Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Processed electroencephalogram and evoked potential techniques for amelioration of postoperative delirium and cognitive dysfunction following non-cardiac and non-neurosurgical procedures in adults.
Authors
Punjasawadwong, Y. Chau-In, W. Laopaiboon, M. Punjasawadwong, S. Pin-On, P.
Year
2018
Journal
Cochrane Database of Systematic Reviews
Abstract

BACKGROUND: Postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) may complicate a patient’s postoperative recovery in several ways. Monitoring of processed electroencephalogram (EEG) or evoked potential (EP) indices may prevent or minimize POD and POCD, probably through optimization of anaesthetic doses. OBJECTIVES: To assess whether the use of processed EEG or auditory evoked potential (AEP) indices (bispectral index (BIS), narcotrend index, cerebral state index, state entropy and response entropy, patient state index, index of consciousness, A-line autoregressive index, and auditory evoked potentials (AEP index)) as guides to anaesthetic delivery can reduce the risk of POD and POCD in non-cardiac surgical or non-neurosurgical adult patients undergoing general anaesthesia compared with standard practice where only clinical signs are used. SEARCH METHODS: We searched CENTRAL, MEDLINE, Embase and clinical trial registry databases up to 28 March 2017. We updated this search in February 2018, but these results have not been incorporated in the review. SELECTION CRITERIA: We included randomized or quasi-randomized controlled trials comparing any method of processed EEG or evoked potential techniques (entropy, BIS, AEP etc.) against a control group where clinical signs were used to guide doses of anaesthetics in adults aged 18 years or over undergoing general anaesthesia for non-cardiac or non-neurosurgical elective operations. DATA COLLECTION AND ANALYSIS: We used the standard methodological procedures expected by Cochrane. Our primary outcomes were: occurrence of POD; and occurrence of POCD. Secondary outcomes included: all-cause mortality; any postoperative complications; and postoperative length of stay. We used GRADE to assess the quality of evidence for each outcome. MAIN RESULTS: We included six randomized controlled trials (RCTs) with 2929 participants comparing processed EEG or EP indices-guided anaesthesia with clinical signs-guided anaesthesia. There are five ongoing studies and one study awaiting classification.Anaesthesia administration guided by the indices from a processed EEG (bispectral index) probably reduces the risk of POD within seven days after surgery with risk ratio (RR) of 0.71 (95% CI 0.59 to 0.85; number needed to treat for an additional beneficial outcome (NNTB) of 17, 95% CI 11 to 34; 2197 participants; 3 RCTs; moderate quality of evidence). Three trials also showed the lower rate of POCD at 12 weeks after surgery (RR 0.71, 95% CI 0.53 to 0.96; NNTB 38, 95% CI 21 to 289; 2051 participants; moderate-quality evidence), but it is uncertain whether processed EEG indices reduce POCD at one week (RR 0.84, 95% CI 0.69 to 1.02; 3 trials; 1989 participants; moderate-quality evidence), and at 52 weeks (RR 0.30, 95% CI 0.05 to 1.80; 1 trial; 59 participants; very low quality of evidence). There may be little or no effect on all-cause mortality (RR 1.01, 95% CI 0.62 to 1.64; 1 trial; 1155 participants; low-quality evidence). One trial suggested a lower risk of any postoperative complications with processed EEG (RR 0.51, 95% CI 0.37 to 0.71; 902 participants, moderate-quality evidence). There may be little or no effect on reduced postoperative length of stay (mean difference -0.2 days, 95% CI -2.02 to 1.62; 1155 participants; low-quality evidence). AUTHORS’ CONCLUSIONS: There is moderate-quality evidence that optimized anaesthesia guided by processed EEG indices could reduce the risk of postoperative delirium in patients aged 60 years or over undergoing non-cardiac surgical and non-neurosurgical procedures. We found moderate-quality evidence that postoperative cognitive dysfunction at three months could be reduced in these patients. The effect on POCD at one week and over one year after surgery is uncertain. There are no data available for patients under 60 years. Further blinded randomized controlled trials are needed to elucidate strategies for the amelioration of postoperative delirium and postoperative cognitive dysfunction, and their consequences such as dementia (including Alzheimer’s disease (AD)) in both non-elderly (below 60 years) and elderly (60 years or over) adult patients. The one study awaiting classification and five ongoing studies may alter the conclusions of the review once assessed.

PMID

29761891

Keywords
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Total Records Found: 6289, showing 100 per page
TitleAuthorsJournalYearKeywords
Effect of clock rhythm on emergence agitation and early postoperative delirium in older adults undergoing thoracoscopic lung cancer surgery: protocol for a prospective, observational, cohort study Jiang, L. Wang, J. Chen, W. Wang, Z. Xiong, W. BMC Geriatr 2024

Humans
Aged
*Emergence Delirium/epidemiology
*Melatonin
Prospective Studies
Cohort Studies
*Lung Neoplasms
Postoperative Complications/epidemiology
Observational Studies as Topic
Clock rhythm
Early postoperative delirium
Emergence agitation
Older adults

Scientific rationale for the use of α2A-adrenoceptor agonists in treating neuroinflammatory cognitive disorders Arnsten, A. F. T. Ishizawa, Y. Xie, Z. Mol Psychiatry 2023

Humans
Calcium Signaling
*Cognitive Dysfunction
*Delirium
Guanfacine/pharmacology/therapeutic use
Neuroinflammatory Diseases
Post-Acute COVID-19 Syndrome
Prefrontal Cortex

The role of perioperative sedative anesthetics in preventing postoperative delirium: a systematic review and network-meta analysis including 6679 patients Huang, J. X. Zhang, S. S. Wang, S. X. Xi, D. S. Luo, F. R. Liu, C. J. Li, H. BMC Cardiovasc Disord 2024

PMID: 38448835

PMCID: PMC10916082

Preventive Effects of Melatonin on Delirium in Intensive Care Unit Patients: A Meta-Analysis of Randomized Controlled Trials Zhao, L. Feng, Z. Wang, Q. Jiang, Z. Qiu, X. Altern Ther Health Med 2024

ICU

Delirium

Melatonin

Length of Stay

Meta-Analysis

Mechanical Ventilation

Mitochondrial Dysfunction of Peripheral Platelets as a Predictive Biomarker for Postoperative Delirium in Elderly Patients Yang, Y. Zhang, W. Liu, Y. Liu, X. Xie, J. Xu, R. Huang, Y. Hao, J. Sun, Y. Gu, X. Ma, Z. Ann Neurol 2024

Postoperative Delirium

Bioenergetic Health Index

Surgery

Mitochondria

MMSE

 

Effect of Esketamine on Postoperative Delirium in Patients Undergoing Cardiac Valve Replacement with Cardiopulmonary Bypass: A Randomized Controlled Trial Xiong, X. Shao, Y. Chen, D. Chen, B. Lan, X. Shi, J. Anesth Analg 2024

Postoperative Delirium

Esketamine

Cardiac Valve Replacement

Cardiopulmonary Bypass

CAM

CAM-ICU

MMSE

Prolonged Hourly Neurologic Examinations are Associated with Increased Delirium and No Discernible Benefit in Mild/Moderate Geriatric Traumatic Brain Injury Ruiz, R. A. F. Canas, M. Diaz, L. Aldana, J. A. Afzal, H. Falcon, A. F. Del Toro, D. Day, A. McCarthy, J. Stansfield, K. Bochicchio, G. V. Niziolek, G. Kranker, L. M. Rosengart, M. R. Hoofnagle, M. Leonard, J. J Trauma Acute Care Surg 2024

NeuroChecks

Delirium

TBI

CAM-ICU

Association of Intravenous Neostigmine and Anticholinergics or Sugammadex with Postoperative Delirium: A Retrospective Cohort Study Rössler, J. Abramczyk, E. Paredes, S. Anusic, N. Pu, X. Maheshwari, K. Turan, A. Ruetzler, K. Anesth Analg 2024

bCAM

Postoperative Delirium

Sugammadex

Neostigmine

Anesthesia

Noncardiac Surgery

Metformin Use in Type 2 Diabetics and Delirium After Noncardiac Surgery: A Retrospective Cohort Analysis Paredes, S. Harb, A. Rössler, J. Nikoo, M. Z. Ruetzler, K. Turan, A. Pu, X. Sessler, D. I. Anesth Analg 2024

Type 2 Diabetes

CAM-ICU

bCAM

Postoperative Delirium

Metformin

 

Preoperative Intrathecal Morphine is Associated With Reduced Postoperative Pain, Agitation, and Delirium In Living Donor Kidney Transplantation Recipients Lee, J. E. Lee, K. W. Gil, E. Park, J. B. Kim, B. J. Kim, H. Y. Kim, G. S. Transplant Proc 2024

Kidney Transplant

Postoperative Delirium

Intrathecal Morphine

CAM-ICU

Postoperative Pain

Anesthesia

Neuropsychological follow-up of isoflurane sedated intensive care patients: a substudy of a randomized trial Fuchs, V. F. Simon, H. V. Soldinger, N. Volk, T. Meiser, A. Minerva Anestesiol 2024

Critical care

Isoflurane

Propofol

Delirium

Feasibility and Acceptability of Using Wireless Limited Polysomnography to Capture Sleep Before, During, and After Hospitalization for Patients With Planned Cardiothoracic Surgery Cordoza, M. L. Anderson, B. J. Cevasco, M. Diamond, J. M. Younes, M. Gerardy, B. Iroegbu, C. Riegel, B. J Cardiovasc Nurs 2024

Critical Illness

Intensive Care Unit

Polysomnography

Sleep

Thoracic Surgery

Antipsychotics in the Treatment of Delirium in Critically Ill Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Carayannopoulos, K. L. Alshamsi, F. Chaudhuri, D. Spatafora, L. Piticaru, J. Campbell, K. Alhazzani, W. Lewis, K. Crit Care Med 2024

Antipsychotic medication

Delirium

Systematic review

Critically Ill

Cognitive Impairment

Coma

Burnout and perceived burden levels related to delirium in physicians and nurses Yamagata, H. Takihara, T. Kobayashi, R. Hirose, K. Higuchi, K. Miyahara, M. Komatsu, D. Gen Hosp Psychiatry 2024

Humans
*Burnout, Professional/epidemiology
Burnout, Psychological
*Physicians
*Delirium/epidemiology
Surveys and Questionnaires
*Nurses

Bell's mania as a clinical presentation in a neurosurgical setting from a tertiary care neuropsychiatric hospital in India Mamtani, H. Utagi, S. Chaurasia, K. K. Reddy, P. V. Arasappa, R. Prasad, C. Srinivas, D. Rao, M. B. Thippeswamy, H. Indian J Psychiatry 2024

Craniopharyngioma
delirious mania
delirium
dural arteriovenous fistula
mania

Correlation analysis between plasma biomarkers albumin, fibrinogen, and their ratio with postoperative delirium in patients undergoing non-cardiac surgery: a systematic review and meta-analysis Lu, Z. Wang, B. Liu, M. Yu, D. Li, J. Am J Transl Res 2024

Albumin
albumin-fibrinogen ratio (AFR)
fibrinogen
meta-analysis
plasma biomarkers
postoperative delirium

Risk factors for hypoactive delirium in patients with nontraumatic ARDS: a prospective observational study Lian, F. Li, F. Tang, X. Yuan, Y. Sci Rep 2024

Humans
Interleukin-6
*Respiratory Distress Syndrome/complications/therapy
Intensive Care Units
Risk Factors
Hypokinesia
*Diabetes Mellitus
*Delirium/epidemiology/etiology/diagnosis
Retrospective Studies
Hypoactive delirium
Il-6
Intensive care unit
Nontraumatic ARDS
Risk factor

Current Practices and Attitudes of Cardiac Nurses Regarding Cognitive Screening in Patients With Acute Coronary Syndrome Zhao, E. Lowres, N. Bloomfield, J. Weddell, J. Tofler, G. Gallagher, R. Heart Lung Circ 2024

Acute coronary syndrome
Cardiac nurses
Cognitive impairment
Cognitive screening

Related factors of delirium after transsphenoidal endoscopic pituitary adenoma resection-A matched retrospective cohort study Zhang, S. Chen, Y. Wang, X. Liu, J. Chen, Y. Zhang, G. J Clin Neurosci 2024

Neuroendoscopy
Perioperative nursing
Pituitary adenoma
Postoperative delirium

Prevalence of post-stroke delirium in acute settings: A systematic review and meta-analysis Ye, F. Ho, M. H. Lee, J. J. Int J Nurs Stud 2024

Acute setting
Delirium
Meta-analysis
Prevalence
Stroke
Systematic review

Predictive factors for postoperative delirium in thoracic surgery Yaguchi, T. Ichinokawa, H. Kirino, E. Suzuki, M. Komori, K. Matsunaga, T. Takamochi, K. Suzuki, K. Gen Thorac Cardiovasc Surg 2024

Postoperative delirium
Risk factor
Thoracic surgery

Preoperative cognitive impairment and postoperative delirium among Holocaust survivors who achieved longevity Weiss, Y. Zarour, S. Kiselevich, Y. Abu Ghanim, M. Hikry, D. Sinai Brzezinski, I. Zac, L. Cohen, B. Matot, I. J Am Geriatr Soc 2024

Holocaust
anesthesia
delirium
loneliness
perioperative

Substance use problems and disorders among adults 50 years and older receiving mental health treatment for a primary neurocognitive disorder Ware, O. D. Baik, S. Becker, T. D. Neukrug, H. Zimmerman, S. Aging Ment Health

Aging
co-occurring
mental health
neurocognitive disorder
substance use disorder
treatment

The risk of delirium after sedation with propofol or midazolam in intensive care unit patients van Gelder, T. G. van Diem-Zaal, I. J. Dijkstra-Kersten, S. M. A. de Mul, N. Lalmohamed, A. Slooter, A. J. C. Br J Clin Pharmacol 2024

critical care
deep sedation
delirium
intensive care units

Incidence and Risk Factors for ICU-Associated Delirium in the Alert Geriatric Trauma Population Ulderich Williams, S. C. Qaddoumi, A. I. Meghreblian, J. T. McBride, M. E. King, S. A. Elahi, M. A. Tuggle, D. Heidel, R. E. Smith, L. M. Am Surg 2024

Glasgow Coma Score
confusion assessment method
delirium
intensive care unit
trauma

Opioid use and subsequent delirium risk in patients with advanced cancer in palliative care: a multicenter registry study Yoo, S. H. Kang, J. Kim, H. J. Lee, S. W. Hong, M. Jung, E. H. Kim, Y. J. Yon, D. K. Kang, B. Sci Rep 2024

Humans
Male
Middle Aged
Female
Palliative Care
Analgesics, Opioid/therapeutic use
Retrospective Studies
Cohort Studies
*Opioid-Related Disorders/drug therapy
*Neoplasms/drug therapy
*Delirium/etiology
Cancer
Delirium
Opioid

Point prevalence and clinical profile of patients with delirium admitted in internal medicine department at tertiary care centre in eastern Nepal: a descriptive cross-sectional study Yogi, T. N. Puri, S. Shah, B. Nepal, S. Mishra, A. Ann Med Surg (Lond) 2024

alcoholism
clinical profile
delirium
elderly prevalence

Reducing the use of psychotropics in a convalescent rehabilitation ward Uematsu, T. Tomita, T. Obara, R. Gonai, T. Hattori, K. Aonuma, T. Usui, K. Tanifuji, H. Ishizawa, F. Ishii, H. Suzuki, E. Neuropsychopharmacol Rep 2024

Humans
*Psychotropic Drugs
*Antipsychotic Agents
Antidepressive Agents
Hospitals
Patient Discharge
convalescent rehabilitation ward
delirium
older adult patients
polypharmacy
psychotropics

The impact of postoperative agitated delirium on dementia in surgical patients Sun, M. Chen, W. M. Wu, S. Y. Zhang, J. Brain Commun 2024

Psm
dementia
incidence rate
postoperative agitated delirium

The impact of postoperative agitated delirium on dementia in surgical patients Sun, M. Chen, W. M. Wu, S. Y. Zhang, J. Brain Commun 2024

Psm
dementia
incidence rate
postoperative agitated delirium

Effects of human herpesvirus 6B reactivation on cognitive function in cord blood transplant recipients: a prospective multicenter study Ogata, M. Oshima, K. Takano, K. Kawano, R. Ueda, Y. Imamura, T. Nakamura, Y. Okada, T. Toubai, T. Ueki, T. Uoshima, N. Ishida, H. Shinohara, A. Seo, S. Fukuda, T. Inagaki, M. Int J Hematol 2024

Humans
*Herpesvirus 6, Human/genetics
Quality of Life
Prospective Studies
*Cord Blood Stem Cell Transplantation/adverse effects
Virus Activation
DNA, Viral
Cognition
*Delirium
*Hematopoietic Stem Cell Transplantation
Cognitive function
Cord blood transplantation
Human herpesvirus-6B
Memory function

Modification in ICU Design May Affect Delirium and Circadian Melatonin: A Proof of Concept Pilot Study Spies, C. Piazena, H. Deja, M. Wernecke, K. D. Willemeit, T. Luetz, A. Crit Care Med 2024

Adult
Humans
*Melatonin/therapeutic use
Pilot Projects
Prospective Studies
Intensive Care Units
*Delirium/epidemiology

The effect of nonpharmacological interventions applied by nurses to intensive care patients on the duration of delirium: a meta-analysis study Söylemez, G. K. Uzun, S. Ir J Med Sci 2024

Humans
*Delirium/therapy
Critical Care
Intensive Care Units
Delirium
Meta-analysis
Nonpharmacological interventions
Nurse

Prevalence, risk factors and impact of delirium in adult inpatients in a tertiary care hospital: A point prevalence study Schiess, C. Hofer, L. Von Felten, S. Bartussek, J. Petry, H. Ernst, J. J Clin Nurs 2024

cross-sectional studies
delirium
hospitals
inpatients
prevalence

The association between cerebral blood flow variations during on-pump coronary artery bypass grafting surgery and postoperative delirium Sampaolesi, C. Casarotta, E. Gresti, G. Mariotti, G. Pisani, L. Veccia, D. Di Eusanio, M. Malvindi, P. G. Donati, A. Münch, C. M. Perfusion 2024

cerebral blood flow
coronary artery bypass grafting
perioperative cognitive disorders
postoperative delirium
transcranial Doppler
of interest with respect to the research, authorship, and/or publication of this
article.

Correlation of Sedation Depth During Critical Care Transport and Hospitalization Roginski, M. A. Carroll, M. C. Trautwein, M. L. Watkins, E. D. Esteves, A. M. J Intensive Care Med 2024

Adult
Humans
*Hypnotics and Sedatives
Retrospective Studies
Coma/therapy
*Delirium
Critical Care
Intensive Care Units
Hospitalization
Respiration, Artificial
coma
deep sedation
mechanical ventilation
prehospital
sedation

The Health Outcomes of a Telegeriatrics Follow-Up Model on Dementia Patients and Their Caregivers in Cairo Mossad, N. A. Hamza, S. A. Wahba, H. M. F. Youssif, H. Y. Tolba, M. F. Telemed J E Health 2024

caregiver satisfaction
caregiver stress
delirium
dementia
telegeriatrics
telemedicine

Protect the neck: Devastating outcomes of cervical spine fractures in the elderly Mormol, J. Krech, L. Pounders, S. Fisk, C. Chapman, A. Karek, M. Hing, K. K. Am J Surg 2024

Aged
Humans
Retrospective Studies
Aftercare
Patient Discharge
*Spinal Fractures/surgery/complications
Cervical Vertebrae/injuries
*Delirium
Cervical
Delirium
Geriatric
Outcomes
Spine
Trauma

Prevalence of clinical electroencephalography findings in stroke patients with delirium Mintz, N. B. Andrews, N. Pan, K. Bessette, E. Asaad, W. F. Sherif, M. Rubinos, C. Mahta, A. Girard, T. D. Reznik, M. E. Clin Neurophysiol 2024

Delirium
Electroencephalography
Neurocritical care
Stroke

Insulin resistance and osteocalcin associate with the incidence and severity of postoperative delirium in elderly patients undergoing joint replacement Mi, Y. Wen, O. Lei, Z. Ge, L. Xing, L. Xi, H. Geriatr Gerontol Int 2024

elderly patients
insulin resistance
joint replacement
osteocalcin
postoperative delirium

Single-channel qEEG characteristics distinguish delirium from no delirium, but not postoperative from non-postoperative delirium Lodema, D. Y. Ditzel, F. L. Hut, S. C. A. van Dellen, E. Otte, W. M. Slooter, A. J. C. Clin Neurophysiol

Acute encephalopathy
Delirium
Electroencephalogram
Postoperative
Random forest

A Mendelian randomization-based study of the causal relationship between leisure sedentary behavior and delirium Liu, C. Lv, X. Meng, L. Li, J. Cao, G. J Affect Disord 2024

Causal relationship
Delirium
Leisure sedentary behaviors
Mendelian randomization
Time spent watching television

Understanding family carer experiences and perceptions of engagement in delirium prevention and care for adults in hospital: Qualitative systematic review Lee-Steere, K. Mudge, A. Liddle, J. Bennett, S. J Clin Nurs 2024

Adult
Humans
*Caregivers
Hospitals
Health Personnel
Spouses
*Delirium/prevention & control
Qualitative Research
acute hospital
adult patients
delirium
family carer engagement
qualitative

The use of the DOS and Delirium Prevalence: a quantitative longitudinal study at a Swiss-German central hospital Lauffer-Vogt, S. U. Hediger, H. Lauener, S. K. Schubert, M. Pflege 2024

Female
Humans
*Delirium/diagnosis/epidemiology
Hospitals
Longitudinal Studies
Retrospective Studies
Switzerland
Male
Aged
delirium
diagnostic screening programs
prevalence
public hospital

Melatonin does not reduce delirium severity in hospitalized older adults: Results of a randomized placebo-controlled trial Lange, P. W. Turbić, A. Soh, C. H. Clayton-Chubb, D. Lim, W. K. Conyers, R. Watson, R. Maier, A. B. J Am Geriatr Soc 2024

aged neurocognitive disorders
delirium
inpatients
melatonin
sepsis-associated encephalopathy
sleep wake disorders

Immunological Analysis of Postoperative Delirium after Thoracic Aortic Surgery Ko, H. Kayumov, M. Lee, K. S. Oh, S. G. Na, K. J. Jeong, I. S. J Chest Surg 2024

Aorta
Delirium
Intensive care units
Surgery

Risk Factors for Postoperative Cognitive Decline After Orthopedic Surgery in Elderly Chinese Patients: A Retrospective Cohort Study Li, X. Lai, H. Wang, P. Feng, S. Feng, X. Kong, C. Wu, D. Yin, C. Shen, J. Yan, S. Han, R. Liu, J. Ren, X. Li, Y. Tang, L. Xue, D. Zhao, Y. Huang, H. Li, X. Zhang, Y. Wang, X. Wang, C. Jin, P. Lu, S. Wang, T. Zhao, G. Wang, C. Clin Interv Aging 2024

Aged
Humans
Female
Aged, 80 and over
Male
*Postoperative Cognitive Complications
Sufentanil
Retrospective Studies
*Delirium
Risk Factors
*Orthopedic Procedures/adverse effects
*Anesthetics
China/epidemiology
Postoperative Complications/epidemiology/etiology
*Cognitive Dysfunction/epidemiology/etiology
cognitive dysfunction
comprehensive geriatric assessment
orthopedic surgery
postoperative cognitive complications

Clinical Impact of the Implementation Strategies Used to Apply the 2013 Pain, Agitation/Sedation, Delirium or 2018 Pain, Agitation/Sedation, Delirium, Immobility, Sleep Disruption Guideline Recommendations: A Systematic Review and Meta-Analysis Hume, N. E. Zerfas, I. Wong, A. Klein-Fedyshin, M. Smithburger, P. L. Buckley, M. S. Devlin, J. W. Kane-Gill, S. L. Crit Care Med 2024

Adult
Humans
*Critical Care/methods
Intensive Care Units
Pain
Pain Management
*Delirium/prevention & control

Delirium and incident dementia in hospital patients in New South Wales, Australia: retrospective cohort study Gordon, E. H. Ward, D. D. Xiong, H. Berkovsky, S. Hubbard, R. E. Bmj 2024

Male
Humans
Female
Aged
Aged, 80 and over
*Dementia/diagnosis
*Delirium/epidemiology/etiology/diagnosis
Retrospective Studies
New South Wales/epidemiology
Inpatients
Australia
Risk Factors
Hospitals

Effect of subanesthetic dose of esketamine on postoperative pain in elderly patients undergoing laparoscopic gastrointestinal tumor Surgery:A prospective, double-blind, randomized controlled trial Jing, Z. Han, Y. Li, Y. Zeng, R. Wu, J. Wang, Y. Jiang, P. Heliyon 2024

Analgesia
Delirium
Elderly
Esketamine
Pain
personal relationships that could have appeared to influence the work reported in
this paper.

Predictive Ability of Amplitude Integrated Electroencephalography for Adverse Outcomes in Neonates with Sepsis-Associated Encephalopathy: A Cohort Study Jain, P. Saini, S. S. Sahu, J. K. Madaan, P. Sundaram, V. Dutta, S. Indian J Pediatr 2024

Cerebral function monitor
Cerebral inflammation
Electroencephalography
Sepsis associated delirium
aEEG

Perioperative knowledge, self-efficacy and clinical practices related to postoperative delirium care in older people across geographical regions in Australia Igwe, E. O. Nealon, J. O'Shaughnessy, P. Ormonde, C. Traynor, V. Aust J Rural Health 2024

Australia
clinicians
nurses
older people
postoperative delirium
survey

A survey of non-consultant hospital doctors' perspectives, knowledge, and practices toward delirium in a large Irish hospital Hassabo, M. Mc Cluskey, P. Browne, J. Ntlholang, O. Ir J Med Sci 2024

4at
Clinical practice
Delirium management
Elderly care
Hospital doctors
Medical training

Dynamic delirium - Nursing intervention to reduce delirium in patients critically Ill, a randomized control trial Gómez Tovar, L. O. Henao Castaño, A. M. Intensive Crit Care Nurs 2024

Clinical Trial
Critical Care Nursing
Delirium
Nursing Care
Nursing Research
Nursing Theory
competing financial interests or personal relationships that could have appeared
to influence the work reported in this paper.

Delirium is more common and associated with worse outcomes in Parkinson's disease compared to older adult controls: results of two prospective longitudinal cohort studies Gerakios, F. Yarnall, A. J. Bate, G. Wright, L. Davis, D. Stephan, B. C. M. Robinson, L. Brayne, C. Stebbins, G. Taylor, J. P. Burn, D. J. Allan, L. M. Richardson, S. J. Lawson, R. A. Age Ageing 2024

Humans
Aged
Prospective Studies
*Parkinson Disease/complications/diagnosis/epidemiology
*Delirium/diagnosis/epidemiology/etiology
Longitudinal Studies
Aftercare
Patient Discharge
*Dementia/diagnosis/epidemiology/complications
Delirium
Institutionalisation
Mortality
Older people
Outcomes
Parkinson’s disease

Effectiveness of remimazolam in preventing postoperative delirium in elderly patients with proximal femoral fractures Fujimoto, D. Obata, N. Mizobuchi, S. J Anesth 2024

Elderly
Orthopedic surgery
Postoperative delirium
Proximal femur fractures
Remimazolam

Association between body mass index and delirium incidence in critically ill patients: a retrospective cohort study based on the MIMIC-IV Database Fu, J. Zhang, X. Zhang, G. Wei, C. Fu, Q. Gui, X. Ji, Y. Chen, S. BMJ Open 2024

Humans
Body Mass Index
Retrospective Studies
Incidence
*Critical Illness/epidemiology
Obesity/epidemiology
Intensive Care Units
*Delirium/complications
Adult intensive & critical care
Delirium & cognitive disorders
Obesity
Psychiatry

Structural disconnectivity in postoperative delirium: A perioperative two-center cohort study in older patients Fislage, M. Winzeck, S. Woodrow, R. Lammers-Lietz, F. Stamatakis, E. A. Correia, M. M. Preller, J. Feinkohl, I. Hendrikse, J. Pischon, T. Spies, C. D. Slooter, A. J. C. Winterer, G. Menon, D. K. Zacharias, N. Alzheimers Dement 2024

brain health
dementia delirium interface
diffusion kurtosis imaging
postoperative delirium
structural disconnectivity
white matter abnormalities

Effects of short-term preoperative intranasal dexmedetomidine plus conventional treatment on delirium following cardiac surgery in patients with sleep disorders Fang, J. Yang, J. Zhai, M. Zhang, Q. Zhang, M. Xie, Y. Perioper Med (Lond) 2024

Cognitive function
Dexmedetomidine
Preoperative intervention
Sleep disorders

The predictive value of confusion assessment method-intensive care unit and intensive care delirium screening checklist for delirium in critically ill patients in the intensive care unit: A systematic review and meta-analysis Diao, Y. Yu, X. Zhang, Q. Chen, X. Nurs Crit Care 2024

Cam‐icu
Icdsc
Icu
critically
delirium

Factors associated with disagreement between clinician app-based ultra-brief Confusion Assessment Method and reference standard delirium assessments Dhliwayo, R. Trivedi, S. Ngo, L. Fick, D. M. Inouye, S. K. Boltz, M. Leslie, D. Husser, E. Shrestha, P. Marcantonio, E. R. J Am Geriatr Soc 2024

Humans
Aged
*Delirium/epidemiology
Prospective Studies
*Mobile Applications
Confusion/diagnosis
*Dementia/complications
Reference Standards
Reproducibility of Results
Sensitivity and Specificity
accuracy
delirium
screening

Cognitive disorders in advanced Parkinson's disease: challenges in the diagnosis of delirium Daniels, C. Rodríguez-Antigüedad, J. Jentschke, E. Kulisevsky, J. Volkmann, J. Neurol Res Pract 2024

Cognition
Delirium
Parkinson’s disease
Psychosis
lecture fees from Boston Scientific, Medtronic and Newronika. Research grants
from the German Research Foundation, the German Ministry of Research and
Education, Boston Scientific and Medtronic. Lecture Honoraria from UCB, Zambon,
Abbott.

Assessment and management of delirium in a tertiary hospital-Improvements in cognitive screening and use of non-pharmacological strategies with a multidisciplinary approach Clarke, E. Newman, E. Dravid, M. Ricciardello, M. Jones, E. Caudle, K. Kilshaw, L. Hilmi, S. Flicker, L. Australas J Ageing 2024

Humans
Aged
*Delirium/diagnosis
Tertiary Care Centers
*Antipsychotic Agents
*Cognitive Dysfunction/drug therapy
Cognition
antipsychotics agents/therapeutic use
delirium/epidemiology
delirium/prevention and control
patient care team

Assessment of level of knowledge, attitude, and associated factors toward delirium among health professionals working in intensive care unit multicenter, cross-sectional study, Amhara region comprehensive specialized hospitals, Northwest Ethiopia, 2023 Ayanaw Eyayu, R. Gudayu Zeleke, T. Chekol, W. B. Yaregal Melesse, D. Enyew Ashagrie, H. Front Public Health 2024

Humans
Cross-Sectional Studies
Ethiopia
*Health Knowledge, Attitudes, Practice
Health Personnel
Intensive Care Units
Hospitals
*Delirium
attitude
delirium
intensive care
knowledge
professionals
commercial or financial relationships that could be construed as a potential
conflict of interest.

The evaluation of frequency and predictors of delirium and its short-term and long-term outcomes in hospitalized older adults' Ajmera, Y. Paul, K. Khan, M. A. Kumari, B. Kumar, N. Chatterjee, P. Dey, A. B. Chakrawarty, A. Asian J Psychiatr 2024

Humans
Aged
Middle Aged
Aged, 80 and over
*Patient Discharge
*Delirium/diagnosis/epidemiology
Activities of Daily Living
Aftercare
Hospitalization
Risk Factors
Geriatric Assessment/methods
Delirium
Geriatric psychiatry
Geriatrics
Survival
competing financial interests or personal relationships that could have appeared
to influence the work reported in this paper.

The impact of ketamine on outcomes in critically ill patients: a systematic review with meta-analysis and trial sequential analysis of randomized controlled trials Abdildin, Y. Tapinova, K. Nemerenova, A. Viderman, D. Acute Crit Care 2024

critical care
critical illness
intensive care unit
ketamine
pain management

Spanish transcultural adaptation of the 4AT score for the evaluation of delirium in the emergency department: a prospective diagnostic test accuracy study Morales-Puerto, M. Ruiz-Díaz, M. García-Mayor, S. León-Campos, Á Morales-Asencio, J. M. Canca-Sánchez, J. C. Gavira-Guerra, S. Toledo-Fernandez, C. Aranda-Gallardo, M. BMC Nurs 2024

4at
Adverse events
Delirium
Multimorbidity
Nursing
Screening tool
Validation study

Face and content validity of a mobile delirium screening tool adapted for use in the medical setting (eDIS-MED): Welcome to the machine Eeles, E. Tronstad, O. Teodorczuk, A. Flaws, D. Fraser, J. F. Dissanayaka, N. Australas J Ageing 2924

computerized adaptive testing
computers handheld
delirium
diagnosis

Social determinants of health and incident postoperative delirium: Exploring key relationships in the SAGES study Arias, F. Dufour, A. B. Jones, R. N. Alegria, M. Fong, T. G. Inouye, S. K. J Am Geriatr Soc 2024

Humans
Aged
*Emergence Delirium/complications
*Delirium/epidemiology/etiology/diagnosis
Social Determinants of Health
Prospective Studies
Retrospective Studies
Risk Factors
Postoperative Complications/epidemiology
clinical outcomes in hospitalization
delirium
private insurance

Combining biomarkers of BNIP3 L, S100B, NSE and accessible measures to prediction sepsis-associated encephalopathy: a prospective observational study Zhang, N. Xie, K. Yang, F. Wang, Y. Yang, X. Zhao, L. Curr Med Res Opin 2024

Bnip3 l
ChiCTR2200056351
Nse
Optic nerve sheath
Registered 4 February 2022 Retrospectively registered. Registered name:
establishment of a multi-modal early warning system for sepsis associated
encephalopathy
S100b
Sepsis
Sepsis-associated delirium

Association between preoperative albumin levels and postoperative delirium in geriatric hip fracture patients Wang, W. Yao, W. Tang, W. Li, Y. Lv, Q. Ding, W. Front Med (Lausanne) 2024

Pod
albumin levels
hip fracture
hypoalbuminemia
postoperative delirium
commercial or financial relationships that could be construed as a potential
conflict of interest.

Antipsychotic Use for ICU Delirium and Associated Inflammatory Markers Torbic, H. Chen, A. Lumpkin, M. Yerke, J. Mehkri, O. Abraham, S. Wang, X. Duggal, A. Scheraga, R. G. J Intensive Care Med 2024

Adult
Humans
*Antipsychotic Agents/therapeutic use
Prospective Studies
Interleukin-8
Critical Illness/therapy
Interleukin-6/therapeutic use
*Delirium/drug therapy
Intensive Care Units
antipsychotic
critically ill
delirium
inflammatory marker
interleukin

Delirium is frequently underdiagnosed among older hospitalised patients despite available information in hospital medical records Titlestad, I. Haugarvoll, K. Solvang, S. H. Norekvål, T. M. Skogseth, R. E. Andreassen, O. A. Årsland, D. Neerland, B. E. Nordrehaug, J. E. Tell, G. S. Giil, L. M. Age Ageing 2024

Humans
*Delirium/diagnosis/epidemiology/therapy
Retrospective Studies
Risk Factors
Hospitals
Medical Records
delirium
discharge diagnosis
electronic medical records
hospitalization
older people

Factors associated with delirium in a real-world acute-care setting: analysis considering the interdependence of clinical variables with the frailty syndrome Ticinesi, A. Parise, A. Delmonte, D. Coppi, C. Prati, B. Cerundolo, N. Guerra, A. Nouvenne, A. Meschi, T. Eur Geriatr Med 2024

Acute cerebral dysfunction
Cognitive impairment
Delirium
Frailty
Geriatric emergency medicine

Increased IgA-mediated responses to the gut paracellular pathway and blood-brain barrier proteins predict delirium due to hip fracture in older adults Thisayakorn, P. Thipakorn, Y. Tantavisut, S. Sirivichayakul, S. Vojdani, A. Maes, M. Front Neurol 2024

bacterial translocation
biomarkers
cytokines
inflammation
leaky gut
neuro-immune

Association of peripheral B cells and delirium: combined single-cell sequencing and Mendelian randomization analysis Tan, S. Pan, S. Wei, L. Chen, W. Pan, B. Kong, G. Chen, J. Xie, Y. Front Neurol 2024

B cell
Mendelian randomization
Pbmc
delirium
inflammation
commercial or financial relationships that could be construed as a potential
conflict of interest.

Clinical Outcomes after Multivalve Surgery in Octogenarians: Evaluating the Need for a Paradigm Shift Taghizadeh-Waghefi, A. Petrov, A. Arzt, S. Alexiou, K. Tugtekin, S. M. Matschke, K. Kappert, U. Wilbring, M. J Clin Med 2024

multivalve disease
multivalve surgery
octogenarians

Evaluating early lymphocyte-to-monocyte ratio as a predictive biomarker for delirium in older adult patients with sepsis: insights from a retrospective cohort analysis Shi, X. Yang, L. Bai, W. Jing, L. Qin, L. Front Med (Lausanne) 2024

Mimic-iv
delirium
lymphocyte-to-monocyte ratio
older adult
predictive modeling
sepsis
commercial or financial relationships that could be construed as a potential
conflict of interest.

The Association of Preoperative Diabetes With Postoperative Delirium in Older Patients Undergoing Major Orthopedic Surgery: A Prospective Matched Cohort Study Shang, Z. Jiang, Y. Fang, P. Zhu, W. Guo, J. Li, L. Liang, Y. Zhang, S. Ma, S. Mei, B. Fan, Y. Xie, Z. Shen, Q. Liu, X. Anesth Analg 2024

Postoperative delirium

diabetes

orthopedic surgery

elective surgery

3D-CAM

delirium severity

 

The role of neurohospitalism in a specialized cardiovascular hospital Serôdio, M. Magriço, M. Sobral-Pinho, A. Ventura, R. Serrazina, F. Cabral, G. Meira, B. Fernandes, M. Salavisa, M. Saraiva, M. Marto, J. P. Sá, F. Calado, S. Baptista, M. V. Eur Neurol 2024

Cardiovascular

neurology

delirium

altered mental status

AIS

 

Bringing Delirium to Light: Impact of CAM-ICU Tool to Improve Care Coordination Savino, T. Vergara, F. H. Ramos, M. D. Warzecha, D. Prof Case Manag 2024

Delirium

CCU

Early assessment

CAM-ICU

Length of Stay

Case Management

Delirium and Its Associations with Critical Care Utilizations and Outcomes at the Time of Hospital Discharge in Patients with Acute Brain Injury Raquer, A. P. Fong, C. T. Walters, A. M. Souter, M. J. Lele, A. V. Medicina (Kaunas) 2024

Humans
Aged
*Delirium/diagnosis/epidemiology/etiology
Patient Discharge
*Ischemic Stroke/complications
Critical Care
Intensive Care Units
*Brain Injuries/complications
Hospitals
acute brain injury
agitation
delirium
distress
neurocritical care
outcome
pain

Data-derived subtypes of delirium during critical illness Potter, K. M. Kennedy, J. N. Onyemekwu, C. Prendergast, N. T. Pandharipande, P. P. Ely, E. W. Seymour, C. Girard, T. D. EBioMedicine 2024

Adult
Humans
Middle Aged
Aged
*Delirium/diagnosis/etiology
Prospective Studies
Critical Illness
Interleukin-1 Receptor-Like 1 Protein
*Cognitive Dysfunction/complications
Delirium
Heterogeneity
Latent class analysis
Subtypes

Infection, delirium, and risk of dementia in patients with and without white matter disease on previous brain imaging: a population-based study Pendlebury, S. T. Luengo-Fernandez, R. Seeley, A. Downer, M. B. McColl, A. Rothwell, P. M. Lancet Healthy Longev 2024

United States
Humans
Male
Female
Aged
*Ischemic Attack, Transient/complications/diagnosis/epidemiology
*Stroke/diagnostic imaging/epidemiology/etiology
Brain/diagnostic imaging
*Leukoencephalopathies/diagnostic imaging/epidemiology/complications
*Dementia/diagnostic imaging/epidemiology/etiology
*Delirium/diagnostic imaging/epidemiology/etiology

A novel risk assessment tool for postoperative delirium in vascular surgery: The stress model (Siena posTopeRative dElirium in vaScular Surgery) Pasqui, E. de Donato, G. Brancaccio, B. Casilli, G. Ferrante, G. Palasciano, G. Vascular 2024

Vascular surgery
cardiovascular disease
delirium
risk stratification
vascular complications
of interest with respect to the research, authorship, and/or publication of this
article.

The Delphi Delirium Management Algorithms. A practical tool for clinicians, the result of a modified Delphi expert consensus approach Ottens, T. H. Hermes, C. Page, V. Oldham, M. Arora, R. Bienvenu, O. J., 3rd van den Boogaard, M. Caplan, G. Devlin, J. W. Friedrich, M. E. van Gool, W. A. Hanison, J. Hansen, H. C. Inouye, S. K. Kamholz, B. Kotfis, K. Maas, M. B. MacLullich, A. M. J. Marc Delirium (Bielef) 2024

Clinical practice algorithm
Delirium
Expert consensus
cardiac surgery
hospital medicine
intensive care

Identification of early delirium and its outcomes after cardiopulmonary bypass among adult patients with cardiovascular disease: a prospective observational study Othman, S. M. A. Xu, Q. Zhao, K. Kafi, L. Aziz, M. A. A. Indian J Thorac Cardiovasc Surg 2024

Bypass machine
Cardiopulmonary bypass-associated delirium
Perfusion-related risks
Surgical consequences
relevant to the content of this article.

Association between Preoperative Glucose Dysregulation and Delirium after Non-Cardiac Surgery Oh, A. R. Lee, D. Y. Lee, S. Lee, J. H. Yang, K. Choi, B. Park, J. J Clin Med 2024

delirium
glucose
non-cardiac surgery

Epidural vs. systemic analgesia in the Intensive Care Unit: retrospective study of patient outcomes Naser, A. Meyer, A. Ifrach, N. Dichtwald, S. Minerva Anestesiol 2024

Humans
Pain Management
Retrospective Studies
Pain
Intensive Care Units
*Analgesia, Epidural
*Delirium/epidemiology
*Pancreatitis
Length of Stay

Whole blood thiamine, intravenous thiamine supplementation and delirium occurrence in the intensive care unit: retrospective cohort analyses Mumin, M. A. McKenzie, C. A. Page, V. J. Hadfield, D. Aitken, L. M. Hanks, F. Cunningham, E. Blackwood, B. Van Dellen, E. Slooter, A. J. C. Grocott, M. P. W. McAuley, D. F. Spronk, P. E. Int J Clin Pharm 2024

Critical care
Delirium
Intensive care
Retrospective studies
Thiamine

Intraoperative Blood Pressure Management and Its Effects on Postoperative Delirium After Cardiac Surgery: A Single-Center Retrospective Cohort Study Mohr, N. L. Krannich, A. Jung, H. Hulde, N. von Dossow, V. J Cardiothorac Vasc Anesth 2024

Ioh
cardiac surgery
delirium
hemodynamic monitoring
intraoperative hypotension
stroke

Implementing pain, agitation, delirium, and sleep deprivation protocol in critically ill patients: A pilot study on pharmacological interventions Luetrakool, P. Taesotikul, S. Susantitapong, K. Suthisisang, C. Morakul, S. Sutherasan, Y. Tangsujaritvijit, V. Dilokpattanamongkol, P. Clin Transl Sci 2024

Humans
Pilot Projects
*Critical Illness/therapy
Prospective Studies
Retrospective Studies
Sleep Deprivation/drug therapy
Pain/diagnosis/drug therapy
*Delirium/drug therapy/etiology
Observational Studies as Topic

An exploratory research report on brain mineralization in postoperative delirium and cognitive decline Lammers-Lietz, F. Borchers, F. Feinkohl, I. Hetzer, S. Kanar, C. Konietschke, F. Lachmann, G. Chien, C. Spies, C. Winterer, G. Zaborszky, L. Zacharias, N. Paul, F. Eur J Neurosci 2024

anaesthesia
basal nucleus of Meynert
cholinergic system
delirium
magnetic resonance imaging
postoperative cognitive dysfunction
surgery
susceptibility weighted imaging

Delirium Severity and Physical Function in Hospitalized Persons Living With Dementia: Moderation by Age, Sex, and Race Kuzmik, A. Boltz, M. Resnick, B. McPherson, R. Rodriguez, M. Drazich, B. F. Galik, E. Alzheimer Dis Assoc Disord 2024

Male
Female
Humans
Aged
*Dementia
*Delirium
Severity of Illness Index

Effectiveness of antipsychotics for managing agitated delirium in patients with advanced cancer: a secondary analysis of a multicenter prospective observational study in Japan (Phase-R) Kurisu, K. Inada, S. Maeda, I. Nobata, H. Ogawa, A. Iwase, S. Uchida, M. Akechi, T. Amano, K. Nakajima, N. Morita, T. Sumitani, M. Yoshiuchi, K. Support Care Cancer 2024

Humans
*Antipsychotic Agents/therapeutic use
Olanzapine/therapeutic use
Japan
*Delirium/etiology/chemically induced
*Neoplasms/complications/drug therapy
Advanced cancer
Agitation
Delirium
Olanzapine
Pharmacotherapy
Richmond agitation-sedation scale

The spectrum of psychological disorders in family members of patients suffering from delirium associated with critical illness: a prospective, observational study Kotfis, K. Maj, P. Szylińska, A. Pankowiak, M. Reszka, E. Ely, E. W. Marra, A. Sci Rep 2024

Adult
Humans
Adolescent
Critical Illness/psychology
Prospective Studies
Anxiety/epidemiology/psychology
*Stress Disorders, Post-Traumatic/psychology
Intensive Care Units
Family/psychology
*Delirium/epidemiology
Depression/epidemiology/psychology
Anxiety
Delirium
Depression
Family
Intensive care unit
Pics
Pics-f
Psychological disorders

Impact of Prefracture Cognitive Impairment and Postoperative Delirium on Recovery After Hip Fracture Surgery Kamimura, T. Kobayashi, Y. Tamaki, S. Koinuma, M. J Am Med Dir Assoc 2024

Cognitive impairment
delirium
hip fracture

Development of a Prediction Model for Delirium in Hospitalized Patients with Advanced Cancer Jung, E. H. Yoo, S. H. Lee, S. W. Kang, B. Kim, Y. J. Cancer Res Treat 2024

Delirium
Neoplasms
Palliative care
Predictive model

Nurses' Knowledge and Subjective Strain in Delirium Care: Impact of a Web-based Instructional Module on Nurses Competence Jose, S. Cyriac, M. C. Dhandapani, M. Indian J Crit Care Med 2024

Delirium
Emergency wards
Hyperactive delirium
Intensive care units
Nurses
Nurses knowledge about delirium
Subjective strain
Web-based instructional module

Difficulties faced by intensive care nurses in caring for patients with delirium: A cross-sectional, multicentre study Jiang, T. Tung, T. H. Wang, Y. Zheng, X. T. Jia, L. Zhang, W. Aust Crit Care 2024

Cross-sectional study
Delirium
Difficulty
Intensive care unit
Nurses