Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Daily automated prediction of delirium risk in hospitalized patients: Model development and validation
Authors
Shaw, K. M. Shao, Y. P. Ghanta, M. Junior, V. M. Kimchi, E. Y. Houle, T. T. Akeju, O. Westover, M. B.
Year
2024
Journal
JMIR Med Inform
Abstract

BACKGROUND: Delirium is common in hospitalized patients and correlated with increased morbidity and mortality. Despite this, delirium is underdiagnosed, and many institutions do not have sufficient resources to consistently apply effective screening and prevention. OBJECTIVE: To develop a machine learning algorithm to identify patients at highest risk of delirium in the hospital each day in an automated fashion based on data available in the electronic medical record, reducing the barrier to large-scale delirium screening. METHODS: We developed and compared multiple machine learning models on a retrospective dataset of all hospitalized adult patients with recorded Confusion Assessment Method (CAM) screens at a major academic medical center from April 2nd, 2016 to January 16th 2019, comprising 23006 patients. The patient’s age, gender, and all available laboratory values, vital signs, prior CAM screens, and medication administrations were used as potential predictors. Four machine learning approaches were investigated: logistic regression with L1-regularization, multilayer perceptrons, random forests, and boosted trees. Model development used 80% of the patients; the remaining 20% were reserved for testing the final models. Lab values, vital signs, medications, gender, and age were used to predict a positive CAM screen in the next 24 hours. RESULTS: The boosted tree model achieved the greatest predictive power, with a 0.92 area under the receiver operator characteristic curve (AUROC) (95% Confidence Interval (CI) 0.913-9.22), followed by the random forest at 0.91 (95% CI 0.909-0.918), multilayer perceptron at 0.86 (95% CI 0.850-0.861), and logistic regression at 0.85 (95% CI 0.841-0.852). These AUROCs decreased to 0.78-0.82 and 0.74-0.80 when limited to patients not currently or never delirious, respectively. CONCLUSIONS: A boosted tree machine learning model was able to identify hospitalized patients at elevated risk for delirium in the next 24 hours. This may allow for automated delirium risk screening and more precise targeting of proven and investigational interventions to prevent delirium.

PMID

PMID: 39721068

Keywords

Humans *Glycocalyx/metabolism/drug effects Male *Cardiopulmonary Bypass/adverse effects Female Prospective Studies Middle Aged *Ringer’s Lactate/administration & dosage/pharmacology Aged Sodium Bicarbonate/administration & dosage/pharmacology Ringer’s Solution/administration & dosage/pharmacology Cardiac Surgical Procedures/adverse effects Cohort Studies cardiopulmonary bypass endothelial glycocalyx postoperative recovery sodium bicarbonate Ringer’s solution

Page(s)
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Total Records Found: 6499, showing 100 per page
TitleAuthorsJournalYearKeywords
Psychiatric diagnosis in the elderly referred to a consultation-liaison psychiatry service in a general geriatric hospital in Japan. Yamada K, Hosoda M, Nakashima S, Furuta K, Awata S Geriatrics & gerontology international 2012

Aged, Aged, 80 and over, Delirium, diagnosis, Depression, diagnosis, Female, Geriatrics, Hospitals, General, Humans, Japan, Male, Mental Disorders, diagnosis, Psychiatric Department, Hospital, Referral and Consultation

Screening utility of the Montreal Cognitive Assessment (MoCA): in place of--or as well as--the MMSE? Larner AJ International psychogeriatrics / IPA 2012

Adult, Aged, Aged, 80 and over, Dementia, diagnosis, Female, Humans, Male, Mass Screening, statistics & numerical data, Mental Status Schedule, statistics & numerical data, Middle Aged, Mild Cognitive Impairment, diagnosis, Neuropsychological Tests, statistics & numerical data, Psychometrics, statistics & numerical data, ROC Curve, Reproducibility of Results, Statistics as Topic, Young Adult

The sound environment in an ICU patient room--a content analysis of sound levels and patient experiences. Johansson L, Bergbom I, Waye KP, Ryherd E, Lindahl B Intensive & critical care nursing : the official journal of the British Association of Critical Care Nurses 2012

Aged, Aged, 80 and over, Attitude to Health, Delirium, prevention & control, Female, Follow-Up Studies, Health Status, Humans, Intensive Care Units, Male, Mental Recall, Middle Aged, Noise, prevention & control, Patients’ Rooms, Sweden

Prior pathology in the basal forebrain cholinergic system predisposes to inflammation-induced working memory deficits: reconciling inflammatory and cholinergic hypotheses of delirium. Field RH, Gossen A, Cunningham C The Journal of neuroscience : the official journal of the Society for Neuroscience 2012

Animals, Cholinergic Neurons, metabolism, Delirium, metabolism, Encephalitis, metabolism, Female, Memory Disorders, metabolism, Mice, Mice, Inbred C57BL, Models, Neurological, Prosencephalon, metabolism

Development and validation of PRE-DELIRIC (PREdiction of DELIRium in ICu patients) delirium prediction model for intensive care patients: observational multicentre study. van den Boogaard M, Pickkers P, Slooter AJ, Kuiper MA, Spronk PE, van der Voort PH, van der Hoeven JG, Donders R, van Achterberg T, Schoonhoven L BMJ (Clinical research ed.) 2012

APACHE, Adult, Aged, Cohort Studies, Decision Support Techniques, Delirium, diagnosis, Female, Humans, Intensive Care, methods, Intensive Care Units, Male, Medical Staff, Hospital, Middle Aged, Models, Biological, Netherlands, Prognosis, Reproducibility of Results, Risk Factors, Sensitivity and Specificity

I-SAVE study: impact of sedation, analgesia, and delirium protocols evaluated in the intensive care unit: an economic evaluation. Awissi DK, Bégin C, Moisan J, Lachaine J, Skrobik Y The Annals of pharmacotherapy 2012

APACHE, Analgesia, economics, Analgesics, administration & dosage, Clinical Protocols, Cost-Benefit Analysis, Deep Sedation, economics, Delirium, economics, Humans, Hypnotics and Sedatives, administration & dosage, Intensive Care, economics, Intensive Care Units, economics, Length of Stay, economics, Male, Middle Aged, Prospective Studies, Respiration, Artificial, economics

Systemic inflammation induces acute working memory deficits in the primed brain: relevance for delirium. Murray C, Sanderson DJ, Barkus C, Deacon RM, Rawlins JN, Bannerman DM, Cunningham C Neurobiology of aging 2012

Acute Disease, Animals, Delirium, pathology, Dementia, pathology, Disease Models, Animal, Female, Inflammation, complications, Inflammation Mediators, administration & dosage, Lipopolysaccharides, administration & dosage, Memory Disorders, pathology, Memory, Short-Term, physiology, Mice, Mice, Inbred C57BL

Poststroke delirium incidence and outcomes: validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). Mitasova A, Kostalova M, Bednarik J, Michalcakova R, Kasparek T, Balabanova P, Dusek L, Vohanka S, Ely EW Critical care medicine 2012

Adult, Aged, Aged, 80 and over, Cohort Studies, Confusion, classification, Delirium, diagnosis, Disease Progression, Female, Follow-Up Studies, Hospitals, University, Humans, Intensive Care, methods, Intensive Care Units, Male, Middle Aged, Neuropsychological Tests, Proportional Hazards Models, Prospective Studies, Reproducibility of Results, Risk Assessment, Severity of Illness Index, Statistics, Nonparametric, Stroke, diagnosis, Survival Rate

Haloperidol dosing strategies in the treatment of delirium in the critically ill. Wang EH, Mabasa VH, Loh GW, Ensom MH Neurocritical care 2012

Antipsychotic Agents, administration & dosage, Critical Illness, therapy, Delirium, drug therapy, Dose-Response Relationship, Drug, Drug Administration Schedule, Haloperidol, administration & dosage, Humans

Haloperidol prophylaxis decreases delirium incidence in elderly patients after noncardiac surgery: a randomized controlled trial*. Wang W, Li HL, Wang DX, Zhu X, Li SL, Yao GQ, Chen KS, Gu XE, Zhu SN Critical care medicine 2012

Aged, Antipsychotic Agents, therapeutic use, Delirium, epidemiology, Double-Blind Method, Female, Haloperidol, therapeutic use, Humans, Incidence, Male, Postoperative Complications, epidemiology, Prospective Studies

Patient and nurse staffing characteristics associated with high sitter use costs. Rochefort CM, Ward L, Ritchie JA, Girard N, Tamblyn RM Journal of advanced nursing 2012

Accidental Falls, prevention & control, Adult, Aged, Canada, Clinical Competence, Dangerous Behavior, Female, Health Care Costs, statistics & numerical data, Hospitalization, economics, Humans, Logistic Models, Male, Mental Disorders, economics, Middle Aged, Multivariate Analysis, Nurses’ Aides, economics, Nursing Administration Research, Nursing Staff, Hospital, supply & distribution, Patient Care, economics, Patient Safety, economics, Personnel Staffing and Scheduling, economics, Prospective Studies, Risk Factors

Three-year mortality of delirium among elderly inpatients in consultation-liaison service. Tsai MC, Weng HH, Chou SY, Tsai CS, Hung TH, Su JA General hospital psychiatry 2012

Aged, Delirium, mortality, Female, Humans, Male, Mortality, trends, Proportional Hazards Models, Referral and Consultation, Registries, Taiwan, epidemiology

The association of the kynurenine pathway of tryptophan metabolism with acute brain dysfunction during critical illness*. Adams Wilson JR, Morandi A, Girard TD, Thompson JL, Boomershine CS, Shintani AK, Ely EW, Pandharipande PP Critical care medicine 2012

Acute Disease, Aged, Brain Diseases, etiology, Critical Illness, Female, Humans, Kynurenine, blood, Male, Metabolic Networks and Pathways, Middle Aged, Prospective Studies, Tryptophan, blood

Twelve-month fall outcomes among delirium subtypes. DeCrane SK, Culp KR, Wakefield B Journal for healthcare quality : official publication of the National Association for Healthcare Quality 2012

Accidental Falls, prevention & control, Analysis of Variance, Delirium, classification, Female, Humans, Long-Term Care, statistics & numerical data, Longitudinal Studies, Male, Risk Assessment

Is health-related quality of life an independent prognostic factor for 12-month mortality and nursing home placement among elderly patients hospitalized via the emergency department? Dhaussy G, Dramé M, Jolly D, Mahmoudi R, Barbe C, Kanagaratnam L, Nazeyrollas P, Blanchard F, Novella JL, Journal of the American Medical Directors Association 2012

Aged, Aged, 80 and over, Cohort Studies, Emergency Service, Hospital, Female, France, epidemiology, Health Status, Humans, Male, Mortality, Nursing Homes, Patient Transfer, Prognosis, Prospective Studies, Quality of Life, Time Factors

Features of subsyndromal and persistent delirium. Meagher D, Adamis D, Trzepacz P, Leonard M The British journal of psychiatry : the journal of mental science 2012

Adult, Aged, Aged, 80 and over, Algorithms, Benzodiazepines, therapeutic use, Comorbidity, Delirium, diagnosis, Dementia, epidemiology, Diagnostic and Statistical Manual of Mental Disorders, Disease Progression, Female, Humans, Longitudinal Studies, Male, Middle Aged, Models, Statistical, Neuropsychological Tests, Palliative Care, Prospective Studies, Severity of Illness Index, Syndrome

Cost-effectiveness of multi-component interventions to prevent delirium in older people admitted to medical wards. Akunne A, Murthy L, Young J Age and ageing 2012

Age Factors, Aged, Aging, Computer Simulation, Cost Savings, Cost-Benefit Analysis, Delirium, diagnosis, Geriatrics, economics, Hospital Costs, Humans, Inpatients, Kaplan-Meier Estimate, Life Expectancy, Models, Economic, Odds Ratio, Patient Admission, economics, Patient Care Team, economics, Quality-Adjusted Life Years, Risk Assessment, Risk Factors, Treatment Outcome

Evaluation of delirium in elderly: a hospital-based study. Khurana V, Gambhir IS, Kishore D Geriatrics & gerontology international 2011

Aged, Aged, 80 and over, Chi-Square Distribution, Delirium, diagnosis, Female, Geriatric Assessment, Hospitalization, Humans, India, epidemiology, Male, Metabolic Diseases, complications, Middle Aged, Prevalence, Sepsis, complications

Impact of bispectral index monitoring on postoperative delirium in patients undergoing aortic surgery. Santarpino G, Fasol R, Sirch J, Ackermann B, Pfeiffer S, Fischlein T HSR proceedings in intensive care & cardiovascular anesthesia 2011

 aortic surgery

bispectral index monitoring

cerebral complications

delirium.

The importance of delirium: economic and societal costs. Leslie DL, Inouye SK Journal of the American Geriatrics Society 2011

Aged, Cost of Illness, Costs and Cost Analysis, Delirium, economics, Humans

Association cortex hypoperfusion in mild dementia with Lewy bodies: a potential indicator of cholinergic dysfunction? Fong TG, Inouye SK, Dai W, Press DZ, Alsop DC Brain imaging and behavior 2011

Aged, Alzheimer Disease, pathology, Anatomy, Cross-Sectional, Autonomic Nervous System Diseases, pathology, Cerebral Cortex, blood supply, Cerebrovascular Circulation, drug effects, Cholinesterase Inhibitors, diagnostic use, Cognition, physiology, Education, Female, Humans, Image Processing, Computer-Assisted, Lewy Body Disease, pathology, Magnetic Resonance Imaging, Male, Mental Recall, physiology, Neuropsychological Tests, Verbal Behavior

Development and validation of a brief cognitive assessment tool: the sweet 16. Fong TG, Jones RN, Rudolph JL, Yang FM, Tommet D, Habtemariam D, Marcantonio ER, Langa KM, Inouye SK Archives of internal medicine 2011

Aged, Aged, 80 and over, Cognition Disorders, diagnosis, Cohort Studies, Dementia, diagnosis, Female, Humans, Male, Neuropsychological Tests, statistics & numerical data, Questionnaires

A new model of delirium care in the acute geriatric setting: geriatric monitoring unit. Chong MS, Chan MP, Kang J, Han HC, Ding YY, Tan TL BMC geriatrics 2011

Delirium, diagnosis, Geriatrics, methods, Hospital Units, trends, Humans, Patient Care, methods, Patient Care Team, trends, Questionnaires, Time Factors

Sustaining clinical programs during difficult economic times: a case series from the Hospital Elder Life Program. SteelFisher GK, Martin LA, Dowal SL, Inouye SK Journal of the American Geriatrics Society 2011

Aged, Canada, Chronic Disease, economics, Cooperative Behavior, Cost Savings, Cost-Benefit Analysis, Decision Making, Organizational, Evidence-Based Medicine, economics, Financial Management, organization & administration, Health Services Research, Health Services for the Aged, economics, Hospitalization, economics, Humans, Interdisciplinary Communication, Long-Term Care, economics, Medicare, economics, Organizational Case Studies, Patient Care Team, economics, United States

Structured analyses of interventions to prevent delirium. Hempenius L, van Leeuwen BL, van Asselt DZ, Hoekstra HJ, Wiggers T, Slaets JP, de Bock GH International journal of geriatric psychiatry 2011

Aged, Delirium, prevention & control, Hospitalization, Humans

Hypercapnic encephalopathy syndrome: a new frontier for non-invasive ventilation? Scala R Respiratory medicine 2011

Brain Diseases, therapy, Clinical Trials as Topic, Cognition Disorders, Coma, Delirium, Humans, Hypercapnia, therapy, Intubation, Intratracheal, methods, Positive-Pressure Respiration, instrumentation, Psychomotor Agitation, Respiratory Insufficiency, therapy, Syndrome

Insulin-like growth factor I and the pathogenesis of delirium: a review of current evidence. Adamis D, Meagher D Journal of aging research 2011
Delirium

Insulin-Like growth factor I

Cognitive impairment

aging

pathology

Increased systemic perfusion pressure during cardiopulmonary bypass is associated with less early postoperative cognitive dysfunction and delirium. Siepe M, Pfeiffer T, Gieringer A, Zemann S, Benk C, Schlensak C, Beyersdorf F European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2011

Aged, Blood Pressure, physiology, Brain, blood supply, Cardiopulmonary Bypass, adverse effects, Cognition Disorders, etiology, Coronary Artery Bypass, adverse effects, Delirium, etiology, Female, Hemodynamics, physiology, Humans, Male, Middle Aged, Neuropsychological Tests, Oxygen, blood, Partial Pressure, Prospective Studies, Psychometrics

Using the Mini-Mental State Examination to screen for delirium in elderly patients with hip fracture. Ringdal GI, Ringdal K, Juliebø V, Wyller TB, Hjermstad MJ, Loge JH Dementia and geriatric cognitive disorders 2011

Aged, Aged, 80 and over, Cognition Disorders, complications, Delirium, complications, Female, Geriatric Assessment, methods, Hip Fractures, complications, Humans, Male, Mass Screening, Mental Status Schedule, Reproducibility of Results, Sensitivity and Specificity

Impact of quetiapine on resolution of individual delirium symptoms in critically ill patients with delirium: a post-hoc analysis of a double-blind, randomized, placebo-controlled study. Devlin JW, Skrobik Y, Riker RR, Hinderleider E, Roberts RJ, Fong JJ, Ruthazer R, Hill NS, Garpestad E Critical care (London, England) 2011

Adult, Antipsychotic Agents, therapeutic use, Critical Illness, Delirium, drug therapy, Dibenzothiazepines, therapeutic use, Double-Blind Method, Haloperidol, therapeutic use, Humans, Placebos, Retrospective Studies, Treatment Outcome

Cognitive and functional predictors and sequelae of postoperative delirium in elderly patients undergoing elective joint arthroplasty. Jankowski CJ, Trenerry MR, Cook DJ, Buenvenida SL, Stevens SR, Schroeder DR, Warner DO Anesthesia and analgesia 2011

Age Factors, Aged, Aged, 80 and over, Arthroplasty, Replacement, Hip, adverse effects, Arthroplasty, Replacement, Knee, adverse effects, Cognition, Cognition Disorders, complications, Delirium, diagnosis, Female, Humans, Logistic Models, Male, Minnesota, Neuropsychological Tests, Odds Ratio, Prospective Studies, Psychiatric Status Rating Scales, Risk Assessment, Risk Factors, Time Factors, Treatment Outcome

The role of inflammation in the pathogenesis of delirium and dementia in older adults: a review. Simone MJ, Tan ZS CNS neuroscience & therapeutics 2011

Aged, Aged, 80 and over, Animals, Delirium, etiology, Dementia, etiology, Humans, Inflammation, pathology, Inflammation Mediators, physiology

Review articles: postoperative delirium: acute change with long-term implications. Rudolph JL, Marcantonio ER Anesthesia and analgesia 2011

Age Factors, Attention, Cognition, Cognition Disorders, complications, Comorbidity, Delirium, diagnosis, Depression, complications, Humans, Risk Assessment, Risk Factors, Surgical Procedures, Operative, adverse effects, Time Factors, Treatment Outcome

Postoperative delirium in elderly patients after elective hip or knee arthroplasty performed under regional anesthesia. Rade MC, Yadeau JT, Ford C, Reid MC HSS journal : the musculoskeletal journal of Hospital for Special Surgery 2011

postoperative delirium

delirium

confusion assessment method

elderly, total knee arthroplasty

total hip arthroplasty

regional anesthesia

Brief report: preoperative frailty in older surgical patients is associated with early postoperative delirium. Leung JM, Tsai TL, Sands LP Anesthesia and analgesia 2011

Age Factors, Aged, Aged, 80 and over, Chi-Square Distribution, Delirium, diagnosis, Depression, complications, Female, Frail Elderly, psychology, Geriatric Assessment, Humans, Logistic Models, Male, Multivariate Analysis, Odds Ratio, Pilot Projects, Psychiatric Status Rating Scales, Risk Assessment, Risk Factors, Surgical Procedures, Operative, adverse effects

Neuroinflammation in delirium: a postmortem case-control study. Munster BC, Aronica E, Zwinderman AH, Eikelenboom P, Cunningham C, Rooij SE Rejuvenation research 2011

Aged, Aged, 80 and over, Amyloid beta-Peptides, biosynthesis, Antigens, CD, biosynthesis, Antigens, Differentiation, Myelomonocytic, biosynthesis, Autopsy, Brain, pathology, Case-Control Studies, Delirium, pathology, Female, Glial Fibrillary Acidic Protein, biosynthesis, HLA-DR Antigens, biosynthesis, Humans, Immunohistochemistry, Inflammation, pathology, Interleukin-1beta, biosynthesis, Interleukin-6, biosynthesis, Male, Middle Aged, Neurons, pathology, tau Proteins, biosynthesis

Prevalence and incidence of delirium in long-term care. McCusker J, Cole MG, Voyer P, Monette J, Champoux N, Ciampi A, Vu M, Belzile E International journal of geriatric psychiatry 2011

Aged, Aged, 80 and over, Cognition Disorders, epidemiology, Delirium, epidemiology, Dementia, epidemiology, Depressive Disorder, epidemiology, Female, Humans, Incidence, Long-Term Care, statistics & numerical data, Male, Multivariate Analysis, Prevalence, Prospective Studies, Quebec, epidemiology, Risk Factors

Reducing "iatrogenic disability" in the hospitalized frail elderly. Lafont C, Gérard S, Voisin T, Pahor M, Vellas B, The journal of nutrition, health & aging 2011

Activities of Daily Living, Aged, Delivery of Health Care, standards, Disabled Persons, Frail Elderly, Geriatric Assessment, Hospitalization, Hospitals, Humans, Iatrogenic Disease, prevention & control, Monaco, Severity of Illness Index, Terminology as Topic

Biomarkers for delirium--a review. Khan BA, Zawahiri M, Campbell NL, Boustani MA Journal of the American Geriatrics Society 2011

Aged, Biological Markers, blood, Delirium, blood, Humans

The overlap of delirium with neuropsychiatric symptoms among patients with dementia. Hölttä E, Laakkonen ML, Laurila JV, Strandberg TE, Tilvis R, Kautiainen H, Pitkälä KH The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2011

Aged, 80 and over, Behavioral Symptoms, complications, Delirium, complications, Dementia, complications, Female, Follow-Up Studies, Humans, Male, Prognosis, Psychiatric Status Rating Scales, statistics & numerical data

Risk factors for geriatric patient falls in rehabilitation hospital settings: a systematic review. Vieira ER, Freund-Heritage R, da Costa BR Clinical rehabilitation 2011

Accidental Falls, Aged, Aged, 80 and over, Female, Humans, Male, Rehabilitation Centers, standards, Risk Factors

Distress due to delirium experience. Grover S, Shah R General hospital psychiatry 2011

Adolescent, Adult, Aged, Aged, 80 and over, Delirium, complications, Female, Humans, Male, Mental Recall, Middle Aged, Questionnaires, Stress, Psychological, etiology, Young Adult

Low preoperative plasma cholinesterase activity as a risk marker of postoperative delirium in elderly patients. Cerejeira J, Batista P, Nogueira V, Firmino H, Vaz-Serra A, Mukaetova-Ladinska EB Age and ageing 2011

Acetylcholinesterase, blood, Age Factors, Aged, Aged, 80 and over, Aging, blood, Arthroplasty, Replacement, Hip, adverse effects, Bilirubin, blood, Biological Markers, blood, Butyrylcholinesterase, blood, Calcium, blood, Chi-Square Distribution, Delirium, blood, Down-Regulation, Female, Hemoglobins, metabolism, Humans, International Normalized Ratio, Male, Middle Aged, Portugal, Prospective Studies, Psychiatric Status Rating Scales, Surgical Procedures, Elective, Time Factors, Treatment Outcome

Antipsychotics in the treatment of delirium in older hospitalized adults: a systematic review. Flaherty JH, Gonzales JP, Dong B Journal of the American Geriatrics Society 2011

Aged, Antipsychotic Agents, therapeutic use, Delirium, drug therapy, Hospitalization, Humans

Hypoactive delirium after cardiac surgery as an independent risk factor for prolonged mechanical ventilation. Stransky M, Schmidt C, Ganslmeier P, Grossmann E, Haneya A, Moritz S, Raffer M, Schmid C, Graf BM, Trabold B Journal of cardiothoracic and vascular anesthesia 2011

APACHE, Adrenergic beta-Antagonists, therapeutic use, Age Factors, Aged, Anesthesia, General, Cardiac Surgical Procedures, adverse effects, Checklist, Delirium, complications, Female, Hemoglobins, metabolism, Humans, Hypokinesia, complications, Intensive Care, Length of Stay, Male, Middle Aged, Motor Activity, physiology, Pain Measurement, Postoperative Complications, etiology, Prospective Studies, Psychomotor Agitation, diagnosis, Regression Analysis, Respiration, Artificial, statistics & numerical data, Risk Factors, Treatment Outcome

Evaluation of a hospitalist-run acute care for the elderly service. Wald HL, Glasheen JJ, Guerrasio J, Youngwerth JM, Cumbler EU Journal of hospital medicine : an official publication of the Society of Hospital Medicine 2011

Academic Medical Centers, Aged, Aged, 80 and over, Critical Care, Female, Health Services for the Aged, Hospitalists, Humans, Male, Medical Audit, Retrospective Studies

Early assessment of delirium in elderly patients after hip surgery. Lee HJ, Hwang DS, Wang SK, Chee IS, Baeg S, Kim JL Psychiatry investigation 2011

Delirium

Elderly

Hip surgery

K-DRS-98

Prodromal

Delirium and sedation recognition using validated instruments: reliability of bedside intensive care unit nursing assessments from 2007 to 2010. Vasilevskis EE, Morandi A, Boehm L, Pandharipande PP, Girard TD, Jackson JC, Thompson JL, Shintani A, Gordon SM, Pun BT, Ely EW Journal of the American Geriatrics Society 2011

Aged, Conscious Sedation, Delirium, diagnosis, Female, Humans, Intensive Care Units, Male, Middle Aged, Monitoring, Physiologic, Nursing Diagnosis, Point-of-Care Systems, Prospective Studies, Reproducibility of Results

Biomarkers associated with delirium in critically ill patients and their relation with long-term subjective cognitive dysfunction; indications for different pathways governing delirium in inflamed and noninflamed patients. van den Boogaard M, Kox M, Quinn KL, van Achterberg T, van der Hoeven JG, Schoonhoven L, Pickkers P Critical care (London, England) 2011

Adult, Aged, Aged, 80 and over, Biological Markers, blood, Calcitonin, blood, Case-Control Studies, Chemokine CCL2, blood, Chi-Square Distribution, Cognition Disorders, blood, Critical Illness, psychology, Delirium, blood, Female, Humans, Hydrocortisone, blood, Inflammation, blood, Interleukin-8, blood, Interleukins, blood, Logistic Models, Male, Middle Aged, Nerve Growth Factors, blood, Protein Precursors, blood, S100 Calcium Binding Protein beta Subunit, S100 Proteins, blood, Statistics, Nonparametric

Postoperative delirium and functional decline after noncardiac surgery. Quinlan N, Rudolph JL Journal of the American Geriatrics Society 2011

Activities of Daily Living, Aged, Delirium, complications, Female, Geriatric Assessment, Humans, Male, Postoperative Complications, Prospective Studies

The Johns Hopkins Delirium Consortium: a model for collaborating across disciplines and departments for delirium prevention and treatment. Neufeld KJ, Joseph Bienvenu O, Rosenberg PB, Mears SC, Lee HB, Kamdar BB, Sieber FE, Krumm SK, Walston JD, Hager DN, Touradji P, Needham DM Journal of the American Geriatrics Society 2011

Aged, Cooperative Behavior, Delirium, prevention & control, Hospital Departments, Humans, Interdisciplinary Communication, Models, Organizational

Matching the environment to patients with delirium: lessons learned from the delirium room, a restraint-free environment for older hospitalized adults with delirium. Flaherty JH, Little MO Journal of the American Geriatrics Society 2011

Aged, Delirium, nursing, Health Facility Environment, Hospital Units, organization & administration, Hospitalization, Humans, Restraint, Physical, Retrospective Studies

Symptoms of delirium: an exploratory factor analytic study among referred patients. Jain G, Chakrabarti S, Kulhara P General hospital psychiatry 2011

Adolescent, Adult, Aged, Aged, 80 and over, Delirium, physiopathology, Factor Analysis, Statistical, Female, Humans, Male, Middle Aged, Patients, psychology, Referral and Consultation, Young Adult

Anticholinergic drugs and their effects on delirium and mortality in the elderly. Luukkanen MJ, Uusvaara J, Laurila JV, Strandberg TE, Raivio MM, Tilvis RS, Pitkälä KH Dementia and geriatric cognitive disorders extra 2011

Anticholinergic effects

Comorbidities

Delirium

Dementia

Elderly patients

Are fluctuations in motor performance a diagnostic sign of delirium? Bellelli G, Speciale S, Morghen S, Torpilliesi T, Turco R, Trabucchi M Journal of the American Medical Directors Association 2011

Aged, Aged, 80 and over, Case-Control Studies, Cognition, Delirium, diagnosis, Female, Geriatric Assessment, Humans, Male, Motor Skills, Prospective Studies, Psychomotor Performance, physiology

Delirium: a review. Gofton TE The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2011

Delirium, diagnosis, Diagnosis, Differential, Disease Progression, Humans

A critical appraisal of sedation, analgesia and delirium in neurocritical care. Teitelbaum JS, Ayoub O, Skrobik Y The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2011

Analgesia, adverse effects, Delirium, chemically induced, Humans, Hypnotics and Sedatives, Intensive Care Units, standards, Pain, drug therapy, Pain Measurement, Risk Factors

Nurses' recognition of delirium in the hospitalized older adult. Rice KL, Bennett M, Gomez M, Theall KP, Knight M, Foreman MD Clinical nurse specialist CNS 2011

Aged, Aged, 80 and over, Clinical Competence, Delirium, diagnosis, Female, Geriatric Assessment, methods, Hospitalization, Humans, Male, Nursing Assessment, methods, Nursing Evaluation Research, Nursing Staff, Hospital, standards, Observer Variation, Psychiatric Status Rating Scales, Research Personnel

Disaster strikes! Long-term care resident outcomes following a natural disaster. Cacchione PZ, Willoughby LM, Langan JC, Culp K Journal of gerontological nursing 2011

Aged, Disasters, Education, Nursing, Continuing, Humans, Inpatients, Long-Term Care, Nursing Homes, organization & administration

Characteristics associated with recurrent falls among the elderly within aged-care wards in a tertiary hospital: the effect of cognitive impairment. Chen X, Van Nguyen H, Shen Q, Chan DK Archives of gerontology and geriatrics 2011

Accidental Falls, statistics & numerical data, Age Factors, Aged, Aged, 80 and over, Female, Geriatric Assessment, methods, Humans, Incidence, Inpatients, Male, Memory, Short-Term, physiology, Mild Cognitive Impairment, complications, New South Wales, epidemiology, Prevalence, Prognosis, Prospective Studies, Risk Factors

Delirium in older adults attending adult day care and family caregiver distress. Bull MJ International journal of older people nursing 2011

Adaptation, Psychological, Adolescent, Adult, Affective Symptoms, epidemiology, Aged, Aged, 80 and over, Cross-Sectional Studies, Day Care, psychology, Delirium, epidemiology, Family, psychology, Family Health, Geriatric Nursing, methods, Health Education, methods, Humans, Middle Aged, Risk Factors

How older people nurses assess cognitive function through daily observation. Persoon A, Van der Cruijsen M, Schlattmann N, Simmes F, Van Achterberg T International journal of older people nursing 2011

Adult, Aged, Cognition, Cognition Disorders, diagnosis, Female, Geriatric Assessment, methods, Geriatric Nursing, methods, Health Knowledge, Attitudes, Practice, Humans, Male, Middle Aged, Nurse Practitioners, Nursing Assessment, methods, Nursing, Team, methods, Reproducibility of Results

Orientation strategies during delirium: are they helpful? Day J, Higgins I, Keatinge D Journal of clinical nursing 2011

Delirium, therapy, Humans

Postoperative cognitive disorders. Monk TG, Price CC Current opinion in critical care 2011

Anesthesia, Spinal, Cognition, Cognition Disorders, diagnosis, Delirium, diagnosis, Humans, Intensive Care Units, statistics & numerical data, Postoperative Complications, Preoperative Care, Psychometrics, Risk Factors, Social Class

Predictive value and validation of the NEECHAM Confusion Scale using DSM-IV criteria for delirium as gold standard. Sörensen Duppils G, Johansson I International journal of older people nursing 2011

Aged, Aged, 80 and over, Confusion, diagnosis, Delirium, diagnosis, Diagnosis-Related Groups, Female, Geriatric Assessment, methods, Geriatric Nursing, methods, Hip Fractures, epidemiology, Humans, Incidence, Male, Mass Screening, methods, Nursing Assessment, methods, Predictive Value of Tests, Reference Standards, Reproducibility of Results, Risk Factors

Pilot study of a nonpharmacological intervention for delirium superimposed on dementia. Kolanowski AM, Fick DM, Clare L, Steis M, Boustani M, Litaker M Research in gerontological nursing 2011

Aged, Cognitive Therapy, Delirium, complications, Dementia, complications, Feasibility Studies, Humans, Pilot Projects

Why still in hospital after fast-track hip and knee arthroplasty? Husted H, Lunn TH, Troelsen A, Gaarn-Larsen L, Kristensen BB, Kehlet H Acta orthopaedica 2011

Arthroplasty, Replacement, Hip, adverse effects, Arthroplasty, Replacement, Knee, adverse effects, Cohort Studies, Early Ambulation, Humans, Length of Stay, Patient Discharge, Postoperative Complications, diagnosis, Recovery of Function, Time Factors

A longitudinal study of motor subtypes in delirium: relationship with other phenomenology, etiology, medication exposure and prognosis. Meagher DJ, Leonard M, Donnelly S, Conroy M, Adamis D, Trzepacz PT Journal of psychosomatic research 2011

Adult, Aged, Aged, 80 and over, Analgesics, Opioid, adverse effects, Antipsychotic Agents, adverse effects, Cross-Sectional Studies, Delirium, diagnosis, Diagnostic and Statistical Manual of Mental Disorders, Female, Humans, Hypnotics and Sedatives, adverse effects, Longitudinal Studies, Male, Middle Aged, Motor Activity, Neuropsychological Tests, Prognosis, Prospective Studies, Severity of Illness Index

Risk factors of delirium after cardiac surgery: a systematic review. Koster S, Hensens AG, Schuurmans MJ, van der Palen J European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology 2011

Cardiovascular Diseases, nursing, Delirium, etiology, Humans, Postoperative Complications, etiology, Risk Factors

Detecting and treating delirium--key interventions you may be missing. Ghandour A, Saab R, Mehr DR The Journal of family practice 2011

Aged, Antipsychotic Agents, administration & dosage, Behavior Therapy, methods, Delirium, complications, Diagnosis, Differential, Evidence-Based Medicine, Fatal Outcome, Femoral Neck Fractures, complications, Geriatric Assessment, Heart Failure, complications, Humans, Hypertension, complications, Male, Practice Guidelines as Topic, Risk Assessment, Risk Factors, Tomography, Emission-Computed, Single-Photon, Urinary Tract Infections, complications

Neuropsychiatric disorders in hip fracture. Iolascon G, Cervone M, Gimigliano R, Di Pietro G, Gimigliano F Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases 2011

hip fracture

elderly

neuropsychiatric disorders

delirium

depression

Patients' and nurses' experiences of delirium: a review of qualitative studies. Bélanger L, Ducharme F Nursing in critical care 2011

Adult, Delirium, nursing, Geriatric Nursing, Humans, Intensive Care, Nurse-Patient Relations, Qualitative Research

The use of the Digit Span Test in screening for cognitive impairment in acute medical inpatients. Leung JL, Lee GT, Lam YH, Chan RC, Wu JY International psychogeriatrics / IPA 2011

Aged, Aged, 80 and over, Cognition Disorders, diagnosis, Delirium, diagnosis, Dementia, diagnosis, Diagnosis, Differential, Diagnostic and Statistical Manual of Mental Disorders, Female, Hong Kong, epidemiology, Humans, Inpatients, psychology, Male, Mass Screening, methods, Neuropsychological Tests, standards, Sensitivity and Specificity

An electronic tool for visual feedback to monitor the adherence to quality indicators in intensive care medicine. Kastrup M, Nolting MJ, Ahlborn R, Braun JP, Grubitzsch H, Wernecke KD, Spies C The Journal of international medical research 2011

Aged, Cardiac Surgical Procedures, mortality, Electronics, Medical, instrumentation, Feedback, Sensory, Female, Guideline Adherence, standards, Humans, Intensive Care, standards, Linear Models, Logistic Models, Male, Monitoring, Physiologic, instrumentation, Multivariate Analysis, Quality Indicators, Health Care, standards, Respiration, Artificial

Delirium risk screening and haloperidol prophylaxis program in hip fracture patients is a helpful tool in identifying high-risk patients, but does not reduce the incidence of delirium. Vochteloo AJ, Moerman S, van der Burg BL, de Boo M, de Vries MR, Niesten DD, Tuinebreijer WE, Nelissen RG, Pilot P BMC geriatrics 2011

Aged, Aged, 80 and over, Cohort Studies, Delirium, diagnosis, Female, Haloperidol, administration & dosage, Hip Fractures, diagnosis, Humans, Incidence, Male, Mass Screening, methods, Prospective Studies, Risk Factors

Cortisol, insulin, and glucose and the risk of delirium in older adults with hip fracture. Bisschop PH, de Rooij SE, Zwinderman AH, van Oosten HE, van Munster BC Journal of the American Geriatrics Society 2011

Aged, Aged, 80 and over, Biological Markers, blood, Blood Glucose, analysis, Delirium, blood, Female, Hip Fractures, complications, Humans, Hydrocortisone, blood, Insulin, blood, Male, Perioperative Period, Prospective Studies, Risk Factors

Risk factors for postoperative delirium after colorectal surgery for carcinoma. Patti R, Saitta M, Cusumano G, Termine G, Di Vita G European journal of oncology nursing : the official journal of European Oncology Nursing Society 2011

Aged, Carcinoma, surgery, Colorectal Neoplasms, surgery, Delirium, epidemiology, Female, Humans, Incidence, Male, Mental Status Schedule, Postoperative Complications, epidemiology, Prospective Studies, Risk Factors

A systematic literature review of cerebrospinal fluid biomarkers in delirium. Hall RJ, Shenkin SD, Maclullich AM Dementia and geriatric cognitive disorders 2011

Acetylcholinesterase, cerebrospinal fluid, Biological Markers, cerebrospinal fluid, Brain, metabolism, Delirium, cerebrospinal fluid, Dopamine, cerebrospinal fluid, Humans, Hydrocortisone, cerebrospinal fluid, Interleukin-8, cerebrospinal fluid, Lactic Acid, cerebrospinal fluid, Phosphopyruvate Hydratase, cerebrospinal fluid, Prognosis, Somatostatin, cerebrospinal fluid, beta-Endorphin, cerebrospinal fluid

Factors influencing the implementation of a point-of-care screening tool for delirium. Swan BA, Becker J, Brawer R, Sciamanna CN Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses 2011

Aged, Attitude of Health Personnel, Delirium, etiology, Diagnosis, Computer-Assisted, nursing, Focus Groups, Health Knowledge, Attitudes, Practice, Health Plan Implementation, Humans, Middle Aged, Orthopedic Procedures, adverse effects, Point-of-Care Systems, Postoperative Complications, nursing, United States

A questionnaire survey of critical care nurses' attitudes to delirium assessment before and after introduction of the CAM-ICU. Eastwood GM, Peck L, Bellomo R, Baldwin I, Reade MC Australian critical care : official journal of the Confederation of Australian Critical Care Nurses 2012

Aged, Clinical Nursing Research, Critical Care, Delirium, diagnosis, Female, Health Knowledge, Attitudes, Practice, Humans, Intensive Care, methods, Intensive Care Units, Male, Mass Screening, methods, Middle Aged, Needs Assessment, organization & administration, Nursing Assessment, methods, Questionnaires

Apolipoprotein E e4 allele does not increase the risk of early postoperative delirium after major surgery. Abelha FJ, Fernandes V, Botelho M, Santos P, Santos A, Machado JC, Barros H Journal of anesthesia 2012

Postoperative delirium

APOE4

Surgery

PACU

APACHE II

SAPS II

Acute confusional state of unknown cause in the elderly: a study with continuous EEG monitoring. Naeije G, Gaspard N, Depondt C, Pepersack T, Legros B Epilepsy & behavior : E&B 2012

Aged, Aged, 80 and over, Anticonvulsants, therapeutic use, Cohort Studies, Confusion, diagnosis, Electroencephalography, Female, Humans, Male, Monitoring, Physiologic, Retrospective Studies

Towards a predictive model for post-stroke delirium. Kostalova M, Bednarik J, Mitasova A, Dušek L, Michalcakova R, Kerkovsky M, Kasparek T, Jezkova M, Balabanova P, Vohanka S Brain injury : [BI] 2012

Age Factors, Aged, Bilirubin, blood, C-Reactive Protein, metabolism, Cerebral Hemorrhage, blood, Delirium, blood, Diagnostic and Statistical Manual of Mental Disorders, Female, Humans, Male, Models, Theoretical, Predictive Value of Tests, Prognosis, Prospective Studies, Risk Factors, Stroke, blood, Survival Rate, Time Factors, gamma-Glutamyltransferase, blood

Neural network functional connectivity during and after an episode of delirium. Choi SH, Lee H, Chung TS, Park KM, Jung YC, Kim SI, Kim JJ The American journal of psychiatry 2012

Aged, Case-Control Studies, Delirium, etiology, Female, Functional Neuroimaging, Gyrus Cinguli, physiopathology, Humans, Magnetic Resonance Imaging, Male, Nerve Net, physiopathology, Prefrontal Cortex, physiopathology, Severity of Illness Index

Post-stroke delirium in relation to dementia and long-term mortality. Melkas S, Laurila JV, Vataja R, Oksala N, Jokinen H, Pohjasvaara T, Leppävuori A, Kaste M, Karhunen PJ, Erkinjuntti T International journal of geriatric psychiatry 2012

Aged, Aged, 80 and over, Cohort Studies, Delirium, epidemiology, Dementia, etiology, Educational Status, Female, Finland, epidemiology, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Proportional Hazards Models, Risk Factors, Stroke, complications

Preoperative statin therapy is not associated with a decrease in the incidence of delirium after cardiac operations. Mariscalco G, Cottini M, Zanobini M, Salis S, Dominici C, Banach M, Onorati F, Piffaretti G, Covaia G, Realini M, Beghi C The Annals of thoracic surgery 2012

Age Factors, Aged, Cohort Studies, Confidence Intervals, Coronary Angiography, methods, Coronary Artery Bypass, adverse effects, Coronary Stenosis, drug therapy, Delirium, epidemiology, Female, Hospital Mortality, trends, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, administration & dosage, Incidence, Length of Stay, Male, Middle Aged, Multivariate Analysis, Odds Ratio, Postoperative Complications, epidemiology, Preoperative Care, methods, Retrospective Studies, Risk Assessment, Severity of Illness Index, Sex Factors

The effect of earplugs during the night on the onset of delirium and sleep perception: a randomized controlled trial in intensive care patients. Van Rompaey B, Elseviers MM, Van Drom W, Fromont V, Jorens PG Critical care (London, England) 2012

ICU delirium

Delirium

Earplugs

prevention

Sleep quality

NEECHAM

ICU delirium: an update. Jones SF, Pisani MA Current opinion in critical care 2012

Anesthesia, General, adverse effects, Antipsychotic Agents, therapeutic use, Critical Illness, Delirium, diagnosis, Female, Haloperidol, therapeutic use, Humans, Intensive Care, Intensive Care Units, Male, Risk Factors, Treatment Outcome

Incidence and short-term consequences of delirium in critically ill patients: A prospective observational cohort study. van den Boogaard M, Schoonhoven L, van der Hoeven JG, van Achterberg T, Pickkers P International journal of nursing studies 2012

Critical Illness, Delirium, epidemiology, Humans, Incidence, Prospective Studies

Pharmacological and nonpharmacological management of delirium in critically ill patients. Hipp DM, Ely EW Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2012

Analgesics, Non-Narcotic, therapeutic use, Antipsychotic Agents, therapeutic use, Critical Care, methods, Critical Illness, psychology, Delirium, therapy, Dexmedetomidine, therapeutic use, Humans, Respiration, Artificial, methods

The relation between atherosclerosis and the occurrence of postoperative delirium in vascular surgery patients. Pol RA, van Leeuwen BL, Reijnen MM, Zeebregts CJ Vascular medicine (London, England) 2012

Age Factors, Aged, Aged, 80 and over, Atherosclerosis, epidemiology, Cognition, Cognition Disorders, epidemiology, Comorbidity, Delirium, epidemiology, Female, Frail Elderly, Humans, Incidence, Inflammation, epidemiology, Male, Risk Assessment, Risk Factors, Smoking, epidemiology, Vascular Surgical Procedures, adverse effects

Delirium in acute stroke: a systematic review and meta-analysis. Shi Q, Presutti R, Selchen D, Saposnik G Stroke; a journal of cerebral circulation 2012

Aged, Data Interpretation, Statistical, Delirium, etiology, Female, Humans, Male, Middle Aged, Odds Ratio, Publication Bias, Reproducibility of Results, Risk, Stroke, complications, Treatment Outcome

Prospective cohort study of adverse events in older people admitted to the acute general hospital: risk factors and the impact of dementia. Watkin L, Blanchard MR, Tookman A, Sampson EL International journal of geriatric psychiatry 2012

Acute Disease, Aged, Aged, 80 and over, Cohort Studies, Delirium, epidemiology, Dementia, epidemiology, Female, Great Britain, epidemiology, Hospitals, General, statistics & numerical data, Humans, Male, Patient Safety, statistics & numerical data, Prospective Studies, Risk Factors

A longitudinal study of motor subtypes in delirium: frequency and stability during episodes. Meagher DJ, Leonard M, Donnelly S, Conroy M, Adamis D, Trzepacz PT Journal of psychosomatic research 2012

Aged, Aged, 80 and over, Cognition Disorders, epidemiology, Comorbidity, Delirium, classification, Diagnostic and Statistical Manual of Mental Disorders, Episode of Care, Female, Humans, Hyperkinesis, etiology, Hypokinesia, etiology, Intelligence Tests, Male, Middle Aged, Palliative Care, Psychiatric Status Rating Scales, Psychomotor Performance, classification, Psychophysiology, Research Design

Association between contact precautions and delirium at a tertiary care center. Day HR, Perencevich EN, Harris AD, Gruber-Baldini AL, Himelhoch SS, Brown CH, Dotter E, Morgan DJ Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 2012

Bacterial Infections, microbiology, Cross Infection, prevention & control, Delirium, epidemiology, Drug Resistance, Multiple, Bacterial, Gloves, Protective, Hospitalization, Humans, Infection Control, Male, Middle Aged, Odds Ratio, Patient Isolation, psychology, Retrospective Studies, Surgical Attire

Delirium in critically ill patients: impact on long-term health-related quality of life and cognitive functioning. van den Boogaard M, Schoonhoven L, Evers AW, van der Hoeven JG, van Achterberg T, Pickkers P Critical care medicine 2012

Aged, Aged, 80 and over, Cognition, Cognition Disorders, etiology, Critical Illness, psychology, Delirium, complications, Humans, Intensive Care Units, Middle Aged, Neuropsychological Tests, Prospective Studies, Quality of Life, psychology

Critical care nurses' role in implementing the "ABCDE bundle" into practice. Balas MC, Vasilevskis EE, Burke WJ, Boehm L, Pun BT, Olsen KM, Peitz GJ, Ely EW Critical care nurse 2012

Critical Care, methods, Delirium, nursing, Evidence-Based Nursing, organization & administration, Humans, Hypnotics and Sedatives, therapeutic use, Mobility Limitation, Nurse’s Role, Nursing Methodology Research, Nursing Staff, Hospital, organization & administration, Respiration, Artificial, nursing

A review of pharmacologic management and prevention strategies for delirium in the intensive care unit. Bledowski J, Trutia A Psychosomatics 2012

Adrenergic alpha-2 Receptor Agonists, pharmacology, Antipsychotic Agents, therapeutic use, Cholinesterase Inhibitors, pharmacology, Databases, Bibliographic, Delirium, drug therapy, Dexmedetomidine, pharmacology, Humans, Intensive Care, Intensive Care Units, statistics & numerical data, Neuroprotective Agents, therapeutic use, Prospective Studies, Randomized Controlled Trials as Topic, Treatment Outcome

The tryptophan depletion theory in delirium: not confirmed in elderly hip fracture patients. de Jonghe A, van Munster BC, Fekkes D, van Oosten HE, de Rooij SE Psychosomatics 2012

Aged, Aged, 80 and over, Analysis of Variance, Biological Markers, metabolism, Delirium, blood, Female, Hip Fractures, metabolism, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, physiology, Kynurenine, blood, Linear Models, Male, Postoperative Period, Prospective Studies, Serotonin, biosynthesis, Tryptophan, blood

Preventing delirium in older adults with recent hip fracture through multidisciplinary geriatric consultation. Deschodt M, Braes T, Flamaing J, Detroyer E, Broos P, Haentjens P, Boonen S, Milisen K Journal of the American Geriatrics Society 2012

Activities of Daily Living, Aged, Aged, 80 and over, Belgium, epidemiology, Delirium, epidemiology, Female, Geriatric Assessment, Hip Fractures, surgery, Humans, Incidence, Male, Orthopedic Procedures, adverse effects, Postoperative Complications, Prognosis, Referral and Consultation, utilization