What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Prevalence and risk factors for delirium in critically ill patients with COVID-19 (COVID-D): a multicentre cohort study
- Authors
- Pun, B. T. Badenes, R. Heras La Calle, G. Orun, O. M. Chen, W. Raman, R. Simpson, B. K. Wilson-Linville, S. Hinojal Olmedillo, B. Vallejo de la Cueva, A. van der Jagt, M. Navarro Casado, R. Leal Sanz, P. Orhun, G. Ferrer Gómez, C. Núñez Vázquez, K. Pi
- Year
- 2021
- Journal
- Lancet Respir Med
- Abstract
BACKGROUND: To date, 750 000 patients with COVID-19 worldwide have required mechanical ventilation and thus are at high risk of acute brain dysfunction (coma and delirium). We aimed to investigate the prevalence of delirium and coma, and risk factors for delirium in critically ill patients with COVID-19, to aid the development of strategies to mitigate delirium and associated sequelae. METHODS: This multicentre cohort study included 69 adult intensive care units (ICUs), across 14 countries. We included all patients (aged ≥18 years) admitted to participating ICUs with severe acute respiratory syndrome coronavirus 2 infection before April 28, 2020. Patients who were moribund or had life-support measures withdrawn within 24 h of ICU admission, prisoners, patients with pre-existing mental illness, neurodegenerative disorders, congenital or acquired brain damage, hepatic coma, drug overdose, suicide attempt, or those who were blind or deaf were excluded. We collected de-identified data from electronic health records on patient demographics, delirium and coma assessments, and management strategies for a 21-day period. Additional data on ventilator support, ICU length of stay, and vital status was collected for a 28-day period. The primary outcome was to determine the prevalence of delirium and coma and to investigate any associated risk factors associated with development of delirium the next day. We also investigated predictors of number of days alive without delirium or coma. These outcomes were investigated using multivariable regression. FINDINGS: Between Jan 20 and April 28, 2020, 4530 patients with COVID-19 were admitted to 69 ICUs, of whom 2088 patients were included in the study cohort. The median age of patients was 64 years (IQR 54 to 71) with a median Simplified Acute Physiology Score (SAPS) II of 40·0 (30·0 to 53·0). 1397 (66·9%) of 2088 patients were invasively mechanically ventilated on the day of ICU admission and 1827 (87·5%) were invasively mechanical ventilated at some point during hospitalisation. Infusion with sedatives while on mechanical ventilation was common: 1337 (64·0%) of 2088 patients were given benzodiazepines for a median of 7·0 days (4·0 to 12·0) and 1481 (70·9%) were given propofol for a median of 7·0 days (4·0 to 11·0). Median Richmond Agitation-Sedation Scale score while on invasive mechanical ventilation was -4 (-5 to -3). 1704 (81·6%) of 2088 patients were comatose for a median of 10·0 days (6·0 to 15·0) and 1147 (54·9%) were delirious for a median of 3·0 days (2·0 to 6·0). Mechanical ventilation, use of restraints, and benzodiazepine, opioid, and vasopressor infusions, and antipsychotics were each associated with a higher risk of delirium the next day (all p≤0·04), whereas family visitation (in person or virtual) was associated with a lower risk of delirium (p<0·0001). During the 21-day study period, patients were alive without delirium or coma for a median of 5·0 days (0·0 to 14·0). At baseline, older age, higher SAPS II scores, male sex, smoking or alcohol abuse, use of vasopressors on day 1, and invasive mechanical ventilation on day 1 were independently associated with fewer days alive and free of delirium and coma (all p<0·01). 601 (28·8%) of 2088 patients died within 28 days of admission, with most of those deaths occurring in the ICU. INTERPRETATION: Acute brain dysfunction was highly prevalent and prolonged in critically ill patients with COVID-19. Benzodiazepine use and lack of family visitation were identified as modifiable risk factors for delirium, and thus these data present an opportunity to reduce acute brain dysfunction in patients with COVID-19. FUNDING: None. TRANSLATIONS: For the French and Spanish translations of the abstract see Supplementary Materials section.
- PMID
- Keywords
Aged
COVID-19/ psychology
Coma/ epidemiology/virology
Critical Illness/psychology
Delirium/ epidemiology/virology
Female
Humans
Hypnotics and Sedatives/therapeutic use
Intensive Care Units/statistics & numerical data
Male
Middle Aged
Prevalence
Respiration, Artificial/psychology/statistics & numerical data
Retrospective Studies
Risk Factors
SARS-CoV-2
- Page(s)
- 239-250
- Volume
- 9
- Issue
- 3
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Effect of clock rhythm on emergence agitation and early postoperative delirium in older adults undergoing thoracoscopic lung cancer surgery: protocol for a prospective, observational, cohort study | Jiang, L. Wang, J. Chen, W. Wang, Z. Xiong, W. | BMC Geriatr | 2024 |
Humans |
| Scientific rationale for the use of α2A-adrenoceptor agonists in treating neuroinflammatory cognitive disorders | Arnsten, A. F. T. Ishizawa, Y. Xie, Z. | Mol Psychiatry | 2023 |
Humans |
| The role of perioperative sedative anesthetics in preventing postoperative delirium: a systematic review and network-meta analysis including 6679 patients | Huang, J. X. Zhang, S. S. Wang, S. X. Xi, D. S. Luo, F. R. Liu, C. J. Li, H. | BMC Cardiovasc Disord | 2024 |
PMID: 38448835 PMCID: PMC10916082 |
| Preventive Effects of Melatonin on Delirium in Intensive Care Unit Patients: A Meta-Analysis of Randomized Controlled Trials | Zhao, L. Feng, Z. Wang, Q. Jiang, Z. Qiu, X. | Altern Ther Health Med | 2024 |
ICU Delirium Melatonin Length of Stay Meta-Analysis Mechanical Ventilation |
| Mitochondrial Dysfunction of Peripheral Platelets as a Predictive Biomarker for Postoperative Delirium in Elderly Patients | Yang, Y. Zhang, W. Liu, Y. Liu, X. Xie, J. Xu, R. Huang, Y. Hao, J. Sun, Y. Gu, X. Ma, Z. | Ann Neurol | 2024 |
Postoperative Delirium Bioenergetic Health Index Surgery Mitochondria MMSE
|
| Effect of Esketamine on Postoperative Delirium in Patients Undergoing Cardiac Valve Replacement with Cardiopulmonary Bypass: A Randomized Controlled Trial | Xiong, X. Shao, Y. Chen, D. Chen, B. Lan, X. Shi, J. | Anesth Analg | 2024 |
Postoperative Delirium Esketamine Cardiac Valve Replacement Cardiopulmonary Bypass CAM CAM-ICU MMSE |
| Prolonged Hourly Neurologic Examinations are Associated with Increased Delirium and No Discernible Benefit in Mild/Moderate Geriatric Traumatic Brain Injury | Ruiz, R. A. F. Canas, M. Diaz, L. Aldana, J. A. Afzal, H. Falcon, A. F. Del Toro, D. Day, A. McCarthy, J. Stansfield, K. Bochicchio, G. V. Niziolek, G. Kranker, L. M. Rosengart, M. R. Hoofnagle, M. Leonard, J. | J Trauma Acute Care Surg | 2024 |
NeuroChecks Delirium TBI CAM-ICU |
| Association of Intravenous Neostigmine and Anticholinergics or Sugammadex with Postoperative Delirium: A Retrospective Cohort Study | Rössler, J. Abramczyk, E. Paredes, S. Anusic, N. Pu, X. Maheshwari, K. Turan, A. Ruetzler, K. | Anesth Analg | 2024 |
bCAM Postoperative Delirium Sugammadex Neostigmine Anesthesia Noncardiac Surgery |
| Metformin Use in Type 2 Diabetics and Delirium After Noncardiac Surgery: A Retrospective Cohort Analysis | Paredes, S. Harb, A. Rössler, J. Nikoo, M. Z. Ruetzler, K. Turan, A. Pu, X. Sessler, D. I. | Anesth Analg | 2024 |
Type 2 Diabetes CAM-ICU bCAM Postoperative Delirium Metformin
|
| Preoperative Intrathecal Morphine is Associated With Reduced Postoperative Pain, Agitation, and Delirium In Living Donor Kidney Transplantation Recipients | Lee, J. E. Lee, K. W. Gil, E. Park, J. B. Kim, B. J. Kim, H. Y. Kim, G. S. | Transplant Proc | 2024 |
Kidney Transplant Postoperative Delirium Intrathecal Morphine CAM-ICU Postoperative Pain Anesthesia |
| Neuropsychological follow-up of isoflurane sedated intensive care patients: a substudy of a randomized trial | Fuchs, V. F. Simon, H. V. Soldinger, N. Volk, T. Meiser, A. | Minerva Anestesiol | 2024 |
Critical care Isoflurane Propofol Delirium |
| Feasibility and Acceptability of Using Wireless Limited Polysomnography to Capture Sleep Before, During, and After Hospitalization for Patients With Planned Cardiothoracic Surgery | Cordoza, M. L. Anderson, B. J. Cevasco, M. Diamond, J. M. Younes, M. Gerardy, B. Iroegbu, C. Riegel, B. | J Cardiovasc Nurs | 2024 |
Critical Illness Intensive Care Unit Polysomnography Sleep Thoracic Surgery |
| Antipsychotics in the Treatment of Delirium in Critically Ill Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials | Carayannopoulos, K. L. Alshamsi, F. Chaudhuri, D. Spatafora, L. Piticaru, J. Campbell, K. Alhazzani, W. Lewis, K. | Crit Care Med | 2024 |
Antipsychotic medication Delirium Systematic review Critically Ill Cognitive Impairment Coma |
| Burnout and perceived burden levels related to delirium in physicians and nurses | Yamagata, H. Takihara, T. Kobayashi, R. Hirose, K. Higuchi, K. Miyahara, M. Komatsu, D. | Gen Hosp Psychiatry | 2024 |
Humans |
| Bell's mania as a clinical presentation in a neurosurgical setting from a tertiary care neuropsychiatric hospital in India | Mamtani, H. Utagi, S. Chaurasia, K. K. Reddy, P. V. Arasappa, R. Prasad, C. Srinivas, D. Rao, M. B. Thippeswamy, H. | Indian J Psychiatry | 2024 |
Craniopharyngioma |
| Correlation analysis between plasma biomarkers albumin, fibrinogen, and their ratio with postoperative delirium in patients undergoing non-cardiac surgery: a systematic review and meta-analysis | Lu, Z. Wang, B. Liu, M. Yu, D. Li, J. | Am J Transl Res | 2024 |
Albumin |
| Risk factors for hypoactive delirium in patients with nontraumatic ARDS: a prospective observational study | Lian, F. Li, F. Tang, X. Yuan, Y. | Sci Rep | 2024 |
Humans |
| Current Practices and Attitudes of Cardiac Nurses Regarding Cognitive Screening in Patients With Acute Coronary Syndrome | Zhao, E. Lowres, N. Bloomfield, J. Weddell, J. Tofler, G. Gallagher, R. | Heart Lung Circ | 2024 |
Acute coronary syndrome |
| Related factors of delirium after transsphenoidal endoscopic pituitary adenoma resection-A matched retrospective cohort study | Zhang, S. Chen, Y. Wang, X. Liu, J. Chen, Y. Zhang, G. | J Clin Neurosci | 2024 |
Neuroendoscopy |
| Prevalence of post-stroke delirium in acute settings: A systematic review and meta-analysis | Ye, F. Ho, M. H. Lee, J. J. | Int J Nurs Stud | 2024 |
Acute setting |
| Predictive factors for postoperative delirium in thoracic surgery | Yaguchi, T. Ichinokawa, H. Kirino, E. Suzuki, M. Komori, K. Matsunaga, T. Takamochi, K. Suzuki, K. | Gen Thorac Cardiovasc Surg | 2024 |
Postoperative delirium |
| Preoperative cognitive impairment and postoperative delirium among Holocaust survivors who achieved longevity | Weiss, Y. Zarour, S. Kiselevich, Y. Abu Ghanim, M. Hikry, D. Sinai Brzezinski, I. Zac, L. Cohen, B. Matot, I. | J Am Geriatr Soc | 2024 |
Holocaust |
| Substance use problems and disorders among adults 50 years and older receiving mental health treatment for a primary neurocognitive disorder | Ware, O. D. Baik, S. Becker, T. D. Neukrug, H. Zimmerman, S. | Aging Ment Health |
Aging |
|
| The risk of delirium after sedation with propofol or midazolam in intensive care unit patients | van Gelder, T. G. van Diem-Zaal, I. J. Dijkstra-Kersten, S. M. A. de Mul, N. Lalmohamed, A. Slooter, A. J. C. | Br J Clin Pharmacol | 2024 |
critical care |
| Incidence and Risk Factors for ICU-Associated Delirium in the Alert Geriatric Trauma Population | Ulderich Williams, S. C. Qaddoumi, A. I. Meghreblian, J. T. McBride, M. E. King, S. A. Elahi, M. A. Tuggle, D. Heidel, R. E. Smith, L. M. | Am Surg | 2024 |
Glasgow Coma Score |
| Opioid use and subsequent delirium risk in patients with advanced cancer in palliative care: a multicenter registry study | Yoo, S. H. Kang, J. Kim, H. J. Lee, S. W. Hong, M. Jung, E. H. Kim, Y. J. Yon, D. K. Kang, B. | Sci Rep | 2024 |
Humans |
| Point prevalence and clinical profile of patients with delirium admitted in internal medicine department at tertiary care centre in eastern Nepal: a descriptive cross-sectional study | Yogi, T. N. Puri, S. Shah, B. Nepal, S. Mishra, A. | Ann Med Surg (Lond) | 2024 |
alcoholism |
| Reducing the use of psychotropics in a convalescent rehabilitation ward | Uematsu, T. Tomita, T. Obara, R. Gonai, T. Hattori, K. Aonuma, T. Usui, K. Tanifuji, H. Ishizawa, F. Ishii, H. Suzuki, E. | Neuropsychopharmacol Rep | 2024 |
Humans |
| The impact of postoperative agitated delirium on dementia in surgical patients | Sun, M. Chen, W. M. Wu, S. Y. Zhang, J. | Brain Commun | 2024 |
Psm |
| The impact of postoperative agitated delirium on dementia in surgical patients | Sun, M. Chen, W. M. Wu, S. Y. Zhang, J. | Brain Commun | 2024 |
Psm |
| Effects of human herpesvirus 6B reactivation on cognitive function in cord blood transplant recipients: a prospective multicenter study | Ogata, M. Oshima, K. Takano, K. Kawano, R. Ueda, Y. Imamura, T. Nakamura, Y. Okada, T. Toubai, T. Ueki, T. Uoshima, N. Ishida, H. Shinohara, A. Seo, S. Fukuda, T. Inagaki, M. | Int J Hematol | 2024 |
Humans |
| Modification in ICU Design May Affect Delirium and Circadian Melatonin: A Proof of Concept Pilot Study | Spies, C. Piazena, H. Deja, M. Wernecke, K. D. Willemeit, T. Luetz, A. | Crit Care Med | 2024 |
Adult |
| The effect of nonpharmacological interventions applied by nurses to intensive care patients on the duration of delirium: a meta-analysis study | Söylemez, G. K. Uzun, S. | Ir J Med Sci | 2024 |
Humans |
| Prevalence, risk factors and impact of delirium in adult inpatients in a tertiary care hospital: A point prevalence study | Schiess, C. Hofer, L. Von Felten, S. Bartussek, J. Petry, H. Ernst, J. | J Clin Nurs | 2024 |
cross-sectional studies |
| The association between cerebral blood flow variations during on-pump coronary artery bypass grafting surgery and postoperative delirium | Sampaolesi, C. Casarotta, E. Gresti, G. Mariotti, G. Pisani, L. Veccia, D. Di Eusanio, M. Malvindi, P. G. Donati, A. Münch, C. M. | Perfusion | 2024 |
cerebral blood flow |
| Correlation of Sedation Depth During Critical Care Transport and Hospitalization | Roginski, M. A. Carroll, M. C. Trautwein, M. L. Watkins, E. D. Esteves, A. M. | J Intensive Care Med | 2024 |
Adult |
| The Health Outcomes of a Telegeriatrics Follow-Up Model on Dementia Patients and Their Caregivers in Cairo | Mossad, N. A. Hamza, S. A. Wahba, H. M. F. Youssif, H. Y. Tolba, M. F. | Telemed J E Health | 2024 |
caregiver satisfaction |
| Protect the neck: Devastating outcomes of cervical spine fractures in the elderly | Mormol, J. Krech, L. Pounders, S. Fisk, C. Chapman, A. Karek, M. Hing, K. K. | Am J Surg | 2024 |
Aged |
| Prevalence of clinical electroencephalography findings in stroke patients with delirium | Mintz, N. B. Andrews, N. Pan, K. Bessette, E. Asaad, W. F. Sherif, M. Rubinos, C. Mahta, A. Girard, T. D. Reznik, M. E. | Clin Neurophysiol | 2024 |
Delirium |
| Insulin resistance and osteocalcin associate with the incidence and severity of postoperative delirium in elderly patients undergoing joint replacement | Mi, Y. Wen, O. Lei, Z. Ge, L. Xing, L. Xi, H. | Geriatr Gerontol Int | 2024 |
elderly patients |
| Single-channel qEEG characteristics distinguish delirium from no delirium, but not postoperative from non-postoperative delirium | Lodema, D. Y. Ditzel, F. L. Hut, S. C. A. van Dellen, E. Otte, W. M. Slooter, A. J. C. | Clin Neurophysiol |
Acute encephalopathy |
|
| A Mendelian randomization-based study of the causal relationship between leisure sedentary behavior and delirium | Liu, C. Lv, X. Meng, L. Li, J. Cao, G. | J Affect Disord | 2024 |
Causal relationship |
| Understanding family carer experiences and perceptions of engagement in delirium prevention and care for adults in hospital: Qualitative systematic review | Lee-Steere, K. Mudge, A. Liddle, J. Bennett, S. | J Clin Nurs | 2024 |
Adult |
| The use of the DOS and Delirium Prevalence: a quantitative longitudinal study at a Swiss-German central hospital | Lauffer-Vogt, S. U. Hediger, H. Lauener, S. K. Schubert, M. | Pflege | 2024 |
Female |
| Melatonin does not reduce delirium severity in hospitalized older adults: Results of a randomized placebo-controlled trial | Lange, P. W. Turbić, A. Soh, C. H. Clayton-Chubb, D. Lim, W. K. Conyers, R. Watson, R. Maier, A. B. | J Am Geriatr Soc | 2024 |
aged neurocognitive disorders |
| Immunological Analysis of Postoperative Delirium after Thoracic Aortic Surgery | Ko, H. Kayumov, M. Lee, K. S. Oh, S. G. Na, K. J. Jeong, I. S. | J Chest Surg | 2024 |
Aorta |
| Risk Factors for Postoperative Cognitive Decline After Orthopedic Surgery in Elderly Chinese Patients: A Retrospective Cohort Study | Li, X. Lai, H. Wang, P. Feng, S. Feng, X. Kong, C. Wu, D. Yin, C. Shen, J. Yan, S. Han, R. Liu, J. Ren, X. Li, Y. Tang, L. Xue, D. Zhao, Y. Huang, H. Li, X. Zhang, Y. Wang, X. Wang, C. Jin, P. Lu, S. Wang, T. Zhao, G. Wang, C. | Clin Interv Aging | 2024 |
Aged |
| Clinical Impact of the Implementation Strategies Used to Apply the 2013 Pain, Agitation/Sedation, Delirium or 2018 Pain, Agitation/Sedation, Delirium, Immobility, Sleep Disruption Guideline Recommendations: A Systematic Review and Meta-Analysis | Hume, N. E. Zerfas, I. Wong, A. Klein-Fedyshin, M. Smithburger, P. L. Buckley, M. S. Devlin, J. W. Kane-Gill, S. L. | Crit Care Med | 2024 |
Adult |
| Delirium and incident dementia in hospital patients in New South Wales, Australia: retrospective cohort study | Gordon, E. H. Ward, D. D. Xiong, H. Berkovsky, S. Hubbard, R. E. | Bmj | 2024 |
Male |
| Effect of subanesthetic dose of esketamine on postoperative pain in elderly patients undergoing laparoscopic gastrointestinal tumor Surgery:A prospective, double-blind, randomized controlled trial | Jing, Z. Han, Y. Li, Y. Zeng, R. Wu, J. Wang, Y. Jiang, P. | Heliyon | 2024 |
Analgesia |
| Predictive Ability of Amplitude Integrated Electroencephalography for Adverse Outcomes in Neonates with Sepsis-Associated Encephalopathy: A Cohort Study | Jain, P. Saini, S. S. Sahu, J. K. Madaan, P. Sundaram, V. Dutta, S. | Indian J Pediatr | 2024 |
Cerebral function monitor |
| Perioperative knowledge, self-efficacy and clinical practices related to postoperative delirium care in older people across geographical regions in Australia | Igwe, E. O. Nealon, J. O'Shaughnessy, P. Ormonde, C. Traynor, V. | Aust J Rural Health | 2024 |
Australia |
| A survey of non-consultant hospital doctors' perspectives, knowledge, and practices toward delirium in a large Irish hospital | Hassabo, M. Mc Cluskey, P. Browne, J. Ntlholang, O. | Ir J Med Sci | 2024 |
4at |
| Dynamic delirium - Nursing intervention to reduce delirium in patients critically Ill, a randomized control trial | Gómez Tovar, L. O. Henao Castaño, A. M. | Intensive Crit Care Nurs | 2024 |
Clinical Trial |
| Delirium is more common and associated with worse outcomes in Parkinson's disease compared to older adult controls: results of two prospective longitudinal cohort studies | Gerakios, F. Yarnall, A. J. Bate, G. Wright, L. Davis, D. Stephan, B. C. M. Robinson, L. Brayne, C. Stebbins, G. Taylor, J. P. Burn, D. J. Allan, L. M. Richardson, S. J. Lawson, R. A. | Age Ageing | 2024 |
Humans |
| Effectiveness of remimazolam in preventing postoperative delirium in elderly patients with proximal femoral fractures | Fujimoto, D. Obata, N. Mizobuchi, S. | J Anesth | 2024 |
Elderly |
| Association between body mass index and delirium incidence in critically ill patients: a retrospective cohort study based on the MIMIC-IV Database | Fu, J. Zhang, X. Zhang, G. Wei, C. Fu, Q. Gui, X. Ji, Y. Chen, S. | BMJ Open | 2024 |
Humans |
| Structural disconnectivity in postoperative delirium: A perioperative two-center cohort study in older patients | Fislage, M. Winzeck, S. Woodrow, R. Lammers-Lietz, F. Stamatakis, E. A. Correia, M. M. Preller, J. Feinkohl, I. Hendrikse, J. Pischon, T. Spies, C. D. Slooter, A. J. C. Winterer, G. Menon, D. K. Zacharias, N. | Alzheimers Dement | 2024 |
brain health |
| Effects of short-term preoperative intranasal dexmedetomidine plus conventional treatment on delirium following cardiac surgery in patients with sleep disorders | Fang, J. Yang, J. Zhai, M. Zhang, Q. Zhang, M. Xie, Y. | Perioper Med (Lond) | 2024 |
Cognitive function |
| The predictive value of confusion assessment method-intensive care unit and intensive care delirium screening checklist for delirium in critically ill patients in the intensive care unit: A systematic review and meta-analysis | Diao, Y. Yu, X. Zhang, Q. Chen, X. | Nurs Crit Care | 2024 |
Cam‐icu |
| Factors associated with disagreement between clinician app-based ultra-brief Confusion Assessment Method and reference standard delirium assessments | Dhliwayo, R. Trivedi, S. Ngo, L. Fick, D. M. Inouye, S. K. Boltz, M. Leslie, D. Husser, E. Shrestha, P. Marcantonio, E. R. | J Am Geriatr Soc | 2024 |
Humans |
| Cognitive disorders in advanced Parkinson's disease: challenges in the diagnosis of delirium | Daniels, C. Rodríguez-Antigüedad, J. Jentschke, E. Kulisevsky, J. Volkmann, J. | Neurol Res Pract | 2024 |
Cognition |
| Assessment and management of delirium in a tertiary hospital-Improvements in cognitive screening and use of non-pharmacological strategies with a multidisciplinary approach | Clarke, E. Newman, E. Dravid, M. Ricciardello, M. Jones, E. Caudle, K. Kilshaw, L. Hilmi, S. Flicker, L. | Australas J Ageing | 2024 |
Humans |
| Assessment of level of knowledge, attitude, and associated factors toward delirium among health professionals working in intensive care unit multicenter, cross-sectional study, Amhara region comprehensive specialized hospitals, Northwest Ethiopia, 2023 | Ayanaw Eyayu, R. Gudayu Zeleke, T. Chekol, W. B. Yaregal Melesse, D. Enyew Ashagrie, H. | Front Public Health | 2024 |
Humans |
| The evaluation of frequency and predictors of delirium and its short-term and long-term outcomes in hospitalized older adults' | Ajmera, Y. Paul, K. Khan, M. A. Kumari, B. Kumar, N. Chatterjee, P. Dey, A. B. Chakrawarty, A. | Asian J Psychiatr | 2024 |
Humans |
| The impact of ketamine on outcomes in critically ill patients: a systematic review with meta-analysis and trial sequential analysis of randomized controlled trials | Abdildin, Y. Tapinova, K. Nemerenova, A. Viderman, D. | Acute Crit Care | 2024 |
critical care |
| Spanish transcultural adaptation of the 4AT score for the evaluation of delirium in the emergency department: a prospective diagnostic test accuracy study | Morales-Puerto, M. Ruiz-Díaz, M. García-Mayor, S. León-Campos, Á Morales-Asencio, J. M. Canca-Sánchez, J. C. Gavira-Guerra, S. Toledo-Fernandez, C. Aranda-Gallardo, M. | BMC Nurs | 2024 |
4at |
| Face and content validity of a mobile delirium screening tool adapted for use in the medical setting (eDIS-MED): Welcome to the machine | Eeles, E. Tronstad, O. Teodorczuk, A. Flaws, D. Fraser, J. F. Dissanayaka, N. | Australas J Ageing | 2924 |
computerized adaptive testing |
| Social determinants of health and incident postoperative delirium: Exploring key relationships in the SAGES study | Arias, F. Dufour, A. B. Jones, R. N. Alegria, M. Fong, T. G. Inouye, S. K. | J Am Geriatr Soc | 2024 |
Humans |
| Combining biomarkers of BNIP3 L, S100B, NSE and accessible measures to prediction sepsis-associated encephalopathy: a prospective observational study | Zhang, N. Xie, K. Yang, F. Wang, Y. Yang, X. Zhao, L. | Curr Med Res Opin | 2024 |
Bnip3 l |
| Association between preoperative albumin levels and postoperative delirium in geriatric hip fracture patients | Wang, W. Yao, W. Tang, W. Li, Y. Lv, Q. Ding, W. | Front Med (Lausanne) | 2024 |
Pod |
| Antipsychotic Use for ICU Delirium and Associated Inflammatory Markers | Torbic, H. Chen, A. Lumpkin, M. Yerke, J. Mehkri, O. Abraham, S. Wang, X. Duggal, A. Scheraga, R. G. | J Intensive Care Med | 2024 |
Adult |
| Delirium is frequently underdiagnosed among older hospitalised patients despite available information in hospital medical records | Titlestad, I. Haugarvoll, K. Solvang, S. H. Norekvål, T. M. Skogseth, R. E. Andreassen, O. A. Årsland, D. Neerland, B. E. Nordrehaug, J. E. Tell, G. S. Giil, L. M. | Age Ageing | 2024 |
Humans |
| Factors associated with delirium in a real-world acute-care setting: analysis considering the interdependence of clinical variables with the frailty syndrome | Ticinesi, A. Parise, A. Delmonte, D. Coppi, C. Prati, B. Cerundolo, N. Guerra, A. Nouvenne, A. Meschi, T. | Eur Geriatr Med | 2024 |
Acute cerebral dysfunction |
| Increased IgA-mediated responses to the gut paracellular pathway and blood-brain barrier proteins predict delirium due to hip fracture in older adults | Thisayakorn, P. Thipakorn, Y. Tantavisut, S. Sirivichayakul, S. Vojdani, A. Maes, M. | Front Neurol | 2024 |
bacterial translocation |
| Association of peripheral B cells and delirium: combined single-cell sequencing and Mendelian randomization analysis | Tan, S. Pan, S. Wei, L. Chen, W. Pan, B. Kong, G. Chen, J. Xie, Y. | Front Neurol | 2024 |
B cell |
| Clinical Outcomes after Multivalve Surgery in Octogenarians: Evaluating the Need for a Paradigm Shift | Taghizadeh-Waghefi, A. Petrov, A. Arzt, S. Alexiou, K. Tugtekin, S. M. Matschke, K. Kappert, U. Wilbring, M. | J Clin Med | 2024 |
multivalve disease |
| Evaluating early lymphocyte-to-monocyte ratio as a predictive biomarker for delirium in older adult patients with sepsis: insights from a retrospective cohort analysis | Shi, X. Yang, L. Bai, W. Jing, L. Qin, L. | Front Med (Lausanne) | 2024 |
Mimic-iv |
| The Association of Preoperative Diabetes With Postoperative Delirium in Older Patients Undergoing Major Orthopedic Surgery: A Prospective Matched Cohort Study | Shang, Z. Jiang, Y. Fang, P. Zhu, W. Guo, J. Li, L. Liang, Y. Zhang, S. Ma, S. Mei, B. Fan, Y. Xie, Z. Shen, Q. Liu, X. | Anesth Analg | 2024 |
Postoperative delirium diabetes orthopedic surgery elective surgery 3D-CAM delirium severity
|
| The role of neurohospitalism in a specialized cardiovascular hospital | Serôdio, M. Magriço, M. Sobral-Pinho, A. Ventura, R. Serrazina, F. Cabral, G. Meira, B. Fernandes, M. Salavisa, M. Saraiva, M. Marto, J. P. Sá, F. Calado, S. Baptista, M. V. | Eur Neurol | 2024 |
Cardiovascular neurology delirium altered mental status AIS
|
| Bringing Delirium to Light: Impact of CAM-ICU Tool to Improve Care Coordination | Savino, T. Vergara, F. H. Ramos, M. D. Warzecha, D. | Prof Case Manag | 2024 |
Delirium CCU Early assessment CAM-ICU Length of Stay Case Management |
| Delirium and Its Associations with Critical Care Utilizations and Outcomes at the Time of Hospital Discharge in Patients with Acute Brain Injury | Raquer, A. P. Fong, C. T. Walters, A. M. Souter, M. J. Lele, A. V. | Medicina (Kaunas) | 2024 |
Humans |
| Data-derived subtypes of delirium during critical illness | Potter, K. M. Kennedy, J. N. Onyemekwu, C. Prendergast, N. T. Pandharipande, P. P. Ely, E. W. Seymour, C. Girard, T. D. | EBioMedicine | 2024 |
Adult |
| Infection, delirium, and risk of dementia in patients with and without white matter disease on previous brain imaging: a population-based study | Pendlebury, S. T. Luengo-Fernandez, R. Seeley, A. Downer, M. B. McColl, A. Rothwell, P. M. | Lancet Healthy Longev | 2024 |
United States |
| A novel risk assessment tool for postoperative delirium in vascular surgery: The stress model (Siena posTopeRative dElirium in vaScular Surgery) | Pasqui, E. de Donato, G. Brancaccio, B. Casilli, G. Ferrante, G. Palasciano, G. | Vascular | 2024 |
Vascular surgery |
| The Delphi Delirium Management Algorithms. A practical tool for clinicians, the result of a modified Delphi expert consensus approach | Ottens, T. H. Hermes, C. Page, V. Oldham, M. Arora, R. Bienvenu, O. J., 3rd van den Boogaard, M. Caplan, G. Devlin, J. W. Friedrich, M. E. van Gool, W. A. Hanison, J. Hansen, H. C. Inouye, S. K. Kamholz, B. Kotfis, K. Maas, M. B. MacLullich, A. M. J. Marc | Delirium (Bielef) | 2024 |
Clinical practice algorithm |
| Identification of early delirium and its outcomes after cardiopulmonary bypass among adult patients with cardiovascular disease: a prospective observational study | Othman, S. M. A. Xu, Q. Zhao, K. Kafi, L. Aziz, M. A. A. | Indian J Thorac Cardiovasc Surg | 2024 |
Bypass machine |
| Association between Preoperative Glucose Dysregulation and Delirium after Non-Cardiac Surgery | Oh, A. R. Lee, D. Y. Lee, S. Lee, J. H. Yang, K. Choi, B. Park, J. | J Clin Med | 2024 |
delirium |
| Epidural vs. systemic analgesia in the Intensive Care Unit: retrospective study of patient outcomes | Naser, A. Meyer, A. Ifrach, N. Dichtwald, S. | Minerva Anestesiol | 2024 |
Humans |
| Whole blood thiamine, intravenous thiamine supplementation and delirium occurrence in the intensive care unit: retrospective cohort analyses | Mumin, M. A. McKenzie, C. A. Page, V. J. Hadfield, D. Aitken, L. M. Hanks, F. Cunningham, E. Blackwood, B. Van Dellen, E. Slooter, A. J. C. Grocott, M. P. W. McAuley, D. F. Spronk, P. E. | Int J Clin Pharm | 2024 |
Critical care |
| Intraoperative Blood Pressure Management and Its Effects on Postoperative Delirium After Cardiac Surgery: A Single-Center Retrospective Cohort Study | Mohr, N. L. Krannich, A. Jung, H. Hulde, N. von Dossow, V. | J Cardiothorac Vasc Anesth | 2024 |
Ioh |
| Implementing pain, agitation, delirium, and sleep deprivation protocol in critically ill patients: A pilot study on pharmacological interventions | Luetrakool, P. Taesotikul, S. Susantitapong, K. Suthisisang, C. Morakul, S. Sutherasan, Y. Tangsujaritvijit, V. Dilokpattanamongkol, P. | Clin Transl Sci | 2024 |
Humans |
| An exploratory research report on brain mineralization in postoperative delirium and cognitive decline | Lammers-Lietz, F. Borchers, F. Feinkohl, I. Hetzer, S. Kanar, C. Konietschke, F. Lachmann, G. Chien, C. Spies, C. Winterer, G. Zaborszky, L. Zacharias, N. Paul, F. | Eur J Neurosci | 2024 |
anaesthesia |
| Delirium Severity and Physical Function in Hospitalized Persons Living With Dementia: Moderation by Age, Sex, and Race | Kuzmik, A. Boltz, M. Resnick, B. McPherson, R. Rodriguez, M. Drazich, B. F. Galik, E. | Alzheimer Dis Assoc Disord | 2024 |
Male |
| Effectiveness of antipsychotics for managing agitated delirium in patients with advanced cancer: a secondary analysis of a multicenter prospective observational study in Japan (Phase-R) | Kurisu, K. Inada, S. Maeda, I. Nobata, H. Ogawa, A. Iwase, S. Uchida, M. Akechi, T. Amano, K. Nakajima, N. Morita, T. Sumitani, M. Yoshiuchi, K. | Support Care Cancer | 2024 |
Humans |
| The spectrum of psychological disorders in family members of patients suffering from delirium associated with critical illness: a prospective, observational study | Kotfis, K. Maj, P. Szylińska, A. Pankowiak, M. Reszka, E. Ely, E. W. Marra, A. | Sci Rep | 2024 |
Adult |
| Impact of Prefracture Cognitive Impairment and Postoperative Delirium on Recovery After Hip Fracture Surgery | Kamimura, T. Kobayashi, Y. Tamaki, S. Koinuma, M. | J Am Med Dir Assoc | 2024 |
Cognitive impairment |
| Development of a Prediction Model for Delirium in Hospitalized Patients with Advanced Cancer | Jung, E. H. Yoo, S. H. Lee, S. W. Kang, B. Kim, Y. J. | Cancer Res Treat | 2024 |
Delirium |
| Nurses' Knowledge and Subjective Strain in Delirium Care: Impact of a Web-based Instructional Module on Nurses Competence | Jose, S. Cyriac, M. C. Dhandapani, M. | Indian J Crit Care Med | 2024 |
Delirium |
| Difficulties faced by intensive care nurses in caring for patients with delirium: A cross-sectional, multicentre study | Jiang, T. Tung, T. H. Wang, Y. Zheng, X. T. Jia, L. Zhang, W. | Aust Crit Care | 2024 |
Cross-sectional study |