What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Safety and Tolerability of Rapid Administration Undiluted Levetiracetam
- Authors
- Morgan, O. Medenwald, B.
- Year
- 2020
- Journal
- Neurocrit Care
- Abstract
BACKGROUND/OBJECTIVE: Levetiracetam (LEV) is an antiepileptic drug used widely in patients with a favorable safety profile. Studies evaluating the safety and efficacy of intravenous (IV) LEV included volumes of at least 100 mL. Minimally diluted doses administered over 5-6 min were found to be both safe and effective. Given the complexities of admixing, this practice can be impractical and result in delays in antiepileptic therapy. This study aimed to retrospectively review the safety and tolerability of rapid administration of undiluted LEV doses </= 1000 mg. METHODS: This was a retrospective study evaluating adverse drug reactions associated with undiluted LEV from January 1, 2018-June 1, 2018. Patients were included if they received at least one dose of undiluted LEV and were >/= 18 years old. Safety endpoints were reviewed and collected from the time administration until hospital discharge. Endpoints included injection site pain and discomfort, injection site erythema, extravasation, IV line replacement, and any documented adverse effect leading to IV LEV discontinuation. Descriptive statistics were used to analyze the data. RESULTS: A total of 199 patients were included in the study totaling 1626 doses of LEV. Most patients were administered LEV 1000 mg (60.8%), through a peripheral line (64.3%), and were prescribed LEV for seizure prophylaxis (58.3%). Patients received a mean of 8.1 +/- 8 doses for a mean duration of therapy of 5 +/- 4.5 days. About 98.5% of patients did not experience an adverse effect, whereas 1.5% of patients experienced agitation, delirium, confusion, and/or lethargy, which is well known to LEV therapy. CONCLUSIONS: Rapid administration of undiluted LEV doses </= 1000 mg were well tolerated with no concentration-related side effects. Further prospective research is needed to confirm this observation as well as the safety of higher doses.
- PMID
- Keywords
Anticonvulsants
Humans
Intravenous
- Page(s)
- 131-134
- Volume
- 32
- Issue
- 1
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Accuracy of Delirium Screening Tools in Older People with Cancer-A Systematic Review | Martínez-Arnau, F. M. Puchades-García, A. Pérez-Ros, P. | Cancers (Basel) | 2023 |
accuracy, aged, assessment, cancer, delirium, incidence, prevalence, psychometric properties |
| Evaluation of the delirium preventive effect of dual orexin receptor antagonist (DORA) in critically ill adult patients requiring ventilation with tracheal intubation at an advanced emergency center: A single-center, retrospective, observational study | Matsuoka, A. Sogawa, R. Murakawa-Hirachi, T. Mizoguchi, Y. Monji, A. Shimanoe, C. Shinada, K. Koami, H. Sakamoto, Y. | J Alzheimers Dis | 2023 |
Humans, Adult, Adolescent, *Orexin Receptor Antagonists/adverse effects, Retrospective Studies, Critical Illness/therapy, *Delirium/prevention & control/epidemiology, Intubation, Intratracheal, Delirium, Intensive care unit, Lemborexant, Sleep disorder, Suvorexant |
| Individualized Summary Assessment of Detailed Neuropsychological Testing for the Etiological Diagnosis of Newly Detected Cognitive Impairment in Hospitalized Geriatric Patients | Mäurer, A. Himmel, G. Lange, C. Mathies, F. Apostolova, I. Peters, O. Buchert, R. | J Alzheimers Dis | 2023 |
Alzheimer’s disease, delirium, dementia, etiological diagnosis, hospitalized, geriatric patients, neuropsychological testing |
| A systematic review of studies reporting on neuropsychological and functional domains used for assessment of recovery from delirium in acute hospital patients | McCartney, H. Noble, E. MacLullich, A. M. J. Davis, D. H. J. Evans, J. Shenkin, S. D. Muniz-Terrera, G. Sandeman, D. Tieges, Z. | Int J Geriatr Psychiatry | 2023 |
Humans, *Activities of Daily Living, *Delirium/diagnosis/drug therapy |
| Implementing a ward-based programme to improve care for older inpatients: process evaluation of the cluster randomised CHERISH trial | Mudge, A. M. McRae, P. Young, A. Blackberry, I. Lee-Steere, K. Barrimore, S. Quirke, T. Harvey, G. | BMC Health Serv Res | 2023 |
Aged, Humans, *Delirium/prevention & control, Hospitals, *Inpatients, Nutritional Status, Prospective Studies, Age-friendly hospitals, Delirium, Evaluation, Facilitation, Implementation |
| Effect of laparoscopic liver resection on postoperative delirium in elderly patients with hepatocellular carcinoma | Nomi, T. Kaibori, M. Hirokawa, F. Ueno, M. Hokuto, D. Noda, T. Nakai, T. Ikoma, H. Iida, H. Kubo, S. | J Hepatobiliary Pancreat Sci | 2023 |
elderly patients, hepatocellular carcinoma, laparoscopic liver resection, postoperative delirium |
| Development of a scale measuring the difficulties faced by nurses who care for patients with delirium in intensive care units | Owaki, N. Tanaka, M. Kawakami, A. | Aust Crit Care | 2023 |
Humans, Reproducibility of Results, Pilot Projects, Intensive Care Units, Surveys and Questionnaires, *Delirium, *Nurses, Psychometrics/methods, Delirium, Exploratory factor analysis, Nurse, Psychological distress, Scale development |
| Preliminary evaluation of a smartphone application (DelApp) for identification of delirium in sub-Saharan Africa | Paddick, S. M. Gamassa, E. Mwaluwinga, N. Lewis, G. Duinmaijer, A. Urasa, S. Tucker, L. Mukaetova-Ladinska, E. B. Cosker, G. Dekker, M. Kisoli, A. Cletus, J. Lissu, C. Dotchin, C. Gray, W. K. Walker, R. | Acta Neuropsychiatr | 2023 |
Africa, cognitive assessment, delirium, screening |
| Postoperative delirium after cholecystectomy in older patients: A retrospective study | Park, Y. M. Seo, H. I. Noh, B. G. Kim, S. Hong, S. B. Lee, N. K. Kim, D. U. Han, S. Y. | Ann Hepatobiliary Pancreat Surg | 2023 |
Body mass index, Cholecystectomy, Delirium, Nutrition, Older patients |
| Exploring the Documentation of Delirium in Patients After Cardiac Surgery: A Retrospective Patient Record Study | Poikajärvi, S. Peltonen, L. M. Siirala, E. Heimonen, J. Moen, H. Salanterä, S. Junttila, K. | Comput Inform Nurs | 2023 |
delirium, cardiac, surgery, EHR, documentation |
| The Efficacy of Low-Dose Risperidone Treatment for Post-Surgical Delirium in Elderly Orthopedic Patients | Raphael, L. Edna, E. Irina, K. Oded, H. | Medicina (Kaunas) | 2023 |
Female, Humans, Aged, Aged, 80 and over, Male, Risperidone/adverse effects, Prospective Studies, *Delirium/drug therapy/etiology/diagnosis, *Orthopedics, Postoperative Complications/drug therapy, delirium, elderly, post-surgical, protocol, risperidone |
| Serum Biomarkers of a Pro-Neuroinflammatory State May Define the Pre-Operative Risk for Postoperative Delirium in Spine Surgery | Ruhnau, J. Müller, J. Nowak, S. Strack, S. Sperlich, D. Pohl, A. Dilz, J. Saar, A. Veser, Y. Behr, F. Rehberg, S. Usichenko, T. Hahnenkamp, K. Ehler, J. Flöel, A. Schroeder, H. W. S. Müller, J. U. Fleischmann, R. Vogelgesang, A. | Int J Mol Sci | 2023 |
Humans, Aged, *Emergence Delirium, Interleukin-6/metabolism, *Delirium/diagnosis/etiology, Gasdermins, Postoperative, Complications/etiology, Prospective Studies, Biomarkers/metabolism, Gasdermin D, biomarker, postoperative cognitive dysfunction, postoperative delirium, sTREM2, spine surgery |
| Effects of an interactive handgrip game on surgical patients requiring intensive care: An assessor-blinded randomized controlled trial | Han, P. H. Shih, C. Y. Wang, A. Y. Chen, Y. C. Yang, C. C. Fan, Y. C. Hsiang, H. F. Chiu, H. Y. | Intensive Crit Care Nurs | 2023 |
Critically ill patients, Handgrip strength, Interactive handgrip game, Psychological distress |
| A critical appraisal and recommendation synthesis of delirium clinical practice guidelines relevant to the care of older adults in the emergency department: An umbrella review | Filiatreault, S. Grimshaw, J. M. Kreindler, S. A. Chochinov, A. Linton, J. Chatterjee, R. Azeez, R. Doupe, M. B. | J Eval Clin Pract | 2023 |
Agree, aged, delirium, emergency services (hospital), practice guideline, systematic review |
| Implementation of a novel nursing assessment tool in geriatric trauma patients with proximal femur fractures | Berk, T. Thalmann, M. Jensen, K. O. Schwarzenberg, P. Jukema, G. N. Pape, H. C. Halvachizadeh, S. | PLoS One | 2023 |
Humans, Aged, Retrospective Studies, *Proximal Femoral Fractures, *Delirium/etiology/complications, Risk Factors, Nutritional Status, Geriatric Assessment |
| Enhanced recovery after surgery in patients with normal pressure hydrocephalus undergoing ventriculoperitoneal shunting procedures | Ali, A. Gupta, B. Johansen, P. Santiago, R. B. Dabecco, R. Mandel, M. Adada, B. Botero, J. Roy, M. Borghei-Razavi, H. | Clin Neurol Neurosurg | 2023 |
Humans, Ventriculoperitoneal Shunt/adverse effects, *Hydrocephalus, Normal Pressure/surgery/complications, *Enhanced Recovery After Surgery, Postoperative Complications/etiology, *Delirium/complications/surgery, Length of Stay, Retrospective Studies, Delirium, Eras, Neurosurgery, Normal pressure hydrocephalus, Ventriculoperitoneal shunting |
| The use of patient sitters at a Swiss hospital: A retrospective observational study | Kramer, I. Schubert, M. | PLoS One | 2023 |
Aged, Humans, Confusion, *Ethnicity, Hospitals, *Inpatients, Retrospective Studies, Switzerland, Aged, 80 and over |
| The role of inflammatory parameters in the prediction of postoperative delirium in patients undergoing coronary artery bypass grafting | Şaşkin, H. Özcan, K. S. Yildirim, S. | Cardiovasc J Afr | 2023 |
Humans, *Emergence Delirium/etiology, Retrospective Studies, Postoperative Complications/diagnosis/etiology, Coronary Artery Bypass/adverse effects, Risk Factors, coronary artery bypass grafting surgery, delirium, inflammation |
| Opioids increase the risk of delirium in critically ill patients: A propensity score analysis | Shi, H. J. Zhang, X. P. Hai, C. Shi, W. Wang, P. Hu, A. M. | Int J Clin Pharmacol Ther | 2023 |
Humans, *Analgesics, Opioid/adverse effects, Intensive Care Units, Critical, Illness/therapy, Propensity Score, Risk Factors, *Delirium/chemically induced/diagnosis/epidemiology |
| Characteristics of delirium and its association with sedation and in-hospital mortality in patients with COVID-19 on veno-venous extracorporeal membrane oxygenation | Sun, P. Y. Fanning, J. Peeler, A. Shou, B. Lindsley, J. Caturegli, G. Whitman, G. Cha, S. Kim, B. S. Cho, S. M. | Front Med (Lausanne) | 2023 |
analgesia, deep sedation, delirium, extracorporeal membrane oxygenation, hospital mortality |
| Delirium as a Risk Factor for Mortality in Critically Ill Patients With Cancer | Tao, J. Seier, K. Marasigan-Stone, C. B. Simondac, J. S. Pascual, A. V. Kostelecky, N. T. SantaTeresa, E. Nwogugu, S. O. Yang, J. J. Schmeltz, J. Tan, K. S. Chawla, S. Voigt, L. P. | JCO Oncol Pract | 2023 |
Humans, Female, Middle Aged, Aged, Male, *Delirium/diagnosis/prevention & control, Critical Illness, Risk Factors, Intensive Care Units, *Neoplasms |
| Effectiveness of sleep interventions to reduce delirium in critically ill patients: A systematic review and meta-analysis | Teng, J. Qin, H. Guo, W. Liu, J. Sun, J. Zhang, Z. | J Crit Care | 2023 |
Critical illness, Delirium, ICUs, Meta-analysis, Sleep |
| Chlorpromazine's Potential Role in Palliating Distressing Symptoms Associated With Hyperactive Delirium in Patients at End of Life | Tiefenthaler, C. M. Hirst, J. M. Edmonds, K. P. Atayee, R. S. | J Palliat Med | 2023 |
Humans, Chlorpromazine/therapeutic use, Psychomotor Agitation/drug therapy/complications/prevention & control, *Delirium/drug therapy, *Neoplasms/complications, Death, Palliative Care, chlorpromazine |
| Delirium and IL-6 added to clinical scores improves their performance: a prospective analysis of CALL, PREDI-CO, MRS score applied to a population of patients admitted to internal medicine ward | Vannucchi, V. Pelagatti, L. Barone, F. Bertini, L. Celli, T. Boccia, N. Veneziani, F. Cimolato, B. Landini, G. | Intern Emerg Med | 2023 |
Call, Covid-19, Delirium,il-6, Mrs, Outcome, Predi-co, Score |
| Electroencephalographic Biomarkers, Cerebral Oximetry, and Postoperative Cognitive Function in Adult Non-Cardiac Surgical Patients: a Prospective Cohort Study | Vlisides, P. E. Li, D. Maywood, M. Zierau, M. Lapointe, A. P. Brooks, J. McKinney, A. M. Leis, A. M. Mentz, G. Mashour, G. A. | Anesthesiology | 2023 |
Adult, Humans, Retrospective Studies, Prospective Studies, *Delirium/diagnosis/epidemiology/etiology, Critical Illness, Intensive Care Units, Critically ill, Delirium, Intensive care unit, Machine learning, Prediction |
| Early prediction of delirium upon intensive care unit admission: Model development, validation, and deployment | Wang, M. L. Kuo, Y. T. Kuo, L. C. Liang, H. P. Cheng, Y. W. Yeh, Y. C. Tsai, M. T. Chan, W. S. Chiu, C. T. Chao, A. Chou, N. K. Yeh, Y. C. Ku, S. C. | J Clin Anesth | 2023 |
Adult, Humans, Retrospective Studies, Prospective Studies, *Delirium/diagnosis/epidemiology/etiology, Critical Illness, Intensive Care Units, Critically ill, Delirium, Intensive care unit, Machine learning, Prediction |
| Perioperative cerebral perfusion in aortic arch surgery: a potential link with neurological outcome | Weijs, R. W. J. Tromp, S. C. Heijmen, R. H. Seeber, A. A. van Belle-van Haaren, Njcw Claassen, Jahr Thijssen, D. H. J. | Eur J Cardiothorac Surg | 2023 |
Humans, Aorta, Thoracic/diagnostic imaging/surgery, *Brain Ischemia/etiology/prevention & control, Retrospective Studies, *Stroke/etiology/prevention & control, Perfusion, *Ischemic Stroke, Cerebrovascular Circulation/physiology, *Delirium, Treatment Outcome, Postoperative Complications/prevention & control, *Aortic Aneurysm, Thoracic/surgery, Antegrade selective cerebral perfusion, Aortic surgery, Cerebral circulation, Perioperative management, Postoperative complication, Thoracic aorta |
| Preoperative Cognitive Impairment and Postoperative Delirium in Elderly Surgical Patients: A Retrospective Large Cohort Study (The CIPOD Study) | Weiss, Y. Zac, L. Refaeli, E. Ben-Yishai, S. Zegerman, A. Cohen, B. Matot, I. | Ann Surg | 2023 |
Humans, Aged, *Emergence Delirium/complications, *Delirium/diagnosis/epidemiology/etiology, Retrospective Studies, Cohort Studies, Prospective Studies, *Cognitive Dysfunction/diagnosis/epidemiology, Postoperative Complications/etiology, Risk Factors |
| Contribution of Different Brain Disorders and Multimorbidity to Delirium Superimposed Dementia (DSD) | Wetterling, T. Junghanns, K. | Geriatrics (Basel) | 2023 |
brain infarction, deliriumm dementia, multimorbidity, white matter hyperintensities |
| Prevalence and Risk Factors for Intensive Care Unit Delirium After Traumatic Brain Injury: A Retrospective Cohort Study | Wilson, L. D. Maiga, A. W. Lombardo, S. Nordness, M. F. Haddad, D. N. Rakhit, S. Smith, L. F. Rivera, E. L. Cook, M. R. Thompson, J. L. Raman, R. Patel, M. B. | Neurocrit Care | 2023 |
Adult, Humans, Retrospective Studies, Prevalence, *Brain Injuries,, Traumatic/complications/epidemiology, Risk Factors, Intensive Care Units, *Subarachnoid Hemorrhage/complications, *Delirium/epidemiology/etiology, Glasgow Coma Scale,Critical illness, Delirium, Mental status, Predictors, Traumatic brain injury |
| Moderate-to-high risk of obstructive sleep apnea with excessive daytime sleepiness is associated with postoperative neurocognitive disorders: a prospective one-year follow-up cohort study | Wu, W. Pu, L. Hu, X. Chen, Q. Wang, G. Wang, Y. | Front Neurosci | 2023 |
excessive daytime sleepiness, obstructive sleep apnea, older adults, perioperative neurocognitive disorders, surgery |
| Effect of Dexmedetomidine on Posttraumatic Stress Disorder in Patients Undergoing Emergency Trauma Surgery: A Randomized Clinical Trial | Yu, Y. Li, Y. Han, D. Gong, C. Wang, L. Li, B. Yao, R. Zhu, Y. | JAMA Netw Open | 2023 |
Male, Humans, Adult, *Dexmedetomidine/therapeutic use/adverse effects, *Stress Disorders, Post-Traumatic/epidemiology/prevention & control, Saline Solution, *Emergence Delirium/chemically induced, Administration, Intravenous |
| Regional versus general anesthesia in older patients for hip fracture surgery: a systematic review and meta-analysis of randomized controlled trials | Zhou, S. L. Zhang, S. Y. Si, H. B. Shen, B. | J Orthop Surg Res | 2023 |
Humans, Aged, Randomized Controlled Trials as Topic, *Hip Fractures/surgery, Anesthesia, General/adverse effects, *Plastic Surgery Procedures, *Delirium, Anesthesia, General, Hip fracture, Meta-analysis, Regional |
| Delirium in Medically Hospitalized Patients: Prevalence, Recognition and Risk Factors: A Prospective Cohort Study | Al Farsi, R. S. Al Alawi, A. M. Al Huraizi, A. R. Al-Saadi, T. Al-Hamadani, N. Al Zeedy, K. Al-Maqbali, J. S. | J Clin Med | 2023 |
delirium, elderly, incidence, prevalence, risk factors |
| Delirium detection using wearable sensors and machine learning in patients with intracerebral hemorrhage | Ahmed, A. Garcia-Agundez, A. Petrovic, I. Radaei, F. Fife, J. Zhou, J. Karas, H. Moody, S. Drake, J. Jones, R. N. Eickhoff, C. Reznik, M. E. | Front Neurol | 2023 |
actigraphy, delirium, intracerebral hemorrhage, machine learning, neurocritical care, stroke, wearable electronic devices |
| Associations of postoperative delirium with activities of daily living in older people after major surgery: A prospective cohort study | Aldwikat, R. K. Manias, E. Holmes, A. C. Tomlinson, E. Nicholson, P. | J Clin Nurs | 2023 |
activities of daily living, cognition, older surgical patients, post-anaesthetic care unit, postoperative delirium |
| Association Between Risk of Stroke and Delirium After Cardiac Surgery and a New Electroencephalogram Index of Interhemispheric Similarity | Baron Shahaf, D. Hight, D. Kaiser, H. Shahaf, G. | J Cardiothorac Vasc Anesth | 2023 |
Eeg, Lir, delirium, stroke |
| Melatonin and Ramelteon for the treatment of delirium: A systematic review and meta-analysis | Beaucage-Charron, J. Rinfret, J. Coveney, R. Williamson, D. | J Psychosom Res | 2023 |
Humans, Aged, *Melatonin/therapeutic use, *Delirium/drug therapy, *Indenes/therapeutic use, *Antipsychotic Agents/therapeutic use, Delirium, Melatonergic agonist, Melatonin, Ramelteon, Treatment |
| A Core Outcome Set for Interventions to Prevent and/or Treat Delirium in Palliative Care | Bryans, A. Siddiqi, N. Burry, L. Clarke, M. Koffman, J. Agar, M. R. Rose, L. | J Pain Symptom Manage | 2023 |
Delirium, clinical trials, core outcome set, palliative care |
| Delirium in the Era of COVID-19 | Byrnes, T. Pate, K. Cochran, A. R. Belin, L. | J Nurs Care Qual | 2023 |
delirium, covid-19, older adults, |
| Leveraging the Electronic Health Record to Implement Emergency Department Delirium Screening | Chary, A. N. Brickhouse, E. Torres, B. Santangelo, I. Carpenter, C. R. Liu, S. W. Godwin, K. M. Naik, A. D. Singh, H. Kennedy, M. | Appl Clin Inform | 2023 |
Humans, Aged, *Electronic Health Records, Emergency Service, Hospital, Attitude of Health Personnel, *Delirium/diagnosis |
| Cigarette smoking is linked to an increased risk of delirium following arthroplasty in patients suffering from osteoarthritic pain | Chen, J. R. Chen, J. Q. Hu, J. C. Huang, R. S. Shen, L. Gu, H. Chai, X. Q. Wang, D. | CNS Neurosci Ther | 2023 |
osteoarthritis, postoperative delirium, smoking, total knee arthroplasty |
| Neurological Examination Frequency and Time-to-Delirium After Traumatic Brain Injury | Chotai, S. Chen, J. W. Turer, R. Smith, C. Kelly, P. D. Bhamidipati, A. Davis, P. McCarthy, J. T. Bendfeldt, G. A. Peyton, M. B. Dennis, B. M. Terry, D. P. Guillamondegui, O. Yengo-Kahn, A. M. | Neurosurgery | Neurological Examination Frequency and Time-to-Delirium After Traumatic Brain Injury |
neurological, traumatic brain injury, delirium, time-to-delirium, ICU, CAM-ICU |
| Effect of inhaled anaesthetics on cognitive and psychiatric outcomes in critically ill adults: a systematic review and meta-analysis | Cuninghame, S. Jerath, A. Gorsky, K. Sivajohan, A. Francoeur, C. Withington, D. Burry, L. Cuthbertson, B. H. Orser, B. A. Martin, C. Owen, A. M. Slessarev, M. | Br J Anaesth | 2023 |
cognition, critical care medicine, delirium, post-ICU syndrome, psychiatric, sedation |
| The Delirium Interview as a new reference standard in studies on delirium assessment tools | Ditzel, F. L. Slooter, A. J. C. van den Boogaard, M. Boonstra, M. van Nesselrooij, T. A. Kromkamp, M. Pop-Purceleanu, M. Rood, P. J. T. Osse, R. J. Chan, C. K. MacLullich, A. M. J. Tieges, Z. Neufeld, K. J. Hut, S. C. A. | J Am Geriatr Soc | 2023 |
Humans, Male, Aged, Aged, 80 and over, Female, Prospective Studies, *Intensive Care Units, *Delirium/diagnosis, Critical Care, Reference Standards, cognitive assessment, delirium, neuropsychological tests, reference standard |
| Development and validation of an international preoperative risk assessment model for postoperative delirium | Dodsworth, B. T. Reeve, K. Falco, L. Hueting, T. Sadeghirad, B. Mbuagbaw, L. Goettel, N. Schmutz Gelsomino, N. | Age Ageing | 2023 |
Humans, Aged, *Emergence Delirium/complications, *Delirium/diagnosis/etiology/prevention & control, Risk Factors, Postoperative Complications/diagnosis/etiology/prevention & control, Risk Assessment, C-Reactive Protein, algorithm, clinical practice, older people, postoperative delirium, risk prediction |
| Emergency Department Length of Stay Is Associated with Delirium in Older Adults | Elder, N. M. Mumma, B. E. Maeda, M. Y. Tancredi, D. J. Tyler, K. R. | West J Emerg Med | 2023 |
Humans, Female, Aged, Male, Length of Stay, Retrospective Studies, *Delirium/epidemiology, Prospective Studies, Risk Factors, Emergency Service, Hospital, *Dementia |
| 'It's tough. It is hard': A qualitative interview study of staff and volunteers caring for hospice in-patients with delirium | Featherstone, I. Siddiqi, N. Jones, L. Coppo, E. Sheldon, T. Hosie, A. Wolkowski, A. Bush, S. H. Taylor, J. Teodorczuk, A. Johnson, M. J. | Palliat Med | 2023 |
Humans, *Hospices, Palliative Care/psychology, *Hospice Care, Qualitative Research, Volunteers, *Delirium/therapy, Delirium, hospices, palliative care, psychological distress, qualitative research |
| Metabolic syndrome and the risk of postoperative delirium and postoperative cognitive dysfunction: a multi-centre cohort study | Feinkohl, I. Janke, J. Slooter, A. J. C. Winterer, G. Spies, C. Pischon, T. | Br J Anaesth | 2023 |
cholesterol, epidemiology, metabolic syndrome, obesity, postoperative cognitive dysfunction, postoperative delirium |
| Delirium After Traumatic Brain Injury: Prediction by Location and Size of Brain Lesion | Han, S. J. Suh, J. H. Lee, J. Y. Kim, S. J. | Ann Rehabil Med | 2023 |
Delirium, Intracranial hemorrhages, Traumatic brain injury |
| Meta-analysis of the effect of entropy-assisted general anesthesia on the quality of postoperative recovery | He, B. Zhang, N. Peng, M. | Medicine (Baltimore) | 2023 |
Humans, Postoperative Nausea and Vomiting/epidemiology/prevention & control, *Emergence Delirium, Entropy, *Intraoperative Awareness, Anesthesia, General/adverse effects, Randomized Controlled Trials as Topic |
| Sex-specific clinical characteristics and treatment responses in delirium management: findings from a prospective cohort study in elderly patients | Hildenbrand, F. F. Boettger, S. Spiller, T. Schubert, M. Ernst, J. von Känel, R. Zipser, C. M. | Int Clin Psychopharmacol | 2023 |
delirium, incidence, sex differences, observational, elderly |
| A predictive scoring system for postoperative delirium in the elderly patients with intertrochanteric fracture | Hu, Y. Yang, M. | BMC Surg | 2023 |
Humans, Aged, Infant, Retrospective Studies, *Emergence Delirium/etiology, *Fracture Fixation, Intramedullary/adverse effects, Treatment Outcome, *Hip, Fractures/complications/surgery, *Stroke/etiology, Elderly, Intertrochanteric fracture, Postoperative delirium, Prediction, Reduction and internal fixation, Scoring system |
| A single preoperative low-dose dexamethasone may reduce the incidence and severity of postoperative delirium in the geriatric intertrochanteric fracture patients with internal fixation surgery: an exploratory analysis of a randomized, placebo-controlled t | Huang, J. W. Yang, Y. F. Gao, X. S. Xu, Z. H. | J Orthop Surg Res | 2023 |
Humans, Aged, *Emergence Delirium/drug therapy, Postoperative, Complications/epidemiology/etiology/prevention & control, Prospective Studies |
| Incidence of postoperative delirium in older adults undergoing surgical procedures: A systematic literature review and meta-analysis | Igwe, E. O. Nealon, J. O'Shaughnessy, P. Bowden, A. Chang, H. R. Ho, M. H. Montayre, J. Montgomery, A. Rolls, K. Chou, K. R. Chen, K. H. Traynor, V. Smerdely, P. | Worldviews Evid Based Nurs | 2023 |
Humans, Aged, *Emergence Delirium/complications, *Delirium/epidemiology/etiology/diagnosis, Postoperative, Complications/epidemiology/etiology, Incidence, Risk Factors, meta-analysis |
| Music to prevent deliriUm during neuroSurgerY (MUSYC): a single-centre, prospective randomised controlled trial | Kappen, P. R. Mos, M. I. Jeekel, J. Dirven, C. M. F. Kushner, S. A. Osse, R. J. Coesmans, M. Poley, M. J. van Schie, M. S. van der Holt, B. Klimek, M. Vincent, Ajpe | BMJ Open | 2023 |
Adult, Humans, *Music, *Neurosurgery, Prospective Studies, *Delirium/etiology/prevention & control/diagnosis, Neurosurgical, Procedures/adverse effects, clinical trials, complementary medicine, delirium & cognitive disorders, neurosurgery, preventive medicine |
| Intraoperative suggestions to prevent postoperative delirium in patients undergoing transaortic valvular replacement: a randomized placebo-controlled trial | Kaufmann, C. Zech, N. Brandt, F. Hilker, M. Debl, K. Creutzenberg, M. Zeman, F. Graf, B. M. Sinner, B. | Aging Clin Exp Res | 2023 |
Intraoperative suggestions, Postoperative delirium, Transcatheter aortic valve replacement |
| Association of cervical atherosclerosis on Doppler ultrasonography and postoperative delirium in patients undergoing spinal surgery: a single-center, retrospective, observational study | Kumagai, G. Wada, K. Asari, T. Nitobe, Y. Kinoshita, H. Kushikata, T. Hirota, K. Ishibashi, Y. | Eur Spine J | 2023 |
Cervical atherosclerosis, Older age, Postoperative delirium, Spinal surgery, Ultrasonography |
| Educational intervention for family caregivers of older adults with delirium: An integrative review | Lee, J. Yeom, I. Yoo, S. Hong, S. | J Clin Nurs | 2023 |
education, family, older patients, review |
| The presence of preoperative neurodegeneration biofluid markers in patients with postoperative delirium | Leung, J. M. Rojas, J. C. Tang, C. Chan, B. Lario-Lago, A. Boxer, A. L. Do, Q. Kramer, J. H. Du, Z. Du, P. Sands, L. P. | Anesthesiology | 2023 |
postoperative delirium, surgical, neurodegeneration, confusion assessment method, biomarkers |
| Visual Dysfunction is a Risk Factor of Post-operation Delirium in Parkinson's Disease | Li, C. Lian, C. Wu, Q. Q. Hou, Y. Zhao, W. B. Wang, X. Zhang, C. | World Neurosurg | 2023 |
Dbs, Pod, Parkinson ’s disease, Visual impairment |
| Relationship between in-hospital angiotensin converting enzyme inhibitors and Angiotensin receptor blockers administration and delirium in the cardiac ICU | Mulkey, M. A. Hauser, P. H. P. Aucoin, J. | Hosp Pract (1995) | 2023 |
ACE inhibitor, Angiotensin receptor blocker, Antihypertensives, cardiac intensive care unit, delirium |
| Predictors of cognitive impairment in patients undergoing ileostomy for colorectal cancer: a retrospective analysis | Xu, J. Yang, Y. Hu, D. | PeerJ | 2023 |
Humans, Retrospective Studies, Ileostomy, Quality of Life, *Cognitive, Dysfunction/diagnosis, *Postoperative Cognitive Complications, *Delirium |
| The effect of music therapy on delirium in patients receiving mechanical ventilatory support in the Intensive Care Unit: A protocol for systematic review and meta-analysis | Zhou, C. Ma, H. Qi, X. Xu, C. Liang, Z. | Medicine (Baltimore) | 2023 |
Humans, *Delirium/drug therapy, Intensive Care Units, *Meta-Analysis as Topic, *Music Therapy, *Systematic Reviews as Topic/methods |
| Incidence of and risk factors for post-intensive care syndrome among Chinese respiratory intensive care unit patients: A cross-sectional, prospective study | Zhou, M. Zhang, J. Xu, Z. Gu, H. Chen, Z. Ding, Y. | Aust Crit Care | 2023 |
Humans, Prospective Studies, Incidence, *Quality of Life, Cross-Sectional Studies, *Activities of Daily Living, East Asian People, Intensive Care Units, Risk Factors, Effect factors, Patients, Post–intensive care syndrome, Respiratory intensive care unit |
| The Impact of an Educational Programme on Jordanian Intensive Care Nurses' Knowledge, Attitudes, and Practice Regarding Delirium and their Levels of Self-Efficacy: A Quasi-Experimental Design | Alhalaiqa, F. Masa'Deh, R. Al Omari, O. Shawashreh, A. Khalifeh, A. H. Gray, R. | Iran J Nurs Midwifery Res | 2023 |
Attitude, delirium, education, intensive care units, knowledge, self efficacy |
| Nonpharmacological interventions for agitation in the adult intensive care unit: A systematic review | Adams, A. M. N. Chamberlain, D. Grønkjær, M. Brun Thorup, C. Conroy, T. | Aust Crit Care | 2023 |
Adult, Humans, Intensive Care Units, Psychomotor Agitation/therapy, Critical care, Delirium, Intensive care unit, Nonpharmacological interventions, Nursing, Psychomotor agitation, Systematic review |
| Postoperative Outcomes in Elderly Patients Undergoing Cardiac Surgery With Preoperative Cognitive Impairment: A Systematic Review and Meta-Analysis | Au, E. Thangathurai, G. Saripella, A. Yan, E. Englesakis, M. Nagappa, M. Chung, F. | Anesth Analg | 2023 |
Human, Aged, Delirium/etiology/complications, Cognitive, Dysfunction/complications, Postoperative Complications/diagnosis/etiology, Cardiac Surgical Procedures/adverse effect, Intensive Care Units |
| The prediction of postoperative delirium with the preoperative bispectral index in older aged patients: a cohort study | Bao, L. Liu, T. Zhang, Z. Pan, Q. Wang, L. Fan, G. Li, Z. Yin, Y. | Aging Clin Exp Res | 2023 |
Bis, Elderly patients, Monitoring, Postoperative delirium, Prediction, Preoperative predictive score |
| Insulin resistance, age and depression's impact on cognition in middle-aged adults from the PREVENT cohort | Bauermeister, S. D. Ben Yehuda, M. Reid, G. Howgego, G. Ritchie, K. Watermeyer, T. Gregory, S. Terrera, G. M. Koychev, I. | BMJ Ment Health | 2023 |
Middle Aged, Humans, Adult, Aged, Diabetes Mellitus, Type 2/epidemiology, Insulin Resistance, Depression/epidemiology, Cohort Studies, Cross-Sectional Studies, Cognition, Alzheimer Disease/psychology, delirium & cognitive disorders, depression & mood disorders, psychiatry |
| Key elements of an evidence-based clinical psychology service within adult critical care | Beadman, M. Carraretto, M. | J Intensive Care Soc | 2023 |
Psychology, critical care, delirium, follow-up clinics, post-intensive care syndrome |
| Neurofilament light chains to assess sepsis-associated encephalopathy: Are we on the track toward clinical implementation? | Bircak-Kuchtova, B. Chung, H. Y. Wickel, J. Ehler, J. Geis, C. | Crit Care | 2023 |
Humans, Sepsis-Associated Encephalopathy/complications/diagnosis, Intermediate Filaments, Sepsis/complications/diagnosis, Biomarkers, Brain Diseases, Biomarker, Brain dysfunction, Delirium, Encephalopathy, Neurofilament light chain, Sae, Sepsis |
| Veterans' experiences of moral injury, treatment and recommendations for future support | Bonson, A. Murphy, D. Aldridge, V. Greenberg, N. Williamson, V. | BMJ Mil Health | 2023 |
anxiety disorders, delirium & cognitive disorders, depression & mood disorders, public health |
| General Anesthesia Versus Regional Anesthesia in the Elderly Patients Undergoing Hip Fracture Surgeries: A Systematic Review and Meta-Analysis of Randomized Clinical Trials | Cao, M. M. Zhang, Y. W. Sheng, R. W. Gao, W. Kang, Q. R. Gao, Y. C. Qiu, X. D. Rui, Y. F. | World J Surg | 2023 |
Humans, Aged, Emergence Delirium, Blood Loss, Surgical/prevention & control, Postoperative Complications/epidemiology/etiology, Randomized Controlled Trials as Topic, Anesthesia, General, Anesthesia, Conduction, Hip Fractures/surgery |
| Delirium in ventilated patients receiving fentanyl and morphine for Analgosedation: Findings from the ANALGESIC trial | Casamento, A. Neto, A. S. Lawrence, M. Chudleigh, L. Browne, E. Taplin, C. Eastwood, G. M. Bellomo, R. | J Crit Care | 2023 |
Analgosedation, Delirium, Mechanical ventilation, Opioids |
| Postoperative delirium after intracranial neurosurgery: A prospective cohort study from a developing nation | Chakrabarti, D. Bharadwaj, S. Akash, V. S. Wadhwa, A. Konar, S. Kamath, S. Gopalakrishna, K. N. | Acta Neurochir (Wien) | 2023 |
Humans, Emergence Delirium/complications, Delirium/epidemiology/etiology |
| Incidence of preoperative instrumental activities of daily living (IADL) dependence and adverse outcomes in older surgical patients: A systematic review and meta-analysis | Chen, A. An, E. Yan, E. He, D. Saripella, A. Butris, N. Tsang, J. Englesakis, M. Wong, J. Alibhai, S. Chung, F. | J Clin Anesth | 2023 |
Delirium, systematic review and meta-analysis, Functional dependence,, Instrumental activities of daily living (IADL), Older patients, Preoperative assessment |
| Heterogeneity in the definition of delirium in ICUs and association with the intervention effect in randomized controlled trials: a meta-epidemiological study | Collet, L. Lanore, A. Alaterre, C. Constantin, J. M. Martin, G. L. Caille, A. James, A. Dechartres, A. | Crit Care | 2023 |
Humans, Delirium/diagnosis/epidemiology/therapy, Epidemiologic Studies, Intensive Care Units, Randomized Controlled Trials as Topic, Meta-Analysis as Topic, Definition, Delirium, Heterogeneity, Intensive care, Meta-analysis, Meta-epidemiology |
| A prospective multicentre observational study to quantify nocturnal light exposure in intensive care | Craig, T. Mathieu, S. Morden, C. Patel, M. Matthews, L. | J Intensive Care Soc | 2023 |
Light, circadian rhythm, delirium, environment, light pollution |
| Recognizing and Reducing Delirium in the Intensive Care Unit | Dechant, T. Smith, L. Chavez, J. | Crit Care Nurs Q | 2023 |
Humans, Disease Progression, Intensive Care Units |
| Postoperative Deep Sedation after Microvascular Reconstructive Surgery for Oral Cancer Increases the Risk of Early Postoperative Pneumonia | Fukuzawa, S. Yamagata, K. Takaoka, S. Uchida, F. Ishibashi-Kanno, N. Yanagawa, T. Bukawa, H. | Dent J (Basel) | 2023 |
oral cancer, postoperative delirium, postoperative pneumonia, postoperative sedation, reconstructive surgery |
| Heart rate response and recovery during exercise predict future delirium risk-A prospective cohort study in middle- to older-aged adults | Gao, L. Gaba, A. Li, P. Saxena, R. Scheer, Fajl Akeju, O. Rutter, M. K. Hu, K. | J Sport Health Sci | 2023 |
Male, Humans, Adult, Middle Aged, Female, Heart Rate/physiology, Prospective Studies, Exercise/physiology, Risk Factors, Delirium, Brain health, Delirium, Exercise stress test |
| Circadian Rest-Activity Rhythms, Delirium Risk, and Progression to Dementia | Gao, L. Li, P. Gaykova, N. Zheng, X. Gao, C. Lane, J. M. Saxena, R. Scheer, Fajl Rutter, M. K. Akeju, O. Hu, K. | Ann Neurol | 2023 |
Middle Aged, Humans, Sleep, Circadian Rhythm, Rest, Actigraphy, Sleep Wake Disorders, Dementia/etiology, Delirium/etiology |
| Frequency and Risk Factors of Subsyndromal Delirium in the Intensive Care Units: A Prospective Cohort Study | Gao, Y. Gong, S. Zhou, W. Li, X. Gan, X. | Neuropsychiatr Dis Treat | 2023 |
Icu, intensive care units, prevalence, risk factors, subsyndromal delirium |
| Calibration of the PREdiction of DELIRium in ICu Patients (PRE-DELIRIC) Score in a Cohort of Critically Ill Patients: A Retrospective Cohort Study | Gravante, F. Giannarelli, D. Pucci, A. Pisani, L. Latina, R. | Dimens Crit Care Nurs | 2023 |
Humans, Calibration, Critical Illness, Retrospective Studies, Nonoxynol, Delirium, Intensive Care Units |
| Surgeon-Specific Treatment Selection Bias and Heterogeneous Perioperative Practices in an Observational Spine Surgery Study. A Statistical Tutorial with Implications for Analysis of Observational Studies of Perioperative Interventions | Hindman, B. J. Gold, C. J. Ray, E. Wendt, L. H. Ten Eyck, P. Berger, J. I. Olinger, C. R. Banks, M. I. Sanders, R. D. Howard, M. A., 3rd Woodroffe, R. W. | World Neurosurg | 2023 |
Adult, Humans, Antifibrinolytic Agents/therapeutic use, Retrospective Studies, Selection Bias, Tranexamic Acid/therapeutic use, Blood Loss, Surgical, Surgeons, Delirium, Logistic regression, Propensity score, Spinal fusion, Surgical technique, Tranexamic acid |
| Relationship Between Delirium Development and Its Causative Factors in the Intensive Care Unit After Cardiac Surgery | Hori, Y. Mihashi, M. | Yonago Acta Med | 2023 |
cardiac surgery, delirium, intensive care unit, postoperative complications, risk factors |
| Effect of Repeated Intranasal Administration of Different Doses of Insulin on Postoperative Delirium, Serum τ and Aβ Protein in Elderly Patients Undergoing Radical Esophageal Cancer Surgery | Huang, Q. Shi, Q. Yi, X. Zeng, J. Dai, X. Lin, L. Yang, Y. Wu, X. Gong, G. | Neuropsychiatr Dis Treat |
Aβ protein, aged, intranasal insulin, postoperative delirium, τ protein |
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| Delirium screening in a stroke unit by nurses using 4AT: Results from a quality improvement project | Ihle-Hansen, H. Johnsen, N. Jankowiak, T. Hagberg, G. Walle-Hansen, M. M. Landgraff, I. Høvik, G. Graven, E. Myrstad, M. | Nurs Open | 2023 |
4at, delirium, minor stroke, nurse, post-stroke |
| A Review of Biomarkers in Delirium Superimposed on Dementia (DSD) and Their Clinical Application to Personalized Treatment and Management | Jahangir, S. Allala, M. Khan, A. S. Muyolema Arce, V. E. Patel, A. Soni, K. Sharafshah, A. | Cureus | 2023 |
bioinformatics, delirium, delirium superimposed dementia, dementia, geriatrics, hsa-mir-17, neurology, psychiatry |
| Factors Affecting Delirium in ICU Patients | Jeong, I. S. Cho, M. K. | Int J Environ Res Public Health | 2023 |
Humans, Retrospective Studies, Delirium/diagnosis/epidemiology, Intensive Care Units, Hypnotics and Sedatives, Pain/complications, Risk Factors, Glasgow coma scale, blood urea nitrogen, delirium, intensive care unit, length of stay, morse fall scale, restraints, simplified acute physiology score |
| The Combined Effect of Delirium and Falls on Length of Stay and Discharge | Kalivas, B. Zhang, J. Harper, K. Dulin, J. Heincelman, M. Marsden, J. Hunt, K. J. Mauldin, P. D. Moran, W. P. Thomas, M. K. | J Healthc Qual | 2023 |
Humans, Length of Stay, Patient Discharge, Cross-Sectional Studies, Hospitalization, Delirium, Retrospective Studies |
| Effect of using eye masks and earplugs in preventing delirium in intensive care patients: A single-blinded, randomized, controlled trial | Kiliç, G. Kav, S. | Nurs Crit Care | 2023 |
delirium, earplugs, eye masks, intensive care unit (ICU), nonpharmacological interventions |
| Computed tomographic bone mineral density is independently associated with adverse in-hospital outcomes in Dutch level-1 trauma patients | Kobes, T. Sweet, A. A. R. Verstegen, S. B. H. Houwert, R. M. Veldhuis, W. B. Leenen, L. P. H. de Jong, P. A. van Baal, Mcpm | Eur J Trauma Emerg Surg | 2023 |
Male, Humans, Middle Aged, Female, Bone Density, Osteoporosis, Absorptiometry, Photon/methods, Tomography, X-Ray Computed/methods, Lumbar Vertebrae/diagnostic imaging, Hospitals, Delirium, Retrospective Studies, Bone mineral density, Computed tomography, In-hospital complications, Opportunistic screening, Trauma patients |
| Yokukansan (TJ-54) in patients undergoing surgery: A systematic review and meta-analysis | Kotake, K. Matsunuma, S. Takahashi, T. Kitamura, N. Kawakami, Y. | Geriatr Nurs | 2023 |
Adverse events, Anxiety, Postoperative delirium, Systematic review, Yokukansan |
| Pattern of Inpatient Consultation-liaison Psychiatry Utility in a Tertiary Care Hospital | Kumar, P. Chaudhary, R. Bhalla, J. K. Gupta, A. | Int J Appl Basic Med Res | 2023 |
Consultation liaison psychiatry, delirium, drug withdrawal, emergency |
| Machine learning-based prediction model for postoperative delirium in non-cardiac surgery | Lee, D. Y. Oh, A. R. Park, J. Lee, S. H. Choi, B. Yang, K. Kim, H. Y. Park, R. W. | BMC Psychiatry | 2023 |
Humans, Male, Emergence Delirium, Algorithms, Area Under Curve, Hospitals, Machine Learning, Delirium, Non-cardiac surgery |
| Preoperative slow-wave sleep is associated with postoperative delirium after heart valve surgery: A prospective pilot study | Lin, Y. Xu, S. Peng, Y. Li, S. Huang, X. Chen, L. | J Sleep Res | 2023 |
delirium, sleep architecture, slow-wave sleep, valve surgery |
| The relationship between major depression and delirium: A two-sample Mendelian randomization analysis | Li, J. Wang, J. Yang, M. Wang, G. Xu, P. | J Affect Disord | 2023 |
Delirium, Depression, Genetic, Mendelian randomization |
| Preoperative cerebrospinal fluid biomarkers may be associated with postoperative delirium in patients undergoing knee/hip arthroplasty: the PNDABLE study | Lin, Y. Yu, N. Lin, X. Deng, X. Liu, F. Tao, H. Dong, R. Wang, B. Bi, Y. | BMC Geriatr | 2023 |
Humans, Aged, Amyloid beta-Peptides/cerebrospinal fluid, Emergence Delirium, Arthroplasty, Replacement, Hip/adverse effects, Aging, Biomarkers/cerebrospinal fluid, Peptide Fragments, Alzheimer Disease/diagnosis |