Pilot Randomized Controlled Trial of the Feasibility of a Multicomponent Delirium Prevention Intervention Versus Usual Care in Acute Stroke. | Rice KL, Bennett MJ, Berger L, Jennings B, Eckhardt L, Fabré-LaCoste N, Houghton D, Vidal G, Gropen T, Diggs E, Barry E, St John J, Mathew S, Egger A, Ryan S, Egger R, Galarneau D, Gaines K, Ely EW | The Journal of cardiovascular nursing | 2016 | |
| Delirium After Major Elective Noncardiac Surgery: Successful Aging After Elective Surgery Study. | Regal PJ | Journal of the American Geriatrics Society | 2016 | |
| Delirium in Survivors of Cardiac Arrest Treated With Mild Therapeutic Hypothermia. | Pollock JS, Hollenbeck RD, Wang L, Holmes B, Young MN, Peters M, Ely EW, McPherson JA, Vasilevskis EE | American journal of critical care : an official publication, American Association of Critical-Care Nurses | 2016 | |
| The Impact of Plasma Cholinergic Enzyme Activity and Other Risk Factors for the Development of Delirium in Patients Receiving Palliative Care. | Plaschke K, Petersen KA, Frankenhauser S, Weigand MA, Kopitz J, Bardenheuer HJ | Journal of pain and symptom management | 2016 | |
| Triggers and nursing influences on delirium in intensive care units. | Piao J, Jin Y, Lee SM | Nursing in critical care | 2016 | |
| Battery of behavioral tests in mice to study postoperative delirium. | Peng M, Zhang C, Dong Y, Zhang Y, Nakazawa H, Kaneki M, Zheng H, Shen Y, Marcantonio ER, Xie Z | Scientific reports | 2016 | |
| Delirium associated with olanzapine use in the elderly. | Park JI | Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society | 2017 | |
| Are stroke survivors with delirium at higher risk of post-stroke dementia? Current evidence and future directions. | Ojagbemi A, Ffytche DH | International journal of geriatric psychiatry | 2016 | |
| Detecting Delirium Superimposed on Dementia: Evaluation of the Diagnostic Performance of the Richmond Agitation and Sedation Scale. | Morandi A, Han JH, Meagher D, Vasilevskis E, Cerejeira J, Hasemann W, MacLullich AM, Annoni G, Trabucchi M, Bellelli G | Journal of the American Medical Directors Association | 2016 | |
| Prediction of Postoperative Complications Following Elective Surgery in Elderly Patients with Colorectal Cancer Using the Comprehensive Geriatric Assessment. | Mokutani Y, Mizushima T, Yamasaki M, Rakugi H, Doki Y, Mori M | Digestive surgery | 2016 | |
| Melatonin Supplementation to Prevent Delirium in Hospitalized Elderly Patients. | Messerschmidt K | South Dakota medicine : the journal of the South Dakota State Medical Association | 2016 | |
| Dexmedetomidine and delirium in the ICU. | McLaughlin M, Marik PE | Annals of translational medicine | 2016 | |
| Quiet time for mechanically ventilated patients in the medical intensive care unit. | McAndrew NS, Leske J, Guttormson J, Kelber ST, Moore K, Dabrowski S | Intensive & critical care nursing | 2016 | |
| Neural substrates of vulnerability to post-surgical delirium with prospective diagnosis. | Lindroth H, Sanders RD | Brain : a journal of neurology | 2016 | |
| Documentation of Capacity Assessment and Subsequent Consent in Patients Identified With Delirium. | Lamont S, Stewart C, Chiarella M | Journal of bioethical inquiry | 2016 | |
| Relationship Between African-American Race and Delirium in the ICU. | Khan BA, Perkins A, Hui SL, Gao S, Campbell NL, Farber MO, Boustani MA | Critical care medicine | 2016 | |
| Understanding cognition in older patients with cancer. | Karuturi M, Wong ML, Hsu T, Kimmick GG, Lichtman SM, Holmes HM, Inouye SK, Dale W, Loh KP, Whitehead MI, Magnuson A, Hurria A, Janelsins MC, Mohile S | Journal of geriatric oncology | 2016 | |
| Clinical Frailty Scale in an Acute Medicine Unit: a Simple Tool That Predicts Length of Stay. | Juma S, Taabazuing MM, Montero-Odasso M | Canadian geriatrics journal : CGJ | 2016 | |
| Prevalence of Delirium and Coma In Mechanically Ventilated Patients Sedated With Dexmedetomidine or Propofol. | Jiang YK, Wang S, Lam TS, Hanna A, DeMuro JP, Calixte R, Brathwaite CE | P & T : a peer-reviewed journal for formulary management | 2016 | |
| Association of pre-operative medication use with post-operative delirium in surgical oncology patients receiving comprehensive geriatric assessment. | Jeong YM, Lee E, Kim KI, Chung JE, In Park H, Lee BK, Gwak HS | BMC geriatrics | 2016 | |
| Impact of delirium on weaning from mechanical ventilation in medical patients - Reply. | Jeon K | Respirology (Carlton, Vic.) | 2016 | |
| Underestimated factors may also precipitate delirium and can lead to the misinterpretation of frailty in these patients. | İlhan B, Tufan F, Bahat G, Karan MA | Clinical interventions in aging | 2016 | |
| Examining the Hospital Elder Life Program in a rehabilitation setting: a pilot feasibility study. | Huson K, Stolee P, Pearce N, Bradfield C, Heckman GA | BMC geriatrics | 2016 | |
| Hypothyroidism may exacerbate valproate-related hyperammonemic delirium. | Hung CC, Lin CH, Lane HY | BioMedicine | 2016 | |
| Testing the functional assessment of mentation: A mobile application based assessment of mental status. | Hamilton DE, Press VG, Twu NM, Yuen TC, Azu CN, Churpek MM, Edelson DP | Journal of hospital medicine | 2016 | |
| Delirium frequency among advanced cancer patients presenting to an emergency department: A prospective, randomized, observational study. | Elsayem AF, Bruera E, Valentine AD, Warneke CL, Yeung SC, Page VD, Wood GL, Silvestre J, Holmes HM, Brock PA, Todd KH | Cancer | 2016 | |
| Long-Term Effects of Postoperative Delirium in Patients Undergoing Cardiac Operation: A Systematic Review. | Crocker E, Beggs T, Hassan A, Denault A, Lamarche Y, Bagshaw S, Elmi-Sarabi M, Hiebert B, Macdonald K, Giles-Smith L, Tangri N, Arora RC | The Annals of thoracic surgery | 2016 | |
| Development of guidelines for family and non-professional helpers on assisting an older person who is developing cognitive impairment or has dementia: a Delphi expert consensus study. | Bond KS, Jorm AF, Kitchener BA, Kelly CM, Chalmers KJ | BMC geriatrics | 2016 | |
| Volunteers improving person-centred dementia and delirium care in a rural Australian hospital. | Bateman C, Anderson K, Bird M, Hungerford C | Rural and remote health | 2016 | |
| Predictors of Mortality for Delirium in Palliative Care. | Agar MR, Quinn SJ, Crawford GB, Ritchie CS, Phillips JL, Collier A, Currow DC | Journal of palliative medicine | 2016 | |
| Validation of the Critical Care Pain Observation Tool in Critically Ill Patients With Delirium: A Prospective Cohort Study. | Kanji S, MacPhee H, Singh A, Johanson C, Fairbairn J, Lloyd T, MacLean R, Rosenberg E | Critical care medicine | 2016 | |
| Undiagnosed long-term cognitive impairment in acutely hospitalised older medical patients with delirium: a prospective cohort study. | Jackson TA, MacLullich AM, Gladman JR, Lord JM, Sheehan B | Age and ageing | 2016 | |
| A systematic review and meta-analysis of the association between the apolipoprotein E genotype and delirium. | Adamis D, Meagher D, Williams J, Mulligan O, McCarthy G | Psychiatric genetics | 2016 | |
| Stop. Think. Delirium! A quality improvement initiative to explore utilising a validated cognitive assessment tool in the acute inpatient medical setting to detect delirium and prompt early intervention. | Malik A, Harlan T, Cobb J | Journal of clinical nursing | 2016 | |
| Slow Gait Speed and Rapid Renal Function Decline Are Risk Factors for Postoperative Delirium after Urological Surgery. | Sato T, Hatakeyama S, Okamoto T, Yamamoto H, Hosogoe S, Tobisawa Y, Yoneyama T, Hashiba E, Yoneyama T, Hashimoto Y, Koie T, Hirota K, Ohyama C | PloS one | 2016 | |
| The short-term and long-term relationship between delirium and cognitive trajectory in older surgical patients. | Inouye SK, Marcantonio ER, Kosar CM, Tommet D, Schmitt EM, Travison TG, Saczynski JS, Ngo LH, Alsop DC, Jones RN | Alzheimer's & dementia : the journal of the Alzheimer's Association | 2016 | |
| A Serious Game for Clinical Assessment of Cognitive Status: Validation Study. | Tong T, Chignell M, Tierney MC, Lee J | JMIR serious games | 2016 | |
| Review of Postoperative Delirium in Geriatric Patients Undergoing Hip Surgery. | Rizk P, Morris W, Oladeji P, Huo M | Geriatric orthopaedic surgery & rehabilitation | 2016 | |
| Regional versus general anaesthesia in elderly patients undergoing surgery for hip fracture: protocol for a systematic review. | Yeung J, Patel V, Champaneria R, Dretzke J | Systematic reviews | 2016 | |
| The Prevalence of Undiagnosed Presurgical Cognitive Impairment and Its Postsurgical Clinical Impact in Older Patients Undergoing Lumbar Spine Surgery. | Lee YS, Kim YB, Lee SH, Park YS, Park SW | Journal of Korean Neurosurgical Society | 2016 | |
| A Preoperative, Nurse-Led Intervention Program Reduces Acute Postoperative Delirium. | Guo Y, Fan Y | The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses | 2016 | |
| Preliminary Data: An Adapted Hospital Elder Life Program to Prevent Delirium and Reduce Complications of Acute Illness in Long-Term Care Delivered by Certified Nursing Assistants. | Boockvar KS, Teresi JA, Inouye SK | Journal of the American Geriatrics Society | 2016 | |
| Predicting delirium after hip fracture with a 2-min cognitive screen: prospective cohort study. | Fortes-Filho SQ, Apolinario D, Melo JA, Suzuki I, Sitta Mdo C, Garcez Leme LE | Age and ageing | 2016 | |
| The PiTSTOP study: a feasibility cluster randomized trial of delirium prevention in care homes for older people. | Siddiqi N, Cheater F, Collinson M, Farrin A, Forster A, George D, Godfrey M, Graham E, Harrison J, Heaven A, Heudtlass P, Hulme C, Meads D, North C, Sturrock A, Young J | Age and ageing | 2016 | |
| Pilot study of a preventive multicomponent nurse intervention to reduce the incidence and severity of delirium in hospitalized older adults: MID-Nurse-P. | Avendaño-Céspedes A, García-Cantos N, González-Teruel Mdel M, Martínez-García M, Villarreal-Bocanegra E, Oliver-Carbonell JL, Abizanda P | Maturitas | 2016 | |
| Olfactory dysfunction is related to postoperative delirium in Parkinson's disease. | Kim MS, Yoon JH, Kim HJ, Yong SW, Hong JM | Journal of neural transmission (Vienna, Austria : 1996) | 2016 | |
| Mum's absence(s): conceptual insights into absence as loss during a loved one's delirium. | Day J, Higgins I | Journal of clinical nursing | 2016 | |
| Mortality Risk of Antipsychotic Dose and Duration in Nursing Home Residents with Chronic or Acute Indications. | Simoni-Wastila L, Wei YJ, Lucas JA, Brandt N, Moyo P, Huang TY, Franey CS, Harris I | Journal of the American Geriatrics Society | 2016 | |
| Mental Capacity Assessments Among Inpatients Referred to the Consultation-Liaison Psychiatry Unit at a University Hospital in Bangkok, Thailand. | Pariwatcharakul P, Singhakant S | The Psychiatric quarterly | 2016 | |
| Length of Stay in the Emergency Department and Occurrence of Delirium in Older Medical Patients. | Bo M, Bonetto M, Bottignole G, Porrino P, Coppo E, Tibaldi M, Ceci G, Raspo S, Cappa G, Bellelli G | Journal of the American Geriatrics Society | 2016 | |
| Lack of Association between Pre-Operative Insulin-Like Growth Factor-1 and the Risk of Post-Operative Delirium in Elderly Chinese Patients. | Chu CS, Liang CK, Chou MY, Lin YT, Hsu CJ, Chu CL, Chou PH | Psychiatry investigation | 2016 | |
| Is longer storage time of red blood cells really not associated with risks of delirium and complications after hip fracture surgery? | Xue FS, Liu GP, Yang GZ, Sun C | Injury | 2016 | |
| Inter-professional delirium education and care: a qualitative feasibility study of implementing a delirium Smartphone application. | Zhang M, Bingham K, Kantarovich K, Laidlaw J, Urbach D, Sockalingam S, Ho R | BMC medical informatics and decision making | 2016 |
Adult, Delirium, Education, Continuing, methods, Feasibility Studies, Humans, Interdisciplinary Communication, Mobile Applications, Qualitative Research, Smartphone |
| Increasing delirium skills at the front door: results from a repeated survey on delirium knowledge and attitudes. | Jenkin RP, Al-Attar A, Richardson S, Myint PK, MacLullich AM, Davis DH | Age and ageing | 2016 | |
| Incidence and risk factors for postoperative delirium after major head and neck cancer surgery. | Booka E, Kamijo T, Matsumoto T, Takeuchi M, Kitani T, Nagaoka M, Imai A, Iida Y, Shimada A, Takebayashi K, Niihara M, Mori K, Onitsuka T, Tsubosa Y, Takeuchi H, Kitagawa Y | Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery | 2016 | |
| Impact of non-pharmacological interventions on prevention and treatment of delirium in critically ill patients: protocol for a systematic review of quantitative and qualitative research. | Bannon L, McGaughey J, Clarke M, McAuley DF, Blackwood B | Systematic reviews | 2016 | |
| Impact of delirium on weaning from mechanical ventilation in medical patients. | Jeon K, Jeong BH, Ko MG, Nam J, Yoo H, Chung CR, Suh GY | Respirology (Carlton, Vic.) | 2016 | |
| I Can Remember Sort of Vivid People…but to Me They Were Plasticine." Delusions on the Intensive Care Unit: What Do Patients Think Is Going On? | Darbyshire JL, Greig PR, Vollam S, Young JD, Hinton L | PloS one | 2016 | |
| How do healthcare workers judge pain in older palliative care patients with delirium near the end of life? | Gagliese L, Rodin R, Chan V, Stevens B, Zimmermann C | Palliative & supportive care | 2016 |
Aged, Aged, 80 and over, Clinical Competence, standards, Delirium, therapy, Female, Humans, Male, Neoplasms, complications, Nurses, psychology, Pain, diagnosis, Palliative Care, methods, Prevalence, Retrospective Studies |
| Genetic and environmental factors associated with delirium severity in older adults with dementia. | Massimo L, Munoz E, Hill N, Mogle J, Mulhall P, McMillan CT, Clare L, Vandenbergh D, Fick D, Kolanowski A | International journal of geriatric psychiatry | 2017 | |
| Falls in A Tertiary Care Hospital-Association With Delirium: A Replication Study. | Babine RL, Hyrkäs KE, Bachand DA, Chapman JL, Fuller VJ, Honess CA, Wierman HR | Psychosomatics | 2016 | |
| The experiences of caregivers of patients with delirium, and their role in its management in palliative care settings: an integrative literature review. | Finucane AM, Lugton J, Kennedy C, Spiller JA | Psycho-oncology | 2017 | |
| Endothelial Activation and Blood-Brain Barrier Injury as Risk Factors for Delirium in Critically Ill Patients. | Hughes CG, Pandharipande PP, Thompson JL, Chandrasekhar R, Ware LB, Ely EW, Girard TD | Critical care medicine | 2016 | |
| Effects of Intraoperative Hemodynamics on Incidence of Postoperative Delirium in Elderly Patients: A Retrospective Study. | Yang L, Sun DF, Han J, Liu R, Wang LJ, Zhang ZZ | Medical science monitor : international medical journal of experimental and clinical research | 2016 | |
| The Effects of Blood Transfusion on Delirium Incidence. | van der Zanden V, Beishuizen SJ, Scholtens RM, de Jonghe A, de Rooij SE, van Munster BC | Journal of the American Medical Directors Association | 2016 | |
| Diagnostic test accuracy of informant-based tools to diagnose dementia in older hospital patients with delirium: a prospective cohort study. | Jackson TA, MacLullich AM, Gladman JR, Lord JM, Sheehan B | Age and ageing | 2016 | |
| The development of an automated ward independent delirium risk prediction model. | de Wit HA, Winkens B, Mestres Gonzalvo C, Hurkens KP, Mulder WJ, Janknegt R, Verhey FR, van der Kuy PH, Schols JM | International journal of clinical pharmacy | 2016 | |
| Detecting delirium in elderly outpatients with cognitive impairment. | Stroomer-van Wijk AJ, Jonker BW, Kok RM, van der Mast RC, Luijendijk HJ | International psychogeriatrics / IPA | 2016 | |
| Delirium in the geriatric unit: proton-pump inhibitors and other risk factors. | Otremba I, Wilczyński K, Szewieczek J | Clinical interventions in aging | 2016 | |
| Delirium diagnosis defined by cluster analysis of symptoms versus diagnosis by DSM and ICD criteria: diagnostic accuracy study. | Sepulveda E, Franco JG, Trzepacz PT, Gaviria AM, Meagher DJ, Palma J, Viñuelas E, Grau I, Vilella E, de Pablo J | BMC psychiatry | 2016 | |
| Delirium as a Predictor of Physical and Cognitive Function in Individuals Aged 80 and Older After Transcatheter Aortic Valve Implantation or Surgical Aortic Valve Replacement. | Eide LS, Ranhoff AH, Fridlund B, Haaverstad R, Hufthammer KO, Kuiper KK, Nordrehaug JE, Norekvål TM, | Journal of the American Geriatrics Society | 2016 | |
| Current approach to diagnosis and treatment of delirium after cardiac surgery. | Evans AS, Weiner MM, Arora RC, Chung I, Deshpande R, Varghese R, Augoustides J, Ramakrishna H | Annals of cardiac anaesthesia | 2016 | |
| Comparison of diagnostic classification systems for delirium with new research criteria that incorporate the three core domains. | Trzepacz PT, Meagher DJ, Franco JG | Journal of psychosomatic research | 2016 | |
| Cognitive assessment of older adults at the acute care interface: the informant history. | Dyer AH, Nabeel S, Briggs R, O'Neill D, Kennelly SP | Postgraduate medical journal | 2016 | |
| Can the critical-care pain observation tool (CPOT) be used to assess pain in delirious ICU patients? | Rijkenberg S, van der Voort PH | Journal of thoracic disease | 2016 | |
| Utility of neuropsychological tests in predicting post-operative delirium following elective primary arthroplasty | Cunningham, E. L. | Alzheimer's and Dementia | 2016 |
aged |
| Frailty as a predictor for poorer outcomes among older adults admitted to a specialised delirium unit | Chew, J. | Annals of the Academy of Medicine Singapore |
adult |
|
| Improved quality of care of older patients experiencing a delirium within the acute hospital setting: A quality improvement project | Chapman, J. | European Geriatric Medicine | 2016 | |
| Delirium in an intensive care setting | Becker, A. | Intensiv- und Notfallbehandlung | 2016 | |
| Delirium recognition in older people using a validated assessment tool (Confusion Assessment Method, CAM) improves rates of diagnosis, communication and the overall quality of care | Akintade, O. | European Geriatric Medicine | 2016 | |
| Influence of a Delirium Education Program on Intensive Care Nurses' Knowledge Regarding Delirium Identification and Mitigation | Shirley Marr | Canadian Journal of Critical Care Nursing | 2016 |
delirium education research change |
| Dynamics of Critical Care 2016 in Charlottetown, PE, September 25-27, 2016 | Sharon Hickin, Sandy White | Canadian Journal of Critical Care Nursing | 2016 |
ICU Psychosis — Prevention and Control |
| [Role of α7 nicotinic acetylcholine receptor in attenuation of endotoxin induced delirium with dexmedetomidine in mice]. | Zhang X, Li Z, Sun X, Jin F, Liu J, Li J | Zhonghua wei zhong bing ji jiu yi xue | 2016 |
Acetylcholinesterase, metabolism, Animals, Bungarotoxins, adverse effects, Choline O-Acetyltransferase, metabolism, Delirium, chemically induced, Dexmedetomidine, therapeutic use, Endotoxemia, chemically induced, Endotoxins, adverse effects, Hippocampus, drug effects, Lipopolysaccharides, Male, Mice, Mice, Inbred C57BL, Phosphopyruvate Hydratase, metabolism, Random Allocation, Tumor Necrosis Factor-alpha, metabolism, alpha7 Nicotinic Acetylcholine Receptor, metabolism |
| Chasing the Mirage: a grounded theory of the clinical reasoning processes that Registered Nurses use to recognize delirium. | El Hussein M, Hirst S | Journal of advanced nursing | 2016 |
Adult, Aged, Aged, 80 and over, Alberta, Clinical Competence, Critical Care Nursing, methods, Delirium, diagnosis, Female, Grounded Theory, Humans, Male, Middle Aged, Nursing Assessment, Nursing Care, psychology, Nursing Staff, Hospital, psychology, Thinking |
| The effect of an interactive delirium e-learning tool on healthcare workers' delirium recognition, knowledge and strain in caring for delirious patients: a pilot pre-test/post-test study. | Detroyer E, Dobbels F, Debonnaire D, Irving K, Teodorczuk A, Fick DM, Joosten E, Milisen K | BMC medical education | 2016 |
Clinical Competence, Computer-Assisted Instruction, methods, Delirium, diagnosis, Education, Professional, methods, Female, Health Knowledge, Attitudes, Practice, Health Personnel, education, Humans, Internet, Male, Pilot Projects, Sampling Studies |
| DEL-FINE: a new tool for assessing the delirogenic properties of drugs of relevance for European pharmacotherapy. | Böhmdorfer B, Rohleder S, Wawruch M, van der Cammen TJ, Frühwald T, Jagsch C, Janowitz SM, Nagano M, Petrovic M, Sommeregger U, Iglseder B | Zeitschrift fur Gerontologie und Geriatrie | 2016 |
Anticholinergic Syndrome, etiology, Delirium, chemically induced, Delphi Technique, Drug Therapy, standards, Europe, Expert Testimony, methods, Humans, Practice Guidelines as Topic |
| Consciousness, Functional networks and Delirium screening. | Eeles E, Burianova H, Pandy S, Pinsker D | Current aging science | 2016 | |
| Delirium: A Survey of Healthcare Professionals' Knowledge, Beliefs, and Practices. | Sinvani L, Kozikowski A, Pekmezaris R, Akerman M, Wolf-Klein G | Journal of the American Geriatrics Society | 2016 | |
| Low dose dexmedetomidine for the prophylaxis of perioperative ICU delirium-how much evidence is enough? | Reade MC | Journal of thoracic disease | 2016 | |
| [Study of prevention and control of delirium in ventilated patients by simulating blockage of circadian rhythm with sedative in intensive care unit]. | Li J, Dong C, Zhang H, Zhang H, Song R, Yang Z, Feng F, Qi Y, Yang J | Zhonghua wei zhong bing ji jiu yi xue | 2016 |
Analgesics, Circadian Rhythm, Critical Care, Delirium, Dexmedetomidine, Fentanyl, Humans, Hypnotics and Sedatives, Intensive Care Units, Pain, Propofol, Prospective Studies, Respiration, Artificial |
| Effect of Cognitively Stimulating Activities on Symptom Management of Delirium Superimposed on Dementia: A Randomized Controlled Trial. | Kolanowski A, Fick D, Litaker M, Mulhall P, Clare L, Hill N, Mogle J, Boustani M, Gill D, Yevchak-Sillner A | Journal of the American Geriatrics Society | 2016 | |
| Dexmedetomidine for prevention of delirium in elderly patients after non-cardiac surgery. | Karren EA, King AB, Hughes CG | Journal of thoracic disease | 2016 | |
| Decreased Incidence of Postoperative Delirium in Robot-assisted Thoracoscopic Esophagectomy Compared With Open Transthoracic Esophagectomy. | Jeong DM, Kim JA, Ahn HJ, Yang M, Heo BY, Lee SH | Surgical laparoscopy, endoscopy & percutaneous techniques | 2016 | |
| Delirium in the Neuro Intensive Care Unit. | Haymore JB, Patel N | Critical care nursing clinics of North America | 2016 |
Brief Psychiatric Rating Scale, Critical Care, Delirium, physiopathology, Humans, Intensive Care Units, Nursing Assessment, Pain Management |