What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Exercise for acutely hospitalised older medical patients
- Authors
- Hartley, P. Keating, J. L. Jeffs, K. J. Raymond, M. J. Smith, T. O
- Year
- 2022
- Journal
- Cochrane Database Syst Rev
- Abstract
BACKGROUND: Approximately 30% of hospitalised older adults experience hospital-associated functional decline. Exercise interventions that promote in-hospital activity may prevent deconditioning and thereby maintain physical function during hospitalisation. This is an update of a Cochrane Review first published in 2007. OBJECTIVES: To evaluate the benefits and harms of exercise interventions for acutely hospitalised older medical inpatients on functional ability, quality of life (QoL), participant global assessment of success and adverse events compared to usual care or a sham-control intervention. SEARCH METHODS: We used standard, extensive Cochrane search methods. The latest search date was May 2021. SELECTION CRITERIA: We included randomised or quasi-randomised controlled trials evaluating an in-hospital exercise intervention in people aged 65 years or older admitted to hospital with a general medical condition. We excluded people admitted for elective reasons or surgery. DATA COLLECTION AND ANALYSIS: We used standard Cochrane methods. Our major outcomes were 1. independence with activities of daily living; 2. functional mobility; 3. new incidence of delirium during hospitalisation; 4. QoL; 5. number of falls during hospitalisation; 6. medical deterioration during hospitalisation and 7. participant global assessment of success. Our minor outcomes were 8. death during hospitalisation; 9. musculoskeletal injuries during hospitalisation; 10. hospital length of stay; 11. new institutionalisation at hospital discharge; 12. hospital readmission and 13. walking performance. We used GRADE to assess certainty of evidence for each major outcome. We categorised exercise interventions as: rehabilitation-related activities (interventions designed to increase physical activity or functional recovery, but did not follow a specified exercise protocol); structured exercise (interventions that included an exercise intervention protocol but did not include progressive resistance training); and progressive resistance exercise (interventions that included an element of progressive resistance training). MAIN RESULTS: We included 24 studies (nine rehabilitation-related activity interventions, six structured exercise interventions and nine progressive resistance exercise interventions) with 7511 participants. All studies compared exercise interventions to usual care; two studies, in addition to usual care, used sham interventions. Mean ages ranged from 73 to 88 years, and 58% of participants were women. Several studies were at high risk of bias. The most common domain assessed at high risk of bias was measurement of the outcome, and five studies (21%) were at high risk of bias arising from the randomisation process. Exercise may have no clinically important effect on independence in activities of daily living at discharge from hospital compared to controls (16 studies, 5174 participants; low-certainty evidence). Five studies used the Barthel Index (scale: 0 to 100, higher scores representing greater independence). Mean scores at discharge in the control groups ranged from 42 to 96 points, and independence in activities of daily living was 1.8 points better (0.43 worse to 4.12 better) with exercise compared to controls. The minimally clinical important difference (MCID) is estimated to be 11 points. We are uncertain regarding the effect of exercise on functional mobility at discharge from the hospital compared to controls (8 studies, 2369 participants; very low-certainty evidence). Three studies used the Short Physical Performance Battery (SPPB) (scale: 0 to 12, higher scores representing better function) to measure functional mobility. Mean scores at discharge in the control groups ranged from 3.7 to 4.9 points on the SPPB, and the estimated effect of the exercise interventions was 0.78 points better (0.02 worse to 1.57 better). A change of 1 point on the SPPB represents an MCID. We are uncertain regarding the effect of exercise on the incidence of delirium during hospitalisation compared to controls (7 trials, 2088 participants; very low-certainty evidence). The incidence of delirium during hospitalisation was 88/1091 (81 per 1000) in the control group compared with 70/997 (73 per 1000; range 47 to 114) in the exercise group (RR 0.90, 95% CI 0.58 to 1.41). Exercise interventions may result in a small clinically unimportant improvement in QoL at discharge from the hospital compared to controls (4 studies, 875 participants; low-certainty evidence). Mean QoL on the EuroQol 5 Dimensions (EQ-5D) visual analogue scale (VAS) (scale: 0 to 100, higher scores representing better QoL) ranged between 48.9 and 64.7 in the control group at discharge from the hospital, and QoL was 6.04 points better (0.9 better to 11.18 better) with exercise. A change of 10 points on the EQ-5D VAS represents an MCID. No studies measured participant global assessment of success. Exercise interventions did not affect the risk of falls during hospitalisation (moderate-certainty evidence). The incidence of falls was 31/899 (34 per 1000) in the control group compared with 31/888 (34 per 1000; range 20 to 57) in the exercise group (RR 0.99, 95% CI 0.59 to 1.65). We are uncertain regarding the effect of exercise on the incidence of medical deterioration during hospitalisation (very low-certainty evidence). The incidence of medical deterioration in the control group was 101/1417 (71 per 1000) compared with 96/1313 (73 per 1000; range 44 to 120) in the exercise group (RR 1.02, 95% CI 0.62 to 1.68). Subgroup analyses by different intervention categories and by the use of a sham intervention were not meaningfully different from the main analyses. AUTHORS’ CONCLUSIONS: Exercise may make little difference to independence in activities of daily living or QoL, but probably does not result in more falls in older medical inpatients. We are uncertain about the effect of exercise on functional mobility, incidence of delirium and medical deterioration. Certainty of evidence was limited by risk of bias and inconsistency. Future primary research on the effect of exercise on acute hospitalisation could focus on more consistent and uniform reporting of participant’s characteristics including their baseline level of functional ability, as well as exercise dose, intensity and adherence that may provide an insight into the reasons for the observed inconsistencies in findings.
- PMID
- Keywords
Aged
Aged, 80 and over
Female
Humans
Male
Activities of Daily Living
*Delirium/epidemiology
Exercise
*Quality of Life
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Canadian Cardiovascular Society consensus conference recommendations on heart failure 2006: diagnosis and management. | Arnold JM, Liu P, Demers C, Dorian P, Giannetti N, Haddad H, Heckman GA, Howlett JG, Ignaszewski A, Johnstone DE, Jong P, McKelvie RS, Moe GW, Parker JD, Rao V, Ross HJ, Sequeira EJ, Svendsen AM, Teo K, Tsuyuki RT, White M, | The Canadian journal of cardiology | 2006 |
Canada, Cardiac Surgical Procedures, methods, Cardiology, Cardiovascular Agents, therapeutic use, Defibrillators, Implantable, Exercise Therapy, methods, Heart Failure, diagnosis, Humans, Societies, Medical |
| Does home treatment affect delirium? A randomised controlled trial of rehabilitation of elderly and care at home or usual treatment (The REACH-OUT trial). | Caplan GA, Coconis J, Board N, Sayers A, Woods J | Age and ageing | 2006 |
Aged, Delirium, etiology, Female, Follow-Up Studies, Health Status, Home Care Services, Hospitalization, Humans, Male, Patient Satisfaction, Psychiatric Status Rating Scales, Questionnaires, Retrospective Studies, Treatment Outcome |
| Early evaluation of the risk of functional decline following hospitalization of older patients: development of a predictive tool. | Cornette P, Swine C, Malhomme B, Gillet JB, Meert P, D'Hoore W | European journal of public health | 2006 |
Activities of Daily Living, Aged, Aged, 80 and over, Cohort Studies, Female, Frail Elderly, Humans, Interviews as Topic, Male, Patient Discharge, Prospective Studies, Risk Assessment |
| Delirium concisely: condition is associated with increased morbidity, mortality, and length of hospitalization. | van Zyl LT, Seitz DP | Geriatrics | 2006 |
Aged, Antipsychotic Agents, therapeutic use, Combined Modality Therapy, Delirium, complications, Dementia, etiology, Female, Geriatric Assessment, statistics & numerical data, Hospital Mortality, Humans, Institutionalization, statistics & numerical data, Length of Stay, statistics & numerical data, Male, Outcome Assessment (Health Care), Risk |
| Influence of prior cognitive impairment on the severity of delirium symptoms among older patients. | Voyer P, McCusker J, Cole MG, Khomenko L | The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses | 2006 |
Aged, Aged, 80 and over, Cognition Disorders, epidemiology, Delirium, diagnosis, Dementia, epidemiology, Female, Humans, Male, Movement Disorders, diagnosis, Neuropsychological Tests, Prevalence, Severity of Illness Index, Socioeconomic Factors |
| Multicomponent geriatric intervention for elderly inpatients with delirium: a randomized, controlled trial. | Pitkälä KH, Laurila JV, Strandberg TE, Tilvis RS | The journals of gerontology. Series A, Biological sciences and medical sciences | 2006 |
Aged, Aged, 80 and over, Antipsychotic Agents, therapeutic use, Cholinesterase Inhibitors, therapeutic use, Delirium, therapy, Female, Humans, Inpatients, Male, Physical Therapy Modalities, Referral and Consultation, Treatment Outcome |
| Delirium within three days of stroke in a cohort of elderly patients. | Sheng AZ, Shen Q, Cordato D, Zhang YY, Yin Chan DK | Journal of the American Geriatrics Society | 2006 |
Age Factors, Aged, Aged, 80 and over, Delirium, epidemiology, Female, Follow-Up Studies, Humans, Incidence, Length of Stay, Male, New South Wales, epidemiology, Odds Ratio, Prognosis, Prospective Studies, Risk Factors, Stroke, complications, Survival Rate, Time Factors |
| Delirium in older patients admitted to general internal medicine. | Edlund A, Lundström M, Karlsson S, Brännström B, Bucht G, Gustafson Y | Journal of geriatric psychiatry and neurology | 2006 |
Aged, Aged, 80 and over, Delirium, diagnosis, Female, Hospitals, General, Humans, Internal Medicine, Length of Stay, Male, Patient Admission, Psychiatric Status Rating Scales, Survival Rate, Sweden, epidemiology, Time Factors |
| Assessment and discharge planning for hospitalized older adults with delirium. | Cole CS, Williams EB, Williams RD | Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses | 2006 |
Aged, Aged, 80 and over, Delirium, diagnosis, Female, Geriatric Assessment, methods, Humans, Needs Assessment, organization & administration, Nurse’s Role, Nursing Assessment, methods, Patient Care Planning, Patient Discharge, Risk Assessment, methods, Safety Management |
| Risperidone versus olanzapine for the treatment of delirium. | Kim SW, Yoo JA, Lee SY, Kim SY, Bae KY, Yang SJ, Kim JM, Shin IS, Yoon JS | Human psychopharmacology | 2010 |
Adult, Aged, 80 and over, Antipsychotic Agents, adverse effects, Benzodiazepines, adverse effects, Data Interpretation, Statistical, Delirium, drug therapy, Diagnostic and Statistical Manual of Mental Disorders, Female, Humans, Male, Risperidone, adverse effects, Treatment Outcome |
| Incidence and predictors of delirium after cardiac surgery: Results from The IPDACS Study. | Kazmierski J, Kowman M, Banach M, Fendler W, Okonski P, Banys A, Jaszewski R, Rysz J, Mikhailidis DP, Sobow T, Kloszewska I, | Journal of psychosomatic research | 2010 |
Age Factors, Aged, Anemia, epidemiology, Atrial Fibrillation, epidemiology, Cardiopulmonary Bypass, psychology, Comorbidity, Cross-Sectional Studies, Delirium, epidemiology, Depressive Disorder, Major, diagnosis, Female, Health Status Indicators, Heart Diseases, psychology, Humans, Incidence, Male, Mental Disorders, epidemiology, Mental Status Schedule, Postoperative Complications, epidemiology, Risk Factors |
| Delirium in elderly patients and the risk of postdischarge mortality, institutionalization, and dementia: a meta-analysis. | Witlox J, Eurelings LS, de Jonghe JF, Kalisvaart KJ, Eikelenboom P, van Gool WA | JAMA : the journal of the American Medical Association | 2010 |
Aged, Aged, 80 and over, Case-Control Studies, Confounding Factors (Epidemiology), Delirium, complications, Dementia, complications, Humans, Institutionalization, statistics & numerical data, Odds Ratio |
| Serum S100B in elderly patients with and without delirium. | van Munster BC, Korevaar JC, Korse CM, Bonfrer JM, Zwinderman AH, de Rooij SE | International journal of geriatric psychiatry | 2010 |
Age Factors, Aged, Aged, 80 and over, Biological Markers, blood, Cognition Disorders, blood, Delirium, blood, Female, Humans, Male, Psychiatric Status Rating Scales, S100 Proteins, blood |
| A national survey of the management of delirium in UK intensive care units. | Mac Sweeney R, Barber V, Page V, Ely EW, Perkins GD, Young JD, McAuley DF, | QJM : monthly journal of the Association of Physicians | 2010 |
Antipsychotic Agents, therapeutic use, Delirium, diagnosis, Delivery of Health Care, standards, Great Britain, Haloperidol, therapeutic use, Humans, Intensive Care Units, standards, Questionnaires |
| Delirium following acute myocardial infarction: incidence, clinical profiles, and predictors. | Uguz F, Kayrak M, Cíçek E, Kayhan F, Ari H, Altunbas G | Perspectives in psychiatric care | 2010 |
Case-Control Studies, Chi-Square Distribution, Delirium, diagnosis, Female, Heart Arrest, complications, Hospitals, University, Humans, Hyperkalemia, blood, Incidence, Length of Stay, statistics & numerical data, Male, Middle Aged, Myocardial Infarction, complications, Predictive Value of Tests, Prevalence, Risk Factors, Severity of Illness Index, Socioeconomic Factors, Statistics, Nonparametric, Turkey, epidemiology |
| Neuroleptic dose in the management of delirium in patients with advanced cancer. | Hui D, Bush SH, Gallo LE, Palmer JL, Yennurajalingam S, Bruera E | Journal of pain and symptom management | 2010 |
Adult, Affective Symptoms, psychology, Aged, Aged, 80 and over, Algorithms, Antipsychotic Agents, administration & dosage, Delirium, drug therapy, Dose-Response Relationship, Drug, Female, Haloperidol, administration & dosage, Humans, Male, Mental Recall, Middle Aged, Neoplasms, complications, Neuropsychological Tests, Psychiatric Status Rating Scales |
| Impaired mobility, ASA status and administration of tramadol are risk factors for postoperative delirium in patients aged 75 years or more after major abdominal surgery. | Brouquet A, Cudennec T, Benoist S, Moulias S, Beauchet A, Penna C, Teillet L, Nordlinger B | Annals of surgery | 2010 |
Abdomen, surgery, Aged, Aged, 80 and over, Analgesics, Opioid, adverse effects, Cognition, Delirium, diagnosis, Geriatric Assessment, Health Status, Humans, Mental Status Schedule, Mobility Limitation, Postoperative Complications, etiology, Risk Factors, Tramadol, adverse effects |
| Does this patient have delirium?: value of bedside instruments. | Wong CL, Holroyd-Leduc J, Simel DL, Straus SE | JAMA | 2010 |
Aged, Delirium, diagnosis, Diagnostic and Statistical Manual of Mental Disorders, Humans, Mental Status Schedule, Point-of-Care Systems, Prospective Studies, Sensitivity and Specificity |
| Randomized trial of a delirium abatement program for postacute skilled nursing facilities. | Marcantonio ER, Bergmann MA, Kiely DK, Orav EJ, Jones RN | Journal of the American Geriatrics Society | 2010 |
Aged, 80 and over, Chi-Square Distribution, Delirium, diagnosis, Female, Humans, Logistic Models, Male, Mental Status Schedule, Nursing Assessment, Nursing Diagnosis, Skilled Nursing Facilities, Treatment Outcome |
| Cortisol, interleukins and S100B in delirium in the elderly. | van Munster BC, Bisschop PH, Zwinderman AH, Korevaar JC, Endert E, Wiersinga WJ, van Oosten HE, Goslings JC, de Rooij SE | Brain and cognition | 2010 |
Aged, Aged, 80 and over, Biological Markers, blood, Delirium, blood, Female, Hip Fractures, blood, Humans, Hydrocortisone, blood, Immunoassay, Interleukin-6, blood, Interleukin-8, blood, Male, Nerve Growth Factors, blood, S100 Calcium Binding Protein beta Subunit, S100 Proteins, blood |
| Prevalence of delirium on admission to postacute care is associated with a higher number of nursing home deficiencies. | Jones RN, Kiely DK, Marcantonio ER | Journal of the American Medical Directors Association | 2010 |
Acute Disease, Aged, Boston, epidemiology, Delirium, diagnosis, Humans, Mass Screening, Patient Admission, Quality of Health Care, Randomized Controlled Trials as Topic, Skilled Nursing Facilities, standards, United States, epidemiology |
| Validating a new clinical subtyping scheme for delirium with electronic motion analysis. | Godfrey A, Leonard M, Donnelly S, Conroy M, Olaighin G, Meagher D | Psychiatry research | 2010 |
Accelerometry, Adult, Aged, Aged, 80 and over, Checklist, Delirium, classification, Diagnosis, Computer-Assisted, instrumentation, Female, Humans, Male, Middle Aged, Movement, Neuropsychological Tests, Psychiatric Status Rating Scales |
| Potentially inappropriate medication use in older adults with mild cognitive impairment. | Weston AL, Weinstein AM, Barton C, Yaffe K | The journals of gerontology. Series A, Biological sciences and medical sciences | 2010 |
Aged, California, epidemiology, Cognition Disorders, drug therapy, Cross-Sectional Studies, Female, Follow-Up Studies, Humans, Male, Medication Errors, statistics & numerical data, Prevalence, Prognosis, Retrospective Studies, Risk Factors |
| Delirium in intensive care unit patients. | van Eijk MM, Slooter AJ | Seminars in cardiothoracic and vascular anesthesia | 2010 |
Cardiac Surgical Procedures, adverse effects, Critical Illness, Delirium, diagnosis, Humans, Intensive Care, methods, Intensive Care Units, statistics & numerical data, Length of Stay, Postoperative Complications, diagnosis |
| Factors associated with persistent delirium after intensive care unit admission in an older medical patient population. | Pisani MA, Murphy TE, Araujo KL, Van Ness PH | Journal of critical care | 2010 |
Age Factors, Aged, Analgesics, Opioid, adverse effects, Analysis of Variance, Delirium, chemically induced, Dementia, epidemiology, Haloperidol, adverse effects, Humans, Intensive Care, Intensive Care Units, Middle Aged, Patient Admission, Prospective Studies, Psychotropic Drugs, adverse effects, Risk Factors, Severity of Illness Index |
| Incidence, prevalence, and under-recognition of delirium in urology patients. | Vollmer CM, Bond J, Eden BM, Resch DS, Fulk L, Robinson S, Hughes LE | Urologic nursing | 2010 |
Age Distribution, Aged, Aged, 80 and over, Comorbidity, Delirium, diagnosis, Documentation, Female, Humans, Incidence, Inpatients, statistics & numerical data, Length of Stay, statistics & numerical data, Male, Middle Aged, Midwestern United States, epidemiology, Nursing Assessment, methods, Nursing Records, Prevalence, Prospective Studies, Risk Factors, Sex Distribution, Urologic Diseases, complications |
| Delirium in older cardiac surgery patients: directions for practice. | Clarke SP, McRae ME, Del Signore S, Schubert M, Styra R | Journal of gerontological nursing | 2010 |
Aged, Delirium, complications, Humans, Monitoring, Physiologic, Thoracic Surgery |
| Delirium superimposed on dementia. Assessment and intervention. | Flanagan NM, Fick DM | Journal of gerontological nursing | 2010 |
Aged, Delirium, complications, Dementia, complications, Humans, Nursing Assessment |
| A systematic review of the reliability of screening for cognitive impairment in older adults by use of standardised assessment tools administered via the telephone. | Martin-Khan M, Wootton R, Gray L | Journal of telemedicine and telecare | 2010 |
Aged, Aged, 80 and over, Cognition Disorders, diagnosis, Delirium, diagnosis, Evaluation Studies as Topic, Geriatric Assessment, methods, Humans, Neuropsychological Tests, Psychiatric Status Rating Scales, Reproducibility of Results, Severity of Illness Index, Telephone |
| Brief cognitive screening instruments: an update. | Ismail Z, Rajji TK, Shulman KI | International journal of geriatric psychiatry | 2010 |
Aged, Aged, 80 and over, Attitude of Health Personnel, Cognition Disorders, diagnosis, Dementia, diagnosis, Female, Geriatric Assessment, methods, Great Britain, Humans, Male, Mass Screening, instrumentation, Primary Health Care, Psychometrics, methods |
| Screening and case finding tools for the detection of dementia. Part I: evidence-based meta-analysis of multidomain tests. | Mitchell AJ, Malladi S | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry | 2010 |
Aged, Case Management, organization & administration, Cognition, Dementia, diagnosis, Evaluation Studies as Topic, Evidence-Based Medicine, instrumentation, Executive Function, Geriatric Assessment, methods, Humans, Intelligence Tests, standards, Interviews as Topic, standards, Mass Screening, instrumentation, Memory Disorders, diagnosis, Mental Recall, Mental Status Schedule, Meta-Analysis as Topic, Primary Health Care, methods, Reproducibility of Results, Severity of Illness Index |
| Delirium as a predictor of sepsis in post-coronary artery bypass grafting patients: a retrospective cohort study. | Martin BJ, Buth KJ, Arora RC, Baskett RJ | Critical care (London, England) | 2010 |
Aged, Cohort Studies, Coronary Artery Bypass, adverse effects, Delirium, diagnosis, Female, Humans, Male, Postoperative Complications, diagnosis, Predictive Value of Tests, Prospective Studies, Retrospective Studies, Sepsis, diagnosis, Treatment Outcome |
| Inflammation and cortisol response in coronary artery disease. | Nijm J, Jonasson L | Annals of medicine | 2009 |
Autoimmunity, Biological Markers, blood, Coronary Artery Disease, blood, Glucocorticoids, blood, Humans, Hydrocortisone, blood, Hypothalamo-Hypophyseal System, physiopathology, Inflammation, immunology, Myocardial Infarction, blood, Neuroimmunomodulation, Pituitary-Adrenal System, physiopathology, Stress, Physiological |
| Validation of a German version of the Confusion Assessment Method for delirium detection in a sample of acute geriatric patients with a high prevalence of dementia. | Hestermann U, Backenstrass M, Gekle I, Hack M, Mundt C, Oster P, Thomas C | Psychopathology | 2009 |
Acute Disease, Aged, Aged, 80 and over, Algorithms, Comorbidity, Confusion, diagnosis, Delirium, diagnosis, Dementia, diagnosis, Diagnosis, Differential, Diagnostic and Statistical Manual of Mental Disorders, Female, Frail Elderly, psychology, Germany, Hospitalization, Humans, Male, Mental Status Schedule, statistics & numerical data, Neuropsychological Tests, statistics & numerical data, Personality Assessment, statistics & numerical data, Psychometrics, statistics & numerical data, Reproducibility of Results, Risk Factors |
| Benzodiazepine and opioid use and the duration of intensive care unit delirium in an older population. | Pisani MA, Murphy TE, Araujo KL, Slattum P, Van Ness PH, Inouye SK | Critical care medicine | 2009 |
Aged, Analgesics, Opioid, adverse effects, Benzodiazepines, adverse effects, Delirium, epidemiology, Female, Humans, Intensive Care Units, Male, Prospective Studies, Time Factors |
| The ironic business case for chronic care in the acute care setting. | Siu AL, Spragens LH, Inouye SK, Morrison RS, Leff B | Health affairs (Project Hope) | 2009 |
Chronic Disease, therapy, Economics, Hospital, organization & administration, Emergency Service, Hospital, Humans, Quality of Health Care, United States |
| Microemboli are not associated with delirium after coronary artery bypass graft surgery. | Rudolph JL, Babikian VL, Treanor P, Pochay VE, Wigginton JB, Crittenden MD, Marcantonio ER | Perfusion | 2009 |
Aged, Aged, 80 and over, Cerebrum, pathology, Coronary Artery Bypass, adverse effects, Delirium, etiology, Embolism, etiology, Female, Humans, Male, Middle Aged |
| Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial. | Riker RR, Shehabi Y, Bokesch PM, Ceraso D, Wisemandle W, Koura F, Whitten P, Margolis BD, Byrne DW, Ely EW, Rocha MG, | JAMA : the journal of the American Medical Association | 2009 |
APACHE, Adrenergic alpha-Agonists, administration & dosage, Aged, Conscious Sedation, methods, Critical Illness, Delirium, epidemiology, Dexmedetomidine, administration & dosage, Double-Blind Method, Female, GABA Modulators, administration & dosage, Humans, Hypnotics and Sedatives, administration & dosage, Intensive Care Units, Kaplan-Meier Estimate, Length of Stay, Male, Midazolam, administration & dosage, Middle Aged, Prospective Studies, Respiration, Artificial |
| Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial. | Schweickert WD, Pohlman MC, Pohlman AS, Nigos C, Pawlik AJ, Esbrook CL, Spears L, Miller M, Franczyk M, Deprizio D, Schmidt GA, Bowman A, Barr R, McCallister KE, Hall JB, Kress JP | Lancet | 2009 |
Activities of Daily Living, Adult, Aged, Bed Rest, adverse effects, Chicago, Conscious Sedation, adverse effects, Critical Care, methods, Critical Illness, rehabilitation, Delirium, etiology, Early Ambulation, methods, Exercise Therapy, methods, Female, Humans, Iowa, Kaplan-Meier Estimate, Logistic Models, Male, Middle Aged, Mobility Limitation, Occupational Therapy, methods, Proportional Hazards Models, Respiration, Artificial, adverse effects, Single-Blind Method, Statistics, Nonparametric, Time Factors, Treatment Outcome |
| The genetics of deliria. | Adamis D, Van Munster BC, Macdonald AJ | International review of psychiatry (Abingdon, England) | 2009 |
Apolipoproteins E, genetics, Brain, metabolism, Catechol O-Methyltransferase, genetics, Delirium, epidemiology, Female, Genotype, Glutamic Acid, metabolism, Humans, Male, Polymorphism, Genetic, genetics, Substance-Related Disorders, metabolism |
| The neuropsychopharmacology of fronto-executive function: monoaminergic modulation. | Robbins TW, Arnsten AF | Annual review of neuroscience | 2009 |
Animals, Catecholamines, metabolism, Cognition, physiology, Delirium, Dementia, Amnestic, Cognitive Disorders, metabolism, Humans, Mental Processes, physiology, Neuropharmacology, methods, Prefrontal Cortex, anatomy & histology, Psychomotor Performance, physiology, Serotonin, metabolism, Synaptic Transmission, physiology |
| Derivation and validation of a preoperative prediction rule for delirium after cardiac surgery. | Rudolph JL, Jones RN, Levkoff SE, Rockett C, Inouye SK, Sellke FW, Khuri SF, Lipsitz LA, Ramlawi B, Levitsky S, Marcantonio ER | Circulation | 2009 |
Aged, Aged, 80 and over, Cardiac Surgical Procedures, adverse effects, Cohort Studies, Delirium, diagnosis, Female, Humans, Male, Postoperative Complications, diagnosis, Predictive Value of Tests, Preoperative Care, methods, Prospective Studies, Risk Factors |
| Delirium in older emergency department patients: recognition, risk factors, and psychomotor subtypes. | Han JH, Zimmerman EE, Cutler N, Schnelle J, Morandi A, Dittus RS, Storrow AB, Ely EW | Academic emergency medicine : official journal of the Society for Academic Emergency Medicine | 2009 |
Aged, Aged, 80 and over, Cross-Sectional Studies, Delirium, diagnosis, Emergency Service, Hospital, Female, Geriatric Assessment, Humans, Logistic Models, Male, Medical Errors, prevention & control, Mental Status Schedule, Prospective Studies, Psychomotor Agitation, ROC Curve, Risk Assessment, Risk Factors, Sensitivity and Specificity, Statistics, Nonparametric |
| Predictors of falls and hospitalization outcomes in elderly patients admitted to an acute geriatric unit. | Corsinovi L, Bo M, Ricauda Aimonino N, Marinello R, Gariglio F, Marchetto C, Gastaldi L, Fissore L, Zanocchi M, Molaschi M | Archives of gerontology and geriatrics | 2009 |
Accidental Falls, statistics & numerical data, Acute Disease, Aged, Catchment Area (Health), Female, Health Services for the Aged, Hospitalization, statistics & numerical data, Humans, Italy, epidemiology, Male, Patient Admission, statistics & numerical data, Prospective Studies |
| Persistent delirium in older hospital patients: a systematic review of frequency and prognosis. | Cole MG, Ciampi A, Belzile E, Zhong L | Age and ageing | 2009 |
Aged, Aged, 80 and over, Delirium, diagnosis, Geriatric Assessment, Humans, Inpatients, Middle Aged, Prevalence, Prognosis |
| Ketamine attenuates delirium after cardiac surgery with cardiopulmonary bypass. | Hudetz JA, Patterson KM, Iqbal Z, Gandhi SD, Byrne AJ, Hudetz AG, Warltier DC, Pagel PS | Journal of cardiothoracic and vascular anesthesia | 2009 |
Aged, Aged, 80 and over, Cardiac Surgical Procedures, adverse effects, Cardiopulmonary Bypass, adverse effects, Delirium, etiology, Humans, Inflammation Mediators, therapeutic use, Ketamine, therapeutic use, Male, Middle Aged, Postoperative Complications, etiology, Prospective Studies, Time Factors |
| Delirium and long-term cognitive impairment. | MacLullich AM, Beaglehole A, Hall RJ, Meagher DJ | International review of psychiatry (Abingdon, England) | 2009 |
Cognition Disorders, diagnosis, Delirium, epidemiology, Humans, Neuropsychological Tests, Time Factors |
| Cross validation of the Montreal Cognitive Assessment in community dwelling older adults residing in the Southeastern US. | Luis CA, Keegan AP, Mullan M | International journal of geriatric psychiatry | 2009 |
Aged, Aged, 80 and over, Alzheimer Disease, diagnosis, Cognition Disorders, diagnosis, Cohort Studies, Female, Humans, Male, Mass Screening, methods, Neuropsychological Tests, standards, Prospective Studies, ROC Curve, Reproducibility of Results, Sensitivity and Specificity, United States |
| An intervention integrated into daily clinical practice reduces the incidence of delirium during hospitalization in elderly patients. | Vidán MT, Sánchez E, Alonso M, Montero B, Ortiz J, Serra JA | Journal of the American Geriatrics Society | 2009 |
APACHE, Activities of Daily Living, classification, Aged, Aged, 80 and over, Combined Modality Therapy, Cooperative Behavior, Cross-Sectional Studies, Delirium, epidemiology, Female, Hospitalization, Humans, Incidence, Inservice Training, Interdisciplinary Communication, Male, Mental Status Schedule, Patient Care Team, Risk Factors, Spain |
| Postoperative delirium in the elderly surgical patient. | Sieber FE | Anesthesiology clinics | 2009 |
Aged, Anesthesia, Arthroplasty, Replacement, Hip, Delirium, diagnosis, Female, Femoral Neck Fractures, surgery, Humans, Postoperative Complications, psychology, Pulmonary Disease, Chronic Obstructive, complications |
| Fascia iliaca block prophylaxis for hip fracture patients at risk for delirium: a randomized placebo-controlled study. | Mouzopoulos G, Vasiliadis G, Lasanianos N, Nikolaras G, Morakis E, Kaminaris M | Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology | 2009 |
Aged, Anesthetics, Local, administration & dosage, Bupivacaine, administration & dosage, Delirium, diagnosis, Female, Fracture Fixation, Internal, adverse effects, Hip Fractures, complications, Humans, Male, Nerve Block, methods, Pain, etiology, Perioperative Care, methods, Prospective Studies, Risk Assessment, Severity of Illness Index, Treatment Outcome |
| Days of delirium are associated with 1-year mortality in an older intensive care unit population. | Pisani MA, Kong SY, Kasl SV, Murphy TE, Araujo KL, Van Ness PH | American journal of respiratory and critical care medicine | 2009 |
Aged, Cohort Studies, Connecticut, epidemiology, Delirium, epidemiology, Female, Follow-Up Studies, Geriatric Assessment, methods, Humans, Intensive Care Units, statistics & numerical data, Kaplan-Meier Estimate, Male, Prospective Studies, Risk Factors, Time Factors |
| Effects of an interdisciplinary nurse-led Delirium Prevention and Management Program (DPMP) on nursing workload: a pilot study. | Pretto M, Spirig R, Milisen K, Degeest S, Regazzoni P, Hasemann W | International journal of nursing studies | 2009 |
Aged, Aged, 80 and over, Delirium, complications, Female, Hip Fractures, complications, Humans, Male, Nursing, Pilot Projects, Workload |
| Predisposing factors associated with delirium among demented long-term care residents. | Voyer P, Richard S, Doucet L, Carmichael PH | Clinical nursing research | 2009 |
Aged, Cross-Sectional Studies, Delirium, complications, Dementia, complications, Disease Susceptibility, Humans, Likelihood Functions, Long-Term Care, Nursing Homes, Quebec |
| The overlap syndrome of depression and delirium in older hospitalized patients. | Givens JL, Jones RN, Inouye SK | Journal of the American Geriatrics Society | 2009 |
Academic Medical Centers, Activities of Daily Living, Aged, Aged, 80 and over, Connecticut, epidemiology, Delirium, complications, Depression, complications, Female, Geriatric Assessment, Hospitalization, statistics & numerical data, Humans, Incidence, Logistic Models, Male, Predictive Value of Tests, Prevalence, Proportional Hazards Models, Prospective Studies, Psychiatric Status Rating Scales |
| Risk factors for preoperative and postoperative delirium in elderly patients with hip fracture. | Juliebø V, Bjøro K, Krogseth M, Skovlund E, Ranhoff AH, Wyller TB | Journal of the American Geriatrics Society | 2009 |
Activities of Daily Living, Aged, Aged, 80 and over, Comorbidity, Delirium, epidemiology, Female, Hip Fractures, complications, Humans, Logistic Models, Male, Norway, epidemiology, Postoperative Complications, epidemiology, Prospective Studies, Risk Factors, Statistics, Nonparametric, Time Factors |
| Persistent delirium predicts greater mortality. | Kiely DK, Marcantonio ER, Inouye SK, Shaffer ML, Bergmann MA, Yang FM, Fearing MA, Jones RN | Journal of the American Geriatrics Society | 2009 |
Aged, Aged, 80 and over, Cohort Studies, Delirium, etiology, Female, Homes for the Aged, Hospitalization, Humans, Male, Nursing Homes |
| Plasma tryptophan and tyrosine levels are independent risk factors for delirium in critically ill patients. | Pandharipande PP, Morandi A, Adams JR, Girard TD, Thompson JL, Shintani AK, Ely EW | Intensive care medicine | 2009 |
Aged, Amino Acid Transport System L, blood, Analysis of Variance, Critical Illness, Delirium, blood, Disease Progression, Female, Humans, Logistic Models, Male, Markov Chains, Middle Aged, Phenylalanine, blood, Pilot Projects, Predictive Value of Tests, Regression Analysis, Risk Assessment, Risk Factors, Severity of Illness Index, Tennessee, Time Factors, Tryptophan, blood, Tyrosine, blood |
| Markers of cerebral damage during delirium in elderly patients with hip fracture. | van Munster BC, Korse CM, de Rooij SE, Bonfrer JM, Zwinderman AH, Korevaar JC | BMC neurology | 2009 |
Aged, Aged, 80 and over, Biological Markers, blood, Brain Injuries, blood, Delirium, blood, Female, Hip Fractures, blood, Humans, Male, Nerve Growth Factors, blood, Phosphopyruvate Hydratase, blood, Retrospective Studies, S100 Calcium Binding Protein beta Subunit, S100 Proteins, blood |
| Implementation of a delirium assessment tool in the ICU can influence haloperidol use. | van den Boogaard M, Pickkers P, van der Hoeven H, Roodbol G, van Achterberg T, Schoonhoven L | Critical care (London, England) | 2009 |
Adult, Aged, Antipsychotic Agents, administration & dosage, Delirium, diagnosis, Female, Guideline Adherence, Haloperidol, administration & dosage, Humans, Inservice Training, Intensive Care Units, Leadership, Male, Middle Aged, Reminder Systems, Reproducibility of Results |
| The association between delirium and the apolipoprotein E epsilon 4 allele: new study results and a meta-analysis. | van Munster BC, Korevaar JC, Zwinderman AH, Leeflang MM, de Rooij SE | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry | 2009 |
Activities of Daily Living, Age Factors, Aged, Aged, 80 and over, Alleles, Apolipoprotein E4, genetics, Cognition Disorders, complications, Delirium, complications, Female, Genotype, Geriatric Assessment, Humans, Male, Patients, psychology |
| Telephone interview for cognitive status: Creating a crosswalk with the Mini-Mental State Examination. | Fong TG, Fearing MA, Jones RN, Shi P, Marcantonio ER, Rudolph JL, Yang FM, Kiely DK, Inouye SK | Alzheimer's & dementia : the journal of the Alzheimer's Association | 2009 |
Aged, Aged, 80 and over, Alzheimer Disease, diagnosis, Cognition Disorders, diagnosis, Disability Evaluation, Female, Geriatric Assessment, methods, Health Status, Humans, Interviews as Topic, methods, Male, Mass Screening, methods, Models, Statistical, Neuropsychological Tests, Predictive Value of Tests, Psychiatric Status Rating Scales, Remote Consultation, methods, Reproducibility of Results, Sensitivity and Specificity |
| The role of genetics in delirium in the elderly patient. | van Munster BC, de Rooij SE, Korevaar JC | Dementia and geriatric cognitive disorders | 2009 |
Aged, psychology, Delirium, genetics, Genotype, Humans, Research |
| The evaluation of delirium post-stroke. | Mc Manus J, Pathansali R, Hassan H, Ouldred E, Cooper D, Stewart R, Macdonald A, Jackson S | International journal of geriatric psychiatry | 2009 |
Adult, Aged, Aged, 80 and over, Delirium, diagnosis, Female, Humans, Male, Middle Aged, Psychiatric Status Rating Scales, standards, Risk Assessment, Sensitivity and Specificity, Stroke, psychology, Young Adult |
| Assessment of the risk of postoperative delirium in elderly patients using E-PASS and the NEECHAM Confusion Scale. | Hattori H, Kamiya J, Shimada H, Akiyama H, Yasui A, Kuroiwa K, Oda K, Ando M, Kawamura T, Harada A, Kitagawa Y, Fukata S | International journal of geriatric psychiatry | 2009 |
Activities of Daily Living, Aged, Aged, 80 and over, Delirium, diagnosis, Female, Humans, Male, Postoperative Complications, diagnosis, Psychiatric Status Rating Scales, Quality of Life, Risk Factors |
| Prevalence of delirium with dexmedetomidine compared with morphine based therapy after cardiac surgery: a randomized controlled trial (DEXmedetomidine COmpared to Morphine-DEXCOM Study). | Shehabi Y, Grant P, Wolfenden H, Hammond N, Bass F, Campbell M, Chen J | Anesthesiology | 2009 |
Adrenergic alpha-Agonists, adverse effects, Aged, Analgesics, Opioid, adverse effects, Delirium, chemically induced, Dexmedetomidine, adverse effects, Double-Blind Method, Female, Humans, Hypnotics and Sedatives, adverse effects, Intensive Care Units, Intra-Aortic Balloon Pumping, Male, Morphine, adverse effects, Pain, Postoperative, drug therapy, Postoperative Care, Propofol, administration & dosage |
| Non-pharmacological interventions in the prevention of delirium. | Tabet N, Howard R | Age and ageing | 2009 |
Aged, Aged, 80 and over, Caregivers, education, Clinical Trials as Topic, Delirium, prevention & control, Humans, Randomized Controlled Trials as Topic, Risk Factors |
| Benzodiazepines for delirium. | Lonergan E, Luxenberg J, Areosa Sastre A | The Cochrane database of systematic reviews | 2009 |
Benzodiazepines, therapeutic use, Delirium, drug therapy, Dexmedetomidine, therapeutic use, Humans, Lorazepam, therapeutic use |
| Delirium accelerates cognitive decline in Alzheimer disease. | Fong TG, Jones RN, Shi P, Marcantonio ER, Yap L, Rudolph JL, Yang FM, Kiely DK, Inouye SK | Neurology | 2009 |
Age Distribution, Aged, Aged, 80 and over, Alzheimer Disease, epidemiology, Cognition Disorders, diagnosis, Cohort Studies, Comorbidity, Delirium, epidemiology, Disease Progression, Female, Humans, Incidence, Male, Massachusetts, Neuropsychological Tests, Prospective Studies, Registries, Sex Characteristics, Time Factors |
| Cytokines and IGF-I in delirious and non-delirious acutely ill older medical inpatients. | Adamis D, Lunn M, Martin FC, Treloar A, Gregson N, Hamilton G, Macdonald AJ | Age and ageing | 2009 |
APACHE, Acute Disease, Age Factors, Aged, Aged, 80 and over, Apolipoprotein E4, genetics, Biological Markers, blood, Cognition, Cytokines, blood, Delirium, blood, Female, Humans, Insulin-Like Growth Factor I, analysis, Interferon-gamma, blood, Interleukin 1 Receptor Antagonist Protein, blood, Longitudinal Studies, Male, Prospective Studies |
| Predicting the onset of delirium in the post-operative patient. | Noimark D | Age and ageing | 2009 |
Aged, Delirium, complications, Forecasting, Frail Elderly, Geriatric Assessment, Humans, Postoperative Complications, etiology, Preoperative Care, Risk Assessment, Risk Factors, Surgical Procedures, Operative, adverse effects |
| Measures of executive function and depression identify patients at risk for postoperative delirium. | Greene NH, Attix DK, Weldon BC, Smith PJ, McDonagh DL, Monk TG | Anesthesiology | 2009 |
Aged, Cognition, physiology, Cognition Disorders, complications, Cohort Studies, Delirium, diagnosis, Depression, complications, Female, Humans, Incidence, Male, Middle Aged, Neuropsychological Tests, Postoperative Complications, diagnosis, Predictive Value of Tests, Preoperative Care, Prospective Studies, Risk Factors, Surgical Procedures, Elective, adverse effects, Treatment Outcome |
| Executive function and depression as independent risk factors for postoperative delirium. | Smith PJ, Attix DK, Weldon BC, Greene NH, Monk TG | Anesthesiology | 2009 |
Adolescent, Adult, Aged, Aged, 80 and over, Cognition, physiology, Cognition Disorders, complications, Delirium, etiology, Depression, complications, Female, Humans, Male, Middle Aged, Postoperative Complications, Predictive Value of Tests, Retrospective Studies, Risk Factors, Surgical Procedures, Elective, adverse effects, Young Adult |
| Rivastigmine for the prevention of postoperative delirium in elderly patients undergoing elective cardiac surgery--a randomized controlled trial. | Gamberini M, Bolliger D, Lurati Buse GA, Burkhart CS, Grapow M, Gagneux A, Filipovic M, Seeberger MD, Pargger H, Siegemund M, Carrel T, Seiler WO, Berres M, Strebel SP, Monsch AU, Steiner LA | Critical care medicine | 2009 |
Administration, Oral, Age Factors, Aged, Aged, 80 and over, Cardiac Surgical Procedures, adverse effects, Cardiopulmonary Bypass, adverse effects, Delirium, epidemiology, Double-Blind Method, Drug Administration Schedule, Female, Follow-Up Studies, Humans, Incidence, Male, Mental Status Schedule, Neuroprotective Agents, administration & dosage, Phenylcarbamates, administration & dosage, Postoperative Complications, prevention & control, Preoperative Care, methods, Probability, Reference Values, Risk Assessment, Surgical Procedures, Elective, adverse effects, Treatment Outcome |
| Comparison of delirium assessment tools in a mixed intensive care unit. | van Eijk MM, van Marum RJ, Klijn IA, de Wit N, Kesecioglu J, Slooter AJ | Critical care medicine | 2009 |
Aged, Delirium, diagnosis, Diagnostic Techniques, Neurological, Female, Humans, Intensive Care Units, Male, Middle Aged, Prospective Studies |
| The impact of delirium on clinical outcomes in mechanically ventilated surgical and trauma patients. | Lat I, McMillian W, Taylor S, Janzen JM, Papadopoulos S, Korth L, Ehtisham A, Nold J, Agarwal S, Azocar R, Burke P | Critical care medicine | 2009 |
Adult, Aged, Critical Illness, Delirium, epidemiology, Female, Humans, Incidence, Male, Middle Aged, Postoperative Complications, epidemiology, Prospective Studies, Respiration, Artificial, Risk Factors, Wounds and Injuries, complications |
| The course of delirium in acute stroke. | McManus J, Pathansali R, Hassan H, Ouldred E, Cooper D, Stewart R, Macdonald A, Jackson S | Age and ageing | 2009 |
Algorithms, Delirium, diagnosis, Female, Follow-Up Studies, Hospitalization, Humans, Logistic Models, Male, Odds Ratio, Outcome Assessment (Health Care), Postoperative Complications, epidemiology, Prevalence, Prognosis, Prospective Studies, Regression Analysis, Risk Factors, Severity of Illness Index, Stroke, complications |
| Geriatric ward hospitalization reduced incidence delirium among older medical inpatients. | Bo M, Martini B, Ruatta C, Massaia M, Ricauda NA, Varetto A, Astengo M, Torta R | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry | 2009 |
Aged, Aged, 80 and over, Delirium, epidemiology, Female, Geriatric Assessment, Geriatrics, Hospital Units, Hospitalization, statistics & numerical data, Hospitals, University, Humans, Incidence, Inpatients, Italy, epidemiology, Male, Prognosis, Prospective Studies, Questionnaires, Risk Factors |
| Occurrence of delirium is severely underestimated in the ICU during daily care. | Spronk PE, Riekerk B, Hofhuis J, Rommes JH | Intensive care medicine | 2009 |
Aged, Aged, 80 and over, Critical Illness, nursing, Delirium, diagnosis, Female, Hospital Mortality, Hospitalists, Hospitals, Teaching, Humans, Intensive Care Units, Male, Mass Screening, instrumentation, Middle Aged, Netherlands, epidemiology, Nurses, Physicians |
| Improving the outcomes of delirium in older hospital inpatients. | Cole MG, McCusker J | International psychogeriatrics / IPA | 2009 |
Activities of Daily Living, classification, Aged, Cognition Disorders, diagnosis, Delirium, diagnosis, Follow-Up Studies, Hospitalization, Humans, Institutionalization, statistics & numerical data, Outcome Assessment (Health Care), statistics & numerical data, Patient Discharge, Treatment Failure |
| Does postoperative delirium limit the use of patient-controlled analgesia in older surgical patients? | Leung JM, Sands LP, Paul S, Joseph T, Kinjo S, Tsai T | Anesthesiology | 2009 |
Aged, Aged, 80 and over, Analgesia, Patient-Controlled, Analgesics, Opioid, administration & dosage, Delirium, psychology, Female, Humans, Hydromorphone, administration & dosage, Male, Orthopedic Procedures, Pain Measurement, Pain, Postoperative, drug therapy, Postoperative Complications, psychology, Psychiatric Status Rating Scales, Reproducibility of Results |
| Impact of delirium on short-term mortality in elderly inpatients: a prospective cohort study. | González M, Martínez G, Calderón J, Villarroel L, Yuri F, Rojas C, Jeria A, Valdivia G, Marín PP, Carrasco M | Psychosomatics | 2009 |
APACHE, Aged, Aged, 80 and over, Chile, Cohort Studies, Comorbidity, Cross-Sectional Studies, Delirium, diagnosis, Diagnostic and Statistical Manual of Mental Disorders, Female, Follow-Up Studies, Hospitals, University, Humans, Length of Stay, Male, Neuropsychological Tests, Prospective Studies, Referral and Consultation |
| Proteomic profiling of plasma and serum in elderly patients with delirium. | van Munster BC, van Breemen MJ, Moerland PD, Speijer D, De Rooij SE, Pfrommer CJ, Levi M, Hollmann MW, Aerts JM, Zwinderman AH, Korevaar JC | The Journal of neuropsychiatry and clinical neurosciences | 2009 |
Aged, 80 and over, Delirium, blood, Female, Hemoglobins, metabolism, Hip Fractures, blood, Humans, Male, Mass Spectrometry, Protein Array Analysis, Psychiatric Status Rating Scales, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Time Factors |
| Dexmedetomidine and the reduction of postoperative delirium after cardiac surgery. | Maldonado JR, Wysong A, van der Starre PJ, Block T, Miller C, Reitz BA | Psychosomatics | 2009 |
Adult, Aged, Cardiopulmonary Bypass, Delirium, chemically induced, Dexmedetomidine, adverse effects, Dose-Response Relationship, Drug, Drug Administration Schedule, Female, Follow-Up Studies, Heart Valve Diseases, surgery, Heart Valve Prosthesis Implantation, Humans, Hypnotics and Sedatives, adverse effects, Intensive Care Units, Male, Midazolam, adverse effects, Middle Aged, Neuropsychological Tests, Postoperative Complications, diagnosis, Propofol, adverse effects |
| Proinflammatory cytokines, sickness behavior, and Alzheimer disease. | Holmes C, Cunningham C, Zotova E, Culliford D, Perry VH | Neurology | 2011 |
Aged, 80 and over, Alzheimer Disease, blood, C-Reactive Protein, metabolism, Chi-Square Distribution, Cohort Studies, Cytokines, blood, Delirium, etiology, Female, Humans, Illness Behavior, physiology, Male, Neuropsychological Tests, Psychiatric Status Rating Scales, Residence Characteristics, Retrospective Studies |
| Bedside nurse-patient interactions do not reliably detect delirium: an observational study. | Mistarz R, Eliott S, Whitfield A, Ernest D | Australian critical care : official journal of the Confederation of Australian Critical Care Nurses | 2011 |
APACHE, Adult, Aged, Aged, 80 and over, Delirium, diagnosis, Female, Hospitals, University, Humans, Intensive Care Units, Male, Middle Aged, Nurse-Patient Relations, Nursing Assessment, Observation, Predictive Value of Tests, Sensitivity and Specificity |
| Individual risk profiles for postoperative delirium after joint replacement surgery. | Jain FA, Brooks JO, Larsen KA, Kelly SE, Bode RH, Sweeney GA, Stern TA | Psychosomatics | 2011 |
Age Factors, Aged, Analgesics, Opioid, adverse effects, Antipsychotic Agents, therapeutic use, Arthroplasty, Replacement, adverse effects, Benzodiazepines, therapeutic use, Delirium, etiology, Double-Blind Method, Hematocrit, Humans, Male, Morphine, adverse effects, Postoperative Complications, prevention & control, Risk Factors, Signal Detection, Psychological |
| Primitive reflexes associated with delirium: a prospective trial. | Nicolson SE, Chabon B, Larsen KA, Kelly SE, Potter AW, Stern TA | Psychosomatics | 2011 |
Aged, Aged, 80 and over, Cognition Disorders, epidemiology, Delirium, epidemiology, Female, Frontal Lobe, physiopathology, Humans, Incidence, Male, Middle Aged, Postoperative Complications, epidemiology, Preoperative Care, methods, Prognosis, Prospective Studies, Reflex, Abnormal, physiology, Risk Factors, Young Adult |
| A discursive exploration of the practices that shape and discipline nurses' responses to postoperative delirium. | Kjorven M, Rush K, Hole R | Nursing inquiry | 2011 |
Adult, Aged, Attitude of Health Personnel, Delirium, nursing, Female, Humans, Male, Middle Aged, Nurse’s Practice Patterns, Nursing Methodology Research, Nursing Staff, Hospital, psychology, Nursing Theory, Postoperative Care, nursing, Young Adult |
| Comparative efficacy study of haloperidol, olanzapine and risperidone in delirium. | Grover S, Kumar V, Chakrabarti S | Journal of psychosomatic research | 2011 |
Adult, Aged, Antipsychotic Agents, administration & dosage, Benzodiazepines, administration & dosage, Delirium, drug therapy, Drug Administration Schedule, Female, Follow-Up Studies, Haloperidol, administration & dosage, Humans, Male, Middle Aged, Risperidone, administration & dosage, Single-Blind Method, Treatment Outcome |
| Subsyndromal delirium in older long-term care residents: incidence, risk factors, and outcomes. | Cole MG, McCusker J, Voyer P, Monette J, Champoux N, Ciampi A, Vu M, Belzile E | Journal of the American Geriatrics Society | 2011 |
Aged, Aged, 80 and over, Alzheimer Disease, diagnosis, Cohort Studies, Comorbidity, Cross-Sectional Studies, Delirium, diagnosis, Dementia, diagnosis, Dementia, Vascular, diagnosis, Female, Follow-Up Studies, Geriatric Assessment, Health Surveys, Humans, Incidence, Long-Term Care, statistics & numerical data, Male, Mental Status Schedule, Multivariate Analysis, Quebec, Risk Factors |
| Effects of multidisciplinary integrated care on quality of care in residential care facilities for elderly people: a cluster randomized trial. | Boorsma M, Frijters DH, Knol DL, Ribbe ME, Nijpels G, van Hout HP | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne | 2011 |
Aged, Aged, 80 and over, Disease Management, Female, Geriatric Assessment, Humans, Male, Netherlands, Patient Care Team, Patient-Centered Care, Quality Indicators, Health Care, Quality of Health Care, Quality of Life, Residential Facilities |
| The validity and reliability of the Portuguese versions of three tools used to diagnose delirium in critically ill patients. | Gusmao-Flores D, Salluh JI, Dal-Pizzol F, Ritter C, Tomasi CD, Lima MA, Santana LR, Lins RM, Lemos PP, Serpa GV, Oliveira J, Chalhub RÁ, Pitrowsky MT, Lacerda AL, Koenen KC, Quarantini LC | Clinics (São Paulo, Brazil) | 2011 |
Brazil, Critical Illness, Delirium, diagnosis, Female, Humans, Intensive Care Units, Language, Male, Mass Screening, adverse effects, Middle Aged, Reproducibility of Results, Sensitivity and Specificity, Translations |
| Postoperative opioid consumption and its relationship to cognitive function in older adults with hip fracture. | Sieber FE, Mears S, Lee H, Gottschalk A | Journal of the American Geriatrics Society | 2011 |
Aged, 80 and over, Analgesics, Opioid, adverse effects, Cognition Disorders, chemically induced, Female, Hip Fractures, surgery, Humans, Male, Pain, Postoperative, drug therapy, Prospective Studies |
| Pilot randomized trial of donepezil hydrochloride for delirium after hip fracture. | Marcantonio ER, Palihnich K, Appleton P, Davis RB | Journal of the American Geriatrics Society | 2011 |
Aged, Aged, 80 and over, Cholinesterase Inhibitors, therapeutic use, Delirium, drug therapy, Double-Blind Method, Female, Hip Fractures, surgery, Humans, Indans, therapeutic use, Male, Pilot Projects, Piperidines, therapeutic use, Postoperative Complications, drug therapy, Prospective Studies |
| Precipitating factors associated with delirium among long-term care residents with dementia. | Voyer P, Richard S, Doucet L, Cyr N, Carmichael PH | Applied nursing research : ANR | 2011 |
Cross-Sectional Studies, Delirium, complications, Dementia, complications, Humans, Long-Term Care, Nursing Homes, organization & administration, Quebec |
| Outcome in hip fracture patients related to anemia at admission and allogeneic blood transfusion: an analysis of 1262 surgically treated patients. | Vochteloo AJ, Borger van der Burg BL, Mertens B, Niggebrugge AH, de Vries MR, Tuinebreijer WE, Bloem RM, Nelissen RG, Pilot P | BMC musculoskeletal disorders | 2011 |
Aged, Aged, 80 and over, Anemia, mortality, Blood Transfusion, Autologous, adverse effects, Cohort Studies, Comorbidity, Female, Hip Fractures, mortality, Humans, Male, Netherlands, epidemiology, Prospective Studies |
| Risk factors for postoperative cognitive and functional difficulties in abdominal aortic aneurysm patients: a three month follow-up. | Wallbridge HR, Benoit AG, Staley D, Ediger JP, Campbell BI | International journal of geriatric psychiatry | 2011 |
Adult, Aged, Aged, 80 and over, Aortic Aneurysm, Abdominal, surgery, Cognition, physiology, Cognition Disorders, epidemiology, Delirium, epidemiology, Epidemiologic Methods, Female, Humans, Male, Middle Aged, Postoperative Complications, epidemiology, Risk Factors |
| A review of recent clinical trials and guidelines on the prevention and management of delirium in hospitalized older patients. | Rathier MO, Baker WL | Hospital practice (1995) | 2011 |
Aged, Aged, 80 and over, Analgesics, therapeutic use, Antipsychotic Agents, therapeutic use, Cholinesterase Inhibitors, therapeutic use, Clinical Trials as Topic, Delirium, diagnosis, Diagnosis, Differential, Geriatric Assessment, Humans, Hypnotics and Sedatives, therapeutic use, Inpatients, Intensive Care Units, Practice Guidelines as Topic, Risk Factors |
| Systemic inflammation and delirium: important co-factors in the progression of dementia. | Cunningham C | Biochemical Society transactions | 2011 |
Animals, Anti-Inflammatory Agents, Non-Steroidal, therapeutic use, Central Nervous System, physiopathology, Delirium, complications, Dementia, complications, Disease Progression, Humans, Inflammation, complications |