Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Effects of remimazolam and propofol on sleep rhythm and delirium after spinal surgery in elderly patients
Authors
Yaqiu, L. Heng, Z. Ruimin, W. Xuri, W.
Year
2025
Journal
Perioper Med (Lond)
Abstract

OBJECTIVE: This study aims to investigate the effects of remimazolam on postoperative melatonin secretion, sleep rhythm, and postoperative delirium (POD) in elderly patients undergoing spinal surgery. METHODS: We selected 120 elderly patients scheduled for elective spinal surgery (lumbar interbody fusion via a posterior approach) under general anaesthesia from November 2023 to January 2024. They were divided into 2 groups according to medication, the remimazolam group (R group) and the propofol group (P group), with 60 patients in each group. The R group received an induction dose of remimazolam 0.2 ~ 0.3 mg/kg, followed by a continuous infusion of remimazolam at 0.1-0.2 mg/kg/h for maintenance. The P group received an induction dose of propofol 1.5 ~ 2.0 mg/kg, followed by a continuous infusion of propofol at 4-6 mg/kg/h for maintenance. Melatonin and cortisol concentrations were measured at 04:00 on the day of surgery and postoperative days 1, 2, and 3. The Pittsburgh Sleep Quality Index (PSQI) and resting visual analog scale (VAS) pain scores were recorded on the day before surgery, and on postoperative days 1 and 2, as well as prior to discharge. Additionally, we documented extubation time, PACU stay duration, total and effective button presses on the analgesia pump, instances of supplemental analgesia, and occurrence of complications. RESULTS: Compared to the P group, the R group exhibited significantly shorter extubation time and PACU stay duration (P < 0.05). On postoperative days 1 and 2 at 04:00, melatonin concentrations were significantly higher, cortisol concentrations were significantly lower, and PSQI scores were significantly reduced in the R group (P < 0.05). The incidence of POD and postoperative sleep disturbance (POSD) was also significantly lower in the R group (P < 0.05). Furthermore, on postoperative day 1, the PSQI and resting VAS pain scores in the R group were significantly lower compared to the P group (P < 0.05). There were no statistically significant differences between the two groups in terms of surgery duration, anaesthesia duration, total and effective analgesia pump button presses, supplemental analgesia rates, intraoperative hypotension, or incidences of postoperative nausea, vomiting, dizziness, and respiratory depression (P > 0.05). CONCLUSION: The use of remimazolam in elderly patients undergoing spinal surgery has a minimal impact on postoperative melatonin and cortisol secretion rhythms and sleep patterns, and may reduce the incidence of POD and alleviate postoperative sleep disturbances.

PMID

PMID: 39934906

PMCID: PMC11817572

Keywords

Cortisol Melatonin Postoperative delirium Remimazolam Sleep rhythm Spinal surgery

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Total Records Found: 6665, showing 100 per page
TitleAuthorsJournalYearKeywords
Priority areas for outcomes improvement among older adults undergoing inpatient general surgery inclusive of geriatric-pertinent complications Kazaure, H. S. Johnson, K. S. Rosenthal, R. Lagoo-Deenadayalan, S. World J Surg 2024

Humans
Aged
Female
Male
*Postoperative Complications/epidemiology
Aged, 80 and over
*Surgical Procedures, Operative/adverse effects
Pressure Ulcer/surgery
Delirium/epidemiology/etiology
Quality Improvement
Geriatric Assessment
Retrospective Studies
General Surgery
Nsqip
delirium
geriatrics
outcomes
quality
surgery

Short-Term Outcome of Patients in Delirium at Medical Intensive Care Unit Khatri, R. Dhungana, S. Ojha, S. P. Khatri, S. Khadka, S. K, C. P. J Nepal Health Res Counc 2024

Humans
*Delirium/epidemiology/diagnosis
Male
Female
*Intensive Care Units/statistics & numerical data
Cross-Sectional Studies
Nepal/epidemiology
Middle Aged
*Length of Stay/statistics & numerical data
Adult
Aged
Prevalence
Critical Illness
Delirium
length of ICU stay
mortality pattern

Erythropoietin for the prevention of postoperative neurocognitive disorder in older adult patients undergoing total joint arthroplasty: a randomized controlled study Kim, E. J. Park, K. K. Choi, S. Y. Ju, H. M. Kim, T. L. Kim, J. Kim, S. Y. Koo, B. N. BMC Anesthesiol 2024

Humans
Male
Female
Aged
*Erythropoietin/therapeutic use/administration & dosage
Double-Blind Method
Postoperative Cognitive Complications/prevention & control/epidemiology
Postoperative Complications/prevention & control
Delirium/prevention & control/epidemiology
Neurocognitive Disorders/prevention & control/etiology
Erythropoietin
Postoperative delirium
Postoperative neurocognition

Multilevel factors influencing falls of older patients in hospital: The risk of hospital-induced delirium and the impact of nurse staffing Kim, J. Lee, E. Lee, S. Geriatr Nurs 2024

Delirium
Falls
Nurse staffing
Older patients

Preoperative cognitive training for the prevention of postoperative delirium and cognitive dysfunction: a systematic review and meta-analysis Lau, K. T. Chiu, L. C. S. Fong, J. S. Y. Chan, A. K. M. Ho, K. M. Lee, A. Perioper Med (Lond) 2024

Cognitive dysfunction
Cognitive rehabilitation
Confusion
Delayed neurocognitive recovery
Delirium
Neurocognitive disorders
Neuropsychological tests
Postoperative cognitive complications
Preoperative care

Reinforcement learning model for optimizing dexmedetomidine dosing to prevent delirium in critically ill patients Lee, H. Y. Chung, S. Hyeon, D. Yang, H. L. Lee, H. C. Ryu, H. G. Lee, H. NPJ Digit Med 2024

Delirium

ICU

Dexmedetomidine

Artificial Intelligence model for Delirium prevention

World delirium awareness and quality survey in 2023-a worldwide point prevalence study Lindroth, H. Liu, K. Szalacha, L. Ashkenazy, S. Bellelli, G. van den Boogaard, M. Caplan, G. Chung, C. R. Elhadi, M. Gurjar, M. Heras-La-Calle, G. Hoffman, M. Jeitziner, M. M. Krewulak, K. Mailhot, T. Morandi, A. Nawa, R. K. Oh, E. S. Collet, M. O. Paulin Age Ageing 2024

Humans
*Delirium/epidemiology/diagnosis
Prevalence
Cross-Sectional Studies
Prospective Studies
Global Health
Health Knowledge, Attitudes, Practice
Adult
Male
Female
Health Care Surveys
Aged
Surveys and Questionnaires
delivery of health care
global delirium prevalence
older people
standard of practice

Effects of melatonin on the prevention of delirium in hospitalized older patients: systematic review and meta-analysis Liu, L. Ma, X. Song, Z. Li, J. Zhao, Y. Meng, C. Wang, S. Miao, G. Liu, P. BMC Pharmacol Toxicol 2024

*Melatonin/therapeutic use
Humans
*Delirium/prevention & control/drug therapy
Aged
*Hospitalization
*Indenes/therapeutic use
Randomized Controlled Trials as Topic
Length of Stay
Aged, 80 and over
Delirium
Melatonin
Older patients

Pharmacologic prophylaxis of postoperative delirium in elderly patients: A network meta-analysis of randomized controlled trials Liu, T. H. Lin, Y. T. Wu, J. Y. Huang, P. Y. Tsai, W. W. Lai, C. C. Kao, P. H. Su, K. P. J Psychiatr Res 2024

Delirium
Elderly
Pharmacological interventions
Postoperative delirium

Hospitalization and Hospitalized Delirium Are Associated With Decreased Access to Kidney Transplantation and Increased Risk of Waitlist Mortality Long, J. J. Hong, J. Liu, Y. Nalatwad, A. Li, Y. Ghildayal, N. Johnston, E. A. Schwartzberg, J. Ali, N. Oermann, E. Mankowski, M. Gelb, B. E. Chanan, E. L. Chodosh, J. L. Mathur, A. Segev, D. L. McAdams-DeMarco, M. A. Clin Transplant 2024

Humans
*Delirium/etiology/mortality
Male
Female
*Kidney Transplantation/adverse effects
*Hospitalization/statistics & numerical data
*Waiting Lists/mortality
Prospective Studies
Middle Aged
Risk Factors
Prognosis
Follow-Up Studies
Kidney Failure, Chronic/surgery/mortality
Aged
Survival Rate
Adult
Health Services Accessibility
delirium
hospitalization
kidney transplantation
mortality
waitlist

The impact of patient- and family-centered care interventions on intensive care unit outcomes: a meta-analysis of randomized controlled trials Lv, Y. Li, P. Li, R. Zhang, T. Cai, K. Braz J Anesthesiol 2024

Critical care
Delirium
Intensive Care Unit
Meta analysis
Patient centered care

Effect of intraoperative dexmedetomidine on heart-type fatty acid binding protein, CK-MB, and cardiac troponin I levels, and postoperative delirium in patients with heart valve replacement Ma, Z. Liu, Y. Zhang, C. Li, D. Huo, J. Cao, F. Am J Transl Res 2024

Dexmedetomidine
cardiac troponin I
creatine kinase-MB
heart valve replacement
heart-type fatty acid binding protein
postoperative delirium

Experience of carers for older people with delirium: a qualitative study Mahmoud, A. Raghuraman, S. Richards, E. Morgan-Trimmer, S. Goodwin, V. A. Anderson, R. Allan, L. Aging Ment Health 2024

Delirium
carer burnout
carers
frailty
qualitative

Effects of E-Learning Materials on Caregivers' Knowledge about the 3Ds of Geriatric Psychiatry Mamayson, R. F. Cawalo, W. P. Morales, E. J. P. Morla, R. X. D. Nebrida, K. L. M. Orca, Z. M. P. Pacolor, L. S. R. Paran, D. P. Ramos, A. Y. P. Razon, E. N. S. Sales, Mmac Soriano, Sjmg Tagorda, Akdi Tingson, R. D. B. Acta Med Philipp 2024

3Ds
delirium
dementia
depression
e-book-based remote learning
geriatric psychiatry
video-based learning

Knowledge of Delirium Among ICU Nursing Staff: A Cross-sectional Study Mathew, C. Ashok, A. V. Punnoose, V. P. Indian J Psychol Med 2024

Delirium
Icu
delirium knowledge
neurocognitive disorders
nurses

Implementation of Evidence-Based International Recommendations Reduces Postoperative Delirium Rate in Patients Undergoing Cardiac Surgery or Interventions: A System-Based Quality Improvement Study Milz, S. Holaubek, C. Siebel, J. Hulde, N. Wefer, F. Fruend, A. Tigges-Limmer, K. Gummert, J. von Dossow, V. Rev Cardiovasc Med 2024

cardiac surgery
delirium
perioperative care
postoperative care

Inflammatory Indices and Their Associations with Postoperative Delirium Mintz, G. E. Marcantonio, E. R. Walston, J. D. Dillon, S. T. Jung, Y. Trivedi, S. Gu, X. Fong, T. G. Cavallari, M. Touroutoglou, A. Dickerson, B. C. Jones, R. N. Shafi, M. M. Pascual-Leone, A. Travison, T. G. Inouye, S. K. Libermann, T. A. Ngo, L. H. Vasu J Gerontol A Biol Sci Med Sci 2024

Cam
Lasso
pathophysiology
prediction
surgery

Efficacy of a melatonin receptor agonist and orexin receptor antagonists in preventing delirium symptoms in the olderly patients with stroke: a retrospective study Miyoshi, Y. Shigetsura, Y. Hira, D. Maki, T. Kawashima, H. Sugita, N. Sugawara, N. Kitada, N. Hirai, M. Kawata, M. Endo, H. Kojima, Y. Ikuta, K. Katsube, Y. Imayoshi, N. Nakagawa, S. Tsuda, M. Terada, T. J Pharm Health Care Sci 2024

Delirium
Melatonin receptor agonist
Orexin receptor antagonist
Stroke

A Cross-Sectional Survey on Nurses' Utilization of Risk Assessment and Screening for Postoperative Delirium in Older Patients Following Hip Fracture Surgery in Tertiary Hospitals in Jiangsu Province, China Yang, J. Liu, M. Yang, L. Fang, S. Wang, G. Gu, Z. Risk Manag Healthc Policy 2024

delirium
older patients
postoperative Hip fracture
risk assessment and screening

Reliability and Validity of Hindi Version of the Confusion Assessment Method for Intensive Care Unit (CAM-ICU) for Diagnosis of Delirium: A Cohort Study Salhotra, R. Bose, A. Srivastava, S. Mohta, M. Pandarinathan, K. Rautela, R. S. Indian J Crit Care Med 2024

Critical care
Delirium
Diagnosis
Diagnostic and Statistical manual of mental disorders
translation

Classics in Chemical Neuroscience: Deliriant Antihistaminic Drugs Nerush, M. O. Shevyrin, V. A. Golushko, N. I. Moskalenko, A. M. Rosemberg, D. B. De Abreu, M. S. Yang, L. E. Galstyan, D. S. Lim, L. W. Demin, K. A. Kalueff, A. V. ACS Chem Neurosci 2024

Animal models
Anticholinergic activity
Antihistamines
Delirium
Drug use and abuse
First generation H1 antagonists
Histamine
Side effects

Role of Intraoperative Neurophysiological Monitoring in Predicting Postoperative Delirium in Patients Undergoing Carotid Endarterectomy Surgeries Al-Qudah, A. M. Sivaguru, S. Anetakis, K. Crammond, D. Balzer, J. Subramaniam, K. Sadhasivam, S. Shandal, V. Thirumala, P. Eur Neurol 2024

Electroencephalography (EEG)

Somatosensory Evoked Potentials (SSEP)

Intraoperative neurophysiological monitoring (IONM)

Postoperative Delirium

Carotid Endarterectomy (CEA) surgery

Delirium and frailty in older adults: Clinical overlap and biological underpinnings Bellelli, G. Triolo, F. Ferrara, M. C. Deiner, S. G. Morandi, A. Cesari, M. Davis, D. Marengoni, A. Inzitari, M. Watne, L. O. Rockwood, K. Vetrano, D. L. J Intern Med 2024

Humans
*Delirium/physiopathology/etiology/epidemiology
Aged
*Frailty/complications
Risk Factors
*Frail Elderly
Geriatric Assessment
delirium
frailty
hallmarks of aging
review

Adherence to optimal delirium management practices in intensive care units in Brazil: a nationwide survey Bispo, M. M. Souza, Rcds JBI Evid Implement 2024

Delirium

ICU

Delirium prevention

Delirium treatment

Best practices

Adherence

Patient- and family-centered care in adult ICU (FAM-ICU): A protocol for a feasibility study Bohart, S. Waldau, T. Andreasen, A. S. Møller, A. M. Thomsen, T. Acta Anaesthesiol Scand 2024

family
feasibility studies
intensive care units
interdisciplinary research
patient‐centered care

Mortality-related factors in older adults with delirium: A prospective observational study Boran, Y. Altuncı, Y. A. Yalçınlı, S. Geriatr Nurs 2024

Delirium
Emergency department
Mortality
Older adults

A Prospective Observational Cohort Study of Language Preference and Preoperative Cognitive Screening in Older Adults: Do Language Disparities Exist in Cognitive Screening and Does the Association Between Test Results and Postoperative Delirium Differ Base Canales, C. Ramirez, C. M. Yang, S. C. Feinberg, S. A. Grogan, T. R. Whittington, R. A. Sarkisian, C. Cannesson, M. Anesth Analg 2024

Humans
Aged
Female
Male
Prospective Studies
Aged, 80 and over
*Cognition
*Language
Preoperative Care/methods
Delirium/diagnosis/epidemiology/psychology
Cohort Studies
Postoperative Complications/diagnosis/epidemiology/psychology
Risk Factors
Geriatric Assessment/methods
Predictive Value of Tests
Mental Status and Dementia Tests

Machine Learning for Prediction of Postoperative Delirium in Adult Patients: A Systematic Review and Meta-analysis Chen, H. Yu, D. Zhang, J. Li, J. Clin Ther 2024

Artificial intelligence
Machine learning
Meta-analysis
Postoperative delirium

A Novel Nomogram Developed Based on Preoperative Immune Inflammation-Related Indicators for the Prediction of Postoperative Delirium Risk in Elderly Hip Fracture Cases: A Single-Center Retrospective Cohort Study Chen, X. Fan, Y. Tu, H. Chen, J. J Inflamm Res 2024

elderly
hip fracture
immune inflammation related indicators
nomogram
postoperative delirium

Serum Albumin Level at Intensive Care Unit Admission and Delirium Duration and Severity in Critically Ill Adults Chi, R. Perkins, A. J. Khalifeh, Y. Savsani, P. Jawaid, S. Moiz, S. Wang, S. Khan, S. H. Gao, S. Khan, B. A. Am J Crit Care 2024

Humans
*Delirium/blood/diagnosis/epidemiology
Male
Female
*Intensive Care Units
Middle Aged
*Critical Illness
*Serum Albumin/analysis
*Severity of Illness Index
Aged
Time Factors
Hypoalbuminemia/epidemiology
Adult

Association between exposure to proton pump inhibitors and delirium: a descriptive and disproportionality analysis of VigiBase Decros, A. Minoc, E. M. Lelong-Boulouard, V. Chrétien, B. Meurant, A. Alexandre, J. Dolladille, C. Villain, C. BMJ Open 2024

Humans
*Proton Pump Inhibitors/adverse effects
*Delirium/chemically induced/epidemiology
*Hyponatremia/chemically induced/epidemiology
Female
Male
*Pharmacovigilance
Aged
Middle Aged
Adverse Drug Reaction Reporting Systems/statistics & numerical data
Adult
Aged, 80 and over
Adverse events
Clinical pharmacology
Delirium
Delirium & cognitive disorders

Nutrition care for older adults with delirium: A scoping review Deeth, S. Stevens, S. Bell, J. Mudge, A. J Clin Nurs 2024

Humans
*Delirium/nursing
Aged
Malnutrition/prevention & control
Aged, 80 and over
Nutrition Therapy/methods
delirium
geriatric medicine
malnutrition
nutrition and dietetics
older adults

Benefits of an automated postoperative delirium risk prediction tool combined with non-pharmacological delirium prevention on delirium incidence and length of stay: a before-after analysis based on a quality improvement project Dodsworth, B. T. Reeve, K. A. Zozman, M. Meier, P. Buddeberg, F. Möller, M. Wildhaber, S. P. Kedda, M. A. Böttger, S. Stocker, R. Gelsomino, N. S. Age Ageing 2024

Humans
*Length of Stay/statistics & numerical data
Aged
Male
Female
Risk Assessment
*Quality Improvement
Incidence
*Delirium/prevention & control/diagnosis/epidemiology
Risk Factors
Switzerland/epidemiology
Aged, 80 and over
Middle Aged
Postoperative Complications/prevention & control/epidemiology/diagnosis
Time Factors
Predictive Value of Tests
delirium
length of stay
non-pharmacological prevention
older people
postoperative
risk

Mechanisms underlying delirium in patients with critical illness Fan, Y. Y. Luo, R. Y. Wang, M. T. Yuan, C. Y. Sun, Y. Y. Jing, J. Y. Front Aging Neurosci 2024

cognition impairment
critical illness
delirium
mechanism
review

Early processed electroencephalography for the monitoring of deeply sedated mechanically ventilated critically ill patients Favre, E. Bernini, A. Miroz, J. P. Abed-Maillard, S. Ramelet, A. S. Oddo, M. Nurs Crit Care 2024

Humans
*Critical Illness
Male
*Deep Sedation/methods
*Respiration, Artificial
Female
*Electroencephalography/methods
*Intensive Care Units
*Delirium/diagnosis
Monitoring, Physiologic/methods
Middle Aged
Aged
Hypnotics and Sedatives/administration & dosage
critical care
delirium
processed electroencephalogaphy
sedation

Post-operative delirium in different age groups and subtypes: a systematic review of case reports Guo, J. Guo, X. Liu, W. Zhou, A. Han, J. Yi, R. Dong, L. Zhou, Y. Front Neurol 2024

acute confusion
age
post-operative delirium
subtype
systematic review

Delirium diagnostic tools in the postoperative setting: A scoping review protocol Hansen, C. L. Thomsen, T. Tøgern, A. Møller, A. M. Vester-Andersen, M. Overgaard, S. Foss, N. B. Hägi-Pedersen, D. Acta Anaesthesiol Scand 2024

Humans
*Delirium/diagnosis
*Postoperative Complications/diagnosis
delirium
diagnostic assessment
diagnostic instrument
diagnostic test
diagnostic tool
postanesthesia
postoperative
postoperative cognitive complication
postoperative delirium
postsurgical

Assessment of ICU nurses' competency towards delirium among critically ill patients Hebeshy, M. I. Gaballah, S. H. Ibrahim, N. M. BMC Nurs 2024

Attitudes
Delirium
ICU nurses
Knowledge
Patient outcomes
Practice

Role of glia in delirium: proposed mechanisms and translational implications Heffernan Á, B. Steinruecke, M. Dempsey, G. Chandran, S. Selvaraj, B. T. Jiwaji, Z. Stavrou, M. Mol Psychiatry 2024

Delirium

Morbidity and mortality

Pathophysiology

Glial cells

Astrocytes

Blood brain barrier

Using Machine Learning and Electronic Health Records to Identify Neuropsychiatric Risk Scores for Delirium in ICU and General Hospital Settings Heikal, M. Saad, H. Ghanime, P. M. Bou Dargham, T. Bizri, M. Kobeissy, F. El Hajj, W. Talih, F. Neuropsychiatr Dis Treat 2024

Delirium
Hospital-acquired delirium
ICU delirium
clinical indicators
electronic health records
machine learning

A Study of Knowledge and Recognition on Postoperative Delirium Among Postanesthesia Care Unit (PACU) Nurses Hsu, Y. C. Wang, S. Y. Su, S. F. Lin, L. W. J Perianesth Nurs 2024

anesthesia
knowledge
postanesthesia care unit nurses
postoperative delirium
recognition

Comparing Bispectral Index Monitoring vs Clinical Assessment for Deep Sedation in the ICU: Effects on Delirium Reduction and Sedative Drug Doses-A Randomized Trial Huespe, I. Giunta, D. Acosta, K. Avila, D. Prado, E. Sanghavi, D. Bisso, I. C. Giannasi, S. Carini, F. C. Chest 2024

Humans
Male
Female
*Hypnotics and Sedatives/administration & dosage
*Deep Sedation/methods
Middle Aged
*Intensive Care Units
*Delirium/prevention & control/diagnosis
Aged
Consciousness Monitors
Electroencephalography/methods
Propofol/administration & dosage/adverse effects
Dose-Response Relationship, Drug
EEG-based sedation
bispectral index
critically ill patients
deep sedation
delirium

Assessing the Risk of Postoperative Delirium Through Comprehensive Geriatric Assessment and Eastern Cooperative Oncology Group Performance Status of Elderly Patients With Gastric Cancer Itami, T. Yamamoto, K. Kurokawa, Y. Saito, T. Takahashi, T. Momose, K. Yamashita, K. Tanaka, K. Makino, T. Yasunobe, Y. Akasaka, H. Fujimoto, T. Yamamoto, K. Nakajima, K. Eguchi, H. Doki, Y. Ann Surg Oncol 2024

Comprehensive geriatric assessment
Delirium
Eastern Cooperative Oncology Group performance status
Elderly patients
Gastrectomy
Gastric cancer
Mini-Mental State Examination

Efficacy and safety of aripiprazole in the treatment of delirium Jarosz, M. Badura Brzoza, K. A. Psychiatr Pol 2024

Humans
*Antipsychotic Agents/administration & dosage/adverse effects
*Aripiprazole/administration & dosage/adverse effects
*Delirium/drug therapy
Treatment Outcome
aripiprazole
delirium
treatment

The hot spots and global trends of prevention and treatment in postoperative delirium (POD) from 2004 to 2023: A bibliometric analysis Jiang, C. Tian, Z. Jiang, M. Xu, C. Mao, M. Feng, S. Yuan, H. Surg Open Sci 2024

Bibliometric analysis
Hot spots
Postoperative delirium
Prevention
Treatment

Impact of the Charlson Comorbidity Index on Delirium Outcomes Kalyan, P. Parulekar, M. Cureus 2024

charlson comorbidity index
delirium
healthcare outcomes
inpatient
older adults

Postoperative pain and neurocognitive outcomes after noncardiac surgery: a systematic review and dose-response meta-analysis Khaled, M. Sabac, D. Fuda, M. Koubaesh, C. Gallab, J. Qu, M. Lo Bianco, G. Shanthanna, H. Paul, J. Thabane, L. Marcucci, M. Br J Anaesth 2024

delirium
dose–response meta-analysis
noncardiac surgery
postoperative cognitive dysfunction
postoperative pain

Pharmacological Management of Sleep-Wake Disturbances in Delirium Levinsohn, E. A. Radhakrishnan, V. Euting, H. Kaplan, G. B. J Clin Pharmacol 2024

Dora
delirium
dexmedetomidine
insomnia
melatonin
ramelteon

The effect of intraoperative midazolam on postoperative delirium in older surgical patients: a prospective, multicentre cohort study Li, H. Liu, C. Yang, Y. Wu, Q. P. Xu, J. M. Wang, D. F. Sun, J. J. Mao, M. M. Lou, J. S. Liu, Y. H. Cao, J. B. Duan, C. Y. Mi, W. D. Anesthesiology 2024

Midazolam

Benzodiazepine

Postoperative Delirium

Non-cardiac surgery

3D-CAM

Family involvement in preventing delirium in critically ill patients: A systematic review and meta-analysis Li, J. Fan, Y. Luo, R. Wang, Y. Yin, N. Qi, W. Huang, T. Zhang, J. Jing, J. Int J Nurs Stud 2024

Critical illness
Delirium
Family nursing
Meta-analysis
Prevention

Assessing the Risk of Delirium and Death in Sepsis Using the Braden Score: A Retrospective Study Li, X. Tang, Y. Bai, Z. Liang, X. Huang, X. Chen, J. Cheng, H. Lyu, J. Wang, Y. J Clin Nurs 2024

Braden score
delirium
intensive care unit
mortality
sepsis

Nutritional Status and Inflammation as Mediators of Physical Performance and Delirium in Elderly Community-Acquired Pneumonia Patients: A Retrospective Cohort Study Liao, J. Shen, X. Du, Z. Wang, X. Miao, L. Clin Interv Aging 2024

Humans
Male
Female
Retrospective Studies
*Delirium
*Community-Acquired Infections
*C-Reactive Protein/analysis
Aged
*Nutritional Status
Aged, 80 and over
*Pneumonia
*Inflammation
*Physical Functional Performance
Geriatric Assessment
Malnutrition
Hospitalization
Logistic Models
Risk Factors
delirium
inflammation
nutritional status
physical performance

Predicting delirium in older adults with community-acquired pneumonia: A retrospective analysis of stress hyperglycemia ratio and its interactions with nutrition and inflammation Liao, J. Xie, C. Shen, X. Miao, L. Arch Gerontol Geriatr 2024

Community-acquired pneumonia
Delirium
Interleukin-6
Nutritional status
Stress hyperglycemia

A Comprehensive Intervention Program for Postoperative Delirium Prevention in Elderly Patients Undergoing Cardiac Surgery Lin, H. Dong, D. Zheng, K. Xu, Q. J Perianesth Nurs 2024

evidence-based medicine
pain
perioperative care
postoperative delirium
sleep quality

Delirium in the United States: Results From the 2023 Cross-Sectional World Delirium Awareness Day Prevalence Study Lindroth, H. Byrnes, T. Fuchita, M. Hetland, B. Liu, K. Maya, K. McAndrew, N. S. Mulkey, M. A. Nydahl, P. Palakshappa, J. von Haken, R. Psoter, K. J. Oh, E. S. J Acad Consult Liaison Psychiatry 2024

Humans
*Delirium/epidemiology
Cross-Sectional Studies
United States/epidemiology
Prevalence
Male
Female
Aged
Middle Aged
Prospective Studies
Adult
Aged, 80 and over
Intensive Care Units
clinical practice
delirium
health care system
survey

Projection of visual material on postoperative delirium in patients undergoing cardiac surgery: A double blind randomized clinical trial Méndez-Martínez, C. Casado-Verdejo, I. Fernández-Fernández, J. A. Sánchez-Valdeón, L. Bello-Corral, L. Méndez-Martínez, S. Sandoval-Diez, A. Gómez-Salgado, J. García-Suárez, M. Fernández-García, D. Medicine (Baltimore) 2024

Humans
Male
Female
Double-Blind Method
*Cardiac Surgical Procedures/adverse effects
Middle Aged
*Delirium/etiology/epidemiology/diagnosis
*Postoperative Complications/epidemiology/etiology
Aged
Incidence

Prehabilitation for delirium prevention in elderly patients with chronic limb threatening ischemia Meulenbroek, A. L. Lanssens, G. Fourneau, I. Buimer, M. G. de Groot, H. G. W. Veen, E. J. Ho, G. H. van Gorkom, R. Toonders, F. Steyerberg, E. W. Faes, M. C. van der Laan, L. van Alphen, R. Jiran, T. van Overveld, K. Pijl, M. Verbogt, N. J Vasc Surg 2024

Chronic Limb Threatening Ischemia
Delirium
Length of stay (LoS)
Prehabilitation
Prevention
Vascular Surgery

Nutritional status and triglyceride-glucose index influence delirium in elderly heart failure patients Miao, L. Shen, X. Du, Z. Liao, J. Sci Rep 2024

Humans
Male
Female
*Heart Failure/blood/complications
Aged, 80 and over
*Delirium/blood
*Nutritional Status
*Triglycerides/blood
Aged
*Blood Glucose/analysis/metabolism
Retrospective Studies
Risk Factors
Malnutrition/blood
Nutrition Assessment
Delirium
Elderly
Glucose
Heart failure
Nutritional status
Triglyceride

The association of pre-operative biomarkers of endothelial dysfunction with the risk of post-operative neurocognitive disorders: results from the BioCog study Moazzen, S. Janke, J. Slooter, A. J. C. Winterer, G. Spies, C. Pischon, T. Feinkohl, I. BMC Anesthesiol 2024

Humans
Male
Female
*Biomarkers/blood
Aged
*Postoperative Complications/blood/epidemiology
Vascular Cell Adhesion Molecule-1/blood
Endothelium, Vascular/physiopathology
Arginine/analogs & derivatives/blood
Prospective Studies
Follow-Up Studies
Aged, 80 and over
Postoperative Cognitive Complications/blood/epidemiology
Risk Factors
Neuropsychological Tests
Elective Surgical Procedures/adverse effects
Delirium/blood/etiology/epidemiology
von Willebrand Factor/metabolism/analysis
Intercellular Adhesion Molecule-1/blood
Ageing
Biomarkers
Cognitive dysfunction
Endothelial dysfunction
Endothelial function
Postoperative cognitive complications
Postoperative cognitive dysfunction
Postoperative delirium
Surgery

Clinician and Visitor Activity Patterns in an Intensive Care Unit Room: A Study to Examine How Ambient Monitoring Can Inform the Measurement of Delirium Severity and Escalation of Care Nalaie, K. Herasevich, V. Heier, L. M. Pickering, B. W. Diedrich, D. Lindroth, H. J Imaging 2024

computer vision
delirium
health care
hospital
intensive care
object detection
people counting

Incidence of delirium in ophthalmology Ngo, Q. Böhringer, D. Agostini, H. Lapp, T. Reinhard, T. Ophthalmologie 2024

Humans
Incidence
*Delirium/epidemiology/diagnosis
Retrospective Studies
Male
Female
Aged
Middle Aged
*Postoperative Complications/epidemiology
Aged, 80 and over
Germany/epidemiology
Ophthalmology
Ophthalmologic Surgical Procedures/adverse effects/statistics & numerical data
Adult
Follow-Up Studies
Cognitive impairment
Confusion
Outpatient treatment
Patient management
Postoperative complication

Self-efficacy of ICU nurses in delirium care: an analysis of the current status and influencing factors Nie, J. Li, W. J. Jiang, Z. Y. BMC Nurs 2024

Delirium
ICU nurses
Knowledge level of delirium
Questionnaire research
Self-efficacy

Association between intraoperative electroencephalogram burst suppression and postoperative delirium: A systematic review and meta-analysis Park, S. K. Han, D. W. Chang, C. H. Jung, H. Kang, H. Song, Y. Anesthesiology 2024

Electroencephalogram burst suppression

Postoperative delirium

Anesthesia

Intraoperative bust suppression

Association of preoperative to postoperative change in cerebrospinal fluid fibrinogen with postoperative delirium Payne, T. Taylor, J. Kunkel, D. Konieczka, K. Ingram, F. Blennow, K. Zetterberg, H. Pearce, R. A. Meyer-Franke, A. Terrando, N. Akassoglou, K. Sanders, R. D. Lennertz, R. C. BJA Open 2024

anaesthesia
cerebrospinal fluid
delirium
fibrinogen
neurocognitive disorders
surgery

Risk factors for postoperative delirium in adult patients undergoing cardiopulmonary bypass in cardiac surgery Pei, W. Tan, H. Dai, T. Liu, J. Tang, Y. Liu, J. Am J Transl Res 2024

Cardiopulmonary bypass in cardiac surgery
cardiac function
delirium
length of ICU stay
postoperative mechanical ventilation

Impact of Dexmedetomidine on Hemodynamics, Plasma Catecholamine Levels, and Delirium Incidence Among Intubated Patients in the ICU--A Randomized Controlled Trial Qiao, L. Wang, Z. Shen, J. Xing, X. Yuan, H. Ther Clin Risk Manag 2024

delirium
hemodynamics
intensive care unit
plasma norepinephrine

Postoperative Delirium and Neurocognitive Disorders: Updates for Providers Caring for Cancer Patients Ron, D. Deiner, S. Curr Oncol Rep 2024

Humans
*Neoplasms/complications
*Neurocognitive Disorders/etiology
*Delirium/prevention & control/etiology
*Postoperative Complications/prevention & control/etiology
Risk Factors
Cancer
Delayed neurocognitive recovery
Perioperative neurocognitive disorders
Postoperative cognitive dysfunction
Postoperative delirium
Postoperative neurocognitive disorder

Core outcome set for studies evaluating interventions to prevent or treat delirium in long-term care older residents: international key stakeholder informed consensus study Russell, G. Rana, N. Reilly, S. T. Shehadeh, A. Page, V. Siddiqi, N. Rose, L. Age Ageing 2024

Humans
*Delirium/prevention & control/diagnosis/therapy/psychology
*Consensus
*Delphi Technique
*Long-Term Care/methods
Aged
*Stakeholder Participation
Female
Male
Homes for the Aged
Treatment Outcome
Endpoint Determination
Nursing Homes
Aged, 80 and over
core outcome set
delirium
interventions
long-term care
older people
outcomes

Nonpharmacological Prevention and Management of Delirium: Past, Present, and Future Ryan, S. L. Semin Neurol 2024

delirium

EHR

artificial intelligence

risk factors

Cerebrovascular pulsatility indicates preoperative subcortical cognitive impairment and an increased risk for postoperative delirium in elderly patients undergoing elective spine surgery Saar, A. Müller, J. Veser, Y. Behr, F. Rathmann, E. Schroeder, H. W. S. Flöel, A. Müller, J. U. von Sarnowski, B. Fleischmann, R. Front Med (Lausanne) 2024

carotid ultrasound
cognitive impairment
delirium
risk prediction
spine surgery
white matter lesions

Delirium and Weakness Acquired in the Intensive Care Unit: Individual and Combined Effects on 90-Day Mortality in Survivors of Critical Illness Siao, S. F. Zheng, Y. Y. Wei, Y. C. Boehm, L. M. Chen, C. C. J Clin Nurs 2024

delirium
intensive care unit
intensive care unit‐acquired weakness
mortality
survivor of critical illness

The Pathophysiology and Biomarkers of Delirium Smith, C. J. Hodge, D. Harrison, F. E. Williams Roberson, S. Semin Neurol 2024

delirium

biomarkers

neuroimaging

electroencephalography

therapeutic targets

ACR Appropriateness Criteria® Altered Mental Status, Coma, Delirium, and Psychosis: 2024 Update Soares, B. P. Shih, R. Y. Utukuri, P. S. Adamson, M. Austin, M. J. Brown, R. K. J. Burns, J. Cacic, K. Chu, S. Crone, C. Ivanidze, J. Jackson, C. D. Kalnins, A. Potter, C. A. Rosen, S. Soderlund, K. A. Thaker, A. A. Wang, L. L. Policeni, B. J Am Coll Radiol 2024

Humans
*Delirium/diagnosis/diagnostic imaging
United States
*Coma/diagnostic imaging
*Psychotic Disorders/diagnostic imaging
*Societies, Medical
Evidence-Based Medicine
Neuroimaging
Diagnosis, Differential
Consciousness Disorders/diagnostic imaging
Auc
Altered mental status
Appropriateness Criteria
Ct
Mri
appropriate use criteria
delirium
psychosis

Refining Research Diagnostic Criteria for Catatonia Among Delirium, Medical, Affective, and Psychosis Patient Groups Trzepacz, P. T. Franco, J. G. Chakrabarti, S. Ghosh, A. Sahoo, S. Chakravarty, R. Grover, S. J Neuropsychiatry Clin Neurosci 2024

Affective Disorder
Catatonia Diagnosis
Delirium
Diagnostic Approaches
Mood Disorders
Psychotic Disorders

Improving the Recognition and Assessment of ICU Delirium Tuomisto, A. Kennedy, P. J Contin Educ Nurs 2024

*Delirium/diagnosis/prevention & control
Education, Nursing
*Intensive Care Units
Risk Factors

The Relationship between Delirium and Dementia Umoh, M. E. Fitzgerald, D. Vasunilashorn, S. M. Oh, E. S. Fong, T. G. Semin Neurol 2024

delirium

dementia

risk factor

Detecting and managing cognitive impairment in cardiac patients: insights from qualitative interviews with nurses Zhao, E. Bloomfield, J. Lowres, N. Gallagher, R. Contemp Nurse 2024

barriers
cardiac patients
cognitive impairment
delirium
dementia
nurses
qualitative
screening

The Management and Prevention of Delirium in Elderly Patients Hospitalised in Intensive Care Units: A Systematic Review Zaher-Sánchez, S. Satústegui-Dordá, P. J. Ramón-Arbués, E. Santos-Sánchez, J. A. Aguilón-Leiva, J. J. Pérez-Calahorra, S. Juárez-Vela, R. Sufrate-Sorzano, T. Angulo-Nalda, B. Garrote-Cámara, M. E. Santolalla-Arnedo, I. Echániz-Serrano, E. Nurs Rep 2024

Icu
acute confusion
aged
delirium
drug therapy
elderly
intensive care unit
interventions
management
nursing
prevention
treatment

Pharmacological Prevention of Postoperative Delirium in Adults: A Review of Recent Literature White, N. C. Cowart, C. R. Cios, T. J. Curr Neurol Neurosci Rep 2024

Anesthesia
Cognitive dysfunction
Delirium
Dexmedetomidine
Postoperative

DELirium treatment with Transcranial Electrical Stimulation (DELTES): study protocol for a multicentre, randomised, double-blind, sham-controlled trial van der, A. J. Lodema, Y. Ottens, T. H. Schutter, Djlg Emmelot-Vonk, M. H. de Haan, W. van Dellen, E. Tendolkar, I. Slooter, A. J. C. BMJ Open 2024

Humans
Double-Blind Method
*Delirium/therapy/diagnosis
*Transcranial Direct Current Stimulation/methods
*Electroencephalography/methods
Randomized Controlled Trials as Topic
Multicenter Studies as Topic
Netherlands
Middle Aged
Male
Aged
Female
Pilot Projects
Delirium
Electroencephalography
Randomized Controlled Trial

Delirium risk and mortality in people with pre-existing severe mental illness: a retrospective cohort study using linked datasets in England Bauernfreund, Y. Launders, N. Favarato, G. Hayes, J. F. Osborn, D. Sampson, E. L. Psychol Med 2024

Schizophrenia
bipolar disorder
databases
delirium
psychotic disorders

Factors Affecting Delirium Care Core Competency Among Nurses: A Descriptive Correlational Study Bae, K. S. Roh, Y. S. Nurs Health Sci 2024

Humans
*Delirium/therapy/nursing
*Clinical Competence/standards/statistics & numerical data
Female
Male
Surveys and Questionnaires
Adult
Republic of Korea
Nurses/psychology/statistics & numerical data
Middle Aged
Correlation of Data
barriers to delirium care
core competency
knowledge
moral sensitivity

Understanding Barriers to Early Rehabilitation Following the Surgery for Fragility Hip Fractures: A Single-Centre Audit Al-Dahan, T. Murhekar, S. Abed, M. Shinde, K. Cureus 2024

delerium
geriatric hip fracture
physiotherapy
post-op haemoglobin drop
post-operative physiotherapy rehabilitation

The Association of Selective Serotonin Reuptake Inhibitors with Delirium in Post-Operative Adults: A Secondary Analysis of a Post-Operative Dataset with Daily Severity of Illness Adjustment Austin, C. A. Bazemore, I. Yi, J. Glier, S. Carson, S. S. Delirium Commun 2024

Delirium
Postoperative
SSRI

Evaluation of the effects of a team-based systematic prevention and management program for postoperative orthopedic older patients: A retrospective cohort study Yamaguchi, F. Inomata, C. Yoshinaga, N. Sawada, H. Shimamoto, K. Haruta-Tsukamoto, A. PCN Rep 2024

delirium
older patients
postorthopedic surgery
real‐world practice setting

Incidence of Delirium in ICU Patients With and Without COVID-19 in a Costa Rican Hospital Zavaleta-Monestel, E. Martínez-Vargas, E. Chaverri-Fernández, J. Díaz-Madriz, J. P. Fallas-Mora, A. Alvarado-Ajun, P. Rojas-Chinchilla, C. García-Montero, J. Cureus 2024

covid-19
delirium
intensive care unit
mechanical ventilation
sedation

The associations of post-stroke delirium with outcomes: a systematic review and meta-analysis Zhang, G. B. Lv, J. M. Yu, W. J. Li, H. Y. Wu, L. Zhang, S. L. Shi, G. Z. Huang, H. W. BMC Med 2024

Humans
*Delirium/epidemiology/etiology
*Stroke/complications/mortality
Delirium
Meta-analysis
Outcomes
Post-stroke

Preoperative frailty tendency predicts delirium occurrence in older people undergoing spinal surgery Zhang, Y. Zhang, X. Qi, P. Lu, J. Yang, M. BMC Geriatr 2024

Humans
Male
Aged
Female
Prospective Studies
*Frailty/diagnosis
*Delirium/diagnosis/epidemiology/etiology
*Postoperative Complications/diagnosis/epidemiology/etiology
Aged, 80 and over
Pain, Postoperative/diagnosis/epidemiology/etiology
Frail Elderly
Spine/surgery
Middle Aged
Geriatric Assessment/methods
Frailty
Older people
Postoperative delirium
Spinal surgery

Systemic immune inflammatory index (SII) and systemic inflammatory response index (SIRI) as predictors of postoperative delirium in patients undergoing off-pump coronary artery bypass grafting (OPCABG) with cerebral infarction Zhao, B. S. Zhai, W. Q. Ren, M. Zhang, Z. Han, J. G. BMC Surg 2024

Humans
*Coronary Artery Bypass, Off-Pump/adverse effects
Male
Female
Middle Aged
Aged
*Postoperative Complications/diagnosis/etiology/epidemiology/immunology
*Cerebral Infarction/etiology/diagnosis
*Delirium/etiology/diagnosis/epidemiology
Systemic Inflammatory Response Syndrome/etiology/diagnosis
Risk Factors
Retrospective Studies
Predictive Value of Tests
Cerebral infarction
Off-pump coronary artery bypass grafting
Postoperative delirium
Systemic immune inflammatory index
Systemic inflammatory response index

How to predict postoperative delirium in geriatric patients with hip fracture as soon as possible? A retrospective study Zhao, S. Sun, T. Zhang, J. Wang, Y. Guo, Y. Wang, X. BMC Surg 2024

Humans
*Hip Fractures/surgery
Female
Retrospective Studies
Male
Aged, 80 and over
Aged
*Postoperative Complications/diagnosis/etiology/epidemiology
*Delirium/etiology/diagnosis/epidemiology
Risk Factors
*Neutrophils
Lymphocytes
ROC Curve
Delirium
Delirium duration
Hip fracture
Nlr
Risk factors

Clinical investigation into risk factors for delirium post-cardiac surgery and its implications for nursing intervention guided by behavior change theory Zhao, Y. Guo, S. Wang, Z. Dong, Y. Wei, W. Su, Z. J Cardiothorac Surg 2024

Humans
Male
Female
Risk Factors
*Cardiac Surgical Procedures/adverse effects
Middle Aged
*Postoperative Complications/epidemiology/prevention & control
*Delirium/etiology/prevention & control/epidemiology
Aged
Incidence
Retrospective Studies
Behavior change theory
Heart surgery
Nursing intervention
Postoperative delirium

Incidence and risk factors of postoperative delirium in lumbar spinal fusion patients: A National Database analysis Zheng, Y. Wang, J. Liu, Z. Wang, J. Yang, Q. Ren, H. Feng, L. World Neurosurg 2024

Lumbar fusion
National Inpatient Sample
Postoperative delirium
Risk factors

Translation, cultural debugging, and validation of the Chinese version of the Sour Seven Questionnaire: a cross-sectional study Zhu, S. Liu, S. Li, L. Xing, H. Xia, M. Dong, G. Front Med (Lausanne) 2024

Chinese version
Sour Seven Questionnaire
delirium
family member
nursing

Psychiatric Etiologies and Approaches in Altered Mental Status Presentations: Insights from Consultation Liaison Psychiatry Hamm, B. Rosenthal, L. J. Semin Neurol 2024

Altered mental status

Psychiatry

Delirium

 

Bispectral Index Monitoring Effect on Delirium Occurrence and Nursing Quality Improvement in Post-anesthesia Care Unit Patients Recovering From General Anesthesia: A Randomized Controlled Trial Huang, Y. Huang, L. Xu, J. Bao, Y. Qu, Y. Huang, Y. Cureus 2024

bispectral index
depth of anesthesia
nursing quality
post-anesthesia care unit
postoperative delirium

Impact of Frailty and Delirium Among Older Adults Admitted With Acute Decompensated Heart Failure Irizarry-Caro, J. A. Kumar, M. Wang, Q. Rohant, N. Goyal, P. Damluji, A. A. Kirkpatrick, J. N. Kwak, M. J. JACC Adv 2024

acute decompensated heart failure
delirium
disposition at discharge
frailty
mortality
older adults

Improving hospice delirium guideline adoption through an understanding of barriers and facilitators: A mixed-methods study Jackson, C. Malia, C. Zacharias, H. Dyson, J. Johnson, M. J. PLoS One 2024

Humans
*Delirium/therapy/diagnosis
Female
Male
Retrospective Studies
Aged
*Guideline Adherence
Practice Guidelines as Topic
Aged, 80 and over
Hospice Care/standards
Hospices
Middle Aged
Surveys and Questionnaires

Machine learning-based delirium prediction in surgical in-patients: a prospective validation study Jauk, S. Kramer, D. Sumerauer, S. Veeranki, S. P. K. Schrempf, M. Puchwein, P. JAMIA Open 2024
clinical decision support
delirium
electronic health records
prediction algorithms
random forest
Risk factors for postoperative delirium in patients with cardiac surgery Kim, M. S. Kim, S. H. Sci Prog 2024

Humans
Risk Factors
Male
*Delirium/epidemiology/etiology
Female
*Cardiac Surgical Procedures/adverse effects
*Postoperative Complications/epidemiology/etiology
Middle Aged
Aged
*Intensive Care Units/statistics & numerical data
Incidence
Length of Stay
Adult
Cardiac surgery
delirium
risk factors

Delirium in the ICU: how much do we know? A narrative review Liu, S. B. Wu, H. Y. Duan, M. L. Yang, R. L. Ji, C. H. Liu, J. J. Zhao, H. Ann Med 2024

*Delirium/diagnostic imaging/pathology/therapy
*Intensive Care Units/statistics & numerical data
Nervous System Diseases/diagnostic imaging
Biomarkers
Metabolic Diseases/diagnosis
Humans
Delirium
diagnosis
intensive care unit
treatment