What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Exercise for acutely hospitalised older medical patients
- Authors
- Hartley, P. Keating, J. L. Jeffs, K. J. Raymond, M. J. Smith, T. O
- Year
- 2022
- Journal
- Cochrane Database Syst Rev
- Abstract
BACKGROUND: Approximately 30% of hospitalised older adults experience hospital-associated functional decline. Exercise interventions that promote in-hospital activity may prevent deconditioning and thereby maintain physical function during hospitalisation. This is an update of a Cochrane Review first published in 2007. OBJECTIVES: To evaluate the benefits and harms of exercise interventions for acutely hospitalised older medical inpatients on functional ability, quality of life (QoL), participant global assessment of success and adverse events compared to usual care or a sham-control intervention. SEARCH METHODS: We used standard, extensive Cochrane search methods. The latest search date was May 2021. SELECTION CRITERIA: We included randomised or quasi-randomised controlled trials evaluating an in-hospital exercise intervention in people aged 65 years or older admitted to hospital with a general medical condition. We excluded people admitted for elective reasons or surgery. DATA COLLECTION AND ANALYSIS: We used standard Cochrane methods. Our major outcomes were 1. independence with activities of daily living; 2. functional mobility; 3. new incidence of delirium during hospitalisation; 4. QoL; 5. number of falls during hospitalisation; 6. medical deterioration during hospitalisation and 7. participant global assessment of success. Our minor outcomes were 8. death during hospitalisation; 9. musculoskeletal injuries during hospitalisation; 10. hospital length of stay; 11. new institutionalisation at hospital discharge; 12. hospital readmission and 13. walking performance. We used GRADE to assess certainty of evidence for each major outcome. We categorised exercise interventions as: rehabilitation-related activities (interventions designed to increase physical activity or functional recovery, but did not follow a specified exercise protocol); structured exercise (interventions that included an exercise intervention protocol but did not include progressive resistance training); and progressive resistance exercise (interventions that included an element of progressive resistance training). MAIN RESULTS: We included 24 studies (nine rehabilitation-related activity interventions, six structured exercise interventions and nine progressive resistance exercise interventions) with 7511 participants. All studies compared exercise interventions to usual care; two studies, in addition to usual care, used sham interventions. Mean ages ranged from 73 to 88 years, and 58% of participants were women. Several studies were at high risk of bias. The most common domain assessed at high risk of bias was measurement of the outcome, and five studies (21%) were at high risk of bias arising from the randomisation process. Exercise may have no clinically important effect on independence in activities of daily living at discharge from hospital compared to controls (16 studies, 5174 participants; low-certainty evidence). Five studies used the Barthel Index (scale: 0 to 100, higher scores representing greater independence). Mean scores at discharge in the control groups ranged from 42 to 96 points, and independence in activities of daily living was 1.8 points better (0.43 worse to 4.12 better) with exercise compared to controls. The minimally clinical important difference (MCID) is estimated to be 11 points. We are uncertain regarding the effect of exercise on functional mobility at discharge from the hospital compared to controls (8 studies, 2369 participants; very low-certainty evidence). Three studies used the Short Physical Performance Battery (SPPB) (scale: 0 to 12, higher scores representing better function) to measure functional mobility. Mean scores at discharge in the control groups ranged from 3.7 to 4.9 points on the SPPB, and the estimated effect of the exercise interventions was 0.78 points better (0.02 worse to 1.57 better). A change of 1 point on the SPPB represents an MCID. We are uncertain regarding the effect of exercise on the incidence of delirium during hospitalisation compared to controls (7 trials, 2088 participants; very low-certainty evidence). The incidence of delirium during hospitalisation was 88/1091 (81 per 1000) in the control group compared with 70/997 (73 per 1000; range 47 to 114) in the exercise group (RR 0.90, 95% CI 0.58 to 1.41). Exercise interventions may result in a small clinically unimportant improvement in QoL at discharge from the hospital compared to controls (4 studies, 875 participants; low-certainty evidence). Mean QoL on the EuroQol 5 Dimensions (EQ-5D) visual analogue scale (VAS) (scale: 0 to 100, higher scores representing better QoL) ranged between 48.9 and 64.7 in the control group at discharge from the hospital, and QoL was 6.04 points better (0.9 better to 11.18 better) with exercise. A change of 10 points on the EQ-5D VAS represents an MCID. No studies measured participant global assessment of success. Exercise interventions did not affect the risk of falls during hospitalisation (moderate-certainty evidence). The incidence of falls was 31/899 (34 per 1000) in the control group compared with 31/888 (34 per 1000; range 20 to 57) in the exercise group (RR 0.99, 95% CI 0.59 to 1.65). We are uncertain regarding the effect of exercise on the incidence of medical deterioration during hospitalisation (very low-certainty evidence). The incidence of medical deterioration in the control group was 101/1417 (71 per 1000) compared with 96/1313 (73 per 1000; range 44 to 120) in the exercise group (RR 1.02, 95% CI 0.62 to 1.68). Subgroup analyses by different intervention categories and by the use of a sham intervention were not meaningfully different from the main analyses. AUTHORS’ CONCLUSIONS: Exercise may make little difference to independence in activities of daily living or QoL, but probably does not result in more falls in older medical inpatients. We are uncertain about the effect of exercise on functional mobility, incidence of delirium and medical deterioration. Certainty of evidence was limited by risk of bias and inconsistency. Future primary research on the effect of exercise on acute hospitalisation could focus on more consistent and uniform reporting of participant’s characteristics including their baseline level of functional ability, as well as exercise dose, intensity and adherence that may provide an insight into the reasons for the observed inconsistencies in findings.
- PMID
- Keywords
Aged
Aged, 80 and over
Female
Humans
Male
Activities of Daily Living
*Delirium/epidemiology
Exercise
*Quality of Life
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| The course of delirium in acute stroke. | McManus J, Pathansali R, Hassan H, Ouldred E, Cooper D, Stewart R, Macdonald A, Jackson S | Age and ageing | 2009 |
Algorithms, Delirium, diagnosis, Female, Follow-Up Studies, Hospitalization, Humans, Logistic Models, Male, Odds Ratio, Outcome Assessment (Health Care), Postoperative Complications, epidemiology, Prevalence, Prognosis, Prospective Studies, Regression Analysis, Risk Factors, Severity of Illness Index, Stroke, complications |
| Geriatric ward hospitalization reduced incidence delirium among older medical inpatients. | Bo M, Martini B, Ruatta C, Massaia M, Ricauda NA, Varetto A, Astengo M, Torta R | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry | 2009 |
Aged, Aged, 80 and over, Delirium, epidemiology, Female, Geriatric Assessment, Geriatrics, Hospital Units, Hospitalization, statistics & numerical data, Hospitals, University, Humans, Incidence, Inpatients, Italy, epidemiology, Male, Prognosis, Prospective Studies, Questionnaires, Risk Factors |
| Occurrence of delirium is severely underestimated in the ICU during daily care. | Spronk PE, Riekerk B, Hofhuis J, Rommes JH | Intensive care medicine | 2009 |
Aged, Aged, 80 and over, Critical Illness, nursing, Delirium, diagnosis, Female, Hospital Mortality, Hospitalists, Hospitals, Teaching, Humans, Intensive Care Units, Male, Mass Screening, instrumentation, Middle Aged, Netherlands, epidemiology, Nurses, Physicians |
| Improving the outcomes of delirium in older hospital inpatients. | Cole MG, McCusker J | International psychogeriatrics / IPA | 2009 |
Activities of Daily Living, classification, Aged, Cognition Disorders, diagnosis, Delirium, diagnosis, Follow-Up Studies, Hospitalization, Humans, Institutionalization, statistics & numerical data, Outcome Assessment (Health Care), statistics & numerical data, Patient Discharge, Treatment Failure |
| Does postoperative delirium limit the use of patient-controlled analgesia in older surgical patients? | Leung JM, Sands LP, Paul S, Joseph T, Kinjo S, Tsai T | Anesthesiology | 2009 |
Aged, Aged, 80 and over, Analgesia, Patient-Controlled, Analgesics, Opioid, administration & dosage, Delirium, psychology, Female, Humans, Hydromorphone, administration & dosage, Male, Orthopedic Procedures, Pain Measurement, Pain, Postoperative, drug therapy, Postoperative Complications, psychology, Psychiatric Status Rating Scales, Reproducibility of Results |
| Impact of delirium on short-term mortality in elderly inpatients: a prospective cohort study. | González M, Martínez G, Calderón J, Villarroel L, Yuri F, Rojas C, Jeria A, Valdivia G, Marín PP, Carrasco M | Psychosomatics | 2009 |
APACHE, Aged, Aged, 80 and over, Chile, Cohort Studies, Comorbidity, Cross-Sectional Studies, Delirium, diagnosis, Diagnostic and Statistical Manual of Mental Disorders, Female, Follow-Up Studies, Hospitals, University, Humans, Length of Stay, Male, Neuropsychological Tests, Prospective Studies, Referral and Consultation |
| Proteomic profiling of plasma and serum in elderly patients with delirium. | van Munster BC, van Breemen MJ, Moerland PD, Speijer D, De Rooij SE, Pfrommer CJ, Levi M, Hollmann MW, Aerts JM, Zwinderman AH, Korevaar JC | The Journal of neuropsychiatry and clinical neurosciences | 2009 |
Aged, 80 and over, Delirium, blood, Female, Hemoglobins, metabolism, Hip Fractures, blood, Humans, Male, Mass Spectrometry, Protein Array Analysis, Psychiatric Status Rating Scales, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Time Factors |
| Dexmedetomidine and the reduction of postoperative delirium after cardiac surgery. | Maldonado JR, Wysong A, van der Starre PJ, Block T, Miller C, Reitz BA | Psychosomatics | 2009 |
Adult, Aged, Cardiopulmonary Bypass, Delirium, chemically induced, Dexmedetomidine, adverse effects, Dose-Response Relationship, Drug, Drug Administration Schedule, Female, Follow-Up Studies, Heart Valve Diseases, surgery, Heart Valve Prosthesis Implantation, Humans, Hypnotics and Sedatives, adverse effects, Intensive Care Units, Male, Midazolam, adverse effects, Middle Aged, Neuropsychological Tests, Postoperative Complications, diagnosis, Propofol, adverse effects |
| Proinflammatory cytokines, sickness behavior, and Alzheimer disease. | Holmes C, Cunningham C, Zotova E, Culliford D, Perry VH | Neurology | 2011 |
Aged, 80 and over, Alzheimer Disease, blood, C-Reactive Protein, metabolism, Chi-Square Distribution, Cohort Studies, Cytokines, blood, Delirium, etiology, Female, Humans, Illness Behavior, physiology, Male, Neuropsychological Tests, Psychiatric Status Rating Scales, Residence Characteristics, Retrospective Studies |
| Bedside nurse-patient interactions do not reliably detect delirium: an observational study. | Mistarz R, Eliott S, Whitfield A, Ernest D | Australian critical care : official journal of the Confederation of Australian Critical Care Nurses | 2011 |
APACHE, Adult, Aged, Aged, 80 and over, Delirium, diagnosis, Female, Hospitals, University, Humans, Intensive Care Units, Male, Middle Aged, Nurse-Patient Relations, Nursing Assessment, Observation, Predictive Value of Tests, Sensitivity and Specificity |
| Individual risk profiles for postoperative delirium after joint replacement surgery. | Jain FA, Brooks JO, Larsen KA, Kelly SE, Bode RH, Sweeney GA, Stern TA | Psychosomatics | 2011 |
Age Factors, Aged, Analgesics, Opioid, adverse effects, Antipsychotic Agents, therapeutic use, Arthroplasty, Replacement, adverse effects, Benzodiazepines, therapeutic use, Delirium, etiology, Double-Blind Method, Hematocrit, Humans, Male, Morphine, adverse effects, Postoperative Complications, prevention & control, Risk Factors, Signal Detection, Psychological |
| Primitive reflexes associated with delirium: a prospective trial. | Nicolson SE, Chabon B, Larsen KA, Kelly SE, Potter AW, Stern TA | Psychosomatics | 2011 |
Aged, Aged, 80 and over, Cognition Disorders, epidemiology, Delirium, epidemiology, Female, Frontal Lobe, physiopathology, Humans, Incidence, Male, Middle Aged, Postoperative Complications, epidemiology, Preoperative Care, methods, Prognosis, Prospective Studies, Reflex, Abnormal, physiology, Risk Factors, Young Adult |
| A discursive exploration of the practices that shape and discipline nurses' responses to postoperative delirium. | Kjorven M, Rush K, Hole R | Nursing inquiry | 2011 |
Adult, Aged, Attitude of Health Personnel, Delirium, nursing, Female, Humans, Male, Middle Aged, Nurse’s Practice Patterns, Nursing Methodology Research, Nursing Staff, Hospital, psychology, Nursing Theory, Postoperative Care, nursing, Young Adult |
| Comparative efficacy study of haloperidol, olanzapine and risperidone in delirium. | Grover S, Kumar V, Chakrabarti S | Journal of psychosomatic research | 2011 |
Adult, Aged, Antipsychotic Agents, administration & dosage, Benzodiazepines, administration & dosage, Delirium, drug therapy, Drug Administration Schedule, Female, Follow-Up Studies, Haloperidol, administration & dosage, Humans, Male, Middle Aged, Risperidone, administration & dosage, Single-Blind Method, Treatment Outcome |
| Subsyndromal delirium in older long-term care residents: incidence, risk factors, and outcomes. | Cole MG, McCusker J, Voyer P, Monette J, Champoux N, Ciampi A, Vu M, Belzile E | Journal of the American Geriatrics Society | 2011 |
Aged, Aged, 80 and over, Alzheimer Disease, diagnosis, Cohort Studies, Comorbidity, Cross-Sectional Studies, Delirium, diagnosis, Dementia, diagnosis, Dementia, Vascular, diagnosis, Female, Follow-Up Studies, Geriatric Assessment, Health Surveys, Humans, Incidence, Long-Term Care, statistics & numerical data, Male, Mental Status Schedule, Multivariate Analysis, Quebec, Risk Factors |
| Effects of multidisciplinary integrated care on quality of care in residential care facilities for elderly people: a cluster randomized trial. | Boorsma M, Frijters DH, Knol DL, Ribbe ME, Nijpels G, van Hout HP | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne | 2011 |
Aged, Aged, 80 and over, Disease Management, Female, Geriatric Assessment, Humans, Male, Netherlands, Patient Care Team, Patient-Centered Care, Quality Indicators, Health Care, Quality of Health Care, Quality of Life, Residential Facilities |
| The validity and reliability of the Portuguese versions of three tools used to diagnose delirium in critically ill patients. | Gusmao-Flores D, Salluh JI, Dal-Pizzol F, Ritter C, Tomasi CD, Lima MA, Santana LR, Lins RM, Lemos PP, Serpa GV, Oliveira J, Chalhub RÁ, Pitrowsky MT, Lacerda AL, Koenen KC, Quarantini LC | Clinics (São Paulo, Brazil) | 2011 |
Brazil, Critical Illness, Delirium, diagnosis, Female, Humans, Intensive Care Units, Language, Male, Mass Screening, adverse effects, Middle Aged, Reproducibility of Results, Sensitivity and Specificity, Translations |
| Postoperative opioid consumption and its relationship to cognitive function in older adults with hip fracture. | Sieber FE, Mears S, Lee H, Gottschalk A | Journal of the American Geriatrics Society | 2011 |
Aged, 80 and over, Analgesics, Opioid, adverse effects, Cognition Disorders, chemically induced, Female, Hip Fractures, surgery, Humans, Male, Pain, Postoperative, drug therapy, Prospective Studies |
| Pilot randomized trial of donepezil hydrochloride for delirium after hip fracture. | Marcantonio ER, Palihnich K, Appleton P, Davis RB | Journal of the American Geriatrics Society | 2011 |
Aged, Aged, 80 and over, Cholinesterase Inhibitors, therapeutic use, Delirium, drug therapy, Double-Blind Method, Female, Hip Fractures, surgery, Humans, Indans, therapeutic use, Male, Pilot Projects, Piperidines, therapeutic use, Postoperative Complications, drug therapy, Prospective Studies |
| Precipitating factors associated with delirium among long-term care residents with dementia. | Voyer P, Richard S, Doucet L, Cyr N, Carmichael PH | Applied nursing research : ANR | 2011 |
Cross-Sectional Studies, Delirium, complications, Dementia, complications, Humans, Long-Term Care, Nursing Homes, organization & administration, Quebec |
| Outcome in hip fracture patients related to anemia at admission and allogeneic blood transfusion: an analysis of 1262 surgically treated patients. | Vochteloo AJ, Borger van der Burg BL, Mertens B, Niggebrugge AH, de Vries MR, Tuinebreijer WE, Bloem RM, Nelissen RG, Pilot P | BMC musculoskeletal disorders | 2011 |
Aged, Aged, 80 and over, Anemia, mortality, Blood Transfusion, Autologous, adverse effects, Cohort Studies, Comorbidity, Female, Hip Fractures, mortality, Humans, Male, Netherlands, epidemiology, Prospective Studies |
| Risk factors for postoperative cognitive and functional difficulties in abdominal aortic aneurysm patients: a three month follow-up. | Wallbridge HR, Benoit AG, Staley D, Ediger JP, Campbell BI | International journal of geriatric psychiatry | 2011 |
Adult, Aged, Aged, 80 and over, Aortic Aneurysm, Abdominal, surgery, Cognition, physiology, Cognition Disorders, epidemiology, Delirium, epidemiology, Epidemiologic Methods, Female, Humans, Male, Middle Aged, Postoperative Complications, epidemiology, Risk Factors |
| A review of recent clinical trials and guidelines on the prevention and management of delirium in hospitalized older patients. | Rathier MO, Baker WL | Hospital practice (1995) | 2011 |
Aged, Aged, 80 and over, Analgesics, therapeutic use, Antipsychotic Agents, therapeutic use, Cholinesterase Inhibitors, therapeutic use, Clinical Trials as Topic, Delirium, diagnosis, Diagnosis, Differential, Geriatric Assessment, Humans, Hypnotics and Sedatives, therapeutic use, Inpatients, Intensive Care Units, Practice Guidelines as Topic, Risk Factors |
| Systemic inflammation and delirium: important co-factors in the progression of dementia. | Cunningham C | Biochemical Society transactions | 2011 |
Animals, Anti-Inflammatory Agents, Non-Steroidal, therapeutic use, Central Nervous System, physiopathology, Delirium, complications, Dementia, complications, Disease Progression, Humans, Inflammation, complications |
| Geriatric conditions in acutely hospitalized older patients: prevalence and one-year survival and functional decline. | Buurman BM, Hoogerduijn JG, de Haan RJ, Abu-Hanna A, Lagaay AM, Verhaar HJ, Schuurmans MJ, Levi M, de Rooij SE | PloS one | 2011 |
Aged, Cohort Studies, Follow-Up Studies, Geriatrics, statistics & numerical data, Hospitalization, statistics & numerical data, Humans, Male, Patient Discharge, statistics & numerical data, Prevalence, Prognosis, Prospective Studies, Survival Analysis |
| Vulnerability: the crossroads of frailty and delirium. | Quinlan N, Marcantonio ER, Inouye SK, Gill TM, Kamholz B, Rudolph JL | Journal of the American Geriatrics Society | 2011 |
Aged, Delirium, diagnosis, Frail Elderly, Humans, Risk Factors |
| Development of a unidimensional composite measure of neuropsychological functioning in older cardiac surgery patients with good measurement precision. | Jones RN, Rudolph JL, Inouye SK, Yang FM, Fong TG, Milberg WP, Tommet D, Metzger ED, Cupples LA, Marcantonio ER | Journal of clinical and experimental neuropsychology | 2010 |
Aged, Aged, 80 and over, Cardiac Surgical Procedures, psychology, Coronary Artery Bypass, psychology, Factor Analysis, Statistical, Female, Humans, Longitudinal Studies, Male, Middle Aged, Models, Statistical, Neuropsychological Tests, Prospective Studies, Psychometrics, Questionnaires, Reproducibility of Results |
| A volunteer-based Hospital Elder Life Program to reduce delirium. | Sandhaus S, Zalon ML, Valenti D, Dzielak E, Smego RA, Arzamasova U | The health care manager | 2010 |
Aged, Attitude of Health Personnel, Clinical Competence, Cost-Benefit Analysis, Delirium, prevention & control, Geriatric Nursing, education, Geriatrics, education, Hospital Volunteers, education, Hospitals, Community, Humans, Inservice Training, organization & administration, Job Satisfaction, Models, Organizational, Nursing Staff, Hospital, psychology, Patient Care Team, Pennsylvania, Professional Role, Program Development, Program Evaluation |
| Delirium: a cognitive cost of the comfort of procedural sedation in elderly patients? | Crosby G, Culley DJ, Marcantonio ER | Mayo Clinic proceedings | 2010 |
Aged, Conscious Sedation, adverse effects, Deep Sedation, adverse effects, Delirium, chemically induced, Hip Fractures, surgery, Humans, Randomized Controlled Trials as Topic |
| Aging, brain disease, and reserve: implications for delirium. | Jones RN, Fong TG, Metzger E, Tulebaev S, Yang FM, Alsop DC, Marcantonio ER, Cupples LA, Gottlieb G, Inouye SK | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry | 2010 |
Adaptation, Psychological, Aging, psychology, Brain Diseases, complications, Cognition Disorders, psychology, Delirium, complications, Humans, Mental Disorders, complications, Neuronal Plasticity, Risk Factors |
| Hospitalization in community-dwelling persons with Alzheimer's disease: frequency and causes. | Rudolph JL, Zanin NM, Jones RN, Marcantonio ER, Fong TG, Yang FM, Yap L, Inouye SK | Journal of the American Geriatrics Society | 2010 |
Accidental Falls, statistics & numerical data, Age Factors, Aged, Alzheimer Disease, epidemiology, Comorbidity, Delirium, epidemiology, Female, Gastrointestinal Diseases, epidemiology, Hospitalization, statistics & numerical data, Humans, Longitudinal Studies, Male, Massachusetts, epidemiology, Myocardial Ischemia, epidemiology, Pneumonia, epidemiology, Prospective Studies, Registries, Risk Factors, Sex Factors, Syncope, epidemiology |
| Assessment of role of perioperative melatonin in prevention and treatment of postoperative delirium after hip arthroplasty under spinal anesthesia in the elderly. | Sultan SS | Saudi journal of anaesthesia | 2010 |
Postoperative delirium melatonin hip arthroplasty spinal anesthesia |
| Feasibility, efficacy, and safety of antipsychotics for intensive care unit delirium: the MIND randomized, placebo-controlled trial. | Girard TD, Pandharipande PP, Carson SS, Schmidt GA, Wright PE, Canonico AE, Pun BT, Thompson JL, Shintani AK, Meltzer HY, Bernard GR, Dittus RS, Ely EW, | Critical care medicine | 2010 |
Adult, Aged, Antipsychotic Agents, adverse effects, Delirium, drug therapy, Double-Blind Method, Female, Haloperidol, adverse effects, Humans, Intensive Care Units, Length of Stay, Male, Middle Aged, Piperazines, adverse effects, Postoperative Complications, psychology, Psychiatric Status Rating Scales, Respiration, Artificial, adverse effects, Thiazoles, adverse effects, Treatment Outcome |
| The association of the dopamine transporter gene and the dopamine receptor 2 gene with delirium, a meta-analysis. | van Munster BC, de Rooij SE, Yazdanpanah M, Tienari PJ, Pitkälä KH, Osse RJ, Adamis D, Smit O, van der Steen MS, van Houten M, Rahkonen T, Sulkava R, Laurila JV, Strandberg TE, Tulen JH, Zwang L, MacDonald AJ, Treloar A, Sijbrands EJ, Zwinderman AH, Kor | American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics | 2010 |
Aged, Aged, 80 and over, Cohort Studies, Delirium, genetics, Dopamine Plasma Membrane Transport Proteins, genetics, Europe, Female, Genetic Variation, Homozygote, Humans, Male, Models, Genetic, Polymorphism, Single Nucleotide, Receptors, Dopamine D2, genetics |
| Postoperative psychiatric disorders in general thoracic surgery: incidence, risk factors and outcomes. | Ozyurtkan MO, Yildizeli B, Kuşçu K, Bekiroğlu N, Bostanci K, Batirel HF, Yüksel M | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery | 2010 |
Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Biological Markers, blood, Female, Humans, Intraoperative Period, Length of Stay, statistics & numerical data, Male, Mental Disorders, etiology, Middle Aged, Prospective Studies, Risk Factors, Thoracic Surgical Procedures, adverse effects, Treatment Outcome, Young Adult |
| Systemic infection and delirium: when cytokines and acetylcholine collide. | van Gool WA, van de Beek D, Eikelenboom P | Lancet | 2010 |
Acetylcholine, physiology, Aged, Cholinergic Agents, pharmacology, Cholinergic Antagonists, adverse effects, Cytokines, physiology, Delirium, chemically induced, Humans, Inflammation, complications, Microglia, drug effects, Middle Aged, Reaction Time, drug effects, Risk Factors, Sepsis, drug therapy, Space Perception, drug effects, Thinking, drug effects |
| The neuroinflammatory hypothesis of delirium. | Cerejeira J, Firmino H, Vaz-Serra A, Mukaetova-Ladinska EB | Acta neuropathologica | 2010 |
Animals, Delirium, immunology, Encephalitis, physiopathology, Humans, Models, Immunological, Models, Neurological |
| Acute behavioural change in a young woman evolving towards cerebellar syndrome. | Naeije G, de Hemptinne Q, Depondt C, Pandolfo M, Legros B | Clinical neurology and neurosurgery | 2010 |
Adult, Autoantibodies, immunology, Autoimmune Diseases, immunology, Behavior, Brain Chemistry, physiology, Coma, etiology, Delirium, etiology, Female, Humans, Magnetic Resonance Imaging, Ovarian Neoplasms, complications, Paraneoplastic Cerebellar Degeneration, etiology, Positron-Emission Tomography, Psychomotor Agitation, psychology, Receptors, N-Methyl-D-Aspartate, immunology, Teratoma, complications |
| Effectiveness of melatonin treatment on circadian rhythm disturbances in dementia. Are there implications for delirium? A systematic review. | de Jonghe A, Korevaar JC, van Munster BC, de Rooij SE | International journal of geriatric psychiatry | 2010 |
Aged, Aged, 80 and over, Central Nervous System Depressants, therapeutic use, Circadian Rhythm, drug effects, Delirium, complications, Dementia, complications, Female, Humans, Male, Melatonin, therapeutic use, Psychiatric Status Rating Scales, Psychomotor Agitation, drug therapy, Sleep, drug effects, Sleep Disorders, Circadian Rhythm, drug therapy |
| Capturing side-effect of medication to identify persons at risk of delirium. | Lauretani F, Ceda GP, Maggio M, Nardelli A, Saccavini M, Ferrucci L | Aging clinical and experimental research | 2010 |
Acetylcholine, deficiency, Aged, Aged, 80 and over, Cholinergic Antagonists, adverse effects, Delirium, etiology, Female, Humans, Male, Risk |
| Different assessment tools for intensive care unit delirium: which score to use? | Luetz A, Heymann A, Radtke FM, Chenitir C, Neuhaus U, Nachtigall I, von Dossow V, Marz S, Eggers V, Heinz A, Wernecke KD, Spies CD | Critical care medicine | 2010 |
Aged, Delirium, diagnosis, Female, Humans, Intensive Care Units, Male, Middle Aged, Observer Variation, Postoperative Complications, diagnosis, Prospective Studies, Psychiatric Status Rating Scales, standards, Reproducibility of Results, Treatment Outcome |
| Delirium in hospitalized elderly patients and post-discharge mortality. | Lima DP, Ochiai ME, Lima AB, Curiati JA, Farfel JM, Filho WJ | Clinics (São Paulo, Brazil) | 2010 |
Age Factors, Aged, Aged, 80 and over, Confounding Factors (Epidemiology), Delirium, blood, Epidemiologic Methods, Female, Hospitalization, Humans, Male, Middle Aged, Mobility Limitation, Patient Discharge, Serum Albumin, analysis |
| Risk factors and incidence of postoperative delirium in elderly patients after elective and emergency surgery. | Ansaloni L, Catena F, Chattat R, Fortuna D, Franceschi C, Mascitti P, Melotti RM | The British journal of surgery | 2010 |
Aged, Aged, 80 and over, Case-Control Studies, Delirium, etiology, Emergency Treatment, psychology, Female, Hospital Mortality, Humans, Length of Stay, Male, Postoperative Complications, psychology, Risk Factors, Surgical Procedures, Elective, psychology |
| Delirium after spinal surgery in Korean population. | Lee JK, Park YS | Spine | 2010 |
Aged, Delirium, epidemiology, Female, Humans, Male, Neurosurgical Procedures, adverse effects, Postoperative Complications, epidemiology, Republic of Korea, Retrospective Studies, Spinal Diseases, epidemiology |
| Sedation and analgesia in critically ill neurologic patients. | Makii JM, Mirski MA, Lewin JJ | Journal of pharmacy practice | 2010 |
Analgesia, methods, Analgesics, Opioid, therapeutic use, Animals, Anti-Anxiety Agents, therapeutic use, Conscious Sedation, methods, Critical Illness, psychology, Humans, Hypnotics and Sedatives, therapeutic use, Nervous System Diseases, complications, Pain, complications, Pain Management |
| Delirium epidemiology in critical care (DECCA): an international study. | Salluh JI, Soares M, Teles JM, Ceraso D, Raimondi N, Nava VS, Blasquez P, Ugarte S, Ibanez-Guzman C, Centeno JV, Laca M, Grecco G, Jimenez E, Árias-Rivera S, Duenas C, Rocha MG, | Critical care (London, England) | 2010 |
Aged, Critical Care, trends, Delirium, diagnosis, Female, Humans, Intensive Care Units, trends, Internationality, Length of Stay, trends, Male, Middle Aged, North America, epidemiology, Risk Factors, South America, epidemiology, Spain, epidemiology |
| High serum cortisol level is associated with increased risk of delirium after coronary artery bypass graft surgery: a prospective cohort study. | Mu DL, Wang DX, Li LH, Shan GJ, Li J, Yu QJ, Shi CX | Critical care (London, England) | 2010 |
Aged, Biological Markers, blood, Cohort Studies, Coronary Artery Bypass, adverse effects, Delirium, blood, Female, Humans, Hydrocortisone, blood, Male, Middle Aged, Postoperative Complications, blood, Prospective Studies, Risk Factors, Treatment Outcome |
| Delirium is not associated with mortality in elderly hip fracture patients. | Juliebø V, Krogseth M, Skovlund E, Engedal K, Ranhoff AH, Wyller TB | Dementia and geriatric cognitive disorders | 2010 |
Accidental Falls, Aged, Aged, 80 and over, Comorbidity, Coronary Disease, epidemiology, Delirium, epidemiology, Dementia, complications, Female, Hip Fractures, complications, Humans, Infection, epidemiology, Institutionalization, Intelligence Tests, Male, Neoplasms, epidemiology, Norway, Prospective Studies, Pulmonary Disease, Chronic Obstructive, epidemiology, Risk Factors, Severity of Illness Index, Stroke, epidemiology |
| Modifiable and nonmodifiable risk factors for postoperative delirium after cardiac surgery with cardiopulmonary bypass. | Burkhart CS, Dell-Kuster S, Gamberini M, Moeckli A, Grapow M, Filipovic M, Seeberger MD, Monsch AU, Strebel SP, Steiner LA | Journal of cardiothoracic and vascular anesthesia | 2010 |
Aged, Aged, 80 and over, Cardiac Surgical Procedures, adverse effects, Cardiopulmonary Bypass, adverse effects, Delirium, chemically induced, Female, Fentanyl, adverse effects, Humans, Male, Postoperative Complications, chemically induced, Prospective Studies, Respiration, Artificial, adverse effects, Risk Factors, Time Factors |
| Preoperative dispositional optimism correlates with a reduced incidence of postoperative delirium and recovery of postoperative cognitive function in cardiac surgical patients. | Hudetz JA, Hoffmann RG, Patterson KM, Byrne AJ, Iqbal Z, Gandhi SD, Warltier DC, Pagel PS | Journal of cardiothoracic and vascular anesthesia | 2010 |
Affect, physiology, Aged, Aged, 80 and over, Attitude to Health, Cardiac Surgical Procedures, adverse effects, Cognition, physiology, Cognition Disorders, epidemiology, Delirium, epidemiology, Female, Humans, Incidence, Male, Middle Aged, Postoperative Complications, epidemiology, Preoperative Period, Recovery of Function, physiology, Time Factors |
| Refeeding syndrome as an iatrogenic cause of delirium: a retrospective pilot study. | Caplan JP, Chang G | Psychosomatics | 2010 |
APACHE, Aged, Chi-Square Distribution, Delirium, etiology, Female, Humans, Iatrogenic Disease, Magnesium, blood, Male, Middle Aged, Phosphates, blood, Pilot Projects, Refeeding Syndrome, complications, Retrospective Studies, Statistics, Nonparametric, Water-Electrolyte Imbalance, complications |
| Delirium scales: A review of current evidence. | Adamis D, Sharma N, Whelan PJ, Macdonald AJ | Aging & mental health | 2010 |
Aged, Aged, 80 and over, Delirium, diagnosis, Evidence-Based Medicine, Humans, Middle Aged, Neuropsychological Tests, standards, Psychiatric Status Rating Scales, Psychometrics, instrumentation |
| Hospital protocols for the inpatient care of older adults: results from a statewide survey. | Neuman MD, Speck RM, Karlawish JH, Schwartz JS, Shea JA | Journal of the American Geriatrics Society | 2010 |
Aged, Geriatric Assessment, methods, Hip Fractures, epidemiology, Hospital Records, statistics & numerical data, Hospitals, General, statistics & numerical data, Humans, Inpatients, statistics & numerical data, Outcome Assessment (Health Care), methods, Pennsylvania, epidemiology, Practice Guidelines as Topic, Prevalence, Questionnaires, Retrospective Studies |
| Early physical medicine and rehabilitation for patients with acute respiratory failure: a quality improvement project. | Needham DM, Korupolu R, Zanni JM, Pradhan P, Colantuoni E, Palmer JB, Brower RG, Fan E | Archives of physical medicine and rehabilitation | 2010 |
Academic Medical Centers, Adult, Aged, Benzodiazepines, administration & dosage, Deep Sedation, utilization, Delirium, chemically induced, Drug Utilization, Female, Humans, Intensive Care Units, organization & administration, Length of Stay, Male, Middle Aged, Occupational Therapy, organization & administration, Patient Care Team, organization & administration, Personnel Staffing and Scheduling, Physical Therapy Modalities, Practice Guidelines as Topic, Prospective Studies, Quality of Health Care, organization & administration, Respiration, Artificial, methods, Respiratory Distress Syndrome, Adult, rehabilitation |
| Administration of olanzapine to prevent postoperative delirium in elderly joint-replacement patients: a randomized, controlled trial. | Larsen KA, Kelly SE, Stern TA, Bode RH, Price LL, Hunter DJ, Gulczynski D, Bierbaum BE, Sweeney GA, Hoikala KA, Cotter JJ, Potter AW | Psychosomatics | 2010 |
Aged, Antipsychotic Agents, therapeutic use, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee, Benzodiazepines, therapeutic use, Chi-Square Distribution, Delirium, etiology, Double-Blind Method, Female, Humans, Male, Placebos, Postoperative Complications, etiology, Psychiatric Status Rating Scales, Statistics, Nonparametric, Treatment Outcome |
| A randomized controlled trial of quetiapine versus placebo in the treatment of delirium. | Tahir TA, Eeles E, Karapareddy V, Muthuvelu P, Chapple S, Phillips B, Adyemo T, Farewell D, Bisson JI | Journal of psychosomatic research | 2010 |
Administration, Oral, Aged, Aged, 80 and over, Antipsychotic Agents, administration & dosage, Brief Psychiatric Rating Scale, Delirium, drug therapy, Diagnostic and Statistical Manual of Mental Disorders, Dibenzothiazepines, administration & dosage, Double-Blind Method, Female, Humans, Male, Middle Aged, Severity of Illness Index, Treatment Outcome |
| Using PDAs to detect cognitive change in the hospitalized elderly patient. | Zalon ML, Sandhaus S, Valenti D, Arzamasova U | Applied nursing research : ANR | 2010 |
Aged, Aged, 80 and over, Clinical Nursing Research, Cognition Disorders, diagnosis, Computers, Handheld, Delirium, diagnosis, Depression, diagnosis, Female, Geriatric Nursing, methods, Hospitalization, Humans, Male, Mental Status Schedule |
| Early postoperative delirium after open-heart cardiac surgery is associated with decreased bispectral EEG and increased cortisol and interleukin-6. | Plaschke K, Fichtenkamm P, Schramm C, Hauth S, Martin E, Verch M, Karck M, Kopitz J | Intensive care medicine | 2010 |
Aged, Cardiac Surgical Procedures, adverse effects, Consciousness Monitors, Delirium, blood, Female, Humans, Hydrocortisone, blood, Interleukin-6, blood, Male, Time Factors |
| Prevalence and associated factors for delirium in critically ill patients at a Japanese intensive care unit. | Tsuruta R, Nakahara T, Miyauchi T, Kutsuna S, Ogino Y, Yamamoto T, Kaneko T, Kawamura Y, Kasaoka S, Maekawa T | General hospital psychiatry | 2010 |
APACHE, Aged, Aged, 80 and over, C-Reactive Protein, metabolism, Critical Illness, epidemiology, Cross-Sectional Studies, Delirium, blood, Female, Humans, Intensive Care Units, statistics & numerical data, Japan, Length of Stay, statistics & numerical data, Male, Mental Status Schedule, Middle Aged, Multivariate Analysis, Respiration, Artificial, psychology, Risk Factors |
| Case report: delirium due to a diltiazem-fentanyl CYP3A4 drug interaction. | Levin TT, Bakr MH, Nikolova T | General hospital psychiatry | 2010 |
Administration, Cutaneous, Aged, 80 and over, Analgesics, Opioid, adverse effects, Calcium Channel Blockers, adverse effects, Cytochrome P-450 CYP3A, antagonists & inhibitors, Delirium, blood, Diltiazem, adverse effects, Drug Interactions, Drug Therapy, Combination, Fentanyl, adverse effects, Humans, Male, Oxycodone, adverse effects, Pain, drug therapy, Tachycardia, Supraventricular, blood |
| Delirium in acute stroke--prevalence and risk factors. | Dahl MH, Rønning OM, Thommessen B | Acta neurologica Scandinavica. Supplementum | 2010 |
Acute Disease, Aged, Aged, 80 and over, Cohort Studies, Comorbidity, trends, Delirium, complications, Female, Humans, Male, Norway, epidemiology, Prevalence, Prospective Studies, Risk Factors, Stroke, complications |
| Risk factors for postoperative delirium in elderly patients with colorectal cancer. | Tei M, Ikeda M, Haraguchi N, Takemasa I, Mizushima T, Ishii H, Yamamoto H, Sekimoto M, Doki Y, Mori M | Surgical endoscopy | 2010 |
Aged, Aged, 80 and over, Colectomy, methods, Colorectal Neoplasms, surgery, Delirium, epidemiology, Female, Humans, Laparoscopy, Logistic Models, Male, Nutritional Status, Postoperative Complications, epidemiology, Retrospective Studies, Risk Factors, Severity of Illness Index, Statistics, Nonparametric |
| Acute pain management in hospitalized patients with cognitive impairment: a study of provider practices and treatment outcomes. | Mehta SS, Siegler EL, Henderson CR, Reid MC | Pain medicine (Malden, Mass.) | 2010 |
Aged, Aged, 80 and over, Analgesics, administration & dosage, Analgesics, Opioid, administration & dosage, Cognition Disorders, complications, Data Interpretation, Statistical, Delirium, chemically induced, Dose-Response Relationship, Drug, Female, Fractures, Bone, complications, Health Personnel, Hospitalization, Humans, Male, Pain, complications, Pain Management, Pain Measurement, methods, Physicians, Retrospective Studies, Treatment Failure, Treatment Outcome |
| A comparison of neuropsychiatric and cognitive profiles in delirium, dementia, comorbid delirium-dementia and cognitively intact controls. | Meagher DJ, Leonard M, Donnelly S, Conroy M, Saunders J, Trzepacz PT | Journal of neurology, neurosurgery, and psychiatry | 2010 | |
| The use of DSM-IV and ICD-10 criteria and diagnostic scales for delirium among cardiac surgery patients: results from the IPDACS study. | Kazmierski J, Kowman M, Banach M, Fendler W, Okonski P, Banys A, Jaszewski R, Rysz J, Sobow T, Kloszewska I | The Journal of neuropsychiatry and clinical neurosciences | 2010 |
Adult, Aged, Aged, 80 and over, Delirium, classification, Diagnostic and Statistical Manual of Mental Disorders, Female, Heart Diseases, surgery, Humans, International Classification of Diseases, standards, Male, Middle Aged, Postoperative Complications, Predictive Value of Tests, ROC Curve, Retrospective Studies, Thoracic Surgery, methods |
| A comparison of three scores to screen for delirium on the surgical ward. | Radtke FM, Franck M, Schust S, Boehme L, Pascher A, Bail HJ, Seeling M, Luetz A, Wernecke KD, Heinz A, Spies CD | World journal of surgery | 2010 |
Aged, Delirium, diagnosis, Diagnostic and Statistical Manual of Mental Disorders, Female, Humans, Male, Mass Screening, Middle Aged, Observer Variation, Postoperative Complications, diagnosis, Sensitivity and Specificity |
| The impact of delirium on the prediction of in-hospital mortality in intensive care patients. | van den Boogaard M, Peters SA, van der Hoeven JG, Dagnelie PC, Leffers P, Pickkers P, Schoonhoven L | Critical care (London, England) | 2010 |
APACHE, Aged, Confidence Intervals, Delirium, diagnosis, Female, Hospital Mortality, Humans, Intensive Care Units, statistics & numerical data, Logistic Models, Male, Middle Aged, Odds Ratio, Prospective Studies, ROC Curve |
| Hospital administrative database underestimates delirium rate after cardiac surgery. | Katznelson R, Djaiani G, Tait G, Wasowicz M, Sutherland AM, Styra R, Lee C, Beattie WS | Canadian journal of anaesthesia = Journal canadien d'anesthésie | 2010 |
Aged, Cardiac Surgical Procedures, adverse effects, Databases, Factual, standards, Delirium, diagnosis, Female, Hospitals, statistics & numerical data, Humans, International Classification of Diseases, Male, Middle Aged, Postoperative Complications, diagnosis, Prospective Studies, Retrospective Studies, Time Factors |
| No shortcuts for delirium prevention. | Inouye SK, Rubin FH, Wierman HR, Supiano MA, Fenlon K | Journal of the American Geriatrics Society | 2010 |
Aged, Delirium, prevention & control, Health Services for the Aged, Humans, Inpatients |
| Depression, anxiety disorders and Type D personality as risk factors for delirium after cardiac surgery. | Tully PJ, Baker RA, Winefield HR, Turnbull DA | The Australian and New Zealand journal of psychiatry | 2010 |
Aged, Anxiety Disorders, complications, Cardiac Surgical Procedures, adverse effects, Confidence Intervals, Delirium, etiology, Depressive Disorder, complications, Depressive Disorder, Major, complications, Female, Heart Valve Prosthesis Implantation, adverse effects, Humans, Male, Middle Aged, Myocardial Revascularization, adverse effects, Odds Ratio, Panic Disorder, complications, Personality, Personality Inventory, Psychiatric Status Rating Scales, Psychotropic Drugs, adverse effects, Risk Factors |
| Effect of rivastigmine as an adjunct to usual care with haloperidol on duration of delirium and mortality in critically ill patients: a multicentre, double-blind, placebo-controlled randomised trial. | van Eijk MM, Roes KC, Honing ML, Kuiper MA, Karakus A, van der Jagt M, Spronk PE, van Gool WA, van der Mast RC, Kesecioglu J, Slooter AJ | Lancet | 2010 |
Aged, Aged, 80 and over, Antipsychotic Agents, therapeutic use, Cholinesterase Inhibitors, administration & dosage, Critical Illness, mortality, Delirium, drug therapy, Double-Blind Method, Drug Administration Schedule, Drug Therapy, Combination, Female, Haloperidol, therapeutic use, Humans, Intensive Care, methods, Intensive Care Units, Kaplan-Meier Estimate, Length of Stay, Male, Middle Aged, Phenylcarbamates, administration & dosage, Severity of Illness Index, Time Factors, Treatment Failure |
| Delirium upon admission to Swiss nursing homes: a cross-sectional study. | von Gunten A, Mosimann UP | Swiss medical weekly | 2010 |
Aged, Aged, 80 and over, Delirium, diagnosis, Female, Homes for the Aged, Humans, Male, Middle Aged, Nursing Homes, Patient Admission, Patient Transfer, Prevalence, Referral and Consultation, Risk Factors, Switzerland, epidemiology |
| Subtle deficits of attention after surgery: quantifying indicators of sub syndrome delirium. | Lowery DP, Wesnes K, Brewster N, Ballard C | International journal of geriatric psychiatry | 2010 |
Aged, Aged, 80 and over, Attention, physiology, Cognition Disorders, complications, Cohort Studies, Delirium, diagnosis, Female, Geriatric Assessment, Humans, Male, Neuropsychological Tests, Postoperative Complications, diagnosis, Preoperative Period, Prospective Studies, Reaction Time, physiology, Surgical Procedures, Elective, adverse effects |
| Clinical associations of delirium in hospitalized adult patients and the role of on admission presentation. | Lin RY, Heacock LC, Bhargave GA, Fogel JF | International journal of geriatric psychiatry | 2010 |
Age Factors, Aged, Aged, 80 and over, Cohort Studies, Delirium, diagnosis, Drug-Related Side Effects and Adverse Reactions, complications, Female, Heart Failure, complications, Humans, Lower Extremity, surgery, Male, Multivariate Analysis, New York, epidemiology, Orthopedics, statistics & numerical data, Patient Admission, statistics & numerical data, Retrospective Studies, Urologic Diseases, complications |
| How can delirium best be prevented and managed in older patients in hospital? | Holroyd-Leduc JM, Khandwala F, Sink KM | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne | 2010 |
Aged, Antipsychotic Agents, therapeutic use, Cholinesterase Inhibitors, therapeutic use, Delirium, diagnosis, Hospitalization, Humans, Hypnotics and Sedatives, therapeutic use, Patient Care Team, Practice Guidelines as Topic, Psychiatric Status Rating Scales, Risk Factors |
| Relationship between cognitive status at admission and incident delirium in older medical inpatients. | Franco JG, Valencia C, Bernal C, Ocampo MV, Trzepacz PT, Pablo Jd, Mejía MA | The Journal of neuropsychiatry and clinical neurosciences | 2010 |
Age Factors, Aged, Aged, 80 and over, Case-Control Studies, Cognition Disorders, complications, Delirium, diagnosis, Female, Geriatric Assessment, Humans, Inpatients, psychology, Male, Middle Aged, Patient Admission, Patient Selection, Psychiatric Status Rating Scales, Risk Factors, Severity of Illness Index, Statistics, Nonparametric |
| Persistent cognitive decline in older hospitalized patients in Taiwan. | Chen CC, Chang YC, Huang GH, Peng JH, Tseng CN | Journal of advanced nursing | 2010 |
Aged, Aged, 80 and over, Attitude to Health, Cognition Disorders, epidemiology, Comorbidity, Convalescence, Epidemiologic Methods, Female, Hospitalization, statistics & numerical data, Humans, Intelligence Tests, statistics & numerical data, Male, Patient Discharge, standards, Prognosis, Taiwan, epidemiology |
| An ACE unit with a delirium room may improve function and equalize length of stay among older delirious medical inpatients. | Flaherty JH, Steele DK, Chibnall JT, Vasudevan VN, Bassil N, Vegi S | The journals of gerontology. Series A, Biological sciences and medical sciences | 2010 |
Activities of Daily Living, Aged, Aged, 80 and over, Delirium, epidemiology, Female, Geriatrics, methods, Humans, Incidence, Inpatients, Length of Stay, Male, Multivariate Analysis, Patient Care Team, Prevalence, Retrospective Studies, Treatment Outcome |
| Hospital use, institutionalisation and mortality associated with delirium. | Eeles EM, Hubbard RE, White SV, O'Mahony MS, Savva GM, Bayer AJ | Age and ageing | 2010 |
Activities of Daily Living, Aged, Aged, 80 and over, Cognition Disorders, epidemiology, Cohort Studies, Delirium, mortality, Female, Frail Elderly, statistics & numerical data, Geriatric Assessment, statistics & numerical data, Hospitals, utilization, Humans, Length of Stay, statistics & numerical data, Male, Polypharmacy, Prospective Studies, Severity of Illness Index, Wales, epidemiology |
| Sedation depth during spinal anesthesia and the development of postoperative delirium in elderly patients undergoing hip fracture repair. | Sieber FE, Zakriya KJ, Gottschalk A, Blute MR, Lee HB, Rosenberg PB, Mears SC | Mayo Clinic proceedings | 2010 |
Aged, 80 and over, Anesthesia, Spinal, adverse effects, Conscious Sedation, adverse effects, Deep Sedation, adverse effects, Delirium, chemically induced, Double-Blind Method, Female, Hip Fractures, surgery, Humans, Hypnotics and Sedatives, adverse effects, Male, Postoperative Complications, etiology, Propofol, adverse effects, Risk Factors |
| Delirium: an independent predictor of functional decline after cardiac surgery. | Rudolph JL, Inouye SK, Jones RN, Yang FM, Fong TG, Levkoff SE, Marcantonio ER | Journal of the American Geriatrics Society | 2010 |
Academic Medical Centers, Activities of Daily Living, Aged, Cardiac Surgical Procedures, adverse effects, Chi-Square Distribution, Delirium, diagnosis, Female, Geriatric Assessment, Hospitals, Veterans, Humans, Linear Models, Male, Middle Aged, Multivariate Analysis, Predictive Value of Tests, Prospective Studies, Recovery of Function, Risk Assessment, Severity of Illness Index, Statistics, Nonparametric, Time Factors |
| Feasibility of family participation in a delirium prevention program for hospitalized older adults. | Rosenbloom-Brunton DA, Henneman EA, Inouye SK | Journal of gerontological nursing | 2010 |
Aged, Aged, 80 and over, Delirium, prevention & control, Education, Continuing, Family, Feasibility Studies, Female, Hospitalization, Humans, Inpatients, Male, Risk Factors |
| Genetic polymorphisms in the DRD2, DRD3, and SLC6A3 gene in elderly patients with delirium. | van Munster BC, Yazdanpanah M, Tanck MW, de Rooij SE, van de Giessen E, Sijbrands EJ, Zwinderman AH, Korevaar JC | American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics | 2010 |
Aged, Base Sequence, Delirium, genetics, Dopamine Plasma Membrane Transport Proteins, genetics, Female, Genotype, Humans, Male, Polymorphism, Single Nucleotide, Receptors, Dopamine D2, genetics, Receptors, Dopamine D3, genetics, Repetitive Sequences, Nucleic Acid |
| White matter abnormalities as a risk factor for postoperative delirium revealed by diffusion tensor imaging. | Shioiri A, Kurumaji A, Takeuchi T, Matsuda H, Arai H, Nishikawa T | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry | 2010 |
Age Factors, Aged, Anisotropy, Brain, pathology, Delirium, pathology, Diffusion Tensor Imaging, methods, Female, Humans, Male, Middle Aged, Nerve Fibers, Myelinated, pathology, Postoperative Complications, pathology, Predictive Value of Tests, Psychomotor Performance, Risk Factors |
| Delirium in the emergency department: an independent predictor of death within 6 months. | Han JH, Shintani A, Eden S, Morandi A, Solberg LM, Schnelle J, Dittus RS, Storrow AB, Ely EW | Annals of emergency medicine | 2010 |
Aged, Delirium, mortality, Emergency Service, Hospital, statistics & numerical data, Female, Humans, Kaplan-Meier Estimate, Male, Nursing Homes, statistics & numerical data, Prognosis, Proportional Hazards Models, Prospective Studies |
| Delirium incidents in three Danish intensive care units. | Svenningsen H, Tønnesen E | Nursing in critical care | 2011 |
Adult, Age Distribution, Aged, Aged, 80 and over, Analgesics, Opioid, administration & dosage, Delirium, chemically induced, Denmark, epidemiology, Female, Fentanyl, administration & dosage, Follow-Up Studies, Humans, Hypnotics and Sedatives, administration & dosage, Incidence, Intensive Care Units, statistics & numerical data, Male, Middle Aged, Prospective Studies, Risk Factors |
| Preoperative regional cerebral oxygen saturation is a predictor of postoperative delirium in on-pump cardiac surgery patients: a prospective observational trial. | Schoen J, Meyerrose J, Paarmann H, Heringlake M, Hueppe M, Berger KU | Critical care (London, England) | 2011 |
Aged, Cardiac Surgical Procedures, adverse effects, Cerebrum, metabolism, Delirium, etiology, Female, Heart-Assist Devices, Humans, Male, Middle Aged, Oximetry, Oxygen, metabolism, Predictive Value of Tests, Prospective Studies |
| Cognitive effects of atypical antipsychotic medications in patients with Alzheimer's disease: outcomes from CATIE-AD. | Vigen CL, Mack WJ, Keefe RS, Sano M, Sultzer DL, Stroup TS, Dagerman KS, Hsiao JK, Lebowitz BD, Lyketsos CG, Tariot PN, Zheng L, Schneider LS | The American journal of psychiatry | 2011 |
Activities of Daily Living, classification, Aged, Aged, 80 and over, Alzheimer Disease, diagnosis, Antipsychotic Agents, adverse effects, Benzodiazepines, adverse effects, Cognition Disorders, chemically induced, Dibenzothiazepines, adverse effects, Disease Progression, Double-Blind Method, Drug Substitution, Female, Follow-Up Studies, Humans, Male, Mental Status Schedule, statistics & numerical data, Neuropsychological Tests, statistics & numerical data, Patient Dropouts, statistics & numerical data, Risperidone, adverse effects |
| Melatonin decreases delirium in elderly patients: a randomized, placebo-controlled trial. | Al-Aama T, Brymer C, Gutmanis I, Woolmore-Goodwin SM, Esbaugh J, Dasgupta M | International journal of geriatric psychiatry | 2011 |
Acute Disease, Aged, Aged, 80 and over, Central Nervous System Depressants, administration & dosage, Delirium, prevention & control, Double-Blind Method, Female, Humans, Male, Melatonin, administration & dosage, Ontario |
| Delirium in older emergency department patients is an independent predictor of hospital length of stay. | Han JH, Eden S, Shintani A, Morandi A, Schnelle J, Dittus RS, Storrow AB, Ely EW | Academic emergency medicine : official journal of the Society for Academic Emergency Medicine | 2011 |
Academic Medical Centers, Aged, Aged, 80 and over, Delirium, diagnosis, Emergency Service, Hospital, Female, Geriatric Assessment, Hospitalization, statistics & numerical data, Humans, Length of Stay, statistics & numerical data, Male, Prognosis, Proportional Hazards Models, Prospective Studies |
| Postoperative delirium. Part 1: pathophysiology and risk factors. | Steiner LA | European journal of anaesthesiology | 2011 |
Age Factors, Animals, Apoptosis, Brain, physiopathology, Delirium, etiology, Humans, Inflammation, etiology, Neurotransmitter Agents, metabolism, Postoperative Complications, etiology, Risk Factors |
| Postoperative delirium. part 2: detection, prevention and treatment. | Steiner LA | European journal of anaesthesiology | 2011 |
Aged, Anesthesia, methods, Antipsychotic Agents, therapeutic use, Benzodiazepines, therapeutic use, Cholinesterase Inhibitors, therapeutic use, Clinical Trials as Topic, Confusion, Delirium, diagnosis, Dexmedetomidine, therapeutic use, Humans, Intensive Care, methods, Intensive Care Units, Postoperative Complications, Risk, Sensitivity and Specificity |
| Treatment characteristics of delirium superimposed on dementia. | Boettger S, Passik S, Breitbart W | International psychogeriatrics / IPA | 2011 |
Aged, Aged, 80 and over, Aging, psychology, Comorbidity, Delirium, diagnosis, Dementia, diagnosis, Diagnosis, Differential, Female, Humans, Male, Middle Aged, Prognosis, Psychiatric Status Rating Scales, standards, Risk Factors, Sampling Studies |
| Evaluating the effectiveness of educational interventions to prevent delirium. | Wand AP | Australasian journal on ageing | 2011 |
Clinical Competence, Delirium, prevention & control, Geriatrics, methods, Humans, Patient Education as Topic, organization & administration |
| Delirium superimposed on dementia: defining disease states and course from longitudinal measurements of a multivariate index using latent class analysis and hidden Markov chains. | Ciampi A, Dyachenko A, Cole M, McCusker J | International psychogeriatrics / IPA | 2011 |
Aged, Aged, 80 and over, Comorbidity, Delirium, diagnosis, Dementia, diagnosis, Diagnosis, Differential, Female, Humans, Male, Multivariate Analysis, Psychiatric Status Rating Scales, standards, Severity of Illness Index |
| Delirium: a strategic plan to bring an ancient disease into the 21st century. | Rudolph JL, Boustani M, Kamholz B, Shaughnessey M, Shay K, | Journal of the American Geriatrics Society | 2011 |
Aged, Delirium, therapy, Goals, Humans |
| Procalcitonin and C-reactive protein levels at admission as predictors of duration of acute brain dysfunction in critically ill patients. | McGrane S, Girard TD, Thompson JL, Shintani AK, Woodworth A, Ely EW, Pandharipande PP | Critical care (London, England) | 2011 |
Aged, Biological Markers, blood, C-Reactive Protein, analysis, Calcitonin, blood, Critical Illness, Delirium, blood, Female, Humans, Male, Middle Aged, Patient Admission, Pilot Projects, Predictive Value of Tests, Prospective Studies, Protein Precursors, blood, Respiration, Artificial, Time Factors |
| Changes in symptoms and inpatient mortality: a study in advanced cancer patients admitted to an acute palliative care unit in a comprehensive cancer center. | Mori M, Parsons HA, De la Cruz M, Elsayem A, Palla SL, Liu J, Li Z, Palmer L, Bruera E, Fadul NA | Journal of palliative medicine | 2011 |
Aged, Cancer Care Facilities, Female, Humans, Inpatients, Male, Medical Audit, Middle Aged, Neoplasms, mortality, Outcome Assessment (Health Care), Palliative Care, Retrospective Studies |
| Identification and management of in-hospital drug-induced delirium in older patients. | Catic AG | Drugs & aging | 2011 |
Aged, Analgesics, adverse effects, Antidepressive Agents, adverse effects, Benzodiazepines, adverse effects, Cholinergic Antagonists, adverse effects, Delirium, chemically induced, Hospitals, statistics & numerical data, Humans |
| Predisposing factors for postoperative delirium after hip fracture repair in individuals with and without dementia. | Lee HB, Mears SC, Rosenberg PB, Leoutsakos JM, Gottschalk A, Sieber FE | Journal of the American Geriatrics Society | 2011 |
Aged, Aged, 80 and over, Causality, Delirium, epidemiology, Dementia, complications, Female, Hip Fractures, surgery, Humans, Male, Postoperative Complications, epidemiology, Prospective Studies, Risk Factors |