What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Interventions for preventing intensive care unit delirium in adults.
- Authors
- Herling, S. F. Greve, I. E. Vasilevskis, E. E. Egerod, I. Bekker Mortensen, C. Møller, A. M. Svenningsen, H. Thomsen, T.
- Year
- 2018
- Journal
- Cochrane Database of Systematic Reviews
- Abstract
Background: Delirium is defined as a disturbance in attention, awareness and cognition with reduced ability to direct, focus, sustain and shift attention, and reduced orientation to the environment. Critically ill patients in the intensive care unit (ICU) frequently develop ICU delirium. It can profoundly affect both them and their families because it is associated with increased mortality, longer duration of mechanical ventilation, longer hospital and ICU stay and long-term cognitive impairment. It also results in increased costs for society. Objectives: To assess existing evidence for the effect of preventive interventions on ICU delirium, in-hospital mortality, the number of delirium- and coma-free days, ventilator-free days, length of stay in the ICU and cognitive impairment. Search methods: We searched CENTRAL, MEDLINE, Embase, BIOSIS, International Web of Science, Latin American Caribbean Health Sciences Literature, CINAHL from 1980 to 11 April 2018 without any language limits. We adapted the MEDLINE search for searching the other databases. Furthermore, we checked references, searched citations and contacted study authors to identify additional studies. We also checked the following trial registries: Current Controlled Trials; ClinicalTrials.gov; and CenterWatch.com (all on 24 April 2018). Selection criteria: We included randomized controlled trials (RCTs) of adult medical or surgical ICU patients receiving any intervention for preventing ICU delirium. The control could be standard ICU care, placebo or both. We assessed the quality of evidence with GRADE. Data collection and analysis: We checked titles and abstracts to exclude obviously irrelevant studies and obtained full reports on potentially relevant ones. Two review authors independently extracted data. If possible we conducted meta-analyses, otherwise we synthesized data narratively. Main results: The electronic search yielded 8746 records. We included 12 RCTs (3885 participants) comparing usual care with the following interventions: commonly used drugs (four studies); sedation regimens (four studies); physical therapy or cognitive therapy, or both (one study); environmental interventions (two studies); and preventive nursing care (one study). We found 15 ongoing studies and five studies awaiting classification. The participants were 48 to 70 years old; 48% to 74% were male; the mean acute physiology and chronic health evaluation (APACHE II) score was 14 to 28 (range 0 to 71; higher scores correspond to more severe disease and a higher risk of death). With the exception of one study, all participants were mechanically ventilated in medical or surgical ICUs or mixed. The studies were overall at low risk of bias. Six studies were at high risk of detection bias due to lack of blinding of outcome assessors. We report results for the two most commonly explored approaches to delirium prevention: pharmacologic and a non-pharmacologic intervention. Haloperidol versus placebo (two RCTs, 1580 participants) The event rate of ICU delirium was measured in one study including 1439 participants. No difference was identified between groups, (risk ratio (RR) 1.01, 95% confidence interval (CI) 0.87 to 1.17) (moderate-quality evidence). Haloperidol versus placebo neither reduced or increased in-hospital mortality, (RR 0.98, 95% CI 0.80 to 1.22; 2 studies; 1580 participants (moderate-quality evidence)); the number of delirium- and coma-free days, (mean difference (MD) -0.60, 95% CI -1.37 to 0.17; 2 studies, 1580 participants (moderate-quality of evidence)); number of ventilator-free days (mean 23.8 (MD -0.30, 95% CI -0.93 to 0.33) 1 study; 1439 participants, (high-quality evidence)); length of ICU stay, (MD 0.18, 95% CI -0.60 to 0.97); 2 studies, 1580 participants; high-quality evidence). None of the studies measured cognitive impairment. In one study there were three serious adverse events in the intervention group and five in the placebo group; in the other there were five serious adverse events and three patients died, one in each group. None of the serious adverse eve ts were judged to be related to interventions received (moderate-quality evidence). Physical and cognitive therapy interventions (one study, 65 participants) The study did not measure the event rate of ICU delirium. A physical and cognitive therapy intervention versus standard care neither reduced nor increased in-hospital mortality, (RR 0.94, 95% CI 0.40 to 2.20, I2; = 0; 1 study, 65 participants; very low-quality evidence); the number of delirium- and coma-free days, (MD -2.8, 95% CI -10.1 to 4.6, I2; = 0; 1 study, 65 participants; very low-quality evidence); the number of ventilator-free days (within the first 28/30 days) was median 27.4 (IQR 0 to 29.2) and 25 (IQR 0 to 28.9); 1 study, 65 participants; very low-quality evidence, length of ICU stay, (MD 1.23, 95% CI -0.68 to 3.14, I2; = 0; 1 study, 65 participants; very low-quality evidence); cognitive impairment measured by the MMSE: Mini-Mental State Examination with higher scores indicating better function, (MD 0.97, 95% CI -0.19 to 2.13, I2; = 0; 1 study, 30 participants; very low-quality evidence); or measured by the Dysexecutive questionnaire (DEX) with lower scores indicating better function (MD -8.76, 95% CI -19.06 to 1.54, I2; = 0; 1 study, 30 participants; very low-quality evidence). One patient experienced acute back pain accompanied by hypotensive urgency during physical therapy. Authors’ conclusions: There is probably little or no difference between haloperidol and placebo for preventing ICU delirium but further studies are needed to increase our confidence in the findings. There is insufficient evidence to determine the effects of physical and cognitive intervention on delirium. The effects of other pharmacological interventions, sedation, environmental, and preventive nursing interventions are unclear and warrant further investigation in large multicentre studies. Five studies are awaiting classification and we identified 15 ongoing studies, evaluating pharmacological interventions, sedation regimens, physical and occupational therapy combined or separately, and environmental interventions, that may alter the conclusions of the review in future.
- PMID
- Keywords
ISRCTN83567338
NCT00095251
NCT00466492
NCT00675363
NCT00824239
NCT01270269
NCT01274819
NCT01739933
NCT01785290
NCT01791296
NCT0196768
NCT01983800
NCT02245256
NCT02548923
NCT02612948
NCT02615340
NCT02932358
NCT03002701
NCT03095443
NCT03125252
NCT03172897
NCT03215745
dexmedetomidine
haloperidol
lorazepam
placebo
adult
APACHE
artificial ventilation
bradycardia
cognitive defect
cognitive therapy
coma
critically ill patient
delirium
environmental intervention
health care cost
hospital mortality
human
intensive care unit
intention to treat analysis
intervention study
length of stay
nursing intervention
outcome assessment
physiotherapy
priority journal
randomized controlled trial (topic)
review
sedation
seizure
sensitivity analysis
treatment duration
ventilator weaning
- Page(s)
- Volume
- 2018
- Issue
- 11
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Priority areas for outcomes improvement among older adults undergoing inpatient general surgery inclusive of geriatric-pertinent complications | Kazaure, H. S. Johnson, K. S. Rosenthal, R. Lagoo-Deenadayalan, S. | World J Surg | 2024 |
Humans |
| Short-Term Outcome of Patients in Delirium at Medical Intensive Care Unit | Khatri, R. Dhungana, S. Ojha, S. P. Khatri, S. Khadka, S. K, C. P. | J Nepal Health Res Counc | 2024 |
Humans |
| Erythropoietin for the prevention of postoperative neurocognitive disorder in older adult patients undergoing total joint arthroplasty: a randomized controlled study | Kim, E. J. Park, K. K. Choi, S. Y. Ju, H. M. Kim, T. L. Kim, J. Kim, S. Y. Koo, B. N. | BMC Anesthesiol | 2024 |
Humans |
| Multilevel factors influencing falls of older patients in hospital: The risk of hospital-induced delirium and the impact of nurse staffing | Kim, J. Lee, E. Lee, S. | Geriatr Nurs | 2024 |
Delirium |
| Preoperative cognitive training for the prevention of postoperative delirium and cognitive dysfunction: a systematic review and meta-analysis | Lau, K. T. Chiu, L. C. S. Fong, J. S. Y. Chan, A. K. M. Ho, K. M. Lee, A. | Perioper Med (Lond) | 2024 |
Cognitive dysfunction |
| Reinforcement learning model for optimizing dexmedetomidine dosing to prevent delirium in critically ill patients | Lee, H. Y. Chung, S. Hyeon, D. Yang, H. L. Lee, H. C. Ryu, H. G. Lee, H. | NPJ Digit Med | 2024 |
Delirium ICU Dexmedetomidine Artificial Intelligence model for Delirium prevention |
| World delirium awareness and quality survey in 2023-a worldwide point prevalence study | Lindroth, H. Liu, K. Szalacha, L. Ashkenazy, S. Bellelli, G. van den Boogaard, M. Caplan, G. Chung, C. R. Elhadi, M. Gurjar, M. Heras-La-Calle, G. Hoffman, M. Jeitziner, M. M. Krewulak, K. Mailhot, T. Morandi, A. Nawa, R. K. Oh, E. S. Collet, M. O. Paulin | Age Ageing | 2024 |
Humans |
| Effects of melatonin on the prevention of delirium in hospitalized older patients: systematic review and meta-analysis | Liu, L. Ma, X. Song, Z. Li, J. Zhao, Y. Meng, C. Wang, S. Miao, G. Liu, P. | BMC Pharmacol Toxicol | 2024 |
*Melatonin/therapeutic use |
| Pharmacologic prophylaxis of postoperative delirium in elderly patients: A network meta-analysis of randomized controlled trials | Liu, T. H. Lin, Y. T. Wu, J. Y. Huang, P. Y. Tsai, W. W. Lai, C. C. Kao, P. H. Su, K. P. | J Psychiatr Res | 2024 |
Delirium |
| Hospitalization and Hospitalized Delirium Are Associated With Decreased Access to Kidney Transplantation and Increased Risk of Waitlist Mortality | Long, J. J. Hong, J. Liu, Y. Nalatwad, A. Li, Y. Ghildayal, N. Johnston, E. A. Schwartzberg, J. Ali, N. Oermann, E. Mankowski, M. Gelb, B. E. Chanan, E. L. Chodosh, J. L. Mathur, A. Segev, D. L. McAdams-DeMarco, M. A. | Clin Transplant | 2024 |
Humans |
| The impact of patient- and family-centered care interventions on intensive care unit outcomes: a meta-analysis of randomized controlled trials | Lv, Y. Li, P. Li, R. Zhang, T. Cai, K. | Braz J Anesthesiol | 2024 |
Critical care |
| Effect of intraoperative dexmedetomidine on heart-type fatty acid binding protein, CK-MB, and cardiac troponin I levels, and postoperative delirium in patients with heart valve replacement | Ma, Z. Liu, Y. Zhang, C. Li, D. Huo, J. Cao, F. | Am J Transl Res | 2024 |
Dexmedetomidine |
| Experience of carers for older people with delirium: a qualitative study | Mahmoud, A. Raghuraman, S. Richards, E. Morgan-Trimmer, S. Goodwin, V. A. Anderson, R. Allan, L. | Aging Ment Health | 2024 |
Delirium |
| Effects of E-Learning Materials on Caregivers' Knowledge about the 3Ds of Geriatric Psychiatry | Mamayson, R. F. Cawalo, W. P. Morales, E. J. P. Morla, R. X. D. Nebrida, K. L. M. Orca, Z. M. P. Pacolor, L. S. R. Paran, D. P. Ramos, A. Y. P. Razon, E. N. S. Sales, Mmac Soriano, Sjmg Tagorda, Akdi Tingson, R. D. B. | Acta Med Philipp | 2024 |
3Ds |
| Knowledge of Delirium Among ICU Nursing Staff: A Cross-sectional Study | Mathew, C. Ashok, A. V. Punnoose, V. P. | Indian J Psychol Med | 2024 |
Delirium |
| Implementation of Evidence-Based International Recommendations Reduces Postoperative Delirium Rate in Patients Undergoing Cardiac Surgery or Interventions: A System-Based Quality Improvement Study | Milz, S. Holaubek, C. Siebel, J. Hulde, N. Wefer, F. Fruend, A. Tigges-Limmer, K. Gummert, J. von Dossow, V. | Rev Cardiovasc Med | 2024 |
cardiac surgery |
| Inflammatory Indices and Their Associations with Postoperative Delirium | Mintz, G. E. Marcantonio, E. R. Walston, J. D. Dillon, S. T. Jung, Y. Trivedi, S. Gu, X. Fong, T. G. Cavallari, M. Touroutoglou, A. Dickerson, B. C. Jones, R. N. Shafi, M. M. Pascual-Leone, A. Travison, T. G. Inouye, S. K. Libermann, T. A. Ngo, L. H. Vasu | J Gerontol A Biol Sci Med Sci | 2024 |
Cam |
| Efficacy of a melatonin receptor agonist and orexin receptor antagonists in preventing delirium symptoms in the olderly patients with stroke: a retrospective study | Miyoshi, Y. Shigetsura, Y. Hira, D. Maki, T. Kawashima, H. Sugita, N. Sugawara, N. Kitada, N. Hirai, M. Kawata, M. Endo, H. Kojima, Y. Ikuta, K. Katsube, Y. Imayoshi, N. Nakagawa, S. Tsuda, M. Terada, T. | J Pharm Health Care Sci | 2024 |
Delirium |
| A Cross-Sectional Survey on Nurses' Utilization of Risk Assessment and Screening for Postoperative Delirium in Older Patients Following Hip Fracture Surgery in Tertiary Hospitals in Jiangsu Province, China | Yang, J. Liu, M. Yang, L. Fang, S. Wang, G. Gu, Z. | Risk Manag Healthc Policy | 2024 |
delirium |
| Reliability and Validity of Hindi Version of the Confusion Assessment Method for Intensive Care Unit (CAM-ICU) for Diagnosis of Delirium: A Cohort Study | Salhotra, R. Bose, A. Srivastava, S. Mohta, M. Pandarinathan, K. Rautela, R. S. | Indian J Crit Care Med | 2024 |
Critical care |
| Classics in Chemical Neuroscience: Deliriant Antihistaminic Drugs | Nerush, M. O. Shevyrin, V. A. Golushko, N. I. Moskalenko, A. M. Rosemberg, D. B. De Abreu, M. S. Yang, L. E. Galstyan, D. S. Lim, L. W. Demin, K. A. Kalueff, A. V. | ACS Chem Neurosci | 2024 |
Animal models |
| Role of Intraoperative Neurophysiological Monitoring in Predicting Postoperative Delirium in Patients Undergoing Carotid Endarterectomy Surgeries | Al-Qudah, A. M. Sivaguru, S. Anetakis, K. Crammond, D. Balzer, J. Subramaniam, K. Sadhasivam, S. Shandal, V. Thirumala, P. | Eur Neurol | 2024 |
Electroencephalography (EEG) Somatosensory Evoked Potentials (SSEP) Intraoperative neurophysiological monitoring (IONM) Postoperative Delirium Carotid Endarterectomy (CEA) surgery |
| Delirium and frailty in older adults: Clinical overlap and biological underpinnings | Bellelli, G. Triolo, F. Ferrara, M. C. Deiner, S. G. Morandi, A. Cesari, M. Davis, D. Marengoni, A. Inzitari, M. Watne, L. O. Rockwood, K. Vetrano, D. L. | J Intern Med | 2024 |
Humans |
| Adherence to optimal delirium management practices in intensive care units in Brazil: a nationwide survey | Bispo, M. M. Souza, Rcds | JBI Evid Implement | 2024 |
Delirium ICU Delirium prevention Delirium treatment Best practices Adherence |
| Patient- and family-centered care in adult ICU (FAM-ICU): A protocol for a feasibility study | Bohart, S. Waldau, T. Andreasen, A. S. Møller, A. M. Thomsen, T. | Acta Anaesthesiol Scand | 2024 |
family |
| Mortality-related factors in older adults with delirium: A prospective observational study | Boran, Y. Altuncı, Y. A. Yalçınlı, S. | Geriatr Nurs | 2024 |
Delirium |
| A Prospective Observational Cohort Study of Language Preference and Preoperative Cognitive Screening in Older Adults: Do Language Disparities Exist in Cognitive Screening and Does the Association Between Test Results and Postoperative Delirium Differ Base | Canales, C. Ramirez, C. M. Yang, S. C. Feinberg, S. A. Grogan, T. R. Whittington, R. A. Sarkisian, C. Cannesson, M. | Anesth Analg | 2024 |
Humans |
| Machine Learning for Prediction of Postoperative Delirium in Adult Patients: A Systematic Review and Meta-analysis | Chen, H. Yu, D. Zhang, J. Li, J. | Clin Ther | 2024 |
Artificial intelligence |
| A Novel Nomogram Developed Based on Preoperative Immune Inflammation-Related Indicators for the Prediction of Postoperative Delirium Risk in Elderly Hip Fracture Cases: A Single-Center Retrospective Cohort Study | Chen, X. Fan, Y. Tu, H. Chen, J. | J Inflamm Res | 2024 |
elderly |
| Serum Albumin Level at Intensive Care Unit Admission and Delirium Duration and Severity in Critically Ill Adults | Chi, R. Perkins, A. J. Khalifeh, Y. Savsani, P. Jawaid, S. Moiz, S. Wang, S. Khan, S. H. Gao, S. Khan, B. A. | Am J Crit Care | 2024 |
Humans |
| Association between exposure to proton pump inhibitors and delirium: a descriptive and disproportionality analysis of VigiBase | Decros, A. Minoc, E. M. Lelong-Boulouard, V. Chrétien, B. Meurant, A. Alexandre, J. Dolladille, C. Villain, C. | BMJ Open | 2024 |
Humans |
| Nutrition care for older adults with delirium: A scoping review | Deeth, S. Stevens, S. Bell, J. Mudge, A. | J Clin Nurs | 2024 |
Humans |
| Benefits of an automated postoperative delirium risk prediction tool combined with non-pharmacological delirium prevention on delirium incidence and length of stay: a before-after analysis based on a quality improvement project | Dodsworth, B. T. Reeve, K. A. Zozman, M. Meier, P. Buddeberg, F. Möller, M. Wildhaber, S. P. Kedda, M. A. Böttger, S. Stocker, R. Gelsomino, N. S. | Age Ageing | 2024 |
Humans |
| Mechanisms underlying delirium in patients with critical illness | Fan, Y. Y. Luo, R. Y. Wang, M. T. Yuan, C. Y. Sun, Y. Y. Jing, J. Y. | Front Aging Neurosci | 2024 |
cognition impairment |
| Early processed electroencephalography for the monitoring of deeply sedated mechanically ventilated critically ill patients | Favre, E. Bernini, A. Miroz, J. P. Abed-Maillard, S. Ramelet, A. S. Oddo, M. | Nurs Crit Care | 2024 |
Humans |
| Post-operative delirium in different age groups and subtypes: a systematic review of case reports | Guo, J. Guo, X. Liu, W. Zhou, A. Han, J. Yi, R. Dong, L. Zhou, Y. | Front Neurol | 2024 |
acute confusion |
| Delirium diagnostic tools in the postoperative setting: A scoping review protocol | Hansen, C. L. Thomsen, T. Tøgern, A. Møller, A. M. Vester-Andersen, M. Overgaard, S. Foss, N. B. Hägi-Pedersen, D. | Acta Anaesthesiol Scand | 2024 |
Humans |
| Assessment of ICU nurses' competency towards delirium among critically ill patients | Hebeshy, M. I. Gaballah, S. H. Ibrahim, N. M. | BMC Nurs | 2024 |
Attitudes |
| Role of glia in delirium: proposed mechanisms and translational implications | Heffernan Á, B. Steinruecke, M. Dempsey, G. Chandran, S. Selvaraj, B. T. Jiwaji, Z. Stavrou, M. | Mol Psychiatry | 2024 |
Delirium Morbidity and mortality Pathophysiology Glial cells Astrocytes Blood brain barrier |
| Using Machine Learning and Electronic Health Records to Identify Neuropsychiatric Risk Scores for Delirium in ICU and General Hospital Settings | Heikal, M. Saad, H. Ghanime, P. M. Bou Dargham, T. Bizri, M. Kobeissy, F. El Hajj, W. Talih, F. | Neuropsychiatr Dis Treat | 2024 |
Delirium |
| A Study of Knowledge and Recognition on Postoperative Delirium Among Postanesthesia Care Unit (PACU) Nurses | Hsu, Y. C. Wang, S. Y. Su, S. F. Lin, L. W. | J Perianesth Nurs | 2024 |
anesthesia |
| Comparing Bispectral Index Monitoring vs Clinical Assessment for Deep Sedation in the ICU: Effects on Delirium Reduction and Sedative Drug Doses-A Randomized Trial | Huespe, I. Giunta, D. Acosta, K. Avila, D. Prado, E. Sanghavi, D. Bisso, I. C. Giannasi, S. Carini, F. C. | Chest | 2024 |
Humans |
| Assessing the Risk of Postoperative Delirium Through Comprehensive Geriatric Assessment and Eastern Cooperative Oncology Group Performance Status of Elderly Patients With Gastric Cancer | Itami, T. Yamamoto, K. Kurokawa, Y. Saito, T. Takahashi, T. Momose, K. Yamashita, K. Tanaka, K. Makino, T. Yasunobe, Y. Akasaka, H. Fujimoto, T. Yamamoto, K. Nakajima, K. Eguchi, H. Doki, Y. | Ann Surg Oncol | 2024 |
Comprehensive geriatric assessment |
| Efficacy and safety of aripiprazole in the treatment of delirium | Jarosz, M. Badura Brzoza, K. A. | Psychiatr Pol | 2024 |
Humans |
| The hot spots and global trends of prevention and treatment in postoperative delirium (POD) from 2004 to 2023: A bibliometric analysis | Jiang, C. Tian, Z. Jiang, M. Xu, C. Mao, M. Feng, S. Yuan, H. | Surg Open Sci | 2024 |
Bibliometric analysis |
| Impact of the Charlson Comorbidity Index on Delirium Outcomes | Kalyan, P. Parulekar, M. | Cureus | 2024 |
charlson comorbidity index |
| Postoperative pain and neurocognitive outcomes after noncardiac surgery: a systematic review and dose-response meta-analysis | Khaled, M. Sabac, D. Fuda, M. Koubaesh, C. Gallab, J. Qu, M. Lo Bianco, G. Shanthanna, H. Paul, J. Thabane, L. Marcucci, M. | Br J Anaesth | 2024 |
delirium |
| Pharmacological Management of Sleep-Wake Disturbances in Delirium | Levinsohn, E. A. Radhakrishnan, V. Euting, H. Kaplan, G. B. | J Clin Pharmacol | 2024 |
Dora |
| The effect of intraoperative midazolam on postoperative delirium in older surgical patients: a prospective, multicentre cohort study | Li, H. Liu, C. Yang, Y. Wu, Q. P. Xu, J. M. Wang, D. F. Sun, J. J. Mao, M. M. Lou, J. S. Liu, Y. H. Cao, J. B. Duan, C. Y. Mi, W. D. | Anesthesiology | 2024 |
Midazolam Benzodiazepine Postoperative Delirium Non-cardiac surgery 3D-CAM |
| Family involvement in preventing delirium in critically ill patients: A systematic review and meta-analysis | Li, J. Fan, Y. Luo, R. Wang, Y. Yin, N. Qi, W. Huang, T. Zhang, J. Jing, J. | Int J Nurs Stud | 2024 |
Critical illness |
| Assessing the Risk of Delirium and Death in Sepsis Using the Braden Score: A Retrospective Study | Li, X. Tang, Y. Bai, Z. Liang, X. Huang, X. Chen, J. Cheng, H. Lyu, J. Wang, Y. | J Clin Nurs | 2024 |
Braden score |
| Nutritional Status and Inflammation as Mediators of Physical Performance and Delirium in Elderly Community-Acquired Pneumonia Patients: A Retrospective Cohort Study | Liao, J. Shen, X. Du, Z. Wang, X. Miao, L. | Clin Interv Aging | 2024 |
Humans |
| Predicting delirium in older adults with community-acquired pneumonia: A retrospective analysis of stress hyperglycemia ratio and its interactions with nutrition and inflammation | Liao, J. Xie, C. Shen, X. Miao, L. | Arch Gerontol Geriatr | 2024 |
Community-acquired pneumonia |
| A Comprehensive Intervention Program for Postoperative Delirium Prevention in Elderly Patients Undergoing Cardiac Surgery | Lin, H. Dong, D. Zheng, K. Xu, Q. | J Perianesth Nurs | 2024 |
evidence-based medicine |
| Delirium in the United States: Results From the 2023 Cross-Sectional World Delirium Awareness Day Prevalence Study | Lindroth, H. Byrnes, T. Fuchita, M. Hetland, B. Liu, K. Maya, K. McAndrew, N. S. Mulkey, M. A. Nydahl, P. Palakshappa, J. von Haken, R. Psoter, K. J. Oh, E. S. | J Acad Consult Liaison Psychiatry | 2024 |
Humans |
| Projection of visual material on postoperative delirium in patients undergoing cardiac surgery: A double blind randomized clinical trial | Méndez-Martínez, C. Casado-Verdejo, I. Fernández-Fernández, J. A. Sánchez-Valdeón, L. Bello-Corral, L. Méndez-Martínez, S. Sandoval-Diez, A. Gómez-Salgado, J. García-Suárez, M. Fernández-García, D. | Medicine (Baltimore) | 2024 |
Humans |
| Prehabilitation for delirium prevention in elderly patients with chronic limb threatening ischemia | Meulenbroek, A. L. Lanssens, G. Fourneau, I. Buimer, M. G. de Groot, H. G. W. Veen, E. J. Ho, G. H. van Gorkom, R. Toonders, F. Steyerberg, E. W. Faes, M. C. van der Laan, L. van Alphen, R. Jiran, T. van Overveld, K. Pijl, M. Verbogt, N. | J Vasc Surg | 2024 |
Chronic Limb Threatening Ischemia |
| Nutritional status and triglyceride-glucose index influence delirium in elderly heart failure patients | Miao, L. Shen, X. Du, Z. Liao, J. | Sci Rep | 2024 |
Humans |
| The association of pre-operative biomarkers of endothelial dysfunction with the risk of post-operative neurocognitive disorders: results from the BioCog study | Moazzen, S. Janke, J. Slooter, A. J. C. Winterer, G. Spies, C. Pischon, T. Feinkohl, I. | BMC Anesthesiol | 2024 |
Humans |
| Clinician and Visitor Activity Patterns in an Intensive Care Unit Room: A Study to Examine How Ambient Monitoring Can Inform the Measurement of Delirium Severity and Escalation of Care | Nalaie, K. Herasevich, V. Heier, L. M. Pickering, B. W. Diedrich, D. Lindroth, H. | J Imaging | 2024 |
computer vision |
| Incidence of delirium in ophthalmology | Ngo, Q. Böhringer, D. Agostini, H. Lapp, T. Reinhard, T. | Ophthalmologie | 2024 |
Humans |
| Self-efficacy of ICU nurses in delirium care: an analysis of the current status and influencing factors | Nie, J. Li, W. J. Jiang, Z. Y. | BMC Nurs | 2024 |
Delirium |
| Association between intraoperative electroencephalogram burst suppression and postoperative delirium: A systematic review and meta-analysis | Park, S. K. Han, D. W. Chang, C. H. Jung, H. Kang, H. Song, Y. | Anesthesiology | 2024 |
Electroencephalogram burst suppression Postoperative delirium Anesthesia Intraoperative bust suppression |
| Association of preoperative to postoperative change in cerebrospinal fluid fibrinogen with postoperative delirium | Payne, T. Taylor, J. Kunkel, D. Konieczka, K. Ingram, F. Blennow, K. Zetterberg, H. Pearce, R. A. Meyer-Franke, A. Terrando, N. Akassoglou, K. Sanders, R. D. Lennertz, R. C. | BJA Open | 2024 |
anaesthesia |
| Risk factors for postoperative delirium in adult patients undergoing cardiopulmonary bypass in cardiac surgery | Pei, W. Tan, H. Dai, T. Liu, J. Tang, Y. Liu, J. | Am J Transl Res | 2024 |
Cardiopulmonary bypass in cardiac surgery |
| Impact of Dexmedetomidine on Hemodynamics, Plasma Catecholamine Levels, and Delirium Incidence Among Intubated Patients in the ICU--A Randomized Controlled Trial | Qiao, L. Wang, Z. Shen, J. Xing, X. Yuan, H. | Ther Clin Risk Manag | 2024 |
delirium |
| Postoperative Delirium and Neurocognitive Disorders: Updates for Providers Caring for Cancer Patients | Ron, D. Deiner, S. | Curr Oncol Rep | 2024 |
Humans |
| Core outcome set for studies evaluating interventions to prevent or treat delirium in long-term care older residents: international key stakeholder informed consensus study | Russell, G. Rana, N. Reilly, S. T. Shehadeh, A. Page, V. Siddiqi, N. Rose, L. | Age Ageing | 2024 |
Humans |
| Nonpharmacological Prevention and Management of Delirium: Past, Present, and Future | Ryan, S. L. | Semin Neurol | 2024 |
delirium EHR artificial intelligence risk factors |
| Cerebrovascular pulsatility indicates preoperative subcortical cognitive impairment and an increased risk for postoperative delirium in elderly patients undergoing elective spine surgery | Saar, A. Müller, J. Veser, Y. Behr, F. Rathmann, E. Schroeder, H. W. S. Flöel, A. Müller, J. U. von Sarnowski, B. Fleischmann, R. | Front Med (Lausanne) | 2024 |
carotid ultrasound |
| Delirium and Weakness Acquired in the Intensive Care Unit: Individual and Combined Effects on 90-Day Mortality in Survivors of Critical Illness | Siao, S. F. Zheng, Y. Y. Wei, Y. C. Boehm, L. M. Chen, C. C. | J Clin Nurs | 2024 |
delirium |
| The Pathophysiology and Biomarkers of Delirium | Smith, C. J. Hodge, D. Harrison, F. E. Williams Roberson, S. | Semin Neurol | 2024 |
delirium biomarkers neuroimaging electroencephalography therapeutic targets |
| ACR Appropriateness Criteria® Altered Mental Status, Coma, Delirium, and Psychosis: 2024 Update | Soares, B. P. Shih, R. Y. Utukuri, P. S. Adamson, M. Austin, M. J. Brown, R. K. J. Burns, J. Cacic, K. Chu, S. Crone, C. Ivanidze, J. Jackson, C. D. Kalnins, A. Potter, C. A. Rosen, S. Soderlund, K. A. Thaker, A. A. Wang, L. L. Policeni, B. | J Am Coll Radiol | 2024 |
Humans |
| Refining Research Diagnostic Criteria for Catatonia Among Delirium, Medical, Affective, and Psychosis Patient Groups | Trzepacz, P. T. Franco, J. G. Chakrabarti, S. Ghosh, A. Sahoo, S. Chakravarty, R. Grover, S. | J Neuropsychiatry Clin Neurosci | 2024 |
Affective Disorder |
| Improving the Recognition and Assessment of ICU Delirium | Tuomisto, A. Kennedy, P. | J Contin Educ Nurs | 2024 |
*Delirium/diagnosis/prevention & control |
| The Relationship between Delirium and Dementia | Umoh, M. E. Fitzgerald, D. Vasunilashorn, S. M. Oh, E. S. Fong, T. G. | Semin Neurol | 2024 |
delirium dementia risk factor |
| Detecting and managing cognitive impairment in cardiac patients: insights from qualitative interviews with nurses | Zhao, E. Bloomfield, J. Lowres, N. Gallagher, R. | Contemp Nurse | 2024 |
barriers |
| The Management and Prevention of Delirium in Elderly Patients Hospitalised in Intensive Care Units: A Systematic Review | Zaher-Sánchez, S. Satústegui-Dordá, P. J. Ramón-Arbués, E. Santos-Sánchez, J. A. Aguilón-Leiva, J. J. Pérez-Calahorra, S. Juárez-Vela, R. Sufrate-Sorzano, T. Angulo-Nalda, B. Garrote-Cámara, M. E. Santolalla-Arnedo, I. Echániz-Serrano, E. | Nurs Rep | 2024 |
Icu |
| Pharmacological Prevention of Postoperative Delirium in Adults: A Review of Recent Literature | White, N. C. Cowart, C. R. Cios, T. J. | Curr Neurol Neurosci Rep | 2024 |
Anesthesia |
| DELirium treatment with Transcranial Electrical Stimulation (DELTES): study protocol for a multicentre, randomised, double-blind, sham-controlled trial | van der, A. J. Lodema, Y. Ottens, T. H. Schutter, Djlg Emmelot-Vonk, M. H. de Haan, W. van Dellen, E. Tendolkar, I. Slooter, A. J. C. | BMJ Open | 2024 |
Humans |
| Delirium risk and mortality in people with pre-existing severe mental illness: a retrospective cohort study using linked datasets in England | Bauernfreund, Y. Launders, N. Favarato, G. Hayes, J. F. Osborn, D. Sampson, E. L. | Psychol Med | 2024 |
Schizophrenia |
| Factors Affecting Delirium Care Core Competency Among Nurses: A Descriptive Correlational Study | Bae, K. S. Roh, Y. S. | Nurs Health Sci | 2024 |
Humans |
| Understanding Barriers to Early Rehabilitation Following the Surgery for Fragility Hip Fractures: A Single-Centre Audit | Al-Dahan, T. Murhekar, S. Abed, M. Shinde, K. | Cureus | 2024 |
delerium |
| The Association of Selective Serotonin Reuptake Inhibitors with Delirium in Post-Operative Adults: A Secondary Analysis of a Post-Operative Dataset with Daily Severity of Illness Adjustment | Austin, C. A. Bazemore, I. Yi, J. Glier, S. Carson, S. S. | Delirium Commun | 2024 |
Delirium |
| Evaluation of the effects of a team-based systematic prevention and management program for postoperative orthopedic older patients: A retrospective cohort study | Yamaguchi, F. Inomata, C. Yoshinaga, N. Sawada, H. Shimamoto, K. Haruta-Tsukamoto, A. | PCN Rep | 2024 |
delirium |
| Incidence of Delirium in ICU Patients With and Without COVID-19 in a Costa Rican Hospital | Zavaleta-Monestel, E. Martínez-Vargas, E. Chaverri-Fernández, J. Díaz-Madriz, J. P. Fallas-Mora, A. Alvarado-Ajun, P. Rojas-Chinchilla, C. García-Montero, J. | Cureus | 2024 |
covid-19 |
| The associations of post-stroke delirium with outcomes: a systematic review and meta-analysis | Zhang, G. B. Lv, J. M. Yu, W. J. Li, H. Y. Wu, L. Zhang, S. L. Shi, G. Z. Huang, H. W. | BMC Med | 2024 |
Humans |
| Preoperative frailty tendency predicts delirium occurrence in older people undergoing spinal surgery | Zhang, Y. Zhang, X. Qi, P. Lu, J. Yang, M. | BMC Geriatr | 2024 |
Humans |
| Systemic immune inflammatory index (SII) and systemic inflammatory response index (SIRI) as predictors of postoperative delirium in patients undergoing off-pump coronary artery bypass grafting (OPCABG) with cerebral infarction | Zhao, B. S. Zhai, W. Q. Ren, M. Zhang, Z. Han, J. G. | BMC Surg | 2024 |
Humans |
| How to predict postoperative delirium in geriatric patients with hip fracture as soon as possible? A retrospective study | Zhao, S. Sun, T. Zhang, J. Wang, Y. Guo, Y. Wang, X. | BMC Surg | 2024 |
Humans |
| Clinical investigation into risk factors for delirium post-cardiac surgery and its implications for nursing intervention guided by behavior change theory | Zhao, Y. Guo, S. Wang, Z. Dong, Y. Wei, W. Su, Z. | J Cardiothorac Surg | 2024 |
Humans |
| Incidence and risk factors of postoperative delirium in lumbar spinal fusion patients: A National Database analysis | Zheng, Y. Wang, J. Liu, Z. Wang, J. Yang, Q. Ren, H. Feng, L. | World Neurosurg | 2024 |
Lumbar fusion |
| Translation, cultural debugging, and validation of the Chinese version of the Sour Seven Questionnaire: a cross-sectional study | Zhu, S. Liu, S. Li, L. Xing, H. Xia, M. Dong, G. | Front Med (Lausanne) | 2024 |
Chinese version |
| Psychiatric Etiologies and Approaches in Altered Mental Status Presentations: Insights from Consultation Liaison Psychiatry | Hamm, B. Rosenthal, L. J. | Semin Neurol | 2024 |
Altered mental status Psychiatry Delirium
|
| Bispectral Index Monitoring Effect on Delirium Occurrence and Nursing Quality Improvement in Post-anesthesia Care Unit Patients Recovering From General Anesthesia: A Randomized Controlled Trial | Huang, Y. Huang, L. Xu, J. Bao, Y. Qu, Y. Huang, Y. | Cureus | 2024 |
bispectral index |
| Impact of Frailty and Delirium Among Older Adults Admitted With Acute Decompensated Heart Failure | Irizarry-Caro, J. A. Kumar, M. Wang, Q. Rohant, N. Goyal, P. Damluji, A. A. Kirkpatrick, J. N. Kwak, M. J. | JACC Adv | 2024 |
acute decompensated heart failure |
| Improving hospice delirium guideline adoption through an understanding of barriers and facilitators: A mixed-methods study | Jackson, C. Malia, C. Zacharias, H. Dyson, J. Johnson, M. J. | PLoS One | 2024 |
Humans |
| Machine learning-based delirium prediction in surgical in-patients: a prospective validation study | Jauk, S. Kramer, D. Sumerauer, S. Veeranki, S. P. K. Schrempf, M. Puchwein, P. | JAMIA Open | 2024 |
clinical decision support
delirium
electronic health records
prediction algorithms
random forest
|
| Risk factors for postoperative delirium in patients with cardiac surgery | Kim, M. S. Kim, S. H. | Sci Prog | 2024 |
Humans |
| Delirium in the ICU: how much do we know? A narrative review | Liu, S. B. Wu, H. Y. Duan, M. L. Yang, R. L. Ji, C. H. Liu, J. J. Zhao, H. | Ann Med | 2024 |
*Delirium/diagnostic imaging/pathology/therapy |