Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Preoperative Prognostic Nutritional Index Value is Related to Postoperative Delirium in Elderly Patients After Noncardiac Surgery: A Retrospective Cohort Study
Authors
Liu, H. Dai, M. Guan, H. Gao, X. Zhou, Y. Sun, X. Zhou, J. Hu, X. Li, X. Song, Y. Han, Y. Cao, J.
Year
2021
Journal
Risk Manag Healthc Policy
Abstract

PURPOSE: Malnutrition has been considered as a risk factor for postoperative delirium (POD). The Prognostic Nutritional Index (PNI) is a validated tool for assessing nutritional status. This study aimed to investigate the association between preoperative PNI values and the occurrence of POD in elderly surgical patients. METHODS: The retrospective cohort study included 361 elderly individuals who underwent noncardiac surgery between 2018 and 2019. Perioperative data were collected from the patients’ medical records. PNI was used to evaluate preoperative nutritional status. The primary outcome was the occurrence of POD. Univariate and multivariate logistic regression analyses were used to identify key factors associated with POD and assess the relationship between PNI values and the occurrence of POD. Receiver operating characteristic (ROC) curve analysis was used to assess the predictive value of PNI for POD. RESULTS: Seventy-two (19.9%) individuals developed postoperative delirium after surgery. Compared with patients of normal nutrition status (PNI ≥ 50), mild malnutrition (PNI 45-50) did not increase the risk of POD, while patients with moderate to severe malnutrition (PNI 40-45) (odds ratio [OR], 2.92; 95% confidence interval [CI], 1.31-6.50) and serious malnutrition (PNI < 40) (OR, 3.15; 95% CI, 1.12-8.83) were more likely to develop POD. The cut-off value of PNI was 46.05 by ROC curve analysis, the area under the curve (AUC) was 0.69 (95% CI 0.62-0.77). CONCLUSION: Preoperative PNI value is related to postoperative delirium in elderly patients after noncardiac surgery.

PMID

PMC7797345

Keywords

elderly patients
noncardiac surgery
nutritional status
postoperative delirium
prognostic nutritional index

Page(s)
1-8
Issue

Search:
Total Records Found: 6194, showing 100 per page
TitleAuthorsJournalYearKeywords
Symptoms of delirium predict incident delirium in older long-term care residents. Cole MG, McCusker J, Voyer P, Monette J, Champoux N, Ciampi A, Vu M, Dyachenko A, Belzile E International psychogeriatrics / IPA 2013

Aged, Aged, 80 and over, Canada, epidemiology, Confusion, complications, Delirium, epidemiology, Dementia, complications, Female, Follow-Up Studies, Geriatric Assessment, statistics & numerical data, Humans, Incidence, Long-Term Care, Male, Predictive Value of Tests, Proportional Hazards Models, Prospective Studies, Residential Facilities, Risk Factors

Factors associated with onset of delirium among internal medicine inpatients in Spain. Díez-Manglano J, Palazón-Fraile C, Diez-Massó F, Martínez-Álvarez R, Del Corral-Beamonte E, Carreño-Borrego P, Pueyo-Tejedor P, Gomes-Martín J Nursing research 2013

Age Factors, Aged, Aged, 80 and over, Delirium, epidemiology, Female, Hospital Units, Hospitalization, statistics & numerical data, Humans, Incidence, Internal Medicine, Male, Middle Aged, Retrospective Studies, Risk Factors, Spain, Urinary Catheterization

Evaluation of the prevalence and risk factors of delirium in cardiac surgery ICU. Shadvar K, Baastani F, Mahmoodpoor A, Bilehjani E Journal of cardiovascular and thoracic research 2013
Delirium prevalence, incidence, and implications for screening in specialist palliative care inpatient settings: a systematic review. Hosie A, Davidson PM, Agar M, Sanderson CR, Phillips J Palliative medicine 2013

Delirium, diagnosis, Humans, Incidence, Mass Screening, standards, Palliative Care, methods, Prevalence, Prospective Studies

Test accuracy of short screening tests for diagnosis of delirium or cognitive impairment in an acute stroke unit setting. Lees R, Corbet S, Johnston C, Moffitt E, Shaw G, Quinn TJ Stroke; a journal of cerebral circulation 2013

Aged, Aged, 80 and over, Cognition Disorders, complications, Delirium, complications, Female, Glasgow Coma Scale, Hospital Units, Humans, Male, Mental Status Schedule, Middle Aged, Neuropsychological Tests, Predictive Value of Tests, Questionnaires, Reproducibility of Results, Sensitivity and Specificity, Stroke, complications

Subsyndromal delirium and its determinants in elderly patients hospitalized for acute medical illness. Zuliani G, Bonetti F, Magon S, Prandini S, Sioulis F, D'Amato M, Zampi E, Gasperini B, Cherubini A The journals of gerontology. Series A, Biological sciences and medical sciences 2013

Acute Disease, Aged, Aged, 80 and over, Aging, blood, Case-Control Studies, Cognition, Delirium, blood, Female, Hospitalization, Humans, Italy, epidemiology, Male, Mental Status Schedule, Oxygen, blood, Prevalence, Risk Factors

Thirty-day prevalence of delirium among very old people: a population-based study of very old people living at home and in institutions. Mathillas J, Olofsson B, Lövheim H, Gustafson Y Archives of gerontology and geriatrics 2013

Age Factors, Aged, 80 and over, psychology, Delirium, epidemiology, Dementia, epidemiology, Depression, epidemiology, Female, Finland, epidemiology, Health Status, Homes for the Aged, statistics & numerical data, Humans, Independent Living, psychology, Institutionalization, statistics & numerical data, Male, Neuropsychological Tests, Prevalence, Sweden, epidemiology

Association between leptin and delirium in elderly inpatients. Sánchez JC, Ospina JP, González MI Neuropsychiatric disease and treatment 2013
Efficacy and safety of haloperidol versus atypical antipsychotic medications in the treatment of delirium. Yoon HJ, Park KM, Choi WJ, Choi SH, Park JY, Kim JJ, Seok JH BMC psychiatry 2013

Aged, Antipsychotic Agents, adverse effects, Benzodiazepines, adverse effects, Delirium, drug therapy, Dibenzothiazepines, adverse effects, Female, Haloperidol, adverse effects, Humans, Male, Middle Aged, Prospective Studies, Risperidone, adverse effects, Treatment Outcome

Association between sedating medications and delirium in older inpatients. Rothberg MB, Herzig SJ, Pekow PS, Avrunin J, Lagu T, Lindenauer PK Journal of the American Geriatrics Society 2013

Aged, Aged, 80 and over, Antipsychotic Agents, therapeutic use, Delirium, chemically induced, Drug Therapy, Combination, Female, Follow-Up Studies, Humans, Hypnotics and Sedatives, adverse effects, Inpatients, Male, Prevalence, Psychotic Disorders, drug therapy, Retrospective Studies, Risk Factors, United States, epidemiology

Effect of intravenous haloperidol on the duration of delirium and coma in critically ill patients (Hope-ICU): a randomised, double-blind, placebo-controlled trial. Page VJ, Ely EW, Gates S, Zhao XB, Alce T, Shintani A, Jackson J, Perkins GD, McAuley DF The Lancet. Respiratory medicine 2013
Educational interventions to improve recognition of delirium: a systematic review. Yanamadala M, Wieland D, Heflin MT Journal of the American Geriatrics Society 2013

Aged, Delirium, diagnosis, Health Personnel, education, Humans

Temperature variability during delirium in ICU patients: an observational study. van der Kooi AW, Kappen TH, Raijmakers RJ, Zaal IJ, Slooter AJ PloS one 2013
Automatic delirium prediction system in a Korean surgical intensive care unit. Oh SH, Park EJ, Jin Y, Piao J, Lee SM Nursing in critical care 2014
Neuropathogenesis of delirium: review of current etiologic theories and common pathways. Maldonado JR The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2013

Acetylcholine, metabolism, Aging, Brain, immunology, Chronobiology Disorders, complications, Delirium, etiology, Dopamine, metabolism, Humans, Inflammation, metabolism, Neural Pathways, physiopathology, Oxidative Stress, physiology

A longitudinal study of delirium phenomenology indicates widespread neural dysfunction. Leonard M, Adamis D, Saunders J, Trzepacz P, Meagher D Palliative & supportive care 2013
The pharmacologic treatment of intensive care unit delirium: a systematic review. Bathula M, Gonzales JP The Annals of pharmacotherapy 2013

Antipsychotic Agents, therapeutic use, Delirium, drug therapy, Humans, Intensive Care Units

Outcome and quality of life in patients with postoperative delirium during an ICU stay following major surgery. Abelha FJ, Luís C, Veiga D, Parente D, Fernandes V, Santos P, Botelho M, Santos A, Santos C Critical care (London, England) 2013
Preoperative cerebrospinal fluid cytokine levels and the risk of postoperative delirium in elderly hip fracture patients. Westhoff D, Witlox J, Koenderman L, Kalisvaart KJ, de Jonghe JF, van Stijn MF, Houdijk AP, Hoogland IC, Maclullich AM, van Westerloo DJ, van de Beek D, Eikelenboom P, van Gool WA Journal of neuroinflammation 2013

Aged, Aged, 80 and over, Biological Markers, cerebrospinal fluid, Cytokines, cerebrospinal fluid, Delirium, cerebrospinal fluid, Double-Blind Method, Female, Hip Fractures, cerebrospinal fluid, Humans, Male, Postoperative Complications, cerebrospinal fluid, Randomized Controlled Trials as Topic, Risk Factors

Delirium in Australian hospitals: a prospective study. Travers C, Byrne GJ, Pachana NA, Klein K, Gray L Current gerontology and geriatrics research 2013
Confusion assessment method: a systematic review and meta-analysis of diagnostic accuracy. Shi Q, Warren L, Saposnik G, Macdermid JC Neuropsychiatric disease and treatment 2013
Long-term cognitive impairment after critical illness. Pandharipande PP, Girard TD, Jackson JC, Morandi A, Thompson JL, Pun BT, Brummel NE, Hughes CG, Vasilevskis EE, Shintani AK, Moons KG, Geevarghese SK, Canonico A, Hopkins RO, Bernard GR, Dittus RS, Ely EW, The New England journal of medicine 2013

Aged, Cognition Disorders, etiology, Critical Illness, psychology, Delirium, complications, Executive Function, Female, Humans, Intensive Care Units, Linear Models, Male, Middle Aged, Prospective Studies, Respiratory Insufficiency, complications, Shock, complications

Incidence and risk factors of early delirium after cardiac surgery. Norkienė I, Ringaitienė D, Kuzminskaitė V, Šipylaitė J BioMed research international 2013

Aged, Cardiac Surgical Procedures, adverse effects, Delirium, epidemiology, Female, Humans, Intensive Care Units, Length of Stay, Male, Middle Aged, Postoperative Complications, epidemiology, Respiration, Artificial, adverse effects, Risk Factors

Intracerebral hemorrhage and delirium symptoms. Length of stay, function, and quality of life in a 114-patient cohort. Naidech AM, Beaumont JL, Rosenberg NF, Maas MB, Kosteva AR, Ault ML, Cella D, Ely EW American journal of respiratory and critical care medicine 2013

Aged, Cerebral Hemorrhage, complications, Delirium, diagnosis, Female, Humans, Intensive Care Units, standards, Internet, Kaplan-Meier Estimate, Length of Stay, Logistic Models, Male, Middle Aged, Outcome Assessment (Health Care), Prognosis, Proportional Hazards Models, Prospective Studies, Quality of Life, Questionnaires, Sickness Impact Profile

High serum interleukin-6 level is associated with increased risk of delirium in elderly patients after noncardiac surgery: a prospective cohort study. Liu P, Li YW, Wang XS, Zou X, Zhang DZ, Wang DX, Li SZ Chinese medical journal 2013

Aged, Cohort Studies, Delirium, etiology, Female, Humans, Interleukin-6, blood, Male, Middle Aged, Postoperative Complications, blood, Prospective Studies, Risk

Contextual issues influencing implementation and outcomes associated with an integrated approach to managing pain, agitation, and delirium in adult ICUs. Carrothers KM, Barr J, Spurlock B, Ridgely MS, Damberg CL, Ely EW Critical care medicine 2013

Delirium, prevention & control, Delivery of Health Care, Integrated, organization & administration, Early Ambulation, Health Care Surveys, Hospitals, Community, Humans, Intensive Care, organization & administration, Intensive Care Units, Interdisciplinary Communication, Outcome Assessment (Health Care), Pain Management, Pilot Projects, Practice Guidelines as Topic, Program Development, Psychomotor Agitation, prevention & control, San Francisco, Ventilator Weaning

Who is at risk of long hospital stay among patients admitted to geriatric acute care unit? Results from a prospective cohort study. Beauchet O, Launay C, de Decker L, Fantino B, Kabeshova A, Annweiler C The journal of nutrition, health & aging 2013

Aged, Aged, 80 and over, Critical Care, Delirium, complications, Female, France, Geriatrics, Hospital Units, Humans, Kaplan-Meier Estimate, Length of Stay, Linear Models, Male, Odds Ratio, Prospective Studies, Risk Factors, Sex Factors, Vitamin D Deficiency, blood

Implementing the awakening and breathing coordination, delirium monitoring/management, and early exercise/mobility bundle into everyday care: opportunities, challenges, and lessons learned for implementing the ICU Pain, Agitation, and Delirium Guidelines. Balas MC, Burke WJ, Gannon D, Cohen MZ, Colburn L, Bevil C, Franz D, Olsen KM, Ely EW, Vasilevskis EE Critical care medicine 2013

Academic Medical Centers, Delirium, prevention & control, Early Ambulation, methods, Evidence-Based Medicine, Focus Groups, Health Care Surveys, Health Knowledge, Attitudes, Practice, Humans, Intensive Care, methods, Intensive Care Units, Interdisciplinary Communication, Midwestern United States, Monitoring, Physiologic, methods, Practice Guidelines as Topic, Program Development, Prospective Studies, Psychomotor Agitation, prevention & control, Respiration, Artificial, Ventilator Weaning

Relationship between cognitive and non-cognitive symptoms of delirium. Rajlakshmi AK, Mattoo SK, Grover S Asian journal of psychiatry 2013

Adult, Aged, Aged, 80 and over, Attention, physiology, Cognition Disorders, epidemiology, Comprehension, physiology, Cross-Sectional Studies, Delirium, epidemiology, Female, Humans, Male, Middle Aged, Motor Activity, physiology, Neuropsychological Tests, Prospective Studies, Psychiatric Status Rating Scales, Severity of Illness Index, Young Adult

Validation of the Swedish version of the Nursing Delirium Screening Scale used in patients 70 years and older undergoing cardiac surgery. Lingehall HC, Smulter N, Engström KG, Gustafson Y, Olofsson B Journal of clinical nursing 2013

Aged, Aged, 80 and over, Delirium, diagnosis, Female, Humans, Male, Nursing Assessment, Sweden, Thoracic Surgery

Perioperative psycho-educational intervention can reduce postoperative delirium in patients after cardiac surgery: a pilot study. Lee J, Jung J, Noh JS, Yoo S, Hong YS International journal of psychiatry in medicine 2013

Adult, Aged, Cross-Sectional Studies, Delirium, epidemiology, Empathy, Female, Heart Diseases, psychology, Humans, Intensive Care Units, Internship and Residency, Male, Middle Aged, Patient Education as Topic, methods, Perioperative Care, Physician-Patient Relations, Postoperative Complications, epidemiology, Retrospective Studies, Thoracic Surgery, education, Treatment Outcome

Effectiveness of a multi-component intervention to reduce delirium incidence in elderly care wards. Holt R, Young J, Heseltine D Age and ageing 2013

Activities of Daily Living, Age Factors, Aged, Aged, 80 and over, Aging, Delirium, diagnosis, Emergencies, England, epidemiology, Female, Geriatric Assessment, Geriatrics, Hospital Mortality, Hospital Units, Hospitals, General, Humans, Incidence, Length of Stay, Male, Patient Admission, Patient Discharge, Predictive Value of Tests, Prognosis, Psychiatric Status Rating Scales, Risk Factors, Severity of Illness Index, Time Factors

White-matter hyperintensities predict delirium after cardiac surgery. Hatano Y, Narumoto J, Shibata K, Matsuoka T, Taniguchi S, Hata Y, Yamada K, Yaku H, Fukui K The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2013
Developing and implementing an integrated delirium prevention system of care: a theory driven, participatory research study. Godfrey M, Smith J, Green J, Cheater F, Inouye SK, Young JB BMC health services research 2013

Aged, Community-Based Participatory Research, methods, Delirium, prevention & control, Delivery of Health Care, Integrated, organization & administration, Education, England, Focus Groups, Health Knowledge, Attitudes, Practice, Humans, Interviews as Topic, Models, Organizational, Program Development, State Medicine, organization & administration

ICU early mobilization: from recommendation to implementation at three medical centers. Engel HJ, Needham DM, Morris PE, Gropper MA Critical care medicine 2013

Academic Medical Centers, Baltimore, Early Ambulation, standards, Humans, Intensive Care, methods, Intensive Care Units, North Carolina, Program Development, Quality Improvement, Retrospective Studies, San Francisco

A greater analgesia, sedation, delirium order set quality score is associated with a decreased duration of mechanical ventilation in cardiovascular surgery patients. Dale CR, Bryson CL, Fan VS, Maynard C, Yanez ND, Treggiari MM Critical care medicine 2013

Aged, Analgesia, methods, Cardiovascular Surgical Procedures, Clinical Protocols, Critical Illness, Delirium, diagnosis, Female, Humans, Hypnotics and Sedatives, administration & dosage, Intensive Care Units, Male, Middle Aged, Pain, diagnosis, Quality Indicators, Health Care, Quality of Health Care, organization & administration, Respiration, Artificial, methods, Retrospective Studies

Onset, risk factors, and impact of delirium in patients with traumatic spinal cord injury. Cheung A, Thorogood NP, Noonan VK, Zhong Y, Fisher CG, Dvorak MF, Street J Journal of neurotrauma 2013

Aged, Cohort Studies, Delirium, epidemiology, Female, Humans, Length of Stay, Logistic Models, Male, Middle Aged, Retrospective Studies, Risk Factors, Spinal Cord Injuries, complications

The pain, agitation, and delirium care bundle: synergistic benefits of implementing the 2013 Pain, Agitation, and Delirium Guidelines in an integrated and interdisciplinary fashion. Barr J, Pandharipande PP Critical care medicine 2013

Adult, Critical Illness, Delirium, drug therapy, Delivery of Health Care, Integrated, Humans, Intensive Care, methods, Intensive Care Units, Interdisciplinary Communication, Outcome Assessment (Health Care), Pain Management, Practice Guidelines as Topic, Psychomotor Agitation, drug therapy

Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the Intensive Care Unit: executive summary. Barr J, Fraser GL, Puntillo K, Ely EW, Gélinas C, Dasta JF, Davidson JE, Devlin JW, Kress JP, Joffe AM, Coursin DB, Herr DL, Tung A, Robinson BR, Fontaine DK, Ramsay MA, Riker RR, Sessler CN, Pun B, Skrobik Y, Jaeschke R, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 2013

Adult, Delirium, diagnosis, Disease Management, Humans, Intensive Care Units, standards, Pain, diagnosis, Pain Management, methods, Psychomotor Agitation, diagnosis

Perceptions of nurses and physicians of their communication at night about intensive care patients' pain, agitation, and delirium. Al-Qadheeb NS, Hoffmeister J, Roberts R, Shanahan K, Garpestad E, Devlin JW American journal of critical care : an official publication, American Association of Critical-Care Nurses 2013

Academic Medical Centers, Analysis of Variance, Communication, Data Collection, Delirium, Factor Analysis, Statistical, Female, Humans, Hypnotics and Sedatives, administration & dosage, Intensive Care Units, organization & administration, Male, Night Care, organization & administration, Pain, Physician-Nurse Relations, Psychomotor Agitation

Delirium in the acute phase after stroke and the role of the apolipoprotein E gene. Oldenbeuving AW, de Kort PL, Kappelle LJ, van Duijn CM, Roks G The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2013
Consensus and variations in opinions on delirium care: a survey of European delirium specialists. Morandi A, Davis D, Taylor JK, Bellelli G, Olofsson B, Kreisel S, Teodorczuk A, Kamholz B, Hasemann W, Young J, Agar M, de Rooij SE, Meagher D, Trabucchi M, MacLullich AM International psychogeriatrics / IPA 2013

Data Collection, Delirium, therapy, Europe, epidemiology, Geriatric Psychiatry, methods, Humans, Practice Guidelines as Topic, standards, Questionnaires

Effect of sedation level on the prevalence of delirium when assessed with CAM-ICU and ICDSC. Haenggi M, Blum S, Brechbuehl R, Brunello A, Jakob SM, Takala J Intensive care medicine 2013

Aged, Consciousness, drug effects, Delirium, diagnosis, Female, Humans, Hypnotics and Sedatives, administration & dosage, Intensive Care, methods, Intensive Care Units, Male, Mass Screening, methods, Middle Aged, Prevalence, Psychiatric Status Rating Scales

Delirium outcomes in a randomized trial of blood transfusion thresholds in hospitalized older adults with hip fracture. Gruber-Baldini AL, Marcantonio E, Orwig D, Magaziner J, Terrin M, Barr E, Brown JP, Paris B, Zagorin A, Roffey DM, Zakriya K, Blute MR, Hebel JR, Carson JL Journal of the American Geriatrics Society 2013

Aged, Aged, 80 and over, Blood Transfusion, methods, Delirium, blood, Erythrocyte Transfusion, methods, Female, Hemoglobinometry, Hip Fractures, blood, Hospitalization, Humans, Male, Mental Status Schedule, Neuropsychological Tests, Risk Factors

A pilot study to test the feasibility of a nonpharmacologic intervention for the prevention of delirium in the medical intensive care unit. Foster J, Kelly M Clinical nurse specialist CNS 2013

Delirium, prevention & control, Feasibility Studies, Female, Humans, Intensive Care Units, Male, Pilot Projects, Prospective Studies, Southwestern United States

Delirium superimposed on dementia is associated with prolonged length of stay and poor outcomes in hospitalized older adults. Fick DM, Steis MR, Waller JL, Inouye SK Journal of hospital medicine : an official publication of the Society of Hospital Medicine 2013

Aged, Aged, 80 and over, Cohort Studies, Delirium, diagnosis, Dementia, diagnosis, Female, Follow-Up Studies, Hospitalization, trends, Humans, Length of Stay, trends, Male, Prospective Studies, Risk Factors, Treatment Outcome

The AWOL tool: derivation and validation of a delirium prediction rule. Douglas VC, Hessler CS, Dhaliwal G, Betjemann JP, Fukuda KA, Alameddine LR, Lucatorto R, Johnston SC, Josephson SA Journal of hospital medicine : an official publication of the Society of Hospital Medicine 2013

Aged, Aged, 80 and over, Cohort Studies, Delirium, diagnosis, Female, Follow-Up Studies, Humans, Male, Middle Aged, Predictive Value of Tests, Prospective Studies, Psychiatric Status Rating Scales, standards, Risk Factors

The epidemiology of delirium: challenges and opportunities for population studies. Davis DH, Kreisel SH, Muniz Terrera G, Hall AJ, Morandi A, Boustani M, Neufeld KJ, Lee HB, Maclullich AM, Brayne C The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2013

Cognition Disorders, epidemiology, Data Collection, methods, Delirium, diagnosis, Disease Progression, Humans, Research Design

Delirium during acute illness in nursing home residents. Boockvar K, Signor D, Ramaswamy R, Hung W Journal of the American Medical Directors Association 2013

Acute Disease, Aged, Cognition Disorders, epidemiology, Delirium, epidemiology, Female, Geriatric Assessment, Humans, Incidence, Male, New York City, epidemiology, Nursing Homes, Prospective Studies, Risk Factors

Antipsychotic prescribing patterns, and the factors and outcomes associated with their use, among patients requiring prolonged mechanical ventilation in the long-term acute care hospital setting. Al-Qadheeb NS, O'Connor HH, White AC, Neidhardt A, Albizati M, Joseph B, Roberts RJ, Ruthazer RR, Devlin JW The Annals of pharmacotherapy 2013

Adult, Aged, Aged, 80 and over, Antipsychotic Agents, administration & dosage, Benzodiazepines, administration & dosage, Caregivers, Cohort Studies, Delirium, diagnosis, Dibenzothiazepines, administration & dosage, Drug Administration Schedule, Female, Hospitals, Chronic Disease, Humans, Male, Massachusetts, Medical Records, Middle Aged, Patient Participation, Physician’s Practice Patterns, Psychiatric Status Rating Scales, Respiration, Artificial, psychology, Retrospective Studies

Pre-existing cerebral infarcts as a risk factor for delirium after coronary artery bypass graft surgery. Otomo S, Maekawa K, Goto T, Baba T, Yoshitake A Interactive cardiovascular and thoracic surgery 2013

Aortic Diseases, complications, Atherosclerosis, complications, Cerebral Angiography, Cerebral Infarction, complications, Cognition, Cognition Disorders, complications, Coronary Artery Bypass, adverse effects, Delirium, diagnosis, Female, Humans, Magnetic Resonance Angiography, Male, Middle Aged, Neuropsychological Tests, Prospective Studies, Risk Factors, Surgical Procedures, Elective, Ultrasonography, Interventional

Delirium after cardiac surgery: incidence and risk factors. Smulter N, Lingehall HC, Gustafson Y, Olofsson B, Engström KG Interactive cardiovascular and thoracic surgery 2013

Age Factors, Aged, Aged, 80 and over, Cardiac Surgical Procedures, adverse effects, Delirium, diagnosis, Female, Humans, Incidence, Logistic Models, Male, Multivariate Analysis, Odds Ratio, Psychiatric Status Rating Scales, Risk Factors, Sweden, epidemiology

Predictive factors for agitation severity of hyperactive delirium in terminally ill cancer patients in a general hospital using ordered logistic regression analysis. Kanbayashi Y, Hatano Y, Hata Y, Morita T, Fukui K, Hosokawa T Journal of palliative medicine 2013

Aged, Anti-Bacterial Agents, therapeutic use, Anti-Inflammatory Agents, Non-Steroidal, therapeutic use, Bilirubin, analysis, Delirium, epidemiology, Female, Hematologic Neoplasms, complications, Hospitals, General, Humans, Japan, epidemiology, Logistic Models, Male, Middle Aged, Predictive Value of Tests, Prevalence, Psychomotor Agitation, epidemiology, Risk Factors, Severity of Illness Index, Sex Factors, Terminally Ill

Outcomes of a Geriatric Liaison Intervention to Prevent the Development of Postoperative Delirium in Frail Elderly Cancer Patients: Report on a Multicentre, Randomized, Controlled Trial. Hempenius L, Slaets JP, van Asselt D, de Bock GH, Wiggers T, van Leeuwen BL PloS one 2013
Care in specialist medical and mental health unit compared with standard care for older people with cognitive impairment admitted to general hospital: randomised controlled trial (NIHR TEAM trial). Goldberg SE, Bradshaw LE, Kearney FC, Russell C, Whittamore KH, Foster PE, Mamza J, Gladman JR, Jones RG, Lewis SA, Porock D, Harwood RH, BMJ (Clinical research ed.) 2013

Aged, Aged, 80 and over, Cognition Disorders, therapy, Delirium, therapy, Dementia, therapy, Female, Great Britain, Hospitalization, Hospitals, General, Humans, Length of Stay, Male, Neuropsychological Tests, Outcome Assessment (Health Care), Patient Readmission, Psychiatric Department, Hospital, Quality of Health Care, Quality of Life

At the extreme end of the psychoneuroimmunological spectrum: delirium as a maladaptive sickness behaviour response. Cunningham C, Maclullich AM Brain, behavior, and immunity 2013

Adaptation, Physiological, physiology, Animals, Anxiety, complications, Brain, physiopathology, Cognition, physiology, Delirium, etiology, Depression, complications, Humans, Illness Behavior, physiology, Inflammation, complications, Neurodegenerative Diseases, complications, Stress, Physiological, physiology

The stress response to surgery and postoperative delirium: evidence of hypothalamic-pituitary-adrenal axis hyperresponsiveness and decreased suppression of the GH/IGF-1 Axis. Cerejeira J, Batista P, Nogueira V, Vaz-Serra A, Mukaetova-Ladinska EB Journal of geriatric psychiatry and neurology 2013

Aged, Aged, 80 and over, Anesthesia, Arthroplasty, Replacement, Hip, adverse effects, Cognition, physiology, Data Interpretation, Statistical, Delirium, etiology, Female, Growth Hormone, blood, Humans, Hydrocortisone, blood, Hypothalamo-Hypophyseal System, physiopathology, Immune System, physiology, Inflammation Mediators, blood, Insulin-Like Growth Factor I, physiology, Male, Middle Aged, Neurosecretory Systems, physiology, Perioperative Care, Pituitary-Adrenal System, physiopathology, Postoperative Complications, etiology, Postoperative Period, Stress, Physiological, physiology

Do earplugs and eye masks affect sleep and delirium outcomes in the critically ill? Alway A, Halm MA, Shilhanek M, St Pierre J American journal of critical care : an official publication, American Association of Critical-Care Nurses 2013

Critical Illness, Delirium, prevention & control, Ear Protective Devices, Humans, Intensive Care Units, Masks, Self Report, Sleep Disorders, prevention & control

Outcomes of early delirium diagnosis after general anesthesia in the elderly. Neufeld KJ, Leoutsakos JM, Sieber FE, Wanamaker BL, Gibson Chambers JJ, Rao V, Schretlen DJ, Needham DM Anesthesia and analgesia 2013

Activities of Daily Living, Aftercare, Age Factors, Aged, Aged, 80 and over, Anesthesia Recovery Period, Anesthesia, General, adverse effects, Baltimore, epidemiology, Cognition, Cognition Disorders, diagnosis, Delirium, diagnosis, Early Diagnosis, Female, Humans, Institutionalization, Linear Models, Logistic Models, Male, Multivariate Analysis, Neuropsychological Tests, Patient Discharge, Patient Transfer, Predictive Value of Tests, Prevalence, Prognosis, Prospective Studies, Psychiatric Status Rating Scales, Recovery Room, Risk Factors, Time Factors

An enhanced exercise and cognitive programme does not appear to reduce incident delirium in hospitalised patients: a randomised controlled trial. Jeffs KJ, Berlowitz DJ, Grant S, Lawlor V, Graco M, de Morton NA, Savige JA, Lim WK BMJ open 2013
BIS-guided anesthesia decreases postoperative delirium and cognitive decline. Chan MT, Cheng BC, Lee TM, Gin T, Journal of neurosurgical anesthesiology 2013

Aged, Anesthesia, General, adverse effects, Asian Continental Ancestry Group, Cognition Disorders, etiology, Color Perception, physiology, Consciousness Monitors, Delirium, etiology, Female, Humans, Male, Neuropsychological Tests, Postoperative Complications, prevention & control, Prospective Studies, Risk Factors, Treatment Outcome, Verbal Behavior, Verbal Learning

Investigating polypharmacy and drug burden index in hospitalised older people. Best O, Gnjidic D, Hilmer SN, Naganathan V, McLachlan AJ Internal medicine journal 2013

Age Factors, Aged, Aged, 80 and over, Cholinergic Antagonists, administration & dosage, Cohort Studies, Delirium, chemically induced, Female, Hospitalization, trends, Humans, Hypnotics and Sedatives, administration & dosage, Male, New South Wales, epidemiology, Polypharmacy, Retrospective Studies

An analytical framework for delirium research in palliative care settings: integrated epidemiologic, clinician-researcher, and knowledge user perspectives. Lawlor PG, Davis DH, Ansari M, Hosie A, Kanji S, Momoli F, Bush SH, Watanabe S, Currow DC, Gagnon B, Agar M, Bruera E, Meagher DJ, de Rooij SE, Adamis D, Caraceni A, Marchington K, Stewart DJ Journal of pain and symptom management 2014
Practical assessment of delirium in palliative care. Leonard MM, Nekolaichuk C, Meagher DJ, Barnes C, Gaudreau JD, Watanabe S, Agar M, Bush SH, Lawlor PG Journal of pain and symptom management 2014
Delirium diagnostic and classification challenges in palliative care: subsyndromal delirium, comorbid delirium-dementia, and psychomotor subtypes. Leonard MM, Agar M, Spiller JA, Davis B, Mohamad MM, Meagher DJ, Lawlor PG Journal of pain and symptom management 2014
End-of-life delirium: issues regarding recognition, optimal management, and the role of sedation in the dying phase. Bush SH, Leonard MM, Agar M, Spiller JA, Hosie A, Wright DK, Meagher DJ, Currow DC, Bruera E, Lawlor PG Journal of pain and symptom management 2014
A comparison of the revised Delirium Rating Scale (DRS-R98) and the Memorial Delirium Assessment Scale (MDAS) in a palliative care cohort with DSM-IV delirium. O'Sullivan R, Meagher D, Leonard M, Watne LO, Hall RJ, Maclullich AM, Trzepacz P, Adamis D Palliative & supportive care 2015
The descriptive epidemiology of delirium symptoms in a large population-based cohort study: results from the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS). Davis DH, Barnes LE, Stephan BC, MacLullich AM, Meagher D, Copeland J, Matthews FE, Brayne C, BMC geriatrics 2014
Phenomenological and biological correlates of improved cognitive function in hospitalized elderly medical inpatients. Adamis D, Meagher D, Treloar A, Dunne C, Larvin M, Martin FC, Macdonald AJ Archives of gerontology and geriatrics 2014
Delirium during psychiatric admission increases mortality in psychiatric patients during and after hospitalization. A nationwide study from 1995 through 2012. Lundberg AS, Gustafsson LN, Meagher D, Munk-Jørgensen P Journal of psychosomatic research 2014
The CareWell in Hospital program to improve the quality of care for frail elderly inpatients: results of a before-after study with focus on surgical patients. Bakker FC, Persoon A, Bredie SJ, van Haren-Willems J, Leferink VJ, Noyez L, Schoon Y, Olde Rikkert MG American journal of surgery 2014
Outcomes of an innovative model of acute delirium care: the Geriatric Monitoring Unit (GMU). Chong MS, Chan M, Tay L, Ding YY Clinical interventions in aging 2014
Delirium in elderly people--authors'reply. Inouye SK, Westendorp RG, Saczynski JS, Kimchi EY, Cleinman AA Lancet 2014

Delirium, diagnosis, Humans

Delirium risk prediction, healthcare use and mortality of elderly adults in the emergency department. Kennedy M, Enander RA, Tadiri SP, Wolfe RE, Shapiro NI, Marcantonio ER Journal of the American Geriatrics Society 2014

Aged, Aged, 80 and over, Delirium, complications, Delivery of Health Care, utilization, Emergency Service, Hospital, Female, Follow-Up Studies, Geriatric Assessment, methods, Humans, Incidence, Length of Stay, trends, Male, Massachusetts, epidemiology, Mental Status Schedule, Prospective Studies, Risk Factors, Stroke, complications, Survival Rate, trends

Preoperative cerebrospinal fluid β-Amyloid/Tau ratio and postoperative delirium. Xie Z, Swain CA, Ward SA, Zheng H, Dong Y, Sunder N, Burke DW, Escobar D, Zhang Y, Marcantonio ER Annals of clinical and translational neurology 2014
Calibration and validation of an innovative approach for estimating general cognitive performance. Gross AL, Jones RN, Fong TG, Tommet D, Inouye SK Neuroepidemiology 2014
The modified Hospital Elder Life Program: adapting a complex intervention for feasibility and scalability in a surgical setting. Chen CC, Saczynski J, Inouye SK Journal of gerontological nursing 2014

Aged, Evidence-Based Practice, Feasibility Studies, Health Services for the Aged, organization & administration, Hospitals, Humans, Surgical Procedures, Operative

NICE to HELP: operationalizing National Institute for Health and Clinical Excellence guidelines to improve clinical practice. Yue J, Tabloski P, Dowal SL, Puelle MR, Nandan R, Inouye SK Journal of the American Geriatrics Society 2014

Aged, 80 and over, Delirium, diagnosis, Delivery of Health Care, standards, Geriatrics, standards, Great Britain, epidemiology, Humans, Practice Guidelines as Topic, Prevalence

Delirium diagnosis methodology used in research: a survey-based study. Neufeld KJ, Nelliot A, Inouye SK, Ely EW, Bienvenu OJ, Lee HB, Needham DM The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2014
Systemic inflammation impairs attention and cognitive flexibility but not associative learning in aged rats: possible implications for delirium. Culley DJ, Snayd M, Baxter MG, Xie Z, Lee IH, Rudolph J, Inouye SK, Marcantonio ER, Crosby G Frontiers in aging neuroscience 2014
The Prevention of Delirium and Complications Associated with Surgical Treatments (PODCAST) study: protocol for an international multicentre randomised controlled trial. Avidan MS, Fritz BA, Maybrier HR, Muench MR, Escallier KE, Chen Y, Ben Abdallah A, Veselis RA, Hudetz JA, Pagel PS, Noh G, Pryor K, Kaiser H, Arya VK, Pong R, Jacobsohn E, Grocott HP, Choi S, Downey RJ, Inouye SK, Mashour GA BMJ open 2014
Effectiveness and safety of the awakening and breathing coordination, delirium monitoring/management, and early exercise/mobility bundle. Balas MC, Vasilevskis EE, Olsen KM, Schmid KK, Shostrom V, Cohen MZ, Peitz G, Gannon DE, Sisson J, Sullivan J, Stothert JC, Lazure J, Nuss SL, Jawa RS, Freihaut F, Ely EW, Burke WJ Critical care medicine 2014

Adult, Aged, Clinical Protocols, Cohort Studies, Delirium, therapy, Exercise, Female, Humans, Hypnotics and Sedatives, therapeutic use, Immobilization, adverse effects, Intensive Care, methods, Male, Middle Aged, Prospective Studies, Regression Analysis, Respiration, Artificial, adverse effects, Treatment Outcome, Ventilator Weaning, methods

Comparison of symptoms of delirium across various motoric subtypes. Grover S, Sharma A, Aggarwal M, Mattoo SK, Chakrabarti S, Malhotra S, Avasthi A, Kulhara P, Basu D Psychiatry and clinical neurosciences 2014
The efficacy of peri-operative interventions to decrease postoperative delirium in non-cardiac surgery: a systematic review and meta-analysis. Moyce Z, Rodseth RN, Biccard BM Anaesthesia 2014

Delirium, prevention & control, Humans, Perioperative Care, methods, Postoperative Complications, prevention & control, Referral and Consultation

Interleukin 6 and apolipoprotein E as predictors of acute brain dysfunction and survival in critical care patients. Alexander SA, Ren D, Gunn SR, Kochanek PM, Tate J, Ikonomovic M, Conley YP American journal of critical care : an official publication, American Association of Critical-Care Nurses 2014
Decreasing inappropriate unable-to-assess ratings for the confusion assessment method for the intensive care unit. Swan JT American journal of critical care : an official publication, American Association of Critical-Care Nurses 2014
Anticholinergic activity in cerebrospinal fluid and serum in individuals with hip fracture with and without delirium. Watne LO, Hall RJ, Molden E, Raeder J, Frihagen F, MacLullich AM, Juliebø V, Nyman A, Meagher D, Wyller TB Journal of the American Geriatrics Society 2014

APACHE, Activities of Daily Living, Aged, Aged, 80 and over, Cholinergic Antagonists, blood, Comorbidity, Delirium, diagnosis, Female, Hip Fractures, complications, Humans, Male, Middle Aged, Norway, Prospective Studies, Questionnaires, Scotland, Severity of Illness Index

Antipsychotics for delirium in the general hospital setting in consecutive 2453 inpatients: a prospective observational study. Hatta K, Kishi Y, Wada K, Odawara T, Takeuchi T, Shiganami T, Tsuchida K, Oshima Y, Uchimura N, Akaho R, Watanabe A, Taira T, Nishimura K, Hashimoto N, Usui C, Nakamura H International journal of geriatric psychiatry 2014
The CAM-S: development and validation of a new scoring system for delirium severity in 2 cohorts. Inouye SK, Kosar CM, Tommet D, Schmitt EM, Puelle MR, Saczynski JS, Marcantonio ER, Jones RN Annals of internal medicine 2014

Activities of Daily Living, Aged, Aged, 80 and over, Cognition Disorders, diagnosis, Delirium, diagnosis, Female, Hospital Costs, Humans, Length of Stay, Male, Nursing Homes, Psychological Tests, Psychometrics, Severity of Illness Index

A tale of two methods: chart and interview methods for identifying delirium. Saczynski JS, Kosar CM, Xu G, Puelle MR, Schmitt E, Jones RN, Marcantonio ER, Wong B, Isaza I, Inouye SK Journal of the American Geriatrics Society 2014

Aged, Aged, 80 and over, Cohort Studies, Delirium, diagnosis, Female, Humans, Interview, Psychological, methods, Male, Medical Records, Prospective Studies, Psychological Tests, Reproducibility of Results, Severity of Illness Index

Effect of leaflet-based intervention on family members of terminally ill patients with cancer having delirium: historical control study. Otani H, Morita T, Uno S, Yamamoto R, Hirose H, Matsubara T, Takigawa C, Sasaki K The American journal of hospice & palliative care 2014
Preparation to care for confused older patients in general hospitals: a study of UK health professionals. Griffiths A, Knight A, Harwood R, Gladman JR Age and ageing 2014
Prediction of delirium in critically ill patients with elevated C-reactive protein. Zhang Z, Pan L, Deng H, Ni H, Xu X Journal of critical care 2014
Barriers and facilitators to implementing delirium rounds in a clinical trial across three diverse hospital settings. Yevchak AM, Fick DM, McDowell J, Monroe T, May K, Grove L, Kolanowski AM, Waller JL, Inouye SK Clinical nursing research 2014
Feasibility and acceptability of a delirium prevention program for cognitively impaired long term care residents: a participatory approach. Voyer P, McCusker J, Cole MG, Monette J, Champoux N, Vu M, Ciampi A, Sanche S, Richard S, de Raad M Journal of the American Medical Directors Association 2014
Safety incidents involving confused and forgetful older patients in a specialised care setting - analysis of the safety incidents reported to the HaiPro reporting system. Kinnunen-Luovi K, Saarnio R, Isola A Journal of clinical nursing 2014
Prognosis of delirium in hospitalized elderly: worse than we thought. Dasgupta M, Brymer C International journal of geriatric psychiatry 2014
Delirium in the ICU and subsequent long-term disability among survivors of mechanical ventilation. Brummel NE, Jackson JC, Pandharipande PP, Thompson JL, Shintani AK, Dittus RS, Gill TM, Bernard GR, Ely EW, Girard TD Critical care medicine 2014

Activities of Daily Living, Aged, Delirium, complications, Female, Humans, Intensive Care Units, Male, Middle Aged, Prospective Studies, Questionnaires, Respiration, Artificial, Survivors, Time Factors

Validation and psychometric properties of the Delirium Motor Subtype Scale in elderly hip fracture patients (Dutch version). Slor CJ, Adamis D, Jansen RW, Meagher DJ, Witlox J, Houdijk AP, de Jonghe JF Archives of gerontology and geriatrics 2014

Aged, Aged, 80 and over, Delirium, classification, Female, Fracture Fixation, Hip Fractures, complications, Humans, Male, Motor Activity, Netherlands, Psychiatric Status Rating Scales, ROC Curve, Reproducibility of Results, Severity of Illness Index

Delirium is a predictor of in-hospital mortality in elderly patients with community acquired pneumonia. Pieralli F, Vannucchi V, Mancini A, Grazzini M, Paolacci G, Morettini A, Nozzoli C Internal and emergency medicine 2014